Recent Publications

picture of Dr. Shawn Li

2022

Jan 2022   Feb 2022   Mar 2022   Apr 2022   May 2022   June 2022

2021

Jan 2021   Feb 2021   Mar 2021   Apr 2021   May 2021   June 2021

July 2021   Aug 2021   Sept 2021   Oct 2021   Nov 2021   Dec 2021

Archives

 


June 2022

  1. Boffa MB, Koschinsky ML. Understanding the ins and outs of lipoprotein (a) metabolism. Curr Opin Lipidol. 2022 Jun 1;33(3):185-192.
  2. Dilliott AA, Zhang KK, Wang J, Abrahao A, Binns MA, Black SE, Borrie M, Dowlatshahi D, Finger E, Fischer CE, Frank A, Freedman M, Grimes D, Hassan A, Jog M, Kumar S, Lang AE, Mandzia J, Masellis M, Pasternak SH, Pollock BG, Rajji TK, Rogaeva E, Sahlas DJ, Saposnik G, Sato C, Seitz D, Shoesmith C, Steeves TDL, Swartz RH, Tan B, Tang-Wai DF, Tartaglia MC, Turnbull J, Zinman L; ONDRI Investigators, Hegele RA. Targeted copy number variant identification across the neurodegenerative disease spectrum. Mol Genet Genomic Med. 2022 Jun 3:e1986.
  3. Maitland MER, Lajoie GA, Shaw GS, Schild-Poulter C. Structural and Functional Insights into GID/CTLH E3 Ligase Complexes. Int J Mol Sci. 2022; 23(11):5863.

May 2022

  1. Boffa MB. Beyond fibrinolysis: The confounding role of Lp(a) in thrombosis. Atherosclerosis. 2022 May;349:72-81.
  2. Koschinsky ML, Boffa MB. Oxidized phospholipid modification of lipoprotein(a): Epidemiology, biochemistry and pathophysiology. Atherosclerosis. 2022 May;349:92-100.
  3. Berg MD, Zhu Y, Loll-Krippleber R, Luis BS, Genereaux J, Boone C, Villen J, Brown GW, Brandl CJ. Genetic background and mistranslation frequency determine the impact of mistranslating tRNASerUGG. G3 (Bethesda). 2022 May 19:jkac125.
  4. Hackam DG, Hegele RA. Lipid-Modifying Therapies and Stroke Prevention. Curr Neurol Neurosci Rep. 2022 May 13.
  5. Appleton CT, Hegele RA. Preventing cardiovascular events in patients with inflammatory arthritis: are we missing the mark? Can J Cardiol. 2022 May 20:S0828-282X(22)00322-1.
  6. Suri RS, Lee JY, Ban MR, Shrum B, Tutunea-Fatan E, Ismail OZ, Leckie S, McIntyre A, Xu Q, Lee SH, de Chickera S, Hegele RA, Gunaratnam L. Defective KIM-1 phagocytosis does not predispose to acute graft dysfunction after kidney transplantation in humans. Kidney Int. 2022 May 27:S0085-2538(22)00381-7.
  7. Siddika T, Heinemann IU, O'Donoghue P. Expanding codon size. Elife. 2022 May 11;11:e78869.
  8. Konermann L, Kim S. Grotthuss Molecular Dynamics Simulations for Modeling Proton Hopping in Electrosprayed Water Droplets. J Chem Theory Comput. 2022 May 11.
  9. Aliyari E, Konermann L. Formation of Gaseous Peptide Ions from Electrospray Droplets: Competition between the Ion Evaporation Mechanism and Charged Residue Mechanism. Anal Chem. 2022 May 19.
  10. Koschinsky ML, Kronenberg F. The long journey of lipoprotein(a) from cardiovascular curiosity to therapeutic target. Atherosclerosis. 2022 May;349:1-6.
  11. Fraser DD, Cepinskas G, Slessarev M, Martin CM, Daley M, Patel MA, Miller MR, Patterson EK, O'Gorman DB, Gill SE, Higgins I, John JPP, Melo C, Nini L, Wang X, Zeidler J, Cruz-Aguado JA. Critically Ill COVID-19 Patients Exhibit Anti-SARS-CoV-2 Serological Responses. Pathophysiology. 2021 May 17;28(2):212-223.
  12. Xu Y, Ward AD, Goldman D, Yin H, Arpino JM, Nong Z, Lee JJ, O'Neil C, Pickering JG. Arteriolar dysgenesis in ischemic, regenerating skeletal muscle revealed by automated micro-morphometry, computational modeling, and perfusion analysis. Am J Physiol Heart Circ Physiol. 2022 May 6.
  13. Saleh M, Colaiacovo S, Napier MP, Prasad AN, Rupar CA, Prasad C. Pitfalls in Genetic Testing for Consanguineous Pediatric Populations. Case Rep Genet. 2022 May 25;2022:9393042.

Apr 2022

  1. Clark JR, Gemin M, Youssef A, Marcovina SM, Prat A, Seidah NG, Hegele RA, Boffa MB, Koschinsky ML. Sortilin enhances secretion of apolipoprotein(a) through effects on apolipoprotein B secretion and promotes uptake of lipoprotein(a). J Lipid Res. 2022 Apr 22:100216.
  2. Rutledge BS, Choy WY, Duennwald ML. Folding or Holding? - Hsp70 and Hsp90 chaperoning of misfolded proteins in neurodegenerative disease. J Biol Chem. 2022 Apr 6:101905.
  3. Wilson CJ, Choy WY, Karttunen M. AlphaFold2: A Role for Disordered Protein/Region Prediction? Int J Mol Sci. 2022 Apr 21;23(9):4591.
  4. Dilliott AA, Andary CM, Stoltz M, Petropavlovskiy AA, Farhan SMK, Duennwald ML. DnaJC7 in Amyotrophic Lateral Sclerosis. Int J Mol Sci. 2022 Apr 7;23(8):4076.
  5. Slattery SS, Giguere DJ, Stuckless EE, Shrestha A, Briere LK, Galbraith A, Reaume S, Boyko X, Say HH, Browne TS, Frederick MI, Lant JT, Heinemann IU, O'Donoghue P, Dsouza L, Martin S, Howard P, Jedeszko C, Ali K, Styba G, Flatley M, Karas BJ, Gloor GB, Edgell DR. Phosphate-regulated expression of the SARS-CoV-2 receptor-binding domain in the diatom Phaeodactylum tricornutum for pandemic diagnostics. Sci Rep. 2022 Apr 29;12(1):7010.
  6. Jacob E, Hegele RA. Monogenic Versus Polygenic Forms of Hypercholesterolemia and Cardiovascular Risk: Are There Any Differences? Curr Atheroscler Rep. 2022 Apr 7.
  7. Blagojevic C, Heung T, Malecki S, Ying S, Cancelliere S, Hegele R, Bassett A. Hypertriglyceridemia in young adults with a 22q11.2 microdeletion. Eur J Endocrinol. 2022 Apr 1:EJE-21-1104.
  8. Lee SH, Pandya RK, Hussain JS, Lau RJ, Chambers EAB, Geng A, Jin BX, Zhou O, Wu T, Barr L, Junop M. Perceptions of using infographics for scientific communication on social media for COVID-19 topics: a survey study. J Vis Commun Med. 2022 Apr;45(2):39-47.
  9. Qin Y, Zheng Z, Chu B, Kong Q, Ke M, Voss C, Li SSC, Tian R. Generic Plug-and-Play Strategy for High-Throughput Analysis of PTM-Mediated Protein Complexes. Anal Chem. 2022 Apr 26.
  10. Luo J, Tugade T, Sun E, Pena Diaz AM, O'Gorman DB. Sustained AWT1 expression by Dupuytren's disease myofibroblasts promotes a proinflammatory milieu. J Cell Commun Signal. 2022 Apr 12.
  11. Matheson AM, Cunningham RSP, Bier E, Lu J, Dreihuys B, Pickering JG, Diamantouros P, Islam A, Nicholson JM, Parraga G, Blissett S. Hyperpolarized 129Xe Pulmonary MRI and Asymptomatic Atrial Septal Defect. Chest. 2022 Apr;161(4):e199-e202.
  12. Islam F, Leung KK, Walker MD, Al Massri S, Shilton BH. The Unusual Cosubstrate Specificity of NQO2: Conservation Throughout the Amniotes and Implications for Cellular Function. Front Pharmacol. 2022 Apr 20;13:838500.
  13. Sheikh-Mohamed S, Isho B, Chao GYC, Zuo M, Cohen C, Lustig Y, Nahass GR, Salomon-Shulman RE, Blacker G, Fazel-Zarandi M, Rathod B, Colwill K, Jamal A, Li Z, de Launay KQ, Takaoka A, Garnham-Takaoka J, Patel A, Fahim C, Paterson A, Li AX, Haq N, Barati S, Gilbert L, Green K, Mozafarihashjin M, Samaan P, Budylowski P, Siqueira WL, Mubareka S, Ostrowski M, Rini JM, Rojas OL, Weissman IL, Tal MC, McGeer A, Regev-Yochay G, Straus S, Gingras AC, Gommerman JL. Systemic and mucosal IgA responses are variably induced in response to SARS-CoV-2 mRNA vaccination and are associated with protection against subsequent infection. Mucosal Immunol. 2022 Apr 25:1–10.

