Publications

publications

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2018 Publications

    1. Abdelhameed M, Martir DR, Chen S, Xu WZ, Oyeneye OO, Chakrabarti S, Zysman-Colman E, Charpentier PA. Tuning the Optical Properties of Silicon Quantum Dots via Surface Functionalization with Conjugated Aromatic Fluorophores. Sci Rep. 2018 Feb 14;8(1):3050. DOI: 10.1038/s41598-018-21181-8. PMID: 29445234
    2. Adams P, Howlett C, Xenocostas A, Chakrabarti S. Sex-specific analysis post-liver transplantation in hemochromatosis with aplastic anemia and hepatocellular carcinoma. Hepatol Commun. 2017 Nov 11;2(1):13-15. DOI: 10.1002/hep4.1122. eCollection 2018 Jan. PMID: 29404507.
    3. Adeyanju K, Bend JR, Rieder MJ, Dekaban GA. HIV-1 Tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells. Virology Journal, In Press (VIRJ-D-18-00011R2).
    4. Amtul Z, Hill DJ, Arany EJ, Cechetto DF. Altered Insulin/Insulin-Like Growth Factor Signaling in a Comorbid Rat model of Ischemia and β-Amyloid Toxicity.Sci Rep. 2018 Mar 23;8(1):5136. DOI: 10.1038/s41598-018-22985-4. PMID: 29572520.
    5. Arany EJ, Waseem M, Strutt BJ, Chamson-Reig A, Bernardo A, Eng E, Hill DJ.  Direct comparison of the abilities of bone marrow mesenchymal versus hematopoietic stem cellsto reverse hyperglycemia in diabetic NOD.SCID mice.  Islets. 2018;10(4):137-150. DOI: 10.1080/19382014.2018.1480285. Epub 2018 Aug 15.  PMID: 30110202
    6. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B. The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.  Epigenetics. 2017;12(11):923-933. DOI: 10.1080/15592294.2017.1381807. Epub 2017 Nov 7.  PMID: 28933623
    7. Aref-Eshghi E, Bend EG, Hood RL, Schenkel LC, Carere DA, Chakrabarti R, Nagamani SCS, Cheung SW, Campeau PM, Prasad C, Siu VM, Brady L, Tarnopolsky MA, Callen DJ, Innes AM, White SM, Meschino WS, Shuen AY, Paré G, Bulman DE, Ainsworth PJ, Lin H, Rodenhiser DI, Hennekam RC, Boycott KM, Schwartz CE, Sadikovic B. BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes. Nat Commun. 2018 Nov 20;9(1):4885. DOI: 10.1038/s41467-018-07193-y. PMID: 30459321 PMCID: PMC6244416
    8. Aref-Eshghi E, Rodenhiser DI, Schenkel LC, Lin H, Skinner C, Ainsworth P, Pare G, Hood RL, Bulman DE, Kernohan KD, Care4Rare Canada Consortium, Boycott KM, Campeau PM, Schwartz C, Sadikovic B. Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes. Am J Hum Genet. 2018 Jan 4;102(1):156-174. DOI: 10.1016/j.ajhg.2017.12.008. PMID: 29304373.
    9. Aref-Eshghi E, Schenkel LC, Ainsworth P, Lin H, Rodenhiser DI, Cutz JC, Sadikovic B. Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues. Front Oncol. 2018 Apr 23;8:100. DOI: 10.3389/fonc.2018.00100. eCollection 2018. PMID: 29740534.
    10. Barber C, Hammond R, Gula L, Tithecott G, Chahine S.  In Search of Black Swans: Identifying Students at Risk of Failing Licensing Examinations.  Acad Med. 2018 Mar;93(3):478-485. DOI: 10.1097/ACM.0000000000001938  PMID: 28953566
    11. Biswas S, Feng B, Thomas A, Chen S, Aref-Eshghi E, Sadikovic BChakrabarti S.  Endothelin-1 regulation is entangled in a complex web of epigenetic mechanisms in diabetes.  Physiol Res. 2018 Jun 27;67(Supplementum 1):S115-S125. PMID: 29947532
    12. Biswas S, Thomas A , Biao F, Chen S , Gonder J, Chakrabarti S.  Role of Long Non-Coding RNA MALAT1 in the Pathogenesis of Diabetic Retinopathy.  Canad. J. Diab 41(suppl) 159A, 2017.
    13. Biswas S, Thomas A, Feng B, Chen S, E Aref-Eshghi , Gonder J, Sadikovic B, Chakrabarti S. MALAT1 and HOTAIR: Key Epigenetic Regulators in Diabetic Retinopathy.  Diabetes 66 (suppl. 1), https://plan.core-apps.com/tristar_ada18/abstract/807d2f9885450670bb994661e367b251
    14. Biswas S, Thomas AA, Chakrabarti S. LncRNAs: Proverbial Genomic “Junk” or Key Epigenetic Regulators During Cardiac Fibrosis in Diabetes?. Front Cardiovasc Med. 2018 Apr 4;5:28. DOI: 10.3389/fcvm.2018.00028. eCollection 2018. PMID: 29670886.
    15. Biswas S, Thomas AA, Chen S, Aref-Eshghi, Feng B, Gonder J, Sadikovic B, Chakrabarti S. MALAT1: An Epigenetic Regulator of Inflammation in Diabetic Retinopathy. Sci Rep. April 2018;8(1):6526. DOI:10.1038/s41598-018-24907-w. PMID: 29695738.
    16. Brady L, Sadikovic B, Rupar CA, Tarnopolsky MA. Complete elimination of a pathogenic homoplasmic mtDNA mutation in one generation. Mitochondrion. 2018 Feb 1. pii: S1567-7249(17)30328-8. DOI: 10.1016/j.mito.2018.01.010. [Epub ahead of print]. PMID: 29408632.
    17. Brichacek M, Naeem A, Filler G, Hammond R, Yazdani A, Ranger A.  Congenital Calvarial Hemangioma.  J Craniofac Surg. 2018 May 8. DOI: 10.1097/SCS.0000000000004613. [Epub ahead of print]  PMID: 29742579
    18. Broeke NC, Peterson J, Lee J, Martin PA, Farag A, Gomez JA, Moussa M, Gaed M, Chin J, Pautler SE, Ward A, Bauman G, Bartha R, Scholl TJ. Characterization of clinical human prostate cancer lesions using 3.0-T sodium MRI registered to Gleason-graded whole-mount histopathology. J Magn Reson Imaging. 2018 Nov 14. [Epub ahead of print] PMID: 30430700 DOI: 10.1002/jmri.26336
    19. Brooks SD, Hileman SM, Chantler PD, Milde SA, Lemaster KA, Frisbee SJ, Shoemaker JK, Jackson DN, Frisbee JC. Protection from vascular dysfunction in female rats with chronic stress and depressive symptoms. Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1070-H1084. DOI: 10.1152/ajpheart.00647.2017. Epub 2018 Feb 16. PMID:29451821.
    20. Brooks SD, Hileman SM, Chantler PD, Milde SA, Lemaster KA, Frisbee SJ, Shoemaker JK, Jackson DN, Frisbee JC. Protection from chronic stress- and depressive symptom-induced vascular endothelial dysfunction in female rats is abolished by preexisting metabolic disease.Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1085-H1097. DOI: 10.1152/ajpheart.00648.2017. Epub 2018 Feb 16. PMID: 29451819
    21. Cecchini MJ, Hosein K, Howlett C, Joseph M, Mura M. Comprehensive gene expression profiling identifies distinct and overlapping transcriptionalprofiles in non-specific interstitial pneumonia and idiopathic pulmonary fibrosis.  Respir Res. 2018 Aug 15;19(1):153. DOI: 10.1186/s12931-018-0857-1.  PMID: 30111332
    22. Chakrabarti S, Sen S, Lui E.  Effect of ginseng therapy on diabetes and its chronic complications: lessons learned.  J Complement Integr Med. 2017 May 11;14(4). pii: /j/jcim.2017.14.issue-4/jcim-2016-0166/jcim-2016-0166.xml. DOI: 10.1515/jcim-2016-0166.  PMID: 29345436
    23. Darling MR, Alkhasawneh M, Mascarenhas W, Chirila A, Copete M. Oral Hairy Leukoplakia in Patients With No Evidence of Immunosuppression: A Case Series and Review of the Literature J Can Dent Assoc 2018; 84: i8.
    24. Datar R, Prasad AN, Tay KY, Rupar CA, Ohorodnyk P, Miller M, Prasad C. Magnetic resonance imaging in the diagnosis of white matter signal abnormalities. Neuroradiol J. 2018 Jan 1:1971400918764016. DOI: 10.1177/1971400918764016. [Epub ahead of print]. PMID: 29517408
    25. Dhanuthai K, Rojanawatsirivej S, Thosaporn W, Kintarak S, Subarnbhesaj A, Darling M, Kryshtalskyj E, Chiang CP, Shin HI, Choi SY, Lee SS, Aminishakib P. Oral cancer: A multicenter study. Med Oral Patol Oral Cir Bucal. 2018 Jan 1;23(1):e23-e29.  DOI: 10.4317/medoral.21999. PMID: 29274153.
    26. Di Gregorio SE, Duennwald ML. Yeast as a model to study protein misfolding in aged cells. FEMS Yeast Res. 2018 Sep 1;18(6). DOI: 10.1093/femsyr/foy054. PMID: 29905793
    27. Di Meo A, Saleeb R, Wala SJ, Khella HW, Ding Q, Zhai H, Krishan K, Krizova A, Gabril M, Evans A, Brimo F, Pasic MD, Finelli A, Diamandis EP, Yousef GM.  A miRNA-based classification of renal cell carcinoma subtypes by PCR and in situ hybridization.  Oncotarget. 2017 Dec 8;9(2):2092-2104. DOI: 10.18632/oncotarget.23162. eCollection 2018 Jan 5.  PMID: 29416756
    28. Duennwald M, Di Gregorio S. ALS Yeast Models – past success stories and new opportunities. Front Mol Neurosci. 2018 Oct 30;11:394. DOI: 10.3389/fnmol.2018.00394. eCollection 2018. PMID: 30425620 PMCID: PMC6218427
    29. Dickson BC, Antonescu CR, Argyris PP, Bilodeau EA, Bullock MJ, Freedman PD, Gnepp DR, Jordan RC, Koutlas IG, Lee CH, Leong I, Merzianu M, Purgina BM, Thompson LDR, Wehrli B, Wright JM, Swanson D, Zhang L, Bishop JA.  Ectomesenchymal Chondromyxoid Tumor: A Neoplasm Characterized by Recurrent RREB1-MKL2 Fusions.  Am J Surg Pathol. 2018 Jun 15. DOI: 10.1097/PAS.0000000000001096. [Epub ahead of print]  PMID: 29912715
    30. Evetts AM, Shkrum MJ, Tugaleva E. A New Reference Source for Postmortem Body Measurements and Organ Weights in Neonates and Infants: A Statistical Analysis Based on Sudden Death Classification (Part 2).  Am J Forensic Med Pathol. 2018 May 24. DOI: 10.1097/PAF.0000000000000401. [Epub ahead of print]  PMID: 29794804
    31. Feng B, Chen S, Chakrabarti S.  Long non-coding RNA ZFAS1 in Diabetic Cardiomyopathy.  Diabetes 66 (suppl. 1). https://plan.core-apps.com/tristar_ada18/abstract/807d2f9885450670bb994661e36eae9b
    32. Filler G, Taheri S, McIntyre C, Smith C, Subramanian L, Fusch G, Fusch C.  Chronic kidney disease stage affects small, dense low-density lipoprotein but not glycated low-density lipoprotein in younger chronic kidney disease patients: a cross-sectional study.  Clin Kidney J. 2018 Jun;11(3):383-388. DOI: 10.1093/ckj/sfx115. Epub 2017 Oct 12.  PMID: 29992019
    33. Filler G, Licht C, Huang SS. Is there a case for eculizumab for pediatric renal transplantation? Pediatr Transplant. 2018 Feb 7. DOI: 10.1111/petr.13128. [Epub ahead of print]. PMID: 29417722.
    34. Florez ID, Brouwers M, Solh Z. Knowledge translation in transfusion medicine. Part 2: Selecting the knowledge and identifying the barriers. Transfusion. 2018 May;58(5):1097-1099. DOI: 10.1111/trf.14505. Epub 2018 Feb 15. PMID: 29446448.
    35. Frisbee SJ, Singh SS, Jackson DN, Lemaster KA, Milde SA, Shoemaker JK, Frisbee JC. Beneficial Pleiotropic Antidepressive Effects of Cardiovascular Disease Risk Factor Interventions in the Metabolic Syndrome. J Am Heart Assoc. 2018 Mar 26;7(7). pii: e008185. DOI: 10.1161/JAHA.117.008185. PMID: 29581223.
    36. Goebel EA, Ettler HC, Walsh JC. Intradepartmental consultations in surgical pathology: Review of a standardized process and factors influencing consultation rates and practices in an academic and community hospital setting. Pathology - Research and Practice, Volume 214, Issue 4,2018, Pages 542-546, ISSN 0344-0338, https://doi.org/10.1016/j.prp.2018.02.009.
    37. Goebel EA, Stegmaier M, Gorassini DR, Kubica M, Parfitt JR, Driman DK. Grading of Total Mesorectal Excision Specimens: Assessment of Interrater Agreement. Dis Colon Rectum. 2018 Jun;61(6):686-691. DOI: 10.1097/DCR.0000000000000994. PMID: 29722727.
    38. Goebel EA, McLachlin CM, Ettler HC, Weir MM.  Insufficient and Scant Endometrial Samples: Determining Clinicopathologic Outcomes and Consistency in Reporting.  Int J Gynecol Pathol. 2018 May 10. DOI: 10.1097/PGP.0000000000000514. [Epub ahead of print]  PMID: 29750710
    39. Gomes J, Lucien F, Cooper TT, Kim Y, Williams KC, Liao X, Kaufman L, Lagugné-Labarthet F, Kenyon O, Boysen J, Kay NE, McIntyre CW, Leong HS. Analytical Considerations in Nanoscale Flow Cytometry of Extracellular Vesicles to Achieve Data Linearity. Thromb Haemost. 2018 Sep;118(9):1612-1624. DOI: 10.1055/s-0038-1668544. Epub 2018 Aug 15. PMID: 30112749 DOI:10.1055/s-0038-1668544
    40. Gordon AD, Biswas S, Feng B, Chakrabarti S. MALAT1: A regulator of inflammatory cytokines in diabetic complications. Endocrinol Diabetes Metab. Jan 2018; e00010. DOI:10.1002/edm2.10.
    41. Harricharan S, Biederman K, Bombassaro AM, Lazo-Langner A, Elsayed S, Fulford A, Delport JA, and Xenocostas A. Adherence and Outcomes of a Galactomannan Screening Protocol in High Risk Hematology Patients. Curr Oncol. 2018 Apr;25(2):e139-e145. DOI: 10.3747/co.25.3848. Epub 2018 Apr 30. PMID: 29719438.
    42. Ikeda KM, Aldosari MM, Mirsattari SM, AlGhefari H, Hammond RR.  Focal Cortical Dysplasia Type IIa Manifesting as Epilepsia Partialis Continua for 50 Years.  Can J Neurol Sci. 2018 Jan;45(1):106-108. DOI: 10.1017/cjn.2017.237. Epub 2017 Oct 2.  PMID: 28965498
    43. Ishak CA, Cecchini MJ, Howlett CJ, Dick FA. Immunohistochemical Detection of the Retinoblastoma Protein. Methods Mol Biol, 2018 Jan 1; 1726: 65-75. DOI: 10.1007/978-1-4939-7565-5_7. PMID: 29468544.
