The Neuromuscular group specializes in the diagnosis and management of patients with neuromuscular diseases. These include diseases of the anterior horn cell or motor neuron, peripheral nerves, neuromuscular junction and muscle. Specific expertise in our clinic includes the diagnosis and management of patients with diseases of:
- Peripheral nerves including hereditary neuropathies, acquired demyelinating neuropathies such as the Guillain-Barré syndrome (GBS), multifocal motor neuropathy with conduction block and chronic inflammatory demyelinating polyneuropathy (CIDP)
- Neuromuscular transmission including myasthenia gravis (MG) and the Lambert Eaton myasthenic syndrome (LEMS)
- Muscle including the inflammatory myopathies, toxic myopathies and hereditary myopathies including myotonic disorders, channelopathies and muscular dystrophies
- The Motor Neuron Disease clinic is a separate entity but is closely related to the Neuromuscular Clinic.
The neuromuscular group is closely associated with the EMG laboratory at University Campus. The EMG laboratory studies over 3,500 patients a year, including specialized testing for complicated disorders of peripheral nerve, neuromuscular transmission or muscle. ALS researchers, teachers and clinicians are also connected with the neuromuscular group.
During scheduled academic half-days, neurology residents will study neuromuscular diseases including the following sub-topics:
- Approach to peripheral neuropathy
- AIDP and CIDP
- Approach to myopathy
- Diseases of the neuromuscular junction and their treatment
- The myotonias
- Neuromuscular pearls
- Clinical examination and investigation for autonomic dysfunction
- Disorders of the autonomic nervous system
- Management of respiratory failure in neuromuscular disease
- Physiological basis of normal EMG/NCS and common EMG/NCS abnormalitites
- Basic neuroscience
- Genetics of inherited neuropathies/myopathies
- Immunopathogenesis of immune-mediated neuropathies
- Autonomic nervous system
- Neuropathology: muscle and nerve pathology
PGY4/5 residents also do 2 to 3 months of EMG/ Neuromuscular clinics
Upon graduating, residents will be experts in:
- Motor Neuron Disease
- Peripheral Neuropathies
- Disorders of the nerve root, and brachial and lumbar plexus
- Neuromuscular Junction Disorders
- Myopathies and muscle disorders
Main Contact: Christen Shoesmith - MD, FRCPC
London Health Sciences Centre
339 Windermere Road
London Ontario Canada
CNS offers training opportunities for residents in neuromuscular research. Opportunities for MSc, PhD, and Postdoctoral candidates are also available upon request. Dr. Kimpinski has acted as a supervisor and co-supervisor for research associates, PhD candidates, and postdoctoral fellows studying neurogenic orthostatic hypotension complicated by supine hypertension, and the impact of chronic inflammatory demyelinating neuropathy (CIDP) on the neuromuscular system in humans. Dr. Nicolle has acted as a supervisor and c-supervisor to graduate and postdoctoral students studying myasthenia gravis.
CNS offers training opportunities for residents in neurodegeneration research. Opportunities for MSc, PhD, and Postdoctoral candidates are also available upon request. Dr. Shoesmith and Dr. Strong act as supervisors to researchers and fellows conducting research on ALS.
If you are interested in conducting neuromuscular research or are interested in assisting in ongoing research by our faculty, visit their bio pages for information on their specific research interests and how to get in touch.
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