J. Alexander Fraser, MD, FRCPC

fraser

Associate Professor, Departments of Clinical Neurological Sciences and Ophthalmology, Western University
Office: London Health Sciences Centre, University Hospital B7-104
Phone: 519-663-3702
Secretary: Rosanna Rajsp

 

Bio Sketch

Dr. Fraser received his Bachelor of Science degree and MD degree from Dalhousie University in Halifax.  He completed residency training in Neurology at Western University and fellowship training in Neuro-Ophthalmology at Emory University in Atlanta.  He is board-certified in Neurology by both the Royal College of Physicians and Surgeons of Canada and the American Board of Psychiatry and Neurology.

Dr. Fraser is currently an Associate Professor at Western University with a primary appointment in the Department of Clinical Neurological Sciences and a cross-appointment in the Department of Ophthalmology. He joined the Department in 2009. He is a member of the Canadian Neurological Sciences Federation, the American Association of Neurology, and the North American Neuro-Ophthalmology Society.


Research

Dr. Fraser has research interests in optic disc drusen (ODD), idiopathic intracranial hypertension (IIH), optic neuritis, pituitary tumor-related vision loss, vascular neuro-ophthalmology, and the neuro-ophthalmology of Parkinson's disease.  He also has an interest in issues pertaining to resident and medical student education.


Medical Interests

Botox for blepharospasm/hemifacial spasm, Eye Movement Disorders, Optic Nerve Disorders, Pupil and Eyelid Dysfunction, Neuro-ophthalmology


Honours and Awards

  • 2014-present, Fellow, North American Neuro-Opthamology Society
  • 2009, Best Paper by a Fellow, Emory University Opthamology Residents' and Fellows' research Day Scientific Session
  • 2006,  Best Paper by a Resident, CNS Department Residents' Research Day
  • 2003, Dr. Graham Gwyn Memorial Prize in Neurology, Dalhousie University

Publications

PubMed Publications Listing

Publications

Li CMF, Romsa JG, Budhram A, Fraser JA. Fixating with the Paretic Eye: Evidence of "Fixation Duress" on PET Imaging. Ann Neurol. 2021 Oct 30. doi: 10.1002/ana.26261. Epub ahead of print. PMID: 34716720.

Fraser JA, Sibony PA, Petzold A, Thaung C, Hamann S; ODDS Consortium. Peripapillary Hyper-reflective Ovoid Mass-like Structure (PHOMS): An Optical Coherence Tomography Marker of Axoplasmic Stasis in the Optic Nerve Head. J Neuroophthalmol. 2021 Feb 19. doi: 10.1097/WNO.0000000000001203. Epub ahead of print. PMID: 33630781.

Petzold A, Biousse V, Bursztyn L, Costello F, Crum A, Digre K, Fraser C, Fraser JA, Katz B, Jurkute N, Newman N, Lautrup-Battistini J, Lawlor M, Liskova P, Lorenz B, Malmqvist L, Peragallo J, Sibony P, Subramanian P, Rejdak R, Nowomiejska K, Touitou V, Warner J, Wegener M, Wong S, Yu-Wai-Man P, Hamann S. Multirater Validation of Peripapillary Hyperreflective Ovoid Mass-like Structures (PHOMS). Neuroophthalmology. 2020 Jul 16;44(6):413-414. doi: 10.1080/01658107.2020.1760891. PMID: 33408429; PMCID: PMC7746256.

Fraser JA, Rueløkke LL, Malmqvist L, Hamann S. Prevalence of Optic Disc Drusen in Young Patients With Nonarteritic Anterior Ischemic Optic Neuropathy: A 10-Year Retrospective Study. J Neuroophthalmol. 2021 Jun 1;41(2):200-205. doi: 10.1097/WNO.0000000000000974. PMID: 32358432.

