2015 Publications


Finger EC, MacKinley J, Blair M, Oliver LD, Jesso S, Tartaglia MC, Borrie M, Wells J, Dziobek I, Pasternak S, Mitchell DG, Rankin K, Kertesz A, Boxer A. Oxytocin for frontotemporal dementia: a randomized dose-finding study of safety and tolerability. Neurology. 2015 Jan 13;84(2):174-81. doi: 10.1212/WNL.0000000000001133. Epub 2014 Dec 10. PMID: 25503617

Oliver LD, Mitchell DG, Dziobek I, MacKinley J, Coleman K, Rankin KP, Finger EC. Parsing cognitive and emotional empathy deficits for negative and positive stimuli in frontotemporal dementia. Neuropsychologia. 2015 Jan;67:14-26. doi: 10.1016/j.neuropsychologia.2014.11.022. Epub 2014 Nov 29. PMID: 25438032

Strong AL, Shi Z, Strong MJ, Miller DF, Rusch DB, Buechlein AM, Flemington EK, McLachlan JA, Nephew KP, Burow ME, Bunnell BA. Effects of the endocrine-disrupting chemical DDT on self-renewal and differentiation of human mesenchymal stem cells. Environ Health Perspect. 2015 Jan;123(1):42-8. doi: 10.1289/ehp.1408188. Epub 2014 Jul 11. PMID: 25014179

Bharadwaj S, Gofton TE. EEG as a surrogate to brain imaging for diagnosing stroke in morbidly obese patients. J Neurosurg Anesthesiol. 2015 Jan;27(1):77-8. doi: 10.1097/ANA.0000000000000074. No abstract available. PMID: 24755766

Sposato LA. Worsening risk factors and more strokes: the dark side of economic growth? Neurology. 2015 Jan 27;84(4):337-8. doi: 10.1212/WNL.0000000000001196. Epub 2014 Dec 24. No abstract available. PMID: 25540310

Cao S, Strong MJ, Wang X, Moss WN, Concha M, Lin Z, O'Grady T, Baddoo M, Fewell C, Renne R, Flemington EK. High-throughput RNA sequencing-based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project. J Virol. 2015 Jan;89(1):713-29. doi: 10.1128/JVI.02570-14. Epub 2014 Oct 29. PMID: 25355872



Escalaya AL, Tellez-Zenteno JF, Steven DA, Burneo JG. Epilepsy and mortality in Latin America. Seizure. 2015 Feb;25:99-103. doi: 10.1016/j.seizure.2014.09.012. Epub 2014 Oct 5. Review. PMID: 25458096

Hourigan, M. L., McKinnon, N. B., Johnson, M., Rice, C. L., Stashuk, D. W., & Doherty, T. J. (2015). Increased motor unit potential shape variability across consecutive motor unit discharges in the tibialis anterior and vastus medialis muscles of healthy older subjects. Clinical Neurophysiology, 126(12), 2381-2389. doi:10.1016/j.clinph.2015.02.002

Spence JD. Statins and intracerebral hemorrhage. JAMA Neurol. 2015 Feb;72(2):240. doi: 10.1001/jamaneurol.2014.4171. No abstract available. PMID: 25664552

Tibshirani M, Tradewell ML, Mattina KR, Minotti S, Yang W, Zhou H, Strong MJ, Hayward LJ, Durham HD. Cytoplasmic sequestration of FUS/TLS associated with ALS alters histone marks through loss of nuclear protein arginine methyltransferase 1. Hum Mol Genet. 2015 Feb 1;24(3):773-86. doi: 10.1093/hmg/ddu494. Epub 2014 Sep 30. PMID: 25274782


Oveisgharan S, Hachinski V. Executive dysfunction is a strong stroke predictor. J Neurol Sci. 2015 Feb 15;349(1-2):161-7. doi: 10.1016/j.jns.2015.01.010. Epub 2015 Jan 13. PMID: 25614441

MacDonald AA, Naci L, MacDonald PA, Owen AM. Anesthesia and neuroimaging: investigating the neural correlates of unconsciousness. Trends Cogn Sci. 2015 Feb;19(2):100-7. doi: 10.1016/j.tics.2014.12.005. Epub 2015 Jan 12. Review. PMID: 25592916

Spence JD. Are some diets "mass murder"? Mediterranean diet is not to blame for increased carbohydrate intake. BMJ. 2015 Feb 11;350:h613. doi: 10.1136/bmj.h613. No abstract available. PMID: 25672341


Racosta JM, Sposato LA, Morrow SA, Cipriano L, Kimpinski K, Kremenchutzky M. Cardiovascular autonomic dysfunction in multiple sclerosis: a meta-analysis. Mult Scler Relat Disord. 2015 Mar;4(2):104-11. doi: 10.1016/j.msard.2015.02.002. Epub 2015 Feb 23. Review. Erratum in: Mult Scler Relat Disord. 2015 Jul;4(4):385. Kimpiski, Kurt [Corrected to Kimpinski, Kurt]. PMID: 25787186

Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD; Randomized assessment of rapid endovascular treatment of ischemic stroke. ESCAPE Trial Investigators. N Engl J Med. 2015 Mar 12;372(11):1019-30. doi: 10.1056/NEJMoa1414905. Epub 2015 Feb 11. PMID: 25671798