    44. Kalia V, Daher O, Garvin G, Chhibber S, Shepherd J.  Synchronous bilateral lipoma arborescens of bicipitoradial bursa-a rare entity.  Skeletal Radiol. 2018 Mar 2. DOI: 10.1007/s00256-018-2915-7. [Epub ahead of print]  PMID: 29500484
    45. Karapetyan V, Staudt MD, McGregor SM, BAlYamany, Haji FA, Ang LC, Siddiqi F.  P.143 Spinal cord intramedullary malignant peripheral nerve sheath tumour: case report and review of literature.  Canadian Journal of Neurological Sciences. Volume 45, June 2018, p. S54
    46. Kim SS, Nikoloudaki G, Darling M, Rieder MJ, Hamilton DW. Phenytoin activates Smad3 phosphorylation and periostin expression in drug-induced gingival enlargement. Histol Histopathol. 2018 Jun 19:18015. DOI: 10.14670/HH-18-015. [Epub ahead of print] PMID: 29916554.
    47. Kolendowski B, Hassan H, Krstic M, Isovic M, Thillainadesan G, Chambers AF, Tuck AB, Torchia J. Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization. Epigenetics Chromatin. 2018 Jan 29;11(1):5. DOI: 10.1186/s13072-018-0176-2. PMID: 29378668.
    48. Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA; Hereditary Ovarian Cancer Clinical Study Group. Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation. Gynecol Oncol. 2018 May 21. pii: S0090-8258(18)30898-9. DOI: 10.1016/j.ygyno.2018.05.011. [Epub ahead of print]. PMID: 2979380.
    49. Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2018 May 17. DOI: 10.1007/s10549-018-4822-y. [Epub ahead of print]. PMID: 29774471.
    50. Langdon KD, Krivosheya D, Hebb MO, Wehrli B and Ang LC.  Extracranial invasion of a recurrent, transformed anaplastic pleomorphic xanthoastrocytoma: a case report.  Volume 45, Supplement S1 (ABSTRACTS: 57th Annual Canadian Association of Neuropathologists Meeting) May 2018, pp.S2-S3
    51. Lebo MS, Zakoor K-R, Chun K, Speevak MD, Waye JS, McCready E, Parboosingh JS, Lamont RE, Feilotter H, Bosdet I, Tucker T, Young S, Karsan A, Charames GS, Agatep R, Spriggs EL, Chisholm C, Vasli N, Daoud H, Jarinova O, Tomaszewski R, Hume S, Taylor S, Akbari MR, Lerner-Ellis J, Ainsworth P, Aronson M, Basran R, Blavier A, Blumenthal A, Boycott K, Brudno M, Buckley K, Campbell J, Campeau PM, Care M, Carson N, Carter R, Chitayat D, Chong G, Chouinard E, Craddock KJ, Docking R, Eisen A, Faghfoury H, Farrell S, Fernandez B, Fiume M, Forster-Gibson C, Friedman J, Foulkes W, Goodhand P, Gu J, Hegele R, Holter S, Horsburgh S, Hughes L, Jewett F, Junker A, Khalouei S, Knoll J, Kolomeitz E, Knoppers B, Maire G, Marshall C, Mitchell G, Moorhouse MJ, Morel C, Nelson T, Noor A, O'Connor B, O'Rielly D, Ouellette F, Racher H, Ray P, Rehm H, Riddell C, Riviere, J-B, Rosenblatt DS, Rouleau G, Ruchon A, Sabatini P, Sadikovic B, Semotiuk K, Scherer SW, Shuman C, Silver J, Siminovitch K, Solomon-Izsak L, Soucy J-F, Stavropoulos J, Stein L, Tannenbaum R, Terespolsky D, Wintle RF, Wong B, Wong N, Wang M, Watkins N, White S, Woods MO, Wyatt P, Canadian Open Genetics Repository Working Group17. Data sharing as a national quality improvement program: Reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR). (2018) Genetics in Medicine, 20 (3), pp. 294-302. DOI: 10.1038/gim.2017.80.
    52. Lebo MS, Zakoor K-R, Chun K, Speevak MD, Waye JS, McCready E, Parboosingh JS, Lamont RE, Feilotter H, Bosdet I, Tucker T, Young S, Karsan A, Charames GS, Agatep R, Spriggs EL, Chisholm C, Vasli N, Daoud H, Jarinova O, Tomaszewski R, Hume S, Taylor S, Akbari MR, Lerner-Ellis J, Ainsworth P, et. al. Canadian Open Genetics Repository Working Group17.  Data sharing as a national quality improvement program: Reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR).  Genet Med. 2018 Mar;20(3):294-302. DOI: 10.1038/gim.2017.80. Epub 2017 Jul 20.  PMID: 28726806
    53. Lee JY, Ismail OZ, Zhang X, Haig A, Lian D, Gunaratnam L. Donor kidney injury molecule-1 promotes graft recovery by regulating systemic necroinflammation. Am J Transplant. 2018 Mar 30. DOI: 10.1111/ajt.14745. [Epub ahead of print]. PMID: 29603641.
    54. Lin S, Lian D, Liu W, Haig A, Lobb I, Hijazi A, Razvi H, Burton J, Whiteman M, Sener A. Daily therapy with a slow-releasing H2S donor GYY4137 enables early functional recovery and ameliorates renal injury associated with urinary obstruction. Nitric Oxide. 2018 Mar 6;76:16-28. DOI: 10.1016/j.niox.2018.03.002. [Epub ahead of print]. PMID: 29522906.
    55. Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Cancer Genome Atlas Research Network., Thorsson V, Bass AJ, Laird PW.  Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas (Parfitt, J).  Cancer Cell. 2018 Apr 9;33(4):721-735.e8. DOI: 10.1016/j.ccell.2018.03.010. Epub 2018 Apr 2.  PMID: 29622466
    56. MacLean Scott E, Solomon LA, Davidson C, Storie J, Palikhe NS, Cameron L.  Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism.  PLoS One. 2018 Jul 3;13(7):e0199156. DOI: 10.1371/journal.pone.0199156. eCollection 2018.  PMID: 29969451
    57. Mataseje LF, Boyd DA, Fuller J, Haldane D, Hoang L, Lefebvre B, Melano RG, Poutanen S, Van Caeseele P, Mulvey MR. Characterization of OXA-48-like carbapenemase producers in Canada, 2011-14. J Antimicrob Chemother. 2017 Dec 18. doi: 10.1093/jac/dkx462. [Epub ahead of print]. PMID: 29272439.
    58. Morrison MD, Jackson-Boeters L, Khan ZA, Shimizu MS, Franklin JH, Fung K, Yoo. JHJ, Darling MR. Identifying Candidate Biomarkers for Pleomorphic Adenoma: A Case-Control Study. Head Neck Pathol. 2018 Aug 17. DOI: 10.1007/s12105-018-0959-6. [Epub ahead of print] PubMed PMID: 30120721.
    59. Osmond A, Ashok D, Francoeur CA, Miller M, Walsh JC. Is focal active colitis of greater clinical significance in pediatric patients? A retrospective review of 68 cases with clinical correlation. Hum Pathol, 2018 Jan 20. DOI: 10.1016/j.humpath.2018.01.012. PMID: 29360496.
    60. Pacheco I, Buzea C. Nanoparticle uptake by plants – beneficial or detrimental?, invited book chapter in Phytotoxicity of nanoparticles, Editors: M. Faisal, Q. Saquib, A. A. Alatar, A.z A. Al-Khedhairy, Springer Science & Business Media, 2018.
    61. Plouffe RA, Hammond R, Goldberg HA, Chahine S. What Matters from Admissions? Identifying Success and Risk Among Canadian Dental Students.  J Dent Educ. 2018 May;82(5):515-523. DOI: 10.21815/JDE.018.057.  PMID: 29717076
    62. Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Gu S, Fong C, Tuck A, Youngson B, Miller N, Done SJ, Chang MC, Sengupta S, Elavathil L, Jani PA, Bonin M, Lalani N, Paszat L. Omitting radiation therapy after lumpectomy for pure DCIS does not reduce the risk of salvage mastectomy. Breast. 2018 Feb;37:181-186. DOI: 10.1016/j.breast.2017.07.002. Epub 2017 Aug 3. PMID: 28781102.
    63. Remington L, Isaacs A, Vickers D, Fuller J, and Smith S. Epidemiology of candidemia at a tertiary Canadian hospital 2004-2013. J. Assoc Med Microbiol Infect Dis. 2018 March 12;3.1:14-23.
    64. Ruicci KM, Meens J, Sun RX, Rizzo G, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Boutros PC, Ailles L, Nichols AC. A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Ka inhibition in controlling tumor growth. Int J Cancer. 2018 Nov 23. DOI: 10.1002/ijc.32009. [Epub ahead of print] PMID: 30468243
    65. Rutledge AB, McLeod N, Mehan N, Regan TW, Ainsworth P, Chong P, Doyle T, White M, Sanson-Fisher RW, Martin JM. A clinician-centred program for behaviour change in the optimal use of staging investigations for newly diagnosed prostate cancer. BJU Int. 2018 May;121 Suppl 3:22-27. DOI: 10.1111/bju.14144. Epub 2018 Feb 16.  PMID: 29359883.
    66. Schenkel LC, Aref-Eshghi E, Skinner C, Ainsworth P, Lin H, Paré G, Rodenhiser DI, Schwartz C, Sadikovic B. Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C. Clin Epigenetics. 2018 Feb 14;10:21. DOI: 10.1186/s13148-018-0453-8. eCollection 2018. PMID: 29456765.
    67. Silva PN, Chang HH, Arany EJ, Shukalyuk AI, Audet J, Kilkenny DM, Rocheleau JV. Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation. J Biol Chem. 2018 Sep 14. pii: jbc.RA118.003036. DOI: 10.1074/jbc.RA118.003036. [Epub ahead of print] PMID: 30217817
    68. Singh SS, Pilkerton CS, Shrader CD Jr, Frisbee SJ. Subclinical atherosclerosis, cardiovascular health, and disease risk: is there a case for the Cardiovascular Health Index in the primary prevention population?  BMC Public Health. 2018 Apr 2;18(1):429. DOI: 10.1186/s12889-018-5263-6. PMID: 29609588.
    69. Solh Z, Brouwers M, Florez ID. Knowledge translation in transfusion medicine. Part 1: The basics and the frameworks. Transfusion. 2018 Jan 30. DOI: 10.1111/trf.14487. [Epub ahead of print]. PMID: 29383724.
    70. Solh Z, Brouwers M, Florez ID. Knowledge translation in transfusion medicine. Part 3: Interventions and tools. Transfusion. 2018 Apr 17. DOI: 10.1111/trf.14653. [Epub ahead of print]. PMID: 29667202.
    71. Sullivan R, McGirr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L, Dhanvantari S.  Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice.  J Endocr Soc. 2017 Dec 28;2(2):178-189. DOI: 10.1210/js.2017-00433. eCollection 2018 Feb 1.  PMID: 29450407
    72. Tarnopolsky MA, Sundaram ANE, Provias J, Brady L, Sadikovic B. CPEO - Like mitochondrial myopathy associated with m.8340G>A mutation. Mitochondrion. 2018 Mar 6. pii: S1567-7249(17)30331-8. DOI:10.1016/j.mito.2018.02.008. [Epub ahead of print]. PMID: 29501485.
    73. Taylor R, Alyamany B, Pandey S, Kertesz A, Ang LC, Finger E.  Two Distinct Clinical Phenotypes in a Family with ALSP Caused by a Novel CSF-1R Mutation. (P2.176)  Neurology April 10, 2018; 90 (15 Supplement)
    74. Thomas AA, Feng B, Chakrabarti S. ANRIL regulates production of extracellular matrix proteins and vasoactive factors in diabetic complications. Am J Physiol Endocrinol Metab. 2018 Mar 1;314(3):E191-E200. DOI: 10.1152/ajpendo.00268.2017. Epub 2017 Nov 7. PMID: 29118015
    75. Tong J, Fitzmaurice PS, Moszczynska A, Rathitharan G, Ang LC, Meyer JH, Mizrahi R, Boileau I, Furukawa Y, McCluskey T, Sailasuta N, Kish SJ. Normal glutathione levels in autopsied brain of chronic users of heroin and of cocaine.  Drug Alcohol Depend. 2018 Jun 23;190:20-28. DOI: 10.1016/j.drugalcdep.2018.05.021. [Epub ahead of print]  PMID: 29960919
    76. Tsoi VK, Bhayana V, Bombassaro AM, Tirona R, Betchen D, Kittanakom S. Falsely Elevated Vancomycin Concentrations in a Patient Not Receiving Vancomycin. Canadian Journal of Hospital Pharmacy; 2018. p. 58.
    77. Walsh JC, Padgett J, Weir MM, et al.  Comparing Perceptions of Pathology as a Medical Specialty between Canadian Pathologists and Pre-clinical Medical Students.  Med.Sci.Educ. (2018). DOI: 10.1007/s40670-018-0596-4
    78. Warners MJ, Ambarus CA, Bredenoord AJ, Verheij J, Lauwers GY, Walsh JC, Katzka DA, Nelson S, van Viegen T, Furuta GT, Gupta SK, Stitt L, Zou G, Parker CE, Shackelton LM, D Haens GR, Sandborn WJ, Dellon ES, Feagan BG, Collins MH, Jairath V, Pai RK. Reliability of Histologic Assessment in Patients with Eosinophilic Oesophagitis. PMID: 29460418.
    79. Webster-Clark M, Jaeger B, Zhong Y, Filler G, Alvarez-Elias A, Franceschini N, Díaz-González de Ferris ME.  Low agreement between modified-Schwartz and CKD-EPI eGFR in young adults: a retrospectivelongitudinal cohort study.  BMC Nephrol. 2018 Aug 6;19(1):194. DOI: 10.1186/s12882-018-0995-1.  PMID: 30081844
    80. Yousef PG, Gabril MY. An update on the molecular pathology of urinary bladder tumors.Pathol Res Pract. 2018 Jan;214(1):1-6. DOI: 10.1016/j.prp.2017.11.003. Epub 2017 Nov 10. PMID: 29254798.
    81. Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. An aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation. Neuropathol Appl Neurobiol. Letter. 2018 Feb;44(2):240-243. DOI: 10.1111/nan.12404. PMID: 28403515.
    82. Zhao X, Sehgal M, Hou ZF, Cheng JJ, Shu SN, Wu S, Guo F, Le Marchand SJ, Lin HX, Chang J, and Guo JT. Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses. Journal of Virology, 2018, Feb 26;92(6). DOI: 10.1128/JVI.01535-17. PMID:29263263.
    83. Zhou H and Fuller J. Recurrent Echinocandin-resistant Candida glabrata candidemia following prolonged micafungin treatment for multiple intra-abdominal abscesses: A case report. J. Assoc Med Microbiol Infect Dis. 2018 Apr 17;3.1:52-55.
    84. Zhuge W, Chen R, Guo G, Dong X, Khan Z, Sun X, Dai X, Chen X, Bao M, Shen X, Liang G. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer. Cancer Lett. 2018 Jan 1;412:46-58. DOI: 10.1016/j.canlet.2017.10.006. Epub 2017 Oct 13. PMID: 29037867.

