Publications

publications

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2024 Publications

    1. Abdulrehman J, Forté S, Tomlinson G, Solh Z, Bolster L, Sun HL, Bartolucci P, Kuo KHM. THromboprophylaxis In Sickle Cell Disease with central venous catheters (THIS): an internal pilot randomised controlled trial protocol. BMJ Open. 2024 Jan 3;14(1):e079363. doi: 10.1136/bmjopen-2023-079363. PMID: 38171625
    2. Abou Taka M, Dugbartey GJ, Richard-Mohamed M, McLeod P, Jiang J, Major S, Arp J, O'Neil C, Liu W, Gabril M, Moussa M, Luke P, Sener A. Evaluating the Effects of Kidney Preservation at 10 °C with Hemopure and Sodium Thiosulfate in a Rat Model of Syngeneic Orthotopic Kidney Transplantation. Int J Mol Sci. 2024 Feb 12;25(4):2210. doi: 10.3390/ijms25042210. PMID: 38396887 
    3. Ahmad M, Chin-Yee B, Chin-Yee IH, Hedley B, Hsia CC. Laboratory reference intervals influence referral patterns for hemoglobin abnormalities in the Ontario virtual care system. PLOS Digit Health. 2024 Aug 21;3(8):e0000580. doi: 10.1371/journal.pdig.0000580. eCollection 2024 Aug. PMID: 39167626 
    4. Alkabie S, Gray MT, Lau JC, Barra L, Mandzia J, Zhang Q, Budhram A. Teaching NeuroImage: Unilateral Primary Angiitis of the CNS. Neurology. 2024 Jan 9;102(1):e208018. doi: 10.1212/WNL.0000000000208018. Epub 2023 Dec 13. PMID: 38175856
    5. Alkabie S, Murray BJ, Budhram A. Incidental Detection of Anti-IgLON5: A Diagnostic and Therapeutic Dilemma. Can J Neurol Sci. 2024 May;51(3):438-440. doi: 10.1017/cjn.2023.239. Epub 2023 May 26. PMID: 37230741 
    6. Almudhry M, Prasad C, Rupar CA, Tay KY, Prasad AN. Long-term follow-up of an attenuated presentation of NAXE-related disease, a potentially actionable neurometabolic disease: a case report. Front Neurol. 2024 Feb 14;15:1204848. doi: 10.3389/fneur.2024.1204848. eCollection 2024. PMID: 38419707
    7. Al-Naser Y, Halka F, Ng B, Mountford D, Sharma S, Niure K, Yong-Hing C, Khosa F, Van der Pol C. Evaluating Artificial Intelligence Competency in Education: Performance of ChatGPT-4 in the American Registry of Radiologic Technologists (ARRT) Radiography Certification Exam. Acad Radiol. 2024 Aug 16:S1076-6332(24)00572-5. doi: 10.1016/j.acra.2024.08.009. PMID: 39153961 
    8. Alphonsus L, De Silva TA, Driman D, Jairath V. Severe Ulcerative Colitis Complicated by Malakoplakia Resulting in Proctocolectomy. ACG Case Rep J. 2023 Jan 12;11(1):e01257. doi: 10.14309/crj.0000000000001257. eCollection 2024 Jan. PMID: 38222902
    9. Alturkustani M. Unraveling morphology, methylation profiling, and diagnostic challenges in BRAF-Mutant pediatric glial and glioneuronal tumors. Neurosciences (Riyadh). 2024. PMID: 38981632
    10. Andary CM, Al KF, Chmiel JA, Gibbons S, Daisley BA, Parvathy SN, Maleki Vareki S, Bowdish DME, Silverman MS, Burton JP. Dissecting mechanisms of fecal microbiota transplantation efficacy in disease. Trends Mol Med. 2024 Jan 8:S1471-4914(23)00284-8. doi: 10.1016/j.molmed.2023.12.005. PMID: 38195358 
    11. Avery EG, Zeppa JJ, Duncan DB, Barker KR, Fattouh R, Matukas LM, Rutherford C, Cabrera A, Sheth PM, Tran V, Goneau L, Katz K, Li XX, Kozak R. Evaluation of the utility and cost of secondary confirmatory testing for Neisseria gonorrhoeae identification from culture. Diagn Microbiol Infect Dis. 2024 Jul;109(3):116336. doi: 10.1016/j.diagmicrobio.2024.116336. Epub 2024 May 5. PMID: 38723452
    12. Awad SS, AbdelRahman A, Gabril M, Nageh K, Rezk AF. Immunohistochemical assessment of SOX10 and its relation to the immune cellular infiltrate in alopecia areata follicles. 2024 Journal of the Egyptian Women's Dermatologic Society, 21(3), pp. 187-192. doi: 10.4103/jewd.jewd_91_23. 
    13. Aziz SJ, Dickson BC, Lang P, Zeman CE. TLE1 Expression in NUT Carcinoma: A Case Report Highlighting a Potential Diagnostic Pitfall for the Pathologist. Int J Surg Pathol. 2024 Jan 17:10668969231217750. doi: 10.1177/10668969231217750. PMID: 38233028
    14. Bagherian E, Jokari S, Borjian Boroujeni P, Haratian K, Sabbaghian M, Mohseni Meybodi A. Role of genetic variations and protein expression of β-Microsemino protein in intrauterine insemination outcome of unexplained infertile men: A case-control study. Int J Reprod Biomed. 2024 Aug 5;22(6):481-494. doi: 10.18502/ijrm.v22i6.16799. eCollection 2024 Jun. PMID: 39205920 
    15. Blaney H, Díaz LA, Li N, Malhi G, Mortuza R, Qi X, Kulkarni AV, Bataller R, Cabezas J, Louvet A, Tapper EB, Arab JP. Global differences in the management of alcohol-associated hepatitis. Lancet Gastroenterol Hepatol. 2024 Sep 10:S2468-1253(24)00232-2. doi: 10.1016/S2468-1253(24)00232-2. PMID: 39270697 
    16. Boisclair M, Robitaille C, Budhram A, Kunchok A, Chapdelaine H, Létourneau-Guillon L, Macaron G, Larochelle C. Severe Relapsing Autoimmune Encephalitis with GABAA Receptor, Titin, and AchR Antibodies in a Patient with Thymoma: A Case Report. Case Rep Neurol. 2024 May 3;16(1):122-128. doi: 10.1159/000539186. eCollection 2024 Jan-Dec. PMID: 39015826 
    17. Bosch E, Güse E, Kirchner P, Winterpacht A, Walther M, Alders M, Kerkhof J, Ekici AB, Sticht H, Sadikovic B, Reis A, Vasileiou G. The missing link: ARID1B non-truncating variants causing Coffin-Siris syndrome due to protein aggregation. Hum Genet. 2024 Aug;143(8):965-978. doi: 10.1007/s00439-024-02688-9. Epub 2024 Jul 19. PMID: 39028335 
    18. Bouhamdani N, McConkey H, Leblanc A, Sadikovic B, Amor MB. Diagnostic utility of DNA methylation episignature analysis for early diagnosis of KMT2B-related disorders: case report. Front Genet. 2024 Feb 15;15:1346044. doi: 10.3389/fgene.2024.1346044. eCollection 2024. PMID: 38425714 
    19. Brandt AC, Abbas A, Dong CS. Exploring the acceptance of geriatric dentistry programming for undergraduate dental students through stakeholder interviews. J Dent Educ. 2024 Feb 6. doi: 10.1002/jdd.13461. PMID: 38321860
    20. Brandt AC, Lingard L, Dong CS. A multi-faceted construct to guide geriatric dental education: Findings from a scoping review with consultation. Gerodontology. 2024 Jun 14. doi: 10.1111/ger.12769. PMID: 38874011
    21. Branch A, Nuaaman MM, Appleton CT, Connaughton DM, Basmaji J, Chan TLH, Budhram A. Teaching NeuroImage: Extensive Brainstem and Striatal Involvement in Neuropsychiatric Systemic Lupus Erythematosus. 2024 Feb 27;102(4):e209153. doi: 10.1212/WNL.0000000000209153. Epub 2024 Jan 22. PMID: 38252913
    22. Budhram A. Exclusion of alternative diagnoses: A component of the 2023 MOGAD criteria that belongs at the forefront, not in the background. Mult Scler Relat Disord. 2024 Mar 7;85:105544. doi: 10.1016/j.msard.2024.105544. PMID: 38467091
    23. Budhram A, Flanagan EP.Optimizing the diagnostic performance of neural antibody testing for paraneoplastic and autoimmune encephalitis in clinical practice. Handb Clin Neurol. 2024;200:365-382. doi: 10.1016/B978-0-12-823912-4.00002-5. PMID: 38494290
    24. Budhram A, Sechi E. Antibodies to neural cell surface and synaptic proteins in paraneoplastic neurologic syndromes. Handb Clin Neurol. 2024;200:347-364. doi: 10.1016/B978-0-12-823912-4.00006-2. PMID: 38494289
    25. Budhram A, Rotstein DL, Yang L, Yeh EA. Myelin oligodendrocyte glycoprotein antibody titers by fixed cell-based assay: positive predictive value and impact of sample collection timing. Front Neurol. 2024 Mar 14;15:1380541. doi: 10.3389/fneur.2024.1380541. eCollection 2024. PMID: 38550339 
    26. Budhram A, Irani SR, Flanagan EP. Looking Beyond Syndrome-Based Criteria for Autoimmune Encephalitis-The Need for Complementary Neural Antibody-Based Diagnostic Criteria. JAMA Neurol. 2024 Mar 1;81(3):227-228. doi: 10.1001/jamaneurol.2023.4894. PMID: 38147324
    27. Bukvic N, De Rinaldis M, Chetta M, Trabacca A, Bassi MT, Marsano RM, Holoubkova L, Rivieccio M, Oro M, Resta N, Kerkhof J, Sadikovic B, Viggiano L. De Novo Pathogenic Variant in FBRSL1, Non OMIM Gene Paralogue AUTS2, Causes a Novel Recognizable Syndromic Manifestation with Intellectual Disability; An Additional Patient and Review of the Literature. Genes (Basel). 2024 Jun 22;15(7):826. doi: 10.3390/genes15070826. PMID: 39062605 
    28. Buss P, Miller M, Fuller A, Haw A, Thulson E, Olea-Popelka F, Meyer L. Effects of Butorphanol on Respiration in White Rhinoceros (Ceratotherium simum) Immobilized with Etorphine-Azaperone. J Wildl Dis. 2024 Jan 25. doi: 10.7589/JWD-D-23-00034. PMID: 38268196
    29. Chakrabarti R, Lin S, Wang H, Cecchini M. SMARCA4-Deficient Undifferentiated Tumor of the Esophagus: Diagnostic Pitfalls in Immunohistochemical Profiles. Int J Surg Pathol. 2024 Mar 18:10668969241228290. doi: 10.1177/10668969241228290. PMID: 38497146 
    30. Chang YC, Yang L, Budhram A. Positive predictive value of myositis antibody line blot testing in patients with suspected idiopathic inflammatory myopathy. Muscle Nerve. 2024 Feb 6. doi: 10.1002/mus.28050. PMID: 38321821
    31. Chang YC, Budhram A, Wong D. Anti-N-Methyl-D-Aspartate Receptor Encephalitis Triggered by Lyme Disease. Can J Neurol Sci. 2024 Mar;51(2):325-327. doi: 10.1017/cjn.2022.329. Epub 2022 Dec 1. PMID: 36451597
    32. Caraffi SG, van der Laan L, Rooney K, Trajkova S, Zuntini R, Relator R, Haghshenas S, Levy MA, Baldo C, Mandrile G, Lauzon C, Cordelli DM, Ivanovski I, Fetta A, Sukarova E, Brusco A, Pavinato L, Pullano V, Zollino M, McConkey H, Tartaglia M, Ferrero GB, Sadikovic B, Garavelli L. Identification of the DNA methylation signature of Mowat-Wilson syndrome. Eur J Hum Genet. 2024 Feb 13. doi: 10.1038/s41431-024-01548-4. PMID: 38351292
    33. Cima L, Bussola N, Hassell LA, Kiehl TR, Schukow C, Zerbe N, Munari E, Torresani E, Barbareschi M, Cecchini MJ, Cirielli V, Pagliuca F, Ahsan M, Mohanty SK, Arbitrio E, Hughes G, Mirza KM. Evolving educational landscape in pathology: a comprehensive bibliometric and visual analysis including digital teaching and learning resources. J Clin Pathol. 2024 Jan 18;77(2):87-95. doi: 10.1136/jcp-2023-209203. PMID: 38123966
    34. Chin-Yee B, Ho J, Sadikovic B, Chin-Yee I. Finding Goldilocks: Choosing Wisely Together in Hematology/Oncology. JCO Oncol Pract. 2024 Jan 8:OP2300604. doi: 10.1200/OP.23.00604. PMID: 38193724
    35. Daub M, Sangam K, Burneo JG, Budhram A. Low yield of routine cerebrospinal fluid analysis to assess for an autoimmune etiology in patients with chronic seizures of unknown cause. Can J Neurol Sci. 2024 Jun 4:1-9. doi: 10.1017/cjn.2024.276. PMID: 38831522
    36. Dear T, Chiu J, Meirovich H, Malkin A, Amjad R, D'Souza D, Callum J, Leung E, Kelly K, Lazo-Langner A, Solh Z. Are outcomes of locally advanced cervical cancer associated with prebrachytherapy hemoglobin values and transfusion practice? An observational study comparing two large academic centres with divergent clinical guidelines. Brachytherapy. 2024 Aug 27:S1538-4721(24)00119-3. doi: 10.1016/j.brachy.2024.07.006. PMID: 39198044
    37. Dias KR, Shrestha R, Schofield D, Evans CA, O'Heir E, Zhu Y, Zhang F, Standen K, Weisburd B, Stenton SL, Sanchis-Juan A, Brand H, Talkowski ME, Ma A, Ghedia S, Wilson M, Sandaradura SA, Smith J, Kamien B, Turner A, Bakshi M, Adès LC, Mowat D, Regan M, McGillivray G, Savarirayan R, White SM, Tan TY, Stark Z, Brown NJ, Pérez-Jurado LA, Krzesinski E, Hunter MF, Akesson L, Fennell AP, Yeung A, Boughtwood T, Ewans L, Kerkhof J, Lucas C, Carey L, French H, Rapadas M, Stevanovski I, Deveson IW, Cliffe C, Elakis G, Kirk EP, Dudding-Byth T, Fletcher J, Walsh R, Corbett MA, Kroes T, Gecz J, Meldrum C, Cliffe S, Wall M, Lunke S, North K, Amor DJ, Field M, Sadikovic B, Buckley MF, O'Donnell-Luria A, Roscioli T. Narrowing the Diagnostic Gap: Genomes, Episignatures, Long-Read Sequencing and Health Economic Analyses in an Exome-Negative Intellectual Disability Cohort. Genet Med. 2024 Jan 19:101076. doi: 10.1016/j.gim.2024.101076. PMID: 38258669
    38. Dong CS, Isings E, Jones SM, Samson H, McCorquodale L, Telfer TGW, Ropp T, Bell CE. Feedback and focus: Exploring post-secondary students’ perceptions of feedback, mindfulness, and stress. 2024 Cogent Education, 11(1), art. no. 2316920.
    39. England JT, Szuber N, Sirhan S, Dunne T, Cerquozzi S, Hill M, Villeneuve PJA, Ho JM, Sadikovic B, Bhai P, Krishnan N, Dowhanik S, Hillis C, Capo-Chichi JM, Tsui H, Cheung V, Gauthier K, Sibai H, Davidson MB, Bankar A, Kotchetkov R, Gupta V, Maze D. Clinical Features and Long-Term Outcomes of a Pan-Canadian Cohort of Adolescents and Young Adults with Myeloproliferative Neoplasms: A Canadian MPN Group Study. Leukemia. 2024 Mar;38(3):570-578. doi: 10.1038/s41375-024-02155-4. Epub 2024 Feb 6. PMID: 38321107
    40. Fan M, Song E, Zhang Y, Zhang P, Huang B, Yan K, Yang W, Chakrabarti S, Mahajan H, Yan S, Xu Y, Hua S, Liu W, Wang C, Xu A, Ye D. Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients: A Multicenter and Clinicopathological Study. Research (Wash D C). 2024 May 29;7:0382. doi: 10.34133/research.0382. eCollection 2024. PMID: 38812532 
    41. Fernández-Codina A, Nevskaya T, Baron M, Thomas Appleton C, Cecchini MJ, Philip A, El-Shimy M, Vanderhoek L, Pinal-Fernández I, Pope JE. Brentuximab vedotin for skin involvement in refractory diffuse cutaneous systemic sclerosis, an open-label trial. Rheumatology (Oxford). 2024 Apr 23:keae235. doi: 10.1093/rheumatology/keae235. PMID: 38652570
    42. Fernández-Codina A, Nevskaya T, Baron M, Appleton CT, Cecchini MJ, Philip A, El-Shimy M, Vanderhoek L, Pinal-Fernández I, Pope JE. Brentuximab vedotin compared to historical controls for severe skin involvement in cutaneous systemic sclerosis. Rheumatology (Oxford). 2024 Aug 27:keae460. doi: 10.1093/rheumatology/keae460. PMID: 39189988 
    43. Ferreira RC, Chato C, Baena LM, Palmer J, Olabode A, Champredon D, Poon A. Molecular epidemiology of viral infections. 2023 Molecular Medical Microbiology, Third Edition, pp. 2625-2639.
    44. Ferreira RC, Reynolds SJ, Capoferri AA, Baker OR, Brown EE, Klock E, Miller J, Lai J, Saraf S, Kirby C, Lynch B, Hackman J, Gowanlock SN, Tomusange S, Jamiru S, Anok A, Kityamuweesi T, Buule P, Bruno D, Martens C, Rose R, Lamers SL, Galiwango RM, Poon AFY, Quinn TC, Prodger JL, Redd AD. Temporary increase in circulating replication-competent latent HIV-infected resting CD4+ T cells after switch to an integrase inhibitor based antiretroviral regimen. EBioMedicine. 2024 Mar 4:105040. doi: 10.1016/j.ebiom.2024.105040. PMID: 38485563 
    45. Filler G, Ahmad F, Bhayana V, Díaz González de Ferris ME, Sharma AP. Limitations of U25 CKiD and CKD-EPI eGFR formulae in patients 2-20 years of age with measured GFR > 60 mL/min/1.73 m2-a cross-sectional study. Pediatr Nephrol. 2024 Apr;39(4):1169-1176. doi: 10.1007/s00467-023-06185-5. Epub 2023 Oct 16. PMID: 37840039
    46. Franco Lopez HD, Wehrli B , Macneil SD, Stewart P, Ezzat S, Van Uum, S. ACTH-Dependent Cushing Syndrome in Metastatic Acinic Cell Carcinoma: A Poor Prognostic. 2023 Annals of Internal Medicine Clinical Cases, 2(1), art. no. e220805.
    47. Fuhrmann B, Jiang J, Mcleod P, Huang X, Balaji S, Arp J, Diao H, Ma S, Peng T, Haig A, Gunaratnam L, Zhang ZX, Jevnikar AM. Inhibition of NK cell cytotoxicity by tubular epithelial cell expression of Clr-b and Clr-f. Curr Res Immunol. 2024 Jul 15;5:100081. doi: 10.1016/j.crimmu.2024.100081. eCollection 2024. PMID: 39113760 
    48. German RJ, Vuocolo B, Vossaert L, Saba L, Fletcher R, Tedder ML, Sadikovic B, Kerkhof J, Wangler M, Bacino CA; Texome Project. Recurrent carotid paragangliomas in a syndromic patient with a heterozygous missense variant in DNA Methyltransferase 3 Alpha. Am J Med Genet A. 2024 Aug 21:e63849. doi: 10.1002/ajmg.a.63849. PMID: 39166703
    49. Ghai S, Klotz L, Pond GR, Kebabdjian M, Downes MR, Belanger EC, Moussa M, van der Kwast TH. Comparison of Multiparametric MRI-targeted and Systematic Biopsies for Detection of Cribriform and Intraductal Carcinoma Prostate Cancer. Radiology. 2024 Jul;312(1):e231948. doi: 10.1148/radiol.231948. PMID: 39012252 
    50. Gill EE, Jia B, Murall CL, Poujol R, Anwar MZ, John NS, Richardsson J, Hobb A, Olabode AS, Lepsa A, Duggan AT, Tyler AD, N'Guessan A, Kachru A, Chan B, Yoshida C, Yung CK, Bujold D, Andric D, Su E, Griffiths EJ, Van Domselaar G, Jolly GW, Ward HKE, Feher H, Baker J, Simpson JT, Uddin J, Ragoussis J, Eubank J, Fritz JH, Gálvez JH, Fang K, Cullion K, Rivera L, Xiang L, Croxen MA, Shiell M, Prystajecky N, Quirion PO, Bajari R, Rich S, Mubareka S, Moreira S, Cain S, Sutcliffe SG, Kraemer SA, Joly Y, Alturmessov Y, Consortium C, Consortium C; VirusSeq Data Portal Academic and Health network; Fiume M, Snutch TP, Bell C, Lopez-Correa C, Hussin JG, Joy JB, Colijn C, Gordon PMK, Hsiao WWL, Poon AFY, Knox NC, Courtot M, Stein L, Otto SP, Bourque G, Shapiro BJ, Brinkman FSL. The Canadian VirusSeq Data Portal & Duotang: open resources for SARS-CoV-2 viral sequences and genomic epidemiology. ArXiv [Preprint]. 2024 May 8:arXiv:2405.04734v1. PMID: 38764594 
    51. Guccini F, Cantin MP, Thirunavukkarasu A, McKinley GP. Polymedia Literacy and Other Ethical Considerations for Online Ethnographic Research on Social Networking Sites. Ethics Hum Res. 2024 Sep-Oct;46(5):13-25. doi: 10.1002/eahr.500222. PMID: 39277876
    52. Haghshenas S, Bout HJ, Schijns JM, Levy MA, Kerkhof J, Bhai P, McConkey H, Jenkins ZA, Williams EM, Halliday BJ, Huisman SA, Lauffer P, de Waard V, Witteveen L, Banka S, Brady AF, Galazzi E, van Gils J, Hurst ACE, Kaiser FJ, Lacombe D, Martinez-Monseny AF, Fergelot P, Monteiro FP, Parenti I, Persani L, Simarro FS, Simpson BN; MKHK Research Consortium; Alders M, Robertson SP, Sadikovic B, Menke LA. Menke-Hennekam syndrome; delineation of domain-specific subtypes with distinct clinical and DNA methylation profiles. HGG Adv. 2024 Mar 28:100287. doi: 10.1016/j.xhgg.2024.100287. PMID: 38553851
    53. Haghshenas S, Karimi K, Stevenson RE, Levy MA, Relator R, Kerkhof J, Rzasa J, McConkey H, Lauzon-Young C, Balci TB, White-Brown AM, Carter MT, Richer J, Armour CM, Sawyer SL, Bhola PT, Tedder ML, Skinner CD, van Rooij IALM, van de Putte R, de Blaauw I, Koeck RM, Hoischen A, Brunner H, Esteki MZ, Pelet A, Lyonnet S, Amiel J, Boycott KM, Sadikovic B. Identification of a DNA methylation episignature for recurrent constellations of embryonic malformations. Am J Hum Genet. 2024 Aug 8;111(8):1643-1655. doi: 10.1016/j.ajhg.2024.07.005. Epub 2024 Jul 31. PMID: 39089258
    54. Haghshenas S, Putoux A, Reilly J, Levy MA, Relator R, Ghosh S, Kerkhof J, McConkey H, Edery P, Lesca G, Besson A, Coubes C, Willems M, Ruiz-Pallares N, Barat-Houari M, Tizzano EF, Valenzuela I, Sabbagh Q, Clayton-Smith J, Jackson A, O'Sullivan J, Bromley R, Banka S, Genevieve D, Sadikovic B. Discovery of DNA methylation signature in the peripheral blood of individuals with history of antenatal exposure to valproic acid. Genet Med. 2024 Jul 31;26(10):101226. doi: 10.1016/j.gim.2024.101226. PMID: 39097820
    55. Hahn C, McCombe JA, Budhram A. Response to: Management of Seizures and Epilepsy in patients with Autoimmune Encephalitis. Can J Neurol Sci. 2024 Apr 29:1-3. doi: 10.1017/cjn.2024.64. PMID: 38679921 
    56. Halari MM, Charyk Stewart T, McClafferty KJ, Pellar AC, Pickup MJ, Shkrum MJ. Injury patterns in motor vehicle collision-youth pedestrian deaths. Traffic Inj Prev. 2024;25(6):879-886. doi: 10.1080/15389588.2024.2351603. Epub 2024 Jun 20. PMID: 38900934
    57. Halvorson BD, Bao Y, Singh KK, Frisbee SJ, Hachinski V, Whitehead SN, Melling CWJ, Chantler PD, Goldman D, Frisbee JC. Thromboxane-induced cerebral microvascular rarefaction predicts depressive symptom emergence in metabolic disease. J Appl Physiol (1985). 2024 Jan 1;136(1):122-140. doi: 10.1152/japplphysiol.00410.2023. Epub 2023 Nov 16. PMID: 37969083
    58. Hanif F, Adeniyi A, Dorion R, Gomaa N, Jessani A. Impact of delayed dental treatment during the COVID-19 pandemic in an undergraduate dental clinic in Southwestern Ontario: A retrospective chart review. Journal of the Canadian Dental Association. 2024;90;01.
    59. Haratian K, Borjian Boroujeni P, Sabbaghian M, Maghareh Abed E, Moazenchi M, Mohseni Meybodi A. DEFB126 2-nt Deletion (rs11467417) as a Potential Risk Factor for Chlamydia Trachomatis Infection and Subsequent Infertility in Iranian Men. J Reprod Infertil. 2024 Jan-Mar;25(1):20-27. doi: 10.18502/jri.v25i1.15195. PMID: 39157277 
    60. Hillyer A, Quint A, Ghassemian A, Joh-Carnella N, Knauer MJ, Dawd D, Lazo-Langner A, Mangel J, Lam S, Abdoh H, Xenocostas A, Deotare U, Saini L, Foster C, Louzada M, Ho J, Chin-Yee I, Phua CW. Serologic Response to Vaccine for COVID-19 in Patients with Hematologic Malignancy: A Prospective Cohort Study. Clin Lymphoma Myeloma Leuk. 2024 Jan 18:S2152-2650(24)00021-1. doi: 10.1016/j.clml.2024.01.004. PMID: 38336492
    61. Hoogenboom A, Falix FA, van der Laan L, Kerkhof J, Alders M, Sadikovic B, van Haelst MM. Novel PUF60 variant suggesting an interaction between Verheij and Cornelia de Lange syndrome: phenotype description and review of the literature. Eur J Hum Genet. 2024 Jan 25. doi: 10.1038/s41431-023-01527-1. PMID: 38273166
    62. Huang SJY, Wang X, Halvorson BD, Bao Y, Frisbee SJ, Frisbee JC, Goldman D. Laser Doppler Fluximetry in Cutaneous Vasculature: Methods for Data Analyses. J Vasc Res. 2024 May 15:1-15. doi: 10.1159/000538718. PMID: 38749406
    63. Jayatilaka A, Winquist E, Lebiadowski-Parish J, Moulin DE, Cecchini M, Young S. Case - Long-term remission after repeated courses of palliative radiotherapy in a patient with metastatic MiT family translocation renal cell carcinoma. Can Urol Assoc J. 2024 May 21. doi: 10.5489/cuaj.8771. PMID: 39190179 
    64. Jeong J, Usman M, Li Y, Zhou XZ, Lu KP. Pin1-Catalyzed Conformation Changes Regulate Protein Ubiquitination and Degradation. Cells. 2024 Apr 23;13(9):731. doi: 10.3390/cells13090731. PMID: 38727267 
    65. Jin J, Wang Y, Liu Y, Chakrabarti S, Su Z. Cardiac resident macrophages: Spatiotemporal distribution, development, physiological functions, and their translational potential on cardiac diseases. Acta Pharm Sin B. 2024 Apr;14(4):1483-1493. doi: 10.1016/j.apsb.2023.12.018. Epub 2024 Jan 2.PMID: 38572111 
    66. Kankaka EN, Poon AFY, Quinn TC, Chang LW, Prodger JL, Redd AD. Impact of variable sampling on estimates of HIV-1 reservoir formation dates. J Infect Dis. 2024 May 31:jiae294. doi: 10.1093/infdis/jiae294. PMID: 38819322
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    117. Singh S, Zhong S, Rogers K, Hachinski V, Frisbee S. Corrigendum: Prioritizing determinants of cognitive function in healthy middle-aged and older adults: insights from a machine learning regression approach in the Canadian longitudinal study on aging. Front Public Health. 2024 Feb 12;12:1372914. doi: 10.3389/fpubh.2024.1372914. eCollection 2024. PMID: 38410659 
    118. Singh S, Goodwin S, Zhong S, Avan A, Rogers K, Hachinski V, Frisbee S. Inequalities in health-related quality of life and functional health of an aging population: A Canadian community perspective. PLoS One. 2024 Jul 5;19(7):e0304457. doi: 10.1371/journal.pone.0304457. eCollection 2024. PMID: 38968188 
    119. Smith KM, Budhram A, Geis C, McKeon A, Steriade C, Stredny CM, Titulaer MJ, Britton JW. Autoimmune-associated seizure disorders. Epileptic Disord. 2024 May 31. doi: 10.1002/epd2.20231. PMID: 38818801
    120. Stewart R, Sharma S, Wu T, Okuda S, Xie G, Zhou XZ, Shilton B, Lu KP. The role of the master cancer regulator Pin1 in the development and treatment of cancer. Front Cell Dev Biol. 2024 Apr 30;12:1343938. doi: 10.3389/fcell.2024.1343938. eCollection 2024. PMID: 38745861
    121. Strong MJ, McLellan C, Kaplanis B, Droppelmann CA, Junop M. Phase Separation of SARS-CoV-2 Nucleocapsid Protein with TDP-43 Is Dependent on C-Terminus Domains. Int J Mol Sci. 2024 Aug 12;25(16):8779. doi: 10.3390/ijms25168779. PMID: 39201466 
    122. Stevic I, Singh H, Sokoro A. Feasibility of opportunistic colorectal cancer screening of hospitalized patients in tertiary care and community hospitals. Lab Med. 2024 Apr 5:lmae021. doi: 10.1093/labmed/lmae021. PMID: 38578655
    123. Sutcliffe SG, Kraemer SA, Ellmen I, Knapp JJ, Overton AK, Nash D, Nissimov JI, Charles TC, Dreifuss D, Topolsky I, Baykal PI, Fuhrmann L, Jablonski KP, Beerenwinkel N, Levy JI, Olabode AS, Becker DG, Gugan G, Brintnell E, Poon AFY, Valieris R, Drummond RD, Defelicibus A, Dias-Neto E, Rosales RA, Tojal da Silva I, Orfanou A, Psomopoulos F, Pechlivanis N, Pipes L, Chen Z, Baaijens JA, Baym M, Shapiro BJ. Tracking SARS-CoV-2 variants of concern in wastewater: an assessment of nine computational tools using simulated genomic data. Microb Genom. 2024 May;10(5):001249. doi: 10.1099/mgen.0.001249. PMID: 38785221 
    124. Tian R, Wang E, Sivasubramaniam P, Baskota SU, Sharma A, Cecchini MJ. Ten Years of Pathology on Twitter (X): Landscape and Evolution of Pathology on Twitter From 2012 to 2023. Arch Pathol Lab Med. 2024 Apr 11. doi: 10.5858/arpa.2023-0447-OA. PMID: 38599590 
    125. Topham JJ, Wehrli B, Kadar A. Idiopathic avascular necrosis of the scaphoid (Preiser's disease): a case report and review of the literature. Case Reports Plast Surg Hand Surg. 2024 Jul 4;11(1):2374550. doi: 10.1080/23320885.2024.2374550. eCollection 2024. PMID: 38974171 
    126. Torlakovic EE, Baniak N, Barnes PJ, Chancey K, Chen L, Cheung C, Clairefond S, Cutz JC, Faragalla H, Gravel DH, Dakin Hache K, Iyengar P, Komel M, Kos Z, Lacroix-Triki M, Marolt MJ, Mrkonjic M, Mulligan AM, Nofech-Mozes S, Park PC, Plotkin A, Raphael S, Rees H, Seno HR, Thai DV, Troxell ML, Varma S, Wang G, Wang T, Wehrli B, Bigras G. Fit-for-Purpose Ki-67 Immunohistochemistry Assays for Breast Cancer. Lab Invest. 2024 May 9;104(7):102076. doi: 10.1016/j.labinv.2024.102076. PMID: 38729353
    127. Trajkova S, Kerkhof J, Rossi Sebastiano M, Pavinato L, Ferrero E, Giovenino C, Carli D, Di Gregorio E, Marinoni R, Mandrile G, Palermo F, Carestiato S, Cardaropoli S, Pullano V, Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, Christopher EA, DeTure M, Seeley WW, Lee EB, Frosch MP, Molina-Porcel L, Gefen T, Redding-Ochoa J, Ghetti B, Robinson AC, Kobylecki C, Rowe JB, Beach TG, Teich AF, Keith JL, Bodi I, Halliday GM, Gearing M, Arzberger T, Morris CM, White CL 3rd, Mechawar N, Boluda S, MacKenzie IR, McLean C, Cykowski MD, Wang SJ, Graff C, Nagra RM, Kovacs GG, Giaccone G, Neumann M, Ang LC, Carvalho A, Morris HR, Rademakers R, Hardy JA, Dickson DW, Rohrer JD, Ross OA; Pick's disease International Consortium. MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study. Lancet Neurol. 2024 May;23(5):487-499. doi: 10.1016/S1474-4422(24)00083-8. PMID: 38631765 
    128. van der Laan L, Karimi K, Rooney K, Lauffer P, McConkey H, Caro P, Relator R, Levy MA, Bhai P, Mignot C, Keren B, Briuglia S, Sobering AK, Li D, Vissers LELM, Dingemans AJM, Valenzuela I, Verberne EA, Misra-Isrie M, Zwijnenburg PJG, Waisfisz Q, Alders M, Sailer S, Schaaf CP, Mannens MMAM, Sadikovic B, van Haelst MM, Henneman P. DNA methylation episignature, extension of the clinical features, and comparative epigenomic profiling of Hao-Fountain syndrome caused by variants in USP7. Genet Med. 2023 Dec 18;26(3):101050. doi: 10.1016/j.gim.2023.101050. PMID: 38126281
    129. van der Laan L, Lauffer P, Rooney K, Silva A, Haghshenas S, Relator R, Levy MA, Trajkova S, Huisman SA, Bijlsma EK, Kleefstra T, van Bon BW, Baysal Ö, Zweier C, Palomares-Bralo M, Fischer J, Szakszon K, Faivre L, Piton A, Mesman S, Hochstenbach R, Elting MW, van Hagen JM, Plomp AS, Mannens MMAM, Alders M, van Haelst MM, Ferrero GB, Brusco A, Henneman P, Sweetser DA, Sadikovic B, Vitobello A, Menke LA. DNA methylation episignature and comparative epigenomic profiling for Pitt-Hopkins syndrome caused by TCF4 variants. HGG Adv. 2024 Apr 2:100289. doi: 10.1016/j.xhgg.2024.100289. PMID: 38571311 
    130. Verma S, Chapman A, Pickard LA, Porplycia D, McConkey H, Jarosz P, Sinfield J, Lauzon-Young C, Cecchini M, Howlett C, Grindrod N, Sadikovic B, Welch SA, Breadner D. Evaluation of HER2 immunohistochemistry expression in nonstandard solid tumors from a Single-Institution Prospective Cohort. 2024 Exploration of Targeted Anti-tumor Therapy, 5(5), pp. 1100-1109. doi: 10.37349/etat.2024.00265
    131. Vos N, Haghshenas S, van der Laan L, Russel PKM, Rooney K, Levy MA, Relator R, Kerkhof J, McConkey H, Maas SM, Vissers LELM, de Vries BBA, Pfundt R, Elting MW, van Hagen JM, Verbeek NE, Jongmans MCJ, Lakeman P, Rumping L, Bosch DGM, Vitobello A, Thauvin-Robinet C, Faivre L, Nambot S, Garde A, Willems M, Genevieve D, Nicolas G, Busa T, Toutain A, Gérard M, Bizaoui V, Isidor B, Merla G, Accadia M, Schwartz CE, Ounap K, Hoffer MJV, Nezarati MM, van den Boogaard MH, Tedder ML, Rogers C, Brusco A, Ferrero GB, Spodenkiewicz M, Sidlow R, Mussa A, Trajkova S, McCann E, Mroczkowski HJ, Jansen S, Donker-Kaat L, Duijkers FAM, Stuurman KE, Mannens MMAM, Alders M, Henneman P, White SM, Sadikovic B, van Haelst MM. The detection of a strong episignature for Chung-Jansen syndrome, partially overlapping with Börjeson-Forssman-Lehmann and White-Kernohan syndromes. Hum Genet. 2024 May 24. doi: 10.1007/s00439-024-02679-w. PMID: 38787418
    132. Wang AY, Lin S, Tran C, Homer RJ, Wilsdon D, Walsh JC, Goebel EA, Sansano I, Sonawane S, Cockenpot V, Mukhopadhyay S, Taskin T, Zahra N, Cima L, Semerci O, Özamrak BG, Mishra P, Vennavalli NS, Chen PC, Cecchini MJ. Assessment of Pathology Domain-Specific Knowledge of ChatGPT and Comparison to Human Performance. Arch Pathol Lab Med. 2024 Jan 20. doi: 10.5858/arpa.2023-0296-OA. PMID: 38244054 
    133. Wang H, Wang EZR, Feng B, Chakrabarti S. CircRNA_012164/MicroRNA-9-5p axis mediates cardiac fibrosis in diabetic cardiomyopathy. PLoS One. 2024 Jul 23;19(7):e0302772. doi: 10.1371/journal.pone.0302772. eCollection 2024. PMID: 39042659 
    134. Win PW, Nyugen J, Morin AL, Newcomb CE, Singh SM, Gomaa N, Castellani CA. Simultaneous assessment of mitochondrial DNA copy number and nuclear epigenetic age towards predictive models of development and aging. BMC Res Notes. 2024 Jan 11;17(1):21. doi: 10.1186/s13104-023-06673-9. PMID: 38212867 
    135. Yang J, Chen L, Liu E, Wang B, Driman DK, Zhang Q, Ling C. Deep learning system for true- and pseudo-invasion in colorectal polyps. Sci Rep. 2024 Jan 3;14(1):426. doi: 10.1038/s41598-023-50681-5. PMID: 38172166 
    136. Yousefi Y, Baines KJ, Maleki Vareki S. Microbiome bacterial influencers of host immunity and response to immunotherapy. Cell Rep Med. 2024 Mar 21:101487. doi: 10.1016/j.xcrm.2024.101487. PMID: 38547865 
    137. Zeng PYF, Prokopec SD, Lai SY, Pinto N, Chan-Seng-Yue MA, Clifton-Bligh R, Williams MD, Howlett CJ, Plantinga P, Cecchini MJ, Lam AK, Siddiqui I, Wang J, Sun RX, Watson JD, Korah R, Carling T, Agrawal N, Cipriani N, Ball D, Nelkin B, Rooper LM, Bishop JA, Garnis C, Berean K, Nicolson NG, Weinberger P, Henderson YC, Lalansingh CM, Tian M, Yamaguchi TN, Livingstone J, Salcedo A, Patel K, Vizeacoumar F, Datti A, Xi L, Nikiforov YE, Smallridge R, Copland JA, Marlow LA, Hyrcza MD, Delbridge L, Sidhu S, Sywak M, Robinson B, Fung K, Ghasemi F, Kwan K, MacNeil SD, Mendez A, Palma DA, Khan MI, Shaikh M, Ruicci KM, Wehrli B, Winquist E, Yoo J, Mymryk JS, Rocco JW, Wheeler D, Scherer S, Giordano TJ, Barrett JW, Faquin WC, Gill AJ, Clayman G, Boutros PC, Nichols AC. The genomic and evolutionary landscapes of anaplastic thyroid carcinoma. Cell Rep. 2024 Feb 26;43(3):113826. doi: 10.1016/j.celrep.2024.113826. PMID: 38412093 
    138. Zhang KK, Rupar CA, Prasad C. Severe Developmental Delay and Behavior Abnormalities in a Patient with De Novo CAMK2B Mutation: A Case Report and Literature Review. Ann Indian Acad Neurol. 2024 Jul 1;27(4):430-434. doi: 10.4103/aian.aian_118_24. Epub 2024 Aug 8. PMID: 39113374 
    139. Zheng X. circITGa9: A Novel Therapeutic Target for Cardiac Diseases. Research (Wash D C). 2024 Feb 16;7:0312. doi: 10.34133/research.0312. eCollection 2024. PMID: 38371272
    140. Zhou RW, Sangam K, Budhram A. Clinical Utility of CSF Correction Factors for Traumatic Lumbar Puncture in Adults. Neurol Clin Pract. 2024 Dec;14(6):e200350. doi: 10.1212/CPJ.0000000000200350. Epub 2024 Aug 16. PMID: 39185100 

