Publications

publications

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2020 Publications

    1. Abdollahi E, Champredon D, Langley JM, Galvani AP, Moghadas SM. Temporal estimates of case-fatality rate for COVID-19 outbreaks in Canada and the United States. CMAJ. 2020 Jun 22;192(25):E666-E670. doi: 10.1503/cmaj.200711. Epub 2020 May 22. PMID: 32444481
    2. Alfano R, Bauman GS, Liu W, Thiessen JD, Rachinsky I, Pavlosky W, Butler J, Gaed M, Moussa M, Gomez JA, Chin JL, Pautler S, Ward AD. Histologic validation of auto-contoured dominant intraprostatic lesions on [18F] DCFPyL PSMA-PET imaging. Radiother Oncol. 2020 Aug 19:S0167-8140(20)30726-X. doi: 10.1016/j.radonc.2020.08.008. Online ahead of print. PMID: 32827589
    3. Alotaibi F, Rytelewski M, Figueredo R, Zareardalan R, Zhang M, Ferguson PJ, Maleki Vareki S, Najajreh Y, El-Hajjar M, Zheng X, Min WP, Koropatnick J. CD5 blockade enhances ex vivo CD8+ T cell activation and tumour cell cytotoxicity. Eur J Immunol. 2020 Jan 15. doi: 10.1002/eji.201948309. PMID: 31943150
    4. Alsabbagh A,Robins TL, Harriman A, Jackson-Boeters L, Darling MR, Khan ZA, McCord C. Surrogate markers for high-risk human papillomavirus infection in oral epithelial dysplasia: A comparison of p16, Ki-67, and ProExC.  Oral Surg Oral Med Oral Pathol Oral Radiol. 2019 Oct 14. pii: S2212-4403(19)31507-X. doi: 10.1016/j.oooo.2019.09.019 PMID:  31902664
    5. Altesha MA, Ni T, Khan A, Liu K, Zheng X. Circular RNA in cardiovascular disease. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar;129(3):246-259.e1. doi: 10.1016/j.oooo.2019.09.019. Epub 2019 Oct 14. PMID: 30341894
    6. Amtul Z, Randhawa J, Najdat AN, Hill DJ, Arany EJ. Correction to: Role of delayed neuroglial activation in impaired cerebral blood flow restoration following comorbid injury. Cell Mol Neurobiol. 2020 Apr;40(3):381-382. doi: 10.1007/s10571-019-00739-8. PMID: 31599387
    7. Amtul Z, Frías C, Randhawa J, Hill DJ, Arany EJ.  The spatial cerebral damage caused by larger infarct and β-amyloid toxicity is driven by the anatomical/functional connectivity. J Comp Neurol. 2020 Jan 1;528(1):48-60. doi: 10.1002/cne.24738. Epub 2019 Jul 19. PMID: 31265125
    8. Amtul Z, Najdat AN, Hill DJ, Arany EJ. Differential temporal and spatial post-injury alterations in cerebral cell morphology and viability. J Comp Neurol. 2020 May 24. doi: 10.1002/cne.24955. Online ahead of print. PMID: 32447764
    9. Aref-Eshghi E, Biswas S, Chen C, Sadikovic B, Chakrabarti S. Glucose-induced duration-dependent genome-wide DNA methylation changes in human endothelial cells. Am J Physiol Cell Physiol. 2020 Aug 1;319(2):C268-C276. Epub 2020 May 27. doi: 10.1152/ajpcell.00011.2020. PMID: 32459505
    10. Aref-Eshghi E, Kerkhof J, Pedro VP, Barat-Houari M, Ruiz-Pallares N, Andrau J-, Lacombe D, Van-Gils J, Fergelot P, Dubourg C, Cormier-Daire V, Rondeau S, Lecoquierre F, Saugier-Veber P, Nicolas G, Lesca G, Chatron N, Sanlaville D, Vitobello A, Faivre L, Thauvin-Robinet C, Laumonnier F, Raynaud M, Alders M, Mannens M, Henneman P, Hennekam RC, Velasco G, Francastel C, Ulveling D, Ciolfi A, Pizzi S, Tartaglia M, Heide S, Héron D, Mignot C, Keren B, Whalen S, Afenjar A, Bienvenu T, Campeau PM, Rousseau J, Levy MA, Brick L, Kozenko M, Balci TB, Siu VM, Stuart A, Kadour M, Masters J, Takano K, Kleefstra T, de Leeuw N, Field M, Shaw M, Gecz J, Ainsworth PJ, Lin H, Rodenhiser DI, Friez MJ, Tedder M, Lee JA, DuPont BR, Stevenson RE, Skinner SA, Schwartz CE, Genevieve D, Sadikovic B, Groupe DI France. Evaluation of DNA methylation episignatures for diagnosis and phenotype correlations in 42 mendelian neurodevelopmental disorders. Am J Hum Genet. 2020 Mar 5;106(3):356-370. doi: 10.1016/j.ajhg.2020.01.019. Epub 2020 Feb 27. PMID: 32109418
    11. Aref-Eshghi E, McGee JD, Pedro VP, Kerkhof J, Stuart A, Ainsworth PJ, Lin H, Volodarsky M, McLachlin CM, Sadikovic B. Genetic and epigenetic profiling of BRCA1/2 in ovarian tumors reveals additive diagnostic yield and evidence of a genomic BRCA1/2 DNA methylation signature. J Hum Genet. 2020 Jun 1. doi: 10.1038/s10038-020-0780-4. [Epub ahead of print] PMID: 32483276
    12. Asadi F, Dhanvantari S. Stathmin-2 Mediates Glucagon Secretion From Pancreatic α-Cells. Front Endocrinol (Lausanne). 2020 Feb 4;11:29. doi: 10.3389/fendo.2020.00029. eCollection 2020. PMID: 32117057
    13. Awad SS, Touni AA, Gabril MY. Expression of immune checkpoints in active nonsegmental vitiligo: a pilot study. Int J Dermatol. 2020 Jun 18. doi: 10.1111/ijd.14983. [Epub ahead of print] PMID: 32557594
    14. Baranova K, Goebel EA, McGee J, Walsh JC. A Case of Synchronous Malignant and Benign Granular Cell Tumor of the Vulva. Int J Gynecol Pathol. 2020 Sep 17. doi: 10.1097/PGP.0000000000000712. Online ahead of print. PMID: 32947331
    15. Benedict L, Abidi M, Sandhu H, Gillespie A, Xue Q, Hill J, McKinley G. Evidence of stress and diabetes in indigenous peoples of Canada. University of Toronto Medical Journal. Volume 97, Issue 2, 2020, Pages 30-33.
    16. Berberich AJ, Wang J, Cao H, McIntyre AD, Spaic T, Miller DB, Stock S, Huot C, Stein R, Knoll J, Yang P, Robinson JF, Hegele RA. Simplifying Detection of Copy-Number Variations in Maturity-Onset Diabetes of the Young. Can J Diabetes. 2020 Jun 8:S1499-2671(20)30172-6. doi: 10.1016/j.jcjd.2020.06.001. Online ahead of print. PMID: 33011132
    17. Biswas S, Chakrabarti S. The multifaceted roles of lncRNAs in diabetic complications: a promising, yet perplexing paradigm. The chemical biology of long non-coding RNA (Barciszewski J. ed). Springer (in press).
    18. Budhram A, Dubey D, Sechi E, Flanagan E, Yang L, Bhayana V, McKeon A, Pittock S, Mills J. Neural antibody testing in patients with suspected autoimmune encephalitis. Clin Chem, Submitted, March 27, 2020
    19. Cameron L, Palikhe NS, Laratta C, Vliagoftis H. Elevated Circulating Th2 Cells in Women With Asthma and Psychological Morbidity: A New Asthma Endotype? Clin Ther. 2020 Jun;42(6):1015-1031. doi: 10.1016/j.clinthera.2020.05.001. Epub 2020 May 29. PMID: 32482491
    20. Cappuccio G, Sayou C, Tanno PL, Tisserant E, Bruel AL, Kennani SE, Sá J, Low KJ, Dias C, Havlovicová M, Hančárová M, Eichler EE, Devillard F, Moutton S, Van-Gils J, Dubourg C, Odent S, Gerard B, Piton A, Yamamoto T, Okamoto N, Firth H, Metcalfe K, Moh A, Chapman KA, Aref-Eshghi E, Kerkhof J, Torella A, Nigro V, Perrin L, Piard J, Le Guyader G, Jouan T, Thauvin-Robinet C, Duffourd Y, George-Abraham JK, Buchanan CA, Williams D, Kini U, Wilson K; Telethon Undiagnosed Diseases Program, Sousa SB, Hennekam RCM, Sadikovic B, Thevenon J, Govin J, Vitobello A, Brunetti-Pierri N. De novo SMARCA2 variants clustered outside the helicase domain cause a new recognizable syndrome with intellectual disability and blepharophimosis distinct from Nicolaides-Baraitser syndrome.  Genet Med. 2020 Jul 22. doi: 10.1038/s41436-020-0898-y. Online ahead of print. PMID: 32694869
    21. Champredon D, Shoukat A , Moghada, SM. Effectiveness and cost-effectiveness of a Clostridium difficile vaccine candidate in a hospital setting.  Vaccine. 2020 Feb 1. pii: S0264-410X(20)30115-8. doi: 10.1016/j.vaccine.2020.01.073.  PMID: 32014268
    22. Champredon D, Shoukat A, Singer BH, Galvani AP, Moghadas SM. Curbing the 2019 samoa measles outbreak. Lancet Infect Dis. 2020 Mar;20(3):287-288. doi: 10.1016/S1473-3099(20)30044-X. PMID: 32112762
    23. Chato C, Kalish ML, Poon AFY. Public health in genetic spaces: a statistical framework to optimize cluster-based outbreak detection. Virus Evol. 2020 Mar 13;6(1):veaa011. doi: 10.1093/ve/veaa011. eCollection 2020 Jan. PMID: 32190349
    24. Chin-Yee B, Sadikovic B, Chin-Yee IH. Genomic data in prognostic models-what is lost in translation? The case of deletion 17p and mutant TP53 in chronic lymphocytic leukaemia. Br J Haematol. 2020 Mar;188(5):652-660. DOI: 10.1111/bjh.15827 PMID: 30836431
    25. Chrisinger JSA, Wehrli B, Dickson BC, Fasih S, Hirbe AC, Shultz DB, Zadeh G, Gupta AA, Demicco EG. Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases. Virchows Arch. 2020 Jun 19. doi: 10.1007/s00428-020-02870-0. [Epub ahead of print] PMID: 32556562
    26. Ciolfi A, Aref-Eshghi E, Pizzi S, Pedace L, Miele E, Kerkhof J, Flex E, Martinelli S, Radio FC, Ruivenkamp CAL, Santen GWE, Bijlsma E, Barge-Schaapveld D, Ounap K, Siu VM, Kooy RF, Dallapiccola B, Sadikovic B, Tartaglia M. Frameshift mutations at the C-terminus of HIST1H1E result in a specific DNA hypomethylation signature. Clin Epigenetics. 2020 Jan 7;12(1):7. doi: 10.1186/s13148-019-0804-0.  PMID: 31910894
    27. Cox J, Khan Z, Jackson-Boeters L, Armstrong J, Darling M. Human Tissue Kallikreins in Polymorphous Adenocarcinoma: A Polymerase Chain Reaction and Immunohistochemical Study. Head Neck Pathol. 2020 Jun 26. doi: 10.1007/s12105-020-01196-2. Online ahead of print. PMID: 32592124
    28. Das S, Zhang Z, Ang LC. Clinicopathological overlap of neurodegenerative diseases: A comprehensive review. J Clin Neurosci. 2020 Apr 27. pii: S0967-5868(20)30460-4. doi: 10.1016/j.jocn.2020.04.088. [Epub ahead of print] PMID: 32354648
    29. Dawidek MT, Aquil S, Alogaili R, Gabril M, Moussa M, Sener A, Luke PP. Renal Lymphangiectasia in the Transplanted Kidney: Case Series and Literature Review. Transplantation. 2020 Jan;104(1):172-175. doi: 10.1097/TP.0000000000002745. PMID: 30964839
    30. Deller B, Solh Z, Hancock G, de Vrijer B. A false-positive kleihauer-betke test. J Obstet Gynaecol Can. 2020 Feb 5. pii: S1701-2163(19)30975-2. doi: 10.1016/j.jogc.2019.10.033. PMID: 32035718
    31. Deng S, Essandoh K, Wang X, Li Y, Huang W, Chen J, Peng J, Jiang DS, Mu X, Wang C, Peng T, Guan JL, Wang Y, Jegga A, Huang K, Fan GC. Tsg101 positively regulates P62-Keap1-Nrf2 pathway to protect hearts against oxidative damage. Redox Biol. 2020 Feb 6:101453. doi: 10.1016/j.redox.2020.101453. [Epub ahead of print] PMID: 32057709
    32. Di Gregorio SE, Volkening K, Strong MJDuennwald ML. Inclusion Formation and Toxicity of the ALS Protein RGNEF and Its Association with the Microtubule Network. Int J Mol Sci. 2020 Aug 5;21(16):E5597. doi: 10.3390/ijms21165597. DOI: 10.3390/ijms21165597 PMID: 32764283
    33. Dimassi AB, Howlett C, Phua CW. Multifocal CD4+ Primary Cutaneous Small/Medium Lymphoproliferative Disorder Successfully Treated With Low-Dose Oral Methotrexate: A Case Report.  Cureus. 2020 Jun 9;12(6):e8534. doi: 10.7759/cureus.8534. PMID: 32665881
    34. Dragan M, Nguyen MU, Guzman S, Goertzen C, Brackstone M, Dhillo WS, Bech PR, Clarke S, Abbara A, Tuck AB, Hess DA, Pine SR, Zong WX, Wondisford FE, Su X, Babwah AV Bhattacharya M.  G protein-coupled kisspeptin receptor induces metabolic reprograming and tumorigenesis in estrogen receptor-negative breast cancer.  Cell Death Dis. 2020 Feb 7;11(2):106. doi: 10.1038/s41419-020-2305-7.  PMID: 32034133
    35. Elzagallaai AA, Sultan EA, Bend JR, Abuzgaia AM, Loubani E, Rieder MJ. Role of Oxidative Stress in Hypersensitivity Reactions to Sulfonamides. J Clin Pharmacol. 2020 Mar;60(3):409-421. doi: 10.1002/jcph.1535  PMID: 31709574
    36. Filler G, Bhayana V, Schott C, Díaz-González de Ferris ME. How Should We Assess Renal Function in Neonates and Infants? Acta Paediatr. 2020 Aug 31. doi: 10.1111/apa.15557. Online ahead of print. PMID: 32869283
    37. Filler G, Medeiros M, Díaz-González de Ferris ME. Appreciating the Impact of Tacrolimus Sampling Time Deviations in Pediatric Patients With Nephrotic Syndrome. Ther Drug Monit. 2020 Jun;42(3):354-356. doi: 10.1097/FTD.0000000000000742. PMID: 32049892
    38. Filler GDíaz-González de Ferris ME. Automated Office Blood Pressure Measurement for the Diagnosis of Hypertension. J Pediatr. 2020 Jul 24;S0022-3476(20)30965-3. doi: 10.1016/j.jpeds.2020.07.066. PMID: 32712282 Online ahead of print.
    39. Fournier DE, Kiser PK, Beach RJ, Dixon SJ, Séguin CA. Dystrophic calcification and heterotopic ossification in fibrocartilaginous tissues of the spine in diffuse idiopathic skeletal hyperostosis (DISH). Bone Res 2020 Apr 2;8:16. doi: 10.1038/s41413-020-0091-6. eCollection 2020. PMID: 32257530
    40. Ghare A, Langdon KD, Kiwan R, Andrade A, Ranger A, Hammond R. Feeling green. Can J Neurol Sci [Internet]. 2020;47(2):245-50. DOI: 10.1017/cjn.2019.327
    41. Ghasemi F, Tessier TM, Gameiro SF, Maciver AH, Cecchini MJ, Mymryk JS. High MHC-II expression in Epstein-Barr virus-associated gastric cancers suggests that tumor cells serve an important role in antigen presentation. Sci Rep. 2020 Sep 8;10(1):14786. doi: 10.1038/s41598-020-71775-4. PMID: 32901107 
    42. Gillies R, Lee K, Vanin S, Laviolette SR, Holloway AC, Arany E, Hardy DB. Maternal exposure to Δ9-tetrahydrocannabinol impairs female offspring glucose homeostasis and endocrine pancreatic development in the rat. Reprod Toxicol. 2020 Apr 20. pii: S0890-6238(20)30120-9. doi: 10.1016/j.reprotox.2020.04.070. [Epub ahead of print] PMID: 32325173
    43. Halari MM, Shkrum MJ. The significance of a knee injury in the investigation of an unsuspected motor vehicle-pedestrian collision.  Am J Forensic Med Pathol. 2020 Mar;41(1):52-55. doi: 10.1097/PAF.0000000000000518.  PMID: 31895099
    44. Han W, Johnson C, Gaed M, Gómez JMoussa M, Chin J, Pautler S, Bauman GS, Ward AD. Histologic tissue components provide major cues for machine learning-based prostate cancer detection and grading on prostatectomy specimens. Sci Rep. 2020 Jun 18;10(1):9911. doi: 10.1038/s41598-020-66849-2. PMID: 32555410
    45. Han W, Johnson C, Warner A, Gaed M, Gomez JA, Moussa M, Chin J, Pautler S, Bauman G, Ward AD. Automatic cancer detection on digital histopathology images of mid-gland radical prostatectomy specimens. J Med Imaging (Bellingham). 2020 Jul;7(4):047501. doi: 10.1117/1.JMI.7.4.047501. Epub 2020 Jul 16. PMID: 32715024
    46. Hassan HM, Isovic M, Kolendowski B, Bauer-Maison N, Onabote O, Cecchini M, Haig A, Maleki Vareki S, Underhill TM, Torchia J. Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma. Cell Rep. 2020 Apr 7;31(1):107475. doi: 10.1016/j.celrep.2020.03.039 PMID: 32268085
    47. Higgins V, Patel K, Kulasingam V, Beriault DR, Rutledge AC, Selvaratnam R. Analytical performance evaluation of thyroid-stimulating hormone receptor antibody (TRAb) immunoassays. Clin Biochem. 2020 Aug 25:S0009-9120(20)30815-8. doi: 10.1016/j.clinbiochem.2020.08.007. Online ahead of print. PMID: 32858059
    48. Jones BR, Miller RL, Kinloch NN, Tsai O, Rigsby H, Sudderuddin H, Shahid A, Ganase B, Brumme CJ, Harris M, Poon AFY, Brockman MA, Fromentin R, Chomont N, Joy JB, Brumme ZL. Genetic Diversity, Compartmentalization, and Age of HIV Proviruses Persisting in CD4+ T Cell Subsets during Long-Term Combination Antiretroviral Therapy.  J Virol. 2020 Feb 14;94(5). pii: e01786-19. doi: 10.1128/JVI.01786-19  PMID: 31776273
    49. Joshi R, Qin L, Cao X, Zhong S, Voss C, Min W, Li SSC. DLC1 SAM domain-binding peptides inhibit cancer cell growth and migration by inactivating RhoA. J Biol Chem. 2020 Jan 10;295(2):645-656. doi: 10.1074/jbc.RA119.011929. Epub 2019 Dec 5. PMID: 31806702
    50. Kadatz M, Payne M, Kiaii M, Romney MG, Karakas L, Lawson T, Marchuk S, Gill J, Lowe CF. Utility of Rapid Influenza Molecular Testing in an Outpatient Hemodialysis Unit: A Prospective Cohort Study. Can J Kidney Health Dis. 2020 Feb 26;7:2054358120907816. doi: 10.1177/2054358120907816. eCollection 2020. PMID: 32153798
    51. Kansal V, Armstrong JJ, Hutnik CML. Trends in glaucoma filtration procedures: A retrospective administrative health records analysis over a 13-year period in canada. Clin Ophthalmol. 2020 Feb 20;14:501-508. doi: 10.2147/OPTH.S232873. eCollection 2020. PMID: 32109986
    52. Kawata E, Chin-Yee I, Hsia C, Solh Z.  IgA-mediated autoimmune hemolytic anemia. Am J Hematol. 2020 Jan;95(1):129-130. doi: 10.1002/ajh.25581. Epub 2019 Aug 16. PMID: 31328297.
    53. Kawata E, Lazo-Langner A, Xenocostas A, Hsia CC, Howson-Jan K, Deotare U, Saini L, Yang P, Broadbent R, Levy M, Howlett C, Stuart A, Kerkhof J, Santos S, Lin H, Sadikovic B, Chin-Yee I. Clinical value of next-generation sequencing compared to cytogenetics in patients with suspected myelodysplastic syndrome. Br J Haematol. 2020 Jun 25. doi: 10.1111/bjh.16891. [Epub ahead of print] PMID: 32588428
    54. Keow JY, Stecho WM, Haig AR, Sangle NA. EBV-positive T/NK-associated lymphoproliferative disorders of childhood: A complete autopsy report. Indian J Pathol Microbiol. 2020 Jan-Mar;63(1):78-82. doi: 10.4103/IJPM.IJPM_510_19. PMID: 32031127
    55. Knauer MJ, Hedley BD, Bhayana V, Payne M, Chin-Yee I, Delport J. Interim analysis of the clinical performance of five SARS-Cov-2 serology assays. Clin Biochem. 2020 Sep 6:S0009-9120(20)30837-7. doi: 10.1016/j.clinbiochem.2020.09.002. Online ahead of print. PMID: 32905808 Free PMC article. No abstract available.
    56. Kosakovsky Pond SL, Poon AFY, Velazquez R, Weaver S, Hepler NL, Murrell B, Shank SD, Magalis BR, Bouvier D, Nekrutenko A, Wisotsky S, Spielman SJ, Frost SDW, Muse SV.  HyPhy 2.5-A Customizable Platform for Evolutionary Hypothesis Testing Using Phylogenies. Mol Biol Evol. 2020 Jan 1;37(1):295-299. doi: 10.1093/molbev/msz197. PMID: 31504749
    57. Krstic M, Hassan HM, Kolendowski B, Hague MN, Anborgh PH, Postenka CO, Torchia J, Chambers AFTuck AB. Isoform-specific promotion of breast cancer tumorigenicity by TBX3 involves induction of angiogenesis. Lab Invest. 2020 Mar;100(3):400-413. doi: 10.1038/s41374-019-0326-6. Epub 2019 Sep 30. PMID: 31570773
    58. Lan T, Tao A, Xu X, Kvietys P, Rui T. Peroxynitrite/PKR Axis Modulates the NLRP3 Inflammasome of Cardiac Fibroblasts. Front Immunol. 2020 Sep 25;11:558712. doi: 10.3389/fimmu.2020.558712. eCollection 2020. PMID: 33101273
    59. Li Y, Deng S, Wang X, Huang W, Chen J, Robbins N, Mu X, Essandoh K, Peng T, Jegga AG, Rubinstein J, Adams DE, Wang Y, Peng J, Fan GC. Sectm1a Deficiency Aggravates Inflammation-Triggered Cardiac Dysfunction through Disruption of LXRα Signaling in Macrophages. Cardiovasc Res. 2020 Mar 14. pii: cvaa067. doi: 10.1093/cvr/cvaa067. [Epub ahead of print] PMID: 32170929
    60. Liu J, Chen S, Biswas S, Nagrani N, Chu Y2, Chakrabarti S, Feng B. Glucose-induced oxidative stress and accelerated aging in endothelial cells are mediated by the depletion of mitochondrial SIRTs.  Physiol Rep. 2020 Feb;8(3):e14331. doi: 10.14814/phy2.14331.  PMID: 32026628
    61. Liu Y, Tan M, Zhang Y, Huang W, Min L, Peng S, Yuan K, Qiu L, Min W. Targeted Gene Silencing BRAF Synergized Photothermal Effect Inhibits Hepatoma Cell Growth Using New GAL-GNR-siBRAF Nanosystem. Nanoscale Res Lett. 2020 May 24;15(1):116. doi: 10.1186/s11671-020-03340-x. PMID: 32449085
    62. Liu Z, Ji J, Zheng D, Su L, Peng T, Tang J. Protective role of endothelial calpain knockout in lipopolysaccharide-induced acute kidney injury via attenuation of the p38-iNOS pathway and NO/ROS production. Exp Mol Med. 2020 Apr;52(4):702-712. doi: 10.1038/s12276-020-0426-9. Epub 2020 Apr 28. PMID: 32346126
    63. Logan LK, Nguyen DC, Scaggs Huang FA, Qureshi NK, Charnot-Katsikas A, Bartlett AH, Zheng X, Hujer AM, Domitrovic TN, Marshall SH, Bonomo RA, Weinstein RA. A Multi-Centered Case-Case-Control Study of Factors Associated With Klebsiella pneumoniae Carbapenemase-Producing Enterobacteriaceae Infections in Children and Young Adults. Pediatr Infect Dis J. 2019 May;38(5):490-495. doi: 10.1097/INF.0000000000002176. PMID: 30169484
    64. Lu H, Chen R, Amoah Barnie P, Tian Y, Zhang S, Ca Y, Xu H, Chakrabarti S, Su Z. Fibroblast transdifferentiation promotes conversion of infiltrated proinflammatory macrophages and replenishment of cardiac resident macrophages following cardiac injury. Eur J Immunol. 2020 Jun;50(6):795-808.
       doi: 10.1002/eji.201948414. Epub 2020 Feb 25. PMID: 32068249
    65. MacPherson M, Pho M, Cox J, Armstrong J, Darling MR, McCord C. Ligneous gingivitis secondary to plasminogen deficiency: a multidisciplinary diagnostic challenge. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Mar 12. pii: S2212-4403(19)31640-2. doi: 10.1016/j.oooo.2019.12.014. [Epub ahead of print]. PMID: 32173395