Mar 2022

  1. Brumwell SL, Van Belois KD, Giguere DJ, Edgell DR, Karas BJ. Conjugation-Based Genome Engineering in Deinococcus radiodurans. ACS Synth Biol. 2022 Mar 7.
  2. Srichaikul K, Hegele RA, Jenkins DJA. Great Chinese Famine and the Effects on Cardiometabolic Health for Future Generations. Hypertension. 2022 Mar;79(3):532-535.
  3. Albatany M, Meakin S, Bartha R. Brain pH Measurement Using AACID CEST MRI Incorporating the 2 ppm Amine Resonance. Tomography. 2022 Mar 9;8(2):730-739.
  4. Nagree MS, Felizardo TC, Faber ML, Rybova J, Rupar CA, Foley SR, Fuller M, Fowler DH, Medin JA. Autologous, lentivirus-modified, T-rapa cell "micropharmacies" for lysosomal storage disorders. EMBO Mol Med. 2022 Mar 17:e14297.
  5. Rodrigues RPCB, Vidigal MTC, Vieira WA, Nascimento GG, Sabino-Silva R, Blumenberg C, Siqueira MF, Siqueira WL, Paranhos LR. Salivary changes in chronic kidney disease and in patients undergoing hemodialysis: a systematic review and meta-analysis. J Nephrol. 2022 Mar 2.
  6. Dunkerley KM, Rintala-Dempsey AC, Salzano G, Tadayon R, Hadi D, Barber KR, Walden H, Shaw GS. Distinct phosphorylation signals drive acceptor versus free ubiquitin chain targeting by Parkin. Biochem J. 2022 Mar 9:BCJ20210741.
  7. Lacoursiere RE, Hadi D, Shaw GS. Acetylation, Phosphorylation, Ubiquitination (Oh My!): Following Post-Translational Modifications on the Ubiquitin Road. Biomolecules. 2022 Mar 18;12(3):467.
  8. Silva PUJ, Oliveira MB, Vieira W, Cardoso SV, Blumenberg C, Franco A, Siqueira WL, Paranhos LR. Oral pigmentation as an adverse effect of chloroquine and hydroxychloroquine use: A scoping review. Medicine (Baltimore). 2022 Mar 18;101(11):e29044.
  9. Marin LM, Xiao Y, Cury JA, Siqueira WL. Engineered Salivary Peptides Reduce Enamel Demineralization Provoked by Cariogenic S. mutans Biofilm. Microorganisms. 2022 Mar 30;10(4):742.

Feb 2022

  1. Isaacson JR, Berg MD, Charles B, Jagiello J, Villén J, Brandl CJ, Moehring AJ. A Novel Mistranslating tRNA Model in Drosophila melanogaster has Diverse, Sexually Dimorphic Effects. G3 (Bethesda). 2022 Feb 10:jkac035.
  2. Habiby R, Bichet DG, Arthus MF, Connaughton D, Shril S, Mane S, Majmundar AJ, Hildebrandt F, Robertson GL. A Novel form of Familial Vasopressin Deficient Diabetes Insipidus Transmitted in an X-linked Recessive manner. J Clin Endocrinol Metab. 2022 Feb 9:dgac076.
  3. Buensuceso A, Fritz JL, Collins O, Valdés YR, Borrelli MJ, DiMattia GE, Shepherd TG. Loss of LKB1-NUAK1 signalling enhances NF-κB activity in a spheroid model of high-grade serous ovarian cancer. Sci Rep. 2022 Feb 22;12(1):3011.
  4. Daugherty A, Hegele RA, Lu HS, Mackman N, Rader DJ, Weber C. Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor. Arterioscler Thromb Vasc Biol. 2022 Feb 3:ATVBAHA122317426.
  5. Reijman MD, Schweizer A, Peterson ALH, Bruckert E, Stratz C, Defesche JC, Hegele RA, Wiegman A. Rationale and design of two trials assessing the efficacy, safety, and tolerability of inclisiran in adolescents with homozygous and heterozygous familial hypercholesterolaemia. Eur J Prev Cardiol. 2022 Feb 17:zwac025.
  6. Hegele RA. Apolipoprotein C-III inhibition to lower triglycerides: one ring to rule them all? Eur Heart J. 2022 Feb 17:ehab890.
  7. Berberich AJ, Hegele RA. Rapidly lowering triglyceride levels by plasma exchange in acute pancreatitis: What's the point? J Clin Apher. 2022 Feb 23.
  8. Blom DJ, Gaudet D, Hegele RA, Patel DS, Cegla J, Kolovou G, Marin LM. A Case Series Assessing the Effects of Lomitapide on Carotid Intima-Media Thickness in Adult Patients with Homozygous Familial Hypercholesterolaemia in a Real-World Setting. Adv Ther. 2022 Feb 23.
  9. Le R, Zhao L, Hegele RA. Forty year follow-up of three patients with complete absence of apolipoprotein B-containing lipoproteins. J Clin Lipidol. 2022 Feb 12:S1933-2874(22)00030-7.
  10. Frederick MI, Siddika T, Zhang P, Balasuriya N, Turk MA, O'Donoghue P, Heinemann IU. miRNA-Dependent Regulation of AKT1 Phosphorylation. Cells. 2022 Feb 26;11(5):821.
  11. Konermann L, Amster IJ, Smith JC, Verhaert PDEM. The 33rd International Tandem Mass Spectrometry Workshop, Lake Louise, Alberta, Canada. J Am Soc Mass Spectrom. 2022 Feb 14.
  12. Siu VM, Hutson JR, Rupar CA. Clinical Conundrum: Polyhydramnios as a marker for a fetal genetic syndrome in the Canadian Old Order Mennonite population. J Obstet Gynaecol Can. 2022 Feb 4:S1701-2163(22)00048-2.
  13. Onabote O, Hassan HM, Isovic M, Torchia J. The Role of Thymine DNA Glycosylase in Transcription, Active DNA Demethylation, and Cancer. Cancers (Basel). 2022 Feb 1;14(3):765.

Jan 2022

  1. Youssef A, Clark JR, Marcovina SM, Boffa MB, Koschinsky ML. ApoA and ApoB Interact Noncovalently Within Hepatocytes: Implications for Regulation of Lp(a) (Lipoprotein[a]) Levels by Modulation of ApoB Secretion. Arterioscler Thromb Vasc Biol. 2022 Jan 20:ATVBAHA121317335.
  2. Ngo V, Brickenden A, Liu H, Yeung C, Choy WY, Duennwald ML. A novel yeast model detects Nrf2 and Keap1 interactions with Hsp90. Dis Model Mech. 2022 Jan 28:dmm.049258.
  3. Salem A, Wilson CJ, Rutledge BS, Dilliott A, Farhan S, Choy WY, Duennwald ML. Matrin3: Disorder and ALS Pathogenesis. Front Mol Biosci. 2022 Jan 10;8:794646.
  4. Ngo V, Karunatilleke NC, Brickenden A, Choy WY, Duennwald ML. Oxidative Stress-Induced Misfolding and Inclusion Formation of Nrf2 and Keap1. Antioxidants (Basel). 2022 Jan 27;11(2):243.
  5. Wang C, Seltzsam S, Zheng B, Wu CW, Nicolas-Frank C, Yousef K, Au KS, Mann N, Pantel D, Schneider S, Schierbaum L, Kitzler TM, Connaughton DM, Mao Y, Dai R, Nakayama M, Kari JA, El Desoky S, Shalaby M, Eid LA, Awad HS, Tasic V, Mane SM, Lifton RP, Baum MA, Shril S, Estrada CR, Hildebrandt F. Whole exome sequencing identifies potential candidate genes for spina bifida derived from mouse models. Am J Med Genet A. 2022 Jan 18.
  6. Elhassan EAE, Murray SL, Connaughton DM, Kennedy C, Cormican S, Cowhig C, Stapleton C, Little MA, Kidd K, Bleyer AJ, Živná M, Kmoch S, Fennelly NK, Doyle B, Dorman A, Griffin MD, Casserly L, Harris PC, Hildebrandt F, Cavalleri GL, Benson KA, Conlon PJ. The utility of a genetic kidney disease clinic employing a broad range of genomic testing platforms: experience of the Irish Kidney Gene Project. J Nephrol. 2022 Jan 31.
  7. Tromp TR, Hartgers ML, Hovingh GK, Vallejo-Vaz AJ, Ray KK, Soran H, Freiberger T, Bertolini S, Harada-Shiba M, Blom DJ, Raal FJ, Cuchel M; Homozygous Familial Hypercholesterolaemia International Clinical Collaborators (includes Hegele RA). Worldwide experience of homozygous familial hypercholesterolaemia: retrospective cohort study. Lancet. 2022 Jan 28:S0140-6736(21)02001-8.
  8. Mozaffarian D, Maki KC, Bays HE, Aguilera F, Gould G, Hegele RA, Moriarty PM, Robinson JG, Shi P, Tur JF, Lapointe JF, Aziz S, Lemieux P; TRILOGY (Study of CaPre in Lowering Very High Triglycerides) investigators. Effectiveness of a Novel ω-3 Krill Oil Agent in Patients With Severe Hypertriglyceridemia: A Randomized Clinical Trial. JAMA Netw Open. 2022 Jan 4;5(1):e2141898.
  9. Yang JH, Friederich MW, Ellsworth KA, Frederick A, Foreman E, Malicki D, Dimmock D, Lenberg J, Prasad C, Yu AC, Rupar C, Hegele RA, Manickam K, Koboldt DC, Crist E, Choi SS, Farhan SMK, Harvey H, Sattar S, Karp N, Wong T, Haas R, Van Hove JLK, Wigby K. Expanding the phenotypic and molecular spectrum of NFS1-related disorders that cause functional deficiencies in mitochondrial and cytosolic iron-sulfur cluster containing enzymes. Hum Mutat. 2022 Jan 13.
  10. Rozik P, Szabla R, Lant JT, Kiri R, Wright DE, Junop M, O'Donoghue P. A novel fluorescent reporter sensitive to serine mis-incorporation. RNA Biol. 2022 Jan;19(1):221-233.
  11. Virani SS, Koschinsky ML, Maher L, Mehta A, Orringer CE, Santos RD, Shapiro MD, Saseen JJ. Global think tank on the clinical considerations and management of lipoprotein(a): The top questions and answers regarding what clinicians need to know. Prog Cardiovasc Dis. 2022 Jan 19:S0033-0620(22)00002-0.
  12. Gatie MI, Cooper TT, Khazaee R, Lajoie GA, Kelly GM. Lactate Enhances Mouse ES Cell Differentiation Toward XEN Cells In Vitro. Stem Cells. 2022 Jan 24:sxab022.
  13. Sanchez-Pupo RE, O'Donnell BL, Johnston D, Gyenis L, Litchfield DW, Penuela S. Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes. Mol Biol Cell. 2022 Jan 5:mbcE21080387.
  14. Rajaram A, Milej D, Suwalski M, Kebaya L, Kewin M, Yip L, de Ribaupierre S, Han V, Diop M, Bhattacharya S, St Lawrence K. Assessing cerebral blood flow, oxygenation and cytochrome c oxidase stability in preterm infants during the first 3 days after birth. Sci Rep. 2022 Jan 7;12(1):181.
  15. Marin LM, Xiao Y, Cury JA, Siqueira WL. Modulation of Streptococcus mutans Adherence to Hydroxyapatite by Engineered Salivary Peptides. Microorganisms. 2022 Jan 20;10(2):223.