2023 Publications

    1. Ahmad M, Chin-Yee B, Sangle N, Rizkalla K, Chin-Yee I, Hsia CC. Pericardial Extramedullary Hematopoiesis Associated with Metastatic Adenocarcinoma of Gastrointestinal or Pancreaticobiliary Origin: A Case Report. Case Rep Oncol. 2023 Feb 17;16(1):96-101. doi: 10.1159/000529123. eCollection 2023 Jan-Dec. PMID: 36820213
    2. Al Harthy T, Colaiacovo S, Gratton RJ, Coughlin K, Siu VM, Prasad C, Rupar C, Saleh M. Dual diagnosis of trisomy 21 and lethal perinatal Gaucher disease as a cause of non-immune hydrops fetalis in a twin pregnancy for a consanguineous couple. Clin Case Rep. 2023 Aug 23;11(8):e7827. doi: 10.1002/ccr3.7827. eCollection 2023 Aug. PMID: 37637203 
    3. Alkabie S, Budhram A. Prolonged Corticosteroids Without Maintenance Immunotherapy for Treatment of Anti-LGI1 Encephalitis: Analysis of Outcomes and Relapse Rate. Neurol Neuroimmunol Neuroinflamm. 2023 Apr 4;10(3):e200115. doi: 10.1212/NXI.0000000000200115. Print 2023 May. PMID: 37015827 
    4. Alkabie S, Yang L, Budhram A. Neural antibody testing for autoimmune encephalitis: Impact of Autoimmune Neurology approval process on test utilization. J Neurol Sci. 2023 Jul 15;450:120676. doi: 10.1016/j.jns.2023.120676. Epub 2023 May 9. PMID: 37209510
    5. Alkabie S, Murray BJ, Budhram A. Incidental Detection of Anti-IgLON5: A Diagnostic and Therapeutic Dilemma. Can J Neurol Sci. 2023 May 26:1-7. doi: 10.1017/cjn.2023.239. PMID: 37230741 
    6. AlMutawa F, Kim SH, Cabrera A, Delport J. Yokenella regensburgei infection in an immunocompetent individual after trauma following a fall from a personal conveyance. J Assoc Med Microbiol Infect Dis Can. 2023 Mar 1;8(1):94-98. doi: 10.3138/jammi-2022-0018. eCollection 2023 Mar. PMID: 37008588 
    7. AlMutawa F, Cabrera A, Chen F, Delport J. Performance of MassARRAY system for the detection of SARS-CoV-2 compared to real-time PCR. Eur J Microbiol Immunol (Bp). 2023 Jun 15. doi: 10.1556/1886.2023.00013. PMID: 37318958
    8. Anazodo UC, Wong DY, Théberge J, Dacey M, Gomes J, Penny JD, Van Ginkel M, Poirier SE, McIntyre CW. Hemodialysis-Related Acute Brain Injury Demonstrated by Application of Intradialytic Magnetic Resonance Imaging and Spectroscopy. J Am Soc Nephrol. 2023 Mar 9. doi: 10.1681/ASN.0000000000000105. PMID: 36890644
    9. AlMutawa FCabrera A, Chen F, Delport J. Performance of MassARRAY system for the detection of SARS-CoV-2 compared to real-time PCR. Eur J Microbiol Immunol (Bp). 2023 Jun 15;13(1):1-5. doi: 10.1556/1886.2023.00013. Print 2023 Jul 7. PMID: 37318958
    10. Alturkustani M. Diagnostic Insights into Pediatric Pleomorphic Xanthoastrocytoma through DNA Methylation Class and Pathological Diagnosis Analysis. Diagnostics (Basel). 2023 Nov 17;13(22):3464. doi: 10.3390/diagnostics13223464. PMID: 37998600 
    11. Arteaga DP, DeKraker C, Ennis M, Dewey N, Goebel EA, Welch S, Pimentel I, Ippolito JE, Lohmann AE. Body composition and endometrial cancer outcomes. J Natl Cancer Inst Monogr. 2023 May 4;2023(61):49-55. doi: 10.1093/jncimonographs/lgad012. PMID: 37139979
    12. Baird T, Kirpalani A, Knauer M, Plouffe B, Abdulsatar F. Severe rhabdomyolysis temporally associated with SARS-CoV-2 vaccine in an adolescent: a case report. 2023 Pediatric Medicine, 6, art. no. 30.  
    13. Baranova K, Driman DK. Staying Online in Uncertain Times: A Nationwide Canadian Survey of Pathology Resident Uses of and Adaptations to Online Learning During COVID-19. Arch Pathol Lab Med. 2023 Nov 1;147(11):1333-1339. doi: 10.5858/arpa.2022-0208-EP. PMID: 36656172 
    14. Becker D, Champredon D, Chato C, Gugan G, Poon A. SUP: a probabilistic framework to propagate genome sequence uncertainty, with applications. NAR Genom Bioinform. 2023 Apr 24;5(2):lqad038. doi: 10.1093/nargab/lqad038. eCollection 2023 Jun. PMID: 37101658 
    15. Bell KA, Kim R, Aronson M, Gillies B, Ali Awan A, Chun K, Hart J, Healey R, Kim L, Klaric G, Panabaker K, Sabatini PJB, Sadikovic B, Selvarajah S, Smith AC, Stockley TL, Vaags AK, Eisen A, Pollett A, Feilotter H. Development of a comprehensive approach to adult hereditary cancer testing in Ontario. J Med Genet. 2023 Aug;60(8):769-775. doi: 10.1136/jmg-2022-108945. Epub 2022 Dec 23. PMID: 36564171
    16. Bessemer RA, Tay KY, Budhram A. Teaching NeuroImage: Hyperglycemia-Induced Occipital Lobe Seizures. Neurology. 2023 Apr 25:10.1212/WNL.0000000000207373. doi: 10.1212/WNL.0000000000207373. PMID: 37185120
    17. Bhai P, Turowec J, Santos S, Kerkhof J, Pickard L, Foroutan A, Breadner D, Cecchini M, Levy MA, Stuart A, Welch S, Howlett C, Lin H, Sadikovic B. Molecular profiling of solid tumors by next-generation sequencing: an experience from a clinical laboratory. Front Oncol. 2023 Jul 6;13:1208244. doi: 10.3389/fonc.2023.1208244. eCollection 2023. PMID: 37483495 
    18. Blackler G, Akingbasote J, Cairns E, Howlett C, Kiser P, Barra L. The effect of HLA-DRB1*04:01 on a mouse model of atherosclerosis. J Transl Autoimmun. 2023 Jun 21;7:100203. doi: 10.1016/j.jtauto.2023.100203. eCollection 2023 Dec. PMID: 37408614 
    19. Bogaert E, Garde A, Gautier T, Rooney K, Duffourd Y, LeBlanc P, van Reempts E, Tran Mau-Them F, Wentzensen IM, Au KS, Richardson K, Northrup H, Gatinois V, Geneviève D, Louie RJ, Lyons MJ, Laulund LW, Brasch-Andersen C, Maxel Juul T, El It F, Marle N, Callier P, Relator R, Haghshenas S, McConkey H, Kerkhof J, Cesario C, Novelli A, Brunetti-Pierri N, Pinelli M, Pennamen P, Naudion S, Legendre M, Courdier C, Trimouille A, Fenzy MD, Pais L, Yeung A, Nugent K, Roeder ER, Mitani T, Posey JE, Calame D, Yonath H, Rosenfeld JA, Musante L, Faletra F, Montanari F, Sartor G, Vancini A, Seri M, Besmond C, Poirier K, Hubert L, Hemelsoet D, Munnich A, Lupski JR, Philippe C, Thauvin-Robinet C, Faivre L, Sadikovic B, Govin J, Dermaut B, Vitobello A. SRSF1 haploinsufficiency is responsible for a syndromic developmental disorder associated with intellectual disability. Am J Hum Genet. 2023 May 4;110(5):790-808. doi: 10.1016/j.ajhg.2023.03.016. Epub 2023 Apr 17. PMID: 37071997
    20. Bohn MK, Nichols M, Yang LBhayana V, Macri J, Adeli K. Pediatric Reference Value Profiling of Essential Trace and Toxic Elements in Healthy Children and Adolescents Using High-Resolution and Triple Quadrupole Inductively Coupled Plasma Mass Spectrometry. J Appl Lab Med. 2023 May 19:jfad019. doi: 10.1093/jalm/jfad019. PMID: 37207688
    21. Boroujeni PB, Rooney K, Alikhani M, Rahmati S, Feli G, Haratian K, Movaghar B, Meybodi AM. Evaluation of TUBB8 gene alterations in infertile women with oocyte maturation and cleavage arrest referred to Royan Institute. Reprod Biomed Online. 2023 May 3;47(4):103226. doi: 10.1016/j.rbmo.2023.04.017. PMID: 37597348
    22. Budhram A. Fixed cell-based assays for autoantibody detection in myasthenia gravis: a diagnostic breakthrough. Lancet Reg Health West Pac. 2023 Aug 9;38:100876. doi: 10.1016/j.lanwpc.2023.100876. eCollection 2023 Sep. PMID: 37601007
    23. Budhram A, Freeman E, Bhayana VYang L. Positive Predictive Value of Anti-GAD65 ELISA Cut-Offs for Neurological Autoimmunity. Can J Neurol Sci. 2023 Sep;50(5):766-768. doi: 10.1017/cjn.2022.276. Epub 2022 Jul 21. PMID: 35861111
    24. Budhram A, Burneo JG. Acute symptomatic seizures, epilepsy, and autoimmune encephalitis: Clarifying terminology in neural antibody-associated disease. Epilepsia. 2023 Feb;64(2):306-310. doi: 10.1111/epi.17478. Epub 2022 Dec 24. PMID: 36471647 
    25. Budhram A, Irani SR, Flanagan EP. Looking Beyond Syndrome-Based Criteria for Autoimmune Encephalitis-The Need for Complementary Neural Antibody-Based Diagnostic Criteria. JAMA Neurol. 2023 Dec 26. doi: 10.1001/jamaneurol.2023.4894. PMID: 38147324
    26. Bukvic N, Chetta M, Bagnulo R, Leotta V, Pantaleo A, Palumbo O, Palumbo P, Oro M, Rivieccio M, Laforgia N, De Rinaldis M, Rosati A, Kerkhof J, Sadikovic B, Resta N. What Have We Learned from Patients Who Have Arboleda-Tham Syndrome Due to a De Novo KAT6A Pathogenic Variant with Impaired Histone Acetyltransferase Function? A Precise Clinical Description May Be Critical for Genetic Testing Approach and Final Diagnosis. Genes (Basel). 2023 Jan 7;14(1):165. doi: 10.3390/genes14010165. PMID: 36672906
    27. Burm S, Deagle S, Watling CJ, Wylie L, Alcock D. Navigating the burden of proof and responsibility: A narrative inquiry into Indigenous medical learners' experiences. Med Educ. 2023 Jun;57(6):556-565. doi: 10.1111/medu.15000. Epub 2022 Dec 29. PMID: 36495548
    28. Buzea C, Pacheco I. State-of-the-art of polymer/fullerene nanocomposites in biomedical fields, chapter 9 in the book: Fullerenes in Polymers: Design to Versatile Applications, Edited by Dr. Ayesha Kausar, Elsevier January 10, 2023, Paperback ISBN: 9780323995153, eBook ISBN: 9780323995160
    29. Buzea C, Pacheco I. Gold and silver nanoparticles: properties and toxicity, chapter 2 in the book: Gold and silver nanoparticles: Synthesis and applications. Micro and Nanotechnologies book series, Edited by Suban K. Sahoo, M. Reza Hormozi-Nezhad, Elsevier January 20, 2023, ISBN: 9780323994545, pp. 59-82.
    30. Cabrera A, Al Mutawah F, Kadour M, Schofield S, Conkey B, Fuller J, Payne M, Elsayed S, Delport J. Increasing SARS-CoV-2 testing capacity through specimen pooling: An acute care center experience. PLoS One. 2023 Jun 28;18(6):e0267137. doi: 10.1371/journal.pone.0267137. eCollection 2023. PMID: 37379564
    31. Cao T, Ni R, Ding W, Ji X, Fan GC, Zhang Z, Peng T. Nicotinamide mononucleotide as a therapeutic agent to alleviate multi-organ failure in sepsis. J Transl Med. 2023 Dec 6;21(1):883. doi: 10.1186/s12967-023-04767-3. PMID: 38057866 
    32. Chandna N, Budhram A, Blanchette PS, Climans SA. Paraneoplastic Anti-Neuronal Nuclear Antibody Type 3 Neurologic Autoimmunity. Can J Neurol Sci. 2023 Dec 27:1-3. doi: 10.1017/cjn.2023.324. PMID: 38148003 
    33. Charyk Stewart T, Lakha N, Milton L, Bérubé M. Current trauma team activation processes at Canadian trauma centres: A national survey. Injury. 2024 Jan;55(1):111220. doi: 10.1016/j.injury.2023.111220. Epub 2023 Nov 17. PMID: 38012901
    34. Charyk Stewart T, Unni P, Hanson HR, Gilliland J, Clark A, Fraser DD. Pivoting injury prevention efforts during a pandemic: results of an international survey. Inj Epidemiol. 2023 Nov 16;10(Suppl 1):59. doi: 10.1186/s40621-023-00472-3. PMID: 37974235 
    35. Chen R, Zhang S, Liu F, Xia L, Wang C, Sandoghchian Shotorbani S, Xu H, Chakrabarti S, Peng T, Su Z. Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation via Jagged-1-Notch1. Acta Pharm Sin B. 2023 Jan;13(1):128-141. doi: 10.1016/j.apsb.2022.08.016. Epub 2022 Aug 27. PMID: 36815032
    36. Chretien ML, Bailey DG, Asher L, Parfitt J, Driman D, Gregor J, Dresser GK. Severity of coeliac disease and clinical management study when using a non-metabolised medication: a phase I pharmacokinetic study. BMJ Open. 2023 Feb 24;13(2):e057151. doi: 10.1136/bmjopen-2021-057151. PMID: 36828648
    37. Christensen E, Luo P, Turinsky A, Husić M, Mahalanabis A, Naidas A, Diaz-Mejia JJ, Brudno M, Pugh T, Ramani A, Shooshtari P. Evaluation of single-cell RNAseq labelling algorithms using cancer datasets. Brief Bioinform. 2023 Jan 19;24(1):bbac561. doi: 10.1093/bib/bbac561. PMID: 36585784 
    38. Connaughton DM, Bhai P, Isenring P, Mahdi M, Sadikovic BSchenkel LC. Genotypic analysis of a large cohort of patients with suspected atypical hemolytic uremic syndrome. J Mol Med (Berl). 2023 Aug;101(8):1029-1040. doi: 10.1007/s00109-023-02341-4. Epub 2023 Jul 19. PMID: 37466676 
    39. Dammak S, Cecchini MJ, Breadner D, Ward AD. Using deep learning to predict tumor mutational burden from scans of H&E-stained multicenter slides of lung squamous cell carcinoma. J Med Imaging (Bellingham). 2023 Jan;10(1):017502. doi: 10.1117/1.JMI.10.1.017502. Epub 2023 Feb 21. PMID: 36825084
    40. Darling MR, Hwang JTK, Dickson BJ, Cutz JC, Salama S, McCord C, Pritzker KPH, Mock D, Thompson LDR. Assessing Oral Epithelial Dysplasia Risk for Transformation to Cancer: Comparison Between Histologic Grading Systems Versus S100A7 Immunohistochemical Signature-based Grading. Appl Immunohistochem Mol Morphol. 2023 Jul 1;31(6):399-405. doi: 10.1097/PAI.0000000000001132. Epub 2023 May 23. PMID: 37249075
    41. Dhanuthai K, Chantarangsu S, Klanrit P, Chamusri N, Aminishakib P, Khoozestani NK, Morozan A, Tang C, Singh R, Darling M. Cysts of the jaws: A multicentre study. Oral Dis. 2023 Aug 29. doi: 10.1111/odi.14722. PMID: 37642034
    42. Dinoto A, Zara P, Mariotto S, Ferrari S, Flanagan EP, Budhram A, Orellana D, Turilli D, Solla P, Day GS, Sechi E, Lopez-Chiriboga AS. Autoimmune encephalitis misdiagnosis and mimics. J Neuroimmunol. 2023 Mar 16;378:578071. doi: 10.1016/j.jneuroim.2023.578071. PMID: 36989703
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    109. Routy B, Lenehan JG, Miller WH Jr, Jamal R, Messaoudene M, Daisley BA, Hes C, Al KF, Martinez-Gili L, Punčochář M, Ernst S, Logan D, Belanger K, Esfahani K, Richard C, Ninkov M, Piccinno G, Armanini F, Pinto F, Krishnamoorthy M, Figueredo R, Thebault P, Takis P, Magrill J, Ramsay L, Derosa L, Marchesi JR, Parvathy SN, Elkrief A, Watson IR, Lapointe R, Segata N, Mansour Haeryfar SM, Mullish BH, Silverman MS, Burton JP, Maleki Vareki S. Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial. Nat Med. 2023 Jul 6. doi: 10.1038/s41591-023-02453-x. PMID: 37414899
    110. Routy B, Lenehan JG, Miller WH Jr, Jamal R, Messaoudene M, Daisley BA, Hes C, Al KF, Martinez-Gili L, Punčochář M, Ernst S, Logan D, Belanger K, Esfahani K, Richard C, Ninkov M, Piccinno G, Armanini F, Pinto F, Krishnamoorthy M, Figueredo R, Thebault P, Takis P, Magrill J, Ramsay L, Derosa L, Marchesi JR, Parvathy SN, Elkrief A, Watson IR, Lapointe R, Segata N, Haeryfar SMM, Mullish BH, Silverman MS, Burton JP, Maleki Vareki S. Author Correction: Fecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial. Nat Med. 2023 Nov 3. doi: 10.1038/s41591-023-02650-8. PMID: 37923839 
    111. Saleh AH, Rothe M, Barber DL, McKillop WM, Fraser G, Morel CF, Schambach A, Auray-Blais C, West ML, Khan A, Fowler DH, Rupar CA, Foley R, Medin JA, Keating A. Persistent hematopoietic polyclonality after lentivirus-mediated gene therapy for Fabry disease. Mol Ther Methods Clin Dev. 2023 Jan 18;28:262-271. doi: 10.1016/j.omtm.2023.01.003. eCollection 2023 Mar 9. PMID: 36816757 
    112. Salnikov M, Prusinkiewicz MA, Lin S, Ghasemi F, Cecchini MJ, Mymryk JS.Viruses. Tumor-Infiltrating T Cells in EBV-Associated Gastric Carcinomas Exhibit High Levels of Multiple Markers of Activation, Effector Gene Expression, and Exhaustion. 2023 Jan 7;15(1):176. doi: 10.3390/v15010176. PMID: 36680216
    113. Salnikov MY, Wang E, Christensen E, Prusinkiewicz MA, Shooshtari P, Mymryk JS. The EBV Gastric Cancer Resource (EBV-GCR): A Suite of Tools for Investigating EBV-Associated Human Gastric Carcinogenesis. Viruses. 2023 Mar 27;15(4):853. doi: 10.3390/v15040853. PMID: 37112833 
    114. Sandoval V, Friesen N, Huynh M, Gomez-Lemus JA, Power N. Botryoid-type of embryonal rhabdomyosarcoma of the proximal and mid ureter in an adult woman. Urol Case Rep. 2023 Mar 20;48:102388. doi: 10.1016/j.eucr.2023.102388. eCollection 2023 May. PMID: 37009234 
    115. Santiago-Gómez A, Barkan D, Chambers AF. Editorial: Revisiting seed and soil: A new approach to target hibernating dormant tumor cells. Front Oncol. 2023 Jan 30; 13:1126924. doi: 10.3389/fonc.2023.1126924. eCollection 2023. PMID: 36798827
    116. Sawaya R, Ricard G, McKeon A, Budhram A. Paraneoplastic neuronal intermediate filament autoimmunity with hepatocellular carcinoma. Can J Neurol Sci. 2023 Jul 27:1-5. doi: 10.1017/cjn.2023.264. PMID: 37496428
    117. Schenkel LCMeybodi AM, Selvarajah S. Editorial: Implementation of genomic and epigenomic innovation in clinical cancer diagnostics. Front Oncol. 2023 Aug 10;13:1253630. doi: 10.3389/fonc.2023.1253630. eCollection 2023.PMID: 37637059 
    118. Schonberger ZG, Huang SJY, Thakkar RN, Mamone AA, Khan DI, Chow NLY, Ahmed M, Sivaram N, Bao Y, Kesavan V, Côté J, Sun C, Chhina J, Halvorson BD, Alimorad GH, Menon NJ, Goldman D, Frisbee SJ. Assessments of Perfusion, Blood Flow, and Vascular Structure in Ambulatory Subjects: Guidance for Translational Research Scientists. J Vasc Res. 2023;60(1):12-68. doi: 10.1159/000527765. Epub 2023 Feb 24. PMID: 36843014 
    119. Shaikh MH, Dawson A, Prokopec SD, Barrett JW, Y F Zeng P, Khan MI, Ryan SEB, Cecchini M, Palma DA, Mymryk JS, Boutros PC, Nichols AC. Loss of LRP1B expression drives acquired chemo and radio-resistance in HPV-positive head and neck cancer. Oral Oncol. 2023 Nov;146:106580. doi: 10.1016/j.oraloncology.2023.106580. Epub 2023 Sep 30. PMID: 37778229
    120. Shaw JLV, Arnoldo S, Beach L, Bouhtiauy I, Brinc D, Brun M, Collier C, Kostantin E, Fung AWS, Füzéry AK, Huang Y, Kaur S, Knauer M, Labrecque L, Leung F, Shea JL, Thakur V, Thorlacius L, Venner AA, Yip PM, De Guire V. Establishing quality indicators for point of care glucose testing: recommendations from the Canadian Society for Clinical Chemists Point of Care Testing and Quality Indicators Special Interest Groups. Clin Chem Lab Med. 2023 Apr 12. doi: 10.1515/cclm-2023-0147. PMID: 37043622
    121. Shin AE, Tesfagiorgis Y, Larsen F, Derouet M, Zeng PYF, Good HJ, Zhang L, Kerfoot SM, Nichols AC, Hayakawa Y, Howlett CJ, Wang TC, Asfaha S. F4/80+Ly6Chigh Macrophages Lead to Cell Plasticity and Cancer Initiation in Colitis. Gastroenterology. 2023 Jan 10:S0016-5085(23)00011-2. doi: 10.1053/j.gastro.2023.01.002. PMID: 36634827
    122. Singh SS, Zhong S, Rogers KA, Hachinski VC, Frisbee SJ. Prevalence of dementia, heart disease and stroke in community-dwelling adults in Canada, 2016-2021: opportunities for joint prevention. Arch Public Health. 2023 Aug 24;81(1):158. doi: 10.1186/s13690-023-01171-7. PMID: 37620877
    123. Singh S, Zhong S, Rogers K, Hachinski V, Frisbee S. Prioritizing determinants of cognitive function in healthy middle-aged and older adults: insights from a machine learning regression approach in the Canadian longitudinal study on aging. Front Public Health. 2023 Dec 22;11:1290064. doi: 10.3389/fpubh.2023.1290064. eCollection 2023. PMID: 38186704
    124. Shirley BC, Mucaki EJ, Knoll JHM, Rogan PK. Radiation exposure determination in a secure, cloud-based online environment. Radiat Prot Dosimetry. 2023 Sep 18;199(14):1465-1471. doi: 10.1093/rpd/ncac266. PMID: 37721084
    125. Shooshtari P, Feng S, Nelakuditi V, Asakereh R, Hosseini Naghavi N, Foong J, Brudno M, Cotsapas C. Developing OCHROdb, a comprehensive quality checked database of open chromatin regions from sequencing data. Sci Rep. 2023 May 18;13(1):8106. doi: 10.1038/s41598-022-26791-x. PMID: 37202401
    126. Shukla D, Dinunzio M, Colaiacovo S, Meybodi AM, Saleh M. An uninformative NIPT as an early indicator of cri-du-chat due to a chromosomal 5;18 translocation-An atypical presentation of a rare cytogenetic phenomenon. Clin Case Rep. 2023 Jul 30;11(8):e7732. doi: 10.1002/ccr3.7732. eCollection 2023 Aug. PMID: 37529133 
    127. Sidor NA, Velenosi TJ, Lajoie GA, Filler G, House AA, Weir MA, Thomson BK, Garg AX, Renaud JB, McDowell T, Knauer MJ, Tirona RG, Noble R, Selby N, Taal M, Urquhart BL. Investigation of N,N,N-Trimethyl-L-alanyl-L-proline Betaine (TMAP) as a Biomarker of Kidney Function. ACS Omega. 2023 Apr 21;8(17):15160-15167. doi: 10.1021/acsomega.3c00153. eCollection 2023 May 2. PMID: 37151562 
    128. Singh SS, Stranges S, Wilk P, Tang ASL, Frisbee SJ. Influence of the Social Environment on Ideal Cardiovascular Health. J Am Heart Assoc. 2023 Feb 21;12(4):e026790. doi: 10.1161/JAHA.122.026790. Epub 2023 Feb 15. PMID: 36789849 
    129. Slama L, Hardy WD, Quiñones-Mateu ME, Kuritzkes DR. Alternative options for treatment-experienced people with HIV. AIDS. 2023 Jun 1;37(7):1165-1166. doi: 10.1097/QAD.0000000000003550. PMID: 37139652 
    130. Sooshtari P, Feng B, Biswas S, Levy M, Lin H, Su Z, Chakrabarti S. ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathy. PLoS One. 2022 Aug 19;17(8):e0270287. doi: 10.1371/journal.pone.0270287. eCollection 2022. PMID: 35984863 
    131. Stevic I, Bolsover J, Moore R, Bhayana V. Long term stability of lactate in uncentrifuged sodium fluoride/potassium oxalate blood collection tubes. Ann Clin Biochem. 2023 Nov 10:45632231213746. doi: 10.1177/00045632231213746. PMID: 37903217
    132. Taboun Z, Zeng P, Deluce J, Fung K, Barrett J, Elkadri L, Palma D, Stewart P, Cecchini MJ, Nichols A, Winquist E. Clinical Presentation and Genomic Analysis of HPV-Related Squamous Cell Carcinoma of the Larynx in Two Young Female Patients. Cureus. 2023 Nov 5;15(11):e48316. doi: 10.7759/cureus.48316. eCollection 2023 Nov. PMID: 38058352 
    133. Teplitsky JE, Vinokurtseva A, Armstrong JJ, Denstedt J, Liu H, Hutnik CML. ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts. Transl Vis Sci Technol. 2023 Feb 1;12(2):31. doi: 10.1167/tvst.12.2.31. PMID: 36826843
    134. Thambinathan V, Kinsella EA, Wylie L. Decolonizing trauma studies: A critically reflexive examination of epistemic trauma and intergenerational memory, and its implications for conflict-fleeing migrant diaspora communities. 2023. SSM - Mental Health, 3, art. no. 100225. DOI: 10.1016/j.ssmmh.2023.100225
    135. Tran C, Cipriano LE, Driman DK. Impact of COVID-19-related health care disruptions on pathologic cancer staging during the first pandemic year: a retrospective cohort study from March 2018 to March 2021. CMAJ Open. 2023 Jun 6;11(3):E475-E484. doi: 10.9778/cmajo.20220092. Print 2023 May-Jun. PMID: 37279981
    136. Thang T, Johnson L, Payne RG, Shimizu M, McCord C. Mandibular Involvement Associated With Segmental Odontomaxillary Dysplasia: A Case Series. J Dent Child (Chic). 2023 Nov 15;90(3):168-172. PMID: 38123928
    137. Tunio S, Dzioba A, Dhami R, Elsayed S, Strychowsky JE. Auto-Substitutions to Optimize Perioperative Antimicrobial Prophylaxis: Pre-Post Intervention Study. Laryngoscope. 2023 May 9. doi: 10.1002/lary.30740. PMID: 37159098
    138. Valencia-Sanchez C, Guo Y, Krecke KN, Chen JJ, Redenbaugh V, Montalvo M, Elsbernd PM, Tillema JM, Lopez-Chiriboga S, Budhram A, Sechi E, Kunchok A, Dubey D, Pittock SJ, Lucchinetti CF, Flanagan EP. Cerebral Cortical Encephalitis in Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. Ann Neurol. 2023 Feb;93(2):297-302. doi: 10.1002/ana.26549. Epub 2022 Dec 2. PMID: 36372941
    139. van der Laan L, Rooney K, Haghshenas S, Silva A, McConkey H, Relator R, Levy MA, Valenzuela I, Trujillano L, Lasa-Aranzasti A, Campos B, Castells N, Verberne EA, Maas S, Alders M, Mannens MMAM, van Haelst MM, Sadikovic B, Henneman P. Functional Insight into and Refinement of the Genomic Boundaries of the JARID2-Neurodevelopmental Disorder Episignature. Int J Mol Sci. 2023 Sep 18;24(18):14240. doi: 10.3390/ijms241814240. PMID: 37762546 
    140. van der Laan L, Karimi K, Rooney K, Lauffer P, McConkey H, Caro P, Relator R, Levy MA, Bhai P, Mignot C, Keren B, Briuglia S, Sobering AK, Li D, Vissers LELM, Dingemans AJM, Valenzuela I, Verberne EA, Misra-Isrie M, Zwijnenburg PJG, Waisfisz Q, Alders M, Sailer S, Schaaf CP, Mannens MMAM, Sadikovic B, van Haelst MM, Henneman P. DNA methylation episignature, extension of the clinical features and comparative epigenomic profiling of Hao-Fountain syndrome caused by variants in USP7. Genet Med. 2023 Dec 18:101050. doi: 10.1016/j.gim.2023.101050. PMID: 38126281 
    141. Vijeyakumaran M, Jawhri MA, Fortunato J, Solomon L, Shrestha Palikhe N, Vliagoftis H, Cameron L. Dual activation of estrogen receptor alpha and glucocorticoid receptor upregulate CRTh2-mediated type 2 inflammation; mechanism driving asthma severity in women? Allergy. 2023 Mar;78(3):767-779. doi: 10.1111/all.15543. Epub 2022 Oct 19. PMID: 36207765
    142. Vos N, Reilly J, Elting MW, Campeau PM, Coman D, Stark Z, Tan TY, Amor DJ, Kaur S, StJohn M, Morgan AT, Kamien BA, Patel C, Tedder ML, Merla G, Prontera P, Castori M, Muru K, Collins F, Christodoulou J, Smith J, Zeev BB, Murgia A, Leonardi E, Esber N, Martinez-Monseny A, Casas-Alba D, Wallis M, Mannens M, Levy MA, Relator R, Alders M, Sadikovic B. DNA methylation episignatures are sensitive and specific biomarkers for detection of patients with KAT6A/KAT6B variants. Epigenomics. 2023 Mar;15(6):351-367. doi: 10.2217/epi-2023-0079. Epub 2023 May 30. PMID: 37249002
    143. Wang E, Wang H, Chakrabarti S. Endothelial-to-mesenchymal transition: An underappreciated mediator of diabetic complications. Front Endocrinol (Lausanne). 2023 Jan 27;14:1050540. doi: 10.3389/fendo.2023.1050540. eCollection 2023. PMID: 36777351
    144. Wang E, Feng BChakrabarti S. MicroRNA 9 Is a Regulator of Endothelial to Mesenchymal Transition in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2023 Jun 1;64(7):13. doi: 10.1167/iovs.64.7.13. PMID: 37279396
    145. Wang E, Chen S, Wang H, Chen T, Chakrabarti S. Non-coding RNA-mediated endothelial-to-mesenchymal transition in human diabetic cardiomyopathy, potential regulation by DNA methylation. Cardiovasc Diabetol. 2023 Nov 3;22(1):303. doi: 10.1186/s12933-023-02039-4. PMID: 37924123 
    146. Wang J, Foroutan A, Richardson E, Skinner SA, Reilly J, Kerkhof J, Curry CJ, Tarpey PS, Robertson SP, Maystadt I, Keren B, Dixon JW, Skinner C, Stapleton R, Ruaud L, Gumus E, Lakeman P, Alders M, Tedder ML, Schwartz CE, Friez MJ, Sadikovic B, Stevenson RE. Correction: Clinical findings and a DNA methylation signature in kindreds with alterations in ZNF711. Eur J Hum Genet. 2023 Dec 1. doi: 10.1038/s41431-023-01499-2. PMID: 38040915 
    147. Wang J, Foroutan A, Richardson E, Skinner SA, Reilly J, Kerkhof J, Curry CJ, Tarpey PS, Robertson SP, Maystadt I, Keren B, Dixon JW, Skinner C, Stapleton R, Ruaud L, Gumus E, Lakeman P, Alders M, Tedder ML, Schwartz CE, Friez MJ, Sadikovic B, Stevenson RE. Correction: Clinical findings and a DNA methylation signature in kindreds with alterations in ZNF711. Eur J Hum Genet. 2023 Dec 1. doi: 10.1038/s41431-023-01499-2. PMID: 38040915 
    148. Wang R, Lu KP, Zhou XZ. Function and regulation of cis P-tau in the pathogenesis and treatment of conventional and nonconventional tauopathies. J Neurochem. 2023 Aug 28. doi: 10.1111/jnc.15909. PMID: 37638382 
    149. Wang WC, Preti B, Read N, Gibson P, Kwan K, Winquist E. Case Report: Prolonged remission of metastatic cisplatin-refractory nasopharyngeal carcinoma with Pembrolizumab. Front Oncol. 2023 Nov 8;13:1249453. doi: 10.3389/fonc.2023.1249453. eCollection 2023. PMID: 38023144 
    150. Win PW, Singh SM, Castellani CA. Mitochondrial DNA Copy Number and Heteroplasmy in Monozygotic Twins Discordant for Schizophrenia. Twin Res Hum Genet. 2023 Sep 1:1-10. doi: 10.1017/thg.2023.34. PMID: 37655526
    151. Zara P, Dinoto A, Carta S, Floris V, Turilli D, Budhram A, Ferrari S, Milia S, Solla P, Mariotto S, Flanagan EP, Lopez Chiriboga AS, Sechi E. Non-demyelinating disorders mimicking and misdiagnosed as NMOSD: a literature review. Eur J Neurol. 2023 Jul 11. doi: 10.1111/ene.15983. PMID: 37433584 
    152. Zhang Q, Suller-Marti A, Ding JJ, Deng G, He W, Burneo JG, Hammond RR, Ang LC. Epilepsy-associated death in the Southwestern Ontario: A clinicopathological correlation study. Brain Pathol. 2023 Mar;33(2):e13121. doi: 10.1111/bpa.13121. Epub 2022 Sep 30. PMID: 36180818 
    153. Zhao L, Cheng T, Khalil M. Upper gastrointestinal bleed as the initial presentation of seminoma involving the duodenum in an elderly patient with 9 year follow up: A case report and literature review. Diagn Cytopathol. 2023 Mar 2. doi: 10.1002/dc.25119. PMID: 36861299
    154. Zheng H, Peng A, Peng T. Leashing ferroptosis in myocardial ischemia/reperfusion injury: role of the YAP/NEDD4L/ACSL4 pathway, knowledge gaps and potential therapeutic application. Can J Cardiol. 2023 Aug 31:S0828-282X(23)01644-6. doi: 10.1016/j.cjca.2023.08.025. PMID: 37659755 
    155. Zyla AA, Jacques R. Fatal Rapunzel Syndrome: Gastric and Intestinal Trichobezoars in a Child With Trichotillomania. Am J Forensic Med Pathol. 2023 Jun 6. doi: 10.1097/PAF.0000000000000849. PMID: 37278374

