The Dr. John H. Kreeft Headache Clinic at University Hospital is dedicated to the diagnosis and management of patients with complicated headache or facial pain problems.

The Clinic participates in trials for the prevention and treatment of headache. The treatment of complicated headaches and facial pain requires a wide array of diagnostic and therapeutic measures. The initial team that assesses patients with complicated headache consists of a nurse, who reviews the patient's history and a neurologist who analyses the history with the nurse and then examines the patient and then with the patient agrees upon an initial diagnostic and therapeutic plan.

Training Opportunities


During scheduled academic half-days, neurology residents will study primary headache syndromes including migraine, cluster, tension and less common headache syndromes such as IIH, intracranial hypotension, SUNCT, post-concussive etc. 

If you are interested in spending a clinic day and/or elective rotation at the headache clinic - please contact Dr. Lik Hang Tommy Chan at tommy.chan@lhsc.on.ca

Learn more about CNS Residency programs.

Research Opportunities

If you are interested in conducting cerebrovascular research or are interested in assisting in ongoing research by our faculty, visit their bio pages for information on their specific research interests and how to get in touch.

If you are interested in conducting headache research or are interesting in assisting in ongoing research, please contact Dr. Lik Hang Tommy Chan at tommy.chan@lhsc.on.ca

Recent Headache Publications

Tzankova V, Becker WJ, Chan TLH. Pharmacologic prevention of migraine. CMAJ. 2023 Feb 6;195(5):E187-E192. doi: 10.1503/cmaj.221607. PMID: 36746481; PMCID: PMC9904820.

Tzankova V, Becker WJ, Chan TLH. Diagnosis and acute management of migraine. CMAJ. 2023 Jan 30;195(4):E153-E158. doi: 10.1503/cmaj.211969. PMID: 36717129; PMCID: PMC9888545.

Chan TLH. OnabotulinumtoxinA Improves Quality of Life in Chronic Migraine: The PREDICT Study. Can J Neurol Sci. 2022 Jul;49(4):477-478. doi: 10.1017/cjn.2021.159. PMID: 35768186.

Chan TLH. New Daily Persistent Headache Responsive to Peripheral Nerve Blocks. Can J Neurol Sci. 2021 Sep 16:1-3. doi: 10.1017/cjn.2021.220. Epub ahead of print. PMID: 34526165.

Chan TLH, Vuong K, Chugh T, Carroll I. Cerebellar tonsillar descent: A diagnostic dilemma between Chiari malformation type 1 and spinal cerebrospinal fluid leak. Heliyon. 2021 Apr 19;7(4):e06795. doi: 10.1016/j.heliyon.2021.e06795. PMID: 33981879; PMCID: PMC8082209.

Chan TLH. Hemicrania continua secondary to pituitary macroadenoma responsive to nerve blocks: A case report. Headache. 2021 May;61(5):798-800. doi: 10.1111/head.14121. PMID: 34105160.

Chan TLH, Hindiyeh N. Hemicrania continua: Indomethacin induced myoclonus. Clin Neurol Neurosurg. 2021 Jul;206:106703. doi: 10.1016/j.clineuro.2021.106703. Epub 2021 May 20. PMID: 34049752.

Zhang N, Chan TLH, Cowan R. Reimagining Headache Fellowships. Headache. 2020 Nov;60(10):2613-2617. doi: 10.1111/head.13965. Epub 2020 Sep 26. PMID: 32979226.

Wolf A, Goncalves S, Salehi F, Bird J, Cooper P, Van Uum S, Lee DH, Rotenberg BW, Duggal N. Quantitative evaluation of headache severity before and after endoscopic transsphenoidal surgery for pituitary adenoma. J Neurosurg. 2016 Jun;124(6):1627-33. doi: 10.3171/2015.5.JNS1576. Epub 2015 Oct 23. PubMed PMID: 26495954.

Gladstone J, Cooper PE. Migraine in Canada… we can and should do better. Can J Neurol Sci. 2010 Sep;37(5):553-4. PubMed PMID: 21059496.

Cooper PE. Migraine and chronic daily headache--we could be doing better. Can J Neurol Sci. 2008 Mar;35(1):2-3. PubMed PMID: 18380271.