    66. Maki Y, Nygard K, Hammond R, Regnault TRH, Richardson BS. Maternal Undernourishment in Guinea Pigs Leads to Fetal Growth Restriction With Increased Hypoxic Cells and Oxidative Stress in the Brain. Dev Neurosci. 2020 Apr 21;1-10. doi: 10.1159/000506939. Online ahead of print. PMID: 32316015.
    67. Mann JFS, Pankrac J, Klein K, McKay PF, King DFL, Gibson R, Wijewardhana CN, Pawa R, Meyerowitz J, Gao Y, Canaday DH, Avino M, Poon AFY, Foster C, Fidler S, Shattock RJ, Arts EJ. A targeted reactivation of latent HIV-1 using an activator vector in patient samples from acute infection. EBioMedicine. 2020 Jul 9:102853. Online ahead of print. doi: 10.1016/j.ebiom.2020.102853. PMID: 32654992
    68. Marshall AE, Ishak CA, Dick FA. An RB-Condensin II Complex Mediates Long-Range Chromosome Interactions and Influences Expression at Divergently Paired Genes.  Mol Cell Biol. 2020 Jan 3;40(2). pii: e00452-19. doi: 10.1128/MCB.00452-19. Print 2020 Jan 3. PMID: 31685548
    69. McKinley G. Reflections on being a learner: The value of relationship-based community evaluations in indigenous communities. Can J Program Eval [Internet]. 2020;34(3):464-79.
    70. McKinley GP. We need each other: Social supports during COVID 19. Social Anthropology. 02 June 2020. https://doi.org/10.1111/1469-8676.12828
    71. Medeiros B, Goodale D, Postenka C, Lowes LE, Kiser P, Hearn S, Salmond N, Williams KC, Allan AL. Triple-negative primary breast tumors induce supportive premetastatic changes in the extracellular matrix and soluble components of the lung microenvironment. Cancers (Basel). 2020 Jan 10;12(1). pii: E172. doi: 10.3390/cancers12010172. PMID: 31936750
    72. Mishra A, Corkum MT, Pautler SE, Wehrli B, Winquist E. Images - Solitary fibrous tumor of the prostate. Can Urol Assoc J. 2020 Jun 5. doi: 10.5489/cuaj.6289. [Epub ahead of print] PMID: 32520705
    73. Naeem A, Kubica M, Namavarian A, Pandey S, Zhang Q. A 63-year-old male with cauda equina syndrome. Brain Pathol. 2020 Mar;30(2):409-410. doi: 10.1111/bpa.12816. PMID: 32100429
    74. Nair SM, Stern N, Dewar M, Siddiqui K, Smith E, Gomez JA, Moussa M, Chin JL. Salvage open radical prostatectomy for recurrent prostate cancer following MRI-guided transurethral ultrasound ablation (TULSA) of the prostate: feasibility and efficacy. Scand J Urol. 2020 Apr 20:1-5. doi: 10.1080/21681805.2020.1752795. [Epub ahead of print] PMID: 32308085
    75. Ndashimye E, Avino M, Olabode AS, Poon AFY, Gibson RM, Li Y, Meadows A, Tan C, Reyes PS, Kityo CM, Kyeyune F, Nankya I, Quiñones-Mateu ME, Arts EJ. Accumulation of integrase strand transfer inhibitor resistance mutations confers high-level resistance to dolutegravir in non-B subtype HIV-1 strains from patients failing raltegravir in Uganda. J Antimicrob Chemother. 2020 Aug 27:dkaa355. doi: 10.1093/jac/dkaa355. Online ahead of print. PMID: 32853364
    76. Nichols AC, Lang P, Prisman E, Berthelet E, Tran E, Hamilton S, Wu J, Fung K, de Almeida JR, Bayley A, Goldstein DP, Eskander A, Husain Z, Bahig H, Christopoulous A, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Mendez A, Winquist E, Read N, Venkatesan V, Kuruvilla S, Warner A, Mitchell S, Corsten M, Rajaraman M, Johnson-Obaseki S, Eapen L, Odell M, Chandarana S, Banerjee R, Dort J, Matthews TW, Hart R, Kerr P, Dowthwaite S, Gupta M, Zhang H, Wright J, Parker C, Wehrli B, Kwan K, Theurer J, Palma DA.  Treatment de-escalation for HPV-associated oropharyngeal squamous cell carcinoma with radiotherapy vs. trans-oral surgery (ORATOR2): study protocol for a randomized phase II trial.  BMC Cancer. 2020 Feb 14;20(1):125. doi: 10.1186/s12885-020-6607-z.  PMID: 32059705
    77. Oakie A, Zhou L, Rivers S, Cheung C, Li J, Wang R.  Postnatal knockout of beta cell insulin receptor impaired insulin secretion in male mice exposed to high-fat diet stress. Mol Cell Endocrinol. 2020 Jan 1;499:110588. doi: 10.1016/j.mce.2019.110588. Epub 2019 Sep 18.  PMID: 31541682
    78. Park SW, Bolker BM, Champredon D, Earn DJD, Li M, Weitz JS, Grenfell BT, Dushoff J. Reconciling early-outbreak estimates of the basic reproductive number and its uncertainty: framework and applications to the novel coronavirus (SARS-CoV-2) outbreak. J R Soc Interface. 2020 Jul;17(168):20200144. Epub 2020 Jul 22. doi: 10.1098/rsif.2020.0144. PMID: 32693748 
    79. Pejhan S, Mok Siu V, Ang LC, Del Bigio MR, Rastegar M. Differential brain region-specific expression of MeCP2 and BDNF in Rett Syndrome patients: A distinct grey-white matter variation. Neuropathol Appl Neurobiol. 2020 Apr 4. doi: 10.1111/nan.12619. [Epub ahead of print]. PMID: 32246495
    80. Perampalam P, Dick FA. BEAVR: A Browser-Based Tool for the Exploration and Visualization of RNA-seq Data. BMC Bioinformatics. 2020 May 29;21(1):221. doi: 10.1186/s12859-020-03549-8. PMID: 32471392
    81. Rabbani M, Hafiz A, Algadheeb M, Tugaleva E, Bergin ML, Ray Guo L-R. Pulmonary Artery Intimal Sarcoma: A Deadly Diagnosis in Disguise. CJC Open 2020.
    82. Restrepo JM, Torres-Canchala L, Viáfara LM, Agredo MA, Quintero AM, Filler G. Renal Length z-score for the Detection of Dysfunction in Children with Solitary Functioning Kidney. Acta Paediatr. 2020 Jun 22. doi: 10.1111/apa.15425. [Epub ahead of print] PMID: 32570288
    83. Rhudy JL, Huber F, Kuhn BL, Lannon EW, Palit S, Payne MF, Hellman N, Sturycz CA, Güereca YM, Toledo TA, Demuth MJ, Hahn BJ, Shadlow JO. Pain-related anxiety promotes pronociceptive processes in Native Americans: bootstrapped mediation analyses from the Oklahoma Study of Native American Pain Risk. Pain Rep. 2020 Jan 27;5(1):e808. doi: 10.1097/PR9.0000000000000808. eCollection 2020 Jan-Feb. PMID: 32072102
    84. Rogan P,  Mucaki E, Lu R, Shirley B, Waller E, Knoll J. Meeting Radiation Dosimetry Capacity Requirements of Population-Scale Exposures by Geostatistical Sampling. PLoS One. 2020 Apr 24;15(4):e0232008. doi: 10.1371/journal.pone.0232008. eCollection 2020. PMID: 32330192
    85. Roseborough AD, Langdon KD, Hammond R, Cipriano L, Pasternak S, Whitehead SN, Khan AR. Post-mortem 7 Tesla MRI detection of white matter hyperintensities: A multidisciplinary voxel-wise comparison of imaging and histological correlates. Neuroimage Clin. 2020 Jul 6;27:102340. doi: 10.1016/j.nicl.2020.102340. Online ahead of print. PMID: 32679554
    86. Rudnick W, Science M, Thirion DJG, Abdesselam K, Choi KB, Pelude L, Amaratunga K, Comeau JL, Dalton B, Delport J, Dhami R, Embree J, Émond Y, Evans G, Frenette C, Fryters S, German G, Grant JM, Happe J, Katz K, Kibsey P, Kosar J, Langley JM, Lee BE, Lefebvre MA, Leis JA, McGeer A, Neville HL, Simor A, Slayter K, Suh KN, Tse-Chang A, Weiss K, Conly J; Canadian Nosocomial Infection Surveillance Program. Antimicrobial use among adult inpatients at hospital sites within the Canadian Nosocomial Infection Surveillance Program: 2009 to 2016. Antimicrob Resist Infect Control. 2020 Feb 13;9(1):32. doi: 10.1186/s13756-020-0684-2. PMID: 32054539
    87. Ruicci KM, Meens J, Plantinga P, Stecho W, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Howlett CJ, Boutros PC, Ailles L, Nichols AC. TAM family receptors in conjunction with MAPK signalling are involved in acquired resistance to PI3Kα inhibition in head and neck squamous cell carcinoma. J Exp Clin Cancer Res. 2020 Oct 15;39(1):217. doi: 10.1186/s13046-020-01713-9. PMID: 33059733 
    88. Sadikovic B, Levy MA, Aref-Eshghi E. Functional annotation of genomic variation: DNA methylation episignatures in neurodevelopmental Mendelian disorders. Hum Mol Genet. 2020 Jul 9:ddaa144. doi: 10.1093/hmg/ddaa144. Online ahead of print. PMID: 32644126
    89. Sallam YT, Zhang Q, Pandey SK. Cortically based cystic supratentorial RELA fusion-positive ependymoma: a case report with unusual presentation and appearance and review of literature. Radiol Case Rep. 2020 Oct 2;15(12):2495-2499. doi: 10.1016/j.radcr.2020.09.022. eCollection 2020 Dec. PMID: 33033550
    90. Schünemann HJ, Ventresca M, Crowther M, Briel M, Zhou Q, Noble S, Macbeth F, Griffiths G, Garcia D, Lyman GH, Di Nisio M, Iorio A, Mbuagbaw L, Neumann I, van Es N, Brouwers M, Guyatt G, Streiff MB, Marcucci M, Baldeh T, Florez ID, Alma OG, Solh Z, Bossuyt PM, Kahale LA, Ageno W, Bozas G, Büller HR, Lebeau B, Lecumberri R, Loprinzi C, McBane R, Sideras K, Maraveyas A, Pelzer U, Perry J, Klerk C, Agnelli G, Akl EA. Evaluating prophylactic heparin in ambulatory patients with solid tumours: a systematic review and individual participant data meta-analysis. Lancet Haematol. 2020 Oct;7(10):e746-e755. doi: 10.1016/S2352-3026(20)30293-3. PMID: 32976752
    91. Shirley BC, Knoll JHM, Moquet J, Ainsbury E, Pham ND, Norton F, Wilkins RC, Rogan PK. Estimating partial-body ionizing radiation exposure by automated cytogenetic biodosimetry. Int J Radiat Biol. 2020 Oct 6:1-12. doi: 10.1080/09553002.2020.1820611. Online ahead of print. PMID: 32910711
    92. Shrestha Palikhe N, Wu Y, Konrad E, Gandhi VD, Rowe BH, Vliagoftis H, Cameron L. Th2 cell markers in peripheral blood increase during an acute asthma exacerbation. Allergy. 2020 Aug 4. doi: 10.1111/all.14543. Online ahead of print. PMID: 32750154
    93. Sogutdelen E, Pacoli K, Juriasingani S, Akbari M, Gabril M, Sener A. Patterns of Expression of H2S-Producing Enzyme in Human Renal Cell Carcinoma Specimens: Potential Avenue for Future Therapeutics. In Vivo. 2020 Sep-Oct;34(5):2775-2781. doi: 10.21873/invivo.12102. PMID: 32871814
    94. Squizzato A, Gallo A, Levi M, Iba T, Levy JH, Erez O, Ten Cate H, Solh Z, Gando S, Vicente V, Di Nisio M. Underlying disorders of disseminated intravascular coagulation: Communication from the ISTH SSC Subcommittees on Disseminated Intravascular Coagulation and Perioperative and Critical Care Thrombosis and Hemostasis. J Thromb Haemost. 2020 Sep;18(9):2400-2407. doi: 10.1111/jth.14946. PMID: 32881338
    95. Su N, Poon R, Liu C, Dewan C, Darling M, Grushka M. Pain reduction in burning mouth syndrome (BMS) may be associated with selective improvement of taste: a retrospective study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 May;129(5):461-467. doi: 10.1016/j.oooo.2020.02.001. Epub 2020 Mar 5. PMID: 32147381
    96. Surak A, Filler G, Sharma AP, Torres Canchala LA, Grattan M. Lower Prevalence of Aortic Dilatation Among Preemptive Pediatric Renal Transplant Recipients - A Cross-Sectional Cohort Study. Pediatr Transplant. 2020 May 11;e13716. doi: 10.1111/petr.13716. Online ahead of print. PMID: 32390244
    97. Suzuki M, Yokota M, Kanemitsu Y, Min WP, Ozaki S, Nakamura Y. Intranasal administration of regulatory dendritic cells is useful for the induction of nasal mucosal tolerance in a mice model of allergic rhinitis. World Allergy Organ J. 2020 Aug 11;13(8):100447. doi: 10.1016/j.waojou.2020.100447. eCollection 2020 Aug. PMID: 32817781
    98. Tai F, Chin-Yee I, Gob A, Bhayana V, Rutledge A. Reducing overutilization of serum vitamin D testing at a tertiary care centre. BMJ Open Qual, 2020 Apr 1; 9 (1): e000929, DOI: 10.1136/bmjoq-2020-000929
    99. Tao G, Miller WC, Eng JJ, Lindstrom H, Imam B, Payne M. Self-directed usage of an in-home exergame after a supervised telerehabilitation training program for older adults with lower-limb amputation. Prosthet Orthot Int. 2020 Apr;44(2):52-59. doi: 10.1177/0309364620906272. Epub 2020 Mar 1. PMID: 32114933
    100. Tao J, Rupar CA, Miller MR, Ratko S, Prasad C. Use of complementary and alternative medicine in patients with inborn errors of metabolism: A single-center study. JIMD Rep. 2019 Dec 18;51(1):105-112. doi: 10.1002/jmd2.12089. eCollection 2020 Jan. PMID: 32071845
    101. Taqui B, Asadi F, Capobianco E, Hardy DB, Jawerbaum A, Arany EJ. Olive oil diet in mild pre-gestational diabetes impacts offspring β-cell development. J Endocrinol. 2020 Jun 1. pii: JOE-20-0047.R2. doi: 10.1530/JOE-20-0047. [Epub ahead of print] PMID: 32485676
    102. Tarnopolsky MA, Kerkhof J, Stuart A, Bujak A, Nilsson MI, Hettinga B, May L, Rupar CA, Sadikovic B. Bone marrow-derived mitochondrial DNA has limited capacity for inter-tissue transfer in vivo. FASEB J. 2020 May 22. doi: 10.1096/fj.202000463R. [Epub ahead of print] PMID: 32441840
    103. Toledo TA, Kuhn BL, Payne MF, Lannon EW, Palit S, Sturycz CA, Hellman N, Güereca YM, Demuth MJ, Huber F, Shadlow JO, Rhudy JL. The Effect of Pain Catastrophizing on Endogenous Inhibition of Pain and Spinal Nociception in Native Americans: Results From the Oklahoma Study of Native American Pain Risk. Ann Behav Med. 2020 Feb 19. pii: kaaa004. doi: 10.1093/abm/kaaa004. [Epub ahead of print] PMID: 32073117
    104. Tran C, Howlett C, Driman DK. Evaluating the Impact of Lymph Node Resampling on Colorectal Cancer Nodal Stage.  Histopathology. 2020 Jul 11. doi: 10.1111/his.14209. Online ahead of print. PMID: 32654207
    105. Trelford CB, Denstedt JT, Armstrong JJ, Hutnik CML. The pro-fibrotic behavior of human Tenon’s capsule fibroblasts in medically treated glaucoma patients. Clin Ophthalmol. 2020 May 22;14:1391-1402. doi: 10.2147/OPTH.S245915. eCollection 2020. PMID: 32546947
    106. Vasanthamohan L, Choo S, Marshall T, Symons YT, Matsui D, Eastabrook G, Solh Z. Peripartum hyperhemolysis prophylaxis and management in sickle cell disease: A case report and narrative review. Transfusion. 2020 Aug 26. doi: 10.1111/trf.16003. Online ahead of print. PMID: 32851670
    107. van Es N, Ventresca M, Di Nisio M, Zhou Q, Noble S, Crowther M, Briel M, Garcia D, Lyman GH, Macbeth F, Griffiths G, Iorio A, Lawrence M, Neumann I, Brozek J, Guyatt G, Streiff MB, Baldeh T, Florez ID, Alma OG, Agnelli G, Ageno W, Marcucci M, Bozas G, Zulian G, Maraveyas A, Lebeau B, Lecumberri R, Sideras K, Loprinzi C, McBane R, Pelzer U, Riess H, Solh Z, Perry J, Kahale LA, Bossuyt PM, Klerk C, Büller HR, Akl EA, Schünemann HJ; IPDMA heparin use in cancer patients research group. The Khorana score for prediction of venous thromboembolism in cancer patients: an individual patient data meta-analysis. J Thromb Haemost. 2020 Apr 26. doi: 10.1111/jth.14824. [Epub ahead of print] PMID: 32336010
    108. Veldhuizen R, Baer B, McCaig L, Solomon LA, Cameron L, Hardy DB. The effect of maternal protein restriction during perinatal life on the inflammatory response in pediatric rats. Can J Physiol Pharmacol. 2020 Sep 11. doi: 10.1139/cjpp-2020-0431. Online ahead of print. PMID: 32916058
    109. Verma S, Chanchlani R, Siu VM, Filler G. Transient hyponatremia of prematurity caused by mild Bartter syndrome type II: a case report. BMC Pediatr. 2020 Jun 26;20(1):311. doi: 10.1186/s12887-020-02214-6. PMID: 32590952
    110. Vilos GA, Vilos AG, Hollett-Caines J, Abu-Rafea B, Jacob GP, Ettler H. Retroperitoneal pelvic tumours in women: diagnostic and therapeutic challenges. Facts Views Vis Obgyn. 2020 Mar 27;11(4):299-306. PMID: 32322825
    111. Virine B, Chande N, Driman D. Biopsies From Ascending and Descending Colon Are Sufficient for Diagnosis of Microscopic Colitis. Clin Gastroenterol Hepatol. 2020 Aug;18(9):2003-2009. doi: 10.1016/j.cgh.2020.02.036. Epub 2020 Feb 25. PMID: 32109628
    112. Volodarsky M, Kerkhof J, Stuart A, Levy M, Brady LI, Tarnopolsky M, Lin H, Ainsworth P, Sadikovic B. Comprehensive genetic sequence and copy number analysis for Charcot-Marie-Tooth disease in a Canadian cohort of 2517 patients. J Med Genet. 2020 May 6. pii: jmedgenet-2019-106641. doi: 10.1136/jmedgenet-2019-106641. [Epub ahead of print] PMID: 32376792
    113. Wang L, Li Y, Wang X, Wang P, Essandoh K, Cui S, Huang W, Mu X, Liu Z, Wang Y, Peng T, Fan G. Growth differentiated factor 3 protects against endotoxin-induced cardiac dysfunction and mortality through the activation of Smad2/3 in tissue repairing macrophages. Cells 2020; 9(1). pii: E120.
    114. Wang Y, Luo W, Han J, Khan Z, Fang Q, Jin Y, Chen X, Zhang Y, Wang M, Qian J, Huang W, Lum H, Wu G, Liang G. MD2 Activation by Direct AGE Interaction Drives Inflammatory Diabetic Cardiomyopathy. Nat Commun. 2020 May 1;11(1):2148. doi: 10.1038/s41467-020-15978-3. PMID: 32358497
    115. Wilk P, Ali S, Anderson KK, Clark AF, Cooke M, Frisbee SJ, Gilliland J, Haan M, Harris S, Kiarasi S, Maltby A, Norozi K, Petrella R, Sarma S, Singh SS, Stranges S, Thind A. Geographic variation in preventable hospitalisations across Canada: a cross-sectional study. BMJ Open. 2020 May 15;10(5):e037195. doi: 10.1136/bmjopen-2020-037195. PMID: 32414831
    116. Win PW, Oakie A, Li J, Wang R.  Beta-cell β1 integrin deficiency affects in utero development of islet growth and vascularization.  Cell Tissue Res. 2020 Feb 15. doi: 10.1007/s00441-020-03179-9. PMID: 32060653
    117. Yao T, Shooshtari P, Haeryfar SMM. Leveraging Public Single-Cell and Bulk Transcriptomic Datasets to Delineate MAIT Cell Roles and Phenotypic Characteristics in Human Malignancies. Front Immunol. 2020 Jul 31;11:1691. doi: 10.3389/fimmu.2020.01691. eCollection 2020. PMID: 32849590
    118. Zhang S, Chen R, Chakrabarti S, Su Z. Resident macrophages as potential therapeutic targets for cardiac ageing and injury. Clin Transl Immunology. 2020 Aug 26;9(8):e1167. doi: 10.1002/cti2.1167. eCollection 2020. PMID: 32874584
    119. Zhang M, Shi Y, Zhang Y, Wang Y, Alotaibi F, Qiu L, Wang H, Peng S, Liu Y, Li Q, Gao D, Wang Z, Yuan K, Dou F-, Koropatnick J, Xiong J, Min W. miRNA-5119 regulates immune checkpoints in dendritic cells to enhance breast cancer immunotherapy. Cancer Immunol Immunother. 2020 Feb 20. doi: 10.1007/s00262-020-02507-w. PMID: 32076794
    120. Zhang Y, Feng Y, Huang Y,  Wang Y, Qiu L, Liu Y , Peng S, Li R, Kuang N, Shi Q, Shi Y, Chen Y, Joshi R, Wang Z, Yuan K, Min W. Tumor-Targeted Gene Silencing IDO Synergizes PTT-Induced Apoptosis and Enhances Anti-tumor Immunity. Front Immunol. 2020 Jun 9;11:968. doi: 10.3389/fimmu.2020.00968. eCollection 2020. PMID: 32582152
    121. Zhang Y, Li Y, Huang X, Zhang F, Tang L, Xu S, Liu Y, Tong N, Min W. Systemic Delivery of siRNA Specific for Silencing TLR4 Gene Expression Reduces Diabetic Cardiomyopathy in a Mouse Model of Streptozotocin-Induced Type 1 Diabetes. Diabetes Ther. 2020 May;11(5):1161-1173. doi: 10.1007/s13300-020-00802-4. Epub 2020 Apr 13. PMID: 32285313
    122. Zhao D, Zheng H, Greasley A, Ling F, Zhou Q, Wang B, Ni T, Topiwala I, Zhu C, Mele T, Liu K, Zheng X. The role of miR-711 in cardiac cells in response to oxidative stress and its biogenesis: a study on H9C2 cells. Cell Mol Biol Lett. 2020 Apr 9;25:26. doi: 10.1186/s11658-020-00206-z. eCollection 2020. DOI: 10.1186/s11658-020-00206-z  PMID: 32308692
    123. Zhao D, Zheng H, Ni T, Topiwala I, McAlister V, Mele T, Liu K, Zheng X.(2020). The regulatory function of miRNA-711 by HIF-1 and NFKB in cardiomyocytes under stress.  Cellular and Molecular Research Letter. 2020, 25:26 https://doi.org/10.1186/s11658-020-00206-z 2020. Contributions: Idea generation, experimental design, data analysis, and manuscript writing and revision.
    124. Zhao X, Chen D, Szabla R, Zheng M, Li G, Du P, Zheng S, Li X, Song C, Li R, Guo JT, Junop M, Zeng H, Lin H. Broad and differential animal ACE2 receptor usage by SARS-CoV-2.  J Virol. 2020 Jul 13:JVI.00940-20. doi: 10.1128/JVI.00940-20. Online ahead of print. PMID: 32661139
    125. Zhao X, Zheng S, Chen D, Zheng M, Li X, Li G, Lin H, Chang J, Zeng H, Guo JT. LY6E Restricts the Entry of Human Coronaviruses, Including the Currently Pandemic SARS-CoV-2. J Virol. 2020 Jul 8:JVI.00562-20. doi: 10.1128/JVI.00562-20. Online ahead of print. PMID: 32641482
    126. Zheng H, Baranova K, Song J, Yan L, Biswas S, Chakrabarti S, Zhang Q. Overexpression of Long Noncoding RNA HOTAIR Is a Unique Epigenetic Characteristic of Myxopapillary Ependymoma. J Neuropathol Exp Neurol. 2020 Sep 17:nlaa103. doi: 10.1093/jnen/nlaa103. Online ahead of print. PMID: 32940681
    127. Zheng M, Zhao X, Zheng S, Chen D, Du P, Li X, Jiang D, Guo JT, Zeng H, Lin H. Bat SARS-Like WIV1 coronavirus uses the ACE2 of multiple animal species as receptor and evades IFITM3 restriction via TMPRSS2 activation of membrane fusion. Emerg Microbes Infect. 2020 Jun 30:1-36. doi: 10.1080/22221751.2020.1787797. [Epub ahead of print] PMID: 32602823