2017 Publications

    1. Abbott JA, Guth E, Kim C, Regan C, Siu VM, C. Rupar CA, Demeler B, Francklyn CS, Robey-Bond SM. The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity. Biochemistry. 2017 Jul 18;56(28):3619-3631. doi: 10.1021/acs.biochem.7b00114. Epub 2017 Jul 7. PMID: 28632987.
    2. Abulizi P, Loganathan N, Zhao D, Mele T, Zhang Y, Zwiep T, Liu K, Zheng X. Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide. Sci Rep. 2017 Apr 21;7(1):1037. doi: 10.1038/s41598-017-00902-5. PMID: 28432312.
    3. Alturkustani M, Ang LC, Ramsay D. Pathology of toxic leucoencephalopathy in drug abuse supports hypoxic-ischemic pathophysiology/etiology. Neuropathology. 2017 Mar 9. doi: 10.1111/neup.12377. [Epub ahead of print] PMID: 28276094.
    4. Alvarez-Elías AC, Yoo EC, Todorova EK, Singh RN, Filler G. A Retrospective Study on Mycophenolic Acid Drug Interactions: Effect of Prednisone, Sirolimus, and Tacrolimus With MPA.  The Drug Monit 2017/06/01 .  39 (3) p220-228.  doi: 10.1097/FTD.0000000000000403 / PMID 28437284.
    5. Anderson PT, Gottheil S, Gabril M, Barra L, Power N. Acute urinary retention secondary to urethral involvement of granulomatosis with polyangiitis. Can Urol Assoc J. 2017 Jan-Feb;11(1-2):E38-E40. doi: 10.5489/cuaj.3555. Epub 2017 Jan 12. PMID: 28163812.
    6. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Siu V, Rodenhiser D, Schwartz C, Sadikovic B. Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders. J Mol Diagn, 2017 Aug 11, Senior Responsible Author, DOI: 10.1016/j.jmoldx.2017.07.002. PMID 28807811.
    7. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B. The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance. Epigenetics. 2017 Sep 21:0. doi: 10.1080/15592294.2017.1381807. [Epub ahead of print]. PMID 28933623.
    8. Balci TB, Hartley T, Xi Y, Dyment DA, Beaulieu CL, Bernier FP, Dupuis L, Horvath GA, Mendoza-Londono R, Prasad C, Richer J, Yang XR, Armour CM, Bareke E, Fernandez BA, McMillan HJ, Lamont RE, Majewski J, Parboosingh JS, Prasad AN, Rupar CA, Schwartzentruber J, Smith AC, Tétreault M; FORGE Canada Consortium; Care4Rare Canada Consortium, Innes AM, Boycott KM. Debunking Occam’s razor: Diagnosing multiple genetic diseases in families by whole exome sequencing. Clin Genet. 2017 Sep;92(3):281-289. doi: 10.1111/cge.12987. Epub 2017 Mar 13. PMID: 28170084.
    9. Banaschewski BJH, Baer B, Arsenault C, Jazey T, Veldhuizen EJA, Delport J, Gooyers T, Lewis JF, Haagsman HP, Veldhuizen RAW, Yamashita C. The Antibacterial and Anti-inflammatory Activity of Chicken Cathelicidin-2 combined with Exogenous Surfactant for the Treatment of Cystic Fibrosis-Associated Pathogens. Sci Rep. 2017 Nov 14;7(1):15545. doi: 10.1038/s41598-017-15558-4. PMID: 29138462.
    10. Barton M, McKelvie B, Campigotto A, Mullowney T. Legionellosis following water birth in a hot tub in a Canadian neonate. CMAJ. 2017 Oct 23;189(42):E1311-E1313. doi: 10.1503/cmaj.170711. PMID: 29061856
    11. Beamish CA, Mehta S, Strutt BJ, Chakrabarti S, Hara M, Hill DJ. Decrease in Ins+Glut2LO ß-cells with advancing age in mouse and human pancreas. J Endocrinol. 2017 Jun;233(3):229-241. doi: 10.1530/JOE-16-0475. Epub 2017 Mar 27. PMID: 28348115
    12. Biwas S, Chakrabarti S. Pathogenetic Mechanisms in Diabetic Retinopathy: From Molecules to Cells to Tissues. In: Kartha CC, Ramachandran S, Pillai R, editor(s). Mechanisms of Vascular Defects in Diabetes Mellitus. Springer; 2017. p.209-247. Book Chapter.
    13. Blake A, Dragan M, Tirona RG, Hardy DB, Brackstone M, Tuck AB, Babwah AV, Bhattacharya M. G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance. Sci Rep. 2017 Apr 19;7:46525. doi: 10.1038/srep46525. PMID: 28422142.
    14. Bone KM, Chernos J, Perrier R, Innes AM, Bernier FP, McLeod R, Thomas MA. Mosaic trisomy 1q: a recurring chromosome anomaly that is a diagnostic challenge and is associated with a Fryns-like phenotype. Prenatal Diagnosis. 2017 Apr 24. DOI: 10.1002/pd.5058. [Epub ahead of print] PMID: 28437579.
    15. Boyd DA, Mataseje LF, Davidson R, Delport JA, Fuller J, Hoang L, Lefebvre B, Levett P, Roscoe DL, Willey BM, Mulvey MR. Enterobacter cloacae complex isolates harboring blaNMC-A or blaIMI-type class A carbapenemase genes on novel chromosomal integrative elements and plasmids.Antimicrob Agents Chemother. 2017 Feb 21: 61(5). pii: AAC.02578-16. doi: 10.1128/AAC.02578-16. [Epub ahead of print]. PMID: 28223374.
    16. Brackstone M, Palma D, Tuck AB, Scott L, Potvin K, Vandenberg T, Perera F, D'Souza D, Taves D, Kornecki A5, Muscedere G, Chambers AF. Concurrent Neoadjuvant Chemotherapy and Radiation Therapy in Locally Advanced Breast Cancer. Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):769-776. doi: 10.1016/j.ijrobp.2017.06.005. Epub 2017 Jun 20. PMID: 28870785
    17. Brewer-Deluce D, Gibson CJ. Teaching Matters: Developing Teaching Dossiers to Showcase Teaching Success and Competency. Teaching Innovation Projects: Vol. 7: Iss. 1 Article 1, 2017. Available at: http://ir.lib.uwo.ca/tips/vol7/iss1/1
    18. Budhram A, Leung A, Sangle N, Khaw AV. Diffuse Large B-Cell Lymphoma of the Nasopharynx Presenting With Cluster-Like Headache. Headache. 2017 Mar 13. doi: 10.1111/head.13065. [Epub ahead of print]. PMID: 28295284.
    19. Budhram A, Gabril MY, Lee DH, Fraser JA. Hypertrophic Pachymeningitis With Optic Neuropathy Heralding Systemic Vasculitis. Can J Neurol Sci. 2017 Jan;44(1):105-107. doi: 10.1017/cjn.2016.51. Epub 2016 May 17. PMID: 27184909.
    20. Buzea C, Pacheco I. (2017) Nanomaterials and their classification. In: EMR/ESR/EPR spectroscopy for characterization of nanomaterials. Springer Book Series: Advance Structured Materials, ISBN 978-81-322-3653-5 ISBN 978-81-322-3655-9. http://www.springer.com/la/book/9788132236535.
    21. Cecchini MJ, Walsh JC, Parfitt J, Chakrabarti S, Correa R, MacKenzie MJ, Driman DK . The Utility of CDX2 loss as a prognostic marker in state II colon cancer.   2017/07/01.
    22. Chen BB, Prasad C, Walsh JC, Ashok D. Eight-year-old girl with hepatomegaly. Paediatr Child Health (2017) 22 (3): 115-116.  DOI: https://doi.org/10.1093/pch/pxx036 .
    23. Chen S, Feng B, Thomas AA, Chakrabarti S. miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes. PLoS One. 2017 Mar 16;12(3):e0173918. doi: 10.1371/journal.pone.0173918. eCollection 2017. PMID 28301595.
    24. Chin-Yee B, Lazo-Langner A, Butler-Foster T, Hsia C, Chin-Yee I. Blood donation and testosterone replacement therapy.  Transfusion 2017/03/01: 57 (3) p578-581.  doi: 10.1111/trf.13970 / PMID 28150363.
    25. Darling MR, Woodford R, Cuddy KK, Jackson-Boeters L, Hayter A, Inkaran J, Diamandis EP, Khan Z. Kallikrein-related peptidase expression in odontogenic cysts and tumors: An immunohistochemical comparative study. J Investig Clin Dent. 2017 Jan 4. DOI: 10.1111/jicd.12256. [Epub ahead of print] PMID: 28054463.
    26. Darling MR, Su N, Masen S, Kwon P, Fortino D, McKerlie T, Grushka M. Geographic tongue: assessment of peripheral nerve status, Langerhans cell, and HLA-DR expression. Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Oct; 124(4):371-377. PMID: 28757081.
    27. Das S, Ang LC, Ramsay D. Intrasellar cavernous hemangioma presenting as pituitary adenoma: A report of two cases and review of the literature. Clin Neuropathol. 2017 Nov 30. doi: 10.5414/NP301012. [Epub ahead of print].  PMID: 29189199.
    28. Das S, Chaudhary N, Ang LC, Megyesi JS. Papillary thyroid carcinoma metastasizing to anaplastic meningioma: an unusual case of tumor-to-tumor metastasis. Brain Tumor Pathol. 2017 Jun 9. doi: 10.1007/s10014-017-0289-5. [Epub ahead of print] PMID: 28600666.
    29. Delport JA, Strikwerda A, Armstrong A, Schaus D, John M. MALDI-ToF short incubation identification from blood cultures is associated with reduced length of hospitalization and a decrease in bacteremia associated mortality. Eur J Clin Microbiol Infect Dis. 2017 Jan 20:1-6. DOI: 10.1007/s10096-017-2906-y. [Epub ahead of print] PMID: 28108794.
    30. Driman D, Schick B. Image editing for pathologists. Histopathology 2017, 70, 840–841. DOI: 10.1111/his.13146. PMID: 28297121.
    31. Fazio EN, Young CC, Toma J, Levy M, Berger KR, Johnson CL, Mehmood R, Swan P, Chu A, Cregan SP, Dilworth FJ, Howlett CJ, Pin CL. Activating Transcription Factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice. Mol Biol Cell, 2017 Jul 12, Coauthor, DOI: 10.1091/mbc.E17-04-0254. PMID 28701342.
    32. Farhan SMK, Nixon KCJ, Everest M, Edwards TN, Long S, Segal D, Knip MJ, Arts HH, Chakrabarti R, Wang J, Robinson JF, Lee D, Mirsattari SM, Rupar CA, Siu VM; FORGE Canada Consortium, Poulter MO, Hegele RA, Kramer JM. Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy. Hum Mol Genet. 2017 Nov 1;26(21):4278-4289. doi: 10.1093/hmg/ddx316. PMID: 28973161.
    33. Feng B, Chen S, Gordon AD, Chakrabarti S. miR-146a mediates inflammatory changes and fibrosis in the heart in diabetes. J Mol Cell Cardiol. 2017 Apr;105:70-76. doi: 10.1016/j.yjmcc.2017.03.002. Epub 2017 Mar 6. PMID: 28279663.
    34. Filek R, Hooper P, Sheidow T, Gonder J, Varma DK, Heckler L, Hodge W, Chakrabarti S, Hutnik CML. Structural and functional changes to the retina and optic nerve following panretinal photocoagulation over a 2-year time period. Eye (Lond). 2017 Apr 28. doi: 10.1038/eye.2017.66. [Epub ahead of print]. PMID: 28452993.
    35. Filler G , Kobrzynski M, Sidhu HK, Belostotsky V, Huang SHS, McIntyre C, Yang L. A cross-sectional study measuring vanadium and chromium levels in paediatric patients with CKD. BMJ Open 2017;0:e014821. doi:10.1136/bmjopen-2016-014821. PMID 28592575.
    36. Filler G, Alvarez-Elías AC, McIntyre C, Medeiros M. The compelling case for therapeutic drug monitoring of mycophenolate mofetil therapy.  Pediatr Nephrol 2017/01/01: 32 (1) p21-29.  doi: 10.1007/s00467-016-3352-2 / PMID 26921212.
    37. Filler G, Belostotsky V, Kobrzynski M, Huang SS, Yang L. High prevalence of elevated molybdenum levels in pediatric CKD patients. A cross-sectional and longitudinal study.  Clin Nephrol 2017/08/01: 88 (8) p79-85.  doi: 10.5414/CN109015 / PMID 28502322.
    38. Filler G, Ferris M. We have to do more for former paediatric renal transplant recipients!  Transpl Int 2017/09/02:  doi: 10.1111/tri.13058 / PMID 28865119.
    39. Filler G, Huang SS. Spot urine protein to creatinine ratio.  Pediatr Nephrol 2017/02/14:  doi: 10.1007/s00467-017-3605-8 / PMID 28197886.
    40. Filler G, Kobrzynski M, Sidhu HK, Belostotsky V, Huang SHS, McIntyre C, Yang L. A cross-sectional study measuring vanadium and chromium levels in paediatric patients with CKD.  BMJ Open 2017; 7(5) :e014821. doi:10.1136/bmjopen-2016-014821. PMID 28592575.
    41. Filler G, Lee M, Hegele RA. Barriers to the Implementation of Lipoprotein Apheresis in Canada.  Can J Cardiol 2017/03/01: 33 (3) p409-411.  doi: 10.1016/j.cjca.2017.01.008 / PMID 28232020.
    42. Filler G, Licht C, Huang SS. Is there a case for eculizumab for pediatric renal transplantation? Pediatr Transplant. 2018 Feb 7. doi: 10.1111/petr.13128. [Epub ahead of print]. PMID: 29417722.
    43. Filler G, Medeiros M. Improving long-term outcomes after pediatric renal transplantation by addressing dyslipidemia.  Pediatr Transplant 2017/05/01: 21 (3) doi: 10.1111/petr.12880 / PMID 28370889.
    44. Filter ER, Gabril MY, Gomez JA, Wang PZT, Chin JL, Isawa J, Moussa M. Incidental Prostate Adenocarcinoma in Cystoprostatectomy Specimens: Partial Versus Complete Prostate Sampling. International Journal of Surgical Pathology. Article first published online: March 22, 2017. DOI: 10.1177/1066896917696745.
    45. Florendo-Cumbermack A, Selchen D, Morrow SA, Sharma M, Steven D, Ang LC, Casserly C, Burneo J, Kremenchutzky M, Hammond R.   Everything Old is New Again.  Can J Neuro Sci.  Volume 43, Issue 1, 5 Jan 2016, Pages 213-218  DOI:  10.1017/cjn.2015.309
    46. Fonseka TM, McKinley GP, Kennedy SH. Is tetraethyl lead poison affecting contemporary indigenous suicides in Ontario, Canada? Psychiatry Res. 2017 Jan 7; 251:253-254. DOI: 10.1016/j.psychres.2017.01.003. [Epub ahead of print] PMID: 28219024.
    47. Fujii S, Tugaleva E, Chu MWA, Bainbridge D. A Curious Case of Blood Culture Negative Infective Endocarditis. Journal of Cardiothoracic and Vascular Anesthesia. 2017, ISSN 1053-0770, http://dx.doi.org/10.1053/j.jvca.2017.04.031 . ( http://www.sciencedirect.com/science/article/pii/S1053077017304238 ).
    48. Gatanaga H, Brumme ZL, Adland E, Reyes-Terán G, Avila-Rios S, Mejía-Villatoro CR, Hayashida T, Chikata T, Van Tran G, Van Nguyen K, Meza RI, Palou EY, Valenzuela-Ponce H, Pascale JM, Porras-Cortés G, Manzanero M, Lee GQ, Martin JN, Carrington MN, John M, Mallal S, Poon AFY, Goulder P, Takiguchi M, Oka S; International HIV Adaptation Collaborative. Potential for immune-driven viral polymorphisms to compromise antiretroviral-based pre-exposure prophylaxis for prevention of HIV-1 infection. AIDS. 2017 Jun 23. doi: 10.1097/QAD.0000000000001575. [Epub ahead of print. PMID: 28650381.
    49. Gibson RM, Nickel G, Crawford M, Kyeyune F, Venner C, Nankya I, Nabulime E, Ndashimye E, Poon AFY, Salata RA, Kityo C, Mugyenyi P, Quiñones-Mateu ME, Arts EJ. Sensitive detection of HIV-1 resistance to Zidovudine and impact on treatment outcomes in low- to middle-income countries. Infect Dis Poverty. 2017 Dec 4;6(1):163. doi: 10.1186/s40249-017-0377-0.  PMID:29202874.
    50. Haig A . A novel approach to off-clamp partial nephrectomy demonstrates significant improvement in renal injury in an experimental porcine model.  Canadian Urological Association Journal 2017/10/01.  
    51. Hosseini-Moghaddam, Xu Q, Kum J, Alharbi H, Jevnikar A, John M, Singh G, Parsons S, Edgar M, Luke Risk Factors for Polyomavirus After Renal Transplantation: Introduction of the Protective Effect of Peritoneal Dialysis . 2017/04/29.
    52. Huang J, Khan A, Au BC, Barber DL, López-Vásquez L, Prokopishyn NL, Boutin M, Rothe M, Rip JW, Abaoui M, Nagree MS, Dworski S, Schambach A, Keating A, West ML, Klassen J, Turner PV, Sirrs S, Rupar CA, Auray-Blais C, Foley R, Medin JA. Lentivector Iterations and Pre-Clinical Scale-up/Toxicity Testing: Targeting Patient Mobilized CD34+ Hematopoietic Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017 May 12;5:241-258. doi: 10.1016/j.omtm.2017.05.003. eCollection 2017 Jun 16. PMID: 28603745.
    53. Huynh M, Clark R, Li J, Filler G, Dave S. A case control analysis investigating risk factors and outcomes for nephrocalcinosis and renal calculi in neonates.  J Pediatr Urol 2017/07/27:  doi: 10.1016/j.jpurol.2017.06.018 / PMID 28821388.
    54. Ioanidis KE, MacNeil SD, Tay KY, Wehrli B. An atypical lipomatous tumor mimicking a giant fibrovascular polyp of the hypopharynx: A case report. Medicine (Baltimore). 2017 Oct;96(43):e6927. doi: 10.1097/MD.0000000000006927. PMID: 29068974.
    55. Ismail OZ, Bhayana V, Kadour M, Lepage N, Gowrishankar M, Filler G. Improving the translation of novel biomarkers to clinical practice: The story of cystatin C implementation in Canada: A professional practice column. Clin Biochem. 2017 May;50 (7-8):380-384. doi: 10.1016/j.clinbiochem.2017.01.005. Epub 2017 Jan 11. PMID: 28088453.
    56. Ismail OZ, Bhayana V.  Lipase or amylase for the diagnosis of acute pancreatitis? Clin Biochem. 2017 Jul 16. pii: S0009-9120(17)30356-9. doi: 10.1016/j.clinbiochem.2017.07.003. [Epub ahead of print]. PMID 2872034.
    57. Joy TR, McKenzie CA, Tirona RG, Summers K, Seney S, Chakrabarti S, Malhotra N, Beaton MD. Sitagliptin in patients with non-alcoholic steatohepatitis: A randomized, placebo-controlled trial. World J Gastroenterol. 2017 Jan 7;23(1):141-150. doi: 10.3748/wjg.v23.i1.141. PMID 28104990.
    58. Kakar S, Shi C, Berho ME, Driman DK, Fitzgibbons P, Frankel WL, Hill KA, Jessup J, Krasinskas AM, Washington MK.  College of American Pathologists Protocol for the Examination of Specimens From Patients With Primary Carcinoma of the Colon and Rectum, v4. 8th edition AJCC, 2017.
    59. Kakar S, Shi C, Berho ME, Driman DK, Fitzgibbons P, Frankel WL, Hill KA, Jessup J, Krasinskas AM, Misdraji J, Overman MJK, Pai RK, Washington MK. Protocol for the Examination of Specimens From Patients With Carcinoma of the Appendix, v4. 8th edition AJCC, 2017.
    60. Kakar S, Shi C, Berho ME, Driman DK, Fitzgibbons P, Frankel WL, Hill KA, Jessup J, Krasinskas AM, Washington MK. Protocol for the Examination of Specimens From Patients With Carcinoma of the Anus. 2017, v4. 8th edition AJCC, 2017.
    61. Keeney M, Hedley BD, Chin-Yee IH. Flow cytometry-Recognizing unusual populations in leukemia and lymphoma diagnosis.  Int J Lab Hematol 2017/05/01: 39 Suppl 1 p86-92.  doi: 10.1111/ijlh.12666 / PMID 28447408.
    62. Kerkhof J, Schenkel LC, Reilly J, McRobbie S, Aref-Eshghi E, Stuart A, Rupar CA, Adams P, Hegele RA, Lin H, Rodenhiser D, Knoll J, Ainsworth PJ, Sadikovic B. Clinical Validation of Copy Number Variant Detection from Targeted Next-Generation Sequencing Panels. J Mol Diagn, 2017 Aug 14, Senior Responsible Author, DOI: 10.1016/j.jmoldx.2017.07.004. PMID 28818680.
