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PaLM Research Day

Research Day 2017 Group Photo

We held yet another amazing Research Day on March 30th at the Great Hall, Somerville House. Unlike previous years, the Paterson Lecture did not coincide with the Research Day in 2017. However, it did not take anything away from one of the most successful showcases of our research achievements in the Department’s history. The day began with opening remarks from Dr. Subrata Chakrabarti, Chair/Chief of Pathology and Laboratory Medicine. In his remarks, Dr. Chakrabarti reinforced and reaffirmed the Department’s vision and mission. He also provided a snapshot of our accomplishments over the past few years and highlighted a few novel future developments. Following the opening remarks, participants were treated to a lineup of a record-breaking 71 abstract presentations. Almost half of all faculty in our Department served as judges and interacted with our young, talented researchers throughout the day.  There was certainly a buzz and an excitement in the air.  It was great to see the breadth of our research activities.         
 
The day concluded with a celebration of the hard work all presenters put into presenting their research. A number of awards denoting exceptional performance in platform and poster presentation were presented at the Awards’ Ceremony at Windermere Manor.
 
The day was successful because of the effort of the presenters, the 24 judges who devoted their valuable time to interact with the presenters, and the Pathology and Laboratory Medicine Research Day Committee. Special thanks to Kathilyn Allewell, Tracey Koning, Cheryl Campbell, Mellonie Carnahan, Linda Jackson-Boeters, Nancy Chan, Martin Duennwald, Manal Gabril, Zia Khan, Emily Goebel, Jina Kum, Vy Ngo, Terry Robins, Shannon Hubbert, Susan Underhill, and Mair Hughes.

We would like to express a heartfelt thank you to all the judges:

Guest Judges:
Brian Chow (Toronto), Deborah Lenz (London), Dr. Iram Siddiqui (Toronto), Dr. Rebekah Jacques (Toronto).
 
Pathology and Laboratory Medicine Judges:
Drs. Alan Tuck, Art Poon, Bekim Sadikovic, Chandan Chakraborty, Christopher Howlett, Edith Arany, Hon Leong, Joan Knoll, Johan Delport, Lisa Cameron, Manal Gabril, Mark Darling, Martin Duennwald, Nancy Chan, Nikhil Sangle, Rob Hammond, Savita Dhanvantari, Stephanie Frisbee, Sunil Parapuram, and Zia Khan.

winners 2017

Top Row: Dr. Paul Plantinga, Dr. Matthew Cecchini, Dr. Emily Goebel, Farzad Asadi, Hayley Good, Richard Filek
Bottom Row: Brittany Pillon, Jina JY Kum, Maham Bushra, Terry Robins, Anu Thomas


Platform Presentation Awards

Chair's Award for the Best Clinical Science Presentation
This award recognizes a Pathology Resident’s excellence in research design and performance as well as the presentation of the research topic. 
 
2017 Awardee: Dr. Matthew Cecchini
Title of the presentation: The Utility of CDX2 Loss as a Prognostic Marker in Stage II Colon Cancer.
         
Dr. M. Daria Haust Award for the Best Basic Science Presentation
This award recognizes a graduate student’s excellence in research design and performance as well as the presentation of the research topic. This award is given in recognition of Dr. M. Daria Haust’s many achievements in the Department of Pathology at the University of Western Ontario and London Health Sciences Centre. 
 
2017 Awardee: Hayley Good
Title of the presentation: The effect of non-steroidal anti-inflammatory drugs on the initiation of Dclk1+ tuft cell-derived colitis-associated cancer. 

Poster Presentation Awards

Best Clinical Science Poster Presentation Award
This award recognizes a Pathology Resident’s excellence in research design and performance as well as the presentation of the poster. 
 
2017 Awardee: Dr. Paul Plantinga
Title of the presentation: Histological Elucidation of Tumour Deposits in Colorectal Adenocarcinoma.
 
Best Basic Science Poster Presentation Award
This award recognizes a Graduate Student’s excellence in research design and performance as well as the presentation of the poster. 
 
2017 Awardee: Farzad Asadi
Title of the presentation: A novel theory on mechanisms of glucagon secretion from pancreatic alpha cells.
 
Best Basic/Clinical Science Collaborative Poster Presentation
This award recognizes excellence in research design and performance as well as the presentation of a research poster. This award is given to a Graduate Student or a Pathology Resident to recognize collaborative basic and clinical science research. 
 
2017 Awardee: Jina JY Kum
Title of the presentation: Transforming growth factor-β1 pathway regulates differentiation of bone marrow-derived progenitor cells
         
Best Undergraduate Basic Science Poster Presentation
This award recognizes excellence in research design and performance as well as presentation of a research poster by an undergraduate student in Pathology modules of the Bachelor of Medical Science program. 
 
2017 Awardee: Maham Bushra
Title of the presentation: The Effects of Repeated Exposure to Whole Body Vibration on Murine Intervertebral Disc and Knee Joint Health.