2019 Publications

    1. Ahmed S, Bogiatzi C, Hackam DG, Rutledge AC, Sposato LA, Khaw A, Mandzia J, Azarpazhoo MR, Hachinski V, Spence JD. Vitamin B12 deficiency and hyperhomocysteinaemia in outpatients with stroke or transient ischaemic attack: A cohort study at an academic medical centre. BMJ Open. 2019;9(1) DOI: 10.1136/bmjopen-2018-026564. PMID: 30670531
    2. Alfano R, Soetemans D, Bauman GS, Gaed M, Moussa M, Gomez JA, Chin JL, Pautler S, Ward AD. Texture-based prostate cancer classification on MRI: How does inter-class size mismatch affect measured system performance? In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE; 2019 DOI: 10.1117/12.2513301.
    3. Amtul Z, Randhawa J, Najdat AN, Hill DJ, Arany EJ. Role of Delayed Neuroglial Activation in Impaired Cerebral Blood Flow Restoration Following Comorbid Injury.  Cell Mol Neurobiol. 2019 Sep 14. doi: 10.1007/s10571-019-00735-y. [Epub ahead of print]  PMID:  31522299
    4. Aref-Eshghi E, Bend EG, Colaiacovo S, Caudle M, Chakrabarti R, Napier M, Brick L, Brady L, Carere DA, Levy MA, Kerkhof J, Stuart A, Saleh M, Beaudet AL, Li C, Kozenko M, Karp N, Prasad C, Siu VM, Tarnopolsky MA, Ainsworth PJ, Lin H, Rodenhiser DI, Krantz ID, Deardorff MA, Schwartz CE, Sadikovic B. Diagnostic utility of genome-wide DNA methylation testing in genetically unsolved individuals with suspected hereditary conditions. Am J Hum Genet. 2019;104(4):685-700. DOI: 10.1016/j.ajhg.2019.03.008. PMID: 30929737 
    5. Aref-Eshghi E, Bourque DK, Kerkhof J, Carere DA, Ainsworth P, Sadikovic B, Armour CM, Lin H.  Genome-wide DNA methylation and RNA analyses enable reclassification of two variants of uncertain significance in a patient with clinical Kabuki syndrome.  Hum Mutat. 2019 Oct;40(10):1684-1689. doi: 10.1002/humu.23833. Epub 2019 Jul 3.  PMID:  31268616
    6. Armstrong JJ, Denstedt JT, Trelford CB, Li EA, Hutnik CML. Differential effects of dexamethasone and indomethacin on tenon's capsule fibroblasts: Implications for glaucoma surgery. Exp Eye Res. 2019;182:65-73. DOI: 10.1016/j.exer.2019.03.015. PMID: 30910611
    7. Armstrong JJ, Welk BK, Reid JNS, Kansal V, Hutnik CML. Secondary surgical intervention after primary glaucoma filtration surgery: An ontario population-based study. Can J Ophthalmol. 2019;54(2):212-22. DOI: 10.1016/j.jcjo.2018.04.004. PMID: 30975345
    8. Asadi F, Dhanvantari S. Plasticity in the glucagon interactome reveals novel proteins that regulate glucagon secretion in α-TC1-6 cells. Front Endocrinol. 2019;10 JAN. DOI: 10.3389/fendo.2018.00792
    9. Asiry S, Ang L-C. Laboratory safety: Chemical and physical hazards; 2019. 243 p. DOI: 10.1007/978-1-4939-8935-5_21. PMID: 30539449
    10. Avino M, Ng GT, He Y, Renaud MS, Jones BR, Poon AFY.  Tree shape-based approaches for the comparative study of cophylogeny. Ecol Evol. 2019 May 29;9(12):6756-6771. doi: 10.1002/ece3.5185. eCollection 2019 Jun.  PMID: 31312429
    11. Avino MPoon AFY. Detecting Amino Acid Coevolution with Bayesian Graphical Models; 2019. 105 p. DOI: 10.1007/978-1-4939-8736-8_6. PMID: 30298394
    12. Bateman EA, Gob A, Chin-Yee I, MacKenzie HM.  Reducing waste: a guidelines-based approach to reducing inappropriate vitamin D and TSH testing in the inpatient rehabilitation setting.BMJ Open Qual. 2019 Oct 25;8(4):e000674. doi: 10.1136/bmjoq-2019-000674. eCollection 2019.  PMID: 31750404
    13. Bend EG, Aref-Eshghi E, Everman DB, Rogers RC, Cathey SS, Prijoles EJ, Lyons MJ, Davis H, Clarkson K, Gripp KW, Li D, Bhoj E, Zackai E, Mark P, Hakonarson H, Demmer LA, Levy MA, Kerkhof J, Stuart A, Rodenhiser D, Friez MJ, Stevenson RE, Schwartz CE, Sadikovic B. Gene domain-specific DNA methylation episignatures highlight distinct molecular entities of ADNP syndrome. Clin Epigenetics. 2019 Apr 27;11(1):64. DOI: 10.1186/s13148-019-0658-5. PMID: 31029150
    14. Bhattacharjee RN, Ruthirakanthan A, Sun Q, Richard-Mohamed M, Luke S, Jiang L, Aquil S, Sharma H, Tun-Abraham ME, Alharbi B, Haig A, Sener A, Luke PPW.  Subnormothermic Oxygenated Perfusion Optimally Preserves Donor Kidneys Ex Vivo. Kidney Int Rep. 2019 May 22;4(9):1323-1333. doi: 10.1016/j.ekir.2019.05.013. eCollection 2019 Sep. PMID: 31517151 [PubMed] Free PMC Article
    15. Bienz MN, Hsia C, Waye JS, Bode M, Solh Z. A novel human β-globin gene variant [hb london-ontario, HBB: C.332T>G] is associated with transfusion-dependent anemia in a patient with a hemoglobin electrophoresis pattern consistent with β-thalassemia trait. Hemoglobin. 2019 Mar;43(2):129-131. doi: 10.1080/03630269.2019.1619575. Epub 2019 Jun 27. PubMed PMID: 31246535. 
    16. Biswas S, Chen S, Liang G, Feng B, Cai L, Khan ZA, Chakrabarti S. Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes.  Front Endocrinol (Lausanne). 2019 Dec 18;10:887. doi: 10.3389/fendo.2019.00887. eCollection 2019.  PMID: 31920992
    17. Biswas S, Chakrabarti S. Increased Extracellular Matrix Protein Production in Chronic Diabetic Complications: Implications of Non-Coding RNAs. 2019 Mar 22;5(1). pii: E30. doi: 10.3390/ncrna5010030. PMID: 30909482
    18. Biswas S, Sarabusky M, Chakrabarti S.  Diabetic Retinopathy, lncRNAs, and Inflammation: A Dynamic, Interconnected Network  J Clin Med. 2019 Jul 14;8(7). pii: E1033. doi: 10.3390/jcm807103  PMID: 31337130
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    96. Nmezi B, Giorgio E, Raininko R, Lehman A, Spielmann M, Koenig MK, Adejumo R, Knight M, Gavrilova R, Alturkustani M, Sharma M, Hammond R, Gahl WA, Toro C, Brusco A, Padiath QS. Genomic deletions upstream of lamin B1 lead to atypical autosomal dominant leukodystrophy. Neurol Genet. 2019 Jan 24;5(1):e305. DOI: 10.1212/NXG.0000000000000305. PMID: 30842973
    97. Olabode AS, Avino M, Ng GT, Abu-Sardanah F, Dick DW, Poon AFY. Evidence for a recombinant origin of HIV-1 Group M from genomic variation. Virus Evol. 2019 Jan 22;5(1):vey039. DOI: 10.1093/ve/vey039. PMID: 30687518
    98. Palma DA, Nguyen TK, Louie AV, Malthaner R, Fortin D, Rodrigues GB, Yaremko B, Laba J, Kwan K, Gaede S, Lee T, Ward A, Warner A, Inculet R. Measuring the integration of stereotactic ablative radiotherapy plus surgery for early-stage non-small cell lung cancer: A phase 2 clinical trial. JAMA Oncol. 2019. DOI: 10.1001/jamaoncol.2018.6993. SLUG
    99. Palmer J, Poon AFY.  Phylogenetic measures of indel rate variation among the HIV-1 group M subtypes.  Virus Evol. 2019 Jul 21;5(2):vez022. doi: 10.1093/ve/vez022. eCollection 2019 Jul.  PMID: 31341641
    100. Patriquin CJ, Kiss T, Caplan S, Chin-Yee I, Grewal K, Grossman J, Larratt L, Marceau D, Nevill T, Sutherland DR, Wells RA, Leber B. How we treat paroxysmal nocturnal hemoglobinuria: A consensus statement of the canadian PNH network and review of the national registry. Eur J Haematol. 2019;102(1):36-52. DOI: 10.1111/ejh.13176. PMID: 30242915
    101. Plantinga P, Rahman S, Rizkalla K, Shepherd JG, Phua CW.  Splenic Angiosarcoma with Bone Marrow Involvement Initially Diagnosed as Systemic Mastocytosis: A Case Report.  Cureus. 2019 Sep 30;11(9):e5804. doi: 10.7759/cureus.5804.  PMID: 31720194
    102. Poon AFY, Ndashimye E, Avino M, Gibson R, Kityo C, Kyeyune F, Nankya I, Quiñones-Mateu ME, ARTS EJ, Paton NI, Walker S, Hoppe A, de Wit TFR, Sigaloff KCE, Hamers R, Boender TS, Boerma RS, Ondoa P, Nijboer M, Kroeze S, Inzaule S, Mutuluuza CK, Akanmu AS. First-line HIV treatment failures in non-B subtypes and recombinants: A cross-sectional analysis of multiple populations in uganda. AIDS Res Ther. 2019;16(1). DOI: 10.1186/s12981-019-0218-2. PMID: 30670037
    103. Qian J, Chen X, Chen X, Sun C, Jiang Y, Qian Y, Zhang Y, Khan Z, Zhou J, Liang G, Zheng C. Kaempferol reduces K63-linked polyubiquitination to inhibit nuclear factor-κB and inflammatory responses in acute lung injury in mice. Toxicol Lett. 2019;306:53-60. DOI: 10.1016/j.toxlet.2019.02.005.
    104. Quansah R, Bend JR, Armah FA, Bonney F, Aseidu J, Yawson DO, Adu MO, Luginaah I, Essumang DK, Abdul-Rahaman A, Cobbina S, Iddi S, Tersigni M, Afful S, Osei-Fosu P, Nketiah-Amponsah E.  Respiratory and non-respiratory symptoms associated with pesticide management practices among farmers in Ghana's most important vegetable hub.  Environ Monit Assess. 2019 Nov 4;191(12):716. doi: 10.1007/s10661-019-7898-x. PMID: 31686222
    105. Reid J, Wehrli B, Sowerby LJ. Spindle Cell Lipomas of the Respiratory Tract: A Case Report and Comprehensive Literature Review. Ann Otol Rhinol Laryngol. 2019 Nov;128(11):1086-1091. doi: 10.1177/0003489419862577. Epub 2019 Jul 10. Review.  PMID: 31291740
    106. Robinson LJ, Lu M, Elsayed S, Joy TR. Bilateral adrenal histoplasmosis manifesting as primary adrenal insufficiency. CMAJ. 2019 Nov 4;191(44):E1217-E1221. doi: 10.1503/cmaj.190710. PMID: 31685665
    107. Rodriguez Cuellar CI, García de la Puente S, Hernández Moraria J, Bojórquez Ochoa A, Filler G, Zaltzman Grishevich S. High depression rates among pediatric renal replacement therapy patients: A cross-sectional study.  Pediatr Transplant. 2019 Oct 4:e13591. doi: 10.1111/petr.13591. [Epub ahead of print]  PMID:  31583800
    108. Rodriguez Cuellar CI, Wang PZT, Freundlich M, Filler G. Educational review: Role of the pediatric nephrologists in the work-up and management of kidney stones. Pediatr Nephrol. 2019. DOI: 10.1007/s00467-018-4179-9
    109. Rosen LE, Fogarty U, O’Keeffe JJ, Olea Popelka F. Monitoring European badger (Meles meles) reproduction under evolving bovine tuberculosis management in Ireland. l. Eur J Wildl Res (2019) 65: 97. https://doi.org/10.1007/s10344-019-1340-0
    110. Ruicci KM, Plantinga PPinto NKhan MIStecho WDhaliwal SSYoo JFung KMacNeil DMymryk JSBarrett JWHowlett CJNichols AC. Disruption of the RICTOR/mTORC2 complex enhances the response of head and neck squamous cell carcinoma cells to PI3K inhibition. Mol Oncol. 2019 Aug 8. doi: 10.1002/1878-0261.12558. [Epub ahead of print]. PMID: 31393061
    111. Sadikovic B, Aref-Eshghi E, Levy MA, Rodenhiser D. DNA methylation signatures in mendelian developmental disorders as a diagnostic bridge between genotype and phenotype. Epigenomics. 2019 Mar 15. DOI: 10.2217/epi-2018-0192. PMID: 30875234
    112. Samuel SM, Dart A, Filler G, Bitzan M, Pinsk M, Mammen C, Nettel-Aguirre A, Perinpanayagam MA, Takano T, Chanchlani R, Zappitelli M; other members of the Canadian Childhood Nephrotic Syndrome Project Team. The Canadian childhood nephrotic syndrome (CHILDNEPH) study: report on mid-study feasibility, recruitment and main measures. BMC Nephrol. 2019 May 14;20(1):159. DOI: 10.1186/s12882-019-1320-3. PMID: 31088399
    113. Shrestha Palikhe N, Bosonea A-M, Laratta C, Gandhi VD, Nahirney D, Hillaby A, Bowen M, Bhutani M, Mayers I, Cameron L, Vliagoftis H. Stability of peripheral blood immune markers in patients with asthma. Allergy Asthma Clin Immunol. 2019;15(1). DOI: 10.1186/s13223-019-0343-4.
    114. So T, Sahovaler A, Nichols A, Fung K, Yoo J, Weir MM, MacNeil SD. Utility of clinical features with fine needle aspiration biopsy for diagnosis of Warthin tumor. J Otolaryngol Head Neck Surg. 2019 Aug 29;48(1):41. doi: 10.1186/s40463-019-0366-3.  PMID: 31464652
    115. Spence T, Stickle N, Yu C, Chow H, Feilotter H, Lo B, McCready E, Sadikovic B, Siu LL, Bedard PL, Stockley TL.  Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study. Curr Oncol. 2019 Dec;26(6):e717-e732. doi: 10.3747/co.26.5379. Epub 2019 Dec 1.  PMID: 31896942
    116. Spratt DE, Barber KR, Marlatt NM, Ngo V, Macklin JA, Xiao Y, Konermann L, Duennwald ML, Shaw GS. A subset of calcium-binding S100 proteins show preferential heterodimerization. FEBS J. 2019 May;286(10):1859-1876. doi: 10.1111/febs.14775. PMID: 30719832
    117. Staudt MD, Langdon KD, Hammond RR, Lownie, SP.  Incisional seeding of metastatic squamous cell carcinoma following carotid endarterectomy: An unusual case of an unknown primary cancer presenting as a presumed neck abscess.  Oper Neurosurg (Hagerstown). 2019 Aug 1;17(2):202-207. DOI: 10.1093/ons/opy335.  PMID:30418629
    118. Sullivan R, Randhawa VK, Stokes A, Wu D, Lalonde T, Kiaii B, Luyt L, Wisenberg G, Dhanvantari S. Dynamics of the Ghrelin/Growth Hormone Secretagogue Receptor System in the Human Heart Before and After Cardiac Transplantation. J Endocr Soc. 2019 Feb 14;3(4):748-762. DOI: 10.1210/js.2018-00393.
    119. Sung B, Su Y, Jiang J, Mcleod P, Liu W, Haig A, Green DR, Zhang ZX, Jevnikar AM.  Loss of receptor interacting protein kinases 3 and caspase-8 augments intrinsic apoptosis in tubular epithelial cell and promote kidney ischaemia-reperfusion injury.  Nephrology (Carlton). 2019 Jun;24(6):661-669. doi: 10.1111/nep.13487. Epub 2019 Apr 29.  PMID: 30175514
    120. Sy J, Ang L-C. Microtomy: Cutting formalin-fixed, paraffin-embedded sections; 2019. 269 p. DOI: 10.1007/978-1-4939-8935-5_23. PMID: 30539451
    121. Tadros M, Cabrera A, Matukas LM, Muller M. Evaluation of Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometry and ClinPro Tools as a Rapid Tool for Typing Streptococcus pyogenes.  Open Forum Infect Dis. 2019 Oct 11;6(11):ofz441. doi: 10.1093/ofid/ofz441. eCollection 2019 Nov. PMID: 31700941
    122. Tarnopolsky MA, Sundaram ANE, Provias J, Brady L, Sadikovic B (2019) CPEO - Like mitochondrial myopathy associated with m.8340G>A mutation. Mitochondrion 46: 69-72. DOI: 10.1016/j.mito.2018.02.008   PMID: 29501485
    123. Taylor RG, Alyamany B, Pandey S, Kertesz A, Ang LC, Finger E.  Looking Glass Syndromes: Two Sides of the Same Gene. Can J Neurol Sci. 2019 Jan;46(1):115-120. doi: 10.1017/cjn.2018.354. PMID: 30688199
    124. Tellios N, Feng M, Chen N, Liu H, Tellios V, Wang M, Li X, Chang C, Hutnik C. Mechanical stretch upregulates connexin43 in human trabecular meshwork cells. Clin Exp Ophthalmol. Epub 2019 Feb 28. DOI: 10.1111/ceo.13492. PMID: 30816600
    125. Teng X, Ji C, Zhong H, Zheng D, Ni R, Hill DJ, Xiong S, Fan G, Greer PA, Shen Z, Peng T. Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis. Diabetologia. 2019. DOI: 10.1007/s00125-019-4828-y
    126. Thomas AA, Biswas S, Feng B, Chen S, Gonder J, Chakrabarti S. lncRNA H19 prevents endothelial–mesenchymal transition in diabetic retinopathy. Diabetologia. 2019;62(3):517-30. DOI: 10.1007/s00125-018-4797-6. PMID: 30612136
    127. Thwaites MJ, Cecchini MJ, Passos DT, Zakirova K, Dick FA. Context dependent roles for RB-E2F transcriptional regulation in tumor suppression. PLoS One. 2019 Jan 31;14(1):e0203577. doi: 10.1371/journal.pone.0203577. eCollection 2019. PMID: 30703085
    128. Tsoi VK, Bhayana V, Bombassaro AM, Tirona R, Kittanakom S. Falsely elevated vancomycin concentration in a patient not receiving vancomycin. Pharmacotherapy 2019;39(7):778-782
    129. Vilos AG, Zhu C, Abu-Rafea B, Ettler HC, Weir MM, Vilos GA.  Uterine Tumors Resembling Ovarian Sex Cord Tumors Identified at Resectoscopic Endometrial Ablation: Report of 2 Cases.  J Minim Invasive Gynecol. 2019 Jan;26(1):105-109. doi: 10.1016/j.jmig.2018.04.013. Epub 2018 Apr 24.  PMID: 29702269
    130. Vu K, Payne MWC, Hunter SW, Viana R. Risk Factors for Falls in Individuals With Lower Extremity Amputations During the Pre-Prosthetic Phase: A Retrospective Cohort Study. PM R. 2019 Aug;11(8):828-833. doi: 10.1002/pmrj.12046. Epub 2019 Apr 1. PMID: 30934158
    131. Wertheim JO, Chato C, Poon AFY. Comparative analysis of HIV sequences in real time for public health. Curr Opin HIV AIDS. 2019 Mar 5. DOI: 10.1097/COH.0000000000000539. PMID: 30882486
    132. White I, Smith S, Rizkalla K, Davies E. Unexpected Gallbladder Metastasis of Clear Cell Renal Carcinoma. Clin Pathol. 2019 Jul 22;12:2632010X19861112. doi: 10.1177/2632010X19861112. eCollection 2019 Jan-Dec. PMID: 31384752
    133. Williams KC, Cepeda MA, Javed S, Searle K, Parkins KM, Makela AV, Hamilton AM, Soukhtehzari S, Kim Y, Tuck AB, Ronald JA, Foster PJ, Chambers AF, Leong HS.  Invadopodia are chemosensing protrusions that guide cancer cell extravasation to promote brain tropism in metastasis.  Oncogene. 2019 May;38(19):3598-3615. doi: 10.1038/s41388-018-0667-4. Epub 2019 Jan 16.  PMID: 30651600
    134. Wong F, Al Ibrahim B, Walsh J, Qumosani K. Infliximab-induced autoimmune hepatitis requiring liver transplantation.  Clin Case Rep. 2019 Sep 27;7(11):2135-2139. doi: 10.1002/ccr3.2456. eCollection 2019 Nov. PMID: 31788265
    135. Wylie L, McConkey S. Insiders’ insight: Discrimination against indigenous peoples through the eyes of health care professionals. J Racial Ethn Health Disparities. 2019;6(1):37-45. DOI: 10.1007/s40615-018-0495-9. PMID: 29736617
    136. Xu Q, House AA, Leckie S, Gunaratnam L, Luke PP, Jevnikar AM.Patients with immunological diseases or on peritoneal dialysis are prone to false positive flow cytometry crossmatch.  Hum Immunol. 2019 Jul;80(7):487-492. doi: 10.1016/j.humimm.2019.03.015. Epub 2019 Mar 20.  PMID: 30904438
    137. Yuan Y, Chen Y, Peng T, Li L, Zhu W, Liu F, Liu S, An X, Luo R, Cheng J, Liu J, Lu Y.  Mitochondrial ROS-induced lysosomal dysfunction impairs autophagic flux and contributes to M1 macrophage polarization in a diabetic condition   Clin Sci (Lond). 2019 Aug 14;133(15):1759-1777. doi: 10.1042/CS20190672. Print 2019 Aug 15.  PMID: 31383716
    138. Yuan Y, Zhu L, Li L, Liu J, Chen Y, Cheng J, Peng T, Lu Y. S-Sulfhydration of SIRT3 by Hydrogen Sulfide Attenuates Mitochondrial Dysfunction in Cisplatin-Induced Acute Kidney Injury.  Antioxid Redox Signal. 2019 Dec;31(17):1302-1319. doi: 10.1089/ars.2019.7728. Epub 2019 Jul 17.  PMID:   31218880
    139. Zhang M, Gao D, Shi Y, Wang Y, Joshi R, Yu Q, Liu D, Alotaibi F, Zhang Y, Wang H, Li Q, Zhang ZX, Koropatnick J, Min W.  miR-149-3p reverses CD8+ T-cell exhaustion by reducing inhibitory receptors and promoting cytokine secretion in breast cancer cells. Open Biol. 2019 Oct 31;9(10):190061. doi: 10.1098/rsob.190061. Epub 2019 Oct 9.  PMID: 31594465
    140. Zhanel GG, Adam HJ, Baxter MR, Fuller J, Nichol KA, Denisuik AJ, Golden AR, Hink R, Lagacé-Wiens PRS, Walkty A, Mulvey MR, Schweizer F, Bay D, Hoban DJ, Karlowsky JA; Canadian Antimicrobial Resistance Alliance (CARA) and CANWARD. 42936 pathogens from Canadian hospitals: 10 years of results (2007-16) from the CANWARD surveillance study. J Antimicrob Chemother. 2019 Aug 1;74(Supplement_4):iv5-iv21. doi: 10.1093/jac/dkz283. PMID: 31505641
    141. Zhao D, Shun E, Ling F, Liu Q, Warsi A, Wang B, Zhou Q, Zhu C, Zheng H, Liu K, Zheng X.  Plk2 Regulated by miR-128 Induces Ischemia-Reperfusion Injury in Cardiac Cells.  Mol Ther Nucleic Acids. 2019 Nov 30;19:458-467. doi: 10.1016/j.omtn.2019.11.029.  PMID: 31902745
    142. Zheng D, Su Z, Zhang Y, Ni R, Fan GC, Robbins J, Song LS, Li J, Peng T. Calpain-2 promotes MKP-1 expression protecting cardiomyocytes in both in vitro and in vivo mouse models of doxorubicin-induced cardiotoxicity. Arch Toxicol. Epub 2019 Feb 27. DOI: 10.1007/s00204-019-02405-w. PMID: 30810770
    143. Zheng D, Zhang Y, Zheng M, Cao T, Wang G, Zhang L, Ni R, Brockman J, Zhong H, Fan G-C, Peng T.  Nicotinamide riboside promotes autolysosome clearance in preventing doxorubicin-induced cardiotoxicity. Clin Sci (Lond). 2019 Jul 15;133(13):1505-1521. doi: 10.1042/CS20181022. Print 2019 Jul 15. PMID:31266854
    144. Zhu C, Su Y, Juriasingani S, Zheng H, Veramkovich V, Jiang J, Sener A, Whiteman M, Lacefield J, Nagpal D, Alotaibi F, Liu K, Zheng X.  Supplementing preservation solution with mitochondria-targeted H2S donor AP39 protects cardiac grafts from prolonged cold ischemia reperfusion injury in heart transplantation. Am J Transplant. 2019 Nov; 19(11):3139-3148. doi: 10.1111/ajt.15539. Epub 2019 Sep 3. PMID: 31338943
    145. Zibrowski E, Shepherd L, Booth R, Sedig K, Gibson C. A Qualitative Study of the Theory Behind the Chairs: Balancing Lean-Accelerated Patient Flow With the Need for Privacy and Confidentiality in an Emergency Medicine Setting. JMIR Hum Factors. 2019 Feb 6;6(1):e11714. DOI: 10.2196/11714. PMID: 30724743

