Faculty Research

Explore our research areas below

Imaging of Pathogens and Immune Cells

High-resolution microscopy; Electron microscopy; Imaging in cells and in animals
This group uses a variety of state-of-the-art imaging techniques to understand cellular and molecular mechanisms underlying diseases, study the progression of infectious diseases, identify efficacious antimicrobial agents, develop diagnostic reagents to characterize hidden reservoirs of pathogens, and for the early and accurate detection of infections.

Faculty

Faculty Researcher Research Area
Eric Arts HIV pathogenesis, evolution and vaccine development
Stephen Barr Virus-host interactions of emerging viral pathogens
Gregory Dekaban Development of immunotherapies for cancer, infectious disease and neurotrauma
Jimmy Dikeakos We study the movement of proteins within HIV-1 infected and non-infected cells.
David Heinrichs Pathogenic mechanisms of Staphylococcus aureus (or MRSA)
Bryan Heit Macrophage function in health & disease
Steven Kerfoot B cell immune responses and their role in inflammatory disease
Susan Koval Biology of Predatory Prokaryotes
John McCormick Bacterial toxins of Streptococcus pyogenes and Staphylococcus aureus
Ryan Troyer We study molecular and cellular virology using multiple virus-host systems

Bacteriology & Clinical Bacteriology

Microbiome; Antibiotic resistance; Bacterial ecosystems; Probiotics; Plant microbes
This group focuses on understanding the cellular and molecular mechanisms underlying bacteria-host interactions that drive normal and diseased states in plants and animals. Techniques used include bioinformatics, proteomics, genomics, molecular biology, structural biology, epigenetics, state-of-the-art imaging, animal infection models, and genetics of model organisms.

Faculty

Faculty Researcher Research Area
Jeremy Burton Microbiota associated with Urology
Ana Cabrera Head of the Molecular Microbiology Laboratory at LHSC
Carole Creuzenet Glycobiology, virulence factors and host interactions for gastro-intestinal bacterial pathogens
Johan Delport Rapid methods of identifying bacterial pathogens from patients with suspected bacteremia
David Heinrichs Pathogenic mechanisms of Staphylococcus aureus (or MRSA)
Susan Koval Biology of Predatory Prokaryotes
John McCormick Bacterial toxins of Streptococcus pyogenes and Staphylococcus aureus
Martin McGavin Sensing and response of Staphylococcus aureus to chemical signals of innate immunity
Gregor Reid Probiotic applications to humans and other life-forms
Ze-Chun Yuan Bacteriology, microbial genetics and environmental genomics towards sustainable eco-system

Immunology, Autoimmunity, Inflammation & Transplantation

Immune system responses to pathogens and diseases

This group focuses on a wide range of topics aimed at better understanding the immunological processes underlying human disease, organ failure and transplant organ preservation.

Faculty

Faculty Researcher Research Area
Lillian Barra Pathogenesis of rheumatoid arthritis and associated co-morbidities
Ewa Cairns Our laboratory is interested in rheumatic autoimmune diseases
Lisa Cameron T cell biology and chronic inflammatory disease
Gregory Dekaban Development of immunotherapies for cancer, infectious disease and neurotrauma
Rodney DeKoter Transcription factors, animal models, genetic mutations, leukemia, immune system diseases
Lakshman Gunaratnum Acute Kidney Injury and repair, Kidney transplantation, Tumour immunology
Mansour Haeryfar We investigate innate-like and adaptive T cell responses to cancer, viral pathogens and bacterial infections.
Bryan Heit Macrophage function in health & disease
Chil-Yong Kang Development of vaccines against human viral diseases
Tony Jevnikar Nephrology/Transplantation
Steven Kerfoot B cell immune responses and their role in inflammatory disease
Sung Kim Our research program focuses on the signaling and epigenetic mechanisms of innate immune cells in responding to various microbes, tissue injury and cancers
James Koropatnick Development of small molecule, antisense, and antibody-based drugs to treat cancer
John McCormick Bacterial toxins of Streptococcus pyogenes and Staphylococcus aureus
Jessica Prodger Developing Novels Strategies for HIV Prevention and Cure in Africa
Alp Sener Novel transplant organ preservation strategies using temperature modulation and gasotransmitter therapy with the ultimate goal of improving long term graft function and survival
Bhagirath Singh Regulation of Type 1 diabetes by autoantigens, regulatory T cells and microbes
Kelly Summers Immune responses in various clinical settings including autoimmune diseases, inflammatory disorders/conditions, plus drug efficacy and mechanisms

Cancer & Tumour Biology

Cancer immunology; Cancer treatment; DNA tumour viruses; Cancer gene regulation

This groups investigates the molecular mechanisms of cancer and how the immune system responds to it. This research includes cancer gene regulation, animal models, innate and adaptive T cell responses, and DNA tumour viruses that cause cancer. This research exploits such techniques as bioinformatics, genomics, proteomics, cellular and molecular biology, and animal models.