Dec 2021

  1. Levy MA, McConkey H, Kerkhof J, Barat-Houari M, Bargiacchi S, Biamino E, Bralo MP, Cappuccio G, Ciolfi A, Clarke A, DuPont BR, Elting MW, Faivre L, Fee T, Fletcher RS, Cherik F, Foroutan A, Friez MJ, Gervasini C, Haghshenas S, Hilton BA, Jenkins Z, Kaur S, Lewis S, Louie RJ, Maitz S, Milani D, Morgan AT, Oegema R, Østergaard E, Pallares NR, Piccione M, Pizzi S, Plomp AS, Poulton C, Reilly J, Relator R, Rius R, Robertson S, Rooney K, Rousseau J, Santen GWE, Santos-Simarro F, Schijns J, Squeo GM, St John M, Thauvin-Robinet C, Traficante G, van der Sluijs PJ, Vergano SA, Vos N, Walden KK, Azmanov D, Balci T, Banka S, Gecz J, Henneman P, Lee JA, Mannens MMAM, Roscioli T, Siu V, Amor DJ, Baynam G, Bend EG, Boycott K, Brunetti-Pierri N, Campeau PM, Christodoulou J, Dyment D, Esber N, Fahrner JA, Fleming MD, Genevieve D, Kerrnohan KD, McNeill A, Menke LA, Merla G, Prontera P, Rockman-Greenberg C, Schwartz C, Skinner SA, Stevenson RE, Vitobello A, Tartaglia M, Alders M, Tedder ML, Sadikovic B. Novel diagnostic DNA methylation episignatures expand and refine the epigenetic landscapes of Mendelian disorders. HGG Adv. 2021 Dec 3;3(1):100075.
  2. Lüdtke TH, Kleppa MJ, Rivera-Reyes R, Connaughton D, Shril S, Hildebrandt F, Kispert A. Proteomic analysis identifies ZMYM2 as endogenous binding partner of TBX18 protein in 293 and A549 cells. Biochem J. 2021 Dec 22:BCJ20210642.
  3. Yao T, Rudak PT, Laumont CM, Michaud AR, Rashu R, Knier NN, Foster PJ, McWilliam HEG, Villadangos JA, Nelson BH, DiMattia GE, Shepherd TG, Haeryfar SMM. MAIT cells accumulate in ovarian cancer-elicited ascites where they retain their capacity to respond to MR1 ligands and cytokine cues. Cancer Immunol Immunother. 2021 Dec 2.
  4. Lazarte J, Hegele RA. Lamin A/C missense variants: from discovery to functional validation. NPJ Genom Med. 2021 Dec 3;6(1):102.
  5. Patni N, Hegele R, Garg A. Caveolar Dysfunction and Lipodystrophies. Eur J Endocrinol. 2021 Dec 1:EJE-21-1243.
  6. Hang S, Lazarte J, Hegele RA. Is Deprescription of Ezetimibe Safe in Familial Hypercholesterolemia Patients Taking Evolocumab? CJC Open. 2021 Dec 17;4(4):428-431.
  7. Morrow NM, Trzaskalski NA, Hanson AA, Fadzeyeva E, Telford DE, Chhoker SS, Sutherland BG, Edwards JY, Huff MW, Mulvihill EE. Nobiletin Prevents High-Fat Diet-Induced Dysregulation of Intestinal Lipid Metabolism and Attenuates Postprandial Lipemia. Arterioscler Thromb Vasc Biol. 2021 Dec 16:ATVBAHA121316896.
  8. Linossi EM, Li K, Veggiani G, Tan C, Dehkhoda F, Hockings C, Calleja DJ, Keating N, Feltham R, Brooks AJ, Li SS, Sidhu SS, Babon JJ, Kershaw NJ, Nicholson SE. Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands. Nat Commun. 2021 Dec 2;12(1):7032.
  9. Baksheeva VE, Roman AY, Villard C, Devred F, Byrne D, Yatoui D, Zalevsky AO, Vologzhannikova AA, Sokolov AS, Permyakov SE, Golovin AV, Shaw GS, Tsvetkov PO, Zernii EY. Mechanism of Zn2+ and Ca2+ Binding to Human S100A1. Biomolecules. 2021 Dec 3;11(12):1823.
  10. Yang J, Liao Q, Price M, Moriarity B, Wolf N, Felices M, Miller JS, Geller MA, Bendzick L, Hopps R, Starr TK, O'Connor CH, Tarullo S, Nelson AC, Turley E, Wang J, McCarthy JB. Chondroitin sulfate proteoglycan 4, a targetable oncoantigen that promotes ovarian cancer growth, invasion, cisplatin resistance and spheroid formation. Transl Oncol. 2021 Dec 20;16:101318.

Nov 2021

  1. Berg MD, Isaacson JR, Cozma E, Genereaux J, Lajoie P, Villén J, Brandl CJ. Regulating Expression of Mistranslating tRNAs by Readthrough RNA Polymerase II Transcription. ACS Synth Biol. 2021 Nov 2.
  2. Seltzsam S, Wang C, Zheng B, Mann N, Connaughton DM, Wu CW, Schneider S, Schierbaum L, Kause F, Kolvenbach CM, Nakayama M, Dai R, Ottlewski I, Schneider R, Deutsch K, Buerger F, Klämbt V, Mao Y, Onuchic-Whitford AC, Nicolas-Frank C, Yousef K, Pantel D, Lai EW, Salmanullah D, Majmundar AJ, Bauer SB, Rodig NM, Somers MJG, Traum AZ, Stein DR, Daga A, Baum MA, Daouk GH, Tasic V, Awad HS, Eid LA, El Desoky S, Shalaby M, Kari JA, Fathy HM, Soliman NA, Mane SM, Shril S, Ferguson MA, Hildebrandt F. Reverse phenotyping facilitates disease allele calling in exome sequencing of patients with CAKUT. Genet Med. 2021 Nov 16:S1098-3600(21)04137-X.
  3. Rosario FJ, Kelly AC, Gupta MB, Powell TL, Cox L, Jansson T. Mechanistic Target of Rapamycin Complex 2 Regulation of the Primary Human Trophoblast Cell Transcriptome. Front Cell Dev Biol. 2021 Nov 4;9:670980.
  4. Chora JR, Iacocca MA, Tichý L, Wand H, Kurtz CL, Zimmermann H, Leon A, Williams M, Humphries SE, Hooper AJ, Trinder M, Brunham LR, Costa Pereira A, Jannes CE, Chen M, Chonis J, Wang J, Kim S, Johnston T, Soucek P, Kramarek M, Leigh SE, Carrié A, Sijbrands EJ, Hegele RA, Freiberger T, Knowles JW, Bourbon M; ClinGen Familial Hypercholesterolemia Expert Panel. The Clinical Genome Resource (ClinGen) Familial Hypercholesterolemia Variant Curation Expert Panel consensus guidelines for LDLR variant classification. Genet Med. 2021 Nov 18:S1098-3600(21)04140-X.
  5. Jeraj N, Huang SS, Kennedy BA, Hegele RA. Treatment of Homozygous Familial Hypercholesterolemia With Evinacumab. CJC Open. 2021 Nov 29;4(3):347-349.
  6. Roy G, Couture P, Genest J, Ruel I, Baass A, Bergeron J, Brisson D, Brunham LR, Cermakova L, Gaudet D, Khoury E, Laflamme N, Kennedy BA, Hegele RA, Drouin-Chartier JP. Influence of the LDL-receptor genotype on statin response in heterozygous familial hypercholesterolemia: insights from the Canadian FH Registry. Can J Cardiol. 2021 Nov 10:S0828-282X(21)00822-9.
  7. Shamsudeen I, Hegele RA. Advances in the care of lipodystrophies. Curr Opin Endocrinol Diabetes Obes. 2021 Nov 24.
  8. Heimhalt M, Mukherjee P, Grainger RA, Szabla R, Brown C, Turner R, Junop MS, Berti PJ. An Inhibitor-in-Pieces Approach to DAHP Synthase Inhibition: Potent Enzyme and Bacterial Growth Inhibition. ACS Infect Dis. 2021 Nov 11.
  9. Ng YK, Tajoddin NN, Scrosati PM, Konermann L. Mechanism of Thermal Protein Aggregation: Experiments and Molecular Dynamics Simulations on the High-Temperature Behavior of Myoglobin. J Phys Chem B. 2021 Nov 22.
  10. Jain A, Huang R, Lee J, Jawa N, Lim YJ, Guron M, Abish S, Boutros PC, Brudno M, Carleton B, Cuvelier GDE, Gunaratnam L, Ho C, Adeli K, Kuruvilla S, Lajoie G, Liu G, Nathan PC, Rod Rassekh S, Rieder M, Waikar SS, Welch SA, Weir MA, Winquist E, Wishart DS, Zorzi AP, Blydt-Hansen T, Zappitelli M, Urquhart B. A Canadian Study of Cisplatin Metabolomics and Nephrotoxicity (ACCENT): A Clinical Research Protocol. Can J Kidney Health Dis. 2021 Nov 17;8:20543581211057708.
  11. Strum SW, Gyenis L, Litchfield DW. CSNK2 in cancer: pathophysiology and translational applications. Br J Cancer. 2021 Nov 12.
  12. Arpino JM, Yin H, Prescott EK, Staples SCR, Nong Z, Li F, Chevalier J, Balint B, O'Neil C, Mortuza R, Milkovich S, Lee JJ, Lorusso D, Sandig M, Hamilton DW, Holdsworth DW, Poepping TL, Ellis CG, Pickering JG. Low-flow intussusception and metastable VEGFR2 signaling launch angiogenesis in ischemic muscle. Sci Adv. 2021 Nov 26;7(48):eabg9509.
  13. Barootes HC, Prasad C, Rupar CA, Ashok D. An Unexpected Finding of Hepatosplenomegaly in a Pediatric Patient. Clin Pediatr (Phila). 2021 Nov 18:99228211059668.
  14. Marin LM, Cury JA, Siqueira WL. Validation of a cariogenic biofilm model by evaluating the effect of fluoride on enamel demineralization. J Microbiol Methods. 2021 Nov 27;192:106386.