2018 Publications

    1. Abdelhameed M, Martir DR, Chen S, Xu WZ, Oyeneye OO, Chakrabarti S, Zysman-Colman E, Charpentier PA. Tuning the Optical Properties of Silicon Quantum Dots via Surface Functionalization with Conjugated Aromatic Fluorophores. Sci Rep. 2018 Feb 14;8(1):3050. DOI: 10.1038/s41598-018-21181-8. PMID: 29445234
    2. Adams P, Howlett C, Xenocostas A, Chakrabarti S. Sex-specific analysis post-liver transplantation in hemochromatosis with aplastic anemia and hepatocellular carcinoma. Hepatol Commun. 2017 Nov 11;2(1):13-15. DOI: 10.1002/hep4.1122. eCollection 2018 Jan. PMID: 29404507.
    3. Adeyanju K, Bend JR, Rieder MJ, Dekaban GA. HIV-1 Tat expression and sulphamethoxazole hydroxylamine mediated oxidative stress alter the disulfide proteome in Jurkat T cells. Virology Journal, In Press (VIRJ-D-18-00011R2).
    4. Al-Judaibi B, Hernandez-Alejandro R, Herath C, Chakrabarti S, Katherine Dokus M, Marotta P, Alghanem M. IgG4 status in explanted livers does not affect the outcome of primary sclerosing cholangitis (PSC) after liver transplant. Hepat Mon. 2018;18(7) DOI: 10.5812/hepatmon.66037
    5. Ampadu O J, Mugwaneza A R, Chakrabarti S, Long S.  Molecular mechanisms and genetic regulation in atherosclerosis. Int. J.  card. heart and vasculature 2018; 21: 36–44.  doi: 10.1016/j.ijcha.2018.09.006
    6. Amtul Z, Hill DJ, Arany EJ, Cechetto DF. Altered Insulin/Insulin-Like Growth Factor Signaling in a Comorbid Rat model of Ischemia and β-Amyloid Toxicity.Sci Rep. 2018 Mar 23;8(1):5136. DOI: 10.1038/s41598-018-22985-4. PMID: 29572520.
    7. Amtul Z, Frías C, Randhawa J, Hill DJ, Arany EJ. Spatial Dynamics of Vascular and Biochemical Injury in Rat Hippocampus Following Striatal Injury and Aβ Toxicity. Mol Neurobiol. 2019 Apr;56(4):2714-2727. DOI: 10.1007/s12035-018-1225-3.
    8. Al-Judaibi B, Hernandez-Alejandro R, Herath C, Chakrabarti S, Katherine Dokus M, Marotta P, Alghanem M. IgG4 status in explanted livers does not affect the outcome of primary sclerosing cholangitis (PSC) after liver transplant. Hepat Mon. 2018;18(7) DOI: 10.5812/hepatmon.66037
    9. Arany EJ, Waseem M, Strutt BJ, Chamson-Reig A, Bernardo A, Eng E, Hill DJ.  Direct comparison of the abilities of bone marrow mesenchymal versus hematopoietic stem cellsto reverse hyperglycemia in diabetic NOD.SCID mice.  Islets. 2018;10(4):137-150. DOI: 10.1080/19382014.2018.1480285. Epub 2018 Aug 15.  PMID: 30110202
    10. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B. The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance.  Epigenetics. 2017;12(11):923-933. DOI: 10.1080/15592294.2017.1381807. Epub 2017 Nov 7.  PMID: 28933623
    11. Aref-Eshghi E, Bend EG, Hood RL, Schenkel LC, Carere DA, Chakrabarti R, Nagamani SCS, Cheung SW, Campeau PM, Prasad C, Siu VM, Brady L, Tarnopolsky MA, Callen DJ, Innes AM, White SM, Meschino WS, Shuen AY, Paré G, Bulman DE, Ainsworth PJ, Lin H, Rodenhiser DI, Hennekam RC, Boycott KM, Schwartz CE, Sadikovic B. BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes. Nat Commun. 2018 Nov 20;9(1):4885. DOI: 10.1038/s41467-018-07193-y. PMID: 30459321 PMCID: PMC6244416
    12. Aref-Eshghi E, Rodenhiser DI, Schenkel LC, Lin H, Skinner C, Ainsworth P, Pare G, Hood RL, Bulman DE, Kernohan KD, Care4Rare Canada Consortium, Boycott KM, Campeau PM, Schwartz C, Sadikovic B. Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes. Am J Hum Genet. 2018 Jan 4;102(1):156-174. DOI: 10.1016/j.ajhg.2017.12.008. PMID: 29304373.
    13. Aref-Eshghi E, Schenkel LC, Ainsworth P, Lin H, Rodenhiser DI, Cutz JC, Sadikovic B. Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues. Front Oncol. 2018 Apr 23;8:100. DOI: 10.3389/fonc.2018.00100. eCollection 2018. PMID: 29740534.
    14. Barber C, Hammond R, Gula L, Tithecott G, Chahine S.  In Search of Black Swans: Identifying Students at Risk of Failing Licensing Examinations.  Acad Med. 2018 Mar;93(3):478-485. DOI: 10.1097/ACM.0000000000001938  PMID: 28953566
    15. Bauman G, Martin P, Thiessen JD, Taylor R, Moussa M, Gaed M, Rachinsky I, Kassam Z, Chin J, Pautler S, Lee TY, Valliant JF, Ward A. [18F]-DCFPyL positron emission Tomography/Magnetic resonance imaging for localization of dominant intraprostatic foci: First experience. Eur Urol Focus. 2018;4(5):702-6. DOI: 10.1016/j.euf.2016.10.002. PMID: 28753797
    16. Bhattacharjee RN, Richard-Mohamed M, Sun Q, Haig A, Aboalsamh G, Barrett P, Mayer R, Alhasan I, Pineda-Solis K, Jiang L, Alharbi H, Saha M, Patterson E, Sener A, Cepinskas G, Jevnikar AM, Luke PPW. CORM-401 reduces ischemia reperfusion injury in an ex vivo renal porcine model of the donation after circulatory death. Transplantation. 2018;102(7):1066-74. DOI: 10.1097/TP.0000000000002201. PMID: 29677080
    17. Biswas S, Feng B, Thomas A, Chen S, Aref-Eshghi E, Sadikovic BChakrabarti S.  Endothelin-1 regulation is entangled in a complex web of epigenetic mechanisms in diabetes.  Physiol Res. 2018 Jun 27;67(Supplementum 1):S115-S125. PMID: 29947532
    18. Biswas S, Thomas A , Biao F, Chen S , Gonder J, Chakrabarti S.  Role of Long Non-Coding RNA MALAT1 in the Pathogenesis of Diabetic Retinopathy.  Canad. J. Diab 41(suppl) 159A, 2017.
    19. Biswas S, Thomas A, Feng B, Chen S, E Aref-Eshghi , Gonder J, Sadikovic B, Chakrabarti S. MALAT1 and HOTAIR: Key Epigenetic Regulators in Diabetic Retinopathy.  Diabetes 66 (suppl. 1), https://plan.core-apps.com/tristar_ada18/abstract/807d2f9885450670bb994661e367b251
    20. Biswas S, Thomas AA, Chakrabarti S. LncRNAs: Proverbial Genomic “Junk” or Key Epigenetic Regulators During Cardiac Fibrosis in Diabetes?. Front Cardiovasc Med. 2018 Apr 4;5:28. DOI: 10.3389/fcvm.2018.00028. eCollection 2018. PMID: 29670886.
    21. Biswas S, Thomas AA, Chen S, Aref-Eshghi, Feng B, Gonder J, Sadikovic B, Chakrabarti S. MALAT1: An Epigenetic Regulator of Inflammation in Diabetic Retinopathy. Sci Rep. April 2018;8(1):6526. DOI:10.1038/s41598-018-24907-w. PMID: 29695738.
    22. Booth RA, McCudden CR, Yang L et at. Candidate recommendations for protein electrophoresis reporting from the Canadian Society of Clinical Chemists Monoclonal Gammopathy Working Group. Clin Biochem. 2018; 51:10-20.
    23. Brady L, Sadikovic B, Rupar CA, Tarnopolsky MA. Complete elimination of a pathogenic homoplasmic mtDNA mutation in one generation. Mitochondrion. 2018 Feb 1. pii: S1567-7249(17)30328-8. DOI: 10.1016/j.mito.2018.01.010. [Epub ahead of print]. PMID: 29408632.
    24. Brichacek M, Naeem A, Filler G, Hammond R, Yazdani A, Ranger A.  Congenital Calvarial Hemangioma.  J Craniofac Surg. 2018 May 8. DOI: 10.1097/SCS.0000000000004613. [Epub ahead of print]  PMID: 29742579
    25. Broeke NC, Peterson J, Lee J, Martin PA, Farag A, Gomez JA, Moussa M, Gaed M, Chin J, Pautler SE, Ward A, Bauman G, Bartha R, Scholl TJ. Characterization of clinical human prostate cancer lesions using 3.0-T sodium MRI registered to Gleason-graded whole-mount histopathology. J Magn Reson Imaging. 2018 Nov 14. [Epub ahead of print] PMID: 30430700 DOI: 10.1002/jmri.26336
    26. Brooks SD, Hileman SM, Chantler PD, Milde SA, Lemaster KA, Frisbee SJ, Shoemaker JK, Jackson DN, Frisbee JC. Protection from vascular dysfunction in female rats with chronic stress and depressive symptoms. Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1070-H1084. DOI: 10.1152/ajpheart.00647.2017. Epub 2018 Feb 16. PMID:29451821.
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    102. Liu Y, Sethi NS, Hinoue T, Schneider BG, Cherniack AD, Sanchez-Vega F, Seoane JA, Farshidfar F, Bowlby R, Islam M, Kim J, Chatila W, Akbani R, Kanchi RS, Rabkin CS, Willis JE, Wang KK, McCall SJ, Mishra L, Ojesina AI, Bullman S, Pedamallu CS, Lazar AJ, Sakai R, Cancer Genome Atlas Research Network., Thorsson V, Bass AJ, Laird PW.  Comparative Molecular Analysis of Gastrointestinal Adenocarcinomas (Parfitt, J).  Cancer Cell. 2018 Apr 9;33(4):721-735.e8. DOI: 10.1016/j.ccell.2018.03.010. Epub 2018 Apr 2.  PMID: 29622466
    103. MacLean Scott E, Solomon LA, Davidson C, Storie J, Palikhe NS, Cameron L.  Activation of Th2 cells downregulates CRTh2 through an NFAT1 mediated mechanism.  PLoS One. 2018 Jul 3;13(7):e0199156. DOI: 10.1371/journal.pone.0199156. eCollection 2018.  PMID: 29969451
    104. Mataseje LF, Boyd DA, Fuller J, Haldane D, Hoang L, Lefebvre B, Melano RG, Poutanen S, Van Caeseele P, Mulvey MR. Characterization of OXA-48-like carbapenemase producers in Canada, 2011-14. J Antimicrob Chemother. 2017 Dec 18. doi: 10.1093/jac/dkx462. [Epub ahead of print]. PMID: 29272439.
    105. Medeiros M, Lumini J, Stern N, Castañeda-Hernández G, Filler G. Generic immunosuppressants. Pediatr Nephrol. 2018;33(7):1123-31. DOI: 10.1007/s00467-017-3735-z
    106. Morrison MD, Jackson-Boeters L, Khan ZA, Shimizu MS, Franklin JH, Fung K, Yoo. JHJ, Darling MR. Identifying Candidate Biomarkers for Pleomorphic Adenoma: A Case-Control Study. Head Neck Pathol. 2018 Aug 17. DOI: 10.1007/s12105-018-0959-6. [Epub ahead of print] PubMed PMID: 30120721.
    107. Nahlawi L, Goncalves C, Imani F, Gaed M, Gomez JA, Moussa M, Gibson E, Fenster A, Ward A, Abolmaesumi P, Shatkay H, Mousavi P. Stochastic modeling of temporal enhanced ultrasound: Impact of temporal properties on prostate cancer characterization. IEEE Trans Biomed Eng. 2018;65(8):1798-809. DOI: 10.1109/TBME.2017.2778007. PMID: 29989922
    108. Ndashimye E, Avino M, Kyeyune F, Nankya I, Gibson RM, Nabulime E, Poon AFY, Kityo C, Mugyenyi P, Quiñones-Mateu ME, Arts EJ. Absence of HIV-1 drug resistance mutations supports the use of dolutegravir in uganda. AIDS Res Hum Retroviruses. 2018;34(5):404-14. DOI: 10.1089/aid.2017.0205. PMID: 29353487
    109. Noonan MM, Dragan M, Mehta MM, Hess DA, Brackstone M, Tuck AB, Viswakarma N, Rana A, Babwah AV, Wondisford FE, Bhattacharya M. The matrix protein fibulin-3 promotes KISS1R induced triple negative breast cancer cell invasion. Oncotarget. 2018;9(53):30034-52. DOI: 10.18632/oncotarget.25682
    110. Osmond A, Ashok D, Francoeur CA, Miller M, Walsh JC. Is focal active colitis of greater clinical significance in pediatric patients? A retrospective review of 68 cases with clinical correlation. Hum Pathol, 2018 Jan 20. DOI: 10.1016/j.humpath.2018.01.012. PMID: 29360496.
    111. Pacheco I, Buzea C. Nanoparticle uptake by plants – beneficial or detrimental?, invited book chapter in Phytotoxicity of nanoparticles, Editors: M. Faisal, Q. Saquib, A. A. Alatar, A.z A. Al-Khedhairy, Springer Science & Business Media, 2018.
    112. Plouffe RA, Hammond R, Goldberg HA, Chahine S. What Matters from Admissions? Identifying Success and Risk Among Canadian Dental Students.  J Dent Educ. 2018 May;82(5):515-523. DOI: 10.21815/JDE.018.057.  PMID: 29717076
    113. Poon AFY, Prodger JL, Lynch BA, Lai J, Reynolds SJ, Kasule J, Capoferri AA, Lamers SL, Rodriguez CW, Bruno D, Porcella SF, Martens C, Quinn TC, Redd AD. Quantitation of the latent HIV-1 reservoir from the sequence diversity in viral outgrowth assays. Retrovirology. 2018;15(1) DOI: 10.1186/s12977-018-0426-1. PMID: 29976219
    114. Poon AFY, Dearlove BL. Quantifying the aftermath: Recent outbreaks among people who inject drugs and the utility of phylodynamics. J Infect Dis. 2018;217(12):1854-7. DOI: 10.1093/infdis/jiy132 PMID: 29546389
    115. Rakovitch E, Nofech-Mozes S, Hanna W, Sutradhar R, Gu S, Fong C, Tuck A, Youngson B, Miller N, Done SJ, Chang MC, Sengupta S, Elavathil L, Jani PA, Bonin M, Lalani N, Paszat L. Omitting radiation therapy after lumpectomy for pure DCIS does not reduce the risk of salvage mastectomy. Breast. 2018 Feb;37:181-186. DOI: 10.1016/j.breast.2017.07.002. Epub 2017 Aug 3. PMID: 28781102.
    116. Remington L, Isaacs A, Vickers D, Fuller J, and Smith S. Epidemiology of candidemia at a tertiary Canadian hospital 2004-2013. J. Assoc Med Microbiol Infect Dis. 2018 March 12;3.1:14-23.
    117. Ruicci KM, Meens J, Sun RX, Rizzo G, Pinto N, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Boutros PC, Ailles L, Nichols AC. A controlled trial of HNSCC patient-derived xenografts reveals broad efficacy of PI3Ka inhibition in controlling tumor growth. Int J Cancer. 2018 Nov 23. DOI: 10.1002/ijc.32009. [Epub ahead of print] PMID: 30468243
    118. Ruicci KM, Pinto N, Khan MI, Yoo J, Fung K, MacNeil D, Mymryk JS, Barrett JW, Nichols AC.  ERK-TSC2 signalling in constitutively-active HRAS mutant HNSCC cells promotes resistance to PI3K inhibition.  Oral Oncol. 2018 Sep;84:95-103. doi: 10.1016/j.oraloncology.2018.07.010.   PMID: 30115483
    119. Rutledge AB, McLeod N, Mehan N, Regan TW, Ainsworth P, Chong P, Doyle T, White M, Sanson-Fisher RW, Martin JM. A clinician-centred program for behaviour change in the optimal use of staging investigations for newly diagnosed prostate cancer. BJU Int. 2018 May;121 Suppl 3:22-27. DOI: 10.1111/bju.14144. Epub 2018 Feb 16.  PMID: 29359883.
    120. Schenkel LC, Aref-Eshghi E, Skinner C, Ainsworth P, Lin H, Paré G, Rodenhiser DI, Schwartz C, Sadikovic B. Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C. Clin Epigenetics. 2018 Feb 14;10:21. DOI: 10.1186/s13148-018-0453-8. eCollection 2018. PMID: 29456765.
    121. Silva PN, Chang HH, Arany EJ, Shukalyuk AI, Audet J, Kilkenny DM, Rocheleau JV. Fibroblast growth factor receptor 5 (FGFR5) is a co-receptor for FGFR1 that is up-regulated in beta-cells by cytokine-induced inflammation. J Biol Chem. 2018 Sep 14. pii: jbc.RA118.003036. DOI: 10.1074/jbc.RA118.003036. [Epub ahead of print] PMID: 30217817
    122. Singh SS, Pilkerton CS, Shrader CD Jr, Frisbee SJ. Subclinical atherosclerosis, cardiovascular health, and disease risk: is there a case for the Cardiovascular Health Index in the primary prevention population?  BMC Public Health. 2018 Apr 2;18(1):429. DOI: 10.1186/s12889-018-5263-6. PMID: 29609588.
    123. Singhsnaeh A, Ang LC. Intramedullary spinal cord metastatic plasmacytoid melanoma: Case report and literature review. J Med Assoc Thailand. 2018;101(7):993-6.
    124. Shi T, Shkrum MJ. A case report of sudden death from intracardiac leiomyomatosis. Am J Forensic Med Pathol. 2018;39(2):119-22. DOI: 10.1097/PAF.0000000000000377. PMID: 29351101
    125. Solis-Reyes S, Avino M, Poon A, Kari L. An open-source k-mer based machine learning tool for fast and accurate subtyping of HIV-1 genomes. PLoS ONE. 2018;13(11):e0206409. DOI: 10.1371/journal.pone.0206409. PMID: 30427878
    126. Solh Z, Brouwers M, Florez ID. Knowledge translation in transfusion medicine. Part 1: The basics and the frameworks. Transfusion. 2018 Jan 30. DOI: 10.1111/trf.14487. [Epub ahead of print]. PMID: 29383724.
    127. Solh Z, Brouwers M, Florez ID. Knowledge translation in transfusion medicine. Part 3: Interventions and tools. Transfusion. 2018 Apr 17. DOI: 10.1111/trf.14653. [Epub ahead of print]. PMID: 29667202.
    128. Staudt MD, Langdon KD, Hammond RR, Lownie SP. Incisional Seeding of Metastatic Squamous Cell Carcinoma Following Carotid Endarterectomy: An Unusual Case of an Unknown Primary Cancer Presenting as a Presumed Neck Abscess. Oper Neurosurg (Hagerstown). 2018 Nov 10. DOI: 10.1093/ons/opy335. PMID: 30418629
    129. Sullivan R, McGirr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L, Dhanvantari S.  Changes in the Cardiac GHSR1a-Ghrelin System Correlate With Myocardial Dysfunction in Diabetic Cardiomyopathy in Mice.  J Endocr Soc. 2017 Dec 28;2(2):178-189. DOI: 10.1210/js.2017-00433. eCollection 2018 Feb 1.  PMID: 29450407
    130. Tao A, Xu X, Kvietys P, Kao R, Martin C, Rui T. Experimental diabetes mellitus exacerbates ischemia/reperfusion-induced myocardial injury by promoting mitochondrial fission: Role of down-regulation of myocardial Sirt1 and subsequent Akt/Drp1 interaction. Int J Biochem Cell Biol. 2018;105:94-103. DOI: 10.1016/j.biocel.2018.10.011
    131. Tarnopolsky MA, Sundaram ANE, Provias J, Brady L, Sadikovic B. CPEO - Like mitochondrial myopathy associated with m.8340G>A mutation. Mitochondrion. 2018 Mar 6. pii: S1567-7249(17)30331-8. DOI:10.1016/j.mito.2018.02.008. [Epub ahead of print]. PMID: 29501485.
    132. Taylor R, Alyamany B, Pandey S, Kertesz A, Ang LC, Finger E.  Two Distinct Clinical Phenotypes in a Family with ALSP Caused by a Novel CSF-1R Mutation. (P2.176)  Neurology April 10, 2018; 90 (15 Supplement)
    133. Thomas AA, Feng B, Chakrabarti S. ANRIL regulates production of extracellular matrix proteins and vasoactive factors in diabetic complications. Am J Physiol Endocrinol Metab. 2018 Mar 1;314(3):E191-E200. DOI: 10.1152/ajpendo.00268.2017. Epub 2017 Nov 7. PMID: 29118015
    134. Tong J, Fitzmaurice PS, Moszczynska A, Rathitharan G, Ang LC, Meyer JH, Mizrahi R, Boileau I, Furukawa Y, McCluskey T, Sailasuta N, Kish SJ. Normal glutathione levels in autopsied brain of chronic users of heroin and of cocaine.  Drug Alcohol Depend. 2018 Jun 23;190:20-28. DOI: 10.1016/j.drugalcdep.2018.05.021. [Epub ahead of print]  PMID: 29960919
    135. Tsoi VK, Bhayana V, Bombassaro AM, Tirona R, Betchen D, Kittanakom S. Falsely Elevated Vancomycin Concentrations in a Patient Not Receiving Vancomycin. Canadian Journal of Hospital Pharmacy; 2018. p. 58.
    136. Volkening K, Keller BA, Leystra-Lantz C, Strong MJ. RNA and protein interactors with TDP-43 in human spinal-cord lysates in amyotrophic lateral sclerosis. J Proteome Res. 2018;17(4):1712-29. DOI: 10.1021/acs.jproteome.8b00126. PMID: 29513014
    137. Walsh JC, Padgett J, Weir MM, et al.  Comparing Perceptions of Pathology as a Medical Specialty between Canadian Pathologists and Pre-clinical Medical Students.  Med.Sci.Educ. (2018). DOI: 10.1007/s40670-018-0596-4
    138. Warners MJ, Ambarus CA, Bredenoord AJ, Verheij J, Lauwers GY, Walsh JC, Katzka DA, Nelson S, van Viegen T, Furuta GT, Gupta SK, Stitt L, Zou G, Parker CE, Shackelton LM, D Haens GR, Sandborn WJ, Dellon ES, Feagan BG, Collins MH, Jairath V, Pai RK. Reliability of Histologic Assessment in Patients with Eosinophilic Oesophagitis. PMID: 29460418.
    139. Wang PZT, Prasad C, Rodriguez Cuellar CI, Filler G. Nephrological and urological complications of homozygous c.974G>A (p.Arg325Gln) OSGEP mutations. Pediatr Nephrol. 2018;33(11):2201-4. DOI: 10.1007/s00467-018-4060-x
    140. Webster-Clark M, Jaeger B, Zhong Y, Filler G, Alvarez-Elias A, Franceschini N, Díaz-González de Ferris ME.  Low agreement between modified-Schwartz and CKD-EPI eGFR in young adults: a retrospectivelongitudinal cohort study.  BMC Nephrol. 2018 Aug 6;19(1):194. DOI: 10.1186/s12882-018-0995-1.  PMID: 30081844
    141. Yousef PG, Gabril MY. An update on the molecular pathology of urinary bladder tumors.Pathol Res Pract. 2018 Jan;214(1):1-6. DOI: 10.1016/j.prp.2017.11.003. Epub 2017 Nov 10. PMID: 29254798.
    142. Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. An aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation. Neuropathol Appl Neurobiol. Letter. 2018 Feb;44(2):240-243. DOI: 10.1111/nan.12404. PMID: 28403515.
    143. Zhang Y, Zhan X, Xiong J, Peng S, Huang W, Joshi R, Cai Y, Liu Y, Li R, Yuan K, Zhou N, Min W. Temperature-dependent cell death patterns induced by functionalized gold nanoparticle photothermal therapy in melanoma cells. Sci Rep. 2018;8(1) DOI: 10.1038/s41598-018-26978-1.
    144. Zhang Y, Wang Z, Huang Y, Ying M, Wang Y, Xiong J, Liu Q, Cao F, Joshi R, Liu Y, Xu D, Zhang M, Yuan K, Zhou N, Koropatnick J, Min W. TdIF1: A putative oncogene in NSCLC tumor progression. Signal Transduct Target Ther. 2018;3(1) DOI: 10.1038/s41392-018-0030-9
    145. Zhang Y, Zhan X, Peng S, Cai Y, Zhang YS, Liu Y, Wang Z, Yu Y, Wang Y, Shi Q, Zeng X, Yuan K, Zhou N, Joshi R, Zhang M, Zhang Z, Min W. Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem. Nanomed Nanotechnol Biol Med. 2018;14(5):1679-93. DOI: 10.1016/j.nano.2018.04.010. PMID: 29684526
    146. Zhang Y, Fu J, Shi Y, Peng S, Cai Y, Zhan X, Song N, Liu Y, Wang Z, Yu Y, Wang Y, Shi Q, Fu Y, Yuan K, Zhou N, Joshi R, Ichim TE, Min W. A new cancer immunotherapy via simultaneous DC-mobilization and DC-targeted IDO gene silencing using an immune-stimulatory nanosystem. Int J Cancer. 2018;143(8):2039-52. DOI: 10.1002/ijc.31588. PMID: 29752722
    147. Zhao Y, Zurawel AA, Jenkins NP, Duennwald ML, Cheng C, Kettenbach AN, Supattapone S. Comparative analysis of mutant huntingtin binding partners in yeast species. Sci Rep. 2018;8(1) DOI: 10.1038/s41598-018-27900-5. PMID: 29934597
    148. Zhao X, Sehgal M, Hou ZF, Cheng JJ, Shu SN, Wu S, Guo F, Le Marchand SJ, Lin HX, Chang J, and Guo JT. Identification of residues controlling restriction versus enhancing activities of IFITM proteins on the entry of human coronaviruses. Journal of Virology, 2018, Feb 26;92(6). DOI: 10.1128/JVI.01535-17. PMID:29263263.
    149. Zhou H and Fuller J. Recurrent Echinocandin-resistant Candida glabrata candidemia following prolonged micafungin treatment for multiple intra-abdominal abscesses: A case report. J. Assoc Med Microbiol Infect Dis. 2018 Apr 17;3.1:52-55.
    150. Zhuge W, Chen R, Guo G, Dong X, Khan Z, Sun X, Dai X, Chen X, Bao M, Shen X, Liang G. Costunolide specifically binds and inhibits thioredoxin reductase 1 to induce apoptosis in colon cancer. Cancer Lett. 2018 Jan 1;412:46-58. DOI: 10.1016/j.canlet.2017.10.006. Epub 2017 Oct 13. PMID: 29037867.
    151. Žigman T, Petković Ramadža D, Lušić M, Zekušić M, Ninković D, Gardijan D, Potočki K, Omerza L, Beljan L, Žarković K, Kerkhof J, Ljubojević M, De Sain-Van Der Velden M, Vuković J, Fumić K, Sadiković B, Barić I. Hypogammaglobulinemia and imaging features in a patient with infantile free sialic acid storage disease (ISSD) and a novel mutation in the SLC17A5 gene. J Pediatr Endocrinol Metab. 2018;31(10):1155-9. DOI: 10.1515/jpem-2017-0397. PMID: 30243016

