Igor Karp, PhD

Dr. Igor Karp

Associate Professor and Undergraduate Chair
Kresge Building K214
phone: 519.661.2111 ext: 86272
e-mail: ikarp@uwo.ca


  • Department of Epidemiology and Biostatistics

Research Cluster Membership

Research Interests

  • Theoretical epidemiology
  • Pharmacoepidemiology
  • Prognostic modeling
  • Applied clinical research
  • Cancer epidemiology
  • Cardiovascular disease epidemiology
  • Development of expert systems for medicine
  • Knowledge-base of medicine


  • MD Pediatrics
  • MPH Epidemiology
  • PhD Epidemiology

Publications (selected)

  • Karp I, Miettinen OS. On the essentials of etiological research for preventive medicine. European Journal of Epidemiology 2014; 29:455-457.
  • Karp I, Manganas A, Sylvestre MP, Ho A, Roger E, Duquette P. Does pregnancy alter the long-term course of multiple sclerosis? Annals of Epidemiology 2014; 24:504-508.e2.
  • Siemiatycki J, Karp I, Sylvestre MP, Pintos J. Estimating the proportion of lung cancer cases legally attributable to smoking: A novel approach for class actions against tobacco industries. American Journal of Public Health 2014; 12:e1-e7.
  • Karp I. RE: Estimating the relative risk in cohort studies and clinical trials of common outcomes. [Letter] American Journal of Epidemiology 2014; 179:1034-135.
  • Karp I. Confounding of incidence density ratio in case-control studies. Epidemiology 2013; 24:627.
  • Karp I. Irrelevance of non-collapsibility in case-control studies. Epidemiology 2013; 24:173-174.
  • Karp I, Abrahamowicz M, Fortin PR, Pilote L, Neville C, Pineau CA, Esdaile JM. Longitudinal evolution of coronary heart disease risk in systemic lupus erythematosus. Journal of Rheumatology 2012; 39:968-973.
  • Pilote L, Karp I. GENESIS-PRAXY (GENdEr and Sex determInantS of cardiovascular disease: from bench to beyond – Premature Acute Coronary SYndrome). American Heart Journal 2012; 163:741-746.e2.
  • Gilbert L, Basso O, Sampalis J, Karp I, Martins C, Feng J, et al. Assessment of symptomatic women for early diagnosis of ovarian cancer: Results from the prospective DOvE pilot project. Lancet Oncology 2012; 13:285-291.
  • Karp I, Paradis G, Lambert M, Dugas E, O’Loughlin J. A prognostic tool to identify adolescents at high risk of becoming daily smokers. BMC Pediatrics 2011; 11:70. doi:10.1186/1471-2431-11-70.
  • Thanassoulis G, Karp I, Humphries K, Tu J, Eisenberg MJ, Pilote L. Impact of restrictive prescription plans on the use of drugs and mortality in patients with heart failure. Circulation: Cardiovascular Quality and Outcomes 2009; 2:484-490.
  • O’Loughlin J, Karp I, Koulis T, Paradis G, DiFranza J. Determinants of first puff and daily cigarette smoking in adolescents. American Journal of Epidemiology 2009; 170:585-597.
  • Karp I, Behlouli H, Lelorier J, Pilote L. Statins and cancer risk. American Journal of Medicine 2008; 121:302-309.
  • O’Loughlin J, Karp I, Henderson M, Gray-Donald K. Does cigarette use influence adiposity or height in adolescents? Annals of Epidemiology 2008; 18:395-402.
  • Karp I, Abrahamowicz M, Fortin P, Pilote L, Neville C, Pineau C, Esdaile J. Recent corticosteroid use and recent disease activity: are they independent determinants of coronary heart disease risk factors in systemic lupus erythematosus? Arthritis Care and Research 2008; 59:169-175.
  • Karp I, Topol E, Pilote L. Population attributable fraction: its implications for genetic epidemiology and illness prevention. American Heart Journal 2007; 154:607-609.
  • Karp I, Chen SF, Pilote L. Sex differences in the effectiveness of statins in patients after myocardial infarction. Canadian Medical Association Journal, 2007; 176:333-338.
  • Karp I, O'Loughlin J, Hanley J, Tyndale R, Paradis G. Risk factors for nicotine dependence in adolescent smokers. Tobacco Control 2006; 15:199-204.
  • Karp I, O'Loughlin J, Paradis G, Hanley J, DiFranza J. Smoking trajectories of novice smokers in a longitudinal study of tobacco use. Annals of Epidemiology 2005; 15:445-452.
  • Karp I, Abrahamowicz M, Bartlett G, Pilote L. Updated risk factor values improve the ability of the multivariable risk score to predict coronary heart disease. American Journal of Epidemiology 2004; 160:707-716.