Other Awards presented at Research Day

MClSc Graduate Research Award (two awardees)
This award recognizes excellence in research design and performance as well as the presentation of a research poster by a graduate student in the Master of Clinical Science – Pathologist’s Assistant program.
 
2017 Awardee: Terry Robins
Title of the presentation: Suitability of RNA Isolated from Archived Formalin-Fixed, Paraffin-Embedded Oral Dysplastic Lesions for Diagnosis of an HPV Etiology.
 
2017 Awardee: Brittany Pillon
Title of the presentation: Youth suicide age and sex related trends in Ontario First Nations communities: A comparison
 
The Cameron Wallace Graduate Student Award in Pathology
The award recognizes a graduate student’s high achievement in research, course work, and social involvement. 
2017 Awardee: Richard Filek 

Dr. P.C. Raju & Jyoti Shah Resident Research Prize
To recognize the Pathology resident with the best original or research article published by the resident as first author.

2017 Awardee: Dr. Emily Goebel
Title of the publication: Goebel EA, McCluggage WG, Walsh JC, Mitotically Active Sclerosing Stromal Tumor of the Ovary: Report of a Case Series With Parallels to Mitotically Active Cellular Fibroma. International Journal of Gynecological Pathology 2016; 35:549–553.
 
Dr. P.C. Raju & Jyoti Shah Graduate Education Prize
To recognize the Pathology and Laboratory Medicine graduate student with the best first-authored original or research article published.

2017 Awardee: Anu Thomas
Title of the publication: Thomas AA, Feng B, Chakrabarti S. ANRIL: A Regulator of VEGF in Diabetic Retinopathy. Invest Ophthalmol Vis Sci.2017;58:470-480.


Research Day 2016

fire Our 2016 Pathology and Laboratory Medicine Research Day will be held on Thursday, April 7 (Social Science 2050 and Great Hall).  Our Research Day is one of the most rewarding days of the academic year when our trainees, staff, and faculty showcase our activities and research in both basic and clinical science.  Our department is small but rich in talent, ideas, and research capabilities and we hope that you will participate and celebrate our achievements on April 7.

We are fortunate to have Dr. Andrew Fire, a brilliant scientist, deliver the Paterson Lecture at our research day.  Dr. Fire is the Professor of Pathology and Genetics at Stanford University School of Medicine.  His laboratory studies how organisms adapt to genetic changes and how genomes respond to changing conditions.  Among many awards for his pioneering work, Dr. Fire shared the 2006 Nobel Prize in Physiology or Medicine with Craig Mello "for their discovery of RNA interference - gene silencing by double-stranded RNA."  Their work has completely revolutionized the way we think about genetic information. 

Dr. Fire received his undergraduate training in mathematics from the University of California, Berkeley in 1978.  He received his PhD from the Massachusetts Institute of Technology under the mentorship of Nobel laureate geneticist Phillip Sharp.  Dr. Fire then moved to England as the Helen Hay Whitney Postdoctoral Fellow and became a member of the MRC Laboratory of Molecular Biology group headed by Nobel laureate biologist Sydney Brenner.  He became an adjunct professor at Johns Hopkins University in 1989 and later joined Stanford in 2003.  Dr. Fire has made seminal discoveries in genetic information flow and continues his pioneering work to understand RNA interference machinery and its roles in the cell and his work on the identification of triggers and mechanisms used in recognition and response to foreign information.

winners

2016 PaLM Research Day Award Winners:

Platform Presentation Awards
The Chair's Award for Best Clinical Science Presentation
2016 Awardee: Dr. William Stecho, PGY4
Presentation: The role of the Nrf2 antioxidant pathway in cancer
The M. Daria Haust Award Best Basic Science Presentation
This award is given in recognition of Dr. M. Daria Haust’s many achievements in the Department of Pathology at Western and LHSC
2016 Awardee: Niamh Richmond, MSc Candidate
Presentation: Transforming growth factor-β induces pluripotency genes in hemangioma stem cells through repressing T-box 2

Poster Presentation Awards
The Best Clinical Science Poster Presentation 
2016 Awardee: Dr. Matthew Kubica, PGY3
Presentation: Comparative utility of distal and mid esophageal biopsies in the diagnosis of eosinophilic esophagitis: a retrospective analysis

Best Basic Science Poster Presentation 
2016 Awardee: Anu Thomas, PhD Candidate
Presentation: Long noncoding RNA ANRIL regulates VEGF mediated angiogenesis in diabetic complications

Best Basic/Clinical Science Collaborative Poster Presentation
2016 Awardee: Rebecca Sullivan, MSc Candidate
Presentation: Expression of the growth hormone secretagogue receptor 1a and ghrelin in human heart failure

Best Undergraduate Basic Science Poster Presentation
2016 Awardee: Alice Tan
Presentation: Expression levels of growth hormone secretagogue receptor 1a and ghrelin in early diabetes

