Protein Biochemistry; Structural Biology
Members of the Macromolecular Structure and Dynamics Group study the role that specific proteins and protein systems play in certain diseases, with a focus on understanding protein function at the atomic and molecular levels. We frequently use biophysical techniques and conventional molecular biology to determine the 3-D structure, dynamics, and interactions of biomolecules. Methods include NMR spectroscopy, crystallography, proteomics, and mass spectrometry.
| Faculty Researcher | Research Area |
|---|---|
| * Eric Ball | Cytoskeletal proteins |
| James Choy | Intrinsically disordered proteins |
| Stanley Dunn | ATP synthase |
| Harvey Goldberg | Bone proteins |
| Robert Hudson | Bioorganic chemistry of nucleic acids and peptides |
| Murray Junop | DNA repair |
| Lars Konermann | Protein folding, dynamics, function; biocomputing |
| Gilles Lajoie | Mass spectrometry/proteomics: biomolecules |
| Shawn Li | Structure, function, connectivity of cellular proteins |
| Hong Ling | DNA damage response and regulation |
| David Litchfield | Signalling events in cell proliferation and survival |
| Patrick O'Donoghue | Synthesis of proteins containing atypical amino acids |
| David O'Gorman | Wound healing and Dupuytren's contracture |
| Gary Shaw | Calcium signalling proteins; protein degradation |
| Brian Shilton | Enzyme structure, mechanism, and biological function |
| Walter Siqueira | Salivary components and biomarkers |
| Ken Yeung | Microscale protein analysis |