Moszczynski AJ, Gohar M, Volkening K, Leystra-Lantz C, Strong W, Strong MJThr175-phosphorylated tau induces pathologic fibril formation via GSK3β-mediated phosphorylation of Thr231 in vitro. Neurobiol Aging. 2015 Mar;36(3):1590-9. doi: 10.1016/j.neurobiolaging.2014.12.001. Epub 2014 Dec 13. PMID: 25573097

Bharadwaj S, Rizek P, Teefy P, Gofton T. Tit for Tat Brain versus Heart: A Case of Status Epilepticus, Cardiomyopathy, and Stroke. Can J Neurol Sci. 2016 Mar;43(2):347-9. doi: 10.1017/cjn.2015.347. Epub 2015 Dec 14. No abstract available. PMID: 26654568

McKinnon, N. B., Montero-Odasso, M., & Doherty, T. J. (2015). Motor unit loss is accompanied by decreased peak muscle power in the lower limb of older adults. Experimental Gerontology, 70, 111-118. doi:10.1016/j.exger.2015.07.007

Rahimi F, Debicki D, Roberts-South A, Bee C, Bapat P, Jog M. Dynamic decomposition of motion in essential and parkinsonian tremor. Can J Neurol Sci. 2015 Mar;42(2):116-24. doi: 10.1017/cjn.2015.12. Epub 2015 Feb 23. PMID: 25702954

Gooch, C. L., Doherty, T. J., Ming Chan, K., Bromberg, M. B., Lewis, R. A., Stashuk, D. W., . . . Daube, J. R. (2015). Reply to reflection on MUNE. Muscle and Nerve, 51(4), 624. doi:10.1002/mus.24585

Rohrer JD, Nicholas JM, Cash DM, van Swieten J, Dopper E, Jiskoot L, van Minkelen R, Rombouts SA, Cardoso MJ, Clegg S, Espak M, Mead S, Thomas DL, De Vita E, Masellis M, Black SE, Freedman M, Keren R, MacIntosh BJ, Rogaeva E, Tang-Wai D, Tartaglia MC, Laforce R Jr, Tagliavini F, Tiraboschi P, Redaelli V, Prioni S, Grisoli M, Borroni B, Padovani A, Galimberti D, Scarpini E, Arighi A, Fumagalli G, Rowe JB, Coyle-Gilchrist I, Graff C, Fallström M, Jelic V, Ståhlbom AK, Andersson C, Thonberg H, Lilius L, Frisoni GB, Pievani M, Bocchetta M, Benussi L, Ghidoni R, Finger E, Sorbi S, Nacmias B, Lombardi G, Polito C, Warren JD, Ourselin S, Fox NC, Rossor MN, Binetti G. Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis. Lancet Neurol. 2015 Mar;14(3):253-62. doi: 10.1016/S1474-4422(14)70324-2. Epub 2015 Feb 4. Erratum in: Lancet Neurol. 2015 Dec;14(12):1151. Binetti, Giuliano [added]. PMID: 25662776

Fisher BJ, Hu C, Macdonald DR, Lesser GJ, Coons SW, Brachman DG, Ryu S, Werner-Wasik M, Bahary JP, Liu J, Chakravarti A, Mehta M. Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424. Int J Radiat Oncol Biol Phys. 2015 Mar 1;91(3):497-504. doi: 10.1016/j.ijrobp.2014.11.012. Epub 2015 Jan 30. PMID: 25680596

Coutts SB, Dubuc V, Mandzia J, Kenney C, Demchuk AM, Smith EE, Subramaniam S, Goyal M, Patil S, Menon BK, Barber PA, Dowlatshahi D, Field T, Asdaghi N, Camden MC, Hill MD; TEMPO-1 Investigators. Tenecteplase-tissue-type plasminogen activator evaluation for minor ischemic stroke with proven occlusion. Stroke. 2015 Mar;46(3):769-74. doi: 10.1161/STROKEAHA.114.008504. Epub 2015 Feb 12. PMID: 25677596

McLachlan RS. Marijuana: a time-honored but untested treatment for epilepsy. Can J Neurol Sci. 2015 Mar;42(2):88-91. doi: 10.1017/cjn.2015.11. Epub 2015 Feb 26. Review. PMID: 25715711


Sposato LA, Cipriano LE, Saposnik G, Ruíz Vargas E, Riccio PM, Hachinski V. Diagnosis of atrial fibrillation after stroke and transient ischaemic attack: a systematic review and meta-analysis. Lancet Neurol. 2015 Apr;14(4):377-87. doi: 10.1016/S1474-4422(15)70027-X. Epub 2015 Mar 4. Review. PMID: 25748102

Cameron, S., Ball, I., Cepinskas, G., Choong, K., Doherty, T. J., Ellis, C. G., . . . Fraser, D. D. (2015). Early mobilization in the critical care unit: A review of adult and pediatric literature. Journal of Critical Care, 30(4), 664-672. doi:10.1016/j.jcrc.2015.03.032

Nguyen HP, Ayachi F, Lavigne-Pelletier C, Blamoutier M, Rahimi F, Boissy P, Jog M, Duval C. Auto detection and segmentation of physical activities during a Timed-Up-and-Go (TUG) task in healthy older adults using multiple inertial sensors. J Neuroeng Rehabil. 2015 Apr 11;12:36. doi: 10.1186/s12984-015-0026-4. PMID: 25885438

