Joseph S. Megyesi, MD, PhD, FRCSC


Professor of Neurosurgery, Western University
Office: London Health Sciences Centre, University Hospital B10-007
Phone: 519-663-3565
Secretary: Karen Hailstone



Bio Sketch

Dr. Megyesi received his MD from Western University in 1985. He completed a comprehensive surgical internship the same institution followed by a neurosurgical residency at the University of Alberta Hospitals in Edmonton. Following his training, Dr. Megyesi completed fellowships at Harvard University and the University of Alberta.

Dr. Megyesi joined the Department in 1998 and specializes in neuro-oncology. He is currently Assistant Professor in the Division of Neurosurgery at Western University. He is also Director of Research in the Division of Neurosurgery, coordinator of Neurosurgery Residency Seminar Series and Board Member of Brain Tumor Tissue Bank.


Dr. Megyesi's clinical research interests focus on angiogenesis in brain tumors. A tumor's ability to grow is linked to its ability to recruit a supply of new blood vessels. In order to do this, it sends out "signals" to already existing blood vessels to sprout new branches to feed it. This is the process of angiogenesis. His past studies have investigated angiogenic growth factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF).

Dr. Megyesi's research interests also include cerebral vasospasm in the brain. Cerebral vasospasm is delayed-onset, prolonged and pathological cerebral arterial narrowing following aneurysmal subarachnoid hemorrhage (SAH). His past work has looked at the treatment of this disorder using transluminal balloon angioplasty in an animal model.

Medical Interests

Cerebral Vasospasm, HIV Neuropathology, Technical Aspects of Intracranial Surgery, Angiogenisis and Invasion of Brain Tumours, Intratumoral Drug Delivery Systems for Malignant Brain Tumours, Molecular Signatures of Brain Tumours

Honours and Awards

  • 2017, Leader of Distinction Award, Brain Tumour Foundation of Canada
  • 2017, Ontario Volunteer Service Award, Ontario Mnistry of Citizenship and Immigration
  • 2011, Distinguished Reviewer of the Year Award, Canadian Journal of Neurological Sciences


PubMed Publications Listing


Lau JC, Kosteniuk SE, Bihari F, Megyesi JF. Functional Magnetic Resonance Imaging for Preoperative Planning in Brain Tumour Surgery. Can J Neurol Sci. 2017 Jan;44(1):59-68. doi: 10.1017/cjn.2016.306. PubMed PMID: 28004630.

Megyesi JF. Head Injury in the Elderly: Is Our Health Care System Ready for the Fall(s)? Can J Neurol Sci. 2014 Jul;41(4):407-8. PubMed PMID: 24878461.

Megyesi JF. Providing Information to our Patients: Published and Personal Perspectives. Can J Neurol Sci. 2014 Jan;41(1):3-4. PubMed PMID: 24384329.

Megyesi JF. A role for the surgeon-scientist? What does the "evidence" tell us? Can J Neurol Sci. 2013 Jul;40(4):450-2. PubMed PMID: 23786724.