    63. Kirpalani A, Rieder MJ, Bax KC, Filler G. Idiosyncratic drug reactions and membranous glomerulopathy.  BMJ Case Rep 2017/01/30: 2017 1136/bcr-2016-218496 / PMID 28137906.
    64. Kumar N, Rizek P, Sadikovic B, Adams PC, Jog M.  Movement Disorders Associated With Hemochromatosis.  Can J Neurol Sci. 2016 Nov;43(6):801-808.  DOI:  10.1017/cjn.2016.286  PMID: 27827297
    65. Kwan BYM, Salehi F, Kope R, Lee DH, Sharma M, Hammond R, Burneo JG, Steven D, Peters T, Khan AR. Evaluation of ex-vivo 9.4T MRI in post-surgical specimens from temporal lobe epilepsy patients. J Neuroradiol. 2017 Jul 4. pii: S0150-9861(17)30161-X. doi: 10.1016/j.neurad.2017.05.007. [Epub ahead of print]. PMID: 28687122.
    66. Lackie RE, Maciejewski A, Ostapchenko VG, Marques-Lopes J, Choy WY, Duennwald ML, Prado VF, Prado MAM. The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases. Front Neurosci. 2017 May 16;11:254. doi: 10.3389/fnins.2017.00254. eCollection 2017. PMID 28559789.
    67. Langdon K, Singsnaeh A, Young G, Hammond R. Adult-onset progressive dementia and myoclonic epilepsy with polyglucosan bodies. (2017). Canadian Journal of Neurological Sciences / Journal Canadien Des Sciences Neurologiques,44(S1), S4-S4. doi:10.1017/cjn.2017.11.
    68. Lant JT, Berg MD, Sze DHW, Hoffman KS, Akinpelu IC, Turk MA, Heinemann IU, Duennwald ML, Brandl CJ, O'Donoghue P. Visualizing tRNA-dependent mistranslation in human cells. RNA Biol. 2017 Sep 21:1-9. doi: 10.1080/15476286.2017.1379645. [Epub ahead of print]. PMID: 28933646.
    69. Leach MD, Kim T, DiGregorio SE, Collins C, Zhang Z, Duennwald ML, Cowen LE. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda), 2017 Jan 5; 7 (1): 95-108, DOI: 10.1534/g3.116.035675. PMID: 27807047.
    70. Lebo MS, Zakoor KR, Chun K, Speevak MD, Waye JS, McCready E, Parboosingh JS, Lamont RE, Feilotter H, Bosdet I, Tucker T, Young S, Karsan A, Charames GS, Agatep R, Spriggs EL, Chisholm C, Vasli N, Daoud H, Jarinova O, Tomaszewski R, Hume S, Taylor S, Akbari MR, Lerner-Ellis J, Canadian Open Genetics Repository Working Group. Data sharing as a national quality improvement program: reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR). Genet Med, 2017 Jul 20, Sadikovic B, COGR Working Group Member, DOI: 10.1038/gim.2017.80. PMID 28726806.
    71. Lee M, Barr J, Kribs S, Filler G. Strategies to reduce line infections in a small child with homozygous familial hypercholesterolaemia who cannot yet receive LDL apheresis.  BMJ Case Rep 2017/09/01: 2017 doi: 10.1136/bcr-2017-219538 / PMID 28866629.
    72. Lemieux C, Gardam M, Evans G, John M, Suh KN, vanWalraven C, Vicencio E, Coulby C, Roth V, Hota S. Longitudinal Multicenter Analysis of Outcomes After Cessation of Control Measures for Vancomycin-Resistant Enterococci. Infect Control Hosp Epidemiol. 2017 Jan;38(1):24-30. DOI: 10.1017/ice.2016.235 PMID: 27804901.
    73. Li R, Zhang Y, Zheng X, Peng S, Yuan K, Zhang X, Min W. Synergistic suppression of autoimmune arthritis through concurrent treatment with tolerogenic DC and MSC. Sci Rep. 2017 Feb 23;7:43188. DOI: 10.1038/srep43188. PMID: 28230210.
    74. Liu D, Alvarez-Elías AC, Wile B, Belostotsky V, Filler G. Deviations from the expected relationship between serum FGF23 and other markers in children with CKD: a cross-sectional study.  BMC Nephrol 2017/06/28: 18 (1) p204.  doi: 10.1186/s12882-017-0623-5 / PMID 28659167.
    75. Liu J, Li Y, Wilkins R, Flegal F, Knoll JHM, Rogan PK. Accurate Cytogenetic Biodosimetry Through Automated Dicentric Chromosome Curation And Metaphase Cell Selection.F1000Res. 2017 Aug 9;6:1396. doi: 10.12688/f1000research.12226.1. eCollection 2017. PMID: 29026522.
    76. Lu J, Zheng X, Li F, Yu Y, Chen Z, Liu Z, Wang Z, Xu H, Yang W. Tunneling nanotubes promote intercellular mitochondria transfer followed by increased invasiveness in bladder cancer cells.Oncotarget. 2017 Jan 17. DOI: 10.18632/oncotarget.14695. [Epub ahead of print] PMID: 28107184.
    77. McCloskey RM, Poon AFY. A model-based clustering method to detect infectious disease transmission outbreaks from sequence variation. PLoS Comput Biol. 2017 Nov 13;13(11):e1005868. doi: 10.1371/journal.pcbi.1005868. eCollection 2017 Nov. PMID: 29131825.
    78. McCreery G, Jones PM, Kidane B, DeMelo V, Mele T, and Delport J ERASE C. difficile (Early Rescue from Acute Severe Clostridium difficile) Trials Group 5 .  Polyethylene glycol intestinal lavage in addition to usual antibiotic treatment for severe clostridium difficile colitis: A randomized controlled pilot study.  BMJ 2017/03.
    79. McGee J, Panabaker K, Leonard S, Ainsworth P, Elit L, Shariff SZ. Genetics Consultation Rates Following a Diagnosis of High-Grade Serous Ovarian Carcinoma in the Canadian Province of Ontario. Int J Gynecol Cancer, 2017 Jan 9. DOI: 10.1097/IGC.0000000000000907. PMID: 28072594.
    80. Medeiros M, Lumini J, Stern N, Castañeda-Hernández G, Filler G. Generic immunosuppressants.  Pediatr Nephrol 2017/07/21:  doi: 10.1007/s00467-017-3735-z / PMID 28733752.
    81. Moszczynski AJ, Yang W, Hammond R, Ang LC, Strong MJ. Threonine175, a novel pathological phosphorylation site on tau protein linked to multiple tauopathies. Acta Neuropathol Commun. 2017 Jan 11;5(1):6. doi: 10.1186/s40478-016-0406-4. PMID: 28077166.
    82. Nahlawi L, Goncalves C, Imani F, Gaed M, Gomez JA, Moussa M, Gibson E, Fenster A, Ward AD, Abolmaesumi P, Mousavi P, Shatkay H. Models of temporal enhanced ultrasound data for prostate cancer diagnosis: the impact of time-series order. Proc. SPIE 10135, Medical Imaging 2017: Image-Guided Procedures, Robotic Interventions, and Modeling, 101351D (March 3, 2017) DOI: 10.1117/12.2255798.
    83. Ndosi M, Ferguson R, Backhouse MR, Bearne L, Ainsworth P, Roach A, Dennison E, Cherry L. National variation in the composition of rheumatology multidisciplinary teams: a cross-sectional study. Rheumatol Int. 2017 May 27. doi: 10.1007/s00296-017-3751-0. [Epub ahead of print] PMID: 28551723.
    84. Nothnagel M, Fan G, Guo F, He Y, Hou Y, Hu S, Huang J, Jiang X, Kim W, Kim K, Li C, Li H, Li L, Li S, Li Z, Liang W, Liu C, Lu D, Luo H, Nie S, Shi M, Sun H, Tang J, Wang L, Wang CC, Wang D, Wen SQ, Wu H, Wu W, Xing J, Yan J, Yan S, Yao H, Ye Y, Yun L, Zeng Z, Zha L, Zhang S, Zheng X, Willuweit S, Roewer L. Revisiting the male genetic landscape of China: a multi-center study of almost 38,000 Y-STR haplotypes. Hum Genet. 2017 Jan 30. DOI: 10.1007/s00439-017-1759-x. [Epub ahead of print] Review. PMID: 28138773.
    85. Olvera-Posada D, Lin S, Aboalsamh G, Haig A, Lobb I, Grewal J, Saha MN, Sener A. A novel approach to off-clamp partial nephrectomy demonstrates significant improvements in renal injury in an experimental porcine mode. Journal of the Canadian Urological Association. Volume 11, Issue 10, October 2017, Pages E390-E395. DOI: http://dx.doi.org/10.5489/cuaj.4305
    86. Pabedinskas K, Kobrzynski M, Filler G. Successful Treatment of Multiple Angiomyolipomas with Sirolimus in a Child.  Indian J Nephrol 2017/05/01: 27 (3) p237-238.  doi: 10.4103/0971-4065.200520 / PMID 28553050.
    87. Pacheco I, Buzea C. (2017) Metal nanoparticles and their toxicity. In: Metal Nanoparticles. Synthesis and Applications in Pharmaceutical Sciences. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, ISBN: 978-3-527-33979-2. http://ca.wiley.com/WileyCDA/WileyTitle/productCd-3527339795.html.
    88. Pacheco I, Buzea C. (2017) Nanomaterials toxicity. In: Advanced Environmental Analysis: Applications of Nanomaterials. Vol. 2. The Royal Society of Chemistry, ISBN: 978-1-78262-907-8. http://pubs.rsc.org/en/content/ebook/978-1-78262-907-8#!divbookcontent .
    89. Papillon-Cavanagh S, Lu C, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu OM, Dhaliwal S, Stecho W, Howlett CJ, Mymryk JS, Barrett JW, Nichols AC, Allis CD, Majewski J, Jabado N. Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas. Nature Genetics 49, 180–185 (2017) DOI:10.1038/ng.3757. PMID: 28067913.
    90. Parfitt, J. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan 12;541(7636):169-175. doi: 10.1038/nature20805. Epub 2017 Jan 4. PMID:28052061.
    91. Parfitt, J. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 Mar 16;543(7645):378-384. doi: 10.1038/nature21386. Epub 2017 Jan 23. PMID: 28112728.
    92. Pena AM, Chen S, Li X, Liang G, Chakrabarti S . Prevention of Diabetic Nephropathy by modified acidic fibroblast growth factor.  Kidney International 2017/01/01.
    93. Pena AM, Chen S, Feng B, Cai L, Li X, Liang G, Chakrabarti S. Prevention of Diabetic Nephropathy by Modified Acidic Fibroblast Growth Factor. Nephron. 2017 Jul 29. doi: 10.1159/000478745. [Epub ahead of print]. PMID: 28768285.
    94. Prasad C, Napier MP, Rupar CA, Prasad C. Fumarase deficiency: A Rare Disorder on the Cross Roads of Clinical & Metabolic Genetics, Neurology and Cancer. Dysmorphology. Clin Dysmorphol. 2017 Apr;26(2):117-120. doi: 10.1097/MCD.0000000000000148. PMID: 27541980.
    95. Qadri SM, Bissinger R, Solh Z, Oldenborg PA. Eryptosis in health and disease: A paradigm shift towards understanding the (patho)physiological implications of programmed cell death of erythrocytes. Blood Rev. 2017 Nov;31(6):349-361. doi: 10.1016/j.blre.2017.06.001. Epub 2017 Jun 17. PMID: 28669393
    96. Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Baehner FL, Miller DP, Fong C, Gu S, Tuck A, Sengupta S, Elavathil L, Jani PA, Bonin M, Chang MC, Slodkowska E, Anderson JM, Cherbavaz DB, Shak S, Paszat L. Multigene Expression Assay and Benefit of Radiotherapy After Breast Conservation in Ductal Carcinoma in Situ. J Natl Cancer Inst. 2017 Jan 29;109(4). pii: djw256. DOI: 10.1093/jnci/djw256. Print 2017 Apr. PMID: 28132956.
    97. Ratmann O, Hodcroft EB, Pickles M, Cori A, Hall M, Lycett S, Colijn C, Dearlove B, Didelot X, Frost S, Hossain AS, Joy JB, Kendall M, Kühnert D, Leventhal GE, Liang R, Plazzotta G, Poon AF, Rasmussen DA, Stadler T, Volz E, Weis C, Leigh Brown AJ, Fraser C; PANGEA-HIV Consortium. Phylogenetic Tools for Generalized HIV-1 Epidemics: Findings from the PANGEA-HIV Methods Comparison.Mol Biol Evol. 2017 Jan;34(1):185-203. doi: 10.1093/molbev/msw217. Epub 2016 Oct 7. PMID:28053012.
    98. Richard C, Wadowski M, Goruk S, Cameron L, Sharma AM, Field CJ. Individuals with obesity and type 2 diabetes have additional immune dysfunction compared with obese individuals who are metabolically healthy. BMJ Open Diabetes Research and Care, Volume 5, Issue 1, 1 May 2017, Article number e000379.  DOI:10.1136/bmjdrc-2016-000379. PMID: 28761653.
    99. Sadler K, Johnson M, Brunette C, Gula L, Kennard M, Charland D, Tithecott G, Rieder M, Watling C, Herbert CP, Garcia B, Hammond RR. Indigenous Student Matriculation into Medical School: Policy and Progress. The International Indigenous Policy Journal 8(1).Retrieved from: http://ir.lib.uwo.ca/iipj/vol8/iss1/5. DOI 10.18584/iipj.2017.8.1.5.
    100. Santyr BG, Goubran M, Lau JC, Kwan BYM, Salehi F, Lee DH, Mirsattari SM, Burneo JG, Steven DA, Parrent AG, de Ribaupierre S, Hammond RR, Peters TM, Khan AR. Investigation of hippocampal substructures in focal temporal lobe epilepsy with and without hippocampal sclerosis at 7T. J Magn Reson Imaging, 2017 May 1; 45 (5): 1359-1370, Coauthor, DOI: 10.1002/jmri.25447.
    101. Schenkel LC, Rodenhiser D, Siu V, McCready E, Ainsworth P, Sadikovic B. Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors. J Pediatr Genet. 2017 Mar;6(1):30-41. [Epub 2016 Nov 8] DOI: 10.1055/s-0036-1593849 PMID: 28180025.
    102. Schenkel LC, Kernohan KD, McBride A, Reina D, Hodge A, Ainsworth PJ, Rodenhiser DI, Pare G, Bérubé NG, Skinner C, Boycott KM, Schwartz C, Sadikovic B. Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome. Epigenetics Chromatin. 2017 Mar 10;10:10. doi: 10.1186/s13072-017-0118-4. eCollection 2017 Mar 10. PMID: 28293299.
    103. Shi T, Wehrli BM. Monophasic Synovial Sarcoma of the Hypopharynx Excised by Transoral Laser Microsurgery.  Journal of Laryngology and Voice 2017/01/01. 
    104. Shirley B, Li Y, Knoll JHM, Rogan PK. Expedited radiation biodosimetry by automated dicentric chromosome identification and dose estimation, J Vis Exp. 2017 Sep 4;(127). doi: 10.3791/56245. PMID: 28892030.
    105. Srigley JA, Pelude L, Thampi N, Vayalumkal J, Amaratunga K, Bush K, Collet JC, Ellis C, Embree J, Forrester L, Frenette C, Henderson E, John MA, Johnston BL, Langley JM, Lee BE, Lefebvre M-A, Lemieux C, McGeer A, Noseworthy E, Quach C, Richardson S, Scien . Central Line-Associated Bloodstream Infections in Canadian Pediatric and Neonatal Intensive Care Units: 2009-2015.  Association of Medical Microbiology and Infectious Diseases Canada 2017/05/04.  
    106. Sullivan R, Mc Girr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L,  Dhanvantari S. Changes in the cardiac GHSR1a-Ghrelin system correlate with myocardial dysfunction in diabetic cardiomyopathy in mice.  Journal of the Endocrine Society, https://doi.org/10.1210/js.2017-00433.
    107. Tahmasebi H, Higgins V, Fung AWS, Truong D, White-Al Habeeb NMA, Adeli K. Pediatric Reference Intervals for Biochemical Markers: Gaps and Challenges, Recent National Initiatives and Future Perspectives.  EJIFCC 2017/03/01: 28 (1) p43-63.  / PMID 28439218.
    108. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan 12;541(7636):169-175. doi: 10.1038/nature20805. Epub 2017 Jan 4. PMID:28052061.
    109. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 Mar 16;543(7645):378-384. doi: 10.1038/nature21386. Epub 2017 Jan 23. PMID: 28112728.
    110. Thomas AA, Feng B, Chakrabarti S. ANRIL: A Regulator of VEGF in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):470-480. doi:10.1167/iovs.16-20569. PMID: 28122089.
    111. Thwaites M J, Cecchini MJ, Talluri S, Passos DT, Carnevale J, Dick FA. Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control. Cell Div. 2017; 12: 3. PMCID: PMC5348811 DOI: 10.1186/s13008-017-0029-6.
    112. Tijssen JA, Filler G. When CRRT on ECMO Is Not Enough for Potassium Clearance: A Case Report.  Can J Kidney Health Dis 2017/01/01: 4 p2054358117722559.  doi: 10.1177/2054358117722559 / PMID 28856008.
    113. Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ. Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders. Brain. 2017 Sep 1;140(9):2460-2474. doi: 10.1093/brain/awx172. PMID: 29050386
    114. Tota JE, Bentley J, Blake J, Coutlée F, Duggan MA, Ferenczy A, Franco EL, Fung-Kee-Fung M, Gotlieb W, Mayrand MH, McLachlin M, Murphy J, Ogilvie G, Ratnam S. Introduction of molecular HPV testing as the primary technology in cervical cancer screening: Acting on evidence to change the current paradigm. Prev Med. 2017 May;98:5-14. doi: 10.1016/j.ypmed.2016.11.029. Epub 2017 Feb 6. PMID: 28279264.
    115. Tota JE, Bentley J, Blake J, Coutlée F, Duggan MA, Ferenczy A, Franco EL, Fung-Kee-Fung M, Gotlieb W, Mayrand MH, McLachlin M, Murphy J, Ogilvie G, Ratnam S. Approaches for triaging women who test positive for human papillomavirus in cervical cancer screening. Prev Med. 2017 May;98:15-20. doi: 10.1016/j.ypmed.2016.11.030. Epub 2017 Feb 6. PMID: 28279257.
    116. Wang L, Huang Z, Huang W, Chen X, Shan P, Zhong P, Khan Z, Wang J, Fang Q, Liang G, Wang Y. Inhibition of epidermal growth factor receptor attenuates atherosclerosis via decreasing inflammation and oxidative stress. Sci Rep. 2017 Apr 4;8:45917. doi: 10.1038/srep45917. PMID: 28374780.
    117. White-Al Habeeb NM. Downregulation of PDZ Domain Containing 1 (PDZK1) is a Poor Prognostic Marker for Clear Cell Renal Cell Carcinoma.  EBioMedicine 2017/02/01: 16 p20-21.  doi: 10.1016/j.ebiom.2017.01.012 / PMID 28109828.
    118. White-Al Habeeb NMA, Earle T, Spencer M, Blasutig IM. Evaluation of the N-latex serum free light chain assay on the Siemens BNII analyzer and agreement with The Binding Site FreeLite assay on the SPAPlus.  Clin Biochem 2017/05/13:  doi: 10.1016/j.clinbiochem.2017.05.009 / PMID 28512013.
    119. Yan B, Feagan B, Teriaky A, Mosli M, Mohamed R, Williams G, Yeung E, Yong E, Haig A, Sey M, Stitt L, Zou GY, Jairath V. Reliability of EUS indices to detect inflammation in ulcerative colitis.Gastrointest Endosc. 2017 Jul 29. pii: S0016-5107(17)32158-2. doi: 10.1016/j.gie.2017.07.035. [Epub ahead of print]. PMID 28760533
    120. Yildirim ZK, Nexo E, Rupar T, Büyükavci M. Seven Patients With Transcobalamin Deficiency Diagnosed Between 2010 and 2014: A Single-Center Experience. J Pediatr Hematol Oncol. 2017 Jan;39(1):38-41. PMID: 27824740.
    121. Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. an aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation.Neuropathol Appl Neurobiol. 2017 Apr 12. doi: 10.1111/nan.12404. [Epub ahead of print]. PMID: 28403515.
    122. Zou C, Li W, Li J, Khan ZA, Pan Y, Wu X, Yin H, Wang J, Zheng C, Liang G. 11β-HSD1 inhibition ameliorates diabetes-induced cardiomyocyte hypertrophy and cardiac fibrosis through modulation of EGFR activity. Oncotarget. 2017 Oct 24;8(56):96263-96275. doi: 10.18632/oncotarget.22015. eCollection 2017 Nov 10. PMID: 29221204.