Oct 2021

  1. Razzaq I, Berg MD, Jiang Y, Genereaux J, Uthayakumar D, Kim GH, Agyare-Tabbi M, Halder V, Brandl CJ, Lajoie P, Shapiro RS. The SAGA and NuA4 component Tra1 regulates Candida albicans drug resistance and pathogenesis. Genetics. 2021 Oct 2;219(2):iyab131.
  2. Lant JT, Kiri R, Duennwald ML, O'Donoghue P. Formation and persistence of polyglutamine aggregates in mistranslating cells. Nucleic Acids Res. 2021 Oct 28:gkab898.
  3. Grieves LA, Gloor GB, Bernards MA, MacDougall-Shackleton EA. Preen gland microbiota covary with major histocompatibility complex genotype in a songbird. R Soc Open Sci. 2021 Oct 6;8(10):210936.
  4. Perera SD, Muleta AD, Vlasschaert C, Hegele RA. Preprint servers in lipidology: current status and future role. Curr Opin Lipidol. 2021 Oct 25.
  5. Gill PK, Hegele RA. Familial combined hyperlipidemia is a polygenic trait. Curr Opin Lipidol. 2021 Oct 22.
  6. Berberich AJ, Hegele RA. A modern approach to dyslipidemia. Endocr Rev. 2021 Oct 22:bnab037.
  7. Haliyur R, Walker JT, Sanyoura M, Reihsmann CV, Shrestha S, Aramandla R, Poffenberger G, Ramirez AH, Redick SD, Babon JAB, Prasad N, Hegele RA, Kent SC, Harlan DM, Bottino R, Philipson LH, Brissova M, Powers AC. Integrated Analysis of the Pancreas and Islets Reveals Unexpected Findings in Human Male With Type 1 Diabetes. J Endocr Soc. 2021 Oct 29;5(12):bvab162.
  8. Scrosati PM, Yin V, Konermann L. Hydrogen/Deuterium Exchange Measurements May Provide an Incomplete View of Protein Dynamics: a Case Study on Cytochrome c. Anal Chem. 2021 Oct 13.
  9. Fasolo F, Jin H, Winski G, Chernogubova E, Pauli J, Winter H, Li DY, Glukha N, Bauer S, Metschl S, Wu Z, Koschinsky ML, Reilly M, Pelisek J, Kempf W, Eckstein HH, Soehnlein O, Matic L, Hedin U, Bäcklund A, Bergmark C, Paloschi V, Maegdefessel L. Long Non-coding RNA MIAT Controls Advanced Atherosclerotic Lesion Formation and Plaque Destabilization. Circulation. 2021 Oct 14.
  10. Reyes-Soffer G, Ginsberg HN, Berglund L, Duell PB, Heffron SP, Kamstrup PR, Lloyd-Jones DM, Marcovina SM, Yeang C, Koschinsky ML; American Heart Association Council on Arteriosclerosis, Thrombosis and Vascular Biology; Council on Cardiovascular Radiology and Intervention; and Council on Peripheral Vascular Disease. Lipoprotein(a): A Genetically Determined, Causal, and Prevalent Risk Factor for Atherosclerotic Cardiovascular Disease: A Scientific Statement From the American Heart Association. Arterioscler Thromb Vasc Biol. 2021 Oct 14:ATV0000000000000147.
  11. Ćulum NM, Cooper TT, Lajoie GA, Dayarathna T, Pasternak SH, Liu J, Fu Y, Postovit LM, Lagugné-Labarthet F. Characterization of ovarian cancer-derived extracellular vesicles by surface-enhanced Raman spectroscopy. Analyst. 2021 Oct 29.
  12. Petroff A, Pena Diaz A, Armstrong JJ, Gonga-Cavé BC, Hutnik C, O'Gorman DB. Understanding Inflammation-associated Ophthalmic Pathologies: A Novel 3D Co-culture Model of Monocyte-myofibroblast Immunomodulation. Ocul Immunol Inflamm. 2021 Oct 14:1-12.
  13. Ostheim P, Amundson SA, Badie C, Bazyka D, Evans AC, Ghandhi SA, Gomolka M, Riego ML, Rogan PK, Terbrueggen R, Woloschak GE, Zenhausern F, Kaatsch HL, Schüle S, Ullmann R, Port M, Abend M. Gene Expression for Biodosimetry and Effect Prediction Purposes: Promises, Pitfalls and Future Directions - Key Session ConRad 2021. International Journal of Radiation Biology. 2021 Oct.
  14. Hill SL, Rogan PK, Wang YX, Knoll JHM. Differentially accessible, single copy sequences form contiguous domains along metaphase chromosomes that are conserved among multiple tissues. Mol Cytogenet. 2021 Oct 20;14(1):49.
  15. Mucaki EJ, Shirley BC, Rogan PK. Improved radiation expression profiling in blood by sequential application of sensitive and specific gene signatures. Int J Rad Biol. 2021 Oct 26:1-62.
  16. Madathil S, Siqueira WL, Marin LM, Sanaulla FB, Faraj N, Quiñonez CR, McNally M, Glogauer M, Allison P. The incidence of COVID-19 among dentists practicing in the community in Canada: A prospective cohort study over a 6-month period. J Am Dent Assoc. 2021 Oct 25:S0002-8177(21)00658-9.
  17. Tolg C, Messam BJ, McCarthy JB, Nelson AC, Turley EA. Hyaluronan Functions in Wound Repair That Are Captured to Fuel Breast Cancer Progression. Biomolecules. 2021 Oct 20;11(11):1551.