2017 Publications

    1. Abbott JA, Guth E, Kim C, Regan C, Siu VM, C. Rupar CA, Demeler B, Francklyn CS, Robey-Bond SM. The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity. Biochemistry. 2017 Jul 18;56(28):3619-3631. doi: 10.1021/acs.biochem.7b00114. Epub 2017 Jul 7. PMID: 28632987.
    2. Abulizi P, Loganathan N, Zhao D, Mele T, Zhang Y, Zwiep T, Liu K, Zheng X. Growth Differentiation Factor-15 Deficiency Augments Inflammatory Response and Exacerbates Septic Heart and Renal Injury Induced by Lipopolysaccharide. Sci Rep. 2017 Apr 21;7(1):1037. doi: 10.1038/s41598-017-00902-5. PMID: 28432312.
    3. Adams PC, Howlett CJ. Xenocostas A. Chakrabarti S. Sex-specific analysis post liver transplantation in hemochromatosis with aplastic anemia and late onset hepatocellular carcinoma. Hepatology comm. DOI: 10.1002/hep4.1122, 2017
    4. Alturkustani M, Ang LC, Ramsay D. Pathology of toxic leucoencephalopathy in drug abuse supports hypoxic-ischemic pathophysiology/etiology. Neuropathology. 2017 Mar 9. doi: 10.1111/neup.12377. [Epub ahead of print] PMID: 28276094.
    5. Alvarez-Elías AC, Yoo EC, Todorova EK, Singh RN, Filler G. A Retrospective Study on Mycophenolic Acid Drug Interactions: Effect of Prednisone, Sirolimus, and Tacrolimus With MPA.  The Drug Monit 2017/06/01 .  39 (3) p220-228.  doi: 10.1097/FTD.0000000000000403 / PMID 28437284.
    6. Anderson PT, Gottheil S, Gabril M, Barra L, Power N. Acute urinary retention secondary to urethral involvement of granulomatosis with polyangiitis. Can Urol Assoc J. 2017 Jan-Feb;11(1-2):E38-E40. doi: 10.5489/cuaj.3555. Epub 2017 Jan 12. PMID: 28163812.
    7. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Siu V, Rodenhiser D, Schwartz C, Sadikovic B. Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders. J Mol Diagn, 2017 Aug 11, Senior Responsible Author, DOI: 10.1016/j.jmoldx.2017.07.002. PMID 28807811.
    8. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Rodenhiser D, Schwartz C, Sadikovic B. The defining DNA methylation signature of Kabuki syndrome enables functional assessment of genetic variants of unknown clinical significance. Epigenetics. 2017 Sep 21:0. doi: 10.1080/15592294.2017.1381807. [Epub ahead of print]. PMID 28933623.
    9. Balci TB, Hartley T, Xi Y, Dyment DA, Beaulieu CL, Bernier FP, Dupuis L, Horvath GA, Mendoza-Londono R, Prasad C, Richer J, Yang XR, Armour CM, Bareke E, Fernandez BA, McMillan HJ, Lamont RE, Majewski J, Parboosingh JS, Prasad AN, Rupar CA, Schwartzentruber J, Smith AC, Tétreault M; FORGE Canada Consortium; Care4Rare Canada Consortium, Innes AM, Boycott KM. Debunking Occam’s razor: Diagnosing multiple genetic diseases in families by whole exome sequencing. Clin Genet. 2017 Sep;92(3):281-289. doi: 10.1111/cge.12987. Epub 2017 Mar 13. PMID: 28170084.
    10. Banaschewski BJH, Baer B, Arsenault C, Jazey T, Veldhuizen EJA, Delport J, Gooyers T, Lewis JF, Haagsman HP, Veldhuizen RAW, Yamashita C. The Antibacterial and Anti-inflammatory Activity of Chicken Cathelicidin-2 combined with Exogenous Surfactant for the Treatment of Cystic Fibrosis-Associated Pathogens. Sci Rep. 2017 Nov 14;7(1):15545. doi: 10.1038/s41598-017-15558-4. PMID: 29138462.
    11. Barton M, McKelvie B, Campigotto A, Mullowney T. Legionellosis following water birth in a hot tub in a Canadian neonate. CMAJ. 2017 Oct 23;189(42):E1311-E1313. doi: 10.1503/cmaj.170711. PMID: 29061856
    12. Beamish CA, Mehta S, Strutt BJ, Chakrabarti S, Hara M, Hill DJ. Decrease in Ins+Glut2LO ß-cells with advancing age in mouse and human pancreas. J Endocrinol. 2017 Jun;233(3):229-241. doi: 10.1530/JOE-16-0475. Epub 2017 Mar 27. PMID: 28348115
    13. Bhayana V, Ismail OZ. Asymptomatic Hyperphosphatasemia Three Months Following Pediatric Liver Transplantation. Clin Chem Lab Med 2017; 55, Special Suppl, pp S1506-1630.
    14. Biwas S, Chakrabarti S. Pathogenetic Mechanisms in Diabetic Retinopathy: From Molecules to Cells to Tissues. In: Kartha CC, Ramachandran S, Pillai R, editor(s). Mechanisms of Vascular Defects in Diabetes Mellitus. Springer; 2017. p.209-247. Book Chapter.
    15. Blake A, Dragan M, Tirona RG, Hardy DB, Brackstone M, Tuck AB, Babwah AV, Bhattacharya M. G protein-coupled KISS1 receptor is overexpressed in triple negative breast cancer and promotes drug resistance. Sci Rep. 2017 Apr 19;7:46525. doi: 10.1038/srep46525. PMID: 28422142.
    16. Bone KM, Chernos J, Perrier R, Innes AM, Bernier FP, McLeod R, Thomas MA. Mosaic trisomy 1q: a recurring chromosome anomaly that is a diagnostic challenge and is associated with a Fryns-like phenotype. Prenatal Diagnosis. 2017 Apr 24. DOI: 10.1002/pd.5058. [Epub ahead of print] PMID: 28437579.
    17. Boyd DA, Mataseje LF, Davidson R, Delport JA, Fuller J, Hoang L, Lefebvre B, Levett PN, Roscoe DL, Willey BM, Mulvey MR. Enterobacter cloacae Complex Isolates Harboring blaNMC-A or blaIMI-Type Class A Carbapenemase Genes on Novel Chromosomal Integrative Elements and Plasmids. Antimicrob Agents Chemother. 2017 Apr 24;61(5). pii: e02578-16. doi: 10.1128/AAC.02578-16. Print 2017 May. PMID: 28223374
    18. Brackstone M, Palma D, Tuck AB, Scott L, Potvin K, Vandenberg T, Perera F, D'Souza D, Taves D, Kornecki A5, Muscedere G, Chambers AF. Concurrent Neoadjuvant Chemotherapy and Radiation Therapy in Locally Advanced Breast Cancer. Int J Radiat Oncol Biol Phys. 2017 Nov 15;99(4):769-776. doi: 10.1016/j.ijrobp.2017.06.005. Epub 2017 Jun 20. PMID: 28870785
    19. Brewer-Deluce D, Gibson CJ. Teaching Matters: Developing Teaching Dossiers to Showcase Teaching Success and Competency. Teaching Innovation Projects: Vol. 7: Iss. 1 Article 1, 2017. Available at: http://ir.lib.uwo.ca/tips/vol7/iss1/1
    20. Budhram A, Leung A, Sangle N, Khaw AV. Diffuse Large B-Cell Lymphoma of the Nasopharynx Presenting With Cluster-Like Headache. Headache. 2017 Mar 13. doi: 10.1111/head.13065. [Epub ahead of print]. PMID: 28295284.
    21. Budhram A, Gabril MY, Lee DH, Fraser JA. Hypertrophic Pachymeningitis With Optic Neuropathy Heralding Systemic Vasculitis. Can J Neurol Sci. 2017 Jan;44(1):105-107. doi: 10.1017/cjn.2016.51. Epub 2016 May 17. PMID: 27184909.
    22. Buzea C, Pacheco I. (2017) Nanomaterials and their classification. In: EMR/ESR/EPR spectroscopy for characterization of nanomaterials. Springer Book Series: Advance Structured Materials, ISBN 978-81-322-3653-5 ISBN 978-81-322-3655-9. http://www.springer.com/la/book/9788132236535.
    23. Cecchini MJ, Walsh JC, Parfitt J, Chakrabarti S, Correa R, MacKenzie MJ, Driman DK . The Utility of CDX2 loss as a prognostic marker in state II colon cancer.   2017/07/01.
    24. Chakrabarti S, Sen S, Lui EMK. Effect of ginseng therapy on diabetes and its chronic complications: lessons learned. J Complement Integr Med. 2017 May 11;14(4). pii: /j/jcim.2017.14.issue-4/jcim-2016-0166/jcim-2016-0166.xml. doi: 10.1515/jcim-2016-0166. Published Online: 2017-05-11. PMID: 29345436
    25. Chen BB, Prasad C, Walsh JC, Ashok D. Eight-year-old girl with hepatomegaly. Paediatr Child Health (2017) 22 (3): 115-116.  DOI: https://doi.org/10.1093/pch/pxx036 .
    26. Chen S, Feng B, Thomas AA, Chakrabarti S. miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes. PLoS One. 2017 Mar 16;12(3):e0173918. doi: 10.1371/journal.pone.0173918. eCollection 2017. PMID 28301595.
    27. Chin-Yee B, Lazo-Langner A, Butler-Foster T, Hsia C, Chin-Yee I. Blood donation and testosterone replacement therapy.  Transfusion 2017/03/01: 57 (3) p578-581.  doi: 10.1111/trf.13970 / PMID 28150363.
    28. Darling MR, Woodford R, Cuddy KK, Jackson-Boeters L, Hayter A, Inkaran J, Diamandis EP, Khan Z. Kallikrein-related peptidase expression in odontogenic cysts and tumors: An immunohistochemical comparative study. J Investig Clin Dent. 2017 Jan 4. DOI: 10.1111/jicd.12256. [Epub ahead of print] PMID: 28054463.
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    111. Santyr BG, Goubran M, Lau JC, Kwan BYM, Salehi F, Lee DH, Mirsattari SM, Burneo JG, Steven DA, Parrent AG, de Ribaupierre S, Hammond RR, Peters TM, Khan AR. Investigation of hippocampal substructures in focal temporal lobe epilepsy with and without hippocampal sclerosis at 7T. J Magn Reson Imaging, 2017 May 1; 45 (5): 1359-1370, Coauthor, DOI: 10.1002/jmri.25447.
    112. Schenkel LC, Rodenhiser D, Siu V, McCready E, Ainsworth P, Sadikovic B. Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors. J Pediatr Genet. 2017 Mar;6(1):30-41. [Epub 2016 Nov 8] DOI: 10.1055/s-0036-1593849 PMID: 28180025.
    113. Schenkel LC, Kernohan KD, McBride A, Reina D, Hodge A, Ainsworth PJ, Rodenhiser DI, Pare G, Bérubé NG, Skinner C, Boycott KM, Schwartz C, Sadikovic B. Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome. Epigenetics Chromatin. 2017 Mar 10;10:10. doi: 10.1186/s13072-017-0118-4. eCollection 2017 Mar 10. PMID: 28293299.
    114. Shi T, Wehrli BM. Monophasic Synovial Sarcoma of the Hypopharynx Excised by Transoral Laser Microsurgery.  Journal of Laryngology and Voice 2017/01/01. 
    115. Shirley B, Li Y, Knoll JHM, Rogan PK. Expedited radiation biodosimetry by automated dicentric chromosome identification and dose estimation, J Vis Exp. 2017 Sep 4;(127). doi: 10.3791/56245. PMID: 28892030.
    116. Srigley JA, Pelude L, Thampi N, Vayalumkal J, Amaratunga K, Bush K, Collet JC, Ellis C, Embree J, Forrester L, Frenette C, Henderson E, John MA, Johnston BL, Langley JM, Lee BE, Lefebvre M-A, Lemieux C, McGeer A, Noseworthy E, Quach C, Richardson S, Scien . Central Line-Associated Bloodstream Infections in Canadian Pediatric and Neonatal Intensive Care Units: 2009-2015.  Association of Medical Microbiology and Infectious Diseases Canada 2017/05/04.  
    117. Sullivan R, Mc Girr R, Hu S, Tan A, Wu D, Charron C, Lalonde T, Arany E, Chakrabarti S, Luyt L,  Dhanvantari S. Changes in the cardiac GHSR1a-Ghrelin system correlate with myocardial dysfunction in diabetic cardiomyopathy in mice.  Journal of the Endocrine Society. 2017 Dec 28;2(2):178-189. doi: 10.1210/js.2017-00433. eCollection 2018 Feb 1. PMID: 29450407
    118. Tahmasebi H, Higgins V, Fung AWS, Truong D, White-Al Habeeb NMA, Adeli K. Pediatric Reference Intervals for Biochemical Markers: Gaps and Challenges, Recent National Initiatives and Future Perspectives.  EJIFCC 2017/03/01: 28 (1) p43-63.  / PMID 28439218.
    119. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 Jan 12;541(7636):169-175. doi: 10.1038/nature20805. Epub 2017 Jan 4. PMID:28052061.
    120. The Cancer Genome Atlas Research Network (Lists of participants and their affiliations appear in the online version of the paper; incl Parfitt J, collaborator). Integrated genomic and molecular characterization of cervical cancer. Nature. 2017 Mar 16;543(7645):378-384. doi: 10.1038/nature21386. Epub 2017 Jan 23. PMID: 28112728.
    121. Thomas AA, Feng B, Chakrabarti S. ANRIL: A Regulator of VEGF in Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):470-480. doi:10.1167/iovs.16-20569. PMID: 28122089.
    122. Thwaites M J, Cecchini MJ, Talluri S, Passos DT, Carnevale J, Dick FA. Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control. Cell Div. 2017; 12: 3. PMCID: PMC5348811 DOI: 10.1186/s13008-017-0029-6.
    123. Tijssen JA, Filler G. When CRRT on ECMO Is Not Enough for Potassium Clearance: A Case Report.  Can J Kidney Health Dis 2017/01/01: 4 p2054358117722559.  doi: 10.1177/2054358117722559 / PMID 28856008.
    124. Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ. Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders. Brain. 2017 Sep 1;140(9):2460-2474. doi: 10.1093/brain/awx172. PMID: 29050386
    125. Tota JE, Bentley J, Blake J, Coutlée F, Duggan MA, Ferenczy A, Franco EL, Fung-Kee-Fung M, Gotlieb W, Mayrand MH, McLachlin M, Murphy J, Ogilvie G, Ratnam S. Introduction of molecular HPV testing as the primary technology in cervical cancer screening: Acting on evidence to change the current paradigm. Prev Med. 2017 May;98:5-14. doi: 10.1016/j.ypmed.2016.11.029. Epub 2017 Feb 6. PMID: 28279264.
    126. Tota JE, Bentley J, Blake J, Coutlée F, Duggan MA, Ferenczy A, Franco EL, Fung-Kee-Fung M, Gotlieb W, Mayrand MH, McLachlin M, Murphy J, Ogilvie G, Ratnam S. Approaches for triaging women who test positive for human papillomavirus in cervical cancer screening. Prev Med. 2017 May;98:15-20. doi: 10.1016/j.ypmed.2016.11.030. Epub 2017 Feb 6. PMID: 28279257.
    127. Wang L, Huang Z, Huang W, Chen X, Shan P, Zhong P, Khan Z, Wang J, Fang Q, Liang G, Wang Y. Inhibition of epidermal growth factor receptor attenuates atherosclerosis via decreasing inflammation and oxidative stress. Sci Rep. 2017 Apr 4;8:45917. doi: 10.1038/srep45917. PMID: 28374780.
    128. White-Al Habeeb NM. Downregulation of PDZ Domain Containing 1 (PDZK1) is a Poor Prognostic Marker for Clear Cell Renal Cell Carcinoma.  EBioMedicine 2017/02/01: 16 p20-21.  doi: 10.1016/j.ebiom.2017.01.012 / PMID 28109828.
    129. White-Al Habeeb NMA, Earle T, Spencer M, Blasutig IM. Evaluation of the N-latex serum free light chain assay on the Siemens BNII analyzer and agreement with The Binding Site FreeLite assay on the SPAPlus.  Clin Biochem 2017/05/13:  doi: 10.1016/j.clinbiochem.2017.05.009 / PMID 28512013.
    130. Yan B, Feagan B, Teriaky A, Mosli M, Mohamed R, Williams G, Yeung E, Yong E, Haig A, Sey M, Stitt L, Zou GY, Jairath V. Reliability of EUS indices to detect inflammation in ulcerative colitis.Gastrointest Endosc. 2017 Jul 29. pii: S0016-5107(17)32158-2. doi: 10.1016/j.gie.2017.07.035. [Epub ahead of print]. PMID 28760533
    131. Yildirim ZK, Nexo E, Rupar T, Büyükavci M. Seven Patients With Transcobalamin Deficiency Diagnosed Between 2010 and 2014: A Single-Center Experience. J Pediatr Hematol Oncol. 2017 Jan;39(1):38-41. PMID: 27824740.
    132. Yu J, Elsayed S, Sun D. A 44-year-old man with acute asymmetric polyarthritis and fever. CMAJ. 2017 Jun 26;189(25):E861-E864. doi: 10.1503/cmaj.170093. DOI: 10.1503/cmaj.170093 PMID: 28652481
    133. Zhang Y, Moszczynski LA, Liu Q, Jiang J, Zhao D, Quan D, Mele T, McAlister V, Jevnikar A, Baek SJ, Liu K, Zheng X. Growth Differentiation Factor 15 (GDF15) Preventing Cold Ischemia Reperfusion Injury (I/R) in Heart Transplantation through Foxo3a Signaling. Oncotarget. 2017 May 30; 8(22):36531- 36544. doi: 10.18632/oncotarget.16607. PMID: 28388574
    134. Zhang Q, Shibani A, Sadikovic B, Howlett CJ, Ang LC. an aggressive multifocal primary CNS histiocytosis with PTPN11 (Shp2) mutation.Neuropathol Appl Neurobiol. 2017 Apr 12. doi: 10.1111/nan.12404. [Epub ahead of print]. PMID: 28403515.
    135. Zhang Y, Zhang G, Liu Y, Chen R, Zhao D, McAlister V, Mele T, Liu K, Zheng X. GDF15 Regulates Malat-1 Circular RNA and Inactivates NFκB Signaling Leading to Immune Tolerogenic DCs for Preventing Alloimmune Rejection in Heart Transplantation. Front Immunol. 2018 Oct 30; 9:2407. doi: 10.3389/fimmu.2018.02407. eCollection 2018. PMID: 30425709
    136. Zou C, Li W, Li J, Khan ZA, Pan Y, Wu X, Yin H, Wang J, Zheng C, Liang G. 11β-HSD1 inhibition ameliorates diabetes-induced cardiomyocyte hypertrophy and cardiac fibrosis through modulation of EGFR activity. Oncotarget. 2017 Oct 24;8(56):96263-96275. doi: 10.18632/oncotarget.22015. eCollection 2017 Nov 10. PMID: 29221204.

2016 Publications

    1. Schenkel LC, Schwartz C, Skinner C, Rodenhiser DI, Ainsworth PJ, Pare G, Sadikovic B.  Clinical Validation of Fragile X Syndrome Screening by DNA Methylation Array.  J Mol Diagn. 2016 Nov;18(6):834-841.  doi: 10.1016/j.jmoldx.2016.06.005.  PMID: 27585064
    2. Schenkel LC, Rodenhiser DI, Ainsworth PJ, Paré G, Sadikovic B.  DNA methylation analysis in constitutional disorders: Clinical implications of the epigenome.  Crit Rev Clin Lab Sci. 2016;53(3):147-65.  DOIi: 10.3109/10408363.2015.1113496. Review.  PMID: 26758403
    3. Kernohan KD, Cigana Schenkel L, Huang L, Smith A, Pare G, Ainsworth P; Care4Rare Canada Consortium., Boycott KM, Warman-Chardon J, Sadikovic B.  Identification of a methylation profile for DNMT1-associated autosomal dominant cerebellar ataxia, deafness, and narcolepsy.  Clin Epigenetics. 2016 Sep 5;8:91. doi: 10.1186/s13148-016-0254-x.  PMID: 27602171 Free PMC Article
    4. Hood RL, Schenkel LC, Nikkel SM, Ainsworth PJ, Pare G, Boycott KM, Bulman DE, Sadikovic B. The defining DNA methylation signature of Floating-Harbor Syndrome. Sci Rep, 2016 Dec 9; 6: 38803.  DOI: 10.1038/srep38803. PMID 27934915.
    5. Iqbal J, Nussenzweig A, Lubinski J, Byrski T, Eisen A, Bordeleau L, Tung NM, Manoukian S, Phelan CM, Sun P, Narod SA, Hereditary Breast Cancer Research Group (incl. Ainsworth P). The incidence of leukaemia in women with BRCA1 and BRCA2 mutations: an International Prospective Cohort Study. Br J Cancer, 2016 May 10; 114 (10): 1160-4.  DOI: 10.1038/bjc.2016.58. PMID 26986251.
    6. Gronwald J, Glass K, Rosen B, Karlan B, Tung N, Neuhausen SL, Moller P, Ainsworth P, Sun P, Narod SA, Lubinski J, Kotsopoulos J, Hereditary Breast Cancer Clinical Study Group. Treatment of infertility does not increase the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation. Fertil Steril. 2016 Mar 1, 105. (3): p.781-5.  DOI: 10.1016/j.fertnstert.2015.11.034. PMID 26698676
    7. Florendo-Cumbermack A, Selchen D, Morrow SA, Sharma M, Steven D, Ang LC, Casserly C, Burneo J, Kremenchutzky M, Hammond R.   Everything Old is New Again.  Can J Neuro Sci.  Volume 43, Issue 1, 5 Jan 2016, Pages 213-218  DOI:  10.1017/cjn.2015.309
    8. Mattingly TK, Denning LM, Siroen KL, Lehrbass B, Lopez-Ojeda P, Stitt L, Pelz DM, Das S, Ang LC, Lee DH, Lownie SP. Catheter based selective hypothermia reduces stroke volume during focal cerebral ischemia in swine. J Neurointerv Surg. 2016 Apr;8(4):418-22. doi: 10.1136/neurintsurg-2014-011562. Epub 2015 Feb 12. PMID: 25676148
    9. Tong J, Fitzmaurice PS, Moszczynska A, Mattina K, Ang LC, Boileau I, Furukawa Y, Sailasuta N, Kish SJ. Do glutathione levels decline in aging human brain? Free Radic Biol Med, 2016 Apr; 93: 110-7. Doi: 10.1016/j.freeradbiomed.2016.01.029.
    10. Alturkustani M, Ang LC. Acute hypoxic-ischemia in cardiac arrest encephalopathy causes only minimal demyelination. Neuropathology 2016 Mar; doi:10.1111/neup.12287.
    11. Beamish CA, Strutt BJ, Arany EJ, Hill DJ. Insulin-positive, Glut2-low cells present within mouse pancreas exhibit lineage plasticity and are enriched within extra-islet endocrine cell clusters. Islets. 2016 Mar 24:e1162367. [Epub ahead of print] PMID: 27010375
    12. Whitehead R, Guan H, Arany E, Cernea M, Yang K.  Prenatal exposure to bisphenol A alters mouse fetal pancreatic morphology and islet composition.  Horm Mol Biol Clin Investig.  2016 Mar;25(3):171-9. DOI: 10.1515/hmbci-2015-0052  PMID: 26812801.