Hamann S, Malmqvist L, Wegener M, Fard MA, Biousse V, Bursztyn L, Citirak G, Costello F, Crum AV, Digre K, Fraser JA, Huna-Baron R, Katz B, Lawlor M, Newman NJ, Peragallo JH, Petzold A, Sibony PA, Subramanian PS, Warner JEA, Wong SH, Fraser CL; Optic Disc Drusen Studies Consortium. Young Adults With Anterior Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen Study. Am J Ophthalmol. 2020 Sep;217:174-181. doi: 10.1016/j.ajo.2020.03.052. Epub 2020 Apr 13. PMID: 32298654.

Chan TLH, Kim DD, Sharma M, Lee DH, Fraser JA. Valsalva-triggered pseudotumor cerebri syndrome: Case series and pathogenetic implications. Neurology. 2018 Aug 21;91(8):e746-e750. doi: 10.1212/WNL.0000000000006048. Epub 2018 Jul 18. PMID: 30021914.

Morrow SA, Fraser JA, Day C, Bowman D, Rosehart H, Kremenchutzky M, Nicolle M. Effect of Treating Acute Optic Neuritis With Bioequivalent Oral vs Intravenous Corticosteroids: A Randomized Clinical Trial. JAMA Neurol. 2018 Jun 1;75(6):690-696. doi: 10.1001/jamaneurol.2018.0024. PMID: 29507942; PMCID: PMC5885218.

Malmqvist L, Bursztyn L, Costello F, Digre K, Fraser JA, Fraser C, Katz B, Lawlor M, Petzold A, Sibony P, Warner J, Wegener M, Wong S, Hamann S. The Optic Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc Drusen Using Optical Coherence Tomography. J Neuroophthalmol. 2018 Sep;38(3):299-307. doi: 10.1097/WNO.0000000000000585. PMID: 29095768.

Fraser JA. Teaching Video NeuroImages: Video-ophthalmoscopy: Nystagmus from the inside. Neurology. 2016 Oct 25;87(17):e210. doi: 10.1212/WNL.0000000000003262. PMID: 27777350; PMCID: PMC5089526. 

Fraser JA, Leung AE. Reversibility of MRI features of pseudotumor cerebri syndrome. Can J Neurol Sci. 2014 Jul;41(4):530-2. doi: 10.1017/s0317167100018643. PMID: 24878485.

Fraser JA, Biousse V, Newman NJ. The neuro-ophthalmology of mitochondrial disease. Surv Ophthalmol. 2010 Jul-Aug;55(4):299-334. doi: 10.1016/j.survophthal.2009.10.002. Epub 2010 May 14. PMID: 20471050; PMCID: PMC2989385.

Fraser JA, Bruce BB, Rucker J, Fraser LA, Atkins EJ, Newman NJ, Biousse V. Risk factors for idiopathic intracranial hypertension in men: a case-control study. J Neurol Sci. 2010 Mar 15;290(1-2):86-9. doi: 10.1016/j.jns.2009.11.001. Epub 2009 Nov 30. PMID: 19945715; PMCID: PMC2815168.

Budhram A, Gabril MY, Lee DH, Fraser JA. Hypertrophic Pachymeningitis With Optic Neuropathy Heralding Systemic Vasculitis. Can J Neurol Sci. 2017 Jan;44(1):105-107. doi: 10.1017/cjn.2016.51. Epub 2016 May 17. PubMed PMID: 27184909.

Fraser JA. Teaching Video NeuroImages: Video-ophthalmoscopy: Nystagmus from the inside. Neurology. 2016 Oct 25;87(17):e210. PubMed PMID: 27777350; PubMed Central PMCID: PMC5089526.

Khimdas S, Fraser JA. Abducens neuromyotonia: a delayed neuro-ophthalmic complication of cranial radiation. Can J Ophthalmol. 2016 Oct;51(5):e157-e158. doi: 10.1016/j.jcjo.2016.05.020. Epub 2016 Aug 1. PubMed PMID: 27769345.

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