2016 Publications

    1. Schenkel LC, Schwartz C, Skinner C, Rodenhiser DI, Ainsworth PJ, Pare G, Sadikovic B.  Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.  J Mol Diagn. 2016 Nov;18(6):834-841.  doi: 10.1016/j.jmoldx.2016.06.005.  PMID: 27585064
    2. Schenkel LC, Rodenhiser DI, Ainsworth PJ, Paré G, Sadikovic B.  DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.  Crit Rev Clin Lab Sci. 2016;53(3):147-65.  DOIi: 10.3109/10408363.2015.1113496. Review.  PMID: 26758403
    3. Kernohan KD, Cigana Schenkel L, Huang L, Smith A, Pare G, Ainsworth P; Care4Rare Canada Consortium., Boycott KM, Warman-Chardon J, Sadikovic B.  Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy.  Clin Epigenetics. 2016 Sep 5;8:91. doi: 10.1186/s13148-016-0254-x.  PMID: 27602171 Free PMC Article
    4. Hood RL, Schenkel LC, Nikkel SM, Ainsworth PJ, Pare G, Boycott KM, Bulman DE, Sadikovic B. The defining DNA methylation signature of Floating-Harbor Syndrome. Sci Rep, 2016 Dec 9; 6: 38803.  DOI: 10.1038/srep38803. PMID 27934915.
    5. Iqbal J, Nussenzweig A, Lubinski J, Byrski T, Eisen A, Bordeleau L, Tung NM, Manoukian S, Phelan CM, Sun P, Narod SA, Hereditary Breast Cancer Research Group (incl. Ainsworth P). The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study. Br J Cancer, 2016 May 10; 114 (10): 1160-4.  DOI: 10.1038/bjc.2016.58. PMID 26986251.
    6. Gronwald J, Glass K, Rosen B, Karlan B, Tung N, Neuhausen SL, Moller P, Ainsworth P, Sun P, Narod SA, Lubinski J, Kotsopoulos J, Hereditary Breast Cancer Clinical Study Group. Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. Fertil Steril. 2016 Mar 1, 105. (3): p.781-5.  DOI: 10.1016/j.fertnstert.2015.11.034. PMID 26698676
    7. Florendo-Cumbermack A, Selchen D, Morrow SA, Sharma M, Steven D, Ang LC, Casserly C, Burneo J, Kremenchutzky M, Hammond R.   Everything Old is New Again.  Can J Neuro Sci.  Volume 43, Issue 1, 5 Jan 2016, Pages 213-218  DOI:  10.1017/cjn.2015.309
    8. Mattingly TK, Denning LM, Siroen KL, Lehrbass B, Lopez-Ojeda P, Stitt L, Pelz DM, Das S, Ang LC, Lee DH, Lownie SP. Catheter based selective hypothermia reduces stroke volume during focal cerebral ischemia in swine. J Neurointerv Surg. 2016 Apr;8(4):418-22. doi: 10.1136/neurintsurg-2014-011562. Epub 2015 Feb 12. PMID: 25676148
    9. Tong J, Fitzmaurice PS, Moszczynska A, Mattina K, Ang LC, Boileau I, Furukawa Y, Sailasuta N, Kish SJ. Do glutathione levels decline in aging human brain? Free Radic Biol Med, 2016 Apr; 93: 110-7. Doi: 10.1016/j.freeradbiomed.2016.01.029.
    10. Alturkustani M, Ang LC. Acute hypoxic-ischemia in cardiac arrest encephalopathy causes only minimal demyelination. Neuropathology 2016 Mar; doi:10.1111/neup.12287.
    11. Beamish CA, Strutt BJ, Arany EJ, Hill DJ. Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters. Islets. 2016 Mar 24:e1162367. [Epub ahead of print] PMID: 27010375
    12. Whitehead R, Guan H, Arany E, Cernea M, Yang K.  Prenatal exposure to bisphenol A alters mouse fetal pancreatic morphology and islet composition.  Horm Mol Biol Clin Investig.  2016 Mar;25(3):171-9. DOI: 10.1515/hmbci-2015-0052  PMID: 26812801.

    13. Quansah R, Bend JR, Abdul-Rahaman A, Armah FA, Luginaah I, Essumang DK, Iddi S, Chevrier J, Cobbina SJ, Nketiah-Amponsah E, Adu-Kumi S, Darko G, Afful S. Associations between pesticide use and respiratory symptoms: A cross-sectional study in Southern Ghana. Environ Res. 2016 Jun 16;150:245-254. doi: 10.1016/j.envres.2016.06.013. PMID: 27318967
    14. Palikhe NS, Laratta C, Nahirney D, Vethanayagam D, Bhutani M, Vliagoftis H, Cameron L. Elevated levels of circulating CD4(+) CRTh2(+) T cells characterize severe asthma. Clin Exp Allergy, 2016 Jun;46(6):825-36. DOI: 10.1111/cea.12741  PMID:  27079298.
    15. Ethier C, Yu Y, Cameron L, Lacy P, Davoine F.  Calcitriol Reduces Eosinophil Necrosis Which Leads to the Diminished Release of Cytotoxic Granules.  Int Arch Allergy Immunol. 2016;171(2):119-129. DOI: 10.1159/000450951. Epub 2016 Dec 1.  PMID:  27902981

    16. Campigotto A, Muller MP, Taggart LR, Haj R, Leung E, Nadarajah J, Matukas LM. Cumulative Antimicrobial Susceptibility Data from Intensive Care Units at One Institution: Should Data Be Combined? J Clin Microbiol, 2016 Apr 1; 54 (4): 956-9.  DOI: 10.1128/JCM.02992-15.

    17. Campigotto A, Richardson SE, Sebert M, McElvania TeKippe E, Chakravarty A, Doern CD. 2016. Low utility of pediatric isolator blood culture system for detection of fungemia in children: a 10-year review. J Clin Microbiol 54:2284–2287. DOI: 10.1128/JCM.00578-16.
    18. Thwaites MJ, Cecchini MJ, Passos DT, Welch I, Dick FA.  Interchangeable roles for E2F transcriptional repression by the retinoblastoma protein and p27KIP1-CDK regulation in cell cycle control and tumor suppression.  Mol Cell Biol. 2016 Nov 7. pii: MCB.00561-16. [Epub ahead of print]  DOI: 

      10.1128/MCB.00561-16  PMID:.27821477
    19. Ishak CA, Marshall AE, Passos DT, White CR, Seung KJ , Cecchini MJ, Ferwati S, MacDonald WA, Howlett CJ, Welch ID, Rubin SM, Mann MRW, Dick FA.  An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences.  Mol Cell Biol. 2016 Nov 23. [Epub ahead of print]  DOI:  10.1016/j.molcel.2016.10.021

    20. Gordon A, Feng B, Chakrabarti S Long Non-coding RNA malat-1 regulates inflammatory cytokines in chronic diabetic complications. Diabetes 2016 Jun; 65 (Supplement 1), A137/525-P
    21. Feng B, Chen S, Gordon A, Chakrabarti S. Antiinflammatory and antifibrotic effects of endothelial miRNA146 in the heart in diabetes. Diabetes 2016 Jun; 65 (Supplement 1); A125/474-P.
    22. Li B, Iordanous Y, Chakrabarti S, Alan LH, Adenoid Cystic Carcinoma Presenting as a Retro-orbital mass, Can J Ophthalmol. 2016 Apr;51(2):e65-7. doi: 10.1016/j.jcjo.2015.12.012.
    23. Feng B, Cao Y, Chen S, Chu X, Chu Y, Chakrabarti S. miR-200b mediates endothelial to mesenchymal transition in diabetic cardiomyopathy. Diabetes. 2016 Mar;65(3):768-79. doi: 10.2337/db15-1033. Epub 2015 Dec 30.
    24. Zhang Q, Hussey A, Ubaidat M, Chan N, Gomez JA. Malignant Mesothelioma of the Tunica Vaginalis Testis: A Case Report and Review of Literature. Canadian Journal of Pathology 2016/03/01 19-23 .
    25. Ostrakhovitch EA, Song YP,  Cherian MG. Basal and copper-induced expression of metallothionein isoform 1,2 and 3 genes in epithelial cancer cells: The role of tumor suppressor P53. Journal of Trace Elements in Medicine and Biology Volume 35, May 2016, Pages 18–29 DOI: 10.1016/j.jtemb.2016.01.008.
    26. Chin-Yee B, Lazo-Langner A, Butler-Foster T, Hsia C, Chin-Yee I. Blood donation and testosterone replacement therapy. Transfusion. 2017 Mar;57(3):578-581. doi: 10.1111/trf.13970. Epub 2017 Feb 1. PMID: 28150363.
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    27. Hsia CC, Mahon JL, Seitelbach M, Chia J, Zou G, Chin-Yee IH. Use of n-of-1 (single patient) trials to assess the effect of age of transfused blood on health-related quality of life in transfusion-dependent patients. Transfusion, 2016 May 1; 56 (5): 1192-200.  DOI: 10.1111/trf.13484. PMID 26840915

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    105. Schaeffer DF, Walsh JC, Tyler AD, Ben-Bassat O, Silverberg MS, Riddell RH, Kirsch R. Intra-epithelial lymphocytosis is a frequent finding in biopsies from ileal pouch-anal anastomoses (IPAA). Hum Pathol  2016 Apr 7. 1753-1772 [epub ahead of print] DOI:  10.1016/j.humpath.2016.03.007 PMID:  27063473
    106. Shoker A, Xu Q, Lim HJ.   Differential Association Between Responder’s HLA-DR Phenotypes and HLD-DR Antibody Production in Patients Awaiting for Renal Transplantation; Analysis of UNOS Database. J Clin Exp Transplant 1:103. DOI: 10.4172/jcet.1000103

    107. Wang H, Zhang X, Zheng X, Lan Z, Sh, J, Jiang J, Zwiep T, Li Q, Quan D, Zhang Z-X, Min W. Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways. Sci Rep. 2016 Sep 23;6:33869. doi: 10.1038/srep33869. PMID 27659428

    108. Liu Y, Zhang Y, Zheng X, Zhang X, Wang H, Li Q, Yuan K, Zhou N, Yu Y, Song N, Fu J, Min W. Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth. Oncotarget 2016 Apr 6. DOI: 10.18632/oncotarget.8617. [Epub ahead of print] PMID: 27058624
    109. Zheng X, Zang G, Jiang J, He W, Johnston NJ, Ling H, Chen R, Zhang X, Liu Y, Haig A, Luke P, Jevnikar AM, Min WP. Attenuating Ischemia-Reperfusion Injury in Kidney Transplantation by Perfusing Donor Organs With siRNA Cocktail Solution. Transplantation. 2016 Apr;100(4):743-52. doi: 10.1097/TP.0000000000000960.