Other Awards
Master of Clinical Science-Pathologists' Assistant Graduate Research Award
2016 Awardee: Derek Kleinsteuber
Presentation: Pathologic resolution based on treatment of Grade II/III arteritis in post renal transplant biopsies
2016 Awardee: Xusheng Zhang
Presentation: Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and kinase signaling pathways

The Cameron Wallace Graduate Student Award in Pathology
This award recognizes a graduate student's achievement in both Pathology Research and course work. This award is given in recognition of Dr. Cameron Wallace who was the head of the Department of Pathology from 1965 - 1974.
2016 Awardee: Niamh Richmond, MSc Candidate

Research Day 2015

The 2015 Pathology and Laboratory Medicine Research Day was held on Monday, March 30, 2015.  The keynote address was delivered by Dr. Nahum Sonenberg (McGill University).  Dr. Nahum Sonenberg is a world renowned researcher in the field of translation initiation in eukaryotes.  He discovered the mRNA cap-binding protein, eukaryotic translation initiation factor 4E (eIF4E), and has continued to explore the implications of his discovery and has provided critical insights into the role of eIF4E in health and disease. 

2015 PaLM Research Day Awards Winners:

The Chair's Award for Best Clinical Science Presentation by a Resident
2015 Awardee: Dr. Matthew Cecchini
Presentation: Loss of the Retinoblastoma Tumor Suppressor Leads to Improved Outcome in Patients with Lung Adenocarcinoma

The Best Clinical Science Poster Presentation by a Resident
2015 Awardee: Dr. Matthew Kubica
Presentation: Mucosa-Associated Lymphoid Tissue Lymphoma Mimicking an Upper Gastrointestinal Polyp

The M. Daria Haust Award Best Basic Science Presentation by a Graduate Student
This award is given in recognition of Dr. M. Daria Haust’s many achievements in the Department of Pathology at Western and LHSC
2015 Awardee: Milica Krstic
Presentation: The role of transcriptional regulator TBX3 in early breast cancer progression

Best Basic Science Poster Presentation by a Graduate Student
2015 Awardee: Meghan Piccinin
Presentation: Diabetic Marrow Adipogenesis Alters Composition of Stem Cell Niche and Impairs CD133-positive Stem Cell Survival

Best Basic/Clinical Science Collaborative Poster Presentation
2015 Awardee: Yadira Tejeda Saldana
Presentation: Variable Region Sequencing of a Monoclonal Antibody Against Escherichia coli O157.

Master of Clinical Science-Pathologists' Assistant Graduate Research Award
2015 Awardee: Lei Gong
Presentation: Intra-departmental quality assurance program for pathologists’ assistants in surgical pathology
2015 Awardee: Andrew Zhang
Presentation: Is Perineural Invasion in Prostatic Core Biopsies Prognostically Significant?

Best Undergraduate Basic Science Poster
2015 Awardee: Edmund Yim
Presentation: Effects of the Western diet and IUGR on Glucose Homeostasis

The Cameron Wallace Graduate Student Award in Pathology
This award recognizes a graduate student's achievement in both Pathology Research and course work. This award is given in recognition of Dr. Cameron Wallace who was the head of the Department of Pathology from 1965 - 1974.
2015 Awardee: Jina Kum

Research Day 2014

The 2014 Pathology and Laboratory Medicine Research Day was held on March 28th, 2014. The event was attended by over 100 faculty, residents, students, and staff. The day started off with an outstanding keynote address delivered by internationally renowned cancer biologist, Dr Thomas Hudson, President and Scientific Director of the Ontario Institute for Cancer Research. His engaging talk was followed by Pathology trainee platform and poster presentations on a wide range of topics underscoring the multidisciplinary research being carried out in the Department of Pathology and Laboratory Medicine.

2014 PaLM Research Day Awards Winners:

Chairs' Award for the Best Clinical Science Presentation: Will Stecho
Title of presentation: Assessment of Resident Grossing Skills in the Digital Age: Evaluation and Implementation of a Mobile Digital Assessment Tool

Dr. M. Daria Haust Award for the Best Basic Science Presentation: Wahab A. Khan
Title of presentation: Differences in Chromatin Accessibility are present between Homologous Metaphase Chromosomes

Best Clinical Science Poster Presentation Award: Brian A. Schick
Title of presentation: Negative Colorectal Polyp Biopsies: The Utility of Cutting Deeper Levels

Best Basic Science Poster Presentation Award: Milica Krstic
Title of presentation: The role of transcriptional regulator TBX3 in early breast cancer progression

Best Basic/Clinical Science Collaborative Poster Presentation: Jacqueline Cox
Title of presentation: Expression of Human tissue Kallikriens (KLKs) in Polymorphous Low Grade Adenocarcinoma (PLGA)

Best Undergraduate Basic Science Poster Presentation: Kelsey Watson
Title of presentation: Interaction of Primary Human Trabecular Meshwork Cells with Metal Alloy Candidates for Microinvasive Glaucoma Surgery

Research Day Group Photos

Research Day Group Photos 1992 - 2017