Allen MD, Kimpinski K, Doherty TJ, Rice CL. Decreased muscle endurance associated with diabetic neuropathy may be attributed partially to neuromuscular transmission failure. J Appl Physiol (1985). 2015 Apr 15;118(8):1014-22. doi: 10.1152/japplphysiol.00441.2014. Epub 2015 Feb 5. PMID: 25663671

Spence JD. Measurement of carotid plaque burden. JAMA Neurol. 2015 Apr;72(4):383-4. doi: 10.1001/jamaneurol.2014.3002. Review. No abstract available. PMID: 25686472

Strong MJ, Thompson EM, Roundy N, Selden NR. Use of lumbar laminoplasty vs. laminotomy for transection of the filum terminale does not affect early complication rates or postoperative course. Childs Nerv Syst. 2015 Apr;31(4):597-601. doi: 10.1007/s00381-015-2615-8. Epub 2015 Jan 13. PMID: 25578961

Renton AE, Pliner HA, Provenzano C, Evoli A, Ricciardi R, Nalls MA, Marangi G, Abramzon Y, Arepalli S, Chong S, Hernandez DG, Johnson JO, Bartoccioni E, Scuderi F, Maestri M, Gibbs JR, Errichiello E, Chiò A, Restagno G, Sabatelli M, Macek M, Scholz SW, Corse A, Chaudhry V, Benatar M, Barohn RJ, McVey A, Pasnoor M, Dimachkie MM, Rowin J, Kissel J, Freimer M, Kaminski HJ, Sanders DB, Lipscomb B, Massey JM, Chopra M, Howard JF Jr, Koopman WJ, Nicolle MW, Pascuzzi RM, Pestronk A, Wulf C, Florence J, Blackmore D, Soloway A, Siddiqi Z, Muppidi S, Wolfe G, Richman D, Mezei MM, Jiwa T, Oger J, Drachman DB, Traynor BJ. A genome-wide association study of myasthenia gravis. JAMA Neurol. 2015 Apr;72(4):396-404. doi: 10.1001/jamaneurol.2014.4103. PMID: 25643325

Allen MD, Stashuk DW, Kimpinski K, Doherty TJ, Hourigan ML, Rice CL. Increased neuromuscular transmission instability and motor unit remodelling with diabetic neuropathy as assessed using novel near fibre motor unit potential parameters. Clin Neurophysiol. 2015 Apr;126(4):794-802. doi: 10.1016/j.clinph.2014.07.018. Epub 2014 Aug 18. PMID: 25240249

Spence JD. Aspirin for prevention of cardiovascular events in older Japanese patients. JAMA. 2015 Apr 14;313(14):1473. doi: 10.1001/jama.2015.2574. No abstract available. PMID: 25871676

Rosenfeld J, Strong MJ. Challenges in the Understanding and Treatment of Amyotrophic Lateral Sclerosis/Motor Neuron Disease. Neurotherapeutics. 2015 Apr;12(2):317-25. doi: 10.1007/s13311-014-0332-8. Review. PMID: 25572957


Spence JD. Management of resistant hypertension. CMAJ. 2015 Mar 3;187(4):278. doi: 10.1503/cmaj.1150014. No abstract available. PMID: 25733774

Hachinski V. WORLD BRAIN MEETING The XXII World Congress of Neurology, Santiago, Chile: October 31 - November 5, 2015.  Can J Neurol Sci. 2015 May;42(3):157-8. doi: 10.1017/cjn.2015.33. No abstract available. PMID: 25917754

Spence JD. Dilemmas in diagnosing and managing hypertension: is white coat hypertension benign? Can J Cardiol. 2015 May;31(5):580-2. doi: 10.1016/j.cjca.2015.02.031. Epub 2015 Feb 26. No abstract available. PMID: 25843165

Khaw AV, Angermaier A, Kirsch M, Kessler C, Hosten N, Langner S. Comparing perfusion CT evaluation algorithms for predicting outcome after endovascular treatment in anterior circulation ischaemic stroke. Clin Radiol. 2015 May;70(5):e41-50. doi: 10.1016/j.crad.2015.02.001. Epub 2015 Mar 9. PMID: 25766967

Sawant A, Dadurka K, Overend T, Kremenchutzky M. Systematic review of efficacy of TENS for management of central pain in people with multiple sclerosis. Mult Scler Relat Disord. 2015 May;4(3):219-27. doi: 10.1016/j.msard.2015.03.006. Epub 2015 Apr 8. PMID: 26008938

Spence JD. Management of asymptomatic carotid stenosis. Neurol Clin. 2015 May;33(2):443-57. doi: 10.1016/j.ncl.2014.12.008. Review. PMID: 25907915

Ganjavi H, MacDonald PA. ON-OFF Effects of Dopaminergic Therapy on Psychiatric Symptoms in Parkinson's Disease.J Neuropsychiatry Clin Neurosci. 2015;27(2):e134-9. doi: 10.1176/appi.neuropsych.14030055. Epub 2014 Dec 12. PMID: 25923857

Shadd JD, Ryan BL, Maddocks HL, McKay SD, Moulin DE. Neuropathic pain in a primary care electronic health record database. Eur J Pain. 2015 May;19(5):715-21. doi: 10.1002/ejp.594. Epub 2014 Dec 12. PMID: 25504680

Spence JD. Statins and cataracts: reverse causality? Can J Cardiol. 2015 May;31(5):691.e11. doi: 10.1016/j.cjca.2014.12.018. Epub 2014 Dec 19. No abstract available. PMID: 25795104