2015 Publications

    1. Cybulski C, Lubinski J, Huzarski T, Lynch HT, Randall SA, Neuhausen SL, Senter L, Friedman S,  Ainsworth P, Singer C, Foulkes WD, Narod SA, Sun P, Kotsopoulos J.  Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.  Breast Cancer Res Treat. 2015 Jun;151(2):435-41. doi: 10.1007/s10549-015-3393-4. PMID:  25935583. Epub 2015 May 3.
    2. Kotsopoulos J, Lubinski J, Neuhausen SL, Gronwald J, Lynch HT, Huzarski T, Demsky R, Foulkes WD, Senter L, Friedman S,  Ainsworth P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Weight gain after oophorectomy among women with a BRCA1 or BRCA2 mutation.  Womens Health (Lond Engl). 2015 Jul;11(4):453-9  DOI:  10.2217/WHE.15.4  PMID:  26258912
    3. Semple J, Metcalfe KA, Lubinski J, Huzarski T, Gronwald J, Armel S, Lynch HT, Karlan B, Foulkes W, Singer CF, Neuhausen SL, Eng C, Iqbal J, Narod SA, Hereditary Breast Cancer Clinical Study Group (incl. Ainsworth, P). Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers? Breast Cancer Res Treat, 2015 Nov 1; 154 (1): 163-9.   DOI: 10.1007/s10549-015-3596-8. PMID 26467043.
    4. Nikitina D, Chen Z, Vallis K, Poll A, Ainsworth P, Narod SA, Kotsopoulos J. Relationship between Caffeine and Levels of DNA Repair and Oxidative Stress in Women with and without a BRCA1 Mutation. J Nutrigenet Nutrigenomics, 2015 Jan 1; 8 (4-6): 174-84.  DOI: 10.1159/000439110. PMID 26670362.
    5. Alturkustani M, Mandzia J, Watling C, Cooper P, Bahakeen B, Leung A, Gulka I,  Howlett CHammond R.  CNPC: Acute myelopathy in a 68 year old male.  Can J Neurol Sci.  2015; 42: 466-471 DOI: 10.1017/cjn.2015.305
    6. Alturkustani M, Keith J, Hazrati LN, Rademakers R,  Ang LC.  Pathologic staging of white matter lesions in adult-onset leukoencephalopathy/leukodystrophy with axonal spheroids  J Neuropathol Exp Neurol. Top of Form2015 Mar;74(3):233-40  DOI:  10.1097/NEN.0000000000000168  PMID:  25668567
    7. Kertesz A, Finger E, Murrell J, Chertkow H,  Ang LC, Baker M, Ravenscroft T, Rademakers R, Muno, DG.  Progressive Supranuclear Palsy in a family with TDP-43 pathology.  Neurocase, Volume 21, Issue 2, 4 March 2015, Pages 178-184.  doi: 10.1080/13554794.2013.878729.
    8. Tong J,  Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ.  Low levels of astroglial markers in Parkinson's disease: relationship to α-synuclein accumulation.  Neurobiol Dis 2015 Jun 21;82:243-253  DOI:  10.1016/j.nbd.2015.06.010  PMID:  26102022
    9. Abuzgaia AM, Hardy DB,  Arany E. Regulation of postnatal pancreatic Pdx1 and downstream target genes after gestational exposure to protein restriction in rats. Reproduction (2015) 149 293–303. DOI: 10.1530/REP-14-0245 ISSN 1470–1626 (paper) 1741–7899 (online).
    10. Asfaha S, Hayakawa Y, Muley A, Stokes S, Graham, TA, Ericksen RE, Westphalen CB, vonBurstin J, Mastracci TL, Worthley DL, Guha C, Quante M, Rustgi AK, Wang TC.  Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine.  J.Stem Volume 16, Issue 6, 4 June 2015, Pages 627-638  DOI:  10.1016/j.stem.2015.04.013.
    11. Tsimbiri, P.F., Moturi, W.N., Sawe, J., Henley, P. and  Bend, J.R. Health impact of pesticides on residents and horticultural workers in the Lake Naivasha Region, Kenya. Occupational Diseases and Environmental Medicine. 3: 24-34, 2015.  http://dx.doi.org/10.4236/odem.2015.32004
    12. Jeurissen S,  Bend JR. Aliphatic and Alicyclic Hydrocarbons (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 169-193.
    13. Williams GM,  Bend JR. Monocyclic and Bicyclic Secondary Alcohols, Ketones and Related Esters (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 263-276.
    14. Jeurissen S.  Bend JR. Phenyl-Substituted Aliphatic Alcohols and Related Aldehydes and Esters (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 297-315.
    15. Williams GM,  Bend JR. Miscellaneous Nitrogen-Containing Substances (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 241-261.
    16. Tsimbiri PF, Moturi WN, Sawe J, Henley P,  Bend JR. Health impact of pesticides on residents and horticultural workers in the Lake Naivasha Region, Kenya. ODEM. 3: 24-34, 2015. DOI:  10.4236/odem.2015.32004
    17. Bend JR, Xia XY, Chen DF, Awaysheh A, Lo A, Rieder MJ, Rylett  RJ. Attenuation of oxidative stress in HEK 293 cells by the TCM constituents schisanhenol, baicalein, resveratrol or crocetin and two defined mixtures. J Pharm Pharm Sci. 18: 661-682, 2015
    18. Zhang L, Chen DF, Xia XY, Yip C, Rieder MJ,  Bend JR. Potential complementary therapy for adverse drug reactions to sulfonamides: Chemoprotection against oxidative and nitrosative stress by TCM constituents and defined mixtures J Pharm Pharm Sci. 18: 528-546, 2015
    19. Cecchini MJ, Ishak CA, Passos DT, Warner A, Palma DA,  Howlett CJDriman DK, Dick FA.  Loss of the retinoblastoma tumor suppressor correlates with improved outcome in patients with lung adenocarcinoma treated with surgery and chemotherapy.  Hum Pathol. 2015 Dec;46(12):1922-34. DOI: 10.1016/j.humpath.2015.08.010. PMID:  26475095
    20. Cecchini MJ, Yu E, Potvin K, D'Souza, D, Lock MM.  Concurrent or Sequential Hormonal and Radiation Therapy in Breast Cancer: A LiteratureReview.  Cureus 7(10): e364. 2015 10 DOI:10.7759/cureus.364 
    21. Daley T, Dunn G,  Darling MR. Central xanthoma of the jaws: A clinicopathologic entity?  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Volume 119, Issue 1, 1 January 2015, Pages 92-100 DOI: 10.1016/j.oooo.2014.09.018.
    22. Delport JA, Peters G, Diagre D,  Lannigan RJohn MA. Identification of Coagulase-Negative Staphylococci by the Bruker MALDI-TOF BioTyper Campared to the VITEK 2 and MIS Gas Liquid Chromatography. J Bacteriol Mycol Open Access, 2015 Jun: 1(1): 00003.  DOI: 10.15406/jbmoa.2015.01.00003
    23. Al-Judaibi B,  Driman DK, Chandok N.  An elderly lady with significant weight loss.  Arab J Gastroenterol. 2015 Mar 14. pii: S1687-1979(14)00075-6. [Epub ahead of print]   DOI:  10.1016/j.ajg.2014.10.003  PMID:  25784461.
    24. O'Connor K, Li-Chang HH, Kalloger SE, Peixoto RD, Webber DL, Owen DA,  Driman DK, Kirsch R, Serra S, Scudamore CH, Renouf DJ, Schaeffer DF.  Tumor budding is an independent adverse prognostic factor in pancreatic ductal adenocarcinoma  Am J Surg Pathol. 2015 Apr;39(4):472-8  DOI:  10.1097/PAS.0000000000000333  PMID:  25634751.
    25. Wells M,  Driman DK, Al-Judaibi B.  A treatable mimicker of cholangiocarcinoma.  Can J Gastroenterol Hepatol. 2015 Aug-Sep;29(6):291-2.  PMID:  26361640
    26. Vilos, GA, Oraif, A, Vilos, AG,  Ettler, H, Edris, F, Abu-Rafea, B.  Long-term clinical outcomes following resectoscopic endometrial ablation of non-atypical endometrial hyperplasia in women with abnormal uterine bleeding.  Journal of Minimally Invasive Gynecology, Volume 22, Issue 1, 1 January 2015, Pages 66-77.  DOI: 10.1016/j.jmig.2014.07.009  PMID: 25749467.
    27. Samaan S, Khella HWZ, Girgis A, Scorilas A, Lianidou E,  Gabril M, Krylov SN, Jewett M, Bjarnason GA, El-Said H, Yousef GM.  MiR-210 is a prognostic marker in clear cell renal cell carcinoma   Journal of Molecular Diagnostics , 17 ( 2 ) pp. 136 - 144 DOI:  10.1016/j.jmoldx.2014.10.005  PMID:  25555365.
    28. Karamchandani JR,  Gabril MY, Ibrahim R, Scorilas A, Filter E, Finelli A, Lee JY, Ordon M, Pasic M, Romaschin AD, Yousef GM.  Profilin-1 expression is associated with high grade and stage and decreased disease-free survival in renal cell carcinoma  Hum Pathol 2015 May;46(5):673-80 DOI:  10.1016/j.humpath.2014.11.007  PMID:  25704627
    29. Gabril M, Girgis H, Scorilas A, Rotondo F, Wala S, Bjarnason GA, Ding Q, Evans A, Tawedrous E, Pasic M, Finelli A, Al-Haddad S, Yousef GM.  S100A11 is a potential prognostic marker for clear cell renal cell carcinoma.  Clin Exp Metastasis. 2015 Oct 15. [Epub ahead of print]  PMID:  26472670
    30. White-Al Habeeb NM, Di Meo A, Scorilas A, Rotondo F, Masui O, Seivwright A,  Gabril M, Girgis AHA, Jewett MA, Yousef GM.  Alpha-enolase is a potential prognostic marker in clear cell renal cell carcinoma.  Clin Exp Metastasis. 2015 Aug;32(6):531-41  DOI:  10.1007/s10585-015-9725-2  PMID:  26037892
    31. Rizek P, Ikeda KM, Mele T,  Garcia B, Gofton TE.  Bowel Ischemia in Refractory Status Epilepticus: Report of Two Cases and Review of the Literature  Neurocrit Care. 21 July 2015, 4p  DOI:  10.1007/s12028-015-0181-2  PMID:  26195088  [Epub ahead of print]
    32. Zhang ZX, Huang X, Jiang J, Lau A, Yin Z, Liu W,  Haig A, Jevnikar AM.Top of Form Natural Killer Cells Mediate Long-term Kidney Allograft Injury  Transplantation 2015 May;99(5):916-24 DOI:  10.1097/TP.0000000000000665 PMID:  25719259
    33. Yan, Y, Zhang ZX, Lian D,  Haig A, Bhattacharjee RN, Jevnikar AM.  IL-37 inhibits IL-18-induced tubular epithelial cell expression of pro-inflammatory cytokines and renal ischemia-reperfusion injury  Kidney International  87 ( 2 ) pp. 396 – 408  DOI: 10.1038/ki.2014.295 PMID:  25207880
    34. Ismail OZ, Zhang X, Wei J,  Haig A, Denker BM, Suri RS, Sener A, Gunaratnam L.  Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury  Am J Pathol.  2015 May;185(5):1207-15  DOI:  10.1016/j.ajpath.2015.02.003  PMID:  25759266
    35. Czikk MJ, Totten S,  Hammond RR, Richardson BS.  MAP-2 and Synaptophysin in the Preterm and Near-term Ovine Fetal Brain and the effect of Intermittent Umbilical Cord Occlusion.  Reprod Sci. 2015, Vol. 22(3) 367-37, epub 2014 Apr 3. DOI: 10.1177/1933719114529371. PMID: 24700051
    36. Goubran M, DeRibaupierre S,  Hammond RR, Currie C, Burneo JG, Parrent AG, Peters TM, Khan AR.Registration of in-vivo to ex-vivo MRI of surgically resected specimens: A pipeline for histology to in-vivo registration.  J Neurosci Methods. 2015 Feb 15;241:53-65 DOI: 10.1016/j.jneumeth.2014.12.005. Epub 2014 Dec 13.  PMID: 25514760
    37. Goubran M,  Hammond RR, de Ribaupierre S, Burneo JG, Mirsattari S, Steven DA,  Parrent AG,  Peters TM,.Khan AR.  Magnetic resonance imaging and histology correlation in the neocortex in temporal lobe epilepsy.  Ann Neurol. 2015 Feb;77(2):237-50. DOI: 10.1002/ana.24318. Epub 2014 Dec 17  PMID: 25514760  (Cover Article)
    38. Pasarikovski C,  Allevato P,  Hammond RR, Elashaal A.  Pilocytic astrocytoma of the lower thoracic spine in an adult patient.  Acta Neurochir (Wien). 2015 Jul;157(7):1179-81  DOI: 10.1007/s00701-015-2458-9. Epub 2015 May 31.  PMID: 26024949
    39. Torchia J, Picard D, Lafay-Cousin L, Hawkins CE, Kim SK, Letourneau L, Ra YS, Ho KC, Chan TS, Sin-Chan P, Dunham CP, Yip S, Ng HK, Lu JQ, Albrecht S, Pimentel J, Chan JA, Somers GR, Zielenska M, Faria CC, Roque L, Baskin B, Birks D, Foreman N, Strother D, Klekner A, Garami M, Hauser P, Hortobágyi T, Bognár L, Wilson B, Hukin J, Carret AS, Van Meter TE, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheineman K, Johnston D, Michaud J, Zelcer S,  Hammond RRamsay DA, Fleming AJ, Lulla RR, Fangusaro JR, Sirachainan N, Larbcharoensub N, Hongeng S, Barakzai MA, Montpetit A, Stephens D, Grundy RG, Schüller U, Nicolaides T, Tihan T, Phillips J, Taylor MD, Rutka JT, Dirks P, Bader GD, Warmuth-Metz M, Rutkowski S, Pietsch T, Judkins AR, Jabado N, Bouffet E, Huang A.  Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.  Lancet Oncol. 2015 May;16(5):569-82.  DOI: 10.1016/S1470-2045(15)70114-2. Epub 2015 Apr 14. PMID:  25882982
    40. Xu A, Matushewski B, Cao M,  Hammond R, Frasch MG, Richardson BS.  The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.  Reprod Sci. 2015 Apr 15. pii: 1933719115580994. [Epub ahead of print]  PMID:  25878209
    41. Zeineh MM, Chen Y, Kitzler HH,  Hammond R, Vogel H, Rutt BK.  Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease.   Neurobiol Aging. 2015 Sep;36(9):2483-500. DOI:10.1016/j.neurobiolaging.2015.05.022. Epub 2015 Jun 6.  PMID:  26190634
    42. Magaki S, Chang E,  Hammond RR, Yang I, Mackenzie IR, Chou BT, Choi SI, Jen JC, Pope WB, Bell DA, Vinters HV. Two cases of rheumatoid meningitis. Neuropathology. 2015 Sep 8. DOI: 10.1111/neup.12238. [Epub ahead of print]  PMID: 26350538.
    43. Ikeda KM, Das S, Strong M, Mirsattari SM, Leung A, Steven D,  Hammond R.  Diagnosis of Inclusion Can J Neurol Sci. 2015; 24: 138-143
    44. Taylor G, Gravel D, Saxinger L, Bush K, Simmonds K, Matlow A, Embree J, Le Saux NL, Johnston L, Suh KN, Embil J, Henderson E,  John M, Roth V, Wong A, Bryce E, Dow G, Gardam M, Hutchinson J, Kibsey P, Langley J, Loeb M, McGeer A, Michaud S, Miller M, Moore D, Mulvey M, Ofner M, Paton S, Stegenga J, Weiss K, Zoutman D.  Prevalence of antimicrobial use in a network of Canadian hospitals in 2002 and 2009.  Can J Infect Dis Med Microbiol March/April 2015, Volume 26 Issue 2: 85- 89
    45. Schick BA, Tobe JS,  Joseph MG, Rouse TB,  Gabril MY.   Incidental Merkel Cell Carcinoma in a Cutaneous Horn: A Case Report. Dermatol Pract Concept. 2015 Jan; 5(1): 47–50. Published online 2015 Jan 30. DOI:  10.5826/dpc.0501a08  PMCID: PMC4325691
    46. Joseph MG, Shibani A, Panjwani N, Arab A,  Shepherd J, Stitt W,  Inculet R.  Usefulness of Ki-67, Mitoses, and Tumor Size for Predicting Metastasis in Carcinoid Tumors of the Lung: A Study of 48 Cases at a Tertiary Care Centre in Canada. Lung cancer international Volume 2015, Article ID 545601, 7 pages DOI:  10.1155/2015/545601
    47. Kum JY,  Khan  ZA   Mechanisms of propranolol action in infantile hemangioma.  Dermato-Endocrinology, 6:1, e979699  DOI:  10.4161/19381980.2014.979699
    48. Dorman SN, Baranova K,  Knoll JH, Urquhart BL, Mariani G, Carcangiu ML, Rogan PK.  Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning.  Mol Oncol. 2015 Aug 22. pii: S1574-7891(15)00146-5   [Epub ahead of print]  DOI:  10.1016/j.molonc.2015.07.006  PMID:  26372358
    49. Khan WA, Rogan PK,  Knoll JH.  Reversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes.  Mol Cytogenet. 2015 Aug 13;8:65  DOI:  10.1186/s13039-015-0159-y  PMID:  26273322
    50. Lerner-Ellis J, Wang M, White S, Lebo MS; Knoll J and Canadian Open Genetics Repository Group. 

      Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardizing and sharing genetic interpretations. 