2022 Publications

    1. Afraz S, Stevic I, Matino D, Wen J, Atkinson H, Chan AKC, Hortelano G. Co-administration of FVIII with IVIG reduces immune response to FVIII in hemophilia A mice. Sci Rep. 2022 Nov 22;12(1):20074. doi: 10.1038/s41598-022-19392-1. PMID: 36418333 
    2. Aghamajidi A, Maleki Vareki S. The Effect of the Gut Microbiota on Systemic and Anti-Tumor Immunity and Response to Systemic Therapy against Cancer. Cancers (Basel). 2022 Jul 22;14(15):3563. doi: 10.3390/cancers14153563. PMID: 35892821
    3. Akyeampong E, Bend JR, Luginaah I, Oscar Yawson D, Jerry Cobbina S, Ato Armah F, Osei Adu M, Kofi Essumang D, Iddi S, Botwe PK, Quansah R. Urinary Pesticide Residual Levels and Acute Respiratory Infections in Children Under 5 Years of Age: Findings From the Offinso North Farm Health Study. Environ Health Insights. 2022 Apr 30;16:11786302221094418. doi: 10.1177/11786302221094418. eCollection 2022. PMID: 35521362
    4. Alfano R, Bauman GS, Gomez JA, Gaed M, Moussa M, Chin J, Pautler S, Ward AD. Prostate cancer classification using radiomics and machine learning on mp-MRI validated using co-registered histology. Eur J Radiol. 2022 Aug 19;156:110494. doi: 10.1016/j.ejrad.2022.110494. PMID: 36095953
    5. Alfano R, Bauman GS, Thiessen J, Rachinsky I, Pavlosky W, Butler J, Gaed M, Moussa MGomez JA, Chin JL, Pautler S, Ward AD. Evaluating texture-based prostate cancer classification on multi-parametric magnetic resonance imaging and prostate specific membrane antigen positron emission tomography. SPIE Digital Library, March 16, 2022. doi: 10.1117/12.2551077
    6. Al-Hamad A, Forchuck C, Oudshoorn A, McKinley GP. Listening to the Voices of Syrian Refugee Women in Canada: An Ethnographic Insight into the Journey from Trauma to Adaptation. Journal of International Migration and Integration. 2022. Doi.org/10.1007/s12134-022-00991-w
    7. Al-Jawahiri R, Foroutan A, Kerkhof J, McConkey H, Levy M, Haghshenas S, Rooney K, Turner J, Shears D, Holder M, Lefroy H, Castle B, Reis LM, Semina EV, Lachlan K, Chandler K, Wright T, Clayton-Smith J, Hug FP, Pitteloud N, Bartoloni L, Hoffjan S, Park SM, Thankamony A, Lees M, Wakeling E, Naik S, Hanker B, Girisha KM, Agolini E, Giuseppe Z, Alban Z, Tessarech M, Keren B, Afenjar A, Zweier C, Reis A, Smol T, Tsurusaki Y, Nobuhiko O, Sekiguchi F, Tsuchida N, Matsumoto N, Kou I, Yonezawa Y, Ikegawa S, Callewaert B, Freeth M, Kleinendorst L, Donaldson A, Alders M, De Paepe A, Sadikovic B, McNeill A; University of Washington Center for Mendelian Genomics (UW-CMG); Genomics England Research Consortium. SOX11 variants cause a neurodevelopmental disorder with infrequent ocular malformations and hypogonadotropic hypogonadism and with distinct DNA methylation profile. Genet Med. 2022 Mar 24:S1098-3600(22)00665-7. doi: 10.1016/j.gim.2022.02.013. PMID: 35341651
    8. Alkabie S, Budhram A. Testing for Antibodies Against Aquaporin-4 and Myelin Oligodendrocyte Glycoprotein in the Diagnosis of Patients With Suspected Autoimmune Myelopathy. Front Neurol. 2022 May 20;13:912050. doi: 10.3389/fneur.2022.912050. eCollection 2022. PMID: 35669883
    9. Alkabie S, Chang YC, Budhram A, Racosta JM. Pearls & Oy-sters: Gait Instability, Jaw Dystonia, and Horizontal Diplopia in a Woman With Anti-Ri Antibodies and Breast Cancer. Neurology. 2022 Apr 29:10.1212/WNL.0000000000200712. doi: 10.1212/WNL.0000000000200712. PMID: 35487696
    10. Alturkustani M, Ang LC. White matter cellular changes in ischemic injuries. Am J Transl Res. 2022 Aug 15;14(8):5859-5869. eCollection 2022. PMID: 36105017 
    11. Amos K, Garcia-Bournissen F, Zhao L, Taheri S. Carbamazepine-induced liver injury in an 11-year-old female: Case report and review of the literature. J Paediatr Child Health. 2022 Sep 7. doi: 10.1111/jpc.16200. Online ahead of print. PMID: 36069405 
    12. Arboleda B, Bartsch R, de Azambuja E, Hamilton E, Harbeck N, Klemp J, Knauer M, Kuemmel S, Mahtani R, Schwartzberg L, Villarreal-Garza C, Wolff A. Ovarian Function Suppression: A Deeper Consideration of the Role in Early Breast Cancer and its Potential Impact on Patient Outcomes: A Consensus Statement from an International Expert Panel. Oncologist. 2022 Jun 15:oyac101. doi: 10.1093/oncolo/oyac101. Online ahead of print. PMID: 35704278 
    13. Asadi F, Dhanvantari S. Misrouting of glucagon and stathmin-2 towards lysosomal system of α-cells in glucagon hypersecretion of diabetes. Islets. 2022 Dec 31;14(1):40-57. doi: 10.1080/19382014.2021.2011550. PMID: 34923907
    14. Asadi F, Fernandez Andrade JA, Gillies R, Lee K, Dhanvantari S, Hardy DB, Arany EJ. Sex-dependent Effect of In-utero Exposure to Δ9-Tetrahydrocannabinol on Glucagon and Stathmin-2 in Adult Rat Offspring. Can J Diabetes. 2022 Jul 5:S1499-2671(22)00178-2. doi: 10.1016/j.jcjd.2022.06.009. PMID: 35985923
    15. Asif Z, Chen Z, Stranges S, Zhao X, Sadiq R, Olea-Popelka F, Peng C, Haghighat F, Yu T. Dynamics of SARS-CoV-2 spreading under the influence of environmental factors and strategies to tackle the pandemic: A systematic review. Sustain Cities Soc. 2022 Jun;81:103840. doi: 10.1016/j.scs.2022.103840. Epub 2022 Mar 16. PMID: 35317188
    16. Aziz SJ, Zeman-Pocrnich CE. Tissue Processing. Methods Mol Biol. 2022;2422:47-63. doi: 10.1007/978-1-0716-1948-3_4. PMID: 34859398
    17. Badiuk SR, Thiessen JD, Maleki Vareki S, Foster PJ, Chen JZ, Wong E. Glial activation positron emission tomography imaging in radiation treatment of breast cancer brain metastases. Phys Imaging Radiat Oncol. 2022 Mar 1;21:115-122. doi: 10.1016/j.phro.2022.02.016. eCollection 2022 Jan. PMID: 35359488
    18. Barkan D, Chambers AF, Gómez AS, eds. (2022).  Revisiting Seed and Soil: A New Approach to Target Hibernating Dormant Tumor Cells.  Lausanne: Frontiers Media SA. doi: 10.3389/978-2-88976-342-9.  https://www.frontiersin.org/research-topics/11147/revisiting-seed-and-soil-a-new-approach-to-target-hibernating-dormant-tumor-cells
    19. Bell KA, Kim R, Aronson M, Gillies B, Ali Awan A, Chun K, Hart J, Healey R, Kim L, Klaric G, Panabaker K, Sabatini PJB, Sadikovic B, Selvarajah S, Smith AC, Stockley TL, Vaags AK, Eisen A, Pollett A, Feilotter H. Development of a comprehensive approach to adult hereditary cancer testing in Ontario. J Med Genet. 2022 Dec 23:jmg-2022-108945. doi: 10.1136/jmg-2022-108945. PMID: 36564171
    20. Bhai P, Hsia CC, Schenkel LC, Hedley BD, Levy MA, Kerkhof J, Santos S, Stuart A, Lin H, Broadbent R, Nan S, Yang P, Xenocostas A, Chin-Yee ISadikovic B. Clinical Utility of Implementing a Frontline NGS-Based DNA and RNA Fusion Panel Test for Patients with Suspected Myeloid Malignancies. Mol Diagn Ther. 2022 Apr 5. doi: 10.1007/s40291-022-00581-7. PMID: 35381971
    21. Bhai P, Chin-Yee B, Pope V, Cheong I, Matyashin M, Levy MA, Foroutan A, Stuart A, Hsia CC, Lin H, Sadikovic B, Chin-Yee I. Mutational Landscape of Patients Referred for Elevated Hemoglobin Level. Curr Oncol. 2022 Sep 30;29(10):7209-7217. doi: 10.3390/curroncol29100568. PMID: 36290845
    22. Biswas S, Coyle A, Chen S, Gostimir M, Gonder J, Chakrabarti S. Expressions of Serum lncRNAs in Diabetic Retinopathy - A Potential Diagnostic Tool. Front Endocrinol (Lausanne). 2022 Apr 7;13:851967. doi: 10.3389/fendo.2022.851967. PMID: 35464068
    23. Biswas A, Wehrli B, McGuire T, Darling M. A painless swelling of the left face. Oral Surg Oral Med Oral Pathol Oral Radiol. 2022 Apr 10:S2212-4403(22)00896-3. doi: 10.1016/j.oooo.2022.04.001. PMID: 35599212 
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    162. Spurgeon ME, Cheng J, Ward-Shaw E, Dick FA, DeCaprio JA, Lambert PF. Merkel cell polyomavirus large T antigen binding to pRb promotes skin hyperplasia and tumor development. PLoS Pathog. 2022 May 13;18(5):e1010551. doi: 10.1371/journal.ppat.1010551. eCollection 2022 May. PMID: 35560034
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    164. Szeto VG, Chin-Yee B, Dehghani M, Rizkalla K, Licskai C, Hsia CC. Successful treatment of Kimura disease with benralizumab. Ann Hematol. 2022 May 27. doi: 10.1007/s00277-022-04873-0. PMID: 35622096
    165. Thomas Q, Motta M, Gautier T, Zaki MS, Ciolfi A, Paccaud J, Girodon F, Boespflug-Tanguy O, Besnard T, Kerkhof J, McConkey H, Masson A, Denommé-Pichon AS, Cogné B, Trochu E, Vignard V, El It F, Rodan LH, Alkhateeb MA, Jamra RA, Duplomb L, Tisserant E, Duffourd Y, Bruel AL, Jackson A, Banka S, McEntagart M, Saggar A, Gleeson JG, Sievert D, Bae H, Lee BH, Kwon K, Seo GH, Lee H, Saeed A, Anjum N, Cheema H, Alawbathani S, Khan I, Pinto-Basto J, Teoh J, Wong J, Sahari UBM, Houlden H, Zhelcheska K, Pannetier M, Awad MA, Lesieur-Sebellin M, Barcia G, Amiel J, Delanne J, Philippe C, Faivre L, Odent S, Bertoli-Avella A, Thauvin C, Sadikovic B, Reversade B, Maroofian R, Govin J, Tartaglia M, Vitobello A. Bi-allelic loss-of-function variants in TMEM147 cause moderate to profound intellectual disability with facial dysmorphism and pseudo-Pelger-Huët anomaly. Am J Hum Genet. 2022 Aug 23:S0002-9297(22)00360-3. doi: 10.1016/j.ajhg.2022.08.008. PMID: 36044892 
    166. van der Laan L, Rooney K, Alders M, Relator R, McConkey H, Kerkhof J, Levy MA, Lauffer P, Aerden M, Theunis M, Legius E, Tedder ML, Vissers LELM, Koene S, Ruivenkamp C, Hoffer MJV, Wieczorek D, Bramswig NC, Herget T, González VL, Santos-Simarro F, Tørring PM, Denomme-Pichon AS, Isidor B, Keren B, Julia S, Schaefer E, Francannet C, Maillard PY, Misra-Isrie M, Van Esch H, Mannens MMAM, Sadikovic B, van Haelst MM, Henneman P. Episignature Mapping of TRIP12 Provides Functional Insight into Clark-Baraitser Syndrome. Int J Mol Sci. 2022 Nov 8;23(22):13664. doi: 10.3390/ijms232213664. PMID: 36430143 
    167. van Jaarsveld RH, Reilly J, Cornips MC, Hadders MA, Agolini E, Ahimaz P, Anyane-Yeboa K, Bellanger SA, van Binsbergen E, van den Boogaard MJ, Brischoux-Boucher E, Caylor RC, Ciolfi A, van Essen TAJ, Fontana P, Hopman S, Iascone M, Javier MM, Kamsteeg EJ, Kerkhof J, Kido J, Kim HG, Kleefstra T, Lonardo F, Lai A, Lev D, Levy MA, Lewis MES, Lichty A, Mannens MMAM, Matsumoto N, Maya I, McConkey H, Megarbane A, Michaud V, Miele E, Niceta M, Novelli A, Onesimo R, Pfundt R, Popp B, Prijoles E, Relator R, Redon S, Rots D, Rouault K, Saida K, Schieving J, Tartaglia M, Tenconi R, Uguen K, Verbeek N, Walsh CA, Yosovich K, Yuskaitis CJ, Zampino G, Sadikovic B, Alders M, Oegema R. Delineation of a KDM2B-related neurodevelopmental disorder and its associated DNA methylation signature. Genet Med. 2022 Nov 1:S1098-3600(22)00942-X. doi: 10.1016/j.gim.2022.09.006. PMID: 36322151 
    168. Verberne EA, van der Laan L, Haghshenas S, Rooney K, Levy MA, Alders M, Maas SM, Jansen S, Lieden A, Anderlid BM, Rafael-Croes L, Campeau PM, Chaudhry A, Koolen DA, Pfundt R, Hurst ACE, Tran-Mau-Them F, Bruel AL, Lambert L, Isidor B, Mannens MMAM, Sadikovic B, Henneman P, van Haelst MM. DNA Methylation Signature for JARID2-Neurodevelopmental Syndrome. Int J Mol Sci. 2022 Jul 20;23(14):8001. doi: 10.3390/ijms23148001. PMID: 35887345  
    169. Vermij L, Léon-Castillo A, Singh N, Powell ME, Edmondson RJ, Genestie C, Khaw P, Pyman J, McLachlin CM, Ghatage P, de Boer SM, Nijman HW, Smit VTHBM, Crosbie EJ, Leary A, Creutzberg CL, Horeweg N, Bosse T; TransPORTEC consortium. p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial. Mod Pathol. 2022 Jun 25. doi: 10.1038/s41379-022-01102-x. PMID: 35752743
    170. Vijeyakumaran M, Jawhri MA, Fortunato J, Solomon L, Shrestha Palikhe N, Vliagoftis H, Cameron L. Dual activation of estrogen receptor alpha and glucocorticoid receptor upregulate CRTh2-mediated type 2 inflammation; mechanism driving asthma severity in women? Allergy. 2022 Oct 7. doi: 10.1111/all.15543. PMID: 36207765
    171. Vinokurtseva A, Armstrong JJ, Liu H, Hutnik CML. Differential effects of acetylsalicylic acid and mitomycin C on cytokine-induced Tenon's capsule myofibroblast transdifferentiation and activity: Implications for glaucoma surgery. Exp Eye Res. 2022 Oct 21;225:109284. doi: 10.1016/j.exer.2022.109284. PMID: 36273575
    172. von Lubitz DKJE, Gibson CJ. The Nature of Pandemics, Boca Raton, CRC Pres., 1st Edition - November 2, 2022. doi: 10.4324/9781315170220 ISBN: 9781315170220
    173. Wang J, Foroutan A, Richardson E, Skinner SA, Reilly J, Kerkhof J, Curry CJ, Tarpey PS, Robertson SP, Maystadt I, Keren B, Dixon JW, Skinner C, Stapleton R, Ruaud L, Gumus E, Lakeman P, Alders M, Tedder ML, Schwartz CE, Friez MJ, Sadikovic B, Stevenson RE. Clinical findings and a DNA methylation signature in kindreds with alterations in ZNF711.Eur J Hum Genet. 2022 Jan 7. doi: 10.1038/s41431-021-01018-1. PMID: 34992252
    174. Wang P, Castellani CA, Yao J, Huan T, Bielak LF, Zhao W, Haessler J, Joehanes R, Sun X, Guo X, Longchamps RJ, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Van Den Berg DJ, Hou L, Reiner A, Liu Y, Boerwinkle E, Smith JA, Peyser PA, Fornage M, Rich SS, Rotter JI, Kooperberg C, Arking DE, Levy D, Liu C; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Epigenome-wide association study of mitochondrial genome copy number. Hum Mol Genet. 2021 Dec 27;31(2):309-319. doi: 10.1093/hmg/ddab240. PMID: 34415308
    175. Wiebe N, Sangle N, McGee J. Extramedullary plasmacytoma of the uterine cervix arising in an asymptomatic 46-year-old female. Gynecol Oncol Rep. 2022 Oct 13;44:101087. doi: 10.1016/j.gore.2022.101087. eCollection 2022 Dec. PMID: 36277031
    176. Williams S, Stoskopf M, Francis-Floyd R, Koutsos L, Dierenfeld E, Harmon T, Cicotello E, German D, Semmen K, Keaffaber J, Olea-Popelka F, Livingston S, Sullivan K, Valdes E. Recommendations and Action Plans to Improve Ex-situ Nutrition and Health of Marine Teleosts. J Aquat Anim Health. 2022 Feb 24. doi: 10.1002/aah.10150. PMID: 35199884
    177. Wishart T, DeMars D, McKinley GP.  The Self Appreciation Project: An Exploratory Study on Social Media Mental Health Promotion. Journal of Prevention and Health Promotion. 2022, Vol. 28: 200248. Doi.org/10.1016/j.mph.2022.200248 
    178. Wu X, Cheung CKY, Ye D, Chakrabarti S, Mahajan H, Yan S, Song E, Yang W, Lee CH, Lam KSL, Wang C, Xu A. Serum Thrombospondin-2 Levels Are Closely Associated With the Severity of Metabolic Syndrome and Metabolic Associated Fatty Liver Disease. J Clin Endocrinol Metab. 2022 Jul 14;107(8):e3230-e3240. doi: 10.1210/clinem/dgac292. PMID: 35532410
    179. Xu Z, Luo W, Chen L, Zhuang Z, Yang D, Qian J, Khan ZA, Guan X, Wang Y, Li X, Liang G. Ang II (Angiotensin II)-Induced FGFR1 (Fibroblast Growth Factor Receptor 1) Activation in Tubular Epithelial Cells Promotes Hypertensive Kidney Fibrosis and Injury. Hypertension. 2022 Sep;79(9):2028-2041. doi: 10.1161/HYPERTENSIONAHA.122.18657. Epub 2022 Jul 11. PMID: 35862110
    180. Yang JH, Friederich MW, Ellsworth KA, Frederick A, Foreman E, Malicki D, Dimmock D, Lenberg J, Prasad C, Yu AC, Rupar CA, Hegele RA, Manickam K, Koboldt DC, Crist E, Choi SS, Farhan SMK, Harvey H, Sattar S, Karp N, Wong T, Haas R, Van Hove JLK, Wigby K. Expanding the phenotypic and molecular spectrum of NFS1-related disorders that cause functional deficiencies in mitochondrial and cytosolic iron-sulfur cluster containing enzymes. Hum Mutat. 2022 Jan 13. doi: 10.1002/humu.24330. PMID: 35026043
    181. Yang P, Broadbent R, Prasad C, Levin S, Goobie S, Knoll JH, Prasad AN. De novo STXBP1 Mutations in Two Patients With Developmental Delay With or Without Epileptic Seizures. Front Neurol. 2021 Dec 24;12:804078. doi: 10.3389/fneur.2021.804078. eCollection 2021. PMID: 35002943
    182. Yoon JY, Chapel D, Goebel E, Qian X, Mito J, Horowitz N, Miron A, Soong TR, Xian W, Crum CP. Molecular catastrophe, the peritoneal cavity and ovarian cancer prevention. J Pathol. 2022 Mar 2. doi: 10.1002/path.5891. PMID: 35238033 
    183. Yuan M, Bedell S, de Vrijer B, Eastabrook G, Frisbee JC, Frisbee SJ. Highlighting the Mechanistic Relationship Between Perinatal Depression and Preeclampsia: A Scoping Review. Womens Health Rep (New Rochelle). 2022 Oct 26;3(1):850-866. doi: 10.1089/whr.2022.0062. eCollection 2022.PMID: 36340477
    184. Zeng PYF, Cecchini MJ, Barrett JW, Shammas-Toma M, De Cecco L, Serafini MS, Cavalieri S, Licitra L, Hoebers F, Brakenhoff RH, Leemans CR, Scheckenbach K, Poli T, Wang X, Liu X, Laxague F, Prisman E, Poh C, Bose P, Dort JC, Shaikh MH, Ryan SEB, Dawson A, Khan MI, Howlett CJ, Stecho W, Plantinga P, Daniela da Silva S, Hier M, Khan H, MacNeil D, Mendez A, Yoo J, Fung K, Lang P, Winquist E, Palma DA, Ziai H, Amelio AL, Li SS, Boutros PC, Mymryk JS, Nichols AC. Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification. EBioMedicine. 2022 Dec;86:104373. doi: 10.1016/j.ebiom.2022.104373. Epub 2022 Nov 25. PMID: 36442320
    185. Zhang L, Zheng D, Yan Y, Yu Y, Chen R, Li Z, Greer PA, Peng T, Wang Q. Myeloid cell-specific deletion of Capns1 prevents macrophage polarization toward the M1 phenotype and reduces interstitial lung disease in the bleomycin model of systemic sclerosis. Arthritis Res Ther. 2022 Jun 21;24(1):148. doi: 10.1186/s13075-022-02833-7. PMID: 35729674
    186. Zhang M, Zhong H, Cao T, Huang Y, Ji X, Fan GC, Peng T. Gamma-Aminobutyrate Transaminase Protects against Lipid Overload-Triggered Cardiac Injury in Mice. Int J Mol Sci. 2022 Feb 16;23(4):2182. doi: 10.3390/ijms23042182. PMID: 35216295
    187. Zhang Q, Abdo R, Iosef C, Kaneko T, Cecchini M, Han VK, Li SS. The spatial transcriptomic landscape of non-small cell lung cancer brain metastasis. Nat Commun. 2022 Oct 10;13(1):5983. doi: 10.1038/s41467-022-33365-y. PMID: 36216799 
    188. Zhang Q, Suller-Marti A, Ding JJ, Deng G, He W, Burneo JG, Hammond RR, Ang LC. Epilepsy-associated death in the Southwestern Ontario: A clinicopathological correlation study. Brain Pathol. 2022 Sep 30:e13121. doi: 10.1111/bpa.13121. PMID: 36180818
    189. Zhao CS, Yan L, He W, Ang LC, Zhang Q. Distinct subcortical tau burden: The tau pallido-claustral ratio separates progressive supranuclear palsy and corticobasal degeneration. Brain Pathol. 2022 Mar;32(2):e13030. doi: 10.1111/bpa.13030. Epub 2021 Oct 20. PMID: 34672063 
    190. Zhao X, Lu C, Yang S, Ni R, Peng T, Zhang J. Synthesis of N, N, N-trimethyl chitosan-based nanospheres for the prolonged release of curcumin. Food Hydrocolloids for Health, 2 2022. doi: 10.1016/j.fhfh.2022.100092

