Mansour Haeryfar


Postdoc:  National Institutes of Health (NIH), USA 

PhD:  Dalhousie University, Canada

MSc:  University of Manitoba, Canada

Doctorate (Lab Med):  National University of Tehran, Iran


Office:  Siebens-Drake Research Institute (SDRI) Building, Room 234

Phone: 519.850.2488 (office); 519.661.2111 ext. 86624 (laboratory)


Lab Website: 

Area of Study:

We investigate innate-like and adaptive T cell responses to cancer, viral pathogens and bacterial infections.

Fields of Interest:

-iNKT and MAIT cell responses in health and disease
-CD8+ cytotoxic T cell responses to viral pathogens (e.g., influenza A -  viruses) and tumor antigens
-Cancer immunology and immunotherapy
-T cell-based vaccine design and immunotherapy
-Sepsis-mediated inflammation and immunosuppression

Research Profile

The overarching goal of our research is to further our understanding of conventional and innate-like invariant T cell responses in health and disease. We are particularly interested in cytotoxic T lymphocytes (CTLs), invariant natural killer T (iNKT) cells and mucosa-associated invariant T (MAIT) cells and their therapeutic potentials in various conditions, including malignancies, viral infections and sepsis. We use preclinical models in our mechanistic studies as well as clinical samples in an effort to translate our findings “from the benchtop to the bedside”. The knowledge to be gained is expected to lead to novel disease-tailored immunotherapies and vaccination strategies.

Publication Profile


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