Derek W. Cool, MD, PhD, FRCPC


Associate Professor
London Health Sciences Centre, Victoria Hospital
Depts of Medical Imaging, Oncology & Medical Imaging
Associate Scientist, Lawson Research Institute

Dr. Derek Cool is a vascular and interventional radiologist who joined the Department of Medical Imaging in July 2017. He completed his medical training at Western University in 2011 as part of the combined MD/PhD program. After completing the Diagnostic Radiology residency program at Western University in 2016, he completed the Vascular and Interventional Radiology Fellowship in 2017 at the University Health Network (UHN)/Mt. Sinai hospitals in Toronto, Ontario. Prior to his medical education, Dr. Cool attended the University of North Carolina, Chapel Hill as a Morehead-Cain scholar, earning his Bachelor of Science degree in 2003.

Dr. Cool’s clinical and research interests include interventional oncology, with particular interest in genitourinary interventions and enhancing ultrasound-guided interventions. Dr. Cool has numerous peer-reviewed publications and scientific presentations at national and international meetings. In 2024, he joined the Editorial board for the Journal of Vascular and Interventional Radiology (JVIR) as an Associate Editor.

Dr. Cool’s research highlights include developing a 3-dimensional ultrasound system to improve the accuracy of ultrasound-guided liver and renal ablation. He also was lead-PI for the first-in-human clinical trial of the percutaneous ultrasound gastrostomy (PUG) technique for gastrostomy-tube insertion under ultrasound alone. Finally, his PhD research work developing a 3D transrectal ultrasound (TRUS) system to guide prostate biopsy procedures resulted in a commercially available system used clinically for MRI-TRUS fusion biopsy. Dr. Cool’s current research interests are focused on continued development of 3-dimensional ultrasound technology and improving IR therapies for renal cell carcinoma.

Clinical interests: Genitourinary and Oncology interventions – e.g. Cancer ablation and endovascular therapy, prostate embolization for BPH, and ureteric interventions.

Research interests: Renal cell carcinoma ablation and endovascular therapy, Medical device design, Genitourinary interventions, 3D Ultrasound, Image fusion technology to map pre-operative to intra-operative images to enhance minimally-invasive therapies.