2021 Publications

    1. Almobarak S, Hu J, Langdon KD, Ang LC, Campbell C. α-tropomyosin gene (TPM3) mutation in an infant with nemaline myopathy. Clin Case Rep. 2021 Feb 3;9(3):1672-1676. doi: 10.1002/ccr3.3866. eCollection 2021 Mar. PMID: 33768912
    2. Almog G, Olabode AS, Poon AFY. Tuning intrinsic disorder predictors for virus proteins. Virus Evol. 2021 Jan 25;7(1):veaa106. doi: 10.1093/ve/veaa106. eCollection 2021 Jan. PMID: 33614158
    3. Amtul Z, Najdat AN, Hill DJ, Arany EJ. Differential temporal and spatial post-injury alterations in cerebral cell morphology and viability. J Comp Neurol. 2021 Feb;529(2):421-433. doi: 10.1002/cne.24955. Epub 2020 Jun 28. PMID: 32447764
    4. Aref-Eshghi E, Kerkhof J, Carere DA, Volodarsky M, Bhai P, Colaiacovo S, Saleh M, Caudle M, Karp N, Prasad C, Balci T, Lin H, Campbell C, Siu VM, Sadikovic B. Clinical and technical assessment of MedExome vs. NGS panels in patients with suspected genetic disorders in Southwestern Ontario. J Hum Genet. 2021 May;66(5):451-464. doi: 10.1038/s10038-020-00860-3. Epub 2020 Oct 23. PMID: 33093641
    5. Armstrong JJ, Zhang R, Fung M, Zeman-Pocrnich C, Rotenberg B, Bauman G, Gilbert K, Hutnik CML. Rapid visual field progression in a patient with glaucoma as the presenting manifestation of sarcoidosis. Am J Ophthalmol Case Rep. 2021 Jun 5;23:101132. doi: 10.1016/j.ajoc.2021.101132. eCollection 2021 Sep. PMID: 34151046
    6. Asadi F, Dhanvantari S. Pathways of Glucagon Secretion and Trafficking in the Pancreatic Alpha Cell: Novel Pathways, Proteins, and Targets for Hyperglucagonemia. Front Endocrinol (Lausanne). 2021 Sep 29;12:726368. doi: 10.3389/fendo.2021.726368. eCollection 2021. PMID: 34659118 
    7. Aziz S, Sey M, Marotta P, Driman D, Parfitt J, Teriaky A, Brahmania M, Skaro A, Qumosani K. Recurrent Hepatocellular Carcinoma After Liver Transplantation: Validation of a Pathologic Risk Score on Explanted Livers to Predict Recurrence. Transplant Proc. 2021 Jul 13:S0041-1345(21)00412-7. doi: 10.1016/j.transproceed.2021.05.007. Online ahead of print. PMID: 34272052
    8. Aziz SJ, Zeman-Pocrnich CE. Tissue Processing. Methods Mol Biol. 2022;2422:47-63. doi: 10.1007/978-1-0716-1948-3_4. PMID: 34859398
    9. Baranova K, Goebel EA, McGee J, Walsh JC. A Case of Synchronous Malignant and Benign Granular Cell Tumor of the Vulva. Int J Gynecol Pathol. 2021 Sep 1;40(5):460-464. doi: 10.1097/PGP.0000000000000712. PMID: 32947331
    10. Baranova K, Goebel EA, Wasserman J, Osmond A. A Survey on Changes to the Canadian Anatomical Pathology Certification Examination Due to Coronavirus Disease 2019 and Implications for Competency-Based Medical Education. Acad Pathol. 2021 Dec 13;8:23742895211060711. doi: 10.1177/23742895211060711. eCollection 2021 Jan-Dec. PMID: 34926797
    11. Bartlett J, Amemiya Y, Arts H, Bayani J, Eng B, Grafodatskaya D, Kamel Reid S, Lariviere M, Lo B, McClure R, Mittal V, Sadikovic B, Sadis S, Seth A, Smith J, Zhang X, Feilotter H. Multisite verification of the accuracy of a multi-gene next generation sequencing panel for detection of mutations and copy number alterations in solid tumours. PLoS One. 2021 Oct 1;16(10):e0258188. doi: 10.1371/journal.pone.0258188. eCollection 2021. PMID: 34597339 
    12. Beach LA, Fung AWS, Knauer MJ, Shaw JLV, Taher J. Rapid COVID-19 testing: Speed, quality and cost. Can you have all three? Clin Biochem. 2021 May 26:S0009-9120(21)00150-8. doi: 10.1016/j.clinbiochem.2021.05.009. Online ahead of print. PMID: 34048775
    13. Bhai P, Levy MA, Rooney K, Carere DA, Reilly J, Kerkhof J, Volodarsky M, Stuart A, Kadour M, Panabaker K, Schenkel LC, Lin H, Ainsworth PSadikovic B. Analysis of Sequence and Copy Number Variants in Canadian Patient Cohort With Familial Cancer Syndromes Using a Unique Next Generation Sequencing Based Approach. Front Genet. 2021 Jul 13;12:698595. doi: 10.3389/fgene.2021.698595. eCollection 2021. PMID: 34326862 
    14. Biswas S, Feng B, Chen S, Liu J, Aref-Eshghi E, Gonder J, Ngo V, Sadikovic B, Chakrabarti S. The Long Non-Coding RNA HOTAIR Is a Critical Epigenetic Mediator of Angiogenesis in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):20. doi: 10.1167/iovs.62.3.20. PMID: 33724292
    15. Borjian Boroujeni P, Beheshti Z, Eshaghi Zadeh SH, Afsharian P, Mohseni Meybodi A.Spontaneous and induced chromosomal aberrations in peripheral blood of women with endometriosis: evidence of genomic instability. Minerva Obstet Gynecol. 2021 Jun;73(3):369-375. doi: 10.23736/S2724-606X.21.04773-4. PMID: 34008392
    16. Brintnell E, Gupta M, Anderson DW. Phylogenetic and Ancestral Sequence Reconstruction of SARS-CoV-2 Reveals Latent Capacity to Bind Human ACE2 Receptor. J Mol Evol. 2021 Dec;89(9-10):656-664. doi: 10.1007/s00239-021-10034-0. Epub 2021 Nov 5. PMID: 34739551
    17. Buss P, Miller M, Fuller A, Haw A, Thulson E, Olea-Popelka F, Meyer L. Effect of Azaperone on Induction Times in Etorphine-Immobilized White Rhinoceros (Ceratotherium simum). J Wildl Dis. 2021 Oct 25. doi: 10.7589/JWD-D-21-00072. PMID: 34695196
    18. Calovini AK, Armstrong CE, Ettler HC, Zeman-Pocrnich CE. A breast sentinel lymph node protocol revisited: A quality improvement initiative. Canadian Journal of Pathology. May 2021, Vol. 13 Issue 2, p26-33. 8p. 
    19. Campos-Melo D, Hawley ZCE, Droppelmann CA, Strong MJ. The Integral Role of RNA in Stress Granule Formation and Function. Front Cell Dev Biol. 2021 May 20;9:621779. doi: 10.3389/fcell.2021.621779. eCollection 2021. PMID: 34095105 
    20. Cheah M, Wilson A, Solh Z, Khanna R. IgA-Mediated Warm Autoimmune Hemolytic Anemia as an Extraintestinal Manifestation in a Patient With Crohn Disease on Vedolizumab. Inflamm Bowel Dis. 2021 May 18:izab090. doi: 10.1093/ibd/izab090. Online ahead of print. PMID: 34003281
    21. Cheng YR, Li X, Zhao X, Lin H. Cell entry of animal coronaviruses. 2021. Viruses, 13(10), art. no. 1977.
    22. Chakraborty D, Shepherd J, Gregor J, Dhaliwal I. The Tricky Trachea: Tracheitis and Mediastinitis Treated With Infliximab and Steroids in a Patient With Ulcerative Colitis. Chest. 2021 Sep;160(3):e255-e258. doi: 10.1016/j.chest.2021.03.060. PMID: 34488963
    23. Chalil A, Cairncross JG, Hawkins C, Leung AE, Hebb M, Hammond RR. Clinical neuropathological conference: There's a child in all of us. 2021. Canadian Journal of Neurological Sciences, 48(6), 869-873. doi:10.1017/cjn.2021.24
    24. Chan IYM, Li H, Shi THammond RR, Jurkiewicz MT. Parietal Convexity Meningeal Melanocytoma: Radiologic-Pathologic Correlation. Can J Neurol Sci. 2021 Sep;48(5):719-721. doi: 10.1017/cjn.2020.256. Epub 2020 Nov 20. PMID: 33213533 
    25. Charyk Stewart T, Edwards J, Penney A, Gilliland J, Clark A, Haidar T, Batey B, Pfeffer A, Fraser DD, Merritt NH, Parry NG. Evaluation of a population health strategy to reduce distracted driving: Examining all "Es" of injury prevention. J Trauma Acute Care Surg. 2021 Mar 1;90(3):535-543. doi: 10.1097/TA.0000000000002948. PMID: 32976325
    26. Chen L, Almudaires A, Alzahrani M, Qumosani K, Chakrabarti S. IgG4-related disease as a rare cause of gastric outlet obstruction: a case report and literature review. BMC Gastroenterol. 2021 Sep 20;21(1):349. doi: 10.1186/s12876-021-01927-x. PMID: 34544364 
    27. Cheng C, Pei X, Li SW, Yang J, Li C, Tang J, Hu K, Huang G, Min WP, Sang Y. RISPR/Cas9 library screening uncovered methylated PKP2 as a critical driver of lung cancer radioresistance by stabilizing β-catenin. Oncogene. 2021 Apr;40(16):2842-2857. doi: 10.1038/s41388-021-01692-x. Epub 2021 Mar 19. PMID: 33742119
    28. Cheng C, Yang J, Li SW, Huang G, Li C, Min WP, Sang Y. HDAC4 promotes nasopharyngeal carcinoma progression and serves as a therapeutic target. Cell Death Dis. 2021 Feb 1;12(2):137. doi: 10.1038/s41419-021-03417-0. PMID: 33542203
    29. Cheng YR, Li X, Zhao X, Lin H. Cell entry of animal coronaviruses. Viruses. 2021 Oct 1;13(10):1977. doi: 10.3390/v13101977 PMID: 34696406
    30. Chung J, Stevic I, Gantioqui J, Atkinson H, Chan AKC, Chan HHW. Effect of unfractionated heparin and low molecular weight heparin on the clotting of platelet-reduced whole blood: an in-vitro study utilizing thromboelastography. Blood Coagul Fibrinolysis. 2021 Jul 1;32(5):305-311. doi: 10.1097/MBC.0000000000001023. PMID: 34231501
    31. Ciolfi A, Foroutan A, Capuano A, Pedace L, Travaglini L, Pizzi S, Andreani M, Miele E, Invernizzi F, Reale C, Panteghini C, Iascone M, Niceta M, Gavrilova RH, Schultz-Rogers L, Agolini E, Bedeschi MF, Prontera P, Garibaldi M, Galosi S, Leuzzi V, Soliveri P, Olson RJ, Zorzi GS, Garavaglia BM, Tartaglia M, Sadikovic B. Childhood-onset dystonia-causing KMT2B variants result in a distinctive genomic hypermethylation profile. Clin Epigenetics. 2021 Aug 11;13(1):157. doi: 10.1186/s13148-021-01145-y. PMID: 34380541
    32. Dear T, Yu YJ, Pandey S, Fuller J, Devlin MK. The first described case of lodderomyces elongisporus meningitis. 2021. JAMMI, 6(3), 221-228. doi:10.3138/JAMMI-2021-0006 
    33. Diaz-Gonzalez de Ferris ME, Díaz-González de Martínez ML, Díaz-González de Velázquez AM, Díaz-González Borja A, Díaz-González Borja A, Filler G, Alvarez-Elías AC, Díaz-González Borja V. An Interdisciplinary Approach to Optimize the Care of Transitioning Adolescents and Young Adults with CKD. Blood Purif. 2021 Mar 11:1-12. doi: 10.1159/000513520. Online ahead of print. PMID: 33706317
    34. Diaz-Gonzalez de Ferris ME, Ferris MT, Filler G. Transition from paediatric to adult-focused care: unresolved issues. Nat Rev Nephrol. 2021 Aug 12. doi: 10.1038/s41581-021-00476-6. Online ahead of print. PMID: 34385678 
    35. Ding JJ, Liu P, Rebernig H, Suller-Marti A, Parrent AG, Burneo JG, Hammond R, Ang LC, Zhang Q. Vagus nerve stimulation does not alter brainstem nuclei morphology in patients with refractory epilepsy. Epilepsy and Behavior, 2021. 118 doi:10.1016/j.yebeh.2021.107940 PMID: 33838622
    36. Esmail S, Knauer MJ, Abdoh H, Voss C, Chin-Yee B, Stogios P, Seitova A, Hutchinson A, Yusifov F, Skarina T, Evdokimova E, Ackloo S, Lowes L, Hedley BD, Bhayana V, Chin-Yee I, Li SS. Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodies. Cell Rep Methods. 2021 Jun 21;1(2):100011. doi: 10.1016/j.crmeth.2021.100011. Epub 2021 May 12. PMID: 34235498
    37. Ferreira RC, Prodger JL, Redd AD, Poon AFY. Quantifying the clonality and dynamics of the within-host HIV-1 latent reservoir. Virus Evol. 2021 Jan 6;7(1):veaa104. doi: 10.1093/ve/veaa104. eCollection 2021 Jan. PMID: 33505711
    38. Filler G, Ferris MED. Discrepant changes of urinary cystatin C and other urinary biomarkers in preterm neonates. J Pediatr (Rio J). 2021 Feb 24:S0021-7557(21)00033-4. doi: 10.1016/j.jped.2021.02.002. Online ahead of print. PMID: 33639089
    39. Filler G, de Ferris MED, Elliott L. Marginal parent donors-Process and ethics. Pediatr Transplant. 2021 Jun 2:e14062. doi: 10.1111/petr.14062. Online ahead of print. PMID: 34076958
    40. Filler G, Geda R, Salerno F, Zhang YC, de Ferris MED, McIntyre CW. Management of severe polyuria in idiopathic Fanconi syndrome. Pediatr Nephrol. 2021 Aug 24. doi: 10.1007/s00467-021-05213-6. Online ahead of print. PMID: 34427794
    41. Fournier DE, Beaucage KL, Beach RJ, Kiser PK, Séguin CA, Dixon SJ. Ectopic mineralisation of the mandibular symphysis in ENT1 knockout mice: A model of dystrophic calcification. Bone Rep. 2021 Jun 18;15:101100. doi: 10.1016/j.bonr.2021.101100. eCollection 2021 Dec. PMID: 34258331 
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    108. Randhawa VK, Dhanvantari S, Connelly KA. How Diabetes and Heart Failure Modulate Each Other and Condition Management. Can J Cardiol. 2021 Apr;37(4):595-608. doi: 10.1016/j.cjca.2020.11.014. Epub 2020 Dec 1. PMID: 33276047
    109. Ray L, Wylie L, Corrado AM. Shapeshifters, systems thinking and settler colonial logic: Expanding the framework of analysis of Indigenous health equity. Soc Sci Med. 2021 Sep 25:114422. doi: 10.1016/j.socscimed.2021.114422. Online ahead of print. PMID: 34625325
    110. Restrepo JM, Torres-Canchala L, Cadavid JCA, Ferguson M, Villegas A, Ramirez O, Rengifo M, Filler G. J Pediatr (Rio J). Renal volume of five-year-old preterm children are not different than full-term controls. 2021 Sep 8:S0021-7557(21)00118-2. doi: 10.1016/j.jped.2021.06.008. Online ahead of print. PMID: 34506749 
    111. Rooney K, Levy MA, Haghshenas S, Kerkhof J, Rogaia D, Tedesco MG, Imperatore V, Mencarelli A, Squeo GM, Di Venere E, Di Cara G, Verrotti A, Merla G, Tedder ML, DuPont BR, Sadikovic B, Prontera P. Identification of a DNA Methylation Episignature in the 22q11.2 Deletion Syndrome. Int J Mol Sci. 2021 Aug 10;22(16):8611. doi: 10.3390/ijms22168611. PMID: 34445317 
    112. Rosty C, Webster F, Nagtegaal ID, Driman D, on behalf of the Dataset Authoring Committee for the development of the ICCR Dataset for Pathology Reporting of Colorectal Excisional Biopsy. Pathology Reporting of Colorectal Local Excision Specimens: Recommendations from the International Collaboration on Cancer Reporting (ICCR), Gastroenterology (2021), doi: https://doi.org/10.1053/j.gastro.2021.04.066.
    113. Rutledge AC, Choi YH, Karp I, Bhayana V, Stevic I. Biochemistry tests in hospitalized COVID-19 patients: Experience from a Canadian tertiary care centre. Clin Biochem. 2021 May 19:S0009-9120(21)00149-1. doi: 10.1016/j.clinbiochem.2021.05.008. Online ahead of print. PMID: 34022172
    114. Sadikovic B, Levi MA, Kerkhof J, Aref-Eshghi E, Schenkel L, Stuart A, McConkey H, Henneman P, Venema A, Schwartz CE, Stevenson RE, Skinner SA, DuPont BR, Fletcher RS, Balci TB, Siu VM, Granadillo JL, Masters J, Kadour M, Friez MJ, van Haelst MM, Mannens MMAM, Louie RJ, Lee JA, Tedder ML, Alders M. Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders. Genet Med. 2021 Feb 5. doi: 10.1038/s41436-020-01096-4. Online ahead of print. PMID: 33547396
    115. Sadikovic B, Levy MA, Kerkhof J, Aref-Eshghi E, Schenkel L, Stuart A, McConkey H, Henneman P, Venema A, Schwartz CE, Stevenson RE, Skinner SA, DuPont BR, Fletcher RS, Balci TB, Siu VM, Granadillo JL, Masters J, Kadour M, Friez MJ, van Haelst MM, Mannens MMAM, Louie RJ, Lee JA, Tedder ML, Alders M. Correction: Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders. Genet Med. 2021 Feb 26. doi: 10.1038/s41436-021-01130-z. Online ahead of print. PMID: 33637969
    116. Salehi F, Nadeem IM, Kwan BYM, Mirsattari SM, Lee DH, Burneo JG, Steven D, Hammond R, Peters TM, Khan AR. Ultra-High Field 7-Tesla Magnetic Resonance Imaging and Electroencephalography Findings in Epilepsy. Can Assoc Radiol J. 2021 Jul 30:8465371211031802. doi: 10.1177/08465371211031802. Online ahead of print. PMID: 34328021
    117. Santyr B, Pejhan S, Zhang Q, Budhram A. Unilateral Primary Angiitis of the Central Nervous System. Ann Neurol. 2021 Sep 28. doi: 10.1002/ana.26234. Online ahead of print. PMID: 34585428
    118. Sari A, Cyr DP, Brar A, Messenger DE, Driman DK, Shivji S, Assarzadegan N, Juda A, Swallow CJ, Kennedy ED, Brar MS, Conner J, Kirsch R. Routine Elastin Staining in Surgically Resected Colorectal Cancer: Impact on Venous Invasion Detection and its Association With Oncologic Outcomes. Am J Surg Pathol. 2021 Aug 19. doi: 10.1097/PAS.0000000000001790. Online ahead of print. PMID: 34411028
    119. Schenkel LC, Aref-Eshghi E, Rooney K, Kerkhof J, Levy MA, McConkey H, Rogers RC, Phelan K, Sarasua SM, Jain L, Pauly R, Boccuto L, DuPont B, Cappuccio G, Brunetti-Pierri N, Schwartz CE, Sadikovic B. DNA methylation epi-signature is associated with two molecularly and phenotypically distinct clinical subtypes of Phelan-McDermid syndrome. Clin Epigenetics. 2021 Jan 6;13(1):2. doi: 10.1186/s13148-020-00990-7. PMID: 33407854
    120. Selvarajah S, Plante S, Speevak M, Vaags A, Hamelinck D, Butcher M, McCready E, Grafodatskaya D, Blais N, Tran-Thanh D, Weng X, Nassabein R, Greer W, Walton RN, Lo B, Demetrick D, Santos S, Sadikovic B, Zhang X, Zhang T, Spence T, Stockley T, Feilotter H, Joubert P. A Pan-Canadian Validation Study for the Detection of EGFR T790M Mutation Using Circulating Tumor DNA From Peripheral Blood. JTO Clin Res Rep. 2021 Jul 13;2(8):100212. doi: 10.1016/j.jtocrr.2021.100212. eCollection 2021 Aug. PMID: 34590051
    121. Shamiya Y, Ravi SP, Coyle A, Chakrabarti S, Paul A. Engineering nanoparticle therapeutics for impaired wound healing in diabetes. Drug Discov Today. 2021 Nov 25:S1359-6446(21)00530-4. doi: 10.1016/j.drudis.2021.11.024. PMID: 34839040
    122. Sharma AK, Joseph M, Climans SA. Isolated Leptomeningeal Recurrence of Multiple Myeloma. Neurohospitalist. 2021 Jan;11(1):87-88. doi: 10.1177/1941874420937562. Epub 2020 Jul 1. PMID: 33868566
    123. Shojaei E, Walsh JC, Sangle N, Yan B, Silverman MS, Hosseini-Moghaddam SM. Gastrointestinal Histoplasmosis Mimicking Crohn's Disease. Open Forum Infect Dis. 2021 May 16;8(7):ofab249. doi: 10.1093/ofid/ofab249. eCollection 2021 Jul. PMID: 34262987 
    124. Smith CW, Hoover D, Surry K, D'Souza D, Cool DW, Kassam Z, Bastian-Jordan M, Gomez JA, Moussa M, Chin J, Pautler S, Bauman GS, Ward AD. A multiobserver study investigating the effectiveness of prostatic multiparametric magnetic resonance imaging to dose escalate corresponding histologic lesions using high-dose-rate brachytherapy. Brachytherapy. 2021 Feb 26:S1538-4721(21)00005-2. doi: 10.1016/j.brachy.2021.01.005. Online ahead of print. PMID: 33648893
    125. Smith CW, Alfano R, Hoover D, Surry K, D'Souza D, Thiessen J, Rachinsky I, Butler J, Gomez JA, Gaed M, Moussa M, Chin J, Pautler S, Bauman GS, Ward AD. Prostate specific membrane antigen positron emission tomography for lesion-directed high-dose-rate brachytherapy dose escalation. Phys Imaging Radiat Oncol. 2021 Jul 30;19:102-107. doi: 10.1016/j.phro.2021.07.001. eCollection 2021 Jul. PMID: 34589619
    126. Su Y, Zhu C, Wang B, Zheng H, McAlister V, Lacefield JC, Quan D, Mele T, Greasley A, Liu K, Zheng X. Circular RNA Foxo3 in cardiac ischemia-reperfusion injury in heart transplantation: A new regulator and target. Am J Transplant. 2021 Sep;21(9):2992-3004. doi: 10.1111/ajt.16475. Epub 2021 Feb 2. PMID: 33382168
    127. Subasri M, Shooshtari P, Watson AJ, Betts DH. Analysis of TERT isoforms across TCGA, GTEx and CCLE datasets. Cancers, 2021. 13(8) doi:10.3390/cancers13081853
    128. Sullivan R, Randhawa VK, Lalonde T, Kiaii B, Luyt L , Wisenberg G, Dhanvantari S. Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease. CJC Open. Volume 3, Issue 2, February 2021, Pages 182-194
    129. Sullivan R, Randhawa VK, Lalonde T, Yu T, Kiaii B, Luyt L, Wisenberg G, Dhanvantari S. Regional Differences in the Ghrelin-Growth Hormone Secretagogue Receptor Signalling System in Human Heart Disease. CJC Open. 2020 Nov 4;3(2):182-194. doi: 10.1016/j.cjco.2020.10.015. eCollection 2021 Feb. PMID: 33644732
    130. Szlapinski S, Strutt B, Deane M, Arany E, Bennett J, Hill DJ. Acetone Ingestion Mimics a Fasting State to Improve Glucose Tolerance in a Mouse Model of Gestational Hyperglycemia. Int J Mol Sci. 2021 Nov 29;22(23):12914. doi: 10.3390/ijms222312914. PMID: 34884717
    131. Tierens A, Stockley TL, Campbell C, Fulcher J, Leber B, McCready E, Sabatini PJB, Sadikovic B, Schuh AC. Consensus Recommendations for MRD Testing in Adult B-Cell Acute Lymphoblastic Leukemia in Ontario. Curr Oncol. 2021 Mar 30;28(2):1376-1387. doi: 10.3390/curroncol28020131. PMID: 33808300
    132. Taher J, Randell EW, Arnoldo S, Bailey D, De Guire V, Kaur S, Knauer M, Petryayeva E, Poutanen SM, Shaw JLV, Uddayasankar U, White-Al Habeeb N, Konforte D. Canadian society of clinical chemists (CSCC) consensus guidance for testing, selection and quality management of SARS-CoV-2 point-of-care tests. Clin Biochem. 2021 May 25:S0009-9120(21)00151-X. doi: 10.1016/j.clinbiochem.2021.05.010. Online ahead of print. PMID: 34048776
    133. Thiryayi SA, Ettler H, Goebel EA, Prefontaine M, Paton TA, Wong A, Yee D, Agro E, Mayers J, Lerner-Ellis J, Turashvili G. BCOR Internal Tandem Duplication Associated Uterine Sarcoma: Expanding the Clinicopathologic Spectrum.  Int J Gynecol Pathol. 2021 Aug 30. doi: 10.1097/PGP.0000000000000822. Online ahead of print. PMID: 34456278
    134. Torres-Canchala L, Rengifo M, Filler G, Arias JC, Ramirez O, Restrepo JM. Low agreement between kidney volume and kidney length z-scores. Pediatr Nephrol. 2021 Jan 7. doi: 10.1007/s00467-020-04836-5. Online ahead of print. PMID: 33415483
    135. Tran C, Kadour M, Cecchini MJ, Leslie KA, Driman DK. Using pathology data to evaluate surgical backlogs: considerations for resource planning. CMAJ. 2021 Mar 8;193(10):E343. doi: 10.1503/cmaj.77883. PMID: 33685954
    136. Tran V, Weckman AM, Crowley VM, Cahill LS, Zhong K, Cabrera A, Elphinstone RE, Pearce V, Madanitsa M, Kalilani-Phiri L, Mwapasa V, Khairallah C, Conroy AL, Ter Kuile FO, Sled JG, Kain KC. The Angiopoietin-Tie2 axis contributes to placental vascular disruption and adverse birth outcomes in malaria in pregnancy. EBioMedicine. 2021 Nov 7;73:103683. doi: 10.1016/j.ebiom.2021.103683. Online ahead of print. PMID: 34758414
    137. Turashvili G, Colgan T, McLachlin M, Lin H, Gharbharan R. Lynch Syndrome Screening of Women With Endometrial Cancer: Feasibility and Outcomes in a Community Program. J Obstet Gynaecol Can. 2021 Oct 14:S1701-2163(21)00753-2. doi: 10.1016/j.jogc.2021.08.014. PMID: 34656766
    138. Twible C, Abdo R, Zhang Q. Astrocyte Role in Temporal Lobe Epilepsy and Development of Mossy Fiber Sprouting. Front Cell Neurosci. 2021 Sep 30;15:725693. doi: 10.3389/fncel.2021.725693. eCollection 2021. PMID: 34658792 
    139. van der Sluijs PJ, Alders M, Dingemans AJM, Parbhoo K, van Bon BW, Dempsey JC, Doherty D, den Dunnen JT, Gerkes EH, Milller IM, Moortgat S, Regier DS, Ruivenkamp CAL, Schmalz B, Smol T, Stuurman KE, Vincent-Delorme C, de Vries BBA, Sadikovic B, Hickey SE, Rosenfeld JA, Maystadt I, Santen GWE. A Case Series of Familial ARID1B Variants Illustrating Variable Expression and Suggestions to Update the ACMG Criteria. Genes (Basel). 2021 Aug 20;12(8):1275. doi: 10.3390/genes12081275. PMID: 34440449
    140. Veldhuizen RAW, Baer B, McCaig LA, Solomon LA, Cameron L, Hardy DB. The effect of maternal protein restriction during perinatal life on the inflammatory response in pediatric rats. Can J Physiol Pharmacol. 2021 May;99(5):556-560. doi: 10.1139/cjpp-2020-0431. Epub 2020 Sep 11. PMID: 32916058
    141. Volkening K, Farhan SMK, Kao J, Leystra-Lantz C, Ang LC, McIntyre A, Wang J, Hegele RA, Strong MJ. Evidence of synergism among three genetic variants in a patient with LMNA-related lipodystrophy and amyotrophic lateral sclerosis leading to a remarkable nuclear phenotype. Mol Cell Biochem. 2021 Mar 4. doi: 10.1007/s11010-021-04103-7. Online ahead of print. PMID: 33661429
    142. Voss C, Esmail S, Liu X, Knauer MJ, Ackloo S, Kaneko T, Lowes LE, Stogios PJ, Seitova A, Hutchinson A, Yusifov F, Skarina T, Evdokimova E, Loppnau P, Ghiabi P, Hajian T, Zhong S, Abdoh H, Hedley BD, Bhayana V, Martin CM, Slessarev M, Chin-Yee B, Fraser DD, Chin-Yee I, Li SS. Epitope-specific antibody responses differentiate COVID-19 outcome and variants of concern. JCI Insight. 2021 Jun 3:148855. doi: 10.1172/jci.insight.148855. Online ahead of print. PMID: 34081630
    143. Wang B, Zhou Q, Li A, Li S, Greasley A, Skaro A, Quan D, Min W, Liu K, Zheng X. Preventing alloimmune rejection using circular RNA FSCN1-silenced dendritic cells in heart transplantation. J Heart Lung Transplant. 2021 Apr 8:S1053-2498(21)02266-X. doi: 10.1016/j.healun.2021.03.025. Online ahead of print. PMID: 34052126
    144. Wang J, Ciampa G, Zheng D, Shi Q, Chen B, Abel ED, Peng T, Hall DD, Song LS. Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy. Biochem J. 2021 Oct 15;478(19):3539-3553. doi: 10.1042/BCJ20210629. PMID: 34524407
    145. Wang P, Castellani CA, Yao J, Huan T, Bielak LF, Zhao W, Haessler J, Roby J, Sun X, Guo X, Longchamps RJ, Manson JE, Grove ML, Bressler J, Taylor KD, Lappalainen T, Kasela S, Van Den Berg DJ, Hou L, Reiner A, Liu Y, Boerwinkle E, Smith JA, Peyser PA, Fornage M, Rich SS, Rotter JI, Kooperberg C, Arking DE, Levy D, Liu C; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Epigenome-wide association study of mitochondrial genome copy number. Hum Mol Genet. 2021 Aug 20:ddab240. doi: 10.1093/hmg/ddab240. Online ahead of print. PMID: 34415308
    146. Weerts MJA, Lanko K, Guzmán-Vega FJ, Jackson A, Ramakrishnan R, Cardona-Londoño KJ, Peña-Guerra KA, van Bever Y, van Paassen BW, Kievit A, van Slegtenhorst M, Allen NM, Kehoe CM, Robinson HK, Pang L, Banu SH, Zaman M, Efthymiou S, Houlden H, Järvelä I, Lauronen L, Määttä T, Schrauwen I, Leal SM, Ruivenkamp CAL, Barge-Schaapveld DQCM, Peeters-Scholte CMPCD, Galehdari H, Mazaheri N, Sisodiya SM, Harrison V, Sun A, Thies J, Pedroza LA, Lara-Taranchenko Y, Chinn IK, Lupski JR, Garza-Flores A, McGlothlin J, Yang L, Huang S, Wang X, Jewett T, Rosso G, Lin X, Mohammed S, Merritt JL 2nd, Mirzaa GM, Timms AE, Scheck J, Elting MW, Polstra AM, Schenck L, Ruzhnikov MRZ, Vetro A, Montomoli M, Guerrini R, Koboldt DC, Mosher TM, Pastore MT, McBride KL, Peng J, Pan Z, Willemsen M, Koning S, Turnpenny PD, de Vries BBA, Gilissen C, Pfundt R, Lees M, Braddock SR, Klemp KC, Vansenne F, van Gijn ME, Quindipan C, Deardorff MA, Hamm JA, Putnam AM, Baud R, Walsh L, Lynch SA, Baptista J, Person RE, Monaghan KG, Crunk A, Keller-Ramey J, Reich A, Elloumi HZ, Alders M, Kerkhof J, McConkey H, Haghshenas S; Genomics England Research Consortium, Maroofian R, Sadikovic B, Banka S, Arold ST, Barakat TS. Delineating the molecular and phenotypic spectrum of the SETD1B-related syndrome. Genet Med. 2021 Aug 3. doi: 10.1038/s41436-021-01246-2. Online ahead of print. PMID: 34345025
    147. Wiese MD, Meakin AS, Varcoe TJ, Darby JRT, Sarr O, Kiser P, Bradshaw EL, Regnault TRH, Morrison JL. Hepatic cytochrome P450 function is reduced by life-long Western diet consumption in guinea pig independent of birth weight. Life Sci. 2021 Nov 11;287:120133. doi: 10.1016/j.lfs.2021.120133. PMID: 34774623
    148. Wilton SB, Bennett MT, Parkash R, Kavanagh K, Jolicoeur EM, Halperin F, Jolly U, Leong-Sit P, Sas R, Chew DS, Singh S, Frisbee S, MacLachlan R, Manlucu J; Acute Myocardial Infarction Quality Assurance (AMIQA) Canada Investigators. Variability in Reassessment of Left Ventricular Ejection Fraction After Myocardial Infarction in the Acute Myocardial Infarction Quality Assurance Canada Study. JAMA Netw Open. 2021 Dec 1;4(12):e2136830. doi: 10.1001/jamanetworkopen.2021.36830. PMID: 34854904
    149. Yang DM, Alfano R, Bauman G, Thiessen JD, Chin J, Pautler S, Moussa M, Gomez JA, Rachinsky I, Gaed M, Chung KJ, Ward A, Lee TY. Short-duration dynamic [18F]DCFPyL PET and CT perfusion imaging to localize dominant intraprostatic lesions in prostate cancer: validation against digital histopathology and comparison to [18F]DCFPyL PET/MR at 120 minutes. EJNMMI Res. 2021 Oct 15;11(1):107. doi: 10.1186/s13550-021-00844-0. PMID: 34652551 
    150. Yang K, Reddy K, Chebib I, Hammond R, Lu JQ. Calcifying Pseudoneoplasm of the Neuraxis (CAPNON): from pathogenesis to diagnostic and therapeutic considerations. World Neurosurg. 2021 Jan 25:S1878-8750(21)00107-8. doi: 10.1016/j.wneu.2021.01.076. Online ahead of print. PMID: 33508489
    151. Yang Q, Di Cecco R, McRae S, McLachlin CM. Implementing HPV Testing for Colposcopy Patients in a Regional Centre. J Obstet Gynaecol Can. 2021 May;43(5):555-556. doi: 10.1016/j.jogc.2021.01.003. PMID: 33992127
    152. Yang K, Reddy K, Wang BH, Cenic A, Provias J, Popovic S, Yong WH, Berthelet F, Bojanowski MW, Hammond R, Lu JQ. Immunohistochemical Markers in the Diagnosis of Calcifying Pseudoneoplasm of the Neuraxis. Can J Neurol Sci. 2021 Mar;48(2):259-266. doi: 10.1017/cjn.2020.175. Epub 2020 Aug 17. PMID: 32800010
    153. Zhang M, Wang G, Peng T. Calpain-Mediated Mitochondrial Damage: An Emerging Mechanism Contributing to Cardiac Disease. Cells. 2021 Aug 8;10(8):2024. doi: 10.3390/cells10082024. PMID: 34440793
    154. Zhao CS, Yan L, He W, Ang LC, Zhang Q. Distinct subcortical tau burden: The tau pallido-claustral ratio separates progressive supranuclear palsy and corticobasal degeneration. Brain Pathol. 2021 Oct 20:e13030. doi: 10.1111/bpa.13030. PMID: 34672063
    155. Zhao J, Huang X, Mcleod P, Jiang J, Liu W, Haig A, Jevnikar AM, Jiang Z, Zhang ZX. Toll-like receptor 3 is an endogenous sensor of cell death and a potential target for induction of long-term cardiac transplant survival. Am J Transplant. 2021 Mar 30. doi: 10.1111/ajt.16584. Online ahead of print. PMID: 33784431
    156. Zheng H, Su Y, Zhu C, Quan D, Skaro AI, McAlister V, Lacefield JC, Jiang J, Xue P, Wang Y, Zheng X. An Addition of U0126 Protecting Heart Grafts From Prolonged Cold Ischemia-Reperfusion Injury in Heart Transplantation: A New Preservation Strategy. Transplantation. 2021 Feb 1;105(2):308-317. doi: 10.1097/TP.0000000000003402. PMID: 32776778
    157. Ziai H, Warner A, Mundi N, Patel K, Chung EJ, Howlett CJ, Plantinga P, Yoo J, MacNeil SD, Fung K, Mymryk JS, Barrett JW, Palma DA, Nichols AC. Does HPV Subtype Predict Outcomes in Head and Neck Cancers? Int J Otolaryngol. 2021 Feb 9;2021:6672373. doi: 10.1155/2021/6672373. eCollection 2021. PMID: 33824664
    158. Zyla R, Goebel E, Jang J-H, Turashvili G. Uterine sarcoma with FGFR1-TACC1 gene fusion: A case report and review of the literature. 2021 Int J Gynecol Pathol [Internet].