    13. Quansah R, Bend JR, Abdul-Rahaman A, Armah FA, Luginaah I, Essumang DK, Iddi S, Chevrier J, Cobbina SJ, Nketiah-Amponsah E, Adu-Kumi S, Darko G, Afful S. Associations between pesticide use and respiratory symptoms: A cross-sectional study in Southern Ghana. Environ Res. 2016 Jun 16;150:245-254. doi: 10.1016/j.envres.2016.06.013. PMID: 27318967
    14. Palikhe NS, Laratta C, Nahirney D, Vethanayagam D, Bhutani M, Vliagoftis H, Cameron L. Elevated levels of circulating CD4(+) CRTh2(+) T cells characterize severe asthma. Clin Exp Allergy, 2016 Jun;46(6):825-36. DOI: 10.1111/cea.12741  PMID:  27079298.
    15. Ethier C, Yu Y, Cameron L, Lacy P, Davoine F.  Calcitriol Reduces Eosinophil Necrosis Which Leads to the Diminished Release of Cytotoxic Granules.  Int Arch Allergy Immunol. 2016;171(2):119-129. DOI: 10.1159/000450951. Epub 2016 Dec 1.  PMID:  27902981

    16. Campigotto A, Muller MP, Taggart LR, Haj R, Leung E, Nadarajah J, Matukas LM. Cumulative Antimicrobial Susceptibility Data from Intensive Care Units at One Institution: Should Data Be Combined? J Clin Microbiol, 2016 Apr 1; 54 (4): 956-9.  DOI: 10.1128/JCM.02992-15.

    17. Campigotto A, Richardson SE, Sebert M, McElvania TeKippe E, Chakravarty A, Doern CD. 2016. Low utility of pediatric isolator blood culture system for detection of fungemia in children: a 10-year review. J Clin Microbiol 54:2284–2287. DOI: 10.1128/JCM.00578-16.
    18. Thwaites MJ, Cecchini MJ, Passos DT, Welch I, Dick FA.  Interchangeable roles for E2F transcriptional repression by the retinoblastoma protein and p27KIP1-CDK regulation in cell cycle control and tumor suppression.  Mol Cell Biol. 2016 Nov 7. pii: MCB.00561-16. [Epub ahead of print]  DOI: 

      10.1128/MCB.00561-16  PMID:.27821477
    19. Ishak CA, Marshall AE, Passos DT, White CR, Seung KJ , Cecchini MJ, Ferwati S, MacDonald WA, Howlett CJ, Welch ID, Rubin SM, Mann MRW, Dick FA.  An RB-EZH2 Complex Mediates Silencing of Repetitive DNA Sequences.  Mol Cell Biol. 2016 Nov 23. [Epub ahead of print]  DOI:  10.1016/j.molcel.2016.10.021

    20. Chakrabarti S. MicroRNA15a- A Molecule Modulating Multiple Pathologies in Diabetic Retinopathy. (Invited commentary). EBioMedicine. 2016 Sep;11:13-14. doi: 10.1016/j.ebiom.2016.08.017. Epub 2016 Aug 13. PMID: 27546691

    21. Gordon A, Feng B, Chakrabarti S Long Non-coding RNA malat-1 regulates inflammatory cytokines in chronic diabetic complications. Diabetes 2016 Jun; 65 (Supplement 1), A137/525-P
    22. Feng B, Chen S, Gordon A, Chakrabarti S. Antiinflammatory and antifibrotic effects of endothelial miRNA146 in the heart in diabetes. Diabetes 2016 Jun; 65 (Supplement 1); A125/474-P.
    23. Li B, Iordanous Y, Chakrabarti S, Alan LH, Adenoid Cystic Carcinoma Presenting as a Retro-orbital mass, Can J Ophthalmol. 2016 Apr;51(2):e65-7. doi: 10.1016/j.jcjo.2015.12.012.
    24. Feng B, Cao Y, Chen S, Chu X, Chu Y, Chakrabarti S. miR-200b mediates endothelial to mesenchymal transition in diabetic cardiomyopathy. Diabetes. 2016 Mar;65(3):768-79. doi: 10.2337/db15-1033. Epub 2015 Dec 30. PMID: 26718496
    25. Zhang Q, Hussey A, Ubaidat M, Chan N, Gomez JA. Malignant Mesothelioma of the Tunica Vaginalis Testis: A Case Report and Review of Literature. Canadian Journal of Pathology 2016/03/01 19-23 .
    26. Ostrakhovitch EA, Song YP,  Cherian MG. Basal and copper-induced expression of metallothionein isoform 1,2 and 3 genes in epithelial cancer cells: The role of tumor suppressor P53. Journal of Trace Elements in Medicine and Biology Volume 35, May 2016, Pages 18–29 DOI: 10.1016/j.jtemb.2016.01.008.
    27. Chin-Yee B, Lazo-Langner A, Butler-Foster T, Hsia C, Chin-Yee I. Blood donation and testosterone replacement therapy. Transfusion. 2017 Mar;57(3):578-581. doi: 10.1111/trf.13970. Epub 2017 Feb 1. PMID: 28150363.
      Parviz Y, Hsia C, Alemayehu M, Wall S, Bagur R, AbuRomeh N, Chin-Yee I, Lavi S. The effect of fresh versus standard blood transfusion on microvascular endothelial function. Am Heart J. 2016 Nov;181:156-161. doi: 10.1016/j.ahj.2016.05.021. Epub 2016 Aug 26. PMID: 27823688.
    28. Hsia CC, Mahon JL, Seitelbach M, Chia J, Zou G, Chin-Yee IH. Use of n-of-1 (single patient) trials to assess the effect of age of transfused blood on health-related quality of life in transfusion-dependent patients. Transfusion, 2016 May 1; 56 (5): 1192-200.  DOI: 10.1111/trf.13484. PMID 26840915

    29. Louzada ML, Hsia CC, Al-Ani F, Ralley F, Xenocostas A, Martin J, Connelly SE, Chin-Yee IH, Minuk L, Lazo-Langner A. Randomized double-blind safety comparison of intravenous iron dextran versus iron sucrose in an adult non-hemodialysis outpatient population: A feasibility study. BMC Hematol, 2016 Jan 1; 16: 7.  DOI: 10.1186/s12878-016-0046-8. PMID 26973791
    30. da Silveira Cavalcante L, Feng Q, Chin-Yee I, Acker JP, Holovati JL. Effect of liposome-treated red blood cells in an anemic rat model. J Liposome Res, 2016 Apr 8: 1-8.  DOI: 10.3109/08982104.2016.1149867. PMID 27055898
    31. Gupta M, Copley K, Keeney M, Chin-Yee I.  Does Cell Size Matter?: Utilizing Mean Cell Volume in Hospitalized Patients As a Screen to Determine Common Causes of Anemia Including Iron Deficiency Anemia, Vitamin B12 and Folate Deficiency. Blood. 2016 Dec:128(22):2338
    32. Gottheil S, Khemani E, Copley K, Keeney M, Kinney J, Chin-Yee I, Gob A. Reducing inappropriate ESR testing with computerized clinical decision support. BMJ Qual Improv Rep, 2016 Jan 1; 5 (1).  DOI: 10.1136/bmjquality.u211376.w4582. PMID 27096092
    33. Delport JA, Mohorovic I, Lannigan R, Burn S, McCormick JK, Conkey B, MacDonald K, Schaus DG, John MA. Rapid Detection of Methicillin Resistant Staphylococcus aureus (MRSA) Bacteremia Using A Combined Three Hour Short-Incubation MALDI-TOF Identification and the Alere Culture Colony Test PBP2a Detection Test. J Med Microbiol. 2016 May 23. DOI: 10.1099/jmm.0.000285. [Epub ahead of print].  PMID:  27221546
    34. Delport JA, Strikwerda A, Armstrong A, Schaus D, John M. Quality of Care Is Improved by Rapid Short Incubation MALDI-ToF Identification from Blood Cultures as Measured by Reduced Length of Stay and Patient Outcomes as Part of a Multi-Disciplinary Approach to Bacteremia in Pediatric Patients. PLoS One, e0160618. DOI: 10.1371/journal.pone.0160618. PMID 27513860.
    35. Chadwick SR, Pananos AD, Di Gregorio SE, Park AE, Etedali-Zadeh P, Duennwald ML, Lajoie P. A Toolbox for Rapid Quantitative Assessment of Chronological Lifespan and Survival in Saccharomyces cerevisiae. Traffic, 2016 Jun 1; 17 (6): 689-703  DOI: 10.1111/tra.12391  PMID 26939796.
    36. Hoffmann KS, Duennwald ML, Karagiannis J, Genereaux J, McCarton AS, Brandl CJ. Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response. G3 (Bethesda), 2016 Apr 6  DOI: 10.1534/g3.116.029520  PMID 27172216.
    37. Jiang Y, Di Gregorio SE, Duennwald ML, Lajoie P. Polyglutamine toxicity in yeast uncovers phenotypic variations between different fluorescent protein fusions. Traffic. 2016 Oct 13. doi: 10.1111/tra.12453. PMID:27734565.
    38. Zurawel AA, Kabeche R, DiGregorio SE, Deng L, Menon KM, Opalko H, Duennwald ML, Moseley JB, Supattapone S. CAG Expansions Are Genetically Stable and Form Nontoxic Aggregates in Cells Lacking Endogenous Polyglutamine Proteins. MBio. 2016 Sep 27;7(5). pii: e01367-16. doi: 10.1128/mBio.01367-16. PMID: 27677791

    39. Leach MD, Kim T, DiGregorio S, Collins C, Zhang Z, Duennwald ML, Cowen LE. Candida albicans Is Resistant to Polyglutamine Aggregation and Toxicity. G3 (Bethesda). 2016 Nov 2. pii: g3.116.035675. doi: 10.1534/g3.116.035675. [Epub ahead of print] PMID:27807047

    40. Carroll CS, Amankwa LN, Pinto LJ, Fuller JD, Moore MM. Detection of a Serum Siderophore by LC-MS/MS as a Potential Biomarker of Invasive Aspergillosis. PLoS One 2016 Mar 14;11(3):e0151260 DOI:  10.1371/journal.pone.0151260  PMID:  26974544
    41. Charles MK, Berenger BM, Turnbull L, Rennie R, Fuller J. Variability of β-lactam susceptibility testing for Streptococcus pneumoniae using 4 commercial test methods and broth microdilution. Diagn Microbiol Infect Dis 2016 Mar;84(3):240-5 DOI:  10.1016/j.diagmicrobio.2015.11.014 PMID:  26707068
    42. Budhram A, Gabril MY, Lee DH, Fraser JA. Hypertrophic Pachymeningitis With Optic Neuropathy Heralding Systemic Vasculitis. Can J Neurol Sci, 2016 May 17: 1-3  DOI: 10.1017/cjn.2016.51  PMID 27184909.
    43. Nofech-Mozes R, Khella HW, Scorilas A, Youssef L, Krylov SN, Lianidou E, Sidiropoulos KG, Gabril M, Evans A, Yousef GM. MicroRNA-194 is a Marker for Good Prognosis in Clear Cell Renal Cell Carcinoma. Cancer Med, 2016 Apr 1; 5 (4): 656-64 DOI: 10.1002/cam4.631  PMID 26860079.
    44. Ibrahim G, Gabril M, Howlett CJ.  PTEN expression in chromophobe renal cell carcinoma versus clear cell renal cell carcinoma. Modern Pathology, 239A-240A, 2016/03.  
    45. Gibson CJ, Abrams KJ, Pletcher T. (2016)   Health Information Exchange as a Profession. In: HEALTH INFORMATION EXCHANGE: Navigating and Managing a Network of Health Information Systems.  Academic Press / Elsevier.  p.21-38.  DOI: 10.1016/B978-0-12-803135-3.00002-5

    46. Martin PE, Gaed M, Gomez JA, Moussa M, Gibson E, Cool DW, Chin JL, Pautler S, Fenster A, Ward AD. How does prostate biopsy guidance error impact pathologic cancer risk assessment? Proc. SPIE9786, Medical Imaging 2016: Image Guided Procedure, Robotic Interventions, and Modeling.   9786.  DOI:  10.1117/12.2217334
    47. Lin S, Visram F, Liu W, Haig A, Jiang J, Mok A, Lian D, Wood ME, Torregrossa R, Whiteman M, Lobb I, Sener A. GYY4137, a slow-releasing hydrogen sulfide donor, ameliorates renal damage associated with chronic obstructive uropathy. J Urol. 2016 May 10. pii: S0022-5347(16)30385-8. doi: 10.1016/j.juro.2016.05.029. [Epub ahead of print].
    48. Lobb I, Jiang J, Lian D, Liu W, Haig A, Saha MN, Torregrossa R, Wood ME, Whiteman M, Sener A. Hydrogen Sulfide Protects Renal Grafts Against Prolonged Cold Ischemia-Reperfusion Injury via Specific Mitochondrial Actions. Am J Transplant. 2016 Oct 15. DOI: 10.1111/ajt.14080. [Epub ahead of print] PMID: 27743487.

      Spence JD, Hammond R. (2016)  Hypertension and Stroke. In: Hypertension and the Brain as an End-Organ Target. Springer International Publishing  p.39-54 DOI: 10.1007/978-3-319-25616-0_3.
    49. Magaki S, Chang E, Hammond RR, Yang I, Mackenzie IR, Chou BT, Choi SI, Jen JC, Pope WB, Bell DA, Vinters HV.  Two cases of rheumatoid meningitis.  Neuropathology 2016 Feb;36(1):93-102.  DOI: 10.1111/neup.12238  PMID:  26350538
    50. Xu A, Matushewski B, Nygard K, Hammond R, Frasch MG, Richardson BS.  Brain Injury and Inflammatory Response to Umbilical Cord Occlusions Is Limited with Worsening Acidosis in the Near-Term Ovine Fetus.  Reprod Sci 2016 Jul 23;23(7):858-70. Epub 2015 Dec 23.  DOI:  10.1177/1933719115623640
    51. Frasch MG, Szynkaruk M6, Prout AP, Nygard K, Cao M, Veldhuizen R, Hammond R, Richardson BS.  Decreased neuroinflammation correlates to higher vagus nerve activity fluctuations in near-term ovine fetuses: a case for the afferent cholinergic anti-inflammatory pathway?  J Neuroinflammation. 2016 May 10;13(1):103. DOI: 10.1186/s12974-016-0567-x  PMID:  27165310

    52. Kurdi M, McGregor S, Hammond R, Siddiqui F, Wehrli B.  Primary Clear Cell Chondrosarcoma of Thoracic Spine: A Rare Tumor in an Uncommon Location. Int J Surg Pathol. 2016 Aug 30 [Epub ahead of print]  DOI: 10.1177/1066896916666317  PMID 27577196.
    53. Kwan BYM, Salehi F, Ohorodnyk P, Lee DH, Burneo JG, Mirsattari SM, Steven D, Hammond R, Peters TM, Khan AR. Usage of SWI (susceptibility weighted imaging) acquired at 7 T for qualitative evaluation of temporal lobe epilepsy patients with histopathological and clinical correlation: An initial pilot study J Clin Neuro Sci  2016 Oct 1; Vol 369, 82-87 DOI: 10.1016/j.jns.2016.07.066
    54. Cocker MS, Spence JD, Hammond R, Wells G, deKemp RA, Lum C, Adeeko A, Yaffe MJ, Leung E, Hill A, Nagpal S, Stotts G, Alturkustani M, Hammond L, DaSilva J, Hadizad T, Tardif JC, Beanlands RS, Canadian Atherosclerosis Imaging Network (CAIN). [18F]-NaF PET/CT Identifies Active Calcification in Carotid Plaque. JACC Cardiovasc Imaging. 2016 Jun 10, Letter to the Editor. DOI: 10.1016/j.jcmg.2016.03.005 PMID 27318719.

    55. Shrum B, Costello P, McDonald W, Howlett C, Donnelly M, McAlister V In-vitro three dimensional culture of hepatocellular carcinoma to measure prognosis and responsiveness to chemotherapeutic agents Hepatobiliary Surgery and Nutrition Vol 5, No 3 (June 2016) 204-8 doi: 10.3978/j.issn.2304-3881.2016.01.01
    56. Puntorieri V, McCaig LA, Howlett CJ, Yao LJ, Lewis JF, Yamashita CM, Veldhuizen RA. Lack of matrix metalloproteinase 3 in mouse models of lung injury ameliorates the pulmonary inflammatory response in female but not in male mice. Exp Lung Res. 2016 Sep 27:1-15. [Epub ahead of print]. PMID 27676418. DOI: 10.1080/01902148.2016.1231243
    57. Theurer JA, Stecho W, Yoo J, Kwan K, Wehrli B, Harry V, Black M, Pinto N, Winquist E, Palma D, Richter S, Barrett JW, Danielle MacNeil S, Fung K, Howlett CJ, Nichols AC. Feasibility of Targeting PIK3CA Mutations in Head and Neck Squamous Cell Carcinoma. Pathol Oncol Res, 2016 Jan 1; 22 (1): 35-40 DOI: 10.1007/s12253-015-9970-3  PMID 26271341.
    58. Schenkel LC, Kerkhof J, Stuart A, Reilly J, Eng B, Woodside C, Levstik A, Howlett CJ, Rupar AC, Knoll JH, Ainsworth P, Waye JS, Sadikovic B.  Clinical Next-Generation Sequencing Pipeline Outperforms a Combined Approach Using Sanger Sequencing and Multiplex Ligation-Dependent Probe Amplification in Targeted Gene Panel Analysis.  J Mol Diagn. 2016 Sep;18(5):657-67. DOI:10.1016/j.jmoldx.2016.04.002.  PMID: 27376475

    59. Zhang Q, Pocrnich C, Kurian A, Hahn AF, Howlett C, Shepherd J, Rizkalla K. Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: A clinicopathologic study of 5 cases. Pathol Res Pract 2015 Sep 5. [epub ahead of print]  DOI:  10.1016/j.prp.2015.08.007 PMID:  26847730
    60. Taylor G, Gravel D, Matlow A, Embree J, LeSaux N, Johnston L, Suh KN, John M, Embil J, Henderson E, Roth V, Wong A. Canadian Nosocomial Infection Surveillance Program. Assessing the magnitude and trends in hospital acquired infections in Canadian hospitals through sequential point prevalence surveys. Antimicrob Resist Infect Control. 2016 May 21;5:19. DOI: 10.1186/s13756-016-0118-3. PMID: 27213039.
    61. Lemieux C, Gardam M, Evans G, John M, Suh KN, vanWalraven C, Vicencio E, Coulby C, Roth V, Hota S.  Longitudinal Multicenter Analysis of Outcomes After Cessation of Control Measures for Vancomycin-Resistant Enterococci.  Infect Control Hosp Epidemiol. 2016 Nov 2:1-7. [Epub ahead of print]   DOI: 10.1017/ice.2016.235  PMID:  27804901.

    62. Roth VR, Mitchell R, Vachon J, Alexandre S, Amaratunga K, Smith S, Vearncombe M, Davis I, Mertz D, Henderson E, John M, Johnston L, Lemieux C, Pelude L, Gravel D, and the Canadian Nosocomial Infection Surveillance Program.  Periprosthetic Infection following Primary Hip and Knee Arthroplasty: The Impact of Limiting the Postoperative Surveillance Period.  Infect Control Hosp Epidemiol. 2016 Nov 11:1-7. [Epub ahead of print]   DOI: 10.1017/ice.2016.256  PMID:  27834161.
    63. Taylor G, Gravel D, Matlow A, Embree J, LeSaux N, Johnston L, Suh KN, John M, Embil J, Henderson E, Roth V, Wong A; Canadian Nosocomial Infection Surveillance Program.  Assessing the magnitude and trends in hospital acquired infections in Canadian hospitals through sequential point prevalence surveys.  Antimicrob Resist Infect Control. 2016 May 21;5:19.  DOI: 10.1186/s13756-016-0118-3. eCollection 2016.  PMID:  27213039

    64. Johnstone J, Chen C, Policarpio M, Adomako K, Rosella L, Lam F, Prematunge C, Nadolny E, Robertson J, Garber G, the Ontario VRE Investigators (includes John, M).  Vancomycin Resistant Enterococcus (VRE) positive blood cultures: results from a province-wide multi-site case series analysis in Ontario, Canada, January 2009 – December 2013.  Open Forum Infect Dis (Fall 2016) 3 (suppl 1)   DOI: 10.1093/ofid/ofw172.155.
    65. Mirham L, Naugler C, Hayes M, Ismil N, Belisle A, Sade S, Streutker C, MacMillan C, Rasty G, Popovic S, Joseph M, Gabril M, Barnes P, Hegele R, Carter B, Yousef G. Performance of residents using digital images versus glass slides on certification examination in anatomical pathology: a mixed methods pilot study CMAJ OPEN 2016/02/25 E88-E94 10.9778/cmajo.20140075.
    66. Paul C, Lin-Shaw A, Joseph M, Kwan K, Sergiacomi G, Mura M.  Successful Treatment of Fibrosing Organising Pneumonia Causing Respiratory Failure with Mycophenolic Acid. Respiration. 2016;92(4):279-282. Epub 2016 Sep 9. DOI: 10.1159/000448846  PMID 27607231

    67. Kim Y, Williams K, Carson T, Jardine E, Chambers AF, Leong HS. Quantification of cancer cell extravasation in vivo. Nat Protoc. 2016 May; 11(5): 937-948. DOI: 10.1038/nprot.2016.050 PMID:27101515

    68. Dorman SN, Baranova K, Knoll JH, Urquhart BL, Mariani G, Carcangiu ML, Rogan PK.  Genomic signatures for paclitaxel and gemcitabine resistance in breast cancer derived by machine learning.  Mol Oncol. 2016 Jan;10(1):85-100 [Epub 2015 Aug 22]  DOI:  10.1016/j.molonc.2015.07.006  PMID:  26372358
    69. Rogan PK, Li Y, Wilkins R, Flegal FN, Knoll JH. Radiation Dose Estimation by Automated Cytogenetic Biodosimetry. 

      Radiat Prot Dosimetry. 2016 Jul 13. [Epub ahead of print] PMID: 27412514

    70. Subasinghe A, Samarabandu J, Li Y, Wilkins R, Flegal F, Knoll JH, Rogan PK. Centromere detection of human metaphase chromosome images using a candidate based method [version 1; referees: 2 approved with reservations].  F1000Research 2016, 5:1565 (doi: 10.12688/f1000research.9075.1)
    71. Mucaki EJ, Caminsky NG, Perri AM, Lu R, Laederach A, Halvorsen M, Knoll JH, Rogan PK. A unified analytic framework for prioritization of non-coding variants of uncertain significance in heritable breast and ovarian cancer. 

      BMC Med Genomics. 2016 Apr 11;9:19. doi: 10.1186/s12920-016-0178-5.PMID: 27067391

    72. Li Y, Knoll JH, Wilkins RC, Flegal FN, Rogan PK. 

      Automated discrimination of dicentric and monocentric chromosomes by machine learning-based image processing. 

      Microsc Res Tech. 2016 May;79(5):393-402. doi: 10.1002/jemt.22642. Epub 2016 Mar 1. PMID: 26929213
    73. Caminsky NG, Mucaki EJ, Perri AM, Lu R, Knoll JH, Rogan PK. Prioritizing Variants in Complete Hereditary Breast and Ovarian Cancer Genes in Patients Lacking Known BRCA Mutations. 