Sept 2021

  1. Berg MD, Zhu Y, Ruiz BY, Loll-Krippleber R, Isaacson J, San Luis BJ, Genereaux J, Boone C, Villén J, Brown GW, Brandl CJ. The amino acid substitution affects cellular response to mistranslation. G3 (Bethesda). 2021 Sep 27;11(10):jkab218.
  2. Zheng B, Seltzsam S, Wang C, Schierbaum L, Schneider S, Wu CW, Dai R, Connaughton DM, Nakayama M, Mann N, Stajic N, Mane S, Bauer SB, Tasic V, Nam HJ, Shril S, Hildebrandt F. Whole exome sequencing identifies FOXL2, FOXA2 and FOXA3 as candidate genes for monogenic congenital anomalies of the kidneys and urinary tract. Nephrol Dial Transplant. 2021 Sep 2:gfab253. \
  3. Zheng B, Wang C, Seltzsam S, Schneider S, Schierbaum L, Wu W, Dai R, Connaughton DM, Nakayama M, Mann N, Bauer SB, Awad HS, Eid LA, Tasic V, Shril S, Hildebrandt F. A truncating NRIP1 variant in an Arabic family with congenital anomalies of the kidneys and urinary tract. Am J Med Genet A. 2021 Sep 15.
  4. Morey TM, Esmaeili MA, Duennwald ML, Rylett RJ. SPAAC Pulse-Chase: A Novel Click Chemistry-Based Method to Determine the Half-Life of Cellular Proteins. Front Cell Dev Biol. 2021 Sep 7;9:722560.
  5. Kakadia J, Biggar K, Jain B, Chen AW, Nygard K, Li C, Nathanielsz PW, Jansson T, Gupta MB. Mechanisms linking hypoxia to phosphorylation of insulin-like growth factor binding protein-1 in baboon fetuses with intrauterine growth restriction and in cell culture. FASEB J. 2021 Sep;35(9):e21788.
  6. Nandi P, Jang CE, Biggar K, Halari CD, Jansson T, Gupta MB. Mechanistic Target of Rapamycin Complex 1 Signaling Links Hypoxia to Increased IGFBP-1 Phosphorylation in Primary Human Decidualized Endometrial Stromal Cells. Biomolecules. 2021 Sep 18;11(9):1382.
  7. Ginsberg HN, Packard CJ, Chapman MJ, Borén J, Aguilar-Salinas CA, Averna M, Ference BA, Gaudet D, Hegele RA, Kersten S, Lewis GF, Lichtenstein AH, Moulin P, Nordestgaard BG, Remaley AT, Staels B, Stroes ESG, Taskinen MR, Tokgözoğlu LS, Tybjaerg-Hansen A, Stock JK, Catapano AL. Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society. Eur Heart J. 2021 Sep 2:ehab551. 
  8. Berberich AJ, Ouédraogo AM, Shariff SZ, Hegele RA, Clemens KK. Incidence, predictors and patterns of care of patients with very severe hypertriglyceridemia in Ontario, Canada: a population-based cohort study. Lipids Health Dis. 2021 Sep 3;20(1):98.
  9. (includes Hegele RA) EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Lancet. 2021 Sep 7:S0140-6736(21)01122-3.
  10. Shimizu-Albergine M, Basu D, Kanter JE, Kramer F, Kothari V, Barnhart S, Thornock C, Mullick AE, Clouet-Foraison N, Vaisar T, Heinecke JW, Hegele RA, Goldberg IJ, Bornfeldt KE. CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins. J Clin Invest. 2021 Sep 7:153285.
  11. Dilliott AA, Abdelhady A, Sunderland KM, Farhan SMK, Abrahao A, Binns MA, Black SE, Borrie M, Casaubon LK, Dowlatshahi D, Finger E, Fischer CE, Frank A, Freedman M, Grimes D, Hassan A, Jog M, Kumar S, Kwan D, Lang AE, Mandzia J, Masellis M, McIntyre AD, Pasternak SH, Pollock BG, Rajji TK, Rogaeva E, Sahlas DJ, Saposnik G, Sato C, Seitz D, Shoesmith C, Steeves TDL, Swartz RH, Tan B, Tang-Wai DF, Tartaglia MC, Turnbull J, Zinman L; ONDRI Investigators, Hegele RA. Contribution of rare variant associations to neurodegenerative disease presentation. NPJ Genom Med. 2021 Sep 28;6(1):80.
  12. Heidari A, Hermann M, Hudson RHE. A simple fluorescent assay for the detection of peptide nucleic acid-directed double strand duplex invasion. Biopolymers. 2021 Sep 16:e23475.
  13. Aliyari E, Konermann L. Atomistic Insights into the Formation of Nonspecific Protein Complexes during Electrospray Ionization. Anal Chem. 2021 Sep 8.
  14. Maitland MER, Kuljanin M, Wang X, Lajoie GA, Schild-Poulter C. Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex-dependent regulation of glycolysis. FASEB J. 2021 Sep;35(9):e21825. 
  15. Qin L, Cao X, Kaneko T, Voss C, Liu X, Wang G, Li SS. Dynamic interplay of two molecular switches enabled by the MEK1/2-ERK1/2 and IL-6-STAT3 signaling axes controls epithelial cell migration in response to growth factors. J Biol Chem. 2021 Sep 1:101161. 
  16. Roffey SE, Litchfield DW. CK2 Regulation: Perspectives in 2021. Biomedicines. 2021; 9(10):1361.
  17. Wright DE, Panaseiko N, O'Donoghue P. Acetylated Thioredoxin Reductase 1 Resists Oxidative Inactivation. Front Chem. 2021 Sep 15;9:747236.
  18. Messam BJ, Tolg C, McCarthy JB, Nelson AC, Turley EA. RHAMM Is a Multifunctional Protein That Regulates Cancer Progression. Int J Mol Sci. 2021 Sep 24;22(19):10313.

Aug 2021

  1. Koschinsky ML, Boffa MB. Genetics to the Rescue: Sophisticated Approaches Provide Critical Insights Into the Determination of Lp(a) Levels. J Am Coll Cardiol. 2021 Aug 3;78(5):450-452.
  2. Kolvenbach CM, van der Ven AT, Kause F, Shril S, Scala M, Connaughton DM, Mann N, Nakayama M, Dai R, Kitzler TM, Schneider R, Schierbaum L, Schneider S, Accogli A, Torella A, Piatelli G, Nigro V, Capra V, Hoppe B, Märzheuser S, Schmiedeke E, Rehm HL, Mane S, Lifton RP, Dworschak GC, Hilger AC, Reutter H, Hildebrandt F. Exome survey of individuals affected by VATER/VACTERL with renal phenotypes identifies phenocopies and novel candidate genes. Am J Med Genet A. 2021 Aug 2. 
  3. Brunham LR, Hegele RA. What Is the Prevalence of Familial Hypercholesterolemia? Arterioscler Thromb Vasc Biol. 2021 Aug 26:ATVBAHA121316862.
  4. Paquette M, Bernard S, Cariou B, Hegele RA, Genest J, Trinder M, Brunham LR, Béliard S, Baass A. Familial Hypercholesterolemia-Risk-Score: A New Score Predicting Cardiovascular Events and Cardiovascular Mortality in Familial Hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2021 Aug 26:ATVBAHA121316106.
  5. Mitteaux J, Lejault P, Wojciechowski F, Joubert A, Boudon J, Desbois N, Gros CP, Hudson RHE, Boulé JB, Granzhan A, Monchaud D. Identifying G-Quadruplex-DNA-Disrupting Small Molecules. J Am Chem Soc. 2021 Aug 4.
  6. Karas BJ, Ross L, Novero M, Amyot L, Shrestha A, Inada S, Nakano M, Sakai T, Bonetta D, Sato S, Murray JD, Bonfante P, Szczyglowski K. Intragenic complementation at the Lotus japonicus CELLULOSE SYNTHASE-LIKE D1 locus rescues root hair defects. Plant Physiol. 2021 Aug 3;186(4):2037-2050.
  7. Miquel J, Huang TB, Athwal GS, Faber KJ, O'Gorman DB. Vancomycin is Effective in Preventing C. acnes Growth in a Shoulder Arthroplasty Mimetic. J Shoulder Elbow Surg. 2021 Aug 2:S1058-2746(21)00573-5.
  8. Yan X, Kumar K, Miclette Lamarche R, Youssef H, Shaw GS, Marcotte I, DeWolf CE, Warschawski DE, Boisselier E. Interactions between the Cell Membrane Repair Protein S100A10 and Phospholipid Monolayers and Bilayers. Langmuir. 2021 Aug 2. 
  9. Moussa DG, Siqueira WL. Bioinspired caries preventive strategy via customizable pellicles of saliva-derived protein/peptide constructs. Sci Rep. 2021 Aug 20;11(1):17007.

July 2021

  1. Maani N, Panabaker K, McCuaig JM, Buckley K, Semotiuk K, Farncombe KM, Ainsworth P, Panchal S, Sadikovic B, Armel SR, Lin H, Kim RH. Incidental findings from cancer next generation sequencing panels. NPJ Genom Med. 2021 Jul 19;6(1):63.
  2. Bhai P, Levy MA, Rooney K, Carere DA, Reilly J, Kerkhof J, Volodarsky M, Stuart A, Kadour M, Panabaker K, Schenkel LC, Lin H, Ainsworth P, Sadikovic B. Analysis of Sequence and Copy Number Variants in Canadian Patient Cohort With Familial Cancer Syndromes Using a Unique Next Generation Sequencing Based Approach. Front Genet. 2021 Jul 13;12:698595.
  3. Bourgeois R, Bourgault J, Despres AA, Perrot N, Guertin J, Girard A, Mitchell PL, Gotti C, Bourassa S, Scipione CA, Gaudreault N, Boffa MB, Koschinsky ML, Pibarot P, Droit A, Thériault S, Mathieu P, Bossé Y, Arsenault BJ. Lipoprotein Proteomics and Aortic Valve Transcriptomics Identify Biological Pathways Linking Lipoprotein(a) Levels to Aortic Stenosis. Metabolites. 2021 Jul 16;11(7):459. 
  4. Karunatilleke NC, Fast CS, Ngo V, Brickenden A, Duennwald ML, Konermann L, Choy WY. Nrf2, the Major Regulator of the Cellular Oxidative Stress Response, is Partially Disordered. Int J Mol Sci. 2021 Jul 11;22(14):7434.
  5. Chen AW, Biggar K, Nygard K, Singal S, Zhao T, Li C, Nathanielsz PW, Jansson T, Gupta MB. IGFBP-1 hyperphosphorylation in response to nutrient deprivation is mediated by activation of protein kinase Cα (PKCα). Mol Cell Endocrinol. 2021 Jul 24;536:111400.
  6. Lazarte J, Hegele RA. Volanesorsen for treatment of familial chylomicronemia syndrome. Expert Rev Cardiovasc Ther. 2021 Jul 15. 
  7. Lazarte J, Wang J, McIntyre AD, Hegele RA. Prevalence of severe hypertriglyceridemia and pancreatitis in familial partial lipodystrophy type 2. J Clin Lipidol. 2021 Jul 19:S1933-2874(21)00118-5.
  8. Chung CZ, Balasuriya N, Siddika T, Frederick MI, Heinemann IU. Gld2 activity and RNA specificity is dynamically regulated by phosphorylation and interaction with QKI-7. RNA Biol. 2021 Jul 21:1-12.
  9. O'Donoghue P, Heinemann IU, Fan C. Editorial: Synthetic Nucleic Acids for Expanding Genetic Codes and Probing Living Cells. Front Bioeng Biotechnol. 2021 Jul 2;9:720534.
    St-Denis NA, Derksen DR, Litchfield DW. Correction for St-Denis et al., "Evidence for Regulation of Mitotic Progression through Temporal Phosphorylation and Dephosphorylation of CK2α". Mol Cell Biol. 2021 Jul 23;41(8):e0027421.
  10. Gonga-Cavé BC, Pena Diaz AM, O'Gorman DB. Biomimetic analyses of interactions between macrophages and palmar fascia myofibroblasts derived from Dupuytren's disease reveal distinct inflammatory cytokine responses. Wound Repair Regen. 2021 Jul;29(4):627-636. 
  11. Huang TB, Pena Diaz AM, Faber KJ, Athwal GS, Woolman M, Nygard K, Keenliside L, O'Gorman DB. Development of a 3D Bioartificial Shoulder Joint Implant Mimetic of Periprosthetic Joint Infection. Tissue Eng Part A. 2021 Jul 26.
  12. Siqueira WL, Canales MP, Crosara KTB, Marin LM, Xiao Y. Proteome difference among the salivary proteins adsorbed onto metallic orthodontic brackets and hydroxyapatite discs. PLoS One. 2021 Jul 28;16(7):e0254909.
  13. Moraes G, Zambom C, Siqueira WL. Nanoparticles in Dentistry: A Comprehensive Review. Pharmaceuticals (Basel). 2021 Jul 30;14(8):752.