2020 Publications

    1. Abdollahi E, Champredon D, Langley JM, Galvani AP, Moghadas SM. Temporal estimates of case-fatality rate for COVID-19 outbreaks in Canada and the United States. CMAJ. 2020 Jun 22;192(25):E666-E670. doi: 10.1503/cmaj.200711. Epub 2020 May 22. PMID: 32444481
    2. Akhtar HJ, Markandey B, Ma C, Ramsewak D, Walsh JC, Jairath V. Vedolizumab Induced Clinical, Endoscopic, and Histological Improvement in Common Variable Immunodeficiency Disease-associated Intestinal Enteropathy. Inflamm Bowel Dis. 2020 Mar 4;26(4):e22-e23. doi: 10.1093/ibd/izaa012. PMID: 32002555 No abstract available.
    3. Alfano R, Bauman GS, Liu W, Thiessen JD, Rachinsky I, Pavlosky W, Butler J, Gaed M, Moussa M, Gomez JA, Chin JL, Pautler S, Ward AD. Histologic validation of auto-contoured dominant intraprostatic lesions on [18F] DCFPyL PSMA-PET imaging. Radiother Oncol. 2020 Aug 19:S0167-8140(20)30726-X. doi: 10.1016/j.radonc.2020.08.008. Online ahead of print. PMID: 32827589
    4. Alotaibi F, Figueredo R, Vincent M, Min WP, Koropatnick J. CD8+ T tumour-infiltrating lymphocytes lacking CD5 cell surface expression exhibited increased levels of activation and exhaustion. European Journal of Cancer, vol. 138, 2020, pp. S60. doi:10.1016/S0959-8049(20)31240-5.
    5. Alotaibi F, Rytelewski M, Figueredo R, Zareardalan R, Zhang M, Ferguson PJ, Maleki Vareki S, Najajreh Y, El-Hajjar M, Zheng X, Min WP, Koropatnick J. CD5 blockade enhances ex vivo CD8+ T cell activation and tumour cell cytotoxicity. Eur J Immunol. 2020 Jan 15. doi: 10.1002/eji.201948309. PMID: 31943150
    6. Alsabbagh A,Robins TL, Harriman A, Jackson-Boeters L, Darling MR, Khan ZA, McCord C. Surrogate markers for high-risk human papillomavirus infection in oral epithelial dysplasia: A comparison of p16, Ki-67, and ProExC.  Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Oct 14. pii: S2212-4403(19)31507-X. doi: 10.1016/j.oooo.2019.09.019 PMID:  31902664
    7. Altesha MA, Ni T, Khan A, Liu K, Zheng X. Circular RNA in cardiovascular disease. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar;129(3):246-259.e1. doi: 10.1016/j.oooo.2019.09.019. Epub 2019 Oct 14. PMID: 30341894
    8. Amtul Z, Randhawa J, Najdat AN, Hill DJ, Arany EJ. Correction to: Role of delayed neuroglial activation in impaired cerebral blood flow restoration following comorbid injury. Cell Mol Neurobiol. 2020 Apr;40(3):381-382. doi: 10.1007/s10571-019-00739-8. PMID: 31599387
    9. Amtul Z, Frías C, Randhawa J, Hill DJ, Arany EJ.  The spatial cerebral damage caused by larger infarct and β-amyloid toxicity is driven by the anatomical/functional connectivity. J Comp Neurol. 2020 Jan 1;528(1):48-60. doi: 10.1002/cne.24738. Epub 2019 Jul 19. PMID: 31265125
    10. Aref-Eshghi E, Biswas S, Chen C, Sadikovic B, Chakrabarti S. Glucose-induced duration-dependent genome-wide DNA methylation changes in human endothelial cells. Am J Physiol Cell Physiol. 2020 Aug 1;319(2):C268-C276. Epub 2020 May 27. doi: 10.1152/ajpcell.00011.2020. PMID: 32459505
    11. Aref-Eshghi E, Kerkhof J, Pedro VP, Barat-Houari M, Ruiz-Pallares N, Andrau J-, Lacombe D, Van-Gils J, Fergelot P, Dubourg C, Cormier-Daire V, Rondeau S, Lecoquierre F, Saugier-Veber P, Nicolas G, Lesca G, Chatron N, Sanlaville D, Vitobello A, Faivre L, Thauvin-Robinet C, Laumonnier F, Raynaud M, Alders M, Mannens M, Henneman P, Hennekam RC, Velasco G, Francastel C, Ulveling D, Ciolfi A, Pizzi S, Tartaglia M, Heide S, Héron D, Mignot C, Keren B, Whalen S, Afenjar A, Bienvenu T, Campeau PM, Rousseau J, Levy MA, Brick L, Kozenko M, Balci TB, Siu VM, Stuart A, Kadour M, Masters J, Takano K, Kleefstra T, de Leeuw N, Field M, Shaw M, Gecz J, Ainsworth PJ, Lin H, Rodenhiser DI, Friez MJ, Tedder M, Lee JA, DuPont BR, Stevenson RE, Skinner SA, Schwartz CE, Genevieve D, Sadikovic B, Groupe DI France. Evaluation of DNA methylation episignatures for diagnosis and phenotype correlations in 42 mendelian neurodevelopmental disorders. Am J Hum Genet. 2020 Mar 5;106(3):356-370. doi: 10.1016/j.ajhg.2020.01.019. Epub 2020 Feb 27. PMID: 32109418
    12. Aref-Eshghi E, McGee JD, Pedro VP, Kerkhof J, Stuart A, Ainsworth PJ, Lin H, Volodarsky M, McLachlin CM, Sadikovic B. Genetic and epigenetic profiling of BRCA1/2 in ovarian tumors reveals additive diagnostic yield and evidence of a genomic BRCA1/2 DNA methylation signature. J Hum Genet. 2020 Jun 1. doi: 10.1038/s10038-020-0780-4. [Epub ahead of print] PMID: 32483276
    13. Aref-Eshghi E, Kerkhof J, Carere DA, Volodarsky M, Bhai P, Colaiacovo S, Saleh M, Caudle M, Karp N, Prasad C, Balci T, Lin H, Campbell C, Siu VM, Sadikovic B. Clinical and technical assessment of MedExome vs. NGS panels in patients with suspected genetic disorders in Southwestern Ontario. J Hum Genet. 2020 Oct 23. doi: 10.1038/s10038-020-00860-3. Online ahead of print. PMID: 33093641
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    91. Marshall AE, Ishak CA, Dick FA. An RB-Condensin II Complex Mediates Long-Range Chromosome Interactions and Influences Expression at Divergently Paired Genes.  Mol Cell Biol. 2020 Jan 3;40(2). pii: e00452-19. doi: 10.1128/MCB.00452-19. Print 2020 Jan 3. PMID: 31685548
    92. McKinley G. Reflections on being a learner: The value of relationship-based community evaluations in indigenous communities. Can J Program Eval [Internet]. 2020;34(3):464-79.
    93. McKinley GP. We need each other: Social supports during COVID 19. Social Anthropology. 02 June 2020. https://doi.org/10.1111/1469-8676.12828
    94. McKinley, G., Fonseka, T., Nylen, K., Paul, J., Kcomt, A., and McGregor, L. Working in a Fracture Zone: Learning to Research Mental Health from Multiple Cultures. Somatophere, Special Edition: Working Definitions: Making and Unmaking “Medical Anthropology.” http://somatosphere.net/2020/fracture-zone-mental-health-research-multiple-perspectives.html/. 2020 Dec 16.     
    95. Medeiros B, Goodale D, Postenka C, Lowes LE, Kiser P, Hearn S, Salmond N, Williams KC, Allan AL. Triple-negative primary breast tumors induce supportive premetastatic changes in the extracellular matrix and soluble components of the lung microenvironment. Cancers (Basel). 2020 Jan 10;12(1). pii: E172. doi: 10.3390/cancers12010172. PMID: 31936750
    96. Mishra A, Corkum MT, Pautler SE, Wehrli B, Winquist E. Images - Solitary fibrous tumor of the prostate. Can Urol Assoc J. 2020 Jun 5. doi: 10.5489/cuaj.6289. [Epub ahead of print] PMID: 32520705
    97. Naeem A, Kubica M, Namavarian A, Pandey S, Zhang Q. A 63-year-old male with cauda equina syndrome. Brain Pathol. 2020 Mar;30(2):409-410. doi: 10.1111/bpa.12816. PMID: 32100429
    98. Nair SM, Stern N, Dewar M, Siddiqui K, Smith E, Gomez JA, Moussa M, Chin JL. Salvage open radical prostatectomy for recurrent prostate cancer following MRI-guided transurethral ultrasound ablation (TULSA) of the prostate: feasibility and efficacy. Scand J Urol. 2020 Apr 20:1-5. doi: 10.1080/21681805.2020.1752795. [Epub ahead of print] PMID: 32308085
    99. Naqash  AR, Kihn-Alarcón AJ, Stavraka C, Kerrigan K, Maleki S, Pinato DJ, and Puri S. The Role of Gut Microbiome in Modulating Response to Immune Checkpoint Inhibitor Therapy in Cancer.  Annals of Translational Medicine. 2020. In press
    100. Ndashimye E, Avino M, Olabode AS, Poon AFY, Gibson RM, Li Y, Meadows A, Tan C, Reyes PS, Kityo CM, Kyeyune F, Nankya I, Quiñones-Mateu ME, Arts EJ. Accumulation of integrase strand transfer inhibitor resistance mutations confers high-level resistance to dolutegravir in non-B subtype HIV-1 strains from patients failing raltegravir in Uganda. J Antimicrob Chemother. 2020 Aug 27:dkaa355. doi: 10.1093/jac/dkaa355. Online ahead of print. PMID: 32853364
    101. Nichols AC, Lang P, Prisman E, Berthelet E, Tran E, Hamilton S, Wu J, Fung K, de Almeida JR, Bayley A, Goldstein DP, Eskander A, Husain Z, Bahig H, Christopoulous A, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Mendez A, Winquist E, Read N, Venkatesan V, Kuruvilla S, Warner A, Mitchell S, Corsten M, Rajaraman M, Johnson-Obaseki S, Eapen L, Odell M, Chandarana S, Banerjee R, Dort J, Matthews TW, Hart R, Kerr P, Dowthwaite S, Gupta M, Zhang H, Wright J, Parker C, Wehrli B, Kwan K, Theurer J, Palma DA.  Treatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial.  BMC Cancer. 2020 Feb 14;20(1):125. doi: 10.1186/s12885-020-6607-z.  PMID: 32059705
    102. Oakie A, Zhou L, Rivers S, Cheung C, Li J, Wang R.  Postnatal knockout of beta cell insulin receptor impaired insulin secretion in male mice exposed to high-fat diet stress. Mol Cell Endocrinol. 2020 Jan 1;499:110588. doi: 10.1016/j.mce.2019.110588. Epub 2019 Sep 18.  PMID: 31541682
    103. Park SW, Bolker BM, Champredon D, Earn DJD, Li M, Weitz JS, Grenfell BT, Dushoff J. Reconciling early-outbreak estimates of the basic reproductive number and its uncertainty: framework and applications to the novel coronavirus (SARS-CoV-2) outbreak. J R Soc Interface. 2020 Jul;17(168):20200144. Epub 2020 Jul 22. doi: 10.1098/rsif.2020.0144. PMID: 32693748 
    104. Pejhan S, Mok Siu V, Ang LC, Del Bigio MR, Rastegar M. Differential brain region-specific expression of MeCP2 and BDNF in Rett Syndrome patients: A distinct grey-white matter variation. Neuropathol Appl Neurobiol. 2020 Apr 4. doi: 10.1111/nan.12619. [Epub ahead of print]. PMID: 32246495
    105. Perampalam P, Dick FA. BEAVR: A Browser-Based Tool for the Exploration and Visualization of RNA-seq Data. BMC Bioinformatics. 2020 May 29;21(1):221. doi: 10.1186/s12859-020-03549-8. PMID: 32471392
    106. Rabbani M, Hafiz A, Algadheeb M, Tugaleva E, Bergin ML, Ray Guo L-R. Pulmonary Artery Intimal Sarcoma: A Deadly Diagnosis in Disguise. CJC Open 2020.
    107. Randhawa VK, Dhanvantari S, Connelly K. How Diabetes and Heart Failure Modulate Each Other and Condition Management. Can J Cardiol. 2020 Dec 1:S0828-282X(20)31115-6. doi: 10.1016/j.cjca.2020.11.014. Online ahead of print. PMID: 33276047
    108. Restrepo JM, Torres-Canchala L, Viáfara LM, Agredo MA, Quintero AM, Filler G. Renal Length z-score for the Detection of Dysfunction in Children with Solitary Functioning Kidney. Acta Paediatr. 2020 Jun 22. doi: 10.1111/apa.15425. [Epub ahead of print] PMID: 32570288
    109. Rhudy JL, Huber F, Kuhn BL, Lannon EW, Palit S, Payne MF, Hellman N, Sturycz CA, Güereca YM, Toledo TA, Demuth MJ, Hahn BJ, Shadlow JO. Pain-related anxiety promotes pronociceptive processes in Native Americans: bootstrapped mediation analyses from the Oklahoma Study of Native American Pain Risk. Pain Rep. 2020 Jan 27;5(1):e808. doi: 10.1097/PR9.0000000000000808. eCollection 2020 Jan-Feb. PMID: 32072102
    110. Rogan P,  Mucaki E, Lu R, Shirley B, Waller E, Knoll J. Meeting Radiation Dosimetry Capacity Requirements of Population-Scale Exposures by Geostatistical Sampling. PLoS One. 2020 Apr 24;15(4):e0232008. doi: 10.1371/journal.pone.0232008. eCollection 2020. PMID: 32330192
    111. Roseborough AD, Langdon KD, Hammond R, Cipriano L, Pasternak S, Whitehead SN, Khan AR. Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates. Neuroimage Clin. 2020 Jul 6;27:102340. doi: 10.1016/j.nicl.2020.102340. Online ahead of print. PMID: 32679554
    112. Rudnick W, Science M, Thirion DJG, Abdesselam K, Choi KB, Pelude L, Amaratunga K, Comeau JL, Dalton B, Delport J, Dhami R, Embree J, Émond Y, Evans G, Frenette C, Fryters S, German G, Grant JM, Happe J, Katz K, Kibsey P, Kosar J, Langley JM, Lee BE, Lefebvre MA, Leis JA, McGeer A, Neville HL, Simor A, Slayter K, Suh KN, Tse-Chang A, Weiss K, Conly J; Canadian Nosocomial Infection Surveillance Program. Antimicrobial use among adult inpatients at hospital sites within the Canadian Nosocomial Infection Surveillance Program: 2009 to 2016. Antimicrob Resist Infect Control. 2020 Feb 13;9(1):32. doi: 10.1186/s13756-020-0684-2. PMID: 32054539
    113. Ruicci KM, Meens J, Plantinga P, Stecho W, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Howlett CJ, Boutros PC, Ailles L, Nichols AC. TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma. J Exp Clin Cancer Res. 2020 Oct 15;39(1):217. doi: 10.1186/s13046-020-01713-9. PMID: 33059733 
    114. Sadikovic B, Levy MA, Aref-Eshghi E. Functional annotation of genomic variation: DNA methylation episignatures in neurodevelopmental Mendelian disorders. Hum Mol Genet. 2020 Jul 9:ddaa144. doi: 10.1093/hmg/ddaa144. Online ahead of print. PMID: 32644126
    115. Sallam YT, Zhang Q, Pandey SK. Cortically based cystic supratentorial RELA fusion-positive ependymoma: a case report with unusual presentation and appearance and review of literature. Radiol Case Rep. 2020 Oct 2;15(12):2495-2499. doi: 10.1016/j.radcr.2020.09.022. eCollection 2020 Dec. PMID: 33033550
    116. Schünemann HJ, Ventresca M, Crowther M, Briel M, Zhou Q, Noble S, Macbeth F, Griffiths G, Garcia D, Lyman GH, Di Nisio M, Iorio A, Mbuagbaw L, Neumann I, van Es N, Brouwers M, Guyatt G, Streiff MB, Marcucci M, Baldeh T, Florez ID, Alma OG, Solh Z, Bossuyt PM, Kahale LA, Ageno W, Bozas G, Büller HR, Lebeau B, Lecumberri R, Loprinzi C, McBane R, Sideras K, Maraveyas A, Pelzer U, Perry J, Klerk C, Agnelli G, Akl EA. Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis. Lancet Haematol. 2020 Oct;7(10):e746-e755. doi: 10.1016/S2352-3026(20)30293-3. PMID: 32976752
    117. Shirley BC, Knoll JHM, Moquet J, Ainsbury E, Pham ND, Norton F, Wilkins RC, Rogan PK. Estimating partial-body ionizing radiation exposure by automated cytogenetic biodosimetry. Int J Radiat Biol. 2020 Oct 6:1-12. doi: 10.1080/09553002.2020.1820611. Online ahead of print. PMID: 32910711
    118. Shrestha Palikhe N, Wu Y, Konrad E, Gandhi VD, Rowe BH, Vliagoftis H, Cameron L. Th2 cell markers in peripheral blood increase during an acute asthma exacerbation. Allergy. 2020 Aug 4. doi: 10.1111/all.14543. Online ahead of print. PMID: 32750154
    119. Sogutdelen E, Pacoli K, Juriasingani S, Akbari M, Gabril M, Sener A. Patterns of Expression of H2S-Producing Enzyme in Human Renal Cell Carcinoma Specimens: Potential Avenue for Future Therapeutics. In Vivo. 2020 Sep-Oct;34(5):2775-2781. doi: 10.21873/invivo.12102. PMID: 32871814
    120. Squizzato A, Gallo A, Levi M, Iba T, Levy JH, Erez O, Ten Cate H, Solh Z, Gando S, Vicente V, Di Nisio M. Underlying disorders of disseminated intravascular coagulation: Communication from the ISTH SSC Subcommittees on Disseminated Intravascular Coagulation and Perioperative and Critical Care Thrombosis and Hemostasis. J Thromb Haemost. 2020 Sep;18(9):2400-2407. doi: 10.1111/jth.14946. PMID: 32881338
    121. Stewart TC, Edwards J, Penney A, Gilliland J, Clark A, Haidar T, Batey B, Pfeffer A, Fraser DD, Merritt NH, Parry NG. Evaluation of a Population Health Strategy to Reduce Distracted Driving: Examining All "Es" of Injury Prevention. J Trauma Acute Care Surg. 2020 Sep 23. doi: 10.1097/TA.0000000000002948. Online ahead of print. PMID: 32976325
    122. Su N, Poon R, Liu C, Dewan C, Darling M, Grushka M. Pain reduction in burning mouth syndrome (BMS) may be associated with selective improvement of taste: a retrospective study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May;129(5):461-467. doi: 10.1016/j.oooo.2020.02.001. Epub 2020 Mar 5. PMID: 32147381
    123. Su Y, Zhu C, Wang B, Zheng H, McAlister V, Lacefield JC, Quan D, Mele T, Greasley A, Liu K, Zheng X. Circular RNA Foxo3 in cardiac ischemia-reperfusion injury in heart transplantation: A new regulator and target. Am J Transplant. 2020 Dec 31. doi: 10.1111/ajt.16475. Online ahead of print. PMID: 33382168
    124. Surak A, Filler G, Sharma AP, Torres Canchala LA, Grattan M. Lower Prevalence of Aortic Dilatation Among Preemptive Pediatric Renal Transplant Recipients - A Cross-Sectional Cohort Study. Pediatr Transplant. 2020 May 11;e13716. doi: 10.1111/petr.13716. Online ahead of print. PMID: 32390244
    125. Suzuki M, Yokota M, Kanemitsu Y, Min WP, Ozaki S, Nakamura Y. Intranasal administration of regulatory dendritic cells is useful for the induction of nasal mucosal tolerance in a mice model of allergic rhinitis. World Allergy Organ J. 2020 Aug 11;13(8):100447. doi: 10.1016/j.waojou.2020.100447. eCollection 2020 Aug. PMID: 32817781
    126. Tai F, Chin-Yee I, Gob A, Bhayana V, Rutledge A. Reducing overutilization of serum vitamin D testing at a tertiary care centre. BMJ Open Qual, 2020 Apr 1; 9 (1): e000929, DOI: 10.1136/bmjoq-2020-000929
    127. Tao G, Miller WC, Eng JJ, Lindstrom H, Imam B, Payne M. Self-directed usage of an in-home exergame after a supervised telerehabilitation training program for older adults with lower-limb amputation. Prosthet Orthot Int. 2020 Apr;44(2):52-59. doi: 10.1177/0309364620906272. Epub 2020 Mar 1. PMID: 32114933
    128. Tao J, Rupar CA, Miller MR, Ratko S, Prasad C. Use of complementary and alternative medicine in patients with inborn errors of metabolism: A single-center study. JIMD Rep. 2019 Dec 18;51(1):105-112. doi: 10.1002/jmd2.12089. eCollection 2020 Jan. PMID: 32071845
    129. Taqui B, Asadi F, Capobianco E, Hardy DB, Jawerbaum A, Arany EJ. Olive oil diet in mild pre-gestational diabetes impacts offspring β-cell development. J Endocrinol. 2020 Jun 1. pii: JOE-20-0047.R2. doi: 10.1530/JOE-20-0047. [Epub ahead of print] PMID: 32485676
    130. Tarnopolsky MA, Kerkhof J, Stuart A, Bujak A, Nilsson MI, Hettinga B, May L, Rupar CA, Sadikovic B. Bone marrow-derived mitochondrial DNA has limited capacity for inter-tissue transfer in vivo. FASEB J. 2020 May 22. doi: 10.1096/fj.202000463R. [Epub ahead of print] PMID: 32441840
    131. Toledo TA, Kuhn BL, Payne MF, Lannon EW, Palit S, Sturycz CA, Hellman N, Güereca YM, Demuth MJ, Huber F, Shadlow JO, Rhudy JL. The Effect of Pain Catastrophizing on Endogenous Inhibition of Pain and Spinal Nociception in Native Americans: Results From the Oklahoma Study of Native American Pain Risk. Ann Behav Med. 2020 Feb 19. pii: kaaa004. doi: 10.1093/abm/kaaa004. [Epub ahead of print] PMID: 32073117
    132. Tran C, Howlett C, Driman DK. Evaluating the Impact of Lymph Node Resampling on Colorectal Cancer Nodal Stage.  Histopathology. 2020 Jul 11. doi: 10.1111/his.14209. Online ahead of print. PMID: 32654207
    133. Trelford CB, Denstedt JT, Armstrong JJ, Hutnik CML. The pro-fibrotic behavior of human Tenon’s capsule fibroblasts in medically treated glaucoma patients. Clin Ophthalmol. 2020 May 22;14:1391-1402. doi: 10.2147/OPTH.S245915. eCollection 2020. PMID: 32546947
    134. Vasanthamohan L, Choo S, Marshall T, Symons YT, Matsui D, Eastabrook G, Solh Z. Peripartum hyperhemolysis prophylaxis and management in sickle cell disease: A case report and narrative review. Transfusion. 2020 Aug 26. doi: 10.1111/trf.16003. Online ahead of print. PMID: 32851670
    135. van Es N, Ventresca M, Di Nisio M, Zhou Q, Noble S, Crowther M, Briel M, Garcia D, Lyman GH, Macbeth F, Griffiths G, Iorio A, Lawrence M, Neumann I, Brozek J, Guyatt G, Streiff MB, Baldeh T, Florez ID, Alma OG, Agnelli G, Ageno W, Marcucci M, Bozas G, Zulian G, Maraveyas A, Lebeau B, Lecumberri R, Sideras K, Loprinzi C, McBane R, Pelzer U, Riess H, Solh Z, Perry J, Kahale LA, Bossuyt PM, Klerk C, Büller HR, Akl EA, Schünemann HJ; IPDMA heparin use in cancer patients research group. The Khorana score for prediction of venous thromboembolism in cancer patients: an individual patient data meta-analysis. J Thromb Haemost. 2020 Apr 26. doi: 10.1111/jth.14824. [Epub ahead of print] PMID: 32336010
    136. Veldhuizen R, Baer B, McCaig L, Solomon LA, Cameron L, Hardy DB. The effect of maternal protein restriction during perinatal life on the inflammatory response in pediatric rats. Can J Physiol Pharmacol. 2020 Sep 11. doi: 10.1139/cjpp-2020-0431. Online ahead of print. PMID: 32916058
    137. Venner AA, Beach LA, Shea JL, Knauer MJ, Huang Y, Fung AWS, Dalton J, Provencal M, Shaw JLV. Quality assurance practices for point of care testing programs: Recommendations by the Canadian society of clinical chemists point of care testing interest group. Clin Biochem. 2021 Feb;88:11-17. doi: 10.1016/j.clinbiochem.2020.11.008. Epub 2020 Nov 29. PMID: 33264650
    138. Verma S, Chanchlani R, Siu VM, Filler G. Transient hyponatremia of prematurity caused by mild Bartter syndrome type II: a case report. BMC Pediatr. 2020 Jun 26;20(1):311. doi: 10.1186/s12887-020-02214-6. PMID: 32590952
    139. Vilos GA, Vilos AG, Hollett-Caines J, Abu-Rafea B, Jacob GP, Ettler H. Retroperitoneal pelvic tumours in women: diagnostic and therapeutic challenges. Facts Views Vis Obgyn. 2020 Mar 27;11(4):299-306. PMID: 32322825
    140. Virine B, Chande N, Driman D. Biopsies From Ascending and Descending Colon Are Sufficient for Diagnosis of Microscopic Colitis. Clin Gastroenterol Hepatol. 2020 Aug;18(9):2003-2009. doi: 10.1016/j.cgh.2020.02.036. Epub 2020 Feb 25. PMID: 32109628
    141. Volodarsky M, Kerkhof J, Stuart A, Levy M, Brady LI, Tarnopolsky M, Lin H, Ainsworth P, Sadikovic B. Comprehensive genetic sequence and copy number analysis for Charcot-Marie-Tooth disease in a Canadian cohort of 2517 patients. J Med Genet. 2020 May 6. pii: jmedgenet-2019-106641. doi: 10.1136/jmedgenet-2019-106641. [Epub ahead of print] PMID: 32376792
    142. Wang J, Qin J, Wang P, Sun Y, Zhang Q. Molecular Mechanisms of Glial Cells Related Signaling Pathways Involved in the Neuroinflammatory Response of Depression. Mediators Inflamm. 2020 Oct 10;2020:3497920. doi: 10.1155/2020/3497920. eCollection 2020. PMID: 33100903
    143. Wang L, Li Y, Wang X, Wang P, Essandoh K, Cui S, Huang W, Mu X, Liu Z, Wang Y, Peng T, Fan G. Growth differentiated factor 3 protects against endotoxin-induced cardiac dysfunction and mortality through the activation of Smad2/3 in tissue repairing macrophages. Cells 2020; 9(1). pii: E120.
    144. Wang Y, Luo W, Han J, Khan Z, Fang Q, Jin Y, Chen X, Zhang Y, Wang M, Qian J, Huang W, Lum H, Wu G, Liang G. MD2 Activation by Direct AGE Interaction Drives Inflammatory Diabetic Cardiomyopathy. Nat Commun. 2020 May 1;11(1):2148. doi: 10.1038/s41467-020-15978-3. PMID: 32358497
    145. Wilk P, Ali S, Anderson KK, Clark AF, Cooke M, Frisbee SJ, Gilliland J, Haan M, Harris S, Kiarasi S, Maltby A, Norozi K, Petrella R, Sarma S, Singh SS, Stranges S, Thind A. Geographic variation in preventable hospitalisations across Canada: a cross-sectional study. BMJ Open. 2020 May 15;10(5):e037195. doi: 10.1136/bmjopen-2020-037195. PMID: 32414831
    146. Wilson RB, Zhang R, Chen YJ, Peters KM, Sawyez CG, Sutherland BG, Patel K, Kennelly JP, Leonard KA, Jacobs RL, Wang R, Borradaile NM. Two-Week Isocaloric Time-Restricted Feeding Decreases Liver Inflammation without Significant Weight Loss in Obese Mice with Non-Alcoholic Fatty Liver Disease. Int J Mol Sci. 2020 Dec 1;21(23):E9156. doi: 10.3390/ijms21239156. PMID: 33271781
    147. Win PW, Oakie A, Li J, Wang R.  Beta-cell β1 integrin deficiency affects in utero development of islet growth and vascularization.  Cell Tissue Res. 2020 Feb 15. doi: 10.1007/s00441-020-03179-9. PMID: 32060653
    148. Yao T, Shooshtari P, Haeryfar SMM. Leveraging Public Single-Cell and Bulk Transcriptomic Datasets to Delineate MAIT Cell Roles and Phenotypic Characteristics in Human Malignancies. Front Immunol. 2020 Jul 31;11:1691. doi: 10.3389/fimmu.2020.01691. eCollection 2020. PMID: 32849590
    149. Zhang S, Chen R, Chakrabarti S, Su Z. Resident macrophages as potential therapeutic targets for cardiac ageing and injury. Clin Transl Immunology. 2020 Aug 26;9(8):e1167. doi: 10.1002/cti2.1167. eCollection 2020. PMID: 32874584
    150. Zhang M, Shi Y, Zhang Y, Wang Y, Alotaibi F, Qiu L, Wang H, Peng S, Liu Y, Li Q, Gao D, Wang Z, Yuan K, Dou F-, Koropatnick J, Xiong J, Min W. miRNA-5119 regulates immune checkpoints in dendritic cells to enhance breast cancer immunotherapy. Cancer Immunol Immunother. 2020 Feb 20. doi: 10.1007/s00262-020-02507-w. PMID: 32076794
    151. Zhang Y, Feng Y, Huang Y,  Wang Y, Qiu L, Liu Y , Peng S, Li R, Kuang N, Shi Q, Shi Y, Chen Y, Joshi R, Wang Z, Yuan K, Min W. Tumor-Targeted Gene Silencing IDO Synergizes PTT-Induced Apoptosis and Enhances Anti-tumor Immunity. Front Immunol. 2020 Jun 9;11:968. doi: 10.3389/fimmu.2020.00968. eCollection 2020. PMID: 32582152
    152. Zhang Y, Li Y, Huang X, Zhang F, Tang L, Xu S, Liu Y, Tong N, Min W. Systemic Delivery of siRNA Specific for Silencing TLR4 Gene Expression Reduces Diabetic Cardiomyopathy in a Mouse Model of Streptozotocin-Induced Type 1 Diabetes. Diabetes Ther. 2020 May;11(5):1161-1173. doi: 10.1007/s13300-020-00802-4. Epub 2020 Apr 13. PMID: 32285313
    153. Zhao D, Zheng H, Greasley A, Ling F, Zhou Q, Wang B, Ni T, Topiwala I, Zhu C, Mele T, Liu K, Zheng X. The role of miR-711 in cardiac cells in response to oxidative stress and its biogenesis: a study on H9C2 cells. Cell Mol Biol Lett. 2020 Apr 9;25:26. doi: 10.1186/s11658-020-00206-z. eCollection 2020. DOI: 10.1186/s11658-020-00206-z  PMID: 32308692
    154. Zhao D, Zheng H, Ni T, Topiwala I, McAlister V, Mele T, Liu K, Zheng X.(2020). The regulatory function of miRNA-711 by HIF-1 and NFKB in cardiomyocytes under stress.  Cellular and Molecular Research Letter. 2020, 25:26 https://doi.org/10.1186/s11658-020-00206-z 2020. Contributions: Idea generation, experimental design, data analysis, and manuscript writing and revision.
    155. Zhao X, Chen D, Szabla R, Zheng M, Li G, Du P, Zheng S, Li X, Song C, Li R, Guo JT, Junop M, Zeng H, Lin H. Broad and differential animal ACE2 receptor usage by SARS-CoV-2.  J Virol. 2020 Jul 13:JVI.00940-20. doi: 10.1128/JVI.00940-20. Online ahead of print. PMID: 32661139
    156. Zhao X, Zheng S, Chen D, Zheng M, Li X, Li G, Lin H, Chang J, Zeng H, Guo JT. LY6E Restricts the Entry of Human Coronaviruses, Including the Currently Pandemic SARS-CoV-2. J Virol. 2020 Jul 8:JVI.00562-20. doi: 10.1128/JVI.00562-20. Online ahead of print. PMID: 32641482
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2019 Publications

    1. Ahmed S, Bogiatzi C, Hackam DG, Rutledge AC, Sposato LA, Khaw A, Mandzia J, Azarpazhoo MR, Hachinski V, Spence JD. Vitamin B12 deficiency and hyperhomocysteinaemia in outpatients with stroke or transient ischaemic attack: A cohort study at an academic medical centre. BMJ Open. 2019;9(1) DOI: 10.1136/bmjopen-2018-026564. PMID: 30670531
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    83. Lucien F, Lac V, Billadeau DD, Borgida A, Gallinger S, Leong HS. Glypican-1 and glycoprotein 2 bearing extracellular vesicles do not discern pancreatic cancer from benign pancreatic diseases. Oncotarget. 2019 Feb 1;10(10):1045-1055. DOI: 10.18632/oncotarget.26620. PMID: 30800217
    84. Ma I,  Chakrabarti S, Kandel R, Allard M, Barron J, Boag A, Brooks de, Fischer G, Gaboury L, Gao Z-H, Giuere Y, Magee F, Mengel M, Potter M, Tetu M, Rizcallah E, Sadek I, Veinot J-P, Vaska M, Naugler C,. Current landscape and guide to the future of molecular diagnostic and bioinformatics training for Canadian pathology residents. Canad. J. Pathol. 11 (3): 22-39, 2019
    85. Malone ER, Saleh RR, Yu C, Ahmed L, Pugh T, Torchia J, Bartlett J, Virtanen C, Hotte SJ, Hilton J, Welch S, Robinson A, McCready E, Lo B, Sadikovic B, Feilotter H, Hanna TP, Kamel-Reid S, Stockley TL, Siu LL, Bedard PL.  OCTANE (ontario-wide cancer targeted nucleic acid evaluation): A platform for intraprovincial, national, and international clinical data-sharing.  Curr Oncol. 2019 Oct;26(5):e618-e623. doi: 10.3747/co.26.5235. Epub 2019 Oct 1. PMID: 31708655
    86. Malvankar-Mehta MS, Feng L, Hutnik CML. North American cost analysis of brand name versus generic drugs for the treatment of glaucoma.  Clinicoecon Outcomes Res. 2019; 11: 789–798.  Published online 2019 Dec 16. doi: 10.2147/CEOR.S156558  PMID: 31908505.
    87. Marshall AE, Roes MV, Passos DT, DeWeerd MC, Chaikovsky AC, Sage J, Howlett CJ, Dick FA. RB1 deletion in RB-pathway disrupted cells results in DNA damage and cancer progression. Mol Cell Biol. 2019 May 28. DOI: 10.1128/MCB.00105-19. PMID: 31138663
    88. Martin-Herranz DE, Aref-Eshghi E, Bonder MJ, Stubbs TM, Choufani S, Weksberg R, Stegle O, Sadikovic B, Reik W, Thornton JM. Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1. Genome Biol. 2019 Aug 14;20(1):146. doi: 10.1186/s13059-019-1753-9.  PMID: 31409373
    89. Miller RL, Ponte R, Jones BR, Kinloch NN, Omondi FH, Jenabian MA, Dupuy FP, Fromentin R, Brassard P, Mehraj V, Chomont N, Poon AFY, Joy JB, Brumme ZL, Routy JP, ORCHID study group. HIV diversity and genetic compartmentalization in blood and testes during suppressive antiretroviral therapy. J Virol. 2019 Jun 12. pii: JVI.00755-19. DOI: 10.1128/JVI.00755-19. PMID: 31189714
    90. Mohammadzadeh N, Love RP, Gibson R, Arts EJ, Poon AFY, Chelico L. Role of co-expressed APOBEC3F and APOBEC3G in inducing HIV-1 drug resistance. Heliyon. 2019 Apr 16;5(4):e01498. DOI: 10.1016/j.heliyon.2019.e01498. PMID: 31025011
    91. Mundi N, Prokopec SD, Ghasemi F, Warner A, Patel K, MacNeil D, Howlett C, Stecho W, Plantinga P, Pinto N, Ruicci KM, Khan MI, Han MW, Yoo J, Fung K, Sahovaler A, Palma DA, Winquist E, Mymryk JS, Barrett JW, Boutros PC, Nichols AC.  Genomic and human papillomavirus profiling of an oral cancer cohort identifies TP53 as a predictor of overall survival.  Cancers Head Neck. 2019 Dec 5;4:5. doi: 10.1186/s41199-019-0045-0. eCollection 2019.  PMID: 31844556
    92. Mura M, Cecchini MJ, Joseph M, Granton JT. Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension. Respirology. 2019 Apr 8. DOI: 10.1111/resp.13557.
    93. Naugler C, Allard M, Barron J, Boag A, Chakrabarti S, Fischer G, Gaboury L, Gao Z-H, Kandel R, Magee F, Masson J-Y, Mengel M, Potter M, Rizcallah E, Sadek I, Veinot J-P. Subspecialty sign-out in anatomic pathology: a canadian chairs of pathology position statement. Canad. J. Pathol. 11 (1): 22-27, 2019
    94. Nichols AC, Theurer J, Prisman E, Read N, Berthelet E, Tran E, Fung K, de Almeida JR, Bayley A, Goldstein DP, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Winquist E, Hammond JA, Venkatesan V, Kuruvilla S, Warner A, Mitchell S, Chen J, Corsten M, Johnson-Obaseki S, Eapen L, Odell M, Parker C, Wehrli B, Kwan K, Palma DA.  Radiotherapy versus transoral robotic surgery and neck dissection for oropharyngeal squamous cell carcinoma (ORATOR): an open-label, phase 2, randomised trial.  Lancet Oncol. 2019 Aug 12. pii: S1470-2045(19)30410-3. doi: 10.1016/S1470-2045(19)30410-3. [Epub ahead of print]  PMID: 31416685
    95. Ning S, Solh Z, Arnold DM, Morin PA. Premedication for the prevention of nonhemolytic transfusion reactions: a systematic review and meta-analysis. Transfusion. 2019 Oct 31. doi: 10.1111/trf.15566. [Epub ahead of print]  PMID: 31670424
    96. Nmezi B, Giorgio E, Raininko R, Lehman A, Spielmann M, Koenig MK, Adejumo R, Knight M, Gavrilova R, Alturkustani M, Sharma M, Hammond R, Gahl WA, Toro C, Brusco A, Padiath QS. Genomic deletions upstream of lamin B1 lead to atypical autosomal dominant leukodystrophy. Neurol Genet. 2019 Jan 24;5(1):e305. DOI: 10.1212/NXG.0000000000000305. PMID: 30842973
    97. Olabode AS, Avino M, Ng GT, Abu-Sardanah F, Dick DW, Poon AFY. Evidence for a recombinant origin of HIV-1 Group M from genomic variation. Virus Evol. 2019 Jan 22;5(1):vey039. DOI: 10.1093/ve/vey039. PMID: 30687518
    98. Palma DA, Nguyen TK, Louie AV, Malthaner R, Fortin D, Rodrigues GB, Yaremko B, Laba J, Kwan K, Gaede S, Lee T, Ward A, Warner A, Inculet R. Measuring the integration of stereotactic ablative radiotherapy plus surgery for early-stage non-small cell lung cancer: A phase 2 clinical trial. JAMA Oncol. 2019. DOI: 10.1001/jamaoncol.2018.6993. SLUG
    99. Palmer J, Poon AFY.  Phylogenetic measures of indel rate variation among the HIV-1 group M subtypes.  Virus Evol. 2019 Jul 21;5(2):vez022. doi: 10.1093/ve/vez022. eCollection 2019 Jul.  PMID: 31341641
    100. Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B. How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the canadian PNH network and review of the national registry. Eur J Haematol. 2019;102(1):36-52. DOI: 10.1111/ejh.13176. PMID: 30242915
    101. Plantinga P, Rahman S, Rizkalla K, Shepherd JG, Phua CW.  Splenic Angiosarcoma with Bone Marrow Involvement Initially Diagnosed as Systemic Mastocytosis: A Case Report.  Cureus. 2019 Sep 30;11(9):e5804. doi: 10.7759/cureus.5804.  PMID: 31720194
    102. Poon AFY, Ndashimye E, Avino M, Gibson R, Kityo C, Kyeyune F, Nankya I, Quiñones-Mateu ME, ARTS EJ, Paton NI, Walker S, Hoppe A, de Wit TFR, Sigaloff KCE, Hamers R, Boender TS, Boerma RS, Ondoa P, Nijboer M, Kroeze S, Inzaule S, Mutuluuza CK, Akanmu AS. First-line HIV treatment failures in non-B subtypes and recombinants: A cross-sectional analysis of multiple populations in uganda. AIDS Res Ther. 2019;16(1). DOI: 10.1186/s12981-019-0218-2. PMID: 30670037
    103. Qian J, Chen X, Chen X, Sun C, Jiang Y, Qian Y, Zhang Y, Khan Z, Zhou J, Liang G, Zheng C. Kaempferol reduces K63-linked polyubiquitination to inhibit nuclear factor-κB and inflammatory responses in acute lung injury in mice. Toxicol Lett. 2019;306:53-60. DOI: 10.1016/j.toxlet.2019.02.005.
    104. Quansah R, Bend JR, Armah FA, Bonney F, Aseidu J, Yawson DO, Adu MO, Luginaah I, Essumang DK, Abdul-Rahaman A, Cobbina S, Iddi S, Tersigni M, Afful S, Osei-Fosu P, Nketiah-Amponsah E.  Respiratory and non-respiratory symptoms associated with pesticide management practices among farmers in Ghana's most important vegetable hub.  Environ Monit Assess. 2019 Nov 4;191(12):716. doi: 10.1007/s10661-019-7898-x. PMID: 31686222
    105. Reid J, Wehrli B, Sowerby LJ. Spindle Cell Lipomas of the Respiratory Tract: A Case Report and Comprehensive Literature Review. Ann Otol Rhinol Laryngol. 2019 Nov;128(11):1086-1091. doi: 10.1177/0003489419862577. Epub 2019 Jul 10. Review.  PMID: 31291740
    106. Robinson LJ, Lu M, Elsayed S, Joy TR. Bilateral adrenal histoplasmosis manifesting as primary adrenal insufficiency. CMAJ. 2019 Nov 4;191(44):E1217-E1221. doi: 10.1503/cmaj.190710. PMID: 31685665
    107. Rodriguez Cuellar CI, García de la Puente S, Hernández Moraria J, Bojórquez Ochoa A, Filler G, Zaltzman Grishevich S. High depression rates among pediatric renal replacement therapy patients: A cross-sectional study.  Pediatr Transplant. 2019 Oct 4:e13591. doi: 10.1111/petr.13591. [Epub ahead of print]  PMID:  31583800
    108. Rodriguez Cuellar CI, Wang PZT, Freundlich M, Filler G. Educational review: Role of the pediatric nephrologists in the work-up and management of kidney stones. Pediatr Nephrol. 2019. DOI: 10.1007/s00467-018-4179-9
    109. Rosen LE, Fogarty U, O’Keeffe JJ, Olea Popelka F. Monitoring European badger (Meles meles) reproduction under evolving bovine tuberculosis management in Ireland. l. Eur J Wildl Res (2019) 65: 97. https://doi.org/10.1007/s10344-019-1340-0
    110. Ruicci KM, Plantinga PPinto NKhan MIStecho WDhaliwal SSYoo JFung KMacNeil DMymryk JSBarrett JWHowlett CJNichols AC. Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition. Mol Oncol. 2019 Aug 8. doi: 10.1002/1878-0261.12558. [Epub ahead of print]. PMID: 31393061
    111. Sadikovic B, Aref-Eshghi E, Levy MA, Rodenhiser D. DNA methylation signatures in mendelian developmental disorders as a diagnostic bridge between genotype and phenotype. Epigenomics. 2019 Mar 15. DOI: 10.2217/epi-2018-0192. PMID: 30875234
    112. Samuel SM, Dart A, Filler G, Bitzan M, Pinsk M, Mammen C, Nettel-Aguirre A, Perinpanayagam MA, Takano T, Chanchlani R, Zappitelli M; other members of the Canadian Childhood Nephrotic Syndrome Project Team. The Canadian childhood nephrotic syndrome (CHILDNEPH) study: report on mid-study feasibility, recruitment and main measures. BMC Nephrol. 2019 May 14;20(1):159. DOI: 10.1186/s12882-019-1320-3. PMID: 31088399
    113. Shrestha Palikhe N, Bosonea A-M, Laratta C, Gandhi VD, Nahirney D, Hillaby A, Bowen M, Bhutani M, Mayers I, Cameron L, Vliagoftis H. Stability of peripheral blood immune markers in patients with asthma. Allergy Asthma Clin Immunol. 2019;15(1). DOI: 10.1186/s13223-019-0343-4.
    114. So T, Sahovaler A, Nichols A, Fung K, Yoo J, Weir MM, MacNeil SD. Utility of clinical features with fine needle aspiration biopsy for diagnosis of Warthin tumor. J Otolaryngol Head Neck Surg. 2019 Aug 29;48(1):41. doi: 10.1186/s40463-019-0366-3.  PMID: 31464652
    115. Spence T, Stickle N, Yu C, Chow H, Feilotter H, Lo B, McCready E, Sadikovic B, Siu LL, Bedard PL, Stockley TL.  Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study. Curr Oncol. 2019 Dec;26(6):e717-e732. doi: 10.3747/co.26.5379. Epub 2019 Dec 1.  PMID: 31896942
    116. Spratt DE, Barber KR, Marlatt NM, Ngo V, Macklin JA, Xiao Y, Konermann L, Duennwald ML, Shaw GS. A subset of calcium-binding S100 proteins show preferential heterodimerization. FEBS J. 2019 May;286(10):1859-1876. doi: 10.1111/febs.14775. PMID: 30719832
    117. Staudt MD, Langdon KD, Hammond RR, Lownie, SP.  Incisional seeding of metastatic squamous cell carcinoma following carotid endarterectomy: An unusual case of an unknown primary cancer presenting as a presumed neck abscess.  Oper Neurosurg (Hagerstown). 2019 Aug 1;17(2):202-207. DOI: 10.1093/ons/opy335.  PMID:30418629
    118. Sullivan R, Randhawa VK, Stokes A, Wu D, Lalonde T, Kiaii B, Luyt L, Wisenberg G, Dhanvantari S. Dynamics of the Ghrelin/Growth Hormone Secretagogue Receptor System in the Human Heart Before and After Cardiac Transplantation. J Endocr Soc. 2019 Feb 14;3(4):748-762. DOI: 10.1210/js.2018-00393.
    119. Sung B, Su Y, Jiang J, Mcleod P, Liu W, Haig A, Green DR, Zhang ZX, Jevnikar AM.  Loss of receptor interacting protein kinases 3 and caspase-8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia-reperfusion injury.  Nephrology (Carlton). 2019 Jun;24(6):661-669. doi: 10.1111/nep.13487. Epub 2019 Apr 29.  PMID: 30175514
    120. Sy J, Ang L-C. Microtomy: Cutting formalin-fixed, paraffin-embedded sections; 2019. 269 p. DOI: 10.1007/978-1-4939-8935-5_23. PMID: 30539451
    121. Tadros M, Cabrera A, Matukas LM, Muller M. Evaluation of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry and ClinPro Tools as a Rapid Tool for Typing Streptococcus pyogenes.  Open Forum Infect Dis. 2019 Oct 11;6(11):ofz441. doi: 10.1093/ofid/ofz441. eCollection 2019 Nov. PMID: 31700941
    122. Tarnopolsky MA, Sundaram ANE, Provias J, Brady L, Sadikovic B (2019) CPEO - Like mitochondrial myopathy associated with m.8340G>A mutation. Mitochondrion 46: 69-72. DOI: 10.1016/j.mito.2018.02.008   PMID: 29501485
    123. Taylor RG, Alyamany B, Pandey S, Kertesz A, Ang LC, Finger E.  Looking Glass Syndromes: Two Sides of the Same Gene. Can J Neurol Sci. 2019 Jan;46(1):115-120. doi: 10.1017/cjn.2018.354. PMID: 30688199
    124. Tellios N, Feng M, Chen N, Liu H, Tellios V, Wang M, Li X, Chang C, Hutnik C. Mechanical stretch upregulates connexin43 in human trabecular meshwork cells. Clin Exp Ophthalmol. Epub 2019 Feb 28. DOI: 10.1111/ceo.13492. PMID: 30816600
    125. Teng X, Ji C, Zhong H, Zheng D, Ni R, Hill DJ, Xiong S, Fan G, Greer PA, Shen Z, Peng T. Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis. Diabetologia. 2019. DOI: 10.1007/s00125-019-4828-y
    126. Thomas AA, Biswas S, Feng B, Chen S, Gonder J, Chakrabarti S. lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy. Diabetologia. 2019;62(3):517-30. DOI: 10.1007/s00125-018-4797-6. PMID: 30612136
    127. Thwaites MJ, Cecchini MJ, Passos DT, Zakirova K, Dick FA. Context dependent roles for RB-E2F transcriptional regulation in tumor suppression. PLoS One. 2019 Jan 31;14(1):e0203577. doi: 10.1371/journal.pone.0203577. eCollection 2019. PMID: 30703085
    128. Tsoi VK, Bhayana V, Bombassaro AM, Tirona R, Kittanakom S. Falsely elevated vancomycin concentration in a patient not receiving vancomycin. Pharmacotherapy 2019;39(7):778-782
    129. Vilos AG, Zhu C, Abu-Rafea B, Ettler HC, Weir MM, Vilos GA.  Uterine Tumors Resembling Ovarian Sex Cord Tumors Identified at Resectoscopic Endometrial Ablation: Report of 2 Cases.  J Minim Invasive Gynecol. 2019 Jan;26(1):105-109. doi: 10.1016/j.jmig.2018.04.013. Epub 2018 Apr 24.  PMID: 29702269
    130. Vu K, Payne MWC, Hunter SW, Viana R. Risk Factors for Falls in Individuals With Lower Extremity Amputations During the Pre-Prosthetic Phase: A Retrospective Cohort Study. PM R. 2019 Aug;11(8):828-833. doi: 10.1002/pmrj.12046. Epub 2019 Apr 1. PMID: 30934158
    131. Wertheim JO, Chato C, Poon AFY. Comparative analysis of HIV sequences in real time for public health. Curr Opin HIV AIDS. 2019 Mar 5. DOI: 10.1097/COH.0000000000000539. PMID: 30882486
    132. White I, Smith S, Rizkalla K, Davies E. Unexpected Gallbladder Metastasis of Clear Cell Renal Carcinoma. Clin Pathol. 2019 Jul 22;12:2632010X19861112. doi: 10.1177/2632010X19861112. eCollection 2019 Jan-Dec. PMID: 31384752
    133. Williams KC, Cepeda MA, Javed S, Searle K, Parkins KM, Makela AV, Hamilton AM, Soukhtehzari S, Kim Y, Tuck AB, Ronald JA, Foster PJ, Chambers AF, Leong HS.  Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis.  Oncogene. 2019 May;38(19):3598-3615. doi: 10.1038/s41388-018-0667-4. Epub 2019 Jan 16.  PMID: 30651600
    134. Wong F, Al Ibrahim B, Walsh J, Qumosani K. Infliximab-induced autoimmune hepatitis requiring liver transplantation.  Clin Case Rep. 2019 Sep 27;7(11):2135-2139. doi: 10.1002/ccr3.2456. eCollection 2019 Nov. PMID: 31788265
    135. Wylie L, McConkey S. Insiders’ insight: Discrimination against indigenous peoples through the eyes of health care professionals. J Racial Ethn Health Disparities. 2019;6(1):37-45. DOI: 10.1007/s40615-018-0495-9. PMID: 29736617
    136. Xu Q, House AA, Leckie S, Gunaratnam L, Luke PP, Jevnikar AM.Patients with immunological diseases or on peritoneal dialysis are prone to false positive flow cytometry crossmatch.  Hum Immunol. 2019 Jul;80(7):487-492. doi: 10.1016/j.humimm.2019.03.015. Epub 2019 Mar 20.  PMID: 30904438
    137. Yuan Y, Chen Y, Peng T, Li L, Zhu W, Liu F, Liu S, An X, Luo R, Cheng J, Liu J, Lu Y.  Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition   Clin Sci (Lond). 2019 Aug 14;133(15):1759-1777. doi: 10.1042/CS20190672. Print 2019 Aug 15.  PMID: 31383716
    138. Yuan Y, Zhu L, Li L, Liu J, Chen Y, Cheng J, Peng T, Lu Y. S-Sulfhydration of SIRT3 by Hydrogen Sulfide Attenuates Mitochondrial Dysfunction in Cisplatin-Induced Acute Kidney Injury.  Antioxid Redox Signal. 2019 Dec;31(17):1302-1319. doi: 10.1089/ars.2019.7728. Epub 2019 Jul 17.  PMID:   31218880
    139. Zhang M, Gao D, Shi Y, Wang Y, Joshi R, Yu Q, Liu D, Alotaibi F, Zhang Y, Wang H, Li Q, Zhang ZX, Koropatnick J, Min W.  miR-149-3p reverses CD8+ T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells. Open Biol. 2019 Oct 31;9(10):190061. doi: 10.1098/rsob.190061. Epub 2019 Oct 9.  PMID: 31594465
    140. Zhanel GG, Adam HJ, Baxter MR, Fuller J, Nichol KA, Denisuik AJ, Golden AR, Hink R, Lagacé-Wiens PRS, Walkty A, Mulvey MR, Schweizer F, Bay D, Hoban DJ, Karlowsky JA; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD. 42936 pathogens from Canadian hospitals: 10 years of results (2007-16) from the CANWARD surveillance study. J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv5-iv21. doi: 10.1093/jac/dkz283. PMID: 31505641
    141. Zhao D, Shun E, Ling F, Liu Q, Warsi A, Wang B, Zhou Q, Zhu C, Zheng H, Liu K, Zheng X.  Plk2 Regulated by miR-128 Induces Ischemia-Reperfusion Injury in Cardiac Cells.  Mol Ther Nucleic Acids. 2019 Nov 30;19:458-467. doi: 10.1016/j.omtn.2019.11.029.  PMID: 31902745
    142. Zheng D, Su Z, Zhang Y, Ni R, Fan GC, Robbins J, Song LS, Li J, Peng T. Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity. Arch Toxicol. Epub 2019 Feb 27. DOI: 10.1007/s00204-019-02405-w. PMID: 30810770
    143. Zheng D, Zhang Y, Zheng M, Cao T, Wang G, Zhang L, Ni R, Brockman J, Zhong H, Fan G-C, Peng T.  Nicotinamide riboside promotes autolysosome clearance in preventing doxorubicin-induced cardiotoxicity. Clin Sci (Lond). 2019 Jul 15;133(13):1505-1521. doi: 10.1042/CS20181022. Print 2019 Jul 15. PMID:31266854
    144. Zhu C, Su Y, Juriasingani S, Zheng H, Veramkovich V, Jiang J, Sener A, Whiteman M, Lacefield J, Nagpal D, Alotaibi F, Liu K, Zheng X.  Supplementing preservation solution with mitochondria-targeted H2S donor AP39 protects cardiac grafts from prolonged cold ischemia reperfusion injury in heart transplantation. Am J Transplant. 2019 Nov; 19(11):3139-3148. doi: 10.1111/ajt.15539. Epub 2019 Sep 3. PMID: 31338943
    145. Zibrowski E, Shepherd L, Booth R, Sedig K, Gibson C. A Qualitative Study of the Theory Behind the Chairs: Balancing Lean-Accelerated Patient Flow With the Need for Privacy and Confidentiality in an Emergency Medicine Setting. JMIR Hum Factors. 2019 Feb 6;6(1):e11714. DOI: 10.2196/11714. PMID: 30724743