Faculty

Faculty Researcher Research Area
Rodney DeKoter Transcription factors, animal models, genetic mutations, leukemia, immune system diseases
Lakshman Gunaratnum Acute Kidney Injury and repair, Kidney transplantation, Tumour immunology
Mansour Haeryfar We investigate innate-like and adaptive T cell responses to cancer, viral pathogens and bacterial infections.
James Koropatnick Development of small molecule, antisense, and antibody-based drugs to treat cancer
Joe Mymryk DNA tumor viruses and associated human cancers

Virology & Viral Pathogenesis

Viruses; Animal models of disease

This group focuses on understanding the cellular and molecular mechanisms underlying virus-host interactions that drive normal and diseased states. Techniques used include bioinformatics, proteomics, genomics, molecular biology, structural biology, epigenetics, state-of-the-art imaging, animal infection models, and genetics of model organisms.

Faculty

Faculty Researcher Research Area
Eric Arts HIV pathogenesis, evolution and vaccine development
Stephen Barr Virus-host interactions of emerging viral pathogens
Gregory Dekaban Development of immunotherapies for cancer, infectious disease and neurotrauma
Jimmy Dikeakos We study the movement of proteins within HIV-1 infected and non-infected cells.
Mansour Haeryfar We investigate innate-like and adaptive T cell responses to cancer, viral pathogens and bacterial infections.
Chil-Yong Kang Development of vaccines against human viral diseases
Joe Mymryk DNA tumor viruses and associated human cancers
Jessica Prodger Developing Novels Strategies for HIV Prevention and Cure in Africa
Ryan Troyer We study molecular and cellular virology using multiple virus-host systems

Bioinformatics, Genomics & Genetics

Evolution; Epidemiology; Genomics

This group uses a variety of bioinformatic approaches to better understand host-pathogen interactions, mechanisms of disease, evolution of pathogens, & microbiota compositions. 

Faculty

Faculty Researcher Research Area
Eric Arts HIV pathogenesis, evolution and vaccine development
Stephen Barr Virus-host interactions of emerging viral pathogens
Jeremy Burton Microbiota associated with Urology
Lisa Cameron T cell biology and chronic inflammatory disease
Rodney DeKoter Transcription factors, animal models, genetic mutations, leukemia, immune system diseases
Sung Kim Our research program focuses on the signaling and epigenetic mechanisms of innate immune cells in responding to various microbes, tissue injury and cancers
Martin McGavin Sensing and response of Staphylococcus aureus to chemical signals of innate immunity
Joe Mymryk DNA tumor viruses and associated human cancers
Art Poon Bioinformatics, phylogenetics and the molecular epidemiology of human viruses
Jessica Prodger Developing Novels Strategies for HIV Prevention and Cure in Africa
Gregor Reid Probiotic applications to humans and other life-forms
Ryan Troyer We study molecular and cellular virology using multiple virus-host systems
Ze-Chun Yuan Bacteriology, microbial genetics and environmental genomics towards sustainable eco-system

Vaccine & Drug Discovery

Vaccine development; Animal models of disease and protection; Drug development and testing

This group uses cellular and molecular approaches to develop and test novel vaccines and therapeutic drugs to combat human diseases.

Faculty

Faculty Researcher Research Area
Eric Arts HIV pathogenesis, evolution and vaccine development
Stephen Barr Virus-host interactions of emerging viral pathogens
Gregory Dekaban Development of immunotherapies for cancer, infectious disease and neurotrauma
Jimmy Dikeakos We study the movement of proteins within HIV-1 infected and non-infected cells.
Chil-Yong Kang Development of vaccines against human viral diseases
James Koropatnick Development of small molecule, antisense, and antibody-based drugs to treat cancer
Gregor Reid Probiotic applications to humans and other life-forms
Ryan Troyer We study molecular and cellular virology using multiple virus-host systems