Snir JA, Suchy M, Lawrence KS, Hudson RH, Pasternak SH, Bartha R. Prolonged In Vivo Retention of a Cathepsin D Targeted Optical Contrast Agent in a Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2015;48(1):73-87. doi: 10.3233/JAD-150123. PMID: 26401930

Spence JD. Blood pressure control in Canada: the view from a stroke prevention clinic. Can J Cardiol. 2015 May;31(5):593-5. doi: 10.1016/j.cjca.2015.03.005. Epub 2015 Mar 11. No abstract available. PMID: 25936487

LaDonna KA, Ghavanini AA, Venance SLTruths and misinformation: a qualitative exploration of myotonic dystrophy. Can J Neurol Sci. 2015 May;42(3):187-94. doi: 10.1017/cjn.2015.26. Epub 2015 Apr 13. PMID: 25867706 


Ranger A, Diosy D. Seizures in children with dysembryoplastic neuroepithelial tumors of the brain--A review of surgical outcomes across several studies. Childs Nerv Syst. 2015 Jun;31(6):847-55. doi: 10.1007/s00381-015-2675-9. Epub 2015 Mar 21. Review. PMID:25795072

Weishaupt N, Riccio P, Dobbs T, Hachinski VC, Whitehead SN. Characterization of Behaviour and Remote Degeneration Following Thalamic Stroke in the Rat. Int J Mol Sci. 2015 Jun 17;16(6):13921-36. doi: 10.3390/ijms160613921. PMID: 26090717

Arnold DL, Li D, Hohol M, Chakraborty S, Chankowsky J, Alikhani K, Duquette P, Bhan V, Montanera W, Rabinovitch H, Morrish W, Vandorpe R, Guilbert F, Traboulsee A, Kremenchutzky M. Evolving role of MRI in optimizing the treatment of multiple sclerosis: Canadian Consensus recommendations. Mult Scler J Exp Transl Clin. 2015 Jun 10;1:2055217315589775. doi: 10.1177/2055217315589775. eCollection 2015 Jan-Dec. PMID: 28607695

Lin NU, Lee EQ, Aoyama H, Barani IJ, Barboriak DP, Baumert BG, Bendszus M, Brown PD, Camidge DR, Chang SM, Dancey J, de Vries EG, Gaspar LE, Harris GJ, Hodi FS, Kalkanis SN, Linskey ME, Macdonald DR, Margolin K, Mehta MP, Schiff D, Soffietti R, Suh JH, van den Bent MJ, Vogelbaum MA, Wen PY; Response Assessment in Neuro-Oncology (RANO) group.Response assessment criteria for brain metastases: proposal from the RANO group. Lancet Oncol. 2015 Jun;16(6):e270-8. doi: 10.1016/S1470-2045(15)70057-4. Epub 2015 May 27. Review. PMID: 26065612

Strong MJ, Garces J, Tang W, Ware ML. Benign Sacral Metastatic Meningioma: A Rare Entity. Ochsner J. 2015 Summer;15(2):200-2. PMID: 26130988


Robertson BD, Hiebert NM, Seergobin KN, Owen AM, MacDonald PA. Dorsal striatum mediates cognitive control, not cognitive effort per se, in decision-making: An event-related fMRI study. Neuroimage. 2015 Jul 1;114:170-84. doi: 10.1016/j.neuroimage.2015.03.082. Epub 2015 Apr 8. PMID: 25862263

Hall D, Finger EC. Psychotic symptoms in frontotemporal dementia.  Curr Neurol Neurosci Rep. 2015 Jul;15(7):46. doi: 10.1007/s11910-015-0567-8. Review. PMID: 26008815

Bostick GP, Toth C, Carr EC, Stitt LW, Morley-Forster P, Clark AJ, Lynch M, Gordon A, Nathan H, Smyth C, Ware MA, Moulin DE. Physical Functioning and Opioid use in Patients with Neuropathic Pain. Pain Med. 2015 Jul;16(7):1361-8. doi: 10.1111/pme.12702. Epub 2015 Feb 3. PMID: 25645728

Sörös P, Harnadek M, Blake T, Hachinski V, Chan R. Executive dysfunction in patients with transient ischemic attack and minor stroke. J Neurol Sci. 2015 Jul 15;354(1-2):17-20. doi: 10.1016/j.jns.2015.04.022. Epub 2015 Apr 23. PMID: 25979637

Jimenez-Pardo J, Holmes JD, Jenkins ME, Johnson AM. An Examination of the Reliability and Factor Structure of the Physical Activity Scale for Individuals With Physical Disabilities (PASIPD) Among Individuals Living With Parkinson's Disease.  J Aging Phys Act. 2015 Jul;23(3):391-4. doi: 10.1123/japa.2013-0051. Epub 2014 Sep 2. PMID: 25184403

Strong MJ, Rosenlof T, Padmanabha S, Weiner RS, Morgan LR, Ware MI. Treatment of recurrent metastatic uterine leiomyosarcoma of the spine: a multimodality approach using resection, radiosurgery, and chemotherapy. J Neurosurg Spine. 2015 Jul 17:1-6. [Epub ahead of print] PMID: 26186448

 Dykstra AD, Adams SG, Jog M. Examining the relationship between speech intensity and self-rated communicative effectiveness in individuals with Parkinson's disease and hypophonia. J Commun Disord. 2015 Jul-Aug;56:103-12. doi: 10.1016/j.jcomdis.2015.06.012. Epub 2015 Jul 6. PMID: 26188950