2018 Publications

    1. Abdelhameed M, Martir DR, Chen S, Xu WZ, Oyeneye OO, Chakrabarti S, Zysman-Colman E, Charpentier PA. Tuning the Optical Properties of Silicon Quantum Dots via Surface Functionalization with Conjugated Aromatic Fluorophores. Sci Rep. 2018 Feb 14;8(1):3050. DOI: 10.1038/s41598-018-21181-8. PMID: 29445234
    2. Adams P, Howlett C, Xenocostas A, Chakrabarti S. Sex-specific analysis post-liver transplantation in hemochromatosis with aplastic anemia and hepatocellular carcinoma. Hepatol Commun. 2017 Nov 11;2(1):13-15. DOI: 10.1002/hep4.1122. eCollection 2018 Jan. PMID: 29404507.
    3. Adeyanju K, Bend JR, Rieder MJ, Dekaban GA. HIV-1 Tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells. Virology Journal, In Press (VIRJ-D-18-00011R2).
    4. Al-Judaibi B, Hernandez-Alejandro R, Herath C, Chakrabarti S, Katherine Dokus M, Marotta P, Alghanem M. IgG4 status in explanted livers does not affect the outcome of primary sclerosing cholangitis (PSC) after liver transplant. Hepat Mon. 2018;18(7) DOI: 10.5812/hepatmon.66037
    5. Ampadu O J, Mugwaneza A R, Chakrabarti S, Long S.  Molecular mechanisms and genetic regulation in atherosclerosis. Int. J.  card. heart and vasculature 2018; 21: 36–44.  doi: 10.1016/j.ijcha.2018.09.006
    6. Amtul Z, Hill DJ, Arany EJ, Cechetto DF. Altered Insulin/Insulin-Like Growth Factor Signaling in a Comorbid Rat model of Ischemia and β-Amyloid Toxicity.Sci Rep. 2018 Mar 23;8(1):5136. DOI: 10.1038/s41598-018-22985-4. PMID: 29572520.
    7. Amtul Z, Frías C, Randhawa J, Hill DJ, Arany EJ. Spatial Dynamics of Vascular and Biochemical Injury in Rat Hippocampus Following Striatal Injury and Aβ Toxicity. Mol Neurobiol. 2019 Apr;56(4):2714-2727. DOI: 10.1007/s12035-018-1225-3.
    8. Al-Judaibi B, Hernandez-Alejandro R, Herath C, Chakrabarti S, Katherine Dokus M, Marotta P, Alghanem M. IgG4 status in explanted livers does not affect the outcome of primary sclerosing cholangitis (PSC) after liver transplant. Hepat Mon. 2018;18(7) DOI: 10.5812/hepatmon.66037
    9. Arany EJ, Waseem M, Strutt BJ, Chamson-Reig A, Bernardo A, Eng E, Hill DJ.  Direct comparison of the abilities of bone marrow mesenchymal versus hematopoietic stem cellsto reverse hyperglycemia in diabetic NOD.SCID mice.  Islets. 2018;10(4):137-150. DOI: 10.1080/19382014.2018.1480285. Epub 2018 Aug 15.  PMID: 30110202
    10. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B. The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.  Epigenetics. 2017;12(11):923-933. DOI: 10.1080/15592294.2017.1381807. Epub 2017 Nov 7.  PMID: 28933623
    11. Aref-Eshghi E, Bend EG, Hood RL, Schenkel LC, Carere DA, Chakrabarti R, Nagamani SCS, Cheung SW, Campeau PM, Prasad C, Siu VM, Brady L, Tarnopolsky MA, Callen DJ, Innes AM, White SM, Meschino WS, Shuen AY, Paré G, Bulman DE, Ainsworth PJ, Lin H, Rodenhiser DI, Hennekam RC, Boycott KM, Schwartz CE, Sadikovic B. BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes. Nat Commun. 2018 Nov 20;9(1):4885. DOI: 10.1038/s41467-018-07193-y. PMID: 30459321 PMCID: PMC6244416
    12. Aref-Eshghi E, Rodenhiser DI, Schenkel LC, Lin H, Skinner C, Ainsworth P, Pare G, Hood RL, Bulman DE, Kernohan KD, Care4Rare Canada Consortium, Boycott KM, Campeau PM, Schwartz C, Sadikovic B. Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes. Am J Hum Genet. 2018 Jan 4;102(1):156-174. DOI: 10.1016/j.ajhg.2017.12.008. PMID: 29304373.
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    93. Langdon KD, Krivosheya D, Hebb MO, Wehrli B and Ang LC.  Extracranial invasion of a recurrent, transformed anaplastic pleomorphic xanthoastrocytoma: a case report.  Volume 45, Supplement S1 (ABSTRACTS: 57th Annual Canadian Association of Neuropathologists Meeting) May 2018, pp.S2-S3
    94. Langdon KD, Cordova CA, Granter-Button S, Boyd JD, Peeling J, Murphy TH, Corbett D.  Executive dysfunction and blockage of brain microvessels in a rat model of vascular cognitive impairment.  J Cereb Blood Flow Metab. 2018 Oct;38(10):1727-1740. doi: 10.1177/0271678X17739219. Epub 2017 Oct 30  PMID: 29083274
    95. Lant JT, Berg MD, Sze DHW, Hoffman KS, Akinpelu IC, Turk MA, Heinemann IU, Duennwald ML, Brandl CJ, O'Donoghue P. Visualizing tRNA-dependent mistranslation in human cells. RNA Biol. 2018;15(4-5):567-75. DOI: 10.1080/15476286.2017.1379645. PMID: 28933646
    96. Lebo MS, Zakoor K-R, Chun K, Speevak MD, Waye JS, McCready E, Parboosingh JS, Lamont RE, Feilotter H, Bosdet I, Tucker T, Young S, Karsan A, Charames GS, Agatep R, Spriggs EL, Chisholm C, Vasli N, Daoud H, Jarinova O, Tomaszewski R, Hume S, Taylor S, Akbari MR, Lerner-Ellis J, Ainsworth P, Aronson M, Basran R, Blavier A, Blumenthal A, Boycott K, Brudno M, Buckley K, Campbell J, Campeau PM, Care M, Carson N, Carter R, Chitayat D, Chong G, Chouinard E, Craddock KJ, Docking R, Eisen A, Faghfoury H, Farrell S, Fernandez B, Fiume M, Forster-Gibson C, Friedman J, Foulkes W, Goodhand P, Gu J, Hegele R, Holter S, Horsburgh S, Hughes L, Jewett F, Junker A, Khalouei S, Knoll J, Kolomeitz E, Knoppers B, Maire G, Marshall C, Mitchell G, Moorhouse MJ, Morel C, Nelson T, Noor A, O'Connor B, O'Rielly D, Ouellette F, Racher H, Ray P, Rehm H, Riddell C, Riviere, J-B, Rosenblatt DS, Rouleau G, Ruchon A, Sabatini P, Sadikovic B, Semotiuk K, Scherer SW, Shuman C, Silver J, Siminovitch K, Solomon-Izsak L, Soucy J-F, Stavropoulos J, Stein L, Tannenbaum R, Terespolsky D, Wintle RF, Wong B, Wong N, Wang M, Watkins N, White S, Woods MO, Wyatt P, Canadian Open Genetics Repository Working Group17. Data sharing as a national quality improvement program: Reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR). (2018) Genetics in Medicine, 20 (3), pp. 294-302. DOI: 10.1038/gim.2017.80.
    97. Lebo MS, Zakoor K-R, Chun K, Speevak MD, Waye JS, McCready E, Parboosingh JS, Lamont RE, Feilotter H, Bosdet I, Tucker T, Young S, Karsan A, Charames GS, Agatep R, Spriggs EL, Chisholm C, Vasli N, Daoud H, Jarinova O, Tomaszewski R, Hume S, Taylor S, Akbari MR, Lerner-Ellis J, Ainsworth P, et. al. Canadian Open Genetics Repository Working Group17.  Data sharing as a national quality improvement program: Reporting on BRCA1 and BRCA2 variant-interpretation comparisons through the Canadian Open Genetics Repository (COGR).  Genet Med. 2018 Mar;20(3):294-302. DOI: 10.1038/gim.2017.80. Epub 2017 Jul 20.  PMID: 28726806
    98. Lee JY, Ismail OZ, Zhang X, Haig A, Lian D, Gunaratnam L. Donor kidney injury molecule-1 promotes graft recovery by regulating systemic necroinflammation. Am J Transplant. 2018 Mar 30. DOI: 10.1111/ajt.14745. [Epub ahead of print]. PMID: 29603641.
    99. Lemaster KA, Frisbee SJ, Dubois L, Tzemos N, Wu F, Lewis MT, Wiseman RW, Frisbee JC. Chronic atorvastatin and exercise can partially reverse established skeletal muscle microvasculopathy in metabolic syndrome. Am J Physiol Heart Circ Physiol. 2018;315(4):H855-70. DOI: 10.1152/ajpheart.00193.2018. PMID: 29932769
    100. Li S, Ma J, Li J-, Lacefield JC, Jones DL, Peng T-Q, Wei M. Over-expression of calpastatin attenuates myocardial injury following myocardial infarction by inhibiting endoplasmic reticulum stress. J Thorac Dis. 2018;10(9):5283-97. DOI: 10.21037/jtd.2018.08.133
    101. Lin S, Lian D, Liu W, Haig A, Lobb I, Hijazi A, Razvi H, Burton J, Whiteman M, Sener A. Daily therapy with a slow-releasing H2S donor GYY4137 enables early functional recovery and ameliorates renal injury associated with urinary obstruction. Nitric Oxide. 2018 Mar 6;76:16-28. DOI: 10.1016/j.niox.2018.03.002. [Epub ahead of print]. PMID: 29522906.
    102. Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Cancer Genome Atlas Research Network., Thorsson V, Bass AJ, Laird PW.  Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas (Parfitt, J).  Cancer Cell. 2018 Apr 9;33(4):721-735.e8. DOI: 10.1016/j.ccell.2018.03.010. Epub 2018 Apr 2.  PMID: 29622466
    103. MacLean Scott E, Solomon LA, Davidson C, Storie J, Palikhe NS, Cameron L.  Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism.  PLoS One. 2018 Jul 3;13(7):e0199156. DOI: 10.1371/journal.pone.0199156. eCollection 2018.  PMID: 29969451
    104. Mataseje LF, Boyd DA, Fuller J, Haldane D, Hoang L, Lefebvre B, Melano RG, Poutanen S, Van Caeseele P, Mulvey MR. Characterization of OXA-48-like carbapenemase producers in Canada, 2011-14. J Antimicrob Chemother. 2017 Dec 18. doi: 10.1093/jac/dkx462. [Epub ahead of print]. PMID: 29272439.
    105. Medeiros M, Lumini J, Stern N, Castañeda-Hernández G, Filler G. Generic immunosuppressants. Pediatr Nephrol. 2018;33(7):1123-31. DOI: 10.1007/s00467-017-3735-z
    106. Morrison MD, Jackson-Boeters L, Khan ZA, Shimizu MS, Franklin JH, Fung K, Yoo. JHJ, Darling MR. Identifying Candidate Biomarkers for Pleomorphic Adenoma: A Case-Control Study. Head Neck Pathol. 2018 Aug 17. DOI: 10.1007/s12105-018-0959-6. [Epub ahead of print] PubMed PMID: 30120721.
    107. Nahlawi L, Goncalves C, Imani F, Gaed M, Gomez JA, Moussa M, Gibson E, Fenster A, Ward A, Abolmaesumi P, Shatkay H, Mousavi P. Stochastic modeling of temporal enhanced ultrasound: Impact of temporal properties on prostate cancer characterization. IEEE Trans Biomed Eng. 2018;65(8):1798-809. DOI: 10.1109/TBME.2017.2778007. PMID: 29989922
    108. Ndashimye E, Avino M, Kyeyune F, Nankya I, Gibson RM, Nabulime E, Poon AFY, Kityo C, Mugyenyi P, Quiñones-Mateu ME, Arts EJ. Absence of HIV-1 drug resistance mutations supports the use of dolutegravir in uganda. AIDS Res Hum Retroviruses. 2018;34(5):404-14. DOI: 10.1089/aid.2017.0205. PMID: 29353487
    109. Noonan MM, Dragan M, Mehta MM, Hess DA, Brackstone M, Tuck AB, Viswakarma N, Rana A, Babwah AV, Wondisford FE, Bhattacharya M. The matrix protein fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion. Oncotarget. 2018;9(53):30034-52. DOI: 10.18632/oncotarget.25682
    110. Osmond A, Ashok D, Francoeur CA, Miller M, Walsh JC. Is focal active colitis of greater clinical significance in pediatric patients? A retrospective review of 68 cases with clinical correlation. Hum Pathol, 2018 Jan 20. DOI: 10.1016/j.humpath.2018.01.012. PMID: 29360496.
    111. Pacheco I, Buzea C. Nanoparticle uptake by plants – beneficial or detrimental?, invited book chapter in Phytotoxicity of nanoparticles, Editors: M. Faisal, Q. Saquib, A. A. Alatar, A.z A. Al-Khedhairy, Springer Science & Business Media, 2018.
    112. Plouffe RA, Hammond R, Goldberg HA, Chahine S. What Matters from Admissions? Identifying Success and Risk Among Canadian Dental Students.  J Dent Educ. 2018 May;82(5):515-523. DOI: 10.21815/JDE.018.057.  PMID: 29717076
    113. Poon AFY, Prodger JL, Lynch BA, Lai J, Reynolds SJ, Kasule J, Capoferri AA, Lamers SL, Rodriguez CW, Bruno D, Porcella SF, Martens C, Quinn TC, Redd AD. Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays. Retrovirology. 2018;15(1) DOI: 10.1186/s12977-018-0426-1. PMID: 29976219
    114. Poon AFY, Dearlove BL. Quantifying the aftermath: Recent outbreaks among people who inject drugs and the utility of phylodynamics. J Infect Dis. 2018;217(12):1854-7. DOI: 10.1093/infdis/jiy132 PMID: 29546389
    115. Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Gu S, Fong C, Tuck A, Youngson B, Miller N, Done SJ, Chang MC, Sengupta S, Elavathil L, Jani PA, Bonin M, Lalani N, Paszat L. Omitting radiation therapy after lumpectomy for pure DCIS does not reduce the risk of salvage mastectomy. Breast. 2018 Feb;37:181-186. DOI: 10.1016/j.breast.2017.07.002. Epub 2017 Aug 3. PMID: 28781102.
    116. Remington L, Isaacs A, Vickers D, Fuller J, and Smith S. Epidemiology of candidemia at a tertiary Canadian hospital 2004-2013. J. Assoc Med Microbiol Infect Dis. 2018 March 12;3.1:14-23.
    117. Ruicci KM, Meens J, Sun RX, Rizzo G, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Boutros PC, Ailles L, Nichols AC. A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Ka inhibition in controlling tumor growth. Int J Cancer. 2018 Nov 23. DOI: 10.1002/ijc.32009. [Epub ahead of print] PMID: 30468243
    118. Ruicci KM, Pinto N, Khan MI, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Nichols AC.  ERK-TSC2 signalling in constitutively-active HRAS mutant HNSCC cells promotes resistance to PI3K inhibition.  Oral Oncol. 2018 Sep;84:95-103. doi: 10.1016/j.oraloncology.2018.07.010.   PMID: 30115483
    119. Rutledge AB, McLeod N, Mehan N, Regan TW, Ainsworth P, Chong P, Doyle T, White M, Sanson-Fisher RW, Martin JM. A clinician-centred program for behaviour change in the optimal use of staging investigations for newly diagnosed prostate cancer. BJU Int. 2018 May;121 Suppl 3:22-27. DOI: 10.1111/bju.14144. Epub 2018 Feb 16.  PMID: 29359883.
    120. Schenkel LC, Aref-Eshghi E, Skinner C, Ainsworth P, Lin H, Paré G, Rodenhiser DI, Schwartz C, Sadikovic B. Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C. Clin Epigenetics. 2018 Feb 14;10:21. DOI: 10.1186/s13148-018-0453-8. eCollection 2018. PMID: 29456765.
    121. Silva PN, Chang HH, Arany EJ, Shukalyuk AI, Audet J, Kilkenny DM, Rocheleau JV. Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation. J Biol Chem. 2018 Sep 14. pii: jbc.RA118.003036. DOI: 10.1074/jbc.RA118.003036. [Epub ahead of print] PMID: 30217817
    122. Singh SS, Pilkerton CS, Shrader CD Jr, Frisbee SJ. Subclinical atherosclerosis, cardiovascular health, and disease risk: is there a case for the Cardiovascular Health Index in the primary prevention population?  BMC Public Health. 2018 Apr 2;18(1):429. DOI: 10.1186/s12889-018-5263-6. PMID: 29609588.
    123. Singhsnaeh A, Ang LC. Intramedullary spinal cord metastatic plasmacytoid melanoma: Case report and literature review. J Med Assoc Thailand. 2018;101(7):993-6.
    124. Shi T, Shkrum MJ. A case report of sudden death from intracardiac leiomyomatosis. Am J Forensic Med Pathol. 2018;39(2):119-22. DOI: 10.1097/PAF.0000000000000377. PMID: 29351101
    125. Solis-Reyes S, Avino M, Poon A, Kari L. An open-source k-mer based machine learning tool for fast and accurate subtyping of HIV-1 genomes. PLoS ONE. 2018;13(11):e0206409. DOI: 10.1371/journal.pone.0206409. PMID: 30427878
    126. Solh Z, Brouwers M, Florez ID. Knowledge translation in transfusion medicine. Part 1: The basics and the frameworks. Transfusion. 2018 Jan 30. DOI: 10.1111/trf.14487. [Epub ahead of print]. PMID: 29383724.
    127. Solh Z, Brouwers M, Florez ID. Knowledge translation in transfusion medicine. Part 3: Interventions and tools. Transfusion. 2018 Apr 17. DOI: 10.1111/trf.14653. [Epub ahead of print]. PMID: 29667202.
    128. Staudt MD, Langdon KD, Hammond RR, Lownie SP. Incisional Seeding of Metastatic Squamous Cell Carcinoma Following Carotid Endarterectomy: An Unusual Case of an Unknown Primary Cancer Presenting as a Presumed Neck Abscess. Oper Neurosurg (Hagerstown). 2018 Nov 10. DOI: 10.1093/ons/opy335. PMID: 30418629
    129. Sullivan R, McGirr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L, Dhanvantari S.  Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice.  J Endocr Soc. 2017 Dec 28;2(2):178-189. DOI: 10.1210/js.2017-00433. eCollection 2018 Feb 1.  PMID: 29450407
    130. Tao A, Xu X, Kvietys P, Kao R, Martin C, Rui T. Experimental diabetes mellitus exacerbates ischemia/reperfusion-induced myocardial injury by promoting mitochondrial fission: Role of down-regulation of myocardial Sirt1 and subsequent Akt/Drp1 interaction. Int J Biochem Cell Biol. 2018;105:94-103. DOI: 10.1016/j.biocel.2018.10.011
    131. Tarnopolsky MA, Sundaram ANE, Provias J, Brady L, Sadikovic B. CPEO - Like mitochondrial myopathy associated with m.8340G>A mutation. Mitochondrion. 2018 Mar 6. pii: S1567-7249(17)30331-8. DOI:10.1016/j.mito.2018.02.008. [Epub ahead of print]. PMID: 29501485.
    132. Taylor R, Alyamany B, Pandey S, Kertesz A, Ang LC, Finger E.  Two Distinct Clinical Phenotypes in a Family with ALSP Caused by a Novel CSF-1R Mutation. (P2.176)  Neurology April 10, 2018; 90 (15 Supplement)
    133. Thomas AA, Feng B, Chakrabarti S. ANRIL regulates production of extracellular matrix proteins and vasoactive factors in diabetic complications. Am J Physiol Endocrinol Metab. 2018 Mar 1;314(3):E191-E200. DOI: 10.1152/ajpendo.00268.2017. Epub 2017 Nov 7. PMID: 29118015
    134. Tong J, Fitzmaurice PS, Moszczynska A, Rathitharan G, Ang LC, Meyer JH, Mizrahi R, Boileau I, Furukawa Y, McCluskey T, Sailasuta N, Kish SJ. Normal glutathione levels in autopsied brain of chronic users of heroin and of cocaine.  Drug Alcohol Depend. 2018 Jun 23;190:20-28. DOI: 10.1016/j.drugalcdep.2018.05.021. [Epub ahead of print]  PMID: 29960919
    135. Tsoi VK, Bhayana V, Bombassaro AM, Tirona R, Betchen D, Kittanakom S. Falsely Elevated Vancomycin Concentrations in a Patient Not Receiving Vancomycin. Canadian Journal of Hospital Pharmacy; 2018. p. 58.
    136. Volkening K, Keller BA, Leystra-Lantz C, Strong MJ. RNA and protein interactors with TDP-43 in human spinal-cord lysates in amyotrophic lateral sclerosis. J Proteome Res. 2018;17(4):1712-29. DOI: 10.1021/acs.jproteome.8b00126. PMID: 29513014
    137. Walsh JC, Padgett J, Weir MM, et al.  Comparing Perceptions of Pathology as a Medical Specialty between Canadian Pathologists and Pre-clinical Medical Students.  Med.Sci.Educ. (2018). DOI: 10.1007/s40670-018-0596-4
    138. Warners MJ, Ambarus CA, Bredenoord AJ, Verheij J, Lauwers GY, Walsh JC, Katzka DA, Nelson S, van Viegen T, Furuta GT, Gupta SK, Stitt L, Zou G, Parker CE, Shackelton LM, D Haens GR, Sandborn WJ, Dellon ES, Feagan BG, Collins MH, Jairath V, Pai RK. Reliability of Histologic Assessment in Patients with Eosinophilic Oesophagitis. PMID: 29460418.
    139. Wang PZT, Prasad C, Rodriguez Cuellar CI, Filler G. Nephrological and urological complications of homozygous c.974G>A (p.Arg325Gln) OSGEP mutations. Pediatr Nephrol. 2018;33(11):2201-4. DOI: 10.1007/s00467-018-4060-x
    140. Webster-Clark M, Jaeger B, Zhong Y, Filler G, Alvarez-Elias A, Franceschini N, Díaz-González de Ferris ME.  Low agreement between modified-Schwartz and CKD-EPI eGFR in young adults: a retrospectivelongitudinal cohort study.  BMC Nephrol. 2018 Aug 6;19(1):194. DOI: 10.1186/s12882-018-0995-1.  PMID: 30081844
    141. Yousef PG, Gabril MY. An update on the molecular pathology of urinary bladder tumors.Pathol Res Pract. 2018 Jan;214(1):1-6. DOI: 10.1016/j.prp.2017.11.003. Epub 2017 Nov 10. PMID: 29254798.
    142. Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. An aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation. Neuropathol Appl Neurobiol. Letter. 2018 Feb;44(2):240-243. DOI: 10.1111/nan.12404. PMID: 28403515.
    143. Zhang Y, Zhan X, Xiong J, Peng S, Huang W, Joshi R, Cai Y, Liu Y, Li R, Yuan K, Zhou N, Min W. Temperature-dependent cell death patterns induced by functionalized gold nanoparticle photothermal therapy in melanoma cells. Sci Rep. 2018;8(1) DOI: 10.1038/s41598-018-26978-1.
    144. Zhang Y, Wang Z, Huang Y, Ying M, Wang Y, Xiong J, Liu Q, Cao F, Joshi R, Liu Y, Xu D, Zhang M, Yuan K, Zhou N, Koropatnick J, Min W. TdIF1: A putative oncogene in NSCLC tumor progression. Signal Transduct Target Ther. 2018;3(1) DOI: 10.1038/s41392-018-0030-9
    145. Zhang Y, Zhan X, Peng S, Cai Y, Zhang YS, Liu Y, Wang Z, Yu Y, Wang Y, Shi Q, Zeng X, Yuan K, Zhou N, Joshi R, Zhang M, Zhang Z, Min W. Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem. Nanomed Nanotechnol Biol Med. 2018;14(5):1679-93. DOI: 10.1016/j.nano.2018.04.010. PMID: 29684526
    146. Zhang Y, Fu J, Shi Y, Peng S, Cai Y, Zhan X, Song N, Liu Y, Wang Z, Yu Y, Wang Y, Shi Q, Fu Y, Yuan K, Zhou N, Joshi R, Ichim TE, Min W. A new cancer immunotherapy via simultaneous DC-mobilization and DC-targeted IDO gene silencing using an immune-stimulatory nanosystem. Int J Cancer. 2018;143(8):2039-52. DOI: 10.1002/ijc.31588. PMID: 29752722
    147. Zhao Y, Zurawel AA, Jenkins NP, Duennwald ML, Cheng C, Kettenbach AN, Supattapone S. Comparative analysis of mutant huntingtin binding partners in yeast species. Sci Rep. 2018;8(1) DOI: 10.1038/s41598-018-27900-5. PMID: 29934597
    148. Zhao X, Sehgal M, Hou ZF, Cheng JJ, Shu SN, Wu S, Guo F, Le Marchand SJ, Lin HX, Chang J, and Guo JT. Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses. Journal of Virology, 2018, Feb 26;92(6). DOI: 10.1128/JVI.01535-17. PMID:29263263.
    149. Zhou H and Fuller J. Recurrent Echinocandin-resistant Candida glabrata candidemia following prolonged micafungin treatment for multiple intra-abdominal abscesses: A case report. J. Assoc Med Microbiol Infect Dis. 2018 Apr 17;3.1:52-55.
    150. Zhuge W, Chen R, Guo G, Dong X, Khan Z, Sun X, Dai X, Chen X, Bao M, Shen X, Liang G. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer. Cancer Lett. 2018 Jan 1;412:46-58. DOI: 10.1016/j.canlet.2017.10.006. Epub 2017 Oct 13. PMID: 29037867.
    151. Žigman T, Petković Ramadža D, Lušić M, Zekušić M, Ninković D, Gardijan D, Potočki K, Omerza L, Beljan L, Žarković K, Kerkhof J, Ljubojević M, De Sain-Van Der Velden M, Vuković J, Fumić K, Sadiković B, Barić I. Hypogammaglobulinemia and imaging features in a patient with infantile free sialic acid storage disease (ISSD) and a novel mutation in the SLC17A5 gene. J Pediatr Endocrinol Metab. 2018;31(10):1155-9. DOI: 10.1515/jpem-2017-0397. PMID: 30243016

2017 Publications

    1. Abbott JA, Guth E, Kim C, Regan C, Siu VM, C. Rupar CA, Demeler B, Francklyn CS, Robey-Bond SM. The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity. Biochemistry. 2017 Jul 18;56(28):3619-3631. doi: 10.1021/acs.biochem.7b00114. Epub 2017 Jul 7. PMID: 28632987.
    2. Abulizi P, Loganathan N, Zhao D, Mele T, Zhang Y, Zwiep T, Liu K, Zheng X. Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide. Sci Rep. 2017 Apr 21;7(1):1037. doi: 10.1038/s41598-017-00902-5. PMID: 28432312.
    3. Adams PC, Howlett CJ. Xenocostas A. Chakrabarti S. Sex-specific analysis post liver transplantation in hemochromatosis with aplastic anemia and late onset hepatocellular carcinoma. Hepatology comm. DOI: 10.1002/hep4.1122, 2017
    4. Alturkustani M, Ang LC, Ramsay D. Pathology of toxic leucoencephalopathy in drug abuse supports hypoxic-ischemic pathophysiology/etiology. Neuropathology. 2017 Mar 9. doi: 10.1111/neup.12377. [Epub ahead of print] PMID: 28276094.
    5. Alvarez-Elías AC, Yoo EC, Todorova EK, Singh RN, Filler G. A Retrospective Study on Mycophenolic Acid Drug Interactions: Effect of Prednisone, Sirolimus, and Tacrolimus With MPA.  The Drug Monit 2017/06/01 .  39 (3) p220-228.  doi: 10.1097/FTD.0000000000000403 / PMID 28437284.
    6. Anderson PT, Gottheil S, Gabril M, Barra L, Power N. Acute urinary retention secondary to urethral involvement of granulomatosis with polyangiitis. Can Urol Assoc J. 2017 Jan-Feb;11(1-2):E38-E40. doi: 10.5489/cuaj.3555. Epub 2017 Jan 12. PMID: 28163812.
    7. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Siu V, Rodenhiser D, Schwartz C, Sadikovic B. Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders. J Mol Diagn, 2017 Aug 11, Senior Responsible Author, DOI: 10.1016/j.jmoldx.2017.07.002. PMID 28807811.
    8. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B. The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance. Epigenetics. 2017 Sep 21:0. doi: 10.1080/15592294.2017.1381807. [Epub ahead of print]. PMID 28933623.
    9. Balci TB, Hartley T, Xi Y, Dyment DA, Beaulieu CL, Bernier FP, Dupuis L, Horvath GA, Mendoza-Londono R, Prasad C, Richer J, Yang XR, Armour CM, Bareke E, Fernandez BA, McMillan HJ, Lamont RE, Majewski J, Parboosingh JS, Prasad AN, Rupar CA, Schwartzentruber J, Smith AC, Tétreault M; FORGE Canada Consortium; Care4Rare Canada Consortium, Innes AM, Boycott KM. Debunking Occam’s razor: Diagnosing multiple genetic diseases in families by whole exome sequencing. Clin Genet. 2017 Sep;92(3):281-289. doi: 10.1111/cge.12987. Epub 2017 Mar 13. PMID: 28170084.
    10. Banaschewski BJH, Baer B, Arsenault C, Jazey T, Veldhuizen EJA, Delport J, Gooyers T, Lewis JF, Haagsman HP, Veldhuizen RAW, Yamashita C. The Antibacterial and Anti-inflammatory Activity of Chicken Cathelicidin-2 combined with Exogenous Surfactant for the Treatment of Cystic Fibrosis-Associated Pathogens. Sci Rep. 2017 Nov 14;7(1):15545. doi: 10.1038/s41598-017-15558-4. PMID: 29138462.
    11. Barton M, McKelvie B, Campigotto A, Mullowney T. Legionellosis following water birth in a hot tub in a Canadian neonate. CMAJ. 2017 Oct 23;189(42):E1311-E1313. doi: 10.1503/cmaj.170711. PMID: 29061856
    12. Beamish CA, Mehta S, Strutt BJ, Chakrabarti S, Hara M, Hill DJ. Decrease in Ins+Glut2LO ß-cells with advancing age in mouse and human pancreas. J Endocrinol. 2017 Jun;233(3):229-241. doi: 10.1530/JOE-16-0475. Epub 2017 Mar 27. PMID: 28348115
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    98. Pacheco I, Buzea C. (2017) Nanomaterials toxicity. In: Advanced Environmental Analysis: Applications of Nanomaterials. Vol. 2. The Royal Society of Chemistry, ISBN: 978-1-78262-907-8. http://pubs.rsc.org/en/content/ebook/978-1-78262-907-8#!divbookcontent.
    99. Papillon-Cavanagh S, Lu C, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu OM, Dhaliwal S, Stecho W, Howlett CJ, Mymryk JS, Barrett JW, Nichols AC, Allis CD, Majewski J, Jabado N. Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas. Nature Genetics 49, 180–185 (2017) DOI:10.1038/ng.3757. PMID: 28067913.
    100. Parfitt, J. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan 12;541(7636):169-175. doi: 10.1038/nature20805. Epub 2017 Jan 4. PMID:28052061.
    101. Parfitt, J. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 Mar 16;543(7645):378-384. doi: 10.1038/nature21386. Epub 2017 Jan 23. PMID: 28112728.
    102. Pena AM, Chen S, Li X, Liang G, Chakrabarti S . Prevention of Diabetic Nephropathy by modified acidic fibroblast growth factor.  Kidney International 2017/01/01.
    103. Pena AM, Chen S, Feng B, Cai L, Li X, Liang G, Chakrabarti S. Prevention of Diabetic Nephropathy by Modified Acidic Fibroblast Growth Factor. Nephron. 2017 Jul 29. doi: 10.1159/000478745. [Epub ahead of print]. PMID: 28768285.
    104. Prasad C, Napier MP, Rupar CA, Prasad C. Fumarase deficiency: A Rare Disorder on the Cross Roads of Clinical & Metabolic Genetics, Neurology and Cancer. Dysmorphology. Clin Dysmorphol. 2017 Apr;26(2):117-120. doi: 10.1097/MCD.0000000000000148. PMID: 27541980.
    105. Qadri SM, Bissinger R, Solh Z, Oldenborg PA. Eryptosis in health and disease: A paradigm shift towards understanding the (patho)physiological implications of programmed cell death of erythrocytes. Blood Rev. 2017 Nov;31(6):349-361. doi: 10.1016/j.blre.2017.06.001. Epub 2017 Jun 17. PMID: 28669393
    106. Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Baehner FL, Miller DP, Fong C, Gu S, Tuck A, Sengupta S, Elavathil L, Jani PA, Bonin M, Chang MC, Slodkowska E, Anderson JM, Cherbavaz DB, Shak S, Paszat L. Multigene Expression Assay and Benefit of Radiotherapy After Breast Conservation in Ductal Carcinoma in Situ. J Natl Cancer Inst. 2017 Jan 29;109(4). pii: djw256. DOI: 10.1093/jnci/djw256. Print 2017 Apr. PMID: 28132956.
    107. Ratmann O, Hodcroft EB, Pickles M, Cori A, Hall M, Lycett S, Colijn C, Dearlove B, Didelot X, Frost S, Hossain AS, Joy JB, Kendall M, Kühnert D, Leventhal GE, Liang R, Plazzotta G, Poon AF, Rasmussen DA, Stadler T, Volz E, Weis C, Leigh Brown AJ, Fraser C; PANGEA-HIV Consortium. Phylogenetic Tools for Generalized HIV-1 Epidemics: Findings from the PANGEA-HIV Methods Comparison.Mol Biol Evol. 2017 Jan;34(1):185-203. doi: 10.1093/molbev/msw217. Epub 2016 Oct 7. PMID:28053012.
    108. Richard C, Wadowski M, Goruk S, Cameron L, Sharma AM, Field CJ. Individuals with obesity and type 2 diabetes have additional immune dysfunction compared with obese individuals who are metabolically healthy. BMJ Open Diabetes Research and Care, Volume 5, Issue 1, 1 May 2017, Article number e000379.  DOI:10.1136/bmjdrc-2016-000379. PMID: 28761653.
    109. Sadikovic B, Wang J, El-Hattab AW, Landsverk M, Douglas G, Brundage EK, Craigen WJ, Schmitt ES, Wong LC (2017) Correction: Sequence Homology at the Breakpoint and Clinical Phenotype of Mitochondrial DNA Deletion Syndromes. PLoS One 12: e0188610. DOI: 10.1371/journal.pone.0188610  PMID: 29155871
    110. Sadler K, Johnson M, Brunette C, Gula L, Kennard M, Charland D, Tithecott G, Rieder M, Watling C, Herbert CP, Garcia B, Hammond RR. Indigenous Student Matriculation into Medical School: Policy and Progress. The International Indigenous Policy Journal 8(1).Retrieved from: http://ir.lib.uwo.ca/iipj/vol8/iss1/5. DOI 10.18584/iipj.2017.8.1.5.
    111. Santyr BG, Goubran M, Lau JC, Kwan BYM, Salehi F, Lee DH, Mirsattari SM, Burneo JG, Steven DA, Parrent AG, de Ribaupierre S, Hammond RR, Peters TM, Khan AR. Investigation of hippocampal substructures in focal temporal lobe epilepsy with and without hippocampal sclerosis at 7T. J Magn Reson Imaging, 2017 May 1; 45 (5): 1359-1370, Coauthor, DOI: 10.1002/jmri.25447.
    112. Schenkel LC, Rodenhiser D, Siu V, McCready E, Ainsworth P, Sadikovic B. Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors. J Pediatr Genet. 2017 Mar;6(1):30-41. [Epub 2016 Nov 8] DOI: 10.1055/s-0036-1593849 PMID: 28180025.
    113. Schenkel LC, Kernohan KD, McBride A, Reina D, Hodge A, Ainsworth PJ, Rodenhiser DI, Pare G, Bérubé NG, Skinner C, Boycott KM, Schwartz C, Sadikovic B. Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome. Epigenetics Chromatin. 2017 Mar 10;10:10. doi: 10.1186/s13072-017-0118-4. eCollection 2017 Mar 10. PMID: 28293299.
    114. Shi T, Wehrli BM. Monophasic Synovial Sarcoma of the Hypopharynx Excised by Transoral Laser Microsurgery.  Journal of Laryngology and Voice 2017/01/01. 
    115. Shirley B, Li Y, Knoll JHM, Rogan PK. Expedited radiation biodosimetry by automated dicentric chromosome identification and dose estimation, J Vis Exp. 2017 Sep 4;(127). doi: 10.3791/56245. PMID: 28892030.
    116. Srigley JA, Pelude L, Thampi N, Vayalumkal J, Amaratunga K, Bush K, Collet JC, Ellis C, Embree J, Forrester L, Frenette C, Henderson E, John MA, Johnston BL, Langley JM, Lee BE, Lefebvre M-A, Lemieux C, McGeer A, Noseworthy E, Quach C, Richardson S, Scien . Central Line-Associated Bloodstream Infections in Canadian Pediatric and Neonatal Intensive Care Units: 2009-2015.  Association of Medical Microbiology and Infectious Diseases Canada 2017/05/04.  
    117. Sullivan R, Mc Girr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L,  Dhanvantari S. Changes in the cardiac GHSR1a-Ghrelin system correlate with myocardial dysfunction in diabetic cardiomyopathy in mice.  Journal of the Endocrine Society. 2017 Dec 28;2(2):178-189. doi: 10.1210/js.2017-00433. eCollection 2018 Feb 1. PMID: 29450407
    118. Tahmasebi H, Higgins V, Fung AWS, Truong D, White-Al Habeeb NMA, Adeli K. Pediatric Reference Intervals for Biochemical Markers: Gaps and Challenges, Recent National Initiatives and Future Perspectives.  EJIFCC 2017/03/01: 28 (1) p43-63.  / PMID 28439218.
    119. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan 12;541(7636):169-175. doi: 10.1038/nature20805. Epub 2017 Jan 4. PMID:28052061.
    120. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 Mar 16;543(7645):378-384. doi: 10.1038/nature21386. Epub 2017 Jan 23. PMID: 28112728.
    121. Thomas AA, Feng B, Chakrabarti S. ANRIL: A Regulator of VEGF in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):470-480. doi:10.1167/iovs.16-20569. PMID: 28122089.
    122. Thwaites M J, Cecchini MJ, Talluri S, Passos DT, Carnevale J, Dick FA. Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control. Cell Div. 2017; 12: 3. PMCID: PMC5348811 DOI: 10.1186/s13008-017-0029-6.
    123. Tijssen JA, Filler G. When CRRT on ECMO Is Not Enough for Potassium Clearance: A Case Report.  Can J Kidney Health Dis 2017/01/01: 4 p2054358117722559.  doi: 10.1177/2054358117722559 / PMID 28856008.
    124. Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ. Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders. Brain. 2017 Sep 1;140(9):2460-2474. doi: 10.1093/brain/awx172. PMID: 29050386
    125. Tota JE, Bentley J, Blake J, Coutlée F, Duggan MA, Ferenczy A, Franco EL, Fung-Kee-Fung M, Gotlieb W, Mayrand MH, McLachlin M, Murphy J, Ogilvie G, Ratnam S. Introduction of molecular HPV testing as the primary technology in cervical cancer screening: Acting on evidence to change the current paradigm. Prev Med. 2017 May;98:5-14. doi: 10.1016/j.ypmed.2016.11.029. Epub 2017 Feb 6. PMID: 28279264.
    126. Tota JE, Bentley J, Blake J, Coutlée F, Duggan MA, Ferenczy A, Franco EL, Fung-Kee-Fung M, Gotlieb W, Mayrand MH, McLachlin M, Murphy J, Ogilvie G, Ratnam S. Approaches for triaging women who test positive for human papillomavirus in cervical cancer screening. Prev Med. 2017 May;98:15-20. doi: 10.1016/j.ypmed.2016.11.030. Epub 2017 Feb 6. PMID: 28279257.
    127. Wang L, Huang Z, Huang W, Chen X, Shan P, Zhong P, Khan Z, Wang J, Fang Q, Liang G, Wang Y. Inhibition of epidermal growth factor receptor attenuates atherosclerosis via decreasing inflammation and oxidative stress. Sci Rep. 2017 Apr 4;8:45917. doi: 10.1038/srep45917. PMID: 28374780.
    128. White-Al Habeeb NM. Downregulation of PDZ Domain Containing 1 (PDZK1) is a Poor Prognostic Marker for Clear Cell Renal Cell Carcinoma.  EBioMedicine 2017/02/01: 16 p20-21.  doi: 10.1016/j.ebiom.2017.01.012 / PMID 28109828.
    129. White-Al Habeeb NMA, Earle T, Spencer M, Blasutig IM. Evaluation of the N-latex serum free light chain assay on the Siemens BNII analyzer and agreement with The Binding Site FreeLite assay on the SPAPlus.  Clin Biochem 2017/05/13:  doi: 10.1016/j.clinbiochem.2017.05.009 / PMID 28512013.
    130. Yan B, Feagan B, Teriaky A, Mosli M, Mohamed R, Williams G, Yeung E, Yong E, Haig A, Sey M, Stitt L, Zou GY, Jairath V. Reliability of EUS indices to detect inflammation in ulcerative colitis.Gastrointest Endosc. 2017 Jul 29. pii: S0016-5107(17)32158-2. doi: 10.1016/j.gie.2017.07.035. [Epub ahead of print]. PMID 28760533
    131. Yildirim ZK, Nexo E, Rupar T, Büyükavci M. Seven Patients With Transcobalamin Deficiency Diagnosed Between 2010 and 2014: A Single-Center Experience. J Pediatr Hematol Oncol. 2017 Jan;39(1):38-41. PMID: 27824740.
    132. Yu J, Elsayed S, Sun D. A 44-year-old man with acute asymmetric polyarthritis and fever. CMAJ. 2017 Jun 26;189(25):E861-E864. doi: 10.1503/cmaj.170093. DOI: 10.1503/cmaj.170093 PMID: 28652481
    133. Zhang Y, Moszczynski LA, Liu Q, Jiang J, Zhao D, Quan D, Mele T, McAlister V, Jevnikar A, Baek SJ, Liu K, Zheng X. Growth Differentiation Factor 15 (GDF15) Preventing Cold Ischemia Reperfusion Injury (I/R) in Heart Transplantation through Foxo3a Signaling. Oncotarget. 2017 May 30; 8(22):36531- 36544. doi: 10.18632/oncotarget.16607. PMID: 28388574
    134. Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. an aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation.Neuropathol Appl Neurobiol. 2017 Apr 12. doi: 10.1111/nan.12404. [Epub ahead of print]. PMID: 28403515.
    135. Zhang Y, Zhang G, Liu Y, Chen R, Zhao D, McAlister V, Mele T, Liu K, Zheng X. GDF15 Regulates Malat-1 Circular RNA and Inactivates NFκB Signaling Leading to Immune Tolerogenic DCs for Preventing Alloimmune Rejection in Heart Transplantation. Front Immunol. 2018 Oct 30; 9:2407. doi: 10.3389/fimmu.2018.02407. eCollection 2018. PMID: 30425709
    136. Zou C, Li W, Li J, Khan ZA, Pan Y, Wu X, Yin H, Wang J, Zheng C, Liang G. 11β-HSD1 inhibition ameliorates diabetes-induced cardiomyocyte hypertrophy and cardiac fibrosis through modulation of EGFR activity. Oncotarget. 2017 Oct 24;8(56):96263-96275. doi: 10.18632/oncotarget.22015. eCollection 2017 Nov 10. PMID: 29221204.