      J Med Genet. 2015 Jul;52(7):438-45. doi: 10.1136/jmedgenet-2014-102933. Epub 2015 Apr 22. PMID: 25904639

    51. Parsons P, Sedig K, Mercer RE, Khordad M, Knoll J, Rogan P. Visual Analytics for supporting evidence-based interpretation of molecular cytogenomic findings (conference paper). ACM International Conference Proceeding Series Volume 25-October-2015, 25 October 2015, Article number 2. 2015 Workshop on Visual Analytics in Healthcare, VAHC 2015; Chicago; United States; 25 October 2015; Code 119172
    52. Theurer JA, Stecho W, Yoo J,  Kwan KWehrli B, Harry V, Black M, Pinto N, Winquist E, Palma D, Richter S, Barrett JW, Danielle MacNeil S, Fung K,  Howlett CJ, Nichols AC.  Feasibility of Targeting PIK3CA Mutations in Head and Neck Squamous Cell Carcinoma.  Pathol Oncol Res. 2015 Aug 14. [Epub ahead of print]  PMID:  26271341
    53. Owrangi AM,  Lannigan R, Simonovic SP.  Mapping climate change-caused health risk for integrated city resilience modeling.  Nat Hazards  6 January 2015, 22p  doi: 10.1007/s11069-014-1582-9.
    54. Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G,  Sadikovic B. Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia. Eur J Haematol. 2015 Jun 8.  DOI: 10.1111/ejh.12597. [Epub ahead of print]  PMID:26059983 
    55. Decker KM,  McLachlin CM, Lotocki R; Pan-Canadian Cervical Cancer Screening Network Monitoring Program Performance Working Group.  Performance measures related to colposcopy for canadian cervical cancer screening programs: identifying areas for improvement. J Obstet Gynaecol Can. 2015 Mar;37(3):245-51.  PMID:  26001871
    56. Hemmett J, Qirjazi E, Weir MA,  Moussa M, Landry YD, Gunaratnam L.  Cardiac, renal, and central nervous system dysfunction with eosinophilia: Eosinophilic granulomatosis with polyangiitis.  Lancet 2015 Jan 31;385(9966):480  DOI:  10.1016/S0140-6736(14)62352-7  PMID:  25706976.
    57. Imani F, Ramezani M, Nouranian S, Gibson E, Khojaste A, Gaed M,  Moussa M, Gomez JA, Romagnoli C, Leveridge M, Chang S, Fenster A, Siemens DR, Ward AD, Mousavi P, Abolmaesumi P  Ultrasound-Based Characterization of Prostate Cancer Using Joint Independent Component Analysis.  IEEE Trans Biomed Eng. 2015 Jul;62(7):1796-804 DOI:  10.1109/TBME.2015.2404300  PMID:  25720016
    58. Sy K,  Parfitt J, Marginean C, Riddell RH, Streutker CJ.  Inflammatory pseudotumours of the oesophagus - histological and immunohistochemical findings. Histopathology 2015 Jun;66(7):1003-9  doi:  10.1111/his.12615  PMID:  25393329
    59. Torchia J, Picard D, Lafay-Cousin L, Hawkins CE, Kim S-K, Letourneau L, Ra Y-S, Ho KC, Chan TSY, Sin-Chan P, Dunham CP, Yip S, Ng H-K, Lu J-Q, Albrecht S, Pimentel J, Chan JA, Somers GR, Zielenska M, Faria CC, Roque L, Baskin B, Birks D, Foreman N, Strother D, Klekner A, Garami M, Hauser P, Hortobágyi T, Bognár L, Wilson B, Hukin J, Carret A-S, Van Meter TE, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheineman K, Johnston D, Michaud J, Zelcer S, Hammond R,  Ramsay DA, Fleming AJ, Lulla RR, Fangusaro JR, Sirachainan N, Larbcharoensub N, Hongeng S, Barakzai MA, Montpetit A, Stephens D, Grundy RG, Schüller U, Nicolaides T, Tihan T, Phillips J, Taylor MD, Rutka JT, Dirks P, Bader GD, Warmuth-Metz M, Rutkowski S, Pietsch T, Judkins AR, Jabado N, Bouffet E, Huang A.  Molecular subgroups of atypical teratoid rhabdoid tumours in children: An integrated genomic and clinicopathological analysis.  The Lancet Oncology  Volume 16, No. 5, p569–582, May 2015  DOI:  10.1016/S1470-2045(15)70114-2 
    60. Alahmadi M, Chin-Yee IH, Gupta K,  Rizkalla K, Hsia CC.  Leishmaniasis involving the bone marrow of a patient with multiple myeloma  Ann Hematol. 2015 Aug;94(8):1417-8  DOI:  10.1007/s00277-015-2376-1  PMID: Top of Form25876738
    61. Shapiro R,  Rizkalla K, Lam S.  Extensive Bone Marrow Necrosis in a Case of Acute Myeloid Leukemia Transformed from a Myeloproliferative Neoplasm  Case Rep Oncol Vol. 8, No. 2, 2015  DOI:  10.1159/000438822
    62. Tao A, Song J, Lan T, Xu X, Kvietys P, Kao R, Martin C,  Rui T.  Cardiomyocyte-fibroblast interaction contributes to diabetic cardiomyopathy in mice: Role of HMGB1/TLR4/IL-33 axis.  Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2075-85.  DOI:  10.1016/j.bbadis.2015.07.015  PMID:  26209013
    63. Farhan SMK, Wang J, Robinson JF, Prasad AN,  Rupar CA, Siu VM, Hegele RA.  Old gene, new phenotype: Mutations in heparan sulfate synthesis enzyme, EXT2 leads to seizure and developmental disorder, no exostoses  J Med Genet [Article in press]  DOI: 10.1136/jmedgenet-2015-103279
    64. Gannavarapu S, Prasad C, DiRaimo J, Napier M, Goobie S, Potter M, Chakraborty P, Karaceper M, Munoz T, Schulze A, MacKenzie J, Li L, Geraghty MT, Al-Dirbashi OY,  Rupar  CA.  Biotinidase deficiency: Spectrum of molecular, enzymatic and clinical information from newborn screening Ontario, Canada (2007-2014)  Mol Genet Metab. 2015 Aug 31. pii: S1096-7192(15)30044-5  DOI:  10.1016/j.ymgme.2015.08.010. [Epub ahead of print]  PMID:  26361991
    65. Lanktree MB, Lanktree BB, Paré G, Waye JS,  Sadikovic B, Crowther MA.  Examining the clinical use of hemochromatosis genetic testing. Canadian Journal of Gastroenterology and Hepatology.  Volume 29, Issue 1, 1 January 2015, Pages 41-45.  PMID25706573
    66. Zeesman S, Mccready E,  Sadikovic B, Nowaczyk MJ.  Prader-Willi syndrome and Tay-Sachs disease in association with mixed maternal uniparental isodisomy and heterodisomy 15 in a girl who also had isochromosome Xq.  American Journal of Medical Genetics, Part A.  Volume 167, Issue 1, 1 January 2015, Pages 180-184.  DOI: 10.1002/ajmg.a.36790.
    67. Boycott K, Hartley T, Adam S, Bernier F, Chong K, Fernandez BA, Friedman JM, Geraghty MT, Hume S, Knoppers BM, Laberge AM, Majewski J, Mendoza-Londono R, Meyn MS, Michaud JL, Nelson TN, Richer J,  Sadikovic B, Skidmore DL, Stockley T, Taylor S, van Karnebeek C, Zawati MH, Lauzon J, Armour CM; Canadian College of Medical Geneticists.  The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists. J Med GenetTop of Form 2015 Jul;52(7):431-7  DOI:  10.1136/jmedgenet-2015-103144  PMID:  25951830
    68. Lerner-Ellis J, Wang M, White S, Lebo MS; Canadian Open Genetics Repository Group (incl  Sadikovic, B). The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position statement of the Canadian College of medical geneticists.  J Med Genet. 52 ( 7 ) pp. 438 – 445  DOI:  10.1136/jmedgenet-2014-102933  PMID:  25904639
    69. Sangle NA, Taylor SL, Emond MJ, Depot M, Overholt BF, Bronner MP.  Overdiagnosis of high-grade dysplasia in Barrett’s esophagus: a multicenter, international study.  Modern Pathology (2015) 28, 758–765  DOI:  10.1038/modpathol.2015.2
    70. Agarwal AM, Liew Ma, Nussenzveig RH,  Sangle N, Heikal N, Yaish H, Christensen R.  Improved harmonization of eosin-5-maleimide binding test across different instruments and age groups.  Cytometry B Clin Cytom. 2015 Sep 18 [Epub ahead of print]  DOI:  10.1002/cyto.b.21326  PMID:  2638460
    71. Schick BA, McLean CA, Driman DK.  Negative colorectal polyp biopsies: the utility of cutting deeper levels.   Virchows Arch. 2015 Oct 16. [Epub ahead of print]  PMID:  26475150
    72. Rakovitch E, Nofech-Mozes S, Hanna W, Baehner FL, Saskin R, Butler SM,  Tuck A, Sengupta S, Elavathil S,  Jani PA, Bonin M, Chang MC, Robertson SJ, Slodkowska E, Fong C, Anderson JM, Jamshidian F,  Miller DP, Cherbavaz DB,  Shak S, Paszat L.  A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by beast-conserving surgery alone  Breast Cancer Res Treat. 2015; 152(2): 389–398.  DOI:  10.1007/s10549-015-3464-6  PMID:  4491104
    73. Anborgh P, Caria LBR, Chambers AF,  Tuck AB, Stitt LW,  Brackstone M  Role of plasma osteopontin as a biomarker in locally advanced breast cancer  Am J Transl Res  2015; 7(4): 723–732  PMID:  26064440
    74. Klein J, Kong I, Paszat L, Nofech-Mozes S, Hanna W, Thiruchelvam D, Narod SA, Saskin R, Done SJ, Miller N, Youngson B,  Tuck A, Sengupta S, Elavathil L, Jani PA, Slodkowska E, Bonin M, Rakovitch E.  Close or positive resection margins are not associated with an increased risk of chest wall recurrence in women with DCIS treated by mastectomy: a population-based analysis  Springerplus. 2015 Jul 10;4:335  DOI:  10.1186/s40064-015-1032-5  PMID:  26185737
    75. Sultan A, Goela A,  Tweedie E, Awan K, Lavi S.  Multimodality Imaging for Assessment of Coronary Embolus.  Can J Cardiol. Volume 31, Issue 3, 1 March 2015, Pages 364.e5-364.e7 DOI:  10.1016/j.cjca.2014.12.010  PMID:  25746026
    76. Sarr O, Blake A, Thompson J, Zhao L, Rabicki K, Walsh JC, Welch I, Regnault TR. The differential effects of low birth weight and western diet consumption upon early life hepatic fibrosis development in guinea pig. J Physiol 2015 Dec 10 DOI: 10.1113/JP271777. [Epub ahead of print] PMID: 26662996
    77. Zhang Q, Pocrnich C, Kurian A, Hahn AF, Howlett C, Shepherd J, Rizkalla K. Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: a clinicopathologic study of 5 cases. Pathol Res Pract 2015 Sep 5. [epub ahead of print] DOI: 10.1016/j.prp.2015.08.007 PMID: 26847730