Racosta JM, Sposato LA, Morrow SA, Cipriano L, Kimpinski K, Kremenchutzky M. Corrigendum to "Cardiovascular autonomic dysfunction in multiple sclerosis: A meta-analysis" [Mult. Scler. Relat. Disord. 4 (2015) 104-111].  Mult Scler Relat Disord. 2015 Jul;4(4):385. doi: 10.1016/j.msard.2015.05.002. Epub 2015 May 18. No abstract available. PMID: 26195062

Tang W, Tam JH, Seah C, Chiu J, Tyrer A, Cregan SP, Meakin SO, Pasternak SH. Arf6 controls beta-amyloid production by regulating macropinocytosis of the Amyloid Precursor Protein to lysosomes. Mol Brain. 2015 Jul 14;8:41. doi: 10.1186/s13041-015-0129-7. PMID: 26170135

Cao S, Moss W, O'Grady T, Concha M, Strong MJ, Wang X, Yu Y, Baddoo M, Zhang K, Fewell C, Lin Z, Dong Y, Flemington EK. New Noncoding Lytic Transcripts Derived from the Epstein-Barr Virus Latency Origin of Replication, oriP, Are Hyperedited, Bind the Paraspeckle Protein, NONO/p54nrb, and Support Viral Lytic Transcription. J Virol. 2015 Jul;89(14):7120-32. doi: 10.1128/JVI.00608-15. Epub 2015 Apr 29. PMID: 25926645


Spence JD, Pilote L. Importance of sex and gender in atherosclerosis and cardiovascular disease. Atherosclerosis. 2015 Jul;241(1):208-10. doi: 10.1016/j.atherosclerosis.2015.04.806. Epub 2015 Apr 29. No abstract available. PMID: 25980844


Sposato LA, Cipriano LE, Riccio PM, Hachinski V, Saposnik G. Very short paroxysms account for more than half of the cases of atrial fibrillation detected after stroke and TIA: a systematic review and meta-analysis. Int J Stroke. 2015 Aug;10(6):801-7. doi: 10.1111/ijs.12555. Epub 2015 Jul 6. Review. PMID: 26148134

von Podewils F, Runge U, Krüger S, Geithner J, Wang ZI, Khaw AV, Angermaier A, Gaida B, Domin M, Kessler C, Langner S. Diffusion tensor imaging abnormalities in photosensitive juvenile myoclonic epilepsy. Eur J Neurol. 2015 Aug;22(8):1192-200. doi: 10.1111/ene.12725. Epub 2015 Apr 28. PMID: 25919887

Baker J, Kimpinski K. A prospective 1-year study of postural tachycardia and the relationship to non-postural versus orthostatic symptoms. Physiol Behav. 2015 Aug 1;147:227-32. doi: 10.1016/j.physbeh.2015.04.049. Epub 2015 May 1. PMID: 25936824

Cuddy LK, Seah C, Pasternak SH, Rylett RJ. Differential regulation of the high-affinity choline transporter by wild-type and Swedish mutant amyloid precursor protein. J Neurochem. 2015 Aug;134(4):769-82. doi: 10.1111/jnc.13167. Epub 2015 Jun 3. PMID: 25970623


Staudt MD, Di Sebastiano AR, Xu H, Jog M, Schmid S, Foster P, Hebb MO. Advances in Neurotrophic Factor and Cell-Based Therapies for Parkinson's Disease: A Mini-Review. Gerontology. 2016;62(3):371-80. doi: 10.1159/000438701. Epub 2015 Sep 1. Review. PMID: 26330171

Spence JD. Carotid Ultrasound Phenotypes Are Biologically Distinct.Arterioscler Thromb Vasc Biol. 2015 Sep;35(9):1910-3. doi: 10.1161/ATVBAHA.115.306209. No abstract available. PMID: 26310810

Pitz MW, Eisenhauer EA, MacNeil MV, Thiessen B, Easaw JC, Macdonald DR, Eisenstat DD, Kakumanu AS, Salim M, Chalchal H, Squire J, Tsao MS, Kamel-Reid S, Banerji S, Tu D, Powers J, Hausman DF, Mason WP. Phase II study of PX-866 in recurrent glioblastoma. Neuro Oncol. 2015 Sep;17(9):1270-4. doi: 10.1093/neuonc/nou365. Epub 2015 Jan 20. PMID: 25605819

Nucera A, Cipriano L, Hachinski V. Neurovascular Units: A New Cost Effective Model? Can J Neurol Sci. 2015 Sep;42(5):281-2. No  abstract available. PMID: 26594720

Moulin DE, Clark AJ, Gordon A, Lynch M, Morley-Forster PK, Nathan H, Smyth C, Toth C, VanDenKerkhof E, Gilani A, Ware MA. Long-Term Outcome of the Management of Chronic Neuropathic Pain: A Prospective Observational Study. J Pain. 2015 Sep;16(9):852-61. doi: 10.1016/j.jpain.2015.05.011. Epub 2015 Jun 12. PMID: 26080044