2016 Publications

    1. Schenkel LC, Schwartz C, Skinner C, Rodenhiser DI, Ainsworth PJ, Pare G, Sadikovic B.  Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.  J Mol Diagn. 2016 Nov;18(6):834-841.  doi: 10.1016/j.jmoldx.2016.06.005.  PMID: 27585064
    2. Schenkel LC, Rodenhiser DI, Ainsworth PJ, Paré G, Sadikovic B.  DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.  Crit Rev Clin Lab Sci. 2016;53(3):147-65.  DOIi: 10.3109/10408363.2015.1113496. Review.  PMID: 26758403
    3. Kernohan KD, Cigana Schenkel L, Huang L, Smith A, Pare G, Ainsworth P; Care4Rare Canada Consortium., Boycott KM, Warman-Chardon J, Sadikovic B.  Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy.  Clin Epigenetics. 2016 Sep 5;8:91. doi: 10.1186/s13148-016-0254-x.  PMID: 27602171 Free PMC Article
    4. Hood RL, Schenkel LC, Nikkel SM, Ainsworth PJ, Pare G, Boycott KM, Bulman DE, Sadikovic B. The defining DNA methylation signature of Floating-Harbor Syndrome. Sci Rep, 2016 Dec 9; 6: 38803.  DOI: 10.1038/srep38803. PMID 27934915.
    5. Iqbal J, Nussenzweig A, Lubinski J, Byrski T, Eisen A, Bordeleau L, Tung NM, Manoukian S, Phelan CM, Sun P, Narod SA, Hereditary Breast Cancer Research Group (incl. Ainsworth P). The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study. Br J Cancer, 2016 May 10; 114 (10): 1160-4.  DOI: 10.1038/bjc.2016.58. PMID 26986251.
    6. Gronwald J, Glass K, Rosen B, Karlan B, Tung N, Neuhausen SL, Moller P, Ainsworth P, Sun P, Narod SA, Lubinski J, Kotsopoulos J, Hereditary Breast Cancer Clinical Study Group. Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. Fertil Steril. 2016 Mar 1, 105. (3): p.781-5.  DOI: 10.1016/j.fertnstert.2015.11.034. PMID 26698676
    7. Florendo-Cumbermack A, Selchen D, Morrow SA, Sharma M, Steven D, Ang LC, Casserly C, Burneo J, Kremenchutzky M, Hammond R.   Everything Old is New Again.  Can J Neuro Sci.  Volume 43, Issue 1, 5 Jan 2016, Pages 213-218  DOI:  10.1017/cjn.2015.309
    8. Mattingly TK, Denning LM, Siroen KL, Lehrbass B, Lopez-Ojeda P, Stitt L, Pelz DM, Das S, Ang LC, Lee DH, Lownie SP. Catheter based selective hypothermia reduces stroke volume during focal cerebral ischemia in swine. J Neurointerv Surg. 2016 Apr;8(4):418-22. doi: 10.1136/neurintsurg-2014-011562. Epub 2015 Feb 12. PMID: 25676148
    9. Tong J, Fitzmaurice PS, Moszczynska A, Mattina K, Ang LC, Boileau I, Furukawa Y, Sailasuta N, Kish SJ. Do glutathione levels decline in aging human brain? Free Radic Biol Med, 2016 Apr; 93: 110-7. Doi: 10.1016/j.freeradbiomed.2016.01.029.
    10. Alturkustani M, Ang LC. Acute hypoxic-ischemia in cardiac arrest encephalopathy causes only minimal demyelination. Neuropathology 2016 Mar; doi:10.1111/neup.12287.
    11. Beamish CA, Strutt BJ, Arany EJ, Hill DJ. Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters. Islets. 2016 Mar 24:e1162367. [Epub ahead of print] PMID: 27010375
    12. Whitehead R, Guan H, Arany E, Cernea M, Yang K.  Prenatal exposure to bisphenol A alters mouse fetal pancreatic morphology and islet composition.  Horm Mol Biol Clin Investig.  2016 Mar;25(3):171-9. DOI: 10.1515/hmbci-2015-0052  PMID: 26812801.

    13. Quansah R, Bend JR, Abdul-Rahaman A, Armah FA, Luginaah I, Essumang DK, Iddi S, Chevrier J, Cobbina SJ, Nketiah-Amponsah E, Adu-Kumi S, Darko G, Afful S. Associations between pesticide use and respiratory symptoms: A cross-sectional study in Southern Ghana. Environ Res. 2016 Jun 16;150:245-254. doi: 10.1016/j.envres.2016.06.013. PMID: 27318967
    14. Palikhe NS, Laratta C, Nahirney D, Vethanayagam D, Bhutani M, Vliagoftis H, Cameron L. Elevated levels of circulating CD4(+) CRTh2(+) T cells characterize severe asthma. Clin Exp Allergy, 2016 Jun;46(6):825-36. DOI: 10.1111/cea.12741  PMID:  27079298.
    15. Ethier C, Yu Y, Cameron L, Lacy P, Davoine F.  Calcitriol Reduces Eosinophil Necrosis Which Leads to the Diminished Release of Cytotoxic Granules.  Int Arch Allergy Immunol. 2016;171(2):119-129. DOI: 10.1159/000450951. Epub 2016 Dec 1.  PMID:  27902981

    16. Campigotto A, Muller MP, Taggart LR, Haj R, Leung E, Nadarajah J, Matukas LM. Cumulative Antimicrobial Susceptibility Data from Intensive Care Units at One Institution: Should Data Be Combined? J Clin Microbiol, 2016 Apr 1; 54 (4): 956-9.  DOI: 10.1128/JCM.02992-15.

    17. Campigotto A, Richardson SE, Sebert M, McElvania TeKippe E, Chakravarty A, Doern CD. 2016. Low utility of pediatric isolator blood culture system for detection of fungemia in children: a 10-year review. J Clin Microbiol 54:2284–2287. DOI: 10.1128/JCM.00578-16.
    18. Thwaites MJ, Cecchini MJ, Passos DT, Welch I, Dick FA.  Interchangeable roles for E2F transcriptional repression by the retinoblastoma protein and p27KIP1-CDK regulation in cell cycle control and tumor suppression.  Mol Cell Biol. 2016 Nov 7. pii: MCB.00561-16. [Epub ahead of print]  DOI: 

      10.1128/MCB.00561-16  PMID:.27821477
    19. Ishak CA, Marshall AE, Passos DT, White CR, Seung KJ , Cecchini MJ, Ferwati S, MacDonald WA, Howlett CJ, Welch ID, Rubin SM, Mann MRW, Dick FA.  An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences.  Mol Cell Biol. 2016 Nov 23. [Epub ahead of print]  DOI:  10.1016/j.molcel.2016.10.021

    20. Chakrabarti S. MicroRNA15a- A Molecule Modulating Multiple Pathologies in Diabetic Retinopathy. (Invited commentary). EBioMedicine. 2016 Sep;11:13-14. doi: 10.1016/j.ebiom.2016.08.017. Epub 2016 Aug 13. PMID: 27546691

    21. Gordon A, Feng B, Chakrabarti S Long Non-coding RNA malat-1 regulates inflammatory cytokines in chronic diabetic complications. Diabetes 2016 Jun; 65 (Supplement 1), A137/525-P
    22. Feng B, Chen S, Gordon A, Chakrabarti S. Antiinflammatory and antifibrotic effects of endothelial miRNA146 in the heart in diabetes. Diabetes 2016 Jun; 65 (Supplement 1); A125/474-P.
    23. Li B, Iordanous Y, Chakrabarti S, Alan LH, Adenoid Cystic Carcinoma Presenting as a Retro-orbital mass, Can J Ophthalmol. 2016 Apr;51(2):e65-7. doi: 10.1016/j.jcjo.2015.12.012.
    24. Feng B, Cao Y, Chen S, Chu X, Chu Y, Chakrabarti S. miR-200b mediates endothelial to mesenchymal transition in diabetic cardiomyopathy. Diabetes. 2016 Mar;65(3):768-79. doi: 10.2337/db15-1033. Epub 2015 Dec 30. PMID: 26718496
    25. Zhang Q, Hussey A, Ubaidat M, Chan N, Gomez JA. Malignant Mesothelioma of the Tunica Vaginalis Testis: A Case Report and Review of Literature. Canadian Journal of Pathology 2016/03/01 19-23 .
    26. Ostrakhovitch EA, Song YP,  Cherian MG. Basal and copper-induced expression of metallothionein isoform 1,2 and 3 genes in epithelial cancer cells: The role of tumor suppressor P53. Journal of Trace Elements in Medicine and Biology Volume 35, May 2016, Pages 18–29 DOI: 10.1016/j.jtemb.2016.01.008.
    27. Chin-Yee B, Lazo-Langner A, Butler-Foster T, Hsia C, Chin-Yee I. Blood donation and testosterone replacement therapy. Transfusion. 2017 Mar;57(3):578-581. doi: 10.1111/trf.13970. Epub 2017 Feb 1. PMID: 28150363.
      Parviz Y, Hsia C, Alemayehu M, Wall S, Bagur R, AbuRomeh N, Chin-Yee I, Lavi S. The effect of fresh versus standard blood transfusion on microvascular endothelial function. Am Heart J. 2016 Nov;181:156-161. doi: 10.1016/j.ahj.2016.05.021. Epub 2016 Aug 26. PMID: 27823688.
    28. Hsia CC, Mahon JL, Seitelbach M, Chia J, Zou G, Chin-Yee IH. Use of n-of-1 (single patient) trials to assess the effect of age of transfused blood on health-related quality of life in transfusion-dependent patients. Transfusion, 2016 May 1; 56 (5): 1192-200.  DOI: 10.1111/trf.13484. PMID 26840915

    29. Louzada ML, Hsia CC, Al-Ani F, Ralley F, Xenocostas A, Martin J, Connelly SE, Chin-Yee IH, Minuk L, Lazo-Langner A. Randomized double-blind safety comparison of intravenous iron dextran versus iron sucrose in an adult non-hemodialysis outpatient population: A feasibility study. BMC Hematol, 2016 Jan 1; 16: 7.  DOI: 10.1186/s12878-016-0046-8. PMID 26973791
    30. da Silveira Cavalcante L, Feng Q, Chin-Yee I, Acker JP, Holovati JL. Effect of liposome-treated red blood cells in an anemic rat model. J Liposome Res, 2016 Apr 8: 1-8.  DOI: 10.3109/08982104.2016.1149867. PMID 27055898
    31. Gupta M, Copley K, Keeney M, Chin-Yee I.  Does Cell Size Matter?: Utilizing Mean Cell Volume in Hospitalized Patients As a Screen to Determine Common Causes of Anemia Including Iron Deficiency Anemia, Vitamin B12 and Folate Deficiency. Blood. 2016 Dec:128(22):2338
    32. Gottheil S, Khemani E, Copley K, Keeney M, Kinney J, Chin-Yee I, Gob A. Reducing inappropriate ESR testing with computerized clinical decision support. BMJ Qual Improv Rep, 2016 Jan 1; 5 (1).  DOI: 10.1136/bmjquality.u211376.w4582. PMID 27096092
    33. Delport JA, Mohorovic I, Lannigan R, Burn S, McCormick JK, Conkey B, MacDonald K, Schaus DG, John MA. Rapid Detection of Methicillin Resistant Staphylococcus aureus (MRSA) Bacteremia Using A Combined Three Hour Short-Incubation MALDI-TOF Identification and the Alere Culture Colony Test PBP2a Detection Test. J Med Microbiol. 2016 May 23. DOI: 10.1099/jmm.0.000285. [Epub ahead of print].  PMID:  27221546
    34. Delport JA, Strikwerda A, Armstrong A, Schaus D, John M. Quality of Care Is Improved by Rapid Short Incubation MALDI-ToF Identification from Blood Cultures as Measured by Reduced Length of Stay and Patient Outcomes as Part of a Multi-Disciplinary Approach to Bacteremia in Pediatric Patients. PLoS One, e0160618. DOI: 10.1371/journal.pone.0160618. PMID 27513860.
    35. Chadwick SR, Pananos AD, Di Gregorio SE, Park AE, Etedali-Zadeh P, Duennwald ML, Lajoie P. A Toolbox for Rapid Quantitative Assessment of Chronological Lifespan and Survival in Saccharomyces cerevisiae. Traffic, 2016 Jun 1; 17 (6): 689-703  DOI: 10.1111/tra.12391  PMID 26939796.
    36. Hoffmann KS, Duennwald ML, Karagiannis J, Genereaux J, McCarton AS, Brandl CJ. Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response. G3 (Bethesda), 2016 Apr 6  DOI: 10.1534/g3.116.029520  PMID 27172216.
    37. Jiang Y, Di Gregorio SE, Duennwald ML, Lajoie P. Polyglutamine toxicity in yeast uncovers phenotypic variations between different fluorescent protein fusions. Traffic. 2016 Oct 13. doi: 10.1111/tra.12453. PMID:27734565.
    38. Zurawel AA, Kabeche R, DiGregorio SE, Deng L, Menon KM, Opalko H, Duennwald ML, Moseley JB, Supattapone S. CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins. MBio. 2016 Sep 27;7(5). pii: e01367-16. doi: 10.1128/mBio.01367-16. PMID: 27677791

    39. Leach MD, Kim T, DiGregorio S, Collins C, Zhang Z, Duennwald ML, Cowen LE. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda). 2016 Nov 2. pii: g3.116.035675. doi: 10.1534/g3.116.035675. [Epub ahead of print] PMID:27807047

    40. Carroll CS, Amankwa LN, Pinto LJ, Fuller JD, Moore MM. Detection of a Serum Siderophore by LC-MS/MS as a Potential Biomarker of Invasive Aspergillosis. PLoS One 2016 Mar 14;11(3):e0151260 DOI:  10.1371/journal.pone.0151260  PMID:  26974544
    41. Charles MK, Berenger BM, Turnbull L, Rennie R, Fuller J. Variability of β-lactam susceptibility testing for Streptococcus pneumoniae using 4 commercial test methods and broth microdilution. Diagn Microbiol Infect Dis 2016 Mar;84(3):240-5 DOI:  10.1016/j.diagmicrobio.2015.11.014 PMID:  26707068
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    119. Zheng X, Zang G, Jiang J, He W, Johnston NJ, Ling H, Chen R, Zhang X, Liu Y, Haig A, Luke P, Jevnikar AM, Min WP. Attenuating Ischemia-Reperfusion Injury in Kidney Transplantation by Perfusing Donor Organs With siRNA Cocktail Solution. Transplantation. 2016 Apr;100(4):743-52. doi: 10.1097/TP.0000000000000960.

2015 Publications

    1. Cybulski C, Lubinski J, Huzarski T, Lynch HT, Randall SA, Neuhausen SL, Senter L, Friedman S,  Ainsworth P, Singer C, Foulkes WD, Narod SA, Sun P, Kotsopoulos J.  Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.  Breast Cancer Res Treat. 2015 Jun;151(2):435-41. doi: 10.1007/s10549-015-3393-4. PMID:  25935583. Epub 2015 May 3.
    2. Kotsopoulos J, Lubinski J, Neuhausen SL, Gronwald J, Lynch HT, Huzarski T, Demsky R, Foulkes WD, Senter L, Friedman S,  Ainsworth P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Weight gain after oophorectomy among women with a BRCA1 or BRCA2 mutation.  Womens Health (Lond Engl). 2015 Jul;11(4):453-9  DOI:  10.2217/WHE.15.4  PMID:  26258912
    3. Semple J, Metcalfe KA, Lubinski J, Huzarski T, Gronwald J, Armel S, Lynch HT, Karlan B, Foulkes W, Singer CF, Neuhausen SL, Eng C, Iqbal J, Narod SA, Hereditary Breast Cancer Clinical Study Group (incl. Ainsworth, P). Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers? Breast Cancer Res Treat, 2015 Nov 1; 154 (1): 163-9.   DOI: 10.1007/s10549-015-3596-8. PMID 26467043.
    4. Nikitina D, Chen Z, Vallis K, Poll A, Ainsworth P, Narod SA, Kotsopoulos J. Relationship between Caffeine and Levels of DNA Repair and Oxidative Stress in Women with and without a BRCA1 Mutation. J Nutrigenet Nutrigenomics, 2015 Jan 1; 8 (4-6): 174-84.  DOI: 10.1159/000439110. PMID 26670362.
    5. Alturkustani M, Mandzia J, Watling C, Cooper P, Bahakeen B, Leung A, Gulka I,  Howlett CHammond R.  CNPC: Acute myelopathy in a 68 year old male.  Can J Neurol Sci.  2015; 42: 466-471 DOI: 10.1017/cjn.2015.305
    6. Alturkustani M, Keith J, Hazrati LN, Rademakers R,  Ang LC.  Pathologic staging of white matter lesions in adult-onset leukoencephalopathy/leukodystrophy with axonal spheroids  J Neuropathol Exp Neurol. Top of Form2015 Mar;74(3):233-40  DOI:  10.1097/NEN.0000000000000168  PMID:  25668567
    7. Kertesz A, Finger E, Murrell J, Chertkow H,  Ang LC, Baker M, Ravenscroft T, Rademakers R, Muno, DG.  Progressive Supranuclear Palsy in a family with TDP-43 pathology.  Neurocase, Volume 21, Issue 2, 4 March 2015, Pages 178-184.  doi: 10.1080/13554794.2013.878729.
    8. Tong J,  Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ.  Low levels of astroglial markers in Parkinson's disease: relationship to α-synuclein accumulation.  Neurobiol Dis 2015 Jun 21;82:243-253  DOI:  10.1016/j.nbd.2015.06.010  PMID:  26102022
    9. Abuzgaia AM, Hardy DB,  Arany E. Regulation of postnatal pancreatic Pdx1 and downstream target genes after gestational exposure to protein restriction in rats. Reproduction (2015) 149 293–303. DOI: 10.1530/REP-14-0245 ISSN 1470–1626 (paper) 1741–7899 (online).
    10. Asfaha S, Hayakawa Y, Muley A, Stokes S, Graham, TA, Ericksen RE, Westphalen CB, vonBurstin J, Mastracci TL, Worthley DL, Guha C, Quante M, Rustgi AK, Wang TC.  Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine.  J.Stem Volume 16, Issue 6, 4 June 2015, Pages 627-638  DOI:  10.1016/j.stem.2015.04.013.
    11. Tsimbiri, P.F., Moturi, W.N., Sawe, J., Henley, P. and  Bend, J.R. Health impact of pesticides on residents and horticultural workers in the Lake Naivasha Region, Kenya. Occupational Diseases and Environmental Medicine. 3: 24-34, 2015.  http://dx.doi.org/10.4236/odem.2015.32004
    12. Jeurissen S,  Bend JR. Aliphatic and Alicyclic Hydrocarbons (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 169-193.
    13. Williams GM,  Bend JR. Monocyclic and Bicyclic Secondary Alcohols, Ketones and Related Esters (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 263-276.
    14. Jeurissen S.  Bend JR. Phenyl-Substituted Aliphatic Alcohols and Related Aldehydes and Esters (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 297-315.
    15. Williams GM,  Bend JR. Miscellaneous Nitrogen-Containing Substances (addendum) (First draft). In WHO FOOD ADDITIVES SERIES: 70: Safety evaluation of certain food additives and contaminants.  International Programme on Chemical Safety, World Health Organization, Geneva, 2015, 241-261.
    16. Tsimbiri PF, Moturi WN, Sawe J, Henley P,  Bend JR. Health impact of pesticides on residents and horticultural workers in the Lake Naivasha Region, Kenya. ODEM. 3: 24-34, 2015. DOI:  10.4236/odem.2015.32004
    17. Bend JR, Xia XY, Chen DF, Awaysheh A, Lo A, Rieder MJ, Rylett  RJ. Attenuation of oxidative stress in HEK 293 cells by the TCM constituents schisanhenol, baicalein, resveratrol or crocetin and two defined mixtures. J Pharm Pharm Sci. 18: 661-682, 2015
    18. Zhang L, Chen DF, Xia XY, Yip C, Rieder MJ,  Bend JR. Potential complementary therapy for adverse drug reactions to sulfonamides: Chemoprotection against oxidative and nitrosative stress by TCM constituents and defined mixtures J Pharm Pharm Sci. 18: 528-546, 2015
    19. Balint B, Yin H, Chakrabarti S, Chu M, Sims S, Pickering JG. Collectivization of vascular smooth muscle cells via TGF-ß - cadherin-11-dependent adhesive switching. Arterioscler Thromb Vasc Biol. 2015 Mar 12. pii: ATVBAHA.115.305310.
    20. Chakrabarti S. Unacylated Ghrelin: a gut-limb connection (Invited commentary). Diabetes. 2015 Apr;64(4):1097-8. doi: 10.2337/db14-1825. PMID: 25805761
    21. Frontini M, Yin H,  Nong Z, O’Neil C,  Arpino JM , Xu Y, Balint B, Ward A, Chakrabarti S, Ellis C, Gros R, Pickering JG. Normalization of Tumor Microvessels and Suppression of Metastasis by Fibroblast Growth Factor 9. Journal of biological Chemistry 2015 Jul 16. pii: jbc.M115.652222.
    22. Iordanous Y, Belrose JC, Cadieux Dc, Chakrabarti S, Farmer JP, Allen LH. P63 positive mucoepidermoid Tumor of the Lacrimal Sac with Associated Papilloma. Orbit. 2015;34(4):220-2. doi: 10.3109/01676830.2015.1049370. Epub 2015 Jun 29. PMID: 26121166
    23. Mortuza R, Feng B, Chakrabarti S. SIRT1 Reduction Causes Renal and Retinal injury in Diabetes through Endothelin 1 (ET-1) and Transforming Growth Factor β1 (TGF-β1). J Cell Mol Med. 2015 Aug;19(8):1857-67. doi: 10.1111/jcmm.12557. Epub 2015 Mar 6. PMID: 25753689
    24. Puthanveetil P, Chen S, Feng B, Gautam A, Chakrabarti S. Long non coding RNA MALAT1 regulates glucose induced inflammatory mediator induction in the endothelial cells. J Cell Mol Med. DOI: 10.1111/jcmm.12576
    25. Ruiz M, Feng B, Chakrabarti S. Polycomb Repressive Complex 2 regulates miR-200b in retinal endothelial cells: potential relevance in diabetic retinopathy. PLoS One. 2015 Apr 17;10(4):e0123987. doi: 10.1371/journal.pone.0123987. eCollection 2015. PMID: 25884496
    26. Wu Y, Chakrabarti S. ERK5 mediated signaling in Diabetic Retinopathy. Med Hypothesis Discov Innov Ophthalmol. 2015 Spring;4(1):17-26. PMID: 25861671
    27. Cecchini MJ, Ishak CA, Passos DT, Warner A, Palma DA,  Howlett CJDriman DK, Dick FA.  Loss of the retinoblastoma tumor suppressor correlates with improved outcome in patients with lung adenocarcinoma treated with surgery and chemotherapy.  Hum Pathol. 2015 Dec;46(12):1922-34. DOI: 10.1016/j.humpath.2015.08.010. PMID:  26475095
    28. Cecchini MJ, Yu E, Potvin K, D'Souza, D, Lock MM.  Concurrent or Sequential Hormonal and Radiation Therapy in Breast Cancer: A LiteratureReview.  Cureus 7(10): e364. 2015 10 DOI:10.7759/cureus.364 
    29. Daley T, Dunn G,  Darling MR. Central xanthoma of the jaws: A clinicopathologic entity?  Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Volume 119, Issue 1, 1 January 2015, Pages 92-100 DOI: 10.1016/j.oooo.2014.09.018.
    30. Delport JA, Peters G, Diagre D,  Lannigan RJohn MA. Identification of Coagulase-Negative Staphylococci by the Bruker MALDI-TOF BioTyper Campared to the VITEK 2 and MIS Gas Liquid Chromatography. J Bacteriol Mycol Open Access, 2015 Jun: 1(1): 00003.  DOI: 10.15406/jbmoa.2015.01.00003
    31. Al-Judaibi B,  Driman DK, Chandok N.  An elderly lady with significant weight loss.  Arab J Gastroenterol. 2015 Mar 14. pii: S1687-1979(14)00075-6. [Epub ahead of print]   DOI:  10.1016/j.ajg.2014.10.003  PMID:  25784461.
    32. O'Connor K, Li-Chang HH, Kalloger SE, Peixoto RD, Webber DL, Owen DA,  Driman DK, Kirsch R, Serra S, Scudamore CH, Renouf DJ, Schaeffer DF.  Tumor budding is an independent adverse prognostic factor in pancreatic ductal adenocarcinoma  Am J Surg Pathol. 2015 Apr;39(4):472-8  DOI:  10.1097/PAS.0000000000000333  PMID: 25634751.
    33. Wells M,  Driman DK, Al-Judaibi B.  A treatable mimicker of cholangiocarcinoma.  Can J Gastroenterol Hepatol. 2015 Aug-Sep;29(6):291-2.  PMID:  26361640
    34. Hashi AA, Delport JA, Elsayed S, Silverman MS. Staphylococcus pettenkoferi bacteremia: A case report and review of the literature. Can J Infect Dis Med Microbiol. 2015 Nov-Dec;26(6):319-22. DOI: 10.1155/2015/748154 PMID: 26744589
    35. Mrkobrada M, Ying I, Mokrycke S, Dresser G, Elsayed S, Bathini V, Boyce E, Luke P. CUA Guidelines on antibiotic prophylaxis for urologic procedures. Can Urol Assoc J. 2015 Jan-Feb;9(1-2):13-22. doi: 10.5489/cuaj.2382. PMID: 25737749
    36. Vilos, GA, Oraif, A, Vilos, AG,  Ettler, H, Edris, F, Abu-Rafea, B.  Long-term clinical outcomes following resectoscopic endometrial ablation of non-atypical endometrial hyperplasia in women with abnormal uterine bleeding.  Journal of Minimally Invasive Gynecology, Volume 22, Issue 1, 1 January 2015, Pages 66-77.  DOI: 10.1016/j.jmig.2014.07.009  PMID: 25749467.
    37. Samaan S, Khella HWZ, Girgis A, Scorilas A, Lianidou E,  Gabril M, Krylov SN, Jewett M, Bjarnason GA, El-Said H, Yousef GM.  MiR-210 is a prognostic marker in clear cell renal cell carcinoma   Journal of Molecular Diagnostics , 17 ( 2 ) pp. 136 - 144 DOI:  10.1016/j.jmoldx.2014.10.005  PMID:  25555365.
    38. Karamchandani JR,  Gabril MY, Ibrahim R, Scorilas A, Filter E, Finelli A, Lee JY, Ordon M, Pasic M, Romaschin AD, Yousef GM.  Profilin-1 expression is associated with high grade and stage and decreased disease-free survival in renal cell carcinoma  Hum Pathol 2015 May;46(5):673-80 DOI:  10.1016/j.humpath.2014.11.007  PMID:  25704627
    39. Gabril M, Girgis H, Scorilas A, Rotondo F, Wala S, Bjarnason GA, Ding Q, Evans A, Tawedrous E, Pasic M, Finelli A, Al-Haddad S, Yousef GM.  S100A11 is a potential prognostic marker for clear cell renal cell carcinoma.  Clin Exp Metastasis. 2015 Oct 15. [Epub ahead of print]  PMID:  26472670
    40. White-Al Habeeb NM, Di Meo A, Scorilas A, Rotondo F, Masui O, Seivwright A,  Gabril M, Girgis AHA, Jewett MA, Yousef GM.  Alpha-enolase is a potential prognostic marker in clear cell renal cell carcinoma.  Clin Exp Metastasis. 2015 Aug;32(6):531-41  DOI:  10.1007/s10585-015-9725-2  PMID:  26037892
    41. Rizek P, Ikeda KM, Mele T,  Garcia B, Gofton TE.  Bowel Ischemia in Refractory Status Epilepticus: Report of Two Cases and Review of the Literature  Neurocrit Care. 21 July 2015, 4p  DOI:  10.1007/s12028-015-0181-2  PMID:  26195088  [Epub ahead of print]
    42. Zhang ZX, Huang X, Jiang J, Lau A, Yin Z, Liu W,  Haig A, Jevnikar AM.Top of Form Natural Killer Cells Mediate Long-term Kidney Allograft Injury  Transplantation 2015 May;99(5):916-24 DOI:  10.1097/TP.0000000000000665 PMID:  25719259
    43. Yan, Y, Zhang ZX, Lian D,  Haig A, Bhattacharjee RN, Jevnikar AM.  IL-37 inhibits IL-18-induced tubular epithelial cell expression of pro-inflammatory cytokines and renal ischemia-reperfusion injury  Kidney International  87 ( 2 ) pp. 396 – 408  DOI: 10.1038/ki.2014.295 PMID:  25207880
    44. Ismail OZ, Zhang X, Wei J,  Haig A, Denker BM, Suri RS, Sener A, Gunaratnam L.  Kidney injury molecule-1 protects against Gα12 activation and tissue damage in renal ischemia-reperfusion injury  Am J Pathol.  2015 May;185(5):1207-15  DOI:  10.1016/j.ajpath.2015.02.003  PMID:  25759266
    45. Czikk MJ, Totten S,  Hammond RR, Richardson BS.  MAP-2 and Synaptophysin in the Preterm and Near-term Ovine Fetal Brain and the effect of Intermittent Umbilical Cord Occlusion.  Reprod Sci. 2015, Vol. 22(3) 367-37, epub 2014 Apr 3. DOI: 10.1177/1933719114529371. PMID: 24700051
    46. Goubran M, DeRibaupierre S,  Hammond RR, Currie C, Burneo JG, Parrent AG, Peters TM, Khan AR.Registration of in-vivo to ex-vivo MRI of surgically resected specimens: A pipeline for histology to in-vivo registration.  J Neurosci Methods. 2015 Feb 15;241:53-65 DOI: 10.1016/j.jneumeth.2014.12.005. Epub 2014 Dec 13.  PMID: 25514760
    47. Goubran M,  Hammond RR, de Ribaupierre S, Burneo JG, Mirsattari S, Steven DA,  Parrent AG,  Peters TM,.Khan AR.  Magnetic resonance imaging and histology correlation in the neocortex in temporal lobe epilepsy.  Ann Neurol. 2015 Feb;77(2):237-50. DOI: 10.1002/ana.24318. Epub 2014 Dec 17  PMID: 25514760  (Cover Article)
    48. Pasarikovski C,  Allevato P,  Hammond RR, Elashaal A.  Pilocytic astrocytoma of the lower thoracic spine in an adult patient.  Acta Neurochir (Wien). 2015 Jul;157(7):1179-81  DOI: 10.1007/s00701-015-2458-9. Epub 2015 May 31.  PMID: 26024949
    49. Torchia J, Picard D, Lafay-Cousin L, Hawkins CE, Kim SK, Letourneau L, Ra YS, Ho KC, Chan TS, Sin-Chan P, Dunham CP, Yip S, Ng HK, Lu JQ, Albrecht S, Pimentel J, Chan JA, Somers GR, Zielenska M, Faria CC, Roque L, Baskin B, Birks D, Foreman N, Strother D, Klekner A, Garami M, Hauser P, Hortobágyi T, Bognár L, Wilson B, Hukin J, Carret AS, Van Meter TE, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheineman K, Johnston D, Michaud J, Zelcer S,  Hammond RRamsay DA, Fleming AJ, Lulla RR, Fangusaro JR, Sirachainan N, Larbcharoensub N, Hongeng S, Barakzai MA, Montpetit A, Stephens D, Grundy RG, Schüller U, Nicolaides T, Tihan T, Phillips J, Taylor MD, Rutka JT, Dirks P, Bader GD, Warmuth-Metz M, Rutkowski S, Pietsch T, Judkins AR, Jabado N, Bouffet E, Huang A.  Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.  Lancet Oncol. 2015 May;16(5):569-82.  DOI: 10.1016/S1470-2045(15)70114-2. Epub 2015 Apr 14. PMID:  25882982
    50. Xu A, Matushewski B, Cao M,  Hammond R, Frasch MG, Richardson BS.  The Ovine Fetal and Placental Inflammatory Response to Umbilical Cord Occlusions With Worsening Acidosis.  Reprod Sci. 2015 Apr 15. pii: 1933719115580994. [Epub ahead of print]  PMID:  25878209
    51. Zeineh MM, Chen Y, Kitzler HH,  Hammond R, Vogel H, Rutt BK.  Activated iron-containing microglia in the human hippocampus identified by magnetic resonance imaging in Alzheimer disease.   Neurobiol Aging. 2015 Sep;36(9):2483-500. DOI:10.1016/j.neurobiolaging.2015.05.022. Epub 2015 Jun 6.  PMID:  26190634
    52. Magaki S, Chang E,  Hammond RR, Yang I, Mackenzie IR, Chou BT, Choi SI, Jen JC, Pope WB, Bell DA, Vinters HV. Two cases of rheumatoid meningitis. Neuropathology. 2015 Sep 8. DOI: 10.1111/neup.12238. [Epub ahead of print]  PMID: 26350538.
    53. Ikeda KM, Das S, Strong M, Mirsattari SM, Leung A, Steven D,  Hammond R.  Diagnosis of Inclusion Can J Neurol Sci. 2015; 24: 138-143
    54. Taylor G, Gravel D, Saxinger L, Bush K, Simmonds K, Matlow A, Embree J, Le Saux NL, Johnston L, Suh KN, Embil J, Henderson E,  John M, Roth V, Wong A, Bryce E, Dow G, Gardam M, Hutchinson J, Kibsey P, Langley J, Loeb M, McGeer A, Michaud S, Miller M, Moore D, Mulvey M, Ofner M, Paton S, Stegenga J, Weiss K, Zoutman D.  Prevalence of antimicrobial use in a network of Canadian hospitals in 2002 and 2009.  Can J Infect Dis Med Microbiol March/April 2015, Volume 26 Issue 2: 85- 89
    55. Schick BA, Tobe JS,  Joseph MG, Rouse TB,  Gabril MY.   Incidental Merkel Cell Carcinoma in a Cutaneous Horn: A Case Report. Dermatol Pract Concept. 2015 Jan; 5(1): 47–50. Published online 2015 Jan 30. DOI:  10.5826/dpc.0501a08  PMCID: PMC4325691
    56. Joseph MG, Shibani A, Panjwani N, Arab A,  Shepherd J, Stitt W,  Inculet R.  Usefulness of Ki-67, Mitoses, and Tumor Size for Predicting Metastasis in Carcinoid Tumors of the Lung: A Study of 48 Cases at a Tertiary Care Centre in Canada. Lung cancer international Volume 2015, Article ID 545601, 7 pages DOI:  10.1155/2015/545601
    57. Kum JY,  Khan  ZA   Mechanisms of propranolol action in infantile hemangioma.  Dermato-Endocrinology, 6:1, e979699  DOI:  10.4161/19381980.2014.979699
    58. Dorman SN, Baranova K,  Knoll JH, Urquhart BL, Mariani G, Carcangiu ML, Rogan PK.  Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning.  Mol Oncol. 2015 Aug 22. pii: S1574-7891(15)00146-5   [Epub ahead of print]  DOI:  10.1016/j.molonc.2015.07.006  PMID:  26372358
    59. Khan WA, Rogan PK,  Knoll JH.  Reversing chromatin accessibility differences that distinguish homologous mitotic metaphase chromosomes.  Mol Cytogenet. 2015 Aug 13;8:65  DOI:  10.1186/s13039-015-0159-y  PMID:  26273322
    60. Lerner-Ellis J, Wang M, White S, Lebo MS; Knoll J and Canadian Open Genetics Repository Group. 