2014 Publications

    1. Phelan CM, Iqbal J, Lynch HT, Lubinski J, Gronwald J, Moller P, Ghadirian P, Foulkes WD, Armel S, Eisen A, Neuhausen SL, Senter L, Singer CF, Ainsworth P, Kim-Sing C, Tung N, Llacuachaqui M, Chornokur G, Ping S, Narod SA, Hereditary Breast Cancer Study Group. Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study. Br J Cancer. 2014 Jan 21;110(2):530-4.530-4 doi:10.1038/bjc.2013.741. PMID24292448
    2. Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, Eisen A, Gilchrist D, Blum JL, Zakalik D, Pal T, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group ( Ainsworth P, et al). Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Res Treat579-86 doi:10.1007/s10549-013-2. PMID24458845
    3. Finch AP, Lubinski J, Møller P, Singer CF, Karlan B, Senter L, Rosen B, Maehle L, Ghadirian P, Cybulski C, Huzarski T, Eisen A, Foulkes WD, Kim-Sing C, Ainsworth P, Tung N, Lynch HT, Neuhausen S, Metcalfe KA, Thompson I, Murphy J, Sun P, Narod SA. Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation. J Clin Oncol1547-53 doi:10.1200/JCO.2013.53.  PMID24567435
    4. Kertesz A, Finger E, Murrell J, Chertkow H, Ang LC, Baker M, Ravenscroft T, Rademakers R, Munoz DG. Progressive Supranuclear Palsy in a family with TDP-43 pathology. Neurocase doi:10.1080/13554794.201. PMID24479957
    5. Tong J, Fitzmaurice P, Furukawa Y, Schmunk GA, Wickham DJ, Ang LC, Sherwin A, McCluskey T, Boileau I, Kish SJ. Is brain gliosis a characteristic of chronic methamphetamine use in the human? Neurobiol Dis 107-18 doi:10.1016/j.nbd.2014.0. PMID24704312
    6. Lin AW, Das S, Fraser JA, Ang LC, Florendo-Cumbermack A, Jenkins ME, Tay KY. Emergence of Primary CNS Lymphoma in a Patient with Findings of CLIPPERS. Can J Neurol Sci. 2014 Jul;41(4):528-9.528-9.  PMID24878484
    7. Henley P, Lowthers M, Koren G, Fedha PT, Russell E, VanUum S, Arya S, Darnell R, Creed IF, Trick CG, Bend JR. Cultural and socio-economic conditions as factors contributing to chronic stress in sub-Saharan African communities. Can J Physiol Pharmacol. 92:725-32, 2014.
    8. Xiao J, Li J, Cai L, Chakrabarti S, Li X. Cytokines and diabetes research. Journal of Diabetes Research, Volume 2014, 2014, Article number 920613 PMID24551859
    9. Mortuza R, Chakrabarti S. Glucose-induced cell signaling in the pathogenesis of diabetic cardiomyopathy. Heart Fail Rev, 75-86 doi:10.1007/s10741-013-9. PMID23430126
    10. Chen S, Puthanveetil P, Feng B, Matkovich SJ, Dorn GW, Chakrabarti S. Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes. Journal of Cellular and Molecular MedicineVolume 18, Issue 3, March 2014, Pages 415-421. PMID24428157
    11. Feng B, Cao Y, Chen S, Ruiz M, Chakrabarti S. miRNA-1 regulates endothelin-1 in diabetes. Life Sci2014 Mar 7;98(1):18-23, doi:10.1016/j.lfs.2013.12.199. Epub 2014 Jan 3.  PMID24394957
    12. Cong W, Zhao T, Zhu Z, Huang B, Ma W, Wang Y, Tan Y, Chakrabarti S, Li X, Jin L, Cai L. Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase. J Nutr Biochem 463-74, doi:10.1016/j.jnutbio.20. PMID24629910
    13. Beaton MD, Chakrabarti S, Adams PC. Inflammation is not the cause of an elevated serum ferritin in non-alcoholic fatty liver disease. Ann Hepatol353-6. PMID24756010
    14. Mortuza R, Feng B, Chakrabarti S. miR-195 regulates SIRT1-mediated changes in diabetic retinopathy. Diabetologia1037-46, doi:10.1007/s00125-014-3. PMID24570140.
    15. Zhao YZ, Tian XQ, Zhang M, Cai L, Ru A, Shen XT, Jiang X, Jin RR, Zheng L, Hawkins K, Chakrabarti S, Li XK, Lin Q, Yu WZ, Ge S, Lu CT, Wong HL. Functional and pathological improvements of the hearts in diabetes model by the combined therapy of bFGF-loaded nanoparticles with ultrasound-targeted microbubble destruction. J Control Release. 2014 Jul 28;186:22-31. doi:10.1016/j.jconrel.2014.04.054. Epub 2014 May 9. PMID24815422.
    16. Cao Y, Feng B, Chen S, Chu Y, Chakrabarti S. Mechanisms of endothelial to mesenchymal transition in the retina in diabetes. Investigative Ophthalmology Visual ScienceInvest Ophthalmol Vis Sci. 2014 Oct 21;55(11):7321-31. doi:10.1167/iovs.14-15167. PMID25335984.
    17. Zuo Y, Wu Y, Wehrli B, Chakrabarti S, Chakraborty C. Modulation of ERK5 Is a novel mechanism by which CDc42 Regulates Migration of Breast Cancer Cells. Journal Cell Biochemistry. doi:10.1002/jcb.24950. 
    18. Puthanveetil P, Thomas AA, Chakrabarti S. microRNAs in diabetes - are they perpetrators in disguise or just epiphenomena? Non-coding RNAs in Endocrinology. Volume 1, Issue 1, ISSN (Online) 2300-4258. doi:10.2478/micrnado-2014-0002, September 2014.
    19. Beaucage KL, Xiao A, Pollmann SI, Grol MW, Holdsworth DW, Sims SM, Darling MR, Dixon SJ. Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice. Purinergic Signalling 2014 Jun;10(2):291-304. doi:10.1007/s11302-013-9388-x. Epub 2013 Nov 13.  PMID24222214.
    20. Poon R, Su N, Ching V, Darling M, Grushka M. Reduction in unstimulated salivary flow rate in burning mouth syndrome. Br Dent J. 2014 Oct 10;217(7):E14. doi:10.1038/sj.bdj.2014.884. PMID25303607.
    21. Wilson A,  Delport J, Ponich T. Candida glabrata esophagitis: Are we seeing the emergence of a new azole-resistant pathogen?  International Journal of Microbiology. 2014;2014:371631. doi: 10.1155/2014/371631. Epub 2014 Dec 3
    22. Delport JA, John MA, Conkey B, MacDonald K, Lannigan R. Comparison of Direct Identification of Bacteria from VersaTrek Blood Culture Bottles Using a Seven Present Saponin Extraction Method and SepsiTyper by the Bruker MALDI-TOF. Int J Infect Dis. 2014 Apr; 21 (S1): 371.  DOI:  10.1016/j.ijid.2014.03.1186
    23. Anantha RV, Jegatheswaran J, Pepe DL, Priestap F, Delport J, Haeryfar SM, McCormick JK, Mele T. Risk Factors for Mortality Among Canadian Patients with Staphylococcus aureus Bacteremia: A Single Centre Retrospective Cohort Study. CMAJ Open. 2014 Oct: 2(4): E352-359. DOI: 10.9778/ cmajo.20140018.  eCollection 2014 Oct.  PMID:25553328
    24. Castonguay MC, Li-Chang HH, Driman DK. Venous invasion in oesophageal adenocarcinoma: enhanced detection using elastic stain and association with adverse histological features and clinical outcomes. Histopathology 693-700, doi:10.1111/his.12308. PMID24117900.
    25. Osmond A, Li-Chang H, Kirsch R, Divaris D, Falck V, Liu DF, Marginean C, Newell K, Parfitt J, Rudrick B, Sapp H, Smith S, Walsh J, Wasty F, Driman DK. Interobserver variability in assessing dysplasia and architecture in colorectal adenomas: a multicentre Canadian study. J Clin Pathol, doi:10.1136/jclinpath-20. PMID25004943.
    26. Rajakumar C, Vilos GA, Vilos AG, Marks JL, Ettler HC, Pautler SS. Combined Transurethral and Laparoscopic Partial Cystectomy and Robotically Assisted Bladder Repair for the Treatment of Bladder Endocervicosis: Case Report and Review of the Literature. J Obstet Gynaecol Can141-145. PMID24518913.
    27. Girgis H, Masui O, White NM, Scorilas A, Rotondo F, Seivwright A, Gabril M, Filter ER, Girgis AH, Bjarnason GA, Jewett MA, Evans A, Al-Haddad S, Siu KM, Yousef GM. Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma. Mol Cancer101 doi:10.1186/1476-4598-13. PMID24885701.
    28. Canadian Association of Pathologists Telepathology Guidelines Committee, Bernard C, Chandrakanth SA, Cornell IS, Dalton J, Evans A, Garcia BM, Godin C, Godlewski M, Jansen GH, Kabani A, Louahlia S, Manning L, Maung R, Moore L, Philley J, Slatnik J, Srigley J, Thibault A, Picard DD, Cracower H, Tetu B. Guidelines from the Canadian Association of Pathologists for establishing a telepathology service for anatomic pathology using whole-slide imaging. J Pathol Inform15, doi:10.4103/2153-3539.129455. eCollection 2014. PMID24843826.
    29. Wang H, Zhang Z, Tian W, Liu T, Han H, Fu Q, Garcia B, Li X. Memory T Cells Mediate Cardiac Allograft Vasculopathy and are Inactivated by Anti-OX40L Monoclonal Antibody. Cardiovasc Drugs Ther.2014; 28: 115-22. doi:10.1007/s10557-013-6502-9. PMID24254032.
    30. Palmer TD, Martínez CH, Vasquez C, Hebron KE, Jones-Paris C, Arnold SA, Chan SM, Chalasani V, Gomez-Lemus JA, Williams AK, Chin JL, Giannico GA, Ketova T, Lewis JD, Zijlstra A. Integrin-free tetraspanin CD151 can inhibit tumor cell motility upon clustering and is a clinical indicator of prostate cancer progression. Cancer Res173-87 doi:10.1158/0008-5472.CA. PMID24220242.
    31. Lau A, Khan K, Pavlosky A, Yin Z, Huang X, Haig A, Liu W, Singh B, Zhang ZX, Jevnikar AM. Serine Protease Inhibitor-6 Inhibits Granzyme B-Mediated Injury of Renal Tubular Cells and Promotes Renal Allograft Survival. Transplantation doi:10.1097/TP.000000000. PMID24918613.
    32. Lau A, Wang S, Liu W, Haig A, Zhang ZX, Jevnikar AM. Glycyrrhizic Acid Ameliorates HMGB1-Mediated Cell Death and Inflammation after Renal Ischemia Reperfusion Injury. Am J Nephrol84-95 doi:10.1159/000364908. PMID25059568.
    33. Rizek P, Cheung C, McLachlan RS, Hayman-Abello B, Lee DH, Hammond RR, Mirsattari SM. Childhood-onset nonprogressive chronic encephalitis. Epilepsy Behav. 2014 Feb;31:85-90 doi:10.1016/j.yebeh.2013. PMID24368410.
    34. Piorkowska K, Thompson JA, Nygard K, Matushewski B, Hammond RR, Richardson BS.   Synaptic Development and Neuronal Myelination are Altered with Growth Restriction in Fetal Guinea Pigs, Dev Neurosci, 2014;36(6):465-76. DOI: 10.1159/000363696. Epub 2014 Sep 26  PMID: 25277216
    35. Haust, MD, Gilber-Barness EF.  Founders of Pediatric Pathology: Remembering Dr Marie Valdes-Dapena.  Pediatric and Developmental Pathology 17, 165-168, 2014 doi: 10.2350/14-02-1442-PB.1
    36. Weinreb I, Piscuoglio S, Martelotto LG, Waggott D, Ng CK, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, da Cruz Paula A, Marchio C, Sakr RA, Lim R, Thompson LD, Chiosea SI, Seethala RR, Skalova A, Stelow EB, Fonseca I, Assaad A, How C, Wang J, de Borja R, Chan-Seng-Yue M, Howlett CJ, Nichols AC, Wen YH, Katabi N, Buchner N, Mullen L, Kislinger T, Wouters BG, Liu FF, Norton L, McPherson JD, Rubin BP, Clarke BA, Weigelt B, Boutros PC, Reis-Filho JS. Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. Nat Genet. 2014 Nov;46(11):1166-9 doi:10.1038/ng.3096. PMID25240283.
    37. Wong H, Watt C, Elsayed S, John M, Johnson G, Katz K, Krajden S, Lee C, Mazzulli T, Ostrowska K, Richardson D, Toye B, Vermeiren C, Yamamura D, and Simor AE. Characterization of Methicillin-Resistant Staphylococcus aureus Isolates From Patients with Persistent or Recurrent Bacteremia. Canadian Journal of Infectious Diseases & Medical MicrobiologyMarch/April 2014, Volume 25, Issue 2: 83-86.
    38. Lutz K, Hayward V, Joseph M, Wong E, Temple-Oberle C. Current biopsy practices for suspected melanomas: A Survey of Family Physicians in Southwestern Ontario. The Canadian Journal of Plastic Surgery, 22(3), 175-178.
    39. Kum JJY, Khan ZA. Propranolol inhibits growth of hemangioma-initiating cells but does not induce apoptosis. Pediatr Res75: 381-388, 2014 doi:10.1038/pr.2013.231. Epub 2013 Dec 2. PMID24296797.
    40. Keats EC, Dominguez JM, Grant MB, Khan ZA. Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced adipogenesis. Stem Cells32: 1649–1660, 2014 doi: 10.1002/stem.1659.  PMID24496952.
    41. Piccinin MA, Khan ZA. Pathophysiological role of enhanced bone marrow adipogenesis in diabetic complications. Adipocyte 3; 14-23, 2014 doi:10.4161/adip.32215.
    42. Cutz JC1, Craddock KJ, Torlakovic E, Brandao G, Carter RF, Bigras G, Deschenes J, Izevbaye I, Xu Z, Greer W, Yatabe Y, Ionescu D, Karsan A, Jung S, Fraser RS, Blumenkrantz M, Lavoie J, Fortin F, Bojarski A, Côté GB, van den Berghe JA, Rashid-Kolvear F, Trotter M, Sekhon HS, Albadine R, Tran-Thanh D, Gorska I, Knoll JH, Xu J, Blencowe B, Iafrate AJ, Hwang DM, Pintilie M, Gaspo R, Couture C, Tsao MS. Canadian Anaplastic Lymphoma Kinase Study: A Model for multicenter standardization and optimization of ALK testing in lung cancer. J Thoracic Oncology 9(9):1255-1263 doi:10.1097/JTO.0000000000000239  PMID25122422.
    43. Rogan PK, Li Y, Wickramasinghe A, Subasinghe A, Caminsky N, Khan W, Samarabandu J, Wilkins R, Flegal F, Knoll JH. Automating dicentric chromosome detection from cytogenetic biodosimetry data. Radiat Prot Dosimetry2014 Jun;159(1-4):95-104 doi:10.1093/rpd/ncu133. Epub 2014 Apr 21. PMID24757176.
    44. Khan WA, Rogan PK, Knoll JH

      Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes. 

      Mol Cytogenet. 2014 Nov 19;7(1):70. doi: 10.1186/s13039-014-0070-y. eCollection 2014. PMID: 25520753

    45. Owrangi AM, Lannigan R, Simonovic SP. Interaction between land-use change, flooding and human health in Metro Vancouver, Canada. Natural Hazards, Volume 72, Issue 2, June 2014, Pages 1219-1230
    46. Cancer Genome Atlas Research Network (affiliated with Ontario Tumour Bank: Bartlett JMS, Kodeeswara S, Parfitt J, Sekhon H, Albert M). Comprehensive molecular profiling of lung adenocarcinoma. Nature543-50 doi:10.1038/nature13385. PMID25079552.
    47. Sy K, Parfitt J, Marginean C, Riddell RH, Streutker CJ. Inflammatory pseudotumours of the esophagus. Histopathology. 2014 Nov 13. doi:10.1111/his.12615. [Epub ahead of print]. PMID25393329.
    48. Farhan SM, Wang J, Robinson JF, Lahiry P, Siu VM, Prasad C, Kronick JB, Ramsay DA, Rupar CA, Hegele RA. Exome sequencing identifies NFS1 deficiency in a novel Fe-S cluster disease, infantile mitochondrial complex II/III deficiency. Mol Genet Genomic Med 73-80 doi:10.1002/mgg3.46. PMID24498631.
    49. Prasad M, Narayan B, Prasad AN, Rupar CA, Levin S, Kronick J, Ramsay D, Tay KY, Prasad C. MELAS: A Multigenerational Impact of the MTTL1 A3243G MELAS Mutation. Can J Neurol Sci. 2014 Mar;41(2):210-9. PMID24534033.
    50. Cohen MC, Ramsay DA. "Shaken baby syndrome" and forensic pathology. Forensic Sci Med Pathol244-5 doi:10.1007/s12024-013-9. PMID24464795.
    51. Sangle NA, Schmidt RL, Patel JL, Jeffrey Medeiros L, Agarwal AM, Perkins SL, Salama ME. Optimized immunohistochemical panel to differentiate myeloid sarcoma from blastic plasmacytoid dendritic cell neoplasm. Mod Pathol.2014 Aug;27(8):1137-43. doi:10.1038/modpathol.2013.238. Epub 2014 Jan 3. PMID24390220.
    52. Layfield LJ, Schmidt RL, Sangle N, Crim JR. Diagnostic accuracy and clinical utility of biopsy in musculoskeletal lesions: a comparison of fine-needle aspiration, core, and open biopsy techniques. Diagn Cytopathol 2014 Jun;42(6):476-86. doi:10.1002/dc.23005. Epub 2014 Mar 19. PMID24644128.
    53. Jacques R, Kogon S, Shkrum M. An experimental model of tool mark striations by a serrated blade in human soft tissues. Am J Forensic Med Pathol59-61 doi:10.1097/PAF.00000000. PMID24457587.
    54. Bramwell VH, Tuck AB, Chapman JA, Anborgh PH, Postenka CO, Al-Katib W, Shepherd LE, Han L, Wilson CF, Pritchard KI, Pollak MN, Chambers AF. Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial. Breast Cancer ResR8 doi:10.1186/bcr3600. PMID24451146.
    55. Fok TC, Lapointe H, Tuck AB, Chambers AF, Jackson-Boeters L, Daley TD, Darling MR. Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin. Oral Surg Oral Med Oral Pathol Oral Radiol 320-9 doi:10.1016/j.oooo.2014. PMID25151586.
    56. MacMillan CD, Leong HS, Dales DW, Robertson AE, Lewis JD, Chambers AF, Tuck AB. Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway. Sci Rep6315 doi:10.1038/srep06315. PMID25204426.
    57. Lalani N, Paszat L, Sutradhar R, Thiruchelvam D, Nofech-Mozes S, Hanna W, Slodkowska E, Done SJ, Miller N, Youngson B, Tuck A, Sengupta S, Elavathil L, Chang MC, Jani PA, Bonin M, Rakovitch E. Long-term Outcomes of Hypofractionation Versus Conventional Radiation Therapy After Breast-Conserving Surgery for Ductal Carcinoma In Situ of the Breast. Int J Radiat Oncol Biol Phys doi:10.1016/j.ijrobp.201. PMID25220719.
    58. MacMillan CD, Leong HS, Dales DW, Robertson AE, Lewis JD, Chambers AF, Tuck AB. Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway. Scientific Reports, 4 : 6315 doi:10.1038/srep06315.
    59. O'Connor K, Walsh JC, Schaeffer DF.Combined hepatocellular-cholangiocarcinoma (cHCC-CC): a distinct entity. Ann Hepatol. 2014 May-Jun;13(3):317-22. PMID24756005.
    60. Schaeffer DF, Walsh JC, Kirsch R, Waterman M, Silverberg MS, Riddell RH.  Distinctive histopathologic phenotype in resection specimens from patients with Crohn's disease receiving anti-TNF-α therapy.  Hum Pathol. 2014 Sep;45(9):1928-35. DOI: 10.1016/j.humpath.2014.05.016. [Epub 2014 Jun 12.]  PMID: 25022570
    61. Ben-Bassat O, Tyler AD, Xu W, Kirsch R, Schaeffer DF, Walsh J, Steinhart AH, Greenberg GR, Cohen Z, Silverberg MS, McLeod RS.  Ileal pouch symptoms do not correlate with inflammation of the pouch.  Clin Gastroenterol Hepatol. 2014 May;12(5):831-837.e2. DOI: 10.1016/j.cgh.2013.09.027. [Epub 2013 Sep 27.]  PMID: 24075890
    62. Dowthwaite S, Szeto C, Wehrli B, Daley T, Whelan F, Franklin J, Nichols A, Yoo J, Fung K. Contact endoscopy as a novel technique in the detection and diagnosis of oral cavity and oropharyngeal mucosal lesions in the head and neck. J Laryngol Otol1-6 doi:10.1017/S00222151130. PMID24460932.
    63. Zuo Y, Wu Y, Wehrli B, Chakrabarti S, Chakraborty C. Modulation of ERK5 Is a Novel Mechanism by Which Cdc42 Regulates Migration of Breast Cancer Cells. J Cell Biochem doi:10.1002/jcb.24950. PMID25160664.
    64. Yeh DH, Wong J, Hoffbauer S, Wehrli B, Sommer D, Rotenberg BW. The utility of routine polyp histopathology after endoscopic sinus surgery. Int Forum Allergy Rhinol doi:10.1002/alr.21378.  PMID25142311.
    65. Zhang W, Xu X, Kao R, Mele T, Kvietys P, Martin CM, Rui T.  Cardiac fibroblasts contribute to myocardial dysfunction in mice with sepsis: the role of NLRP3 inflammasome activation. PLoS ONE 9(9): e107639. doi:10.1371/journal.pone.0107639
    66. Zhang X, Liu Y, Zhang G, Shi J, Zhang X, Zheng X, Jiang AT, Zhang ZX, Johnston N, Siu KS, Chen R, Lian D, Koos D, Quan D, Min WP. Synergic silencing of costimulatory molecules prevents cardiac allograft rejection. J Transl Med. 2014 May 22;12:142. doi: 10.1186/1479-5876-12-142.
    67. Chen D, Koropatnick J, Jiang N, Zheng X, Zhang X, Wang H, Yuan K,Siu KS, Shunnar A, Way C, Min WP. Targeted siRNA Silencing of Indoleamine 2, 3-Dioxygenase in Antigen-presenting Cells Using Mannose-conjugated Liposomes: A Novel Strategy for Treatment of Melanoma. J Immunother. 2014 Feb-Mar;37(2):123-34.
    68. Siu KS, Chen D, Zheng X, Zhang X, Johnston N, Liu Y, Yuan K, Koropatnick J, Gillies ER, Min WP. Non-covalently functionalized single-walled carbon nanotube for topical siRNA delivery into melanoma. Biomaterials 2014 Mar;35(10):3435-42.
    69. Chen K, Ablimit A, Ling F, Wu W, Shan W, Qin W, Keweier T, Zuo H, Zhang F, Ma Z, Zheng X. Paternal and maternal genetic analysis of a desert Keriyan population: Keriyans are not the descendants of Guge Tibetans. PLoS One. 2014 Jun 26;9(6):e100479.
    70. Shan W, Ablimit A, Zhou W, Zhang F, Ma Z, Zheng X. Genetic polymorphism of 17 Y chromosomal STRs in Kazakh and Uighur populations from Xinjiang, China. Int J Legal Med. 2014 Jan 8. [Epub ahead ofprint].
    71. Maleki Vareki S, Rytelewski M, Figueredo R, Chen D, Ferguson PJ, Vincent M, Min W, Zheng X, Koropatnick J. Indoleamine 2,3-dioxygenase mediates immune-independent human tumor cell resistance to olaparib, gamma radiation,and cisplatin. Oncotarget. 2014 May 15;5(9):2778-91.