June 2021

  1. Aref-Eshghi E, Kerkhof J, Pedro VP, France GD, Barat-Houari M, Ruiz-Pallares N, Andrau JC, Lacombe D, Van-Gils J, Fergelot P, Dubourg C, Cormier-Daire V, Rondeau S, Lecoquierre F, Saugier-Veber P, Nicolas G, Lesca G, Chatron N, Sanlaville D, Vitobello A, Faivre L, Thauvin-Robinet C, Laumonnier F, Raynaud M, Alders M, Mannens M, Henneman P, Hennekam RC, Velasco G, Francastel C, Ulveling D, Ciolfi A, Pizzi S, Tartaglia M, Heide S, Héron D, Mignot C, Keren B, Whalen S, Afenjar A, Bienvenu T, Campeau PM, Rousseau J, Levy MA, Brick L, Kozenko M, Balci TB, Siu VM, Stuart A, Kadour M, Masters J, Takano K, Kleefstra T, de Leeuw N, Field M, Shaw M, Gecz J, Ainsworth PJ, Lin H, Rodenhiser DI, Friez MJ, Tedder M, Lee JA, DuPont BR, Stevenson RE, Skinner SA, Schwartz CE, Genevieve D, Sadikovic B. Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders. Am J Hum Genet. 2021 Jun 3;108(6):1161-1163.
  2. Voss C, Esmail S, Liu X, Knauer MJ, Ackloo S, Kaneko T, Lowes LE, Stogios PJ, Seitova A, Hutchinson A, Yusifov F, Skarina T, Evdokimova E, Loppnau P, Ghiabi P, Hajian T, Zhong S, Abdoh H, Hedley BD, Bhayana V, Martin CM, Slessarev M, Chin-Yee B, Fraser DD, Chin-Yee I, Li SS. Epitope-specific antibody responses differentiate COVID-19 outcome and variants of concern. JCI Insight. 2021 Jun 3:148855.
  3. Ikeda KM, House AA, Connaughton DM, Pautler SE, Siu VM, Jones ML. Potential Pitfalls in Pre-implantation Genetic Diagnosis in a Patient with Tuberous Sclerosis and Isolated Mosaicism for a TSC2 Variant in Renal Tissue. Mol Syndromol. 2021 Jun;12(3):154-158. 
  4. Lazarte J, Kanagalingam T, Hegele RA. Lipid effects of sodium-glucose cotransporter 2 inhibitors. Curr Opin Lipidol. 2021 Jun 1;32(3):183-190.
  5. Berberich AJ, Hegele RA. Lipid effects of glucagon-like peptide 1 receptor analogs. Curr Opin Lipidol. 2021 Jun 1;32(3):191-199.
  6. Awan ZA, Rashidi OM, Al-Shehri BA, Jamil K, Elango R, Al-Aama JY, Hegele RA, Banaganapalli B, Shaik NA. Saudi Familial Hypercholesterolemia Patients With Rare LDLR Stop Gain Variant Showed Variable Clinical Phenotype and Resistance to Multiple Drug Regimen. Front Med (Lausanne). 2021 Jun 25;8:694668. 
  7. Yin H, Arpino JM, Lee JJ, Pickering JG. Regenerated Microvascular Networks in Ischemic Skeletal Muscle. Front Physiol. 2021 Jun 11;12:662073. 
  8. Lambrughi M, Maiani E, Aykac Fas B, Shaw GS, Kragelund BB, Lindorff-Larsen K, Teilum K, Invernizzi G, Papaleo E. Ubiquitin Interacting Motifs: Duality Between Structured and Disordered Motifs. Front Mol Biosci. 2021 Jun 28;8:676235. 
  9. Saeed SG, Bain JL, Khoo E, Siqueira WL, van der Hoeven R. Should attendance for preclinical simulation and clinical education be mandatory? J Dent Educ. 2021 Jun 24. 
  10. Tolg C, Cowman M, Turley EA. Hyaluronan Isolation from Mouse Mammary Gland. Bio Protoc. 2018 Jun 5;8(11):e2865.

May 2021

  1. Chang CA, Perrier R, Kurek KC, Estrada-Veras J, Lehman A, Yip S, Hendson G, Diamond C, Pinchot JW, Tran JM, Arkin LM, Drolet BA, Napier MP, O'Neill SA, Balci TB, Keppler-Noreuil KM. Novel findings and expansion of phenotype in a mosaic RASopathy caused by somatic KRAS variants. Am J Med Genet A. 2021 May 30.
  2. Esmail S, Knauer MJ, Abdoh H, Voss C, Chin-Yee B, Stogios P, Seitova A, Hutchinson A, Yusifov F, Skarina T, Evdokimova E,  Ackloo S, Lowes L, Hedley BD, Bhayana V, Chin-Yee I, Li SSC. Rapid and accurate agglutination-based testing for SARS-CoV-2 antibodies. Cell Rep Met. 2021 May 12.
  3. Wilson CJ, Chang M, Karttunen M, Choy WY. KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability. Int J Mol Sci. 2021 May 20;22(10):5408.
  4. Grieves LA, Gloor GB, Kelly TR, Bernards MA, MacDougall-Shackleton EA. Preen gland microbiota of songbirds differ across populations but not sexes. J Anim Ecol. 2021 May 18.
  5. Vlasschaert C, McIntyre AD, Thomson LA, Kennedy BA, Ratko S, Prasad C, Hegele RA. Abetalipoproteinemia Due to a Novel Splicing Variant in MTTP in 3 Siblings. J Investig Med High Impact Case Rep. 2021 Jan-Dec;9:23247096211022484.
  6. Parajuli RP, Goodrich JM, Chan HM, Lemire M, Ayotte P, Hegele RA, Basu N. Variation in biomarker levels of metals, persistent organic pollutants, and omega-3 fatty acids in association with genetic polymorphisms among Inuit in Nunavik, Canada. Environ Res. 2021 May 29;200:111393.
  7. Dron JS, Hegele RA. Discussing polygenic risk with lipid clinic patients. Curr Opin Lipidol. 2021 May 28.
  8. Gill PK, Dron JS, Hegele RA. Genetics of hypertriglyceridemia and atherosclerosis. Curr Opin Cardiol. 2021 May 1;36(3):264-271.
  9. Burnett JR, Hooper AJ, Hegele RA. APOB-Related Familial Hypobetalipoproteinemia. 2021 May 13. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Mirzaa G, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2021.
  10. Leclerc CJ, Cooper TT, Bell GI, Lajoie GA, Flynn LE, Hess DA. Decellularized adipose tissue scaffolds guide hematopoietic differentiation and stimulate vascular regeneration in a hindlimb ischemia model. Biomaterials. 2021 May 8;274:120867.
  11. Ha SD, Lewin N, Li SSC, Kim SO. HDAC8 Activates AKT through Upregulating PLCB1 and Suppressing DESC1 Expression in MEK1/2 Inhibition-Resistant Cells. Cells. 2021 May 4;10(5):1101.
  12. Postma JK, Altamirano-Diaz L, Rupar CA, Siu VM. Symptomatic mosaicism for a novel FBN1 splice site variant in a parent causing inherited neonatal Marfan syndrome. Am J Med Genet A. 2021 May 14.
  13. Caixeta DC, Oliveira SW, Cardoso-Sousa L, Cunha TM, Goulart LR, Martins MM, Marin LM, Jardim ACG, Siqueira WL, Sabino-Silva R. One-Year Update on Salivary Diagnostic of COVID-19. Front Public Health. 2021 May 21;9:589564.