      Hum Mutat. 2016 Jul;37(7):640-52. doi: 10.1002/humu.22972. Epub 2016 Mar 18. PMID: 26898890

    74. Krstic M , Macmillan CD, Leong HS, Clifford AG, Souter LH, Dales DW, Postenka CO, Chambers AF, Tuck AB. The transcriptional regulator TBX3 promotes progression from non-invasive to invasive breast cancer. BMC Cancer 2016 Aug 23;16(1):671 DOI: 10.1186/s12885-016-2697-z PMID: 27553211.
    75. Kubica MGS, Sangle N. Iatrogenic immunodeficiency-associated lymphoproliferative disorders in transplant and nontransplant settings. Indian J Pathol Microbiol. 2016 Jan-Mar;59 ( 1 ) pp. 6 – 15 DOI: 10.4103/0377-4929.178215 PMID: 26960627
    76. Lin HX, Sjaarda J, Dyck J, Stringer R, Hillis C, Harvey M, Carter R, Ainsworth P, Leber B, Pare G, Sadikovic B.  Gender and BCR-ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia.  Eur J Haematol. 2016 Apr;96(4):360-6. DOI: 10.1111/ejh.12597.  PMID: 26059983

    77. Teriaky A, AlNasser A, McLean C, Gregor J, Yan B. The utility of endoscopic biopsies in patients with normal upper endoscopy. Canadian Journal of Gastroenterology and Hepatology 2016, article ID 3026563, pages 1-7. DOI: 10.1016/j.gie.2014.05.051
    78. Gibson E, Bauman GS, Romagnoli C, Cool DW, Bastian-Jordan M, Kassam Z, Gaed M, Moussa M, Gómez JA, Pautler SE, Chin JL, Crukley C, Haider MA, Fenster A, Ward AD. Toward prostate cancer contouring guidelines on MRI: dominant lesion gross and clinical target volume coverage via accurate histology fusion. Int J Radiat Oncol Biol Phys.  2016 04 21 [epub].  DOI:10.1016/j.ijrobp.2016.04.018 (in press)
    79. Ghavidel S, Iman F, Khallaghi S, Gibson E, Khojaste A, Gaed M, Moussa M, Gomez JA, D. Siemens DR, Leveridge M, Chang S, Fenster A, Ward AD, Abolmaesumi P, Mousavi P Classification of Prostate Cancer Grade Using Temporal Ultrasound: in vivo Feasibility Study. Proc. SPIE9786, Medical Imaging 2016: Image Guided Procedure, Robotic Interventions, and Modeling.  9786.  DOI:  10.1117/12.2216922
    80. Williams A, Osmond A, Al Sufiani F, Haig AR, Chan NG, Bütter A. Renal ganglioneuromas in a pediatric patient: Case report and review of the literature. J Pediatr Surg Case Rep, Volume 14, 1 2016 Nov;14:,42-44. DOI: 10.1016/j.epsc.2016.09.007

    81.  

      Pacheco I, Buzea C.   (2016)  Nanoparticle interaction with plants.  Invited book chapter in Nanoscience and Plant-Soil Systems.  Springer Soil Biology Series, 978-3-319-46835-8, Hardcover ISBN 978-3-319-46833-4.   http://www.springer.com/us/book/9783319468334.
    82. Buzea C, Pacheco I.  (2016)  Nanomaterials and nanoparticles: origin and activity. In:  Nanoscience and Plant-Soil Systems.  Springer Soil Biology Series, 978-3-319-46835-8, Hardcover ISBN 978-3-319-46833-4.   http://www.springer.com/us/book/9783319468334.​
    83. Arifin A, Driman DK, Parfitt J. Liver Nodules Crash Course. MedEdPORTAL, 2016 Apr 14; Available from: https://www.mededportal.org/publication/10396
    84. Cancer Genome Atlas Research Network (affiliated with Ontario Tumour Bank: Albert M, Bartlett J, Parfitt J). Comprehensive molecular characterization of papillary renal-cell carcinoma. N Engl J Med, 2016 Jan 14; 374 (2): 135-45   DOI: 10.1038/nature13385  PMID 26536169.
    85. Arifin A, Driman DK, Parfitt J. Liver Biopsy Crash Course. MedEdPORTAL, 2016 Jan 6; 10318, Available from: https://www.mededportal.org/publication/10318
    86. Poon AFY. Impacts and shortcomings of genetic clustering methods for infectious disease outbreaks. Virus Evolution. Volume 2, Issue 2, July 2016 DOI: 10.1093/ve/vew031

    87. Montoya V, Olmstead A, Tang P, Cook D, Janjua N, Grebely J, Jacka B, Poon AF, Krajden M. Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing. Infect Genet Evol, 329-37. DOI 10.1016/j.meegid.2016.06.015. PMID 27282472

    88. McCloskey RM, Liang RH, Poon AF. Reconstructing contact network parameters from viral phylogenies. Virus Evol. 2016 Oct 30;2(2):vew029. eCollection 2016. DOI: 10.1093/ve/vew029 PMID: 27818787
    89. Sweeney NP, Regan C, Liu J, Galleu A, Dazzi F, Lindemann D, Rupar CA, McClure MO.  Rapid and Efficient Stable Gene Transfer to Mesenchymal Stromal Cells Using a Modified Foamy Virus Vector.  Mol Ther. 2016 Aug 1; 24 (7): 1227-36.  DOI: 10.1038/mt.2016.91  PMID 27133965.

    90. Kelland E, Rupar CA, Prasad AN, Tay KY, Downie A, Prasad C. Response to: Letter to the Editor Regarding: The Expanding Phenotype of MELAS Caused by the m.3291 T > C tRNA Mutation E Kelland, C. A. Rupar, Asuri N. Prasad, K. Y. Tay, A. Downie and C. Prasad (1) by Josef Finsterer, MD, PhD [1], Sinda Zarrouk-Mahjoub, PhD [2] [1] Krankenanstalt Rudolfstiftung, Vienna [2] Genomics Platform, Pasteur Institute of Tunis, Tunisia. Mol Genet Metab Rep, 2016 Jul 15; 8: 41-2.  DOI: 10.1016/j.ymgmr.2016.07.002  PMID 27493879.
    91. Oud MM, Bonnard C, Mans DA, Altunoglu U, Tohari S, Ng AY, Eskin A, Lee H, Rupar CA, de Wagenaar NP, Wu KM, Lahiry P, Pazour GJ, Nelson SF, Hegele RA, Roepman R, Kayserili H, Venkatesh B, Siu VM, Reversade B, Arts HH.  A novel ICK mutation causes ciliary disruption and lethal endocrine-cerebro-osteodysplasia syndrome.  Cilia, 2016 Apr 11; 5: 8.  DOI: 10.1186/s13630-016-0029-1  PMID 27069622.

    92. Keilland E, Rupar CA, Prasad AN, Tay KY, Downie A, Prasad C.  The expanding phenotype of MELAS caused by the m.3291T > C mutation in the MT-TL1 gene.  Mol Genet Metab Rep, 2016 Feb 22; 6: 64-9.  DOI: 10.1016/j.ymgmr.2016.02.003  PMID 27014580.
    93. Kumar N, Rizek P, Sadikovic B, Adams PC, Jog M.  Movement Disorders Associated With Hemochromatosis.  Can J Neurol Sci. 2016 Nov;43(6):801-808.  DOI: 

      10.1017/cjn.2016.286  PMID: 27827297

    94. Lanktree MB, Sadikovic B, Waye JS, Levstik A, Lanktree BB, Yudin J, Crowther MA, Pare G, Adams PC.  Clinical evaluation of a hemochromatosis next-generation sequencing gene panel.  Eur J Haematol. 2016 Oct 18. doi: 10.1111/ejh.12820. [Epub ahead of print]  PMID: 27753142

    95. Sangle N, Baringer JR, Majersik J, DeWitt LD. CADASIL with Multiorgan Involvement: a Complete Autopsy Examination Report. Can J Neurol Sci, 2016 Jan 1; 43 (1): 202-5  DOI: 10.1017/cjn.2015.240  PMID 26138243.
    96. Agarwal AM, Nussenzveig RH, Reading NS, Patel JL, Sangle N, Salama ME, Prchal JT, Perkins SL, Yaish HM, Christensen RD.  Clinical utility of next-generation sequencing in the diagnosis of hereditary haemolytic anaemias.  Br J Haematol. 2016 Jun 12. DOI: 10.1111/bjh.14131 [Epub ahead of print]  PMID:  27292444

    97. Pang R, Merritt NH, Shkrum MJ, Tijssen JA.  Febrile Illness in an Infant With an Intracardiac Inflammatory Myofibroblastic Tumor.  Pediatrics. 2016 Feb;137(2):1-5  DOI:  10.1542/peds.2014-3544.  PMID:  26798044
    98. Shkrum, MJ, Kent, J. An Autopsy Checklist. A Monitor of Safety and Risk Management. Am J Forensic Med Pathol 2016, 37(3):152-157.

    99. Evetts AA, Shkrum MJ, Tugaleva E. Postmortem Body and Organ Measurements in Neonates and Infants: A Review of Reference Resources Used by Ontario Pathologists (Part 1). Am J Forensic Med Pathol. 2016 Sep;37(3):179-82. doi: 10.1097/PAF.0000000000000258. PMID 27438787
    100. Solh Z, Athale U, Arnold DM, Cook RJ, Foley R, Heddle NM. Transfusion-related alloimmunization in children: epidemiology and effects of chemotherapy. Vox Sang. 2016 Oct;111(3):299-307. doi: 10.1111/vox.12419. Epub 2016 May 27. PMID: 27231826.
    101. Solh Z, Chan AK, Heddle NM. Transfusion premedication practices among pediatric health care practitioners in Canada: results of a national survey. Transfusion. 2016 Sep;56(9):2296-302. doi: 10.1111/trf.13697. Epub 2016 Jun 16. PMID: 27312015.
    102. Solh Z, Taccone MS, Marin S, Athale U, Breakey VR. Neurological PRESentations in Sickle Cell Patients Are Not Always Stroke: A Review of Posterior Reversible Encephalopathy Syndrome in Sickle Cell Disease. Pediatr Blood Cancer. 2016 Jun;63(6):983-9. doi: 10.1002/pbc.25932. Epub 2016 Feb 12. Review. PMID:26871763.
    103. Solh Z, Breakey V, Murthy P, Smith JW, Arnold DM. Triplets with neonatal alloimmune thrombocytopenia due to antibodies against human platelet antigen 1a. Transfusion. 2016 May;56(5):1166-1170. doi: 10.1111/trf.13494. Epub 2016 Jan 26. PMID: 26813079.
    104. Schünemann HJ, Ventresca M, Crowther M, Briel M, Zhou Q, Garcia D, Lyman G, Noble S, Macbeth F, Griffiths G, DiNisio M, Iorio A, Beyene J, Mbuagbaw L, Neumann I, Van Es N, Brouwers M, Brozek J, Guyatt G, Levine M, Moll S, Santesso N, Streiff M, Baldeh T, Florez I, Gurunlu Alma O, Solh Z, Ageno W, Marcucci M, Bozas G, Zulian G, Maraveyas A, Lebeau B, Buller H, Evans J, McBane R, Bleker S, Pelzer U, Akl EA; IPDMA heparin use in cancer patients research group. Use of heparins in patients with cancer: individual participant data meta-analysis of randomised trials study protocol. BMJ Open. 2016 Apr 29;6(4):e010569. doi: 10.1136/bmjopen-2015-010569. Review. PubMed PMID: 27130164; PubMed Central PMCID: PMC4853971.
    105. Walsh GM, Shih AW, Solh Z, Golder M, Schubert P, Fearon M, Sheffield WP. Blood-Borne Pathogens: A Canadian Blood Services Centre for Innovation Symposium. Transfus Med Rev. 2016 Apr;30(2):53-68. doi: 10.1016/j.tmrv.2016.02.003. Epub 2016 Feb 23. PubMed PMID: 26962008; PubMed Central PMCID: PMC7126603.
    106. Kirstein, JM, Hague NM, McGowan PM, Tuck AB, Chambers AF. Primary melanoma tumor inhibits metastasis through alterations in systemic hemostasis.   J Mol Med (Berl).  Top of Form2016 Apr 6. [Epub ahead of print]  PMID:  27048169
    107. Walsh JC, Schaeffer DF, Kirsch R, Pollett A, Manzoni M, Riddell RH, Albarello L. Ileal 'carcinoid' tumours - small size belies deadly intent: high rate of nodal metastasis in tumours ≤1cm in size. Hum Pathol. 2016 Jun 17. pii: S0046-8177(16)30108-3. doi: 10.1016/j.humpath.2016.05.023. [Epub ahead of print].
    108. Goebel EA,  Walsh JC.  Heterotopic Bone in the Distal Esophagus.  Int J Surg Pathol. 2016 Feb 12 [epub ahead of print]  DOI:  10.1177/1066896916632299  PMID:  26873339
    109. Goebel EA, McCluggage WG, Walsh JC. Mitotically Active Sclerosing Stromal Tumor of the Ovary: Report of a Case Series With Parallels to Mitotically Active Cellular Fibroma. Int J Gynecol Pathol, 2016 May 4; Epub ahead of print.  DOI: 10.1097/PGP.0000000000000292  PMID 27149006.
    110. Goebel EA,  Walsh JC.  Omental cholelithiasis: a histologic correlation.  Canadian Journal of Pathology, letter to the editor 2016; 7(4):6
    111. Sarr O, Blake A, Thompson J, Zhao L, Rabicki K, Walsh JC, Welch I, Regnault TR. The differential effects of low birth weight and western diet consumption upon early life hepatic fibrosis development in guinea pig. J Physiol, 1753-1772, doi 10.1113/JP271777, 2016/03.
    112. Schaeffer DF, Walsh JC, Tyler AD, Ben-Bassat O, Silverberg MS, Riddell RH, Kirsch R. Intra-epithelial lymphocytosis is a frequent finding in biopsies from ileal pouch-anal anastomoses (IPAA). Hum Pathol  2016 Apr 7. 1753-1772 [epub ahead of print] DOI:  10.1016/j.humpath.2016.03.007 PMID:  27063473
    113. Shoker A, Xu Q, Lim HJ.   Differential Association Between Responder’s HLA-DR Phenotypes and HLD-DR Antibody Production in Patients Awaiting for Renal Transplantation; Analysis of UNOS Database. J Clin Exp Transplant 1:103. DOI: 10.4172/jcet.1000103

    114. Li Q, Johnston N, Zheng X, Wang H, Zhang X, Gao D, Min W. miR-28 modulates exhaustive differentiation of T cells through silencing programmed cell death-1 and regulating cytokine secretion. Oncotarget. 2016 Aug 16; 7(33):53735-53750. doi: 10.18632/oncotarget.10731.

    115. Siu KS, Zhang Y, Zheng X, Koropatnick J, Min WP .Non-Covalently Functionalized of Single-Walled Carbon Nanotubes by DSPE-PEG-PEI for SiRNA Delivery. Methods Mol Biol. 2016; 1364:151-63. doi: 10.1007/978-1-4939-3112-5_13.

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      Wang Z, Xu L, Hu Y, Huang Y, Zhang Y, Zheng X, Wang S, Wang Y, Yu Y, Zhang M, Yuan K, Min W. miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer. Sci Rep. 2016 May 9; 6:25602. doi: 10.1038/srep25602
    117. Wang H, Zhang X, Zheng X, Lan Z, Sh, J, Jiang J, Zwiep T, Li Q, Quan D, Zhang Z-X, Min W. Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways. Sci Rep. 2016 Sep 23;6:33869. doi: 10.1038/srep33869. PMID 27659428

    118. Liu Y, Zhang Y, Zheng X, Zhang X, Wang H, Li Q, Yuan K, Zhou N, Yu Y, Song N, Fu J, Min W. Gene silencing of indoleamine 2,3-dioxygenase 2 in melanoma cells induces apoptosis through the suppression of NAD+ and inhibits in vivo tumor growth. Oncotarget 2016 Apr 6. DOI: 10.18632/oncotarget.8617. [Epub ahead of print] PMID: 27058624
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2015 Publications

    1. Cybulski C, Lubinski J, Huzarski T, Lynch HT, Randall SA, Neuhausen SL, Senter L, Friedman S,  Ainsworth P, Singer C, Foulkes WD, Narod SA, Sun P, Kotsopoulos J.  Prospective evaluation of alcohol consumption and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers.  Breast Cancer Res Treat. 2015 Jun;151(2):435-41. doi: 10.1007/s10549-015-3393-4. PMID:  25935583. Epub 2015 May 3.
    2. Kotsopoulos J, Lubinski J, Neuhausen SL, Gronwald J, Lynch HT, Huzarski T, Demsky R, Foulkes WD, Senter L, Friedman S,  Ainsworth P, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. Weight gain after oophorectomy among women with a BRCA1 or BRCA2 mutation.  Womens Health (Lond Engl). 2015 Jul;11(4):453-9  DOI:  10.2217/WHE.15.4  PMID:  26258912
    3. Semple J, Metcalfe KA, Lubinski J, Huzarski T, Gronwald J, Armel S, Lynch HT, Karlan B, Foulkes W, Singer CF, Neuhausen SL, Eng C, Iqbal J, Narod SA, Hereditary Breast Cancer Clinical Study Group (incl. Ainsworth, P). Does the age of breast cancer diagnosis in first-degree relatives impact on the risk of breast cancer in BRCA1 and BRCA2 mutation carriers? Breast Cancer Res Treat, 2015 Nov 1; 154 (1): 163-9.   DOI: 10.1007/s10549-015-3596-8. PMID 26467043.
    4. Nikitina D, Chen Z, Vallis K, Poll A, Ainsworth P, Narod SA, Kotsopoulos J. Relationship between Caffeine and Levels of DNA Repair and Oxidative Stress in Women with and without a BRCA1 Mutation. J Nutrigenet Nutrigenomics, 2015 Jan 1; 8 (4-6): 174-84.  DOI: 10.1159/000439110. PMID 26670362.
    5. Alturkustani M, Mandzia J, Watling C, Cooper P, Bahakeen B, Leung A, Gulka I,  Howlett CHammond R.  CNPC: Acute myelopathy in a 68 year old male.  Can J Neurol Sci.  2015; 42: 466-471 DOI: 10.1017/cjn.2015.305
    6. Alturkustani M, Keith J, Hazrati LN, Rademakers R,  Ang LC.  Pathologic staging of white matter lesions in adult-onset leukoencephalopathy/leukodystrophy with axonal spheroids  J Neuropathol Exp Neurol. Top of Form2015 Mar;74(3):233-40  DOI:  10.1097/NEN.0000000000000168  PMID:  25668567
    7. Kertesz A, Finger E, Murrell J, Chertkow H,  Ang LC, Baker M, Ravenscroft T, Rademakers R, Muno, DG.  Progressive Supranuclear Palsy in a family with TDP-43 pathology.  Neurocase, Volume 21, Issue 2, 4 March 2015, Pages 178-184.  doi: 10.1080/13554794.2013.878729.
    8. Tong J,  Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ.  Low levels of astroglial markers in Parkinson's disease: relationship to α-synuclein accumulation.  Neurobiol Dis 2015 Jun 21;82:243-253  DOI:  10.1016/j.nbd.2015.06.010  PMID:  26102022
    9. Abuzgaia AM, Hardy DB,  Arany E. Regulation of postnatal pancreatic Pdx1 and downstream target genes after gestational exposure to protein restriction in rats. Reproduction (2015) 149 293–303. DOI: 10.1530/REP-14-0245 ISSN 1470–1626 (paper) 1741–7899 (online).
    10. Asfaha S, Hayakawa Y, Muley A, Stokes S, Graham, TA, Ericksen RE, Westphalen CB, vonBurstin J, Mastracci TL, Worthley DL, Guha C, Quante M, Rustgi AK, Wang TC.  Krt19(+)/Lgr5(-) Cells Are Radioresistant Cancer-Initiating Stem Cells in the Colon and Intestine.  J.Stem Volume 16, Issue 6, 4 June 2015, Pages 627-638  DOI:  10.1016/j.stem.2015.04.013.
    11. Tsimbiri, P.F., Moturi, W.N., Sawe, J., Henley, P. and  Bend, J.R. Health impact of pesticides on residents and horticultural workers in the Lake Naivasha Region, Kenya. Occupational Diseases and Environmental Medicine. 3: 24-34, 2015.  http://dx.doi.org/10.4236/odem.2015.32004
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    84. Rakovitch E, Nofech-Mozes S, Hanna W, Baehner FL, Saskin R, Butler SM,  Tuck A, Sengupta S, Elavathil S,  Jani PA, Bonin M, Chang MC, Robertson SJ, Slodkowska E, Fong C, Anderson JM, Jamshidian F,  Miller DP, Cherbavaz DB,  Shak S, Paszat L.  A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by beast-conserving surgery alone  Breast Cancer Res Treat. 2015; 152(2): 389–398.  DOI:  10.1007/s10549-015-3464-6  PMID:  4491104
    85. Anborgh P, Caria LBR, Chambers AF,  Tuck AB, Stitt LW,  Brackstone M  Role of plasma osteopontin as a biomarker in locally advanced breast cancer  Am J Transl Res  2015; 7(4): 723–732  PMID:  26064440
    86. Klein J, Kong I, Paszat L, Nofech-Mozes S, Hanna W, Thiruchelvam D, Narod SA, Saskin R, Done SJ, Miller N, Youngson B,  Tuck A, Sengupta S, Elavathil L, Jani PA, Slodkowska E, Bonin M, Rakovitch E.  Close or positive resection margins are not associated with an increased risk of chest wall recurrence in women with DCIS treated by mastectomy: a population-based analysis  Springerplus. 2015 Jul 10;4:335  DOI:  10.1186/s40064-015-1032-5  PMID:  26185737
    87. Sultan A, Goela A,  Tweedie E, Awan K, Lavi S.  Multimodality Imaging for Assessment of Coronary Embolus.  Can J Cardiol. Volume 31, Issue 3, 1 March 2015, Pages 364.e5-364.e7 DOI:  10.1016/j.cjca.2014.12.010  PMID:  25746026
    88. Sarr O, Blake A, Thompson J, Zhao L, Rabicki K, Walsh JC, Welch I, Regnault TR. The differential effects of low birth weight and western diet consumption upon early life hepatic fibrosis development in guinea pig. J Physiol 2015 Dec 10 DOI: 10.1113/JP271777. [Epub ahead of print] PMID: 26662996
    89. Zhang Q, Pocrnich C, Kurian A, Hahn AF, Howlett C, Shepherd J, Rizkalla K. Amyloid deposition in extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue: a clinicopathologic study of 5 cases. Pathol Res Pract 2015 Sep 5. [epub ahead of print] DOI: 10.1016/j.prp.2015.08.007 PMID: 26847730
    90. Maleki Vareki S, Chen D, Di Cresce C, Ferguson PJ, Figueredo R, Pampillo M, Rytelewski M, Vincent M, Min W, Zheng X, Koropatnick. IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells.  PLoS One. 2015 Nov 18; 10(11):e0143435.  doi: 10.1371/journal.pone.0143435. eCollection 2015. PMID: 26579709