Chan TLH, Kim DD, Sharma M, Jog M. Hypoglossal Nerve Palsy Following Chiropractic Neck Manipulation. Can J Neurol Sci. 2019;46(5):633-634. doi:10.1017/cjn.2019.237>

Chan TLH, Romsa J, Steven DA, Burneo JG. Refractory Epilepsy: The Role of Positron Emission Tomography. Can J Neurol Sci. 2018;45(1):30-34. doi:10.1017/cjn.2017.244

Chan TLH, Kim DD, Sharma M, Lee DH, Fraser JA. Valsalva-triggered pseudotumor cerebri syndrome: Case series and pathogenetic implicationsNeurology. 2018;91(8):e746-e750. doi:10.1212/WNL.0000000000006048

Chan TLH, Kim DD, Lanzman B, Peretz A. Horner's syndrome and thunderclap headache [published online ahead of print, 2020 Jul 14]. Can J Neurol Sci. 2020;1-8. doi:10.1017/cjn.2020.147

Chan TLH, Sharma M, Burneo JG. Focal Epilepsy Secondary to Juxtacortical Lesions in Cerebral Autosomal Dominant Arteriopathy with Subacute Infarcts and LeukoencephalopathyCan J Neurol Sci. 2018;45(4):462-463. doi:10.1017/cjn.2018.29

Budhram A, Liu Y, Krawczyk M, Chan TLH, Burneo JG, Hosseini-Moghaddam SM, Shoesmith C. High-dose corticosteroids for acute cytomegalovirus-associated transverse myelitis in the immunocompetent patient: a case report and systematic reviewJ Neurovirol. 2019;25(3):405-409. doi:10.1007/s13365-018-0717-2

Chan TLH, Mayich M, Budhram A, Sallam Y, Becker WJ. Teaching Images in Headache: Concurrent Hypercalcemia-Induced Reversible Cerebral Vasoconstriction Syndrome and Posterior Reversible Encephalopathy SyndromeHeadache. 2019;59(6):933-935. doi:10.1111/head.13528

Chan TLH, Budhram A. Facial Diplegia in Neuroinvasive West Nile Virus InfectionCan J Neurol Sci. 2019;46(4):453-454. doi:10.1017/cjn.2019.46

Chan TLH, Zhang N. Chronic Cannabis Use and Treatment Failure of Onabotulinum Toxin A for Chronic MigraineCan J Neurol Sci. 2019;46(6):785-786. doi:10.1017/cjn.2019.291

Chan TLH, Cartagena AM, Bombassaro AM, Hosseini-Moghaddam SM. Ramsay Hunt Syndrome Associated with Central Nervous System Involvement in an AdultCan J Infect Dis Med Microbiol. 2016;2016:9859816. doi:10.1155/2016/9859816

Chan TLH, Becker WJ, Jog M. Indomethacin-Responsive Idiopathic Red Ear Syndrome: Case Report and PathophysiologyHeadache. 2018;58(2):306-308. doi:10.1111/head.13237

Chan TLH, Hale TD, Steenerson KK. Vestibular Lab Testing: Interpreting the Results in the Headache Patient with DizzinessCurr Neurol Neurosci Rep. 2020;20(6):16. Published 2020 May 19. doi:10.1007/s11910-020-01036-4

Chan TLH, Kim DD, Becker WJ. Cluster Headache with Temporomandibular Joint Pain [published online ahead of print, 2020 Mar 24]. Can J Neurol Sci. 2020;1-2. doi:10.1017/cjn.2020.58

Chan TLH, Kim DD, Becker WJ. New Onset Focal Stabbing Headache Associated With Peripheral Vertigo: A Case ReportHeadache. 2018;58(1):151-153. doi:10.1111/head.13208

Chan TLH, Becker WJ, Hu WY, Amoozegar F. Spontaneous Intracranial Hypotension Induced Headaches and Onabotulinum Toxin A: A Case ReportCan J Neurol Sci. 2018;45(1):111-113. doi:10.1017/cjn.2017.257

Chan TLH, Cowan R, Hindiyeh N, Hashmi S, Lanzman B, Carroll I. Spinal cerebrospinal fluid leak in the context of pars interarticularis fractureBMC Neurol. 2020;20(1):162. Published 2020 Apr 29. doi:10.1186/s12883-020-01740-1

Chan TLH, Cowan RP, Woldeamanuel YW. Calcitonin Gene-Related Peptide Receptor Antagonists (Gepants) for the Acute Treatment of Nausea in Episodic Migraine: A Systematic Review and Meta-Analysis [published online ahead of print, 2020 Jun 9]. Headache. 2020;10.1111/head.13858. doi:10.1111/head.13858

Chan TLH, Kim DD, Hashmi S, Carrol I. Pearls and Oy-sters: Dural defect repair as treatment for refractory headache from CSF leak [published online ahead of print, 2020 Aug 4]. Neurology. 2020;10.1212/WNL.0000000000010476. doi:10.1212/WNL.0000000000010476

Chan TLH, Woldeamanuel YW. Exploring naturally occurring clinical subgroups of post-traumatic headacheJ Headache Pain. 2020;21(1):12. Published 2020 Feb 7. doi:10.1186/s10194-020-1080-2