Apr 2021

  1. Chowdhury F, Wang L, Al-Raqad M, Amor DJ, Baxová A, Bendová Š, Biamino E, Brusco A, Caluseriu O, Cox NJ, Froukh T, Gunay-Aygun M, Hančárová M, Haynes D, Heide S, Hoganson G, Kaname T, Keren B, Kosaki K, Kubota K, Lemons JM, Magriña MA, Mark PR, McDonald MT, Montgomery S, Morley GM, Ohnishi H, Okamoto N, Rodriguez-Buritica D, Rump P, Sedláček Z, Schatz K, Streff H, Uehara T, Walia JS, Wheeler PG, Wiesener A, Zweier C, Kawakami K, Wentzensen IM, Lalani SR, Siu VM, Bi W, Balci TB. Haploinsufficiency of PRR12 causes a spectrum of neurodevelopmental, eye, and multisystem abnormalities. Genet Med. 2021 Apr 6.
  2. Chang M, Wilson CJ, Karunatilleke NC, Moselhy MH, Karttunen M, Choy WY. Exploring the Conformational Landscape of the Neh4 and Neh5 Domains of Nrf2 Using Two Different Force Fields and Circular Dichroism. J Chem Theory Comput. 2021 Apr 16.
  3. Renaud JB, DesRochers N, Hoogstra S, Garnham CP, Sumarah MW. Structure Activity Relationship for Fumonisin Phytotoxicity. Chem Res Toxicol. 2021 Apr 23.
  4. Walker RH, Hegele RA, Danek A. Comment on "A New Allelic Variant in the PANK2 Gene in a Patient with Incomplete HARP Syndrome". J Mov Disord. 2021 Apr 6.
  5. Narayanan DL, Tuteja M, McIntyre AD, Hegele RA, Calmels N, Obringer C, Laugel V, Mandal K, Phadke SR. Clinical and Mutation Spectra of Cockayne Syndrome in India. Neurol India. 2021 Mar-Apr;69(2):362-366.
  6. Dilliott AA, Sunderland KM, McLaughlin PM, Roberts AC, Evans EC, Abrahao A, Binns MA, Black SE, Borrie M, Casaubon LK, Dowlatshahi D, Finger E, Fischer CE, Frank A, Freedman M, Grimes D, Hassan A, Jog M, Kumar S, Kwan D, Lang AE, Mandzia J, Marras C, Masellis M, McIntyre AD, Pasternak S, Pollock BG, Rajji TK, Robinson JF, Rogaeva E, Sahlas DJ, Saposnik G, Sato C, Seitz D, Shoesmith C, Steeves T, Strother SC, Swartz RH, Tan B, Tang-Wai D, Tartaglia MC, Troyer AK, Turnbull J, Zinman L; ONDRI Investigators, Hegele RA. Association of apolipoprotein E variation with cognitive impairment across multiple neurodegenerative diagnoses. Neurobiol Aging. 2021 Apr 24:S0197-4580(21)00126-3.
  7. Konermann L, Aliyari E, Lee JH. Mobile Protons Limit the Stability of Salt Bridges in the Gas Phase: Implications for the Structures of Electrosprayed Protein Ions. J Phys Chem B. 2021 Apr 13.
  8. Abbasi S, Parmar G, Kelly RD, Balasuriya N, Schild-Poulter C. The Ku complex: recent advances and emerging roles outside of non-homologous end-joining. Cell Mol Life Sci. 2021 Apr 15.
  9. Lacoursiere RE, Shaw GS. Acetylated Ubiquitin Modulates the Catalytic Activity of the E1 Enzyme Uba1. Biochemistry. 2021 Apr 13.
  10. Zhu Y, Marin LM, Xiao Y, Gillies ER, Siqueira WL. pH-Sensitive Chitosan Nanoparticles for Salivary Protein Delivery. Nanomaterials (Basel). 2021 Apr 17;11(4):1028.

Mar 2021

  1. Glodowski M, Christen S, Saxon DR, Hegele RA, Eckel RH. Novel PPARG mutation in multiple family members with chylomicronemia. J Clin Lipidol. 2021 Mar 26:S1933-2874(21)00057-X.
  2. Gouni-Berthold I, Alexander VJ, Yang Q, Hurh E, Steinhagen-Thiessen E, Moriarty PM, Hughes SG, Gaudet D, Hegele RA, O'Dea LSL, Stroes ESG, Tsimikas S, Witztum JL; COMPASS study group. Efficacy and safety of volanesorsen in patients with multifactorial chylomicronaemia (COMPASS): a multicentre, double-blind, randomised, placebo-controlled, phase 3 trial. Lancet Diabetes Endocrinol. 2021 Mar 30:S2213-8587(21)00046-2.
  3. Volkening K, Farhan SMK, Kao J, Leystra-Lantz C, Ang LC, McIntyre A, Wang J, Hegele RA, Strong MJ. Evidence of synergism among three genetic variants in a patient with LMNA-related lipodystrophy and amyotrophic lateral sclerosis leading to a remarkable nuclear phenotype. Mol Cell Biochem. 2021 Mar 4.
  4. Wand H, Lambert SA, Tamburro C, Iacocca MA, O'Sullivan JW, Sillari C, Kullo IJ, Rowley R, Dron JS, Brockman D, Venner E, McCarthy MI, Antoniou AC, Easton DF, Hegele RA, Khera AV, Chatterjee N, Kooperberg C, Edwards K, Vlessis K, Kinnear K, Danesh JN, Parkinson H, Ramos EM, Roberts MC, Ormond KE, Khoury MJ, Janssens ACJW, Goddard KAB, Kraft P, MacArthur JAL, Inouye M, Wojcik GL. Improving reporting standards for polygenic scores in risk prediction studies. Nature. 2021 Mar;591(7849):211-219.
  5. Lazarte J, Laksman ZW, Wang J, Robinson JF, Dron JS, Leach E, Liew J, McIntyre AD, Skanes AC, Gula LJ, Leong-Sit P, Cao H, Trost B, Scherer SW, Hegele RA, Roberts JD. Enrichment of loss-of-function and copy number variants in ventricular cardiomyopathy genes in 'lone' atrial fibrillation. Europace. 2021 Mar 3:euaa421.
  6. Pearson GJ, Thanassoulis G, Anderson TJ, Barry AR, Couture P, Dayan N, Francis GA, Genest J, Grégoire J, Grover SA, Gupta M, Hegele RA, Lau D, Leiter LA, Leung AA, Lonn E, Mancini GBJ, Manjoo P, McPherson R, Ngui D, Piché ME, Poirier P, Sievenpiper J, Stone J, Ward R, Wray W. 2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult. Can J Cardiol. 2021 Mar 26:S0828-282X(21)00165-3.
  7. Buzon B, Grainger RA, Rzadki C, Huang SYM, Junop M. Identification of Bioactive SNM1A Inhibitors. ACS Omega. 2021 Mar 31;6(14):9352-9361.
  8. Pelletier JF, Sun L, Wise KS, Assad-Garcia N, Karas BJ, Deerinck TJ, Ellisman MH, Mershin A, Gershenfeld N, Chuang RY, Glass JI, Strychalski EA. Genetic requirements for cell division in a genomically minimal cell. Cell. 2021 Mar 26:S0092-8674(21)00293-2.
  9. Dieters-Castator D, Dantonio PM, Piaseczny M, Zhang G, Liu J, Kuljanin M, Sherman S, Jewer M, Quesnel K, Kang EY, Köbel M, Siegers GM, Leask A, Hess D, Lajoie G, Postovit LM. Embryonic protein NODAL regulates the breast tumor microenvironment by reprogramming cancer-derived secretomes. Neoplasia. 2021 Mar 27;23(4):375-390.
  10. Liu AD, Zhou J, Bi XY, Hou GQ, Li SS, Chen Q, Xu H, Cao X. Aptamer-SH2 superbinder-based targeted therapy for pancreatic ductal adenocarcinoma. Clin Transl Med. 2021 Mar;11(3):e337.
  11. Fraser DD, Cepinskas G, Slessarev M, Martin CM, Daley M, Patel MA, Miller MR, Patterson EK, O'Gorman DB, Gill SE, Oehler S, Miholits M, Webb B. Detection and Profiling of Human Coronavirus Immunoglobulins in Critically Ill Coronavirus Disease 2019 Patients. Crit Care Explor. 2021 Mar 12;3(3):e0369.
  12. Rogan PK, Mucaki EJ, Shirley BC, Li Y, Wilkins RC, Norton F, Sevriukova O, Pham N-D, Waller E, Knoll JHM. Automated Cytogenetic Biodosimetry at Population-Scale. Radiation. 2021; 1(2):79-94.
  13. Abbasi S, Schild-Poulter C. Identification of Ku70 Domain-Specific Interactors Using BioID2. Cells. 2021 Mar 14;10(3):646.
  14. Tokarew JM, El-Kodsi DN, Lengacher NA, Fehr TK, Nguyen AP, Shutinoski B, O'Nuallain B, Jin M, Khan JM, Ng ACH, Li J, Jiang Q, Zhang M, Wang L, Sengupta R, Barber KR, Tran A, Im DS, Callaghan S, Park DS, Zandee S, Dong X, Scherzer CR, Prat A, Tsai EC, Takanashi M, Hattori N, Chan JA, Zecca L, West AB, Holmgren A, Puente L, Shaw GS, Toth G, Woulfe JM, Taylor P, Tomlinson JJ, Schlossmacher MG. Age-associated insolubility of parkin in human midbrain is linked to redox balance and sequestration of reactive dopamine metabolites. Acta Neuropathol. 2021 Mar 10.
  15. Gundogdu M, Tadayon R, Salzano G, Shaw GS, Walden H. A mechanistic review of Parkin activation. Biochim Biophys Acta Gen Subj. 2021 Mar 20;1865(6):129894.
  16. Pellissari CVG, Jorge JH, Marin LM, Sabino-Silva R, Siqueira WL. Statherin-derived peptides as antifungal strategy against Candida albicans. Arch Oral Biol. 2021 Mar 16;125:105106.
  17. Chen C, Laviolette SR, Whitehead SN, Renaud JB, Yeung KK. Imaging of Neurotransmitters and Small Molecules in Brain Tissues Using Laser Desorption/Ionization Mass Spectrometry Assisted with Zinc Oxide Nanoparticles. J Am Soc Mass Spectrom. 2021 Mar 30.