2014 Publications

    1. Phelan CM, Iqbal J, Lynch HT, Lubinski J, Gronwald J, Moller P, Ghadirian P, Foulkes WD, Armel S, Eisen A, Neuhausen SL, Senter L, Singer CF, Ainsworth P, Kim-Sing C, Tung N, Llacuachaqui M, Chornokur G, Ping S, Narod SA, Hereditary Breast Cancer Study Group. Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study. Br J Cancer. 2014 Jan 21;110(2):530-4.530-4 doi:10.1038/bjc.2013.741. PMID24292448
    2. Kotsopoulos J, Lubinski J, Moller P, Lynch HT, Singer CF, Eng C, Neuhausen SL, Karlan B, Kim-Sing C, Huzarski T, Gronwald J, McCuaig J, Senter L, Tung N, Ghadirian P, Eisen A, Gilchrist D, Blum JL, Zakalik D, Pal T, Sun P, Narod SA, Hereditary Breast Cancer Clinical Study Group ( Ainsworth P, et al). Timing of oral contraceptive use and the risk of breast cancer in BRCA1 mutation carriers. Breast Cancer Res Treat579-86 doi:10.1007/s10549-013-2. PMID24458845
    3. Finch AP, Lubinski J, Møller P, Singer CF, Karlan B, Senter L, Rosen B, Maehle L, Ghadirian P, Cybulski C, Huzarski T, Eisen A, Foulkes WD, Kim-Sing C, Ainsworth P, Tung N, Lynch HT, Neuhausen S, Metcalfe KA, Thompson I, Murphy J, Sun P, Narod SA. Impact of Oophorectomy on Cancer Incidence and Mortality in Women With a BRCA1 or BRCA2 Mutation. J Clin Oncol1547-53 doi:10.1200/JCO.2013.53.  PMID24567435
    4. Kertesz A, Finger E, Murrell J, Chertkow H, Ang LC, Baker M, Ravenscroft T, Rademakers R, Munoz DG. Progressive Supranuclear Palsy in a family with TDP-43 pathology. Neurocase doi:10.1080/13554794.201. PMID24479957
    5. Tong J, Fitzmaurice P, Furukawa Y, Schmunk GA, Wickham DJ, Ang LC, Sherwin A, McCluskey T, Boileau I, Kish SJ. Is brain gliosis a characteristic of chronic methamphetamine use in the human? Neurobiol Dis 107-18 doi:10.1016/j.nbd.2014.0. PMID24704312
    6. Lin AW, Das S, Fraser JA, Ang LC, Florendo-Cumbermack A, Jenkins ME, Tay KY. Emergence of Primary CNS Lymphoma in a Patient with Findings of CLIPPERS. Can J Neurol Sci. 2014 Jul;41(4):528-9.528-9.  PMID24878484
    7. Henley P, Lowthers M, Koren G, Fedha PT, Russell E, VanUum S, Arya S, Darnell R, Creed IF, Trick CG, Bend JR. Cultural and socio-economic conditions as factors contributing to chronic stress in sub-Saharan African communities. Can J Physiol Pharmacol. 92:725-32, 2014.
    8. Xiao J, Li J, Cai L, Chakrabarti S, Li X. Cytokines and diabetes research. Journal of Diabetes Research, Volume 2014, 2014, Article number 920613 PMID24551859
    9. Mortuza R, Chakrabarti S. Glucose-induced cell signaling in the pathogenesis of diabetic cardiomyopathy. Heart Fail Rev, 75-86 doi:10.1007/s10741-013-9. PMID23430126
    10. Chen S, Puthanveetil P, Feng B, Matkovich SJ, Dorn GW, Chakrabarti S. Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes. Journal of Cellular and Molecular MedicineVolume 18, Issue 3, March 2014, Pages 415-421. PMID24428157
    11. Feng B, Cao Y, Chen S, Ruiz M, Chakrabarti S. miRNA-1 regulates endothelin-1 in diabetes. Life Sci2014 Mar 7;98(1):18-23, doi:10.1016/j.lfs.2013.12.199. Epub 2014 Jan 3.  PMID24394957
    12. Cong W, Zhao T, Zhu Z, Huang B, Ma W, Wang Y, Tan Y, Chakrabarti S, Li X, Jin L, Cai L. Metallothionein prevents cardiac pathological changes in diabetes by modulating nitration and inactivation of cardiac ATP synthase. J Nutr Biochem 463-74, doi:10.1016/j.jnutbio.20. PMID24629910
    13. Beaton MD, Chakrabarti S, Adams PC. Inflammation is not the cause of an elevated serum ferritin in non-alcoholic fatty liver disease. Ann Hepatol353-6. PMID24756010
    14. Mortuza R, Feng B, Chakrabarti S. miR-195 regulates SIRT1-mediated changes in diabetic retinopathy. Diabetologia1037-46, doi:10.1007/s00125-014-3. PMID24570140.
    15. Zhao YZ, Tian XQ, Zhang M, Cai L, Ru A, Shen XT, Jiang X, Jin RR, Zheng L, Hawkins K, Chakrabarti S, Li XK, Lin Q, Yu WZ, Ge S, Lu CT, Wong HL. Functional and pathological improvements of the hearts in diabetes model by the combined therapy of bFGF-loaded nanoparticles with ultrasound-targeted microbubble destruction. J Control Release. 2014 Jul 28;186:22-31. doi:10.1016/j.jconrel.2014.04.054. Epub 2014 May 9. PMID24815422.
    16. Cao Y, Feng B, Chen S, Chu Y, Chakrabarti S. Mechanisms of endothelial to mesenchymal transition in the retina in diabetes. Investigative Ophthalmology Visual ScienceInvest Ophthalmol Vis Sci. 2014 Oct 21;55(11):7321-31. doi:10.1167/iovs.14-15167. PMID25335984.
    17. Zuo Y, Wu Y, Wehrli B, Chakrabarti S, Chakraborty C. Modulation of ERK5 Is a novel mechanism by which CDc42 Regulates Migration of Breast Cancer Cells. Journal Cell Biochemistry. doi:10.1002/jcb.24950. 
    18. Zeng C, Zhong P, Zhao Y, Kanchana K, Zhang Y, Khan ZA, Chakrabarti S, Wu L, Wang J, Liang G. Curcumin protects hearts from FFA-induced injury by activating Nrf2 and inactivating NF-κB both in vitro and in vivo. J Mol Cell Cardiol. 2015 ;79:1-12. Epub 2014 Oct 16
    19. Puthanveetil P, Thomas AA, Chakrabarti S. microRNAs in diabetes - are they perpetrators in disguise or just epiphenomena? Non-coding RNAs in Endocrinology. Volume 1, Issue 1, ISSN (Online) 2300-4258. doi:10.2478/micrnado-2014-0002, September 2014.
    20. Beaucage KL, Xiao A, Pollmann SI, Grol MW, Holdsworth DW, Sims SM, Darling MR, Dixon SJ. Loss of P2X7 nucleotide receptor function leads to abnormal fat distribution in mice. Purinergic Signalling 2014 Jun;10(2):291-304. doi:10.1007/s11302-013-9388-x. Epub 2013 Nov 13.  PMID24222214.
    21. Poon R, Su N, Ching V, Darling M, Grushka M. Reduction in unstimulated salivary flow rate in burning mouth syndrome. Br Dent J. 2014 Oct 10;217(7):E14. doi:10.1038/sj.bdj.2014.884. PMID25303607.
    22. Wilson A,  Delport J, Ponich T. Candida glabrata esophagitis: Are we seeing the emergence of a new azole-resistant pathogen?  International Journal of Microbiology. 2014;2014:371631. doi: 10.1155/2014/371631. Epub 2014 Dec 3
    23. Delport JA, John MA, Conkey B, MacDonald K, Lannigan R. Comparison of Direct Identification of Bacteria from VersaTrek Blood Culture Bottles Using a Seven Present Saponin Extraction Method and SepsiTyper by the Bruker MALDI-TOF. Int J Infect Dis. 2014 Apr; 21 (S1): 371.  DOI:  10.1016/j.ijid.2014.03.1186
    24. Anantha RV, Jegatheswaran J, Pepe DL, Priestap F, Delport J, Haeryfar SM, McCormick JK, Mele T. Risk Factors for Mortality Among Canadian Patients with Staphylococcus aureus Bacteremia: A Single Centre Retrospective Cohort Study. CMAJ Open. 2014 Oct: 2(4): E352-359. DOI: 10.9778/ cmajo.20140018.  eCollection 2014 Oct.  PMID:25553328
    25. Stuart JI, Delport J, Lannigan R, Zahariadis G. Determination of real-time polymerase chain reaction uncertainty of measurement using replicate analysis and a graphical user interface with Fieller's theorem. Can J Infect Dis Med Microbiol. 2014 Jul;25(4):207-10. PMID: 25285125
    26. Castonguay MC, Li-Chang HH, Driman DK. Venous invasion in oesophageal adenocarcinoma: enhanced detection using elastic stain and association with adverse histological features and clinical outcomes. Histopathology 693-700, doi:10.1111/his.12308. PMID24117900.
    27. Osmond A, Li-Chang H, Kirsch R, Divaris D, Falck V, Liu DF, Marginean C, Newell K, Parfitt J, Rudrick B, Sapp H, Smith S, Walsh J, Wasty F, Driman DK. Interobserver variability in assessing dysplasia and architecture in colorectal adenomas: a multicentre Canadian study. J Clin Pathol, doi:10.1136/jclinpath-20. PMID25004943.
    28. Rajakumar C, Vilos GA, Vilos AG, Marks JL, Ettler HC, Pautler SS. Combined Transurethral and Laparoscopic Partial Cystectomy and Robotically Assisted Bladder Repair for the Treatment of Bladder Endocervicosis: Case Report and Review of the Literature. J Obstet Gynaecol Can141-145. PMID24518913.
    29. Toro CM, Janvier J, Zhang K, Fonseca K, Gregson D, Church D, Laupland K, Rabin H, Elsayed S, Conly J. Community-associated methicillin-resistant Staphylococcus aureus necrotizing pneumonia without evidence of antecedent viral upper respiratory infection. Can J Infect Dis Med Microbiol. 2014 May;25(3):e76-82. DOI: 10.1155/2014/952603 PMID: 25285117
    30. Girgis H, Masui O, White NM, Scorilas A, Rotondo F, Seivwright A, Gabril M, Filter ER, Girgis AH, Bjarnason GA, Jewett MA, Evans A, Al-Haddad S, Siu KM, Yousef GM. Lactate Dehydrogenase A is a potential prognostic marker in clear cell renal cell carcinoma. Mol Cancer101 doi:10.1186/1476-4598-13. PMID24885701.
    31. Canadian Association of Pathologists Telepathology Guidelines Committee, Bernard C, Chandrakanth SA, Cornell IS, Dalton J, Evans A, Garcia BM, Godin C, Godlewski M, Jansen GH, Kabani A, Louahlia S, Manning L, Maung R, Moore L, Philley J, Slatnik J, Srigley J, Thibault A, Picard DD, Cracower H, Tetu B. Guidelines from the Canadian Association of Pathologists for establishing a telepathology service for anatomic pathology using whole-slide imaging. J Pathol Inform15, doi:10.4103/2153-3539.129455. eCollection 2014. PMID24843826.
    32. Wang H, Zhang Z, Tian W, Liu T, Han H, Fu Q, Garcia B, Li X. Memory T Cells Mediate Cardiac Allograft Vasculopathy and are Inactivated by Anti-OX40L Monoclonal Antibody. Cardiovasc Drugs Ther.2014; 28: 115-22. doi:10.1007/s10557-013-6502-9. PMID24254032.
    33. Palmer TD, Martínez CH, Vasquez C, Hebron KE, Jones-Paris C, Arnold SA, Chan SM, Chalasani V, Gomez-Lemus JA, Williams AK, Chin JL, Giannico GA, Ketova T, Lewis JD, Zijlstra A. Integrin-free tetraspanin CD151 can inhibit tumor cell motility upon clustering and is a clinical indicator of prostate cancer progression. Cancer Res173-87 doi:10.1158/0008-5472.CA. PMID24220242.
    34. Lau A, Khan K, Pavlosky A, Yin Z, Huang X, Haig A, Liu W, Singh B, Zhang ZX, Jevnikar AM. Serine Protease Inhibitor-6 Inhibits Granzyme B-Mediated Injury of Renal Tubular Cells and Promotes Renal Allograft Survival. Transplantation doi:10.1097/TP.000000000. PMID24918613.
    35. Lau A, Wang S, Liu W, Haig A, Zhang ZX, Jevnikar AM. Glycyrrhizic Acid Ameliorates HMGB1-Mediated Cell Death and Inflammation after Renal Ischemia Reperfusion Injury. Am J Nephrol84-95 doi:10.1159/000364908. PMID25059568.
    36. Rizek P, Cheung C, McLachlan RS, Hayman-Abello B, Lee DH, Hammond RR, Mirsattari SM. Childhood-onset nonprogressive chronic encephalitis. Epilepsy Behav. 2014 Feb;31:85-90 doi:10.1016/j.yebeh.2013. PMID24368410.
    37. Piorkowska K, Thompson JA, Nygard K, Matushewski B, Hammond RR, Richardson BS.   Synaptic Development and Neuronal Myelination are Altered with Growth Restriction in Fetal Guinea Pigs, Dev Neurosci, 2014;36(6):465-76. DOI: 10.1159/000363696. Epub 2014 Sep 26  PMID: 25277216
    38. Haust, MD, Gilber-Barness EF.  Founders of Pediatric Pathology: Remembering Dr Marie Valdes-Dapena.  Pediatric and Developmental Pathology 17, 165-168, 2014 doi: 10.2350/14-02-1442-PB.1
    39. Weinreb I, Piscuoglio S, Martelotto LG, Waggott D, Ng CK, Perez-Ordonez B, Harding NJ, Alfaro J, Chu KC, Viale A, Fusco N, da Cruz Paula A, Marchio C, Sakr RA, Lim R, Thompson LD, Chiosea SI, Seethala RR, Skalova A, Stelow EB, Fonseca I, Assaad A, How C, Wang J, de Borja R, Chan-Seng-Yue M, Howlett CJ, Nichols AC, Wen YH, Katabi N, Buchner N, Mullen L, Kislinger T, Wouters BG, Liu FF, Norton L, McPherson JD, Rubin BP, Clarke BA, Weigelt B, Boutros PC, Reis-Filho JS. Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands. Nat Genet. 2014 Nov;46(11):1166-9 doi:10.1038/ng.3096. PMID25240283.
    40. Wong H, Watt C, Elsayed S, John M, Johnson G, Katz K, Krajden S, Lee C, Mazzulli T, Ostrowska K, Richardson D, Toye B, Vermeiren C, Yamamura D, Simor AE. Characterization of methicillin-resistant Staphylococcus aureus isolates from patients with persistent or recurrent bacteremia. Can J Infect Dis Med Microbiol. 2014;25:83-6. DOI: 10.1155/2014/853482 PMID: 24855475
    41. Lutz K, Hayward V, Joseph M, Wong E, Temple-Oberle C. Current biopsy practices for suspected melanomas: A Survey of Family Physicians in Southwestern Ontario. The Canadian Journal of Plastic Surgery, 22(3), 175-178.
    42. Kum JJY, Khan ZA. Propranolol inhibits growth of hemangioma-initiating cells but does not induce apoptosis. Pediatr Res75: 381-388, 2014 doi:10.1038/pr.2013.231. Epub 2013 Dec 2. PMID24296797.
    43. Keats EC, Dominguez JM, Grant MB, Khan ZA. Switch from canonical to noncanonical Wnt signaling mediates high glucose-induced adipogenesis. Stem Cells32: 1649–1660, 2014 doi: 10.1002/stem.1659.  PMID24496952.
    44. Piccinin MA, Khan ZA. Pathophysiological role of enhanced bone marrow adipogenesis in diabetic complications. Adipocyte 3; 14-23, 2014 doi:10.4161/adip.32215.
    45. Cutz JC1, Craddock KJ, Torlakovic E, Brandao G, Carter RF, Bigras G, Deschenes J, Izevbaye I, Xu Z, Greer W, Yatabe Y, Ionescu D, Karsan A, Jung S, Fraser RS, Blumenkrantz M, Lavoie J, Fortin F, Bojarski A, Côté GB, van den Berghe JA, Rashid-Kolvear F, Trotter M, Sekhon HS, Albadine R, Tran-Thanh D, Gorska I, Knoll JH, Xu J, Blencowe B, Iafrate AJ, Hwang DM, Pintilie M, Gaspo R, Couture C, Tsao MS. Canadian Anaplastic Lymphoma Kinase Study: A Model for multicenter standardization and optimization of ALK testing in lung cancer. J Thoracic Oncology 9(9):1255-1263 doi:10.1097/JTO.0000000000000239  PMID25122422.
    46. Rogan PK, Li Y, Wickramasinghe A, Subasinghe A, Caminsky N, Khan W, Samarabandu J, Wilkins R, Flegal F, Knoll JH. Automating dicentric chromosome detection from cytogenetic biodosimetry data. Radiat Prot Dosimetry2014 Jun;159(1-4):95-104 doi:10.1093/rpd/ncu133. Epub 2014 Apr 21. PMID24757176.
    47. Khan WA, Rogan PK, Knoll JH

      Localized, non-random differences in chromatin accessibility between homologous metaphase chromosomes. 

      Mol Cytogenet. 2014 Nov 19;7(1):70. doi: 10.1186/s13039-014-0070-y. eCollection 2014. PMID: 25520753

    48. Owrangi AM, Lannigan R, Simonovic SP. Interaction between land-use change, flooding and human health in Metro Vancouver, Canada. Natural Hazards, Volume 72, Issue 2, June 2014, Pages 1219-1230
    49. Cancer Genome Atlas Research Network (affiliated with Ontario Tumour Bank: Bartlett JMS, Kodeeswara S, Parfitt J, Sekhon H, Albert M). Comprehensive molecular profiling of lung adenocarcinoma. Nature543-50 doi:10.1038/nature13385. PMID25079552.
    50. Sy K, Parfitt J, Marginean C, Riddell RH, Streutker CJ. Inflammatory pseudotumours of the esophagus. Histopathology. 2014 Nov 13. doi:10.1111/his.12615. [Epub ahead of print]. PMID25393329.
    51. Farhan SM, Wang J, Robinson JF, Lahiry P, Siu VM, Prasad C, Kronick JB, Ramsay DA, Rupar CA, Hegele RA. Exome sequencing identifies NFS1 deficiency in a novel Fe-S cluster disease, infantile mitochondrial complex II/III deficiency. Mol Genet Genomic Med 73-80 doi:10.1002/mgg3.46. PMID24498631.
    52. Prasad M, Narayan B, Prasad AN, Rupar CA, Levin S, Kronick J, Ramsay D, Tay KY, Prasad C. MELAS: A Multigenerational Impact of the MTTL1 A3243G MELAS Mutation. Can J Neurol Sci. 2014 Mar;41(2):210-9. PMID24534033.
    53. Cohen MC, Ramsay DA. "Shaken baby syndrome" and forensic pathology. Forensic Sci Med Pathol244-5 doi:10.1007/s12024-013-9. PMID24464795.
    54. Bell K, Hodgson N, Levine M, Sadikovic B, Zbuk K (2014) Double heterozygosity for germline mutations in BRCA1 and p53 in a woman with early onset breast cancer. Breast Cancer Res Treat 146: 447-450 DOI: 10.1007/s10549-014-3011-x PMID: 24916180
    55. Cervigne NK, Machado J, Goswami RS, Sadikovic B, Bradley G, Perez-Ordonez B, Galloni NN, Gilbert R, Gullane P, Irish JC, Jurisica I, Reis PP, Kamel-Reid S (2014) Recurrent genomic alterations in sequential progressive leukoplakia and oral cancer: drivers of oral tumorigenesis? Hum Mol Genet 23: 2618-2628. DOI: 10.1093/hmg/ddt657  PMID: 24403051
    56. Mahadevan S, Wen S, Wan YW, Peng HH, Otta S, Liu Z, Iacovino M, Mahen EM, Kyba M, Sadikovic B, Van den Veyver IB (2014) NLRP7 affects trophoblast lineage differentiation, binds to overexpressed YY1 and alters CpG methylation. Hum Mol Genet 23: 706-716. DOI: 10.1093/hmg/ddt457  PMID: 24105472
    57. Sadikovic B, Pare G (2014) Genomics and epigenomics in pediatric oncology and clinical laboratory genetics. Clin Biochem 47: 731-732.  DOI: 10.1016/j.clinbiochem.2014.05.033 PMID: 24858242
    58. Sadikovic B, Fernandes P, Zhang VW, Ward PA, Miloslavskaya I, Rhead W, Rosenbaum R, Gin R, Roa B, Fang P (2014) Mutation Update for UBE3A variants in Angelman syndrome. Hum Mutat 35: 1407-1417.  DOI: 10.1002/humu.22687  PMID: 25212744
    59. Sangle NA, Schmidt RL, Patel JL, Jeffrey Medeiros L, Agarwal AM, Perkins SL, Salama ME. Optimized immunohistochemical panel to differentiate myeloid sarcoma from blastic plasmacytoid dendritic cell neoplasm. Mod Pathol.2014 Aug;27(8):1137-43. doi:10.1038/modpathol.2013.238. Epub 2014 Jan 3. PMID24390220.
    60. Layfield LJ, Schmidt RL, Sangle N, Crim JR. Diagnostic accuracy and clinical utility of biopsy in musculoskeletal lesions: a comparison of fine-needle aspiration, core, and open biopsy techniques. Diagn Cytopathol 2014 Jun;42(6):476-86. doi:10.1002/dc.23005. Epub 2014 Mar 19. PMID24644128.
    61. Jacques R, Kogon S, Shkrum M. An experimental model of tool mark striations by a serrated blade in human soft tissues. Am J Forensic Med Pathol59-61 doi:10.1097/PAF.00000000. PMID24457587.
    62. Bramwell VH, Tuck AB, Chapman JA, Anborgh PH, Postenka CO, Al-Katib W, Shepherd LE, Han L, Wilson CF, Pritchard KI, Pollak MN, Chambers AF. Assessment of osteopontin in early breast cancer: correlative study in a randomised clinical trial. Breast Cancer ResR8 doi:10.1186/bcr3600. PMID24451146.
    63. Fok TC, Lapointe H, Tuck AB, Chambers AF, Jackson-Boeters L, Daley TD, Darling MR. Expression and localization of osteopontin, homing cell adhesion molecule/CD44, and integrin αvβ3 in mucoepidermoid carcinoma and acinic cell adenocarcinoma of salivary gland origin. Oral Surg Oral Med Oral Pathol Oral Radiol 320-9 doi:10.1016/j.oooo.2014. PMID25151586.
    64. MacMillan CD, Leong HS, Dales DW, Robertson AE, Lewis JD, Chambers AF, Tuck AB. Stage of breast cancer progression influences cellular response to activation of the WNT/planar cell polarity pathway. Sci Rep6315 doi:10.1038/srep06315. PMID25204426.
    65. Lalani N, Paszat L, Sutradhar R, Thiruchelvam D, Nofech-Mozes S, Hanna W, Slodkowska E, Done SJ, Miller N, Youngson B, Tuck A, Sengupta S, Elavathil L, Chang MC, Jani PA, Bonin M, Rakovitch E. Long-term Outcomes of Hypofractionation Versus Conventional Radiation Therapy After Breast-Conserving Surgery for Ductal Carcinoma In Situ of the Breast. Int J Radiat Oncol Biol Phys doi:10.1016/j.ijrobp.201. PMID25220719.
    66. MacMillan CD, Leong HS, Dales DW, Robertson AE, Lewis JD, Chambers AF, Tuck AB. Stage of Breast Cancer Progression Influences Cellular Response to Activation of the WNT/Planar Cell Polarity Pathway. Scientific Reports, 4 : 6315 doi:10.1038/srep06315.
    67. O'Connor K, Walsh JC, Schaeffer DF.Combined hepatocellular-cholangiocarcinoma (cHCC-CC): a distinct entity. Ann Hepatol. 2014 May-Jun;13(3):317-22. PMID24756005.
    68. Schaeffer DF, Walsh JC, Kirsch R, Waterman M, Silverberg MS, Riddell RH.  Distinctive histopathologic phenotype in resection specimens from patients with Crohn's disease receiving anti-TNF-α therapy.  Hum Pathol. 2014 Sep;45(9):1928-35. DOI: 10.1016/j.humpath.2014.05.016. [Epub 2014 Jun 12.]  PMID: 25022570
    69. Ben-Bassat O, Tyler AD, Xu W, Kirsch R, Schaeffer DF, Walsh J, Steinhart AH, Greenberg GR, Cohen Z, Silverberg MS, McLeod RS.  Ileal pouch symptoms do not correlate with inflammation of the pouch.  Clin Gastroenterol Hepatol. 2014 May;12(5):831-837.e2. DOI: 10.1016/j.cgh.2013.09.027. [Epub 2013 Sep 27.]  PMID: 24075890
    70. Dowthwaite S, Szeto C, Wehrli B, Daley T, Whelan F, Franklin J, Nichols A, Yoo J, Fung K. Contact endoscopy as a novel technique in the detection and diagnosis of oral cavity and oropharyngeal mucosal lesions in the head and neck. J Laryngol Otol1-6 doi:10.1017/S00222151130. PMID24460932.
    71. Zuo Y, Wu Y, Wehrli B, Chakrabarti S, Chakraborty C. Modulation of ERK5 Is a Novel Mechanism by Which Cdc42 Regulates Migration of Breast Cancer Cells. J Cell Biochem doi:10.1002/jcb.24950. PMID25160664.
    72. Yeh DH, Wong J, Hoffbauer S, Wehrli B, Sommer D, Rotenberg BW. The utility of routine polyp histopathology after endoscopic sinus surgery. Int Forum Allergy Rhinol doi:10.1002/alr.21378.  PMID25142311.
    73. Zhang W, Xu X, Kao R, Mele T, Kvietys P, Martin CM, Rui T.  Cardiac fibroblasts contribute to myocardial dysfunction in mice with sepsis: the role of NLRP3 inflammasome activation. PLoS ONE 9(9): e107639. doi:10.1371/journal.pone.0107639
    74. Zhang X, Liu Y, Zhang G, Shi J, Zhang X, Zheng X, Jiang AT, Zhang ZX, Johnston N, Siu KS, Chen R, Lian D, Koos D, Quan D, Min WP. Synergic silencing of costimulatory molecules prevents cardiac allograft rejection. J Transl Med. 2014 May 22;12:142. doi: 10.1186/1479-5876-12-142.
    75. Chen D, Koropatnick J, Jiang N, Zheng X, Zhang X, Wang H, Yuan K,Siu KS, Shunnar A, Way C, Min WP. Targeted siRNA Silencing of Indoleamine 2, 3-Dioxygenase in Antigen-presenting Cells Using Mannose-conjugated Liposomes: A Novel Strategy for Treatment of Melanoma. J Immunother. 2014 Feb-Mar;37(2):123-34.
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