Translational Immuno-Oncology Research Group

Immuno-Oncology has changed cancer care around the world in the last decade and is the fastest growing field in Oncology.

Immunotherapy is now the 4th arm of cancer treatment beyond surgery, chemotherapy, and radiotherapy, and is poised to transform the way clinicians manage and treat cancer patients. This research group brings together the enormous clinical and scientific expertise in cancer immunology, cancer immunotherapy and cancer immuno-imaging across London.

The Immuno-Oncology research will have an impact on improving our understanding of the roles the immune system plays in cancer to new ways to boost the immune system to treat cancer. Our group is building a pipeline of research projects across the Tumor Immunology (T-cells, Dendritic Cells (DCs), Macrophages), Cancer Immunotherapy (Checkpoint Inhibitors (ICIs), Gut Microbiome, Cell-Based Immunotherapies, Radionuclide Immunotherapy, Superantigen Immunotherapy) and Cancer Immuno-Imaging (Positron Emission Tomography (PET), Magnetic Resonance Imaging (MRI) and Magnetic Particle Imaging (MPI), Optical Imaging) fields of research. 

The Translational Immuno-Oncology Research Group will build on the existing strengths that London has to offer. The Schulich School of Medicine & Dentistry at Western University has formed a partnership with the London Health Sciences Centre (LHSC) which houses The London Regional Cancer Program (LRCP). The LRCP serves the cancer patients of southwestern Ontario with clinicians and trainees from Schulich. LHSC is also home to LHSC's Cancer Research Laboratory Program (CRLP) and the Gerald C. Baines Clinical Trial Unit (Baines) where clinicians researchers and basic scientists work together to treat cancer patients and advance patient clinical trials. 

Western Research, an arm of Western University has formed a partnership centre encompassing Robarts Research Institute, Lawson Health Research Institute, Western's Department of Medical Imaging, The School of Biomedical Engineering, and the Schulich School of Medicine & DentistryThe Biomedical Imaging Research Centre (BIRC) encompasses London-wide imaging and its researchers. Its integrated program is the most successful in Canada and ranks among the top 5 in the world. 

The Translational Immuno-Oncology Research Group have access to the one-of-a-kind Imaging Pathogens for Knowledge Translation (ImPaKT) Facility. This facility houses state-of-the-art in vivo small animal imaging modalities included a 3T PET/MRI, an optical /CT hybrid scanner, and a multiphoton microscope.

The group hosts monthly seminars focusing on learning about the breadth of immuno-oncology research being performed across the city, stimulate new ideas, collaboration opportunities highlight recent successes and discuss funding opportunitites. The group also hosts a weekly Immuno-Oncology journal club and an annual immuno-oncology symposium in February with national and international guest speakers. For more information and/or to join, contact Saman Maleki, PhD or John Ronald, PhD.

List of 2021-2022 publications by members.

Saman Maleki, PhD
Scientist - Cancer Research Laboratory
Program, Lawson Health Research Institute
Assistant Professor, Departments of Oncology,
and Pathology & Laboratory Medicine,
and Medical Biophysics, Schulich School
of Medicine & Dentistry, Western University.



John A. Ronald, PhD
Scientist, Robarts Research Institute - Imaging
Assistant Professor - Department of
Medical Biophysics, Western University

Cancer Immunology



Gregory Dekaban Glenn Bauman Robert Bartha
Rodney Dekoter Daniel Breadner Gregory Dekaban
Mansour Haeryfar David Edgell Paula Foster
James Koropatnick Scott Ernst Justin Hicks
Peeyush Lala Aaron Fenster Michael S. Kovacs
Shawn Shun-Cheng Li Ricardo Fernandes Ting-Yim Lee
Saman Maleki Paula Foster Len Luyt
Silvia Penuela

Gregory Gloor

John Ronald
Armen Parsyan Bogumil Karas Timothy Scholl
Christopher Pin James Koropatnick Jonathan Thiessen
Xiufen Zheng John Lenehan John Kelly
Weiping Min Ana Lohmann
Alma Omar Maria MacDonald
Ping Lu Saman Maleki
Xiao Zhou Zhen John McCormick
Jeremy Burton Jacques Raphael
Vanessa Dumeaux John Ronald
Munir A. Rahim Trevor Shepherd
Stephen Welch

Eric Winquist

John Kelly

Xiufen Zheng

Ping Lu

Xiao Zhou Zhen

Jeremy Burton

Shona Philip