      Canadian Open Genetics Repository (COGR): a unified clinical genomics database as a community resource for standardizing and sharing genetic interpretations. 

      J Med Genet. 2015 Jul;52(7):438-45. doi: 10.1136/jmedgenet-2014-102933. Epub 2015 Apr 22. PMID: 25904639

    61. Parsons P, Sedig K, Mercer RE, Khordad M, Knoll J, Rogan P. Visual Analytics for supporting evidence-based interpretation of molecular cytogenomic findings (conference paper). ACM International Conference Proceeding Series Volume 25-October-2015, 25 October 2015, Article number 2. 2015 Workshop on Visual Analytics in Healthcare, VAHC 2015; Chicago; United States; 25 October 2015; Code 119172
    62. Theurer JA, Stecho W, Yoo J,  Kwan KWehrli B, Harry V, Black M, Pinto N, Winquist E, Palma D, Richter S, Barrett JW, Danielle MacNeil S, Fung K,  Howlett CJ, Nichols AC.  Feasibility of Targeting PIK3CA Mutations in Head and Neck Squamous Cell Carcinoma.  Pathol Oncol Res. 2015 Aug 14. [Epub ahead of print]  PMID:  26271341
    63. Owrangi AM,  Lannigan R, Simonovic SP.  Mapping climate change-caused health risk for integrated city resilience modeling.  Nat Hazards  6 January 2015, 22p  doi: 10.1007/s11069-014-1582-9.
    64. Habib E, Linher-Melville K, Lin HX, and Singh G. Expression of xCT and activity of system xc− are regulated by NRF2 in human breast cancer cells in response to oxidative stress. Redox Biology, 2015, 5: 33-42. DOI: 10.1016/j.redox.2015.03.003  PMID: 25827424
    65. Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G,  Sadikovic B. Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia. Eur J Haematol. 2015 Jun 8.  DOI: 10.1111/ejh.12597. [Epub ahead of print]  PMID:26059983 
    66. Decker KM,  McLachlin CM, Lotocki R; Pan-Canadian Cervical Cancer Screening Network Monitoring Program Performance Working Group.  Performance measures related to colposcopy for canadian cervical cancer screening programs: identifying areas for improvement. J Obstet Gynaecol Can. 2015 Mar;37(3):245-51.  PMID:  26001871
    67. Hemmett J, Qirjazi E, Weir MA,  Moussa M, Landry YD, Gunaratnam L.  Cardiac, renal, and central nervous system dysfunction with eosinophilia: Eosinophilic granulomatosis with polyangiitis.  Lancet 2015 Jan 31;385(9966):480  DOI:  10.1016/S0140-6736(14)62352-7  PMID:  25706976.
    68. Imani F, Ramezani M, Nouranian S, Gibson E, Khojaste A, Gaed M,  Moussa M, Gomez JA, Romagnoli C, Leveridge M, Chang S, Fenster A, Siemens DR, Ward AD, Mousavi P, Abolmaesumi P  Ultrasound-Based Characterization of Prostate Cancer Using Joint Independent Component Analysis.  IEEE Trans Biomed Eng. 2015 Jul;62(7):1796-804 DOI:  10.1109/TBME.2015.2404300  PMID:  25720016
    69. Sy K,  Parfitt J, Marginean C, Riddell RH, Streutker CJ.  Inflammatory pseudotumours of the oesophagus - histological and immunohistochemical findings. Histopathology 2015 Jun;66(7):1003-9  doi:  10.1111/his.12615  PMID:  25393329
    70. Torchia J, Picard D, Lafay-Cousin L, Hawkins CE, Kim S-K, Letourneau L, Ra Y-S, Ho KC, Chan TSY, Sin-Chan P, Dunham CP, Yip S, Ng H-K, Lu J-Q, Albrecht S, Pimentel J, Chan JA, Somers GR, Zielenska M, Faria CC, Roque L, Baskin B, Birks D, Foreman N, Strother D, Klekner A, Garami M, Hauser P, Hortobágyi T, Bognár L, Wilson B, Hukin J, Carret A-S, Van Meter TE, Nakamura H, Toledano H, Fried I, Fults D, Wataya T, Fryer C, Eisenstat DD, Scheineman K, Johnston D, Michaud J, Zelcer S, Hammond R,  Ramsay DA, Fleming AJ, Lulla RR, Fangusaro JR, Sirachainan N, Larbcharoensub N, Hongeng S, Barakzai MA, Montpetit A, Stephens D, Grundy RG, Schüller U, Nicolaides T, Tihan T, Phillips J, Taylor MD, Rutka JT, Dirks P, Bader GD, Warmuth-Metz M, Rutkowski S, Pietsch T, Judkins AR, Jabado N, Bouffet E, Huang A.  Molecular subgroups of atypical teratoid rhabdoid tumours in children: An integrated genomic and clinicopathological analysis.  The Lancet Oncology  Volume 16, No. 5, p569–582, May 2015  DOI:  10.1016/S1470-2045(15)70114-2 
    71. Alahmadi M, Chin-Yee IH, Gupta K,  Rizkalla K, Hsia CC.  Leishmaniasis involving the bone marrow of a patient with multiple myeloma  Ann Hematol. 2015 Aug;94(8):1417-8  DOI:  10.1007/s00277-015-2376-1  PMID: Top of Form25876738
    72. Shapiro R,  Rizkalla K, Lam S.  Extensive Bone Marrow Necrosis in a Case of Acute Myeloid Leukemia Transformed from a Myeloproliferative Neoplasm  Case Rep Oncol Vol. 8, No. 2, 2015  DOI:  10.1159/000438822
    73. Tao A, Song J, Lan T, Xu X, Kvietys P, Kao R, Martin C,  Rui T.  Cardiomyocyte-fibroblast interaction contributes to diabetic cardiomyopathy in mice: Role of HMGB1/TLR4/IL-33 axis.  Biochim Biophys Acta. 2015 Oct;1852(10 Pt A):2075-85.  DOI:  10.1016/j.bbadis.2015.07.015  PMID:  26209013
    74. Farhan SMK, Wang J, Robinson JF, Prasad AN,  Rupar CA, Siu VM, Hegele RA.  Old gene, new phenotype: Mutations in heparan sulfate synthesis enzyme, EXT2 leads to seizure and developmental disorder, no exostoses  J Med Genet [Article in press]  DOI: 10.1136/jmedgenet-2015-103279
    75. Gannavarapu S, Prasad C, DiRaimo J, Napier M, Goobie S, Potter M, Chakraborty P, Karaceper M, Munoz T, Schulze A, MacKenzie J, Li L, Geraghty MT, Al-Dirbashi OY,  Rupar  CA.  Biotinidase deficiency: Spectrum of molecular, enzymatic and clinical information from newborn screening Ontario, Canada (2007-2014)  Mol Genet Metab. 2015 Aug 31. pii: S1096-7192(15)30044-5  DOI:  10.1016/j.ymgme.2015.08.010. [Epub ahead of print]  PMID:  26361991
    76. Lanktree MB, Lanktree BB, Paré G, Waye JS,  Sadikovic B, Crowther MA.  Examining the clinical use of hemochromatosis genetic testing. Canadian Journal of Gastroenterology and Hepatology.  Volume 29, Issue 1, 1 January 2015, Pages 41-45.  PMID25706573
    77. Lanktree MB, Sadikovic B, Crowther MA (2015) A 42-year-old man with elevated ferritin. CMAJ 187: 820-821. DOI: 10.1503/cmaj.140259  PMID: 25288314
    78. Zeesman S, Mccready E,  Sadikovic B, Nowaczyk MJ.  Prader-Willi syndrome and Tay-Sachs disease in association with mixed maternal uniparental isodisomy and heterodisomy 15 in a girl who also had isochromosome Xq.  American Journal of Medical Genetics, Part A.  Volume 167, Issue 1, 1 January 2015, Pages 180-184.  DOI: 10.1002/ajmg.a.36790.
    79. Boycott K, Hartley T, Adam S, Bernier F, Chong K, Fernandez BA, Friedman JM, Geraghty MT, Hume S, Knoppers BM, Laberge AM, Majewski J, Mendoza-Londono R, Meyn MS, Michaud JL, Nelson TN, Richer J,  Sadikovic B, Skidmore DL, Stockley T, Taylor S, van Karnebeek C, Zawati MH, Lauzon J, Armour CM; Canadian College of Medical Geneticists.  The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position Statement of the Canadian College of Medical Geneticists. J Med GenetTop of Form 2015 Jul;52(7):431-7  DOI:  10.1136/jmedgenet-2015-103144  PMID:  25951830
    80. Lerner-Ellis J, Wang M, White S, Lebo MS; Canadian Open Genetics Repository Group (incl  Sadikovic, B). The clinical application of genome-wide sequencing for monogenic diseases in Canada: Position statement of the Canadian College of medical geneticists.  J Med Genet. 52 ( 7 ) pp. 438 – 445  DOI:  10.1136/jmedgenet-2014-102933  PMID:  25904639
    81. Sangle NA, Taylor SL, Emond MJ, Depot M, Overholt BF, Bronner MP.  Overdiagnosis of high-grade dysplasia in Barrett’s esophagus: a multicenter, international study.  Modern Pathology (2015) 28, 758–765  DOI:  10.1038/modpathol.2015.2
    82. Agarwal AM, Liew Ma, Nussenzveig RH,  Sangle N, Heikal N, Yaish H, Christensen R.  Improved harmonization of eosin-5-maleimide binding test across different instruments and age groups.  Cytometry B Clin Cytom. 2015 Sep 18 [Epub ahead of print]  DOI:  10.1002/cyto.b.21326  PMID:  2638460
    83. Schick BA, McLean CA, Driman DK.  Negative colorectal polyp biopsies: the utility of cutting deeper levels. Virchows Arch. 2015 Oct 16. [Epub ahead of print]  PMID:  26475150
    84. Rakovitch E, Nofech-Mozes S, Hanna W, Baehner FL, Saskin R, Butler SM,  Tuck A, Sengupta S, Elavathil S,  Jani PA, Bonin M, Chang MC, Robertson SJ, Slodkowska E, Fong C, Anderson JM, Jamshidian F,  Miller DP, Cherbavaz DB,  Shak S, Paszat L.  A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by beast-conserving surgery alone  Breast Cancer Res Treat. 2015; 152(2): 389–398.  DOI:  10.1007/s10549-015-3464-6  PMID:  4491104
    85. Anborgh P, Caria LBR, Chambers AF,  Tuck AB, Stitt LW,  Brackstone M  Role of plasma osteopontin as a biomarker in locally advanced breast cancer  Am J Transl Res  2015; 7(4): 723–732  PMID:  26064440
    86. Klein J, Kong I, Paszat L, Nofech-Mozes S, Hanna W, Thiruchelvam D, Narod SA, Saskin R, Done SJ, Miller N, Youngson B,  Tuck A, Sengupta S, Elavathil L, Jani PA, Slodkowska E, Bonin M, Rakovitch E.  Close or positive resection margins are not associated with an increased risk of chest wall recurrence in women with DCIS treated by mastectomy: a population-based analysis  Springerplus. 2015 Jul 10;4:335  DOI:  10.1186/s40064-015-1032-5  PMID:  26185737
    87. Sultan A, Goela A,  Tweedie E, Awan K, Lavi S.  Multimodality Imaging for Assessment of Coronary Embolus.  Can J Cardiol. Volume 31, Issue 3, 1 March 2015, Pages 364.e5-364.e7 DOI:  10.1016/j.cjca.2014.12.010  PMID:  25746026
    88. Sarr O, Blake A, Thompson J, Zhao L, Rabicki K, Walsh JC, Welch I, Regnault TR. The differential effects of low birth weight and western diet consumption upon early life hepatic fibrosis development in guinea pig. J Physiol 2015 Dec 10 DOI: 10.1113/JP271777. [Epub ahead of print] PMID: 26662996
    89. Zhang Q, Pocrnich C, Kurian A, Hahn AF, Howlett C, Shepherd J, Rizkalla K. Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: a clinicopathologic study of 5 cases. Pathol Res Pract 2015 Sep 5. [epub ahead of print] DOI: 10.1016/j.prp.2015.08.007 PMID: 26847730
    90. Maleki Vareki S, Chen D, Di Cresce C, Ferguson PJ, Figueredo R, Pampillo M, Rytelewski M, Vincent M, Min W, Zheng X, Koropatnick. IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells.  PLoS One. 2015 Nov 18; 10(11):e0143435.  doi: 10.1371/journal.pone.0143435. eCollection 2015. PMID: 26579709

2014 Publications

    1. Phelan CM, Iqbal J, Lynch HT, Lubinski J, Gronwald J, Moller P, Ghadirian P, Foulkes WD, Armel S, Eisen A, Neuhausen SL, Senter L, Singer CF, Ainsworth P, Kim-Sing C, Tung N, Llacuachaqui M, Chornokur G, Ping S, Narod SA, Hereditary Breast Cancer Study Group. Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study. Br J Cancer. 2014 Jan 21;110(2):530-4.530-4 doi:10.1038/bjc.2013.741. PMID24292448
    2. Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, Eisen A, Gilchrist D, Blum JL, Zakalik D, Pal T, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group ( Ainsworth P, et al). Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Res Treat579-86 doi:10.1007/s10549-013-2. PMID24458845
    3. Finch AP, Lubinski J, Møller P, Singer CF, Karlan B, Senter L, Rosen B, Maehle L, Ghadirian P, Cybulski C, Huzarski T, Eisen A, Foulkes WD, Kim-Sing C, Ainsworth P, Tung N, Lynch HT, Neuhausen S, Metcalfe KA, Thompson I, Murphy J, Sun P, Narod SA. Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation. J Clin Oncol1547-53 doi:10.1200/JCO.2013.53.  PMID24567435
    4. Kertesz A, Finger E, Murrell J, Chertkow H, Ang LC, Baker M, Ravenscroft T, Rademakers R, Munoz DG. Progressive Supranuclear Palsy in a family with TDP-43 pathology. Neurocase doi:10.1080/13554794.201. PMID24479957
    5. Tong J, Fitzmaurice P, Furukawa Y, Schmunk GA, Wickham DJ, Ang LC, Sherwin A, McCluskey T, Boileau I, Kish SJ. Is brain gliosis a characteristic of chronic methamphetamine use in the human? Neurobiol Dis 107-18 doi:10.1016/j.nbd.2014.0. PMID24704312
    6. Lin AW, Das S, Fraser JA, Ang LC, Florendo-Cumbermack A, Jenkins ME, Tay KY. Emergence of Primary CNS Lymphoma in a Patient with Findings of CLIPPERS. Can J Neurol Sci. 2014 Jul;41(4):528-9.528-9.  PMID24878484
    7. Henley P, Lowthers M, Koren G, Fedha PT, Russell E, VanUum S, Arya S, Darnell R, Creed IF, Trick CG, Bend JR. Cultural and socio-economic conditions as factors contributing to chronic stress in sub-Saharan African communities. Can J Physiol Pharmacol. 92:725-32, 2014.
    8. Xiao J, Li J, Cai L, Chakrabarti S, Li X. Cytokines and diabetes research. Journal of Diabetes Research, Volume 2014, 2014, Article number 920613 PMID24551859
    9. Mortuza R, Chakrabarti S. Glucose-induced cell signaling in the pathogenesis of diabetic cardiomyopathy. Heart Fail Rev, 75-86 doi:10.1007/s10741-013-9. PMID23430126
    10. Chen S, Puthanveetil P, Feng B, Matkovich SJ, Dorn GW, Chakrabarti S. Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes. Journal of Cellular and Molecular MedicineVolume 18, Issue 3, March 2014, Pages 415-421. PMID24428157
    11. Feng B, Cao Y, Chen S, Ruiz M, Chakrabarti S. miRNA-1 regulates endothelin-1 in diabetes. Life Sci2014 Mar 7;98(1):18-23, doi:10.1016/j.lfs.2013.12.199. Epub 2014 Jan 3.  PMID24394957
    12. Cong W, Zhao T, Zhu Z, Huang B, Ma W, Wang Y, Tan Y, Chakrabarti S, Li X, Jin L, Cai L. Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase. J Nutr Biochem 463-74, doi:10.1016/j.jnutbio.20. PMID24629910
    13. Beaton MD, Chakrabarti S, Adams PC. Inflammation is not the cause of an elevated serum ferritin in non-alcoholic fatty liver disease. Ann Hepatol353-6. PMID24756010
    14. Mortuza R, Feng B, Chakrabarti S. miR-195 regulates SIRT1-mediated changes in diabetic retinopathy. Diabetologia1037-46, doi:10.1007/s00125-014-3. PMID24570140.
    15. Zhao YZ, Tian XQ, Zhang M, Cai L, Ru A, Shen XT, Jiang X, Jin RR, Zheng L, Hawkins K, Chakrabarti S, Li XK, Lin Q, Yu WZ, Ge S, Lu CT, Wong HL. Functional and pathological improvements of the hearts in diabetes model by the combined therapy of bFGF-loaded nanoparticles with ultrasound-targeted microbubble destruction. J Control Release. 2014 Jul 28;186:22-31. doi:10.1016/j.jconrel.2014.04.054. Epub 2014 May 9. PMID24815422.
    16. Cao Y, Feng B, Chen S, Chu Y, Chakrabarti S. Mechanisms of endothelial to mesenchymal transition in the retina in diabetes. Investigative Ophthalmology Visual ScienceInvest Ophthalmol Vis Sci. 2014 Oct 21;55(11):7321-31. doi:10.1167/iovs.14-15167. PMID25335984.
    17. Zuo Y, Wu Y, Wehrli B, Chakrabarti S, Chakraborty C. Modulation of ERK5 Is a novel mechanism by which CDc42 Regulates Migration of Breast Cancer Cells. Journal Cell Biochemistry. doi:10.1002/jcb.24950. 
    18. Zeng C, Zhong P, Zhao Y, Kanchana K, Zhang Y, Khan ZA, Chakrabarti S, Wu L, Wang J, Liang G. Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo. J Mol Cell Cardiol. 2015 ;79:1-12. Epub 2014 Oct 16
    19. Puthanveetil P, Thomas AA, Chakrabarti S. microRNAs in diabetes - are they perpetrators in disguise or just epiphenomena? Non-coding RNAs in Endocrinology. Volume 1, Issue 1, ISSN (Online) 2300-4258. doi:10.2478/micrnado-2014-0002, September 2014.
    20. Beaucage KL, Xiao A, Pollmann SI, Grol MW, Holdsworth DW, Sims SM, Darling MR, Dixon SJ. Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice. Purinergic Signalling 2014 Jun;10(2):291-304. doi:10.1007/s11302-013-9388-x. Epub 2013 Nov 13.  PMID24222214.
    21. Poon R, Su N, Ching V, Darling M, Grushka M. Reduction in unstimulated salivary flow rate in burning mouth syndrome. Br Dent J. 2014 Oct 10;217(7):E14. doi:10.1038/sj.bdj.2014.884. PMID25303607.
    22. Wilson A,  Delport J, Ponich T. Candida glabrata esophagitis: Are we seeing the emergence of a new azole-resistant pathogen?  International Journal of Microbiology. 2014;2014:371631. doi: 10.1155/2014/371631. Epub 2014 Dec 3
    23. Delport JA, John MA, Conkey B, MacDonald K, Lannigan R. Comparison of Direct Identification of Bacteria from VersaTrek Blood Culture Bottles Using a Seven Present Saponin Extraction Method and SepsiTyper by the Bruker MALDI-TOF. Int J Infect Dis. 2014 Apr; 21 (S1): 371.  DOI:  10.1016/j.ijid.2014.03.1186
    24. Anantha RV, Jegatheswaran J, Pepe DL, Priestap F, Delport J, Haeryfar SM, McCormick JK, Mele T. Risk Factors for Mortality Among Canadian Patients with Staphylococcus aureus Bacteremia: A Single Centre Retrospective Cohort Study. CMAJ Open. 2014 Oct: 2(4): E352-359. DOI: 10.9778/ cmajo.20140018.  eCollection 2014 Oct.  PMID:25553328
    25. Stuart JI, Delport J, Lannigan R, Zahariadis G. Determination of real-time polymerase chain reaction uncertainty of measurement using replicate analysis and a graphical user interface with Fieller's theorem. Can J Infect Dis Med Microbiol. 2014 Jul;25(4):207-10. PMID: 25285125
    26. Castonguay MC, Li-Chang HH, Driman DK. Venous invasion in oesophageal adenocarcinoma: enhanced detection using elastic stain and association with adverse histological features and clinical outcomes. Histopathology 693-700, doi:10.1111/his.12308. PMID24117900.
    27. Osmond A, Li-Chang H, Kirsch R, Divaris D, Falck V, Liu DF, Marginean C, Newell K, Parfitt J, Rudrick B, Sapp H, Smith S, Walsh J, Wasty F, Driman DK. Interobserver variability in assessing dysplasia and architecture in colorectal adenomas: a multicentre Canadian study. J Clin Pathol, doi:10.1136/jclinpath-20. PMID25004943.
    28. Rajakumar C, Vilos GA, Vilos AG, Marks JL, Ettler HC, Pautler SS. Combined Transurethral and Laparoscopic Partial Cystectomy and Robotically Assisted Bladder Repair for the Treatment of Bladder Endocervicosis: Case Report and Review of the Literature. J Obstet Gynaecol Can141-145. PMID24518913.
    29. Toro CM, Janvier J, Zhang K, Fonseca K, Gregson D, Church D, Laupland K, Rabin H, Elsayed S, Conly J. Community-associated methicillin-resistant Staphylococcus aureus necrotizing pneumonia without evidence of antecedent viral upper respiratory infection. Can J Infect Dis Med Microbiol. 2014 May;25(3):e76-82. DOI: 10.1155/2014/952603 PMID: 25285117
    30. Girgis H, Masui O, White NM, Scorilas A, Rotondo F, Seivwright A, Gabril M, Filter ER, Girgis AH, Bjarnason GA, Jewett MA, Evans A, Al-Haddad S, Siu KM, Yousef GM. Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma. Mol Cancer101 doi:10.1186/1476-4598-13. PMID24885701.
    31. Canadian Association of Pathologists Telepathology Guidelines Committee, Bernard C, Chandrakanth SA, Cornell IS, Dalton J, Evans A, Garcia BM, Godin C, Godlewski M, Jansen GH, Kabani A, Louahlia S, Manning L, Maung R, Moore L, Philley J, Slatnik J, Srigley J, Thibault A, Picard DD, Cracower H, Tetu B. Guidelines from the Canadian Association of Pathologists for establishing a telepathology service for anatomic pathology using whole-slide imaging. J Pathol Inform15, doi:10.4103/2153-3539.129455. eCollection 2014. PMID24843826.
    32. Wang H, Zhang Z, Tian W, Liu T, Han H, Fu Q, Garcia B, Li X. Memory T Cells Mediate Cardiac Allograft Vasculopathy and are Inactivated by Anti-OX40L Monoclonal Antibody. Cardiovasc Drugs Ther.2014; 28: 115-22. doi:10.1007/s10557-013-6502-9. PMID24254032.
    33. Palmer TD, Martínez CH, Vasquez C, Hebron KE, Jones-Paris C, Arnold SA, Chan SM, Chalasani V, Gomez-Lemus JA, Williams AK, Chin JL, Giannico GA, Ketova T, Lewis JD, Zijlstra A. Integrin-free tetraspanin CD151 can inhibit tumor cell motility upon clustering and is a clinical indicator of prostate cancer progression. Cancer Res173-87 doi:10.1158/0008-5472.CA. PMID24220242.
    34. Lau A, Khan K, Pavlosky A, Yin Z, Huang X, Haig A, Liu W, Singh B, Zhang ZX, Jevnikar AM. Serine Protease Inhibitor-6 Inhibits Granzyme B-Mediated Injury of Renal Tubular Cells and Promotes Renal Allograft Survival. Transplantation doi:10.1097/TP.000000000. PMID24918613.
    35. Lau A, Wang S, Liu W, Haig A, Zhang ZX, Jevnikar AM. Glycyrrhizic Acid Ameliorates HMGB1-Mediated Cell Death and Inflammation after Renal Ischemia Reperfusion Injury. Am J Nephrol84-95 doi:10.1159/000364908. PMID25059568.
    36. Rizek P, Cheung C, McLachlan RS, Hayman-Abello B, Lee DH, Hammond RR, Mirsattari SM. Childhood-onset nonprogressive chronic encephalitis. Epilepsy Behav. 2014 Feb;31:85-90 doi:10.1016/j.yebeh.2013. PMID24368410.
    37. Piorkowska K, Thompson JA, Nygard K, Matushewski B, Hammond RR, Richardson BS.   Synaptic Development and Neuronal Myelination are Altered with Growth Restriction in Fetal Guinea Pigs, Dev Neurosci, 2014;36(6):465-76. DOI: 10.1159/000363696. Epub 2014 Sep 26  PMID: 25277216
    38. Haust, MD, Gilber-Barness EF.  Founders of Pediatric Pathology: Remembering Dr Marie Valdes-Dapena.  Pediatric and Developmental Pathology 17, 165-168, 2014 doi: 10.2350/14-02-1442-PB.1
    39. Weinreb I, Piscuoglio S, Martelotto LG, Waggott D, Ng CK, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, da Cruz Paula A, Marchio C, Sakr RA, Lim R, Thompson LD, Chiosea SI, Seethala RR, Skalova A, Stelow EB, Fonseca I, Assaad A, How C, Wang J, de Borja R, Chan-Seng-Yue M, Howlett CJ, Nichols AC, Wen YH, Katabi N, Buchner N, Mullen L, Kislinger T, Wouters BG, Liu FF, Norton L, McPherson JD, Rubin BP, Clarke BA, Weigelt B, Boutros PC, Reis-Filho JS. Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. Nat Genet. 2014 Nov;46(11):1166-9 doi:10.1038/ng.3096. PMID25240283.
    40. Wong H, Watt C, Elsayed S, John M, Johnson G, Katz K, Krajden S, Lee C, Mazzulli T, Ostrowska K, Richardson D, Toye B, Vermeiren C, Yamamura D, Simor AE. Characterization of methicillin-resistant Staphylococcus aureus isolates from patients with persistent or recurrent bacteremia. Can J Infect Dis Med Microbiol. 2014;25:83-6. DOI: 10.1155/2014/853482 PMID: 24855475
    41. Lutz K, Hayward V, Joseph M, Wong E, Temple-Oberle C. Current biopsy practices for suspected melanomas: A Survey of Family Physicians in Southwestern Ontario. The Canadian Journal of Plastic Surgery, 22(3), 175-178.
    42. Kum JJY, Khan ZA. Propranolol inhibits growth of hemangioma-initiating cells but does not induce apoptosis. Pediatr Res75: 381-388, 2014 doi:10.1038/pr.2013.231. Epub 2013 Dec 2. PMID24296797.
    43. Keats EC, Dominguez JM, Grant MB, Khan ZA. Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced adipogenesis. Stem Cells32: 1649–1660, 2014 doi: 10.1002/stem.1659.  PMID24496952.
    44. Piccinin MA, Khan ZA. Pathophysiological role of enhanced bone marrow adipogenesis in diabetic complications. Adipocyte 3; 14-23, 2014 doi:10.4161/adip.32215.
    45. Cutz JC1, Craddock KJ, Torlakovic E, Brandao G, Carter RF, Bigras G, Deschenes J, Izevbaye I, Xu Z, Greer W, Yatabe Y, Ionescu D, Karsan A, Jung S, Fraser RS, Blumenkrantz M, Lavoie J, Fortin F, Bojarski A, Côté GB, van den Berghe JA, Rashid-Kolvear F, Trotter M, Sekhon HS, Albadine R, Tran-Thanh D, Gorska I, Knoll JH, Xu J, Blencowe B, Iafrate AJ, Hwang DM, Pintilie M, Gaspo R, Couture C, Tsao MS. Canadian Anaplastic Lymphoma Kinase Study: A Model for multicenter standardization and optimization of ALK testing in lung cancer. J Thoracic Oncology 9(9):1255-1263 doi:10.1097/JTO.0000000000000239  PMID25122422.
    46. Rogan PK, Li Y, Wickramasinghe A, Subasinghe A, Caminsky N, Khan W, Samarabandu J, Wilkins R, Flegal F, Knoll JH. Automating dicentric chromosome detection from cytogenetic biodosimetry data. Radiat Prot Dosimetry2014 Jun;159(1-4):95-104 doi:10.1093/rpd/ncu133. Epub 2014 Apr 21. PMID24757176.
    47. Khan WA, Rogan PK, Knoll JH

      Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes. 

      Mol Cytogenet. 2014 Nov 19;7(1):70. doi: 10.1186/s13039-014-0070-y. eCollection 2014. PMID: 25520753

    48. Owrangi AM, Lannigan R, Simonovic SP. Interaction between land-use change, flooding and human health in Metro Vancouver, Canada. Natural Hazards, Volume 72, Issue 2, June 2014, Pages 1219-1230
    49. Cancer Genome Atlas Research Network (affiliated with Ontario Tumour Bank: Bartlett JMS, Kodeeswara S, Parfitt J, Sekhon H, Albert M). Comprehensive molecular profiling of lung adenocarcinoma. Nature543-50 doi:10.1038/nature13385. PMID25079552.
    50. Sy K, Parfitt J, Marginean C, Riddell RH, Streutker CJ. Inflammatory pseudotumours of the esophagus. Histopathology. 2014 Nov 13. doi:10.1111/his.12615. [Epub ahead of print]. PMID25393329.
    51. Farhan SM, Wang J, Robinson JF, Lahiry P, Siu VM, Prasad C, Kronick JB, Ramsay DA, Rupar CA, Hegele RA. Exome sequencing identifies NFS1 deficiency in a novel Fe-S cluster disease, infantile mitochondrial complex II/III deficiency. Mol Genet Genomic Med 73-80 doi:10.1002/mgg3.46. PMID24498631.
    52. Prasad M, Narayan B, Prasad AN, Rupar CA, Levin S, Kronick J, Ramsay D, Tay KY, Prasad C. MELAS: A Multigenerational Impact of the MTTL1 A3243G MELAS Mutation. Can J Neurol Sci. 2014 Mar;41(2):210-9. PMID24534033.
    53. Cohen MC, Ramsay DA. "Shaken baby syndrome" and forensic pathology. Forensic Sci Med Pathol244-5 doi:10.1007/s12024-013-9. PMID24464795.
    54. Bell K, Hodgson N, Levine M, Sadikovic B, Zbuk K (2014) Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer. Breast Cancer Res Treat 146: 447-450 DOI: 10.1007/s10549-014-3011-x PMID: 24916180
    55. Cervigne NK, Machado J, Goswami RS, Sadikovic B, Bradley G, Perez-Ordonez B, Galloni NN, Gilbert R, Gullane P, Irish JC, Jurisica I, Reis PP, Kamel-Reid S (2014) Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis? Hum Mol Genet 23: 2618-2628. DOI: 10.1093/hmg/ddt657  PMID: 24403051
    56. Mahadevan S, Wen S, Wan YW, Peng HH, Otta S, Liu Z, Iacovino M, Mahen EM, Kyba M, Sadikovic B, Van den Veyver IB (2014) NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation. Hum Mol Genet 23: 706-716. DOI: 10.1093/hmg/ddt457  PMID: 24105472
    57. Sadikovic B, Pare G (2014) Genomics and epigenomics in pediatric oncology and clinical laboratory genetics. Clin Biochem 47: 731-732.  DOI: 10.1016/j.clinbiochem.2014.05.033 PMID: 24858242
    58. Sadikovic B, Fernandes P, Zhang VW, Ward PA, Miloslavskaya I, Rhead W, Rosenbaum R, Gin R, Roa B, Fang P (2014) Mutation Update for UBE3A variants in Angelman syndrome. Hum Mutat 35: 1407-1417.  DOI: 10.1002/humu.22687  PMID: 25212744
    59. Sangle NA, Schmidt RL, Patel JL, Jeffrey Medeiros L, Agarwal AM, Perkins SL, Salama ME. Optimized immunohistochemical panel to differentiate myeloid sarcoma from blastic plasmacytoid dendritic cell neoplasm. Mod Pathol.2014 Aug;27(8):1137-43. doi:10.1038/modpathol.2013.238. Epub 2014 Jan 3. PMID24390220.
    60. Layfield LJ, Schmidt RL, Sangle N, Crim JR. Diagnostic accuracy and clinical utility of biopsy in musculoskeletal lesions: a comparison of fine-needle aspiration, core, and open biopsy techniques. Diagn Cytopathol 2014 Jun;42(6):476-86. doi:10.1002/dc.23005. Epub 2014 Mar 19. PMID24644128.
    61. Jacques R, Kogon S, Shkrum M. An experimental model of tool mark striations by a serrated blade in human soft tissues. Am J Forensic Med Pathol59-61 doi:10.1097/PAF.00000000. PMID24457587.
    62. Bramwell VH, Tuck AB, Chapman JA, Anborgh PH, Postenka CO, Al-Katib W, Shepherd LE, Han L, Wilson CF, Pritchard KI, Pollak MN, Chambers AF. Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial. Breast Cancer ResR8 doi:10.1186/bcr3600. PMID24451146.
    63. Fok TC, Lapointe H, Tuck AB, Chambers AF, Jackson-Boeters L, Daley TD, Darling MR. Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin. Oral Surg Oral Med Oral Pathol Oral Radiol 320-9 doi:10.1016/j.oooo.2014. PMID25151586.
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