Vogelbaum MA, Hu C, Peereboom DM, Macdonald DR, Giannini C, Suh JH, Jenkins RB, Laack NN, Brachman DG, Shrieve DC, Souhami L, Mehta MP. Phase II trial of pre-irradiation and concurrent temozolomide in patients with newly diagnosed anaplastic oligodendrogliomas and mixed anaplastic oligoastrocytomas: long term results of RTOG BR0131. J Neurooncol. 2015 Sep;124(3):413-20. doi: 10.1007/s11060-015-1845-7. Epub 2015 Jun 19. PMID: 26088460

Spence JD. Letter by Spence Regarding Article, "Diet and Stroke: Recent Evidence Supporting a Mediterranean-Style Diet and Food in the Primary Prevention of Stroke". Stroke. 2015 Sep;46(9):e221. doi: 10.1161/STROKEAHA.115.010800. Epub 2015 Aug 6. No abstract available. PMID: 26251245


Ottawa C, Sposato LA, Nabbouh F, Saposnik G; Stroke preparedness in children: translating knowledge into behavioral intent: a systematic review and meta-analysis.  Stroke Outcomes Research Canada (SORCan - www.sorcan.ca). Int J Stroke. 2015 Oct;10(7):1008-13. doi: 10.1111/ijs.12628. Epub 2015 Sep 9. Review. PMID:26352602

Fraser LA, Burneo JG, Fraser JA. Enzyme-inducing antiepileptic drugs and fractures in people with epilepsy: A systematic review. Epilepsy Res. 2015 Oct;116:59-66. doi: 10.1016/j.eplepsyres.2015.07.003. Epub 2015 Jul 8. Review. PMID:26354168

Nikolova S, Bartha R, Parrent AG, Steven DA, Diosy D, Burneo JG. Functional MRI of neuronal activation in epilepsy patients with malformations of cortical development. Epilepsy Res. 2015 Oct;116:1-7. doi: 10.1016/j.eplepsyres.2015.06.012. Epub 2015 Jun 22. PMID:26354161

Hachinski V; World stroke day proclamation: updated. World Stroke Organization. Int J Stroke. 2015 Oct;10 Suppl A100:2-3. doi: 10.1111/ijs.12638. No abstract available. PMID: 26502968

Angermaier A, Khaw AV, Kirsch M, Kessler C, Langner S. Influence of Recanalization and Time of Cerebral Ischemia on Tissue Outcome after Endovascular Stroke Treatment on Computed Tomography Perfusion. J Stroke Cerebrovasc Dis. 2015 Oct;24(10):2306-12. doi: 10.1016/j.jstrokecerebrovasdis.2015.06.025. Epub 2015 Jul 15. PMID:26187789

Mulla SM, Wang L, Khokhar R, Izhar Z, Agarwal A, Couban R, Buckley DN, Moulin DE, Panju A, Makosso-Kallyth S, Turan A, Montori VM, Sessler DI, Thabane L, Guyatt GH, Busse JW. Management of Central Poststroke Pain: Systematic Review of Randomized Controlled Trials. Stroke. 2015 Oct;46(10):2853-60. doi: 10.1161/STROKEAHA.115.010259. Epub 2015 Sep 10. Review. PMID: 26359361

Torralva T, Sposato LA, Riccio PM, Gleichgerrcht E, Roca M, Toledo JB, Trojanowski JQ, Kukull WA, Manes F, Hachinski V. Role of brain infarcts in behavioral variant frontotemporal dementia: Clinicopathological characterization in the National Alzheimer's Coordinating Center database. Neurobiol Aging. 2015 Oct;36(10):2861-8. doi: 10.1016/j.neurobiolaging.2015.06.026. Epub 2015 Jul 3. PMID: 26220367

Snowdon A, Hussein A, Kent R, Pino L, Hachinski V. Comparison of an Electronic and Paper-based Montreal Cognitive Assessment Tool. Alzheimer Dis Assoc Disord. 2015 Oct-Dec;29(4):325-9. doi: 10.1097/WAD.0000000000000069. PMID: 25390882

Maric G, Annis MG, Dong Z, Rose AA, Ng S, Perkins D, MacDonald PA, Ouellet V, Russo C, Siegel PM. GPNMB cooperates with neuropilin-1 to promote mammary tumor growth and engages integrin α5β1 for efficient breast cancer metastasis. Oncogene. 2015 Oct;34(43):5494-504. doi: 10.1038/onc.2015.8. Epub 2015 Mar 16. PMID: 25772243

Ross LE, Vigod S, Wishart J, Waese M, Spence JD, Oliver J, Chambers J, Anderson S, Shields R. Barriers and facilitators to primary care for people with mental health and/or substance use issues: a qualitative study. BMC Fam Pract. 2015 Oct 13;16:135. doi: 10.1186/s12875-015-0353-3. PMID: 26463083

Kamal N, Hill MD, Blacquiere DP, Boulanger JM, Boyle K, Buck B, Butcher K, Camden MC, Casaubon LK, Côté R, Demchuk AM, Dowlatshahi D, Dubuc V, Field TS, Ghrooda E, Gioia L, Gladstone DJ, Goyal M, Gubitz GJ, Harris D, Hart RG, Hunter G, Jeerakathil T, Jin A, Khan K, Lang E, Lanthier S, Lindsay MP, Mackey A, Mandzia J, Mehdiratta M, Minuk J, Oczkowski W, Odier C, Penn A, Perry J, Pettersen JA, Phillips SJ, Poppe AY, Saposnik G, Selchen D, Shamy M, Sharma M, Shoamanesh A, Shuaib A, Silver F, Stotts G, Swartz R, Tamayo A, Teitelbaum J, Verreault S, Wein T, Yip S, Coutts SB. Rapid Assessment and Treatment of Transient Ischemic Attacks and Minor Stroke in Canadian Emergency Departments: Time for a Paradigm Shift. Stroke. 2015 Oct;46(10):2987-90. doi: 10.1161/STROKEAHA.115.010454. Epub 2015 Aug 27. No abstract available. PMID: 26316346