Feb 2021

  1. Sadikovic B, Levi MA, Kerkhof J, Aref-Eshghi E, Schenkel L, Stuart A, McConkey H, Henneman P, Venema A, Schwartz CE, Stevenson RE, Skinner SA, DuPont BR, Fletcher RS, Balci TB, Siu VM, Granadillo JL, Masters J, Kadour M, Friez MJ, van Haelst MM, Mannens MMAM, Louie RJ, Lee JA, Tedder ML, Alders M. Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders. Genet Med. 2021 Feb 5.
  2. Sadikovic B, Levy MA, Kerkhof J, Aref-Eshghi E, Schenkel L, Stuart A, McConkey H, Henneman P, Venema A, Schwartz CE, Stevenson RE, Skinner SA, DuPont BR, Fletcher RS, Balci TB, Siu VM, Granadillo JL, Masters J, Kadour M, Friez MJ, van Haelst MM, Mannens MMAM, Louie RJ, Lee JA, Tedder ML, Alders M. Correction: Clinical epigenomics: genome-wide DNA methylation analysis for the diagnosis of Mendelian disorders. Genet Med. 2021 Feb 26.
  3. Marcovina SM, Clouet-Foraison N, Koschinsky ML, Lowenthal MS, Orquillas A, Boffa MB, Hoofnagle AN, Vaisar T. Development of an LC-MS/MS Proposed Candidate Reference Method for the Standardization of Analytical Methods to Measure Lipoprotein(a). Clin Chem. 2021 Feb 1:hvaa324.
  4. Sun B, Yao J, Ni M, Wei J, Zhong X, Guo W, Zhang L, Wang R, Belke D, Chen YX, Lieve KVV, Broendberg AK, Roston TM, Blankoff I, Kammeraad JA, von Alvensleben JC, Lazarte J, Vallmitjana A, Bohne LJ, Rose RA, Benitez R, Hove-Madsen L, Napolitano C, Hegele RA, Fill M, Sanatani S, Wilde AAM, Roberts JD, Priori SG, Jensen HK, Chen SRW. Cardiac ryanodine receptor calcium release deficiency syndrome. Sci Transl Med. 2021 Feb 3;13(579):eaba7287.
  5. Dron JS, Wang M, Patel AP, Kartoun U, Ng K, Hegele RA, Khera AV. Genetic Predictor to Identify Individuals With High Lipoprotein(a) Concentrations. Circ Genom Precis Med. 2021 Feb 1:CIRCGEN120003182.
  6. Lazarte J, Dron JS, McIntyre AD, Skanes AC, Gula LJ, Tang AS, Tadros R, Laksman ZW, Hegele RA, Roberts JD. Role of Common Genetic Variation in Lone Atrial Fibrillation. Circ Genom Precis Med. 2021 Feb 1:CIRCGEN120003179.
  7. May SC, Dron JS, Hegele RA, Sahoo D. Human Variant of Scavenger Receptor BI (R174C) Exhibits Impaired Cholesterol Transport Functions. J Lipid Res. 2021 Feb 9:100045.
  8. Lazarte J, Hegele RA. Editorial comment: hazards of interpreting genetic reports. Curr Opin Lipidol. 2021 Feb 16.
  9. Lazarte J, Dron JS, McIntyre AD, Skanes AC, Gula LJ, Tang AS, Tadros R, Laksman ZW, Hegele RA, Roberts JD. Evaluating Polygenic Risk Scores in "Lone" Atrial Fibrillation. CJC Open. 2021 Feb 6;3(6):751-757.
  10. McKenna M, Balasuriya N, Zhong S, Li SS, O'Donoghue P. Phospho-Form Specific Substrates of Protein Kinase B (AKT1). Front Bioeng Biotechnol. 2021 Feb 3;8:619252.
  11. Khan A, Barber DL, Huang J, Rupar CA, Rip JW, Auray-Blais C, Boutin M, O'Hoski P, Gargulak K, McKillop WM, Fraser G, Wasim S, LeMoine K, Jelinski S, Chaudhry A, Prokopishyn N, Morel CF, Couban S, Duggan PR, Fowler DH, Keating A, West ML, Foley R, Medin JA. Lentivirus-mediated gene therapy for Fabry disease. Nat Commun. 2021 Feb 25;12(1):1178.
  12. Siqueira MF, Brothwell D, Heinrichs A, Siqueira WL. Rapid redesign and implementation of new pre-clinic and clinic scheduled model during COVID-19. J Dent Educ. 2021 Feb 26.
  13. Lima IFP, Matos FR, Bernardino ÍM, Santana ITS, Vieira WA, Blumenberg C, Siqueira WL, Paranhos LR. RANK, RANKL, and OPG in Dentigerous Cyst, Odontogenic Keratocyst, and Ameloblastoma: A Meta-Analysis. Braz Dent J. 2021 Jan-Feb;32(1):16-25.

Jan 2021

  1. Haghshenas S, Levy MA, Kerkhof J, Aref-Eshghi E, McConkey H, Balci T, Siu VM, Skinner CD, Stevenson RE, Sadikovic B, Schwartz C. Detection of a DNA Methylation Signature for the Intellectual Developmental Disorder, X-Linked, Syndromic, Armfield Type. Int J Mol Sci. 2021 Jan 23;22(3):1111.
  2. Nouri-Nejad D, O'Donnell BL, Patil CS, Sanchez-Pupo RE, Johnston D, Sayedyahossein S, Jurcic K, Lau R, Gyenis L, Litchfield DW, Jackson MF, Gloor GB, Penuela S. Pannexin 1 mutation found in melanoma tumour reduces phosphorylation, glycosylation, and trafficking of the channel-forming protein. Mol Biol Cell. 2021 Jan 6:mbcE19100585.
  3. Tadros R, Francis C, Xu X, Vermeer AMC, Harper AR, Huurman R, Kelu Bisabu K, Walsh R, Hoorntje ET, Te Rijdt WP, Buchan RJ, van Velzen HG, van Slegtenhorst MA, Vermeulen JM, Offerhaus JA, Bai W, de Marvao A, Lahrouchi N, Beekman L, Karper JC, Veldink JH, Kayvanpour E, Pantazis A, Baksi AJ, Whiffin N, Mazzarotto F, Sloane G, Suzuki H, Schneider-Luftman D, Elliott P, Richard P, Ader F, Villard E, Lichtner P, Meitinger T, Tanck MWT, van Tintelen JP, Thain A, McCarty D, Hegele RA, Roberts JD, Amyot J, Dubé MP, Cadrin-Tourigny J, Giraldeau G, L'Allier PL, Garceau P, Tardif JC, Boekholdt SM, Lumbers RT, Asselbergs FW, Barton PJR, Cook SA, Prasad SK, O'Regan DP, van der Velden J, Verweij KJH, Talajic M, Lettre G, Pinto YM, Meder B, Charron P, de Boer RA, Christiaans I, Michels M, Wilde AAM, Watkins H, Matthews PM, Ware JS, Bezzina CR. Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Nat Genet. 2021 Jan 25.
  4. Hegele RA. Editorial comment: when Mendelian randomization goes astray. Curr Opin Lipidol. 2021 Jan 4.
  5. Cooper TT, Sherman SE, Bell GI, Dayarathna T, McRae DM, Ma J, Lagugné-Labarthet F, Pasternak SH, Lajoie G, Hess DA. Ultrafiltration and Injection of Islet Regenerative Stimuli Secreted by Pancreatic Mesenchymal Stromal Cells. Stem Cells Dev. 2021 Jan 6.
  6. Siddika T, Heinemann IU. Bringing MicroRNAs to Light: Methods for MicroRNA Quantification and Visualization in Live Cells. Front Bioeng Biotechnol. 2021 Jan 18;8:619583. 
  7. Wilson DP, Koschinsky ML, Moriarty PM. Expert position statements: comparison of recommendations for the care of adults and youth with elevated lipoprotein(a). Curr Opin Endocrinol Diabetes Obes. 2021 Jan 28.
  8. Wells CI, Drewry DH, Pickett JE, Tjaden A, Krämer A, Müller S, Gyenis L, Menyhart D, Litchfield DW, Knapp S, Axtman AD. Development of a potent and selective chemical probe for the pleiotropic kinase CK2. Cell Chem Biol. 2021 Jan 11:S2451-9456(20)30522-5.
  9. Penner G, Lecocq S, Chopin A, Vedoya X, Lista S, Vergallo A, Cavedo E, Lejeune FX, Dubois B, Hampel H; INSIGHT-preAD study group; Alzheimer Precision Medicine Initiative (APMI). Aptamarker prediction of brain amyloid-β status in cognitively normal individuals at risk for Alzheimer's disease. PLoS One. 2021 Jan 4;16(1):e0243902. 
  10. Wang Y, Tadayon R, Santamaria L, Mercier P, Forristal CJ, Shaw GS. Calcium binds and rigidifies the dysferlin C2A domain in a tightly coupled manner. Biochem J. 2021 Jan 15;478(1):197-215.
  11. Siqueira MF, Saeed