Tam JH, Pasternak SH. Imaging the Intracellular Trafficking of APP with Photoactivatable GFP. J Vis Exp. 2015 Oct 17;(105):e53153. doi: 10.3791/53153. PMID: 26555118

LaDonna KA, Venance SL. Picturing the Experience of Living With Myotonic Dystrophy (DM1): A Qualitative Exploration Using Photovoice. J Neurosci Nurs. 2015 Oct;47(5):285-95. doi: 10.1097/JNN.0000000000000160. PMID: 26348433

Sacco RL, Sandercock P, Endres M, Feigin V, Pandian J, Shinohara Y, Spence JD. Review and prioritization of stroke research recommendations to address the mission of the World Stroke Organization: a call to action from the WSO Research Committee. Int J Stroke. 2015 Oct;10 Suppl A100:4-9. doi: 10.1111/ijs.12625. No abstract available. PMID: 26502969

Rahimi F, Samotus O, Lee J, Jog M. Effective Management of Upper Limb Parkinsonian Tremor by IncobotulinumtoxinA Injections Using Sensor-based Biomechanical Patterns. Tremor Other Hyperkinet Mov (N Y). 2015 Oct 30;5:348. doi: 10.7916/D8BP0270. eCollection 2015. PMID: 26566459

Strong MJ, Laskow T, Nakhoul H, Blanchard E, Liu Y, Wang X, Baddoo M, Lin Z, Yin Q, Flemington EK. Latent Expression of the Epstein-Barr Virus (EBV)-Encoded Major Histocompatibility Complex Class I TAP Inhibitor, BNLF2a, in EBV-Positive Gastric Carcinomas. J Virol. 2015 Oct;89(19):10110-4. doi: 10.1128/JVI.01110-15. Epub 2015 Jul 15. PMID: 26178981

Truelsen T, Krarup LH, Iversen HK, Mensah GA, Feigin VL, Sposato LA, Naghavi M. Causes of Death Data in the Global Burden of Disease Estimates for Ischemic and Hemorrhagic Stroke. Neuroepidemiology. 2015;45(3):152-60. doi: 10.1159/000441084. Epub 2015 Oct 28. Review. PMID: 26505189

Pelz DM, Lownie SP, Lee DH, Boulton MRPlaque morphology (the PLAC Scale) on CT angiography: predicting long-term anatomical success of primary carotid stenting. J Neurosurg. 2015 Oct;123(4):856-61. doi: 10.3171/2014.9.JNS14811. Epub 2015 Mar 27. PMID: 25816084


Gaspard N, Foreman BP, Alvarez V, Cabrera Kang C, Probasco JC, Jongeling AC, Meyers E, Espinera A, Haas KF, Schmitt SE, Gerard EE, Gofton T, Kaplan PW, Lee JW, Legros B, Szaflarski JP, Westover BM, LaRoche SM, Hirsch LJ; New-onset refractory status epilepticus: Etiology, clinical features, and outcome. Critical Care EEG Monitoring Research Consortium (CCEMRC). Neurology. 2015 Nov 3;85(18):1604-13. doi: 10.1212/WNL.0000000000001940. Epub 2015 Aug 21. PMID: 26296517

Kappos L, Kuhle J, Multanen J, Kremenchutzky M, Verdun di Cantogno E, Cornelisse P, Lehr L, Casset-Semanaz F, Issard D, Uitdehaag BM. Factors influencing long-term outcomes in relapsing-remitting multiple sclerosis: PRISMS-15. J Neurol Neurosurg Psychiatry. 2015 Nov;86(11):1202-7. doi: 10.1136/jnnp-2014-310024. Epub 2015 Sep 15. PMID: 26374702

Montero-Odasso, M., Bherer, L., Studenski, S., Gopaul, K., Oteng-Amoako, A., Woolmore-Goodwin, S.,  Doherty, T. J.. . . Camicioli, R. (2015). Mobility and cognition in seniors. report from the 2008 institute of aging (CIHR) mobility and cognition workshop. Canadian Geriatrics Journal, 18(3), 159-167. doi:10.5770/cgj.18.188

Yang C, Bogiatzi C, Spence JD. Risk of Stroke at the Time of Carotid Occlusion. JAMA Neurol. 2015 Nov;72(11):1261-7. doi: 10.1001/jamaneurol.2015.1843. PMID: 26389542

O'Connor PW, Kremenchutzky M. Use of Natalizumab in Patients with Multiple Sclerosis: 2015 Update. Can J Neurol Sci. 2015 Nov;42(6):372-80. doi: 10.1017/cjn.2015.296. Epub 2015 Oct 27. Review. No abstract available. PMID: 26503087

Hachinski V; Stroke and Potentially Preventable Dementias Proclamation: Updated World Stroke Day Proclamation. World Stroke Organization. Stroke. 2015 Nov;46(11):3039-40. doi: 10.1161/STROKEAHA.115.011237. No abstract available. Erratum in: Stroke. 2016 Jan;47(1):e18. Stroke. 2016 Feb;47(2):e37. PMID: 26504189

 Woolley SC, Strong MJ.Frontotemporal Dysfunction and Dementia in Amyotrophic Lateral Sclerosis. Neurol Clin. 2015 Nov;33(4):787-805. doi: 10.1016/j.ncl.2015.07.011. Epub 2015 Sep 8. Review. PMID: 26515622

Alturkustani M, Mandzia J, Watling C, Cooper P, Bahakeem B, Leung A, Gulka I, Howlett C, Hammond R. Acute Myelopathy in a 68-Year-Old Male. Can J Neurol Sci. 2015 Nov;42(6):466-71. No abstract available. PMID: 26866135

Tarride JE, Moulin DE, Lynch M, Clark AJ, Stitt L, Gordon A, Morley-Forster PK, Nathan H, Smyth C, Toth C, Ware MA. Impact on health-related quality of life and costs of managing chronic neuropathic pain in academic pain centres: Results from a one-year prospective observational Canadian study. Pain Res Manag. 2015 Nov-Dec;20(6):327-33. Epub 2015 Oct 16. PMID: 26474381

GBD 2013 DALYs and HALE Collaborators, Sposato LA. Global, regional, and national disability-adjusted life years (DALYs) for 306 diseases and injuries and healthy life expectancy (HALE) for 188 countries, 1990-2013: quantifying the epidemiological transition. Lancet. 2015 Nov 28;386(10009):2145-91. doi: 10.1016/S0140-6736(15)61340-X. Epub 2015 Aug 28. PMID: 26321261


Gofton TE, Kumar H, Roberts-South A, Speechley M, Jog MS. Validity, Reliability, and Insights from Applying the McGill Quality of Life Questionnaire to People Living with Parkinson's Disease (MQoL-PD). J Palliat Care. 2015;31(4):213-20. PMID: 26856121

Cooper PE, Sala-Rabanal M, Lee SJ, Nichols CG. Differential mechanisms of Cantú syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel. J Gen Physiol. 2015 Dec;146(6):527-40. doi: 10.1085/jgp.201511495. PMID: 26621776

Anazodo U, Kewin M, Finger E, Thiessen J, Hadway J, Butler J, Pavlosky W, Prato F, Thompson T, St Lawrence K. Preliminary evaluation of MRI-derived input function for quantitative measurement of glucose metabolism in an integrated PET-MRI. EJNMMI Phys. 2015 Dec;2(Suppl 1):A80. doi: 10.1186/2197-7364-2-S1-A80. No abstract available. PMID:26956342

d'Esterre CD, Boesen ME, Ahn SH, Pordeli P, Najm M, Minhas P, Davari P, Fainardi E, Rubiera M, Khaw AV, Zini A, Frayne R, Hill MD, Demchuk AM, Sajobi TT, Forkert ND, Goyal M, Lee TY, Menon BK. Time-Dependent Computed Tomographic Perfusion Thresholds for Patients With Acute Ischemic Stroke. Stroke. 2015 Dec;46(12):3390-7. doi: 10.1161/STROKEAHA.115.009250. Epub 2015 Oct 29. PMID: 26514186

Theodore Phillips J, Erwin AA, Agrella S, Kremenchutzky M, Kramer JF, Darkes MJ, Kendter J, Abourjaily H, Rana J, Fox RJ. Consensus Management of Gastrointestinal Events Associated with Delayed-Release Dimethyl Fumarate: A Delphi Study. Neurol Ther. 2015 Dec;4(2):137-46. doi: 10.1007/s40120-015-0037-x. Epub 2015 Nov 2. PMID: 26525536

Sposato LA, Kapral MK, Fang J, Gill SS, Hackam DG, Cipriano LE, Hachinski V. Declining Incidence of Stroke and Dementia: Coincidence or Prevention Opportunity? JAMA Neurol. 2015 Dec;72(12):1529-31. doi: 10.1001/jamaneurol.2015.2816. No abstract available. PMID: 26658969

Racosta JM, Kimpinski K, Morrow SA, Kremenchutzky M. Autonomic dysfunction in multiple sclerosis. Auton Neurosci. 2015 Dec;193:1-6. doi: 10.1016/j.autneu.2015.06.001. Epub 2015 Jun 7. Review. PMID:26070809

GBD 2013 DALYs and HALE Collaborators, Sposato LA. Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Dec 5;386(10010):2287-323. doi: 10.1016/S0140-6736(15)00128-2. Epub 2015 Sep 11. PubMed PMID: 26364544; PubMed Central PMCID: PMC4685753.

Caetano FA, Dirk BS, Tam JH, Cavanagh PC, Goiko M, Ferguson SS, Pasternak SH, Dikeakos JD, de Bruyn JR, Heit B. MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures. PLoS Comput Biol. 2015 Dec 11;11(12):e1004634. doi: 10.1371/journal.pcbi.1004634. eCollection 2015 Dec. PMID: 26657340

Kuitwaard K, Hahn AF, Vermeulen M, Venance SL, van Doorn PA. Intravenous immunoglobulin response in treatment-naïve chronic inflammatory demyelinating polyradiculoneuropathy. J Neurol Neurosurg Psychiatry. 2015 Dec;86(12):1331-6. doi: 10.1136/jnnp-2014-309042. Epub 2014 Dec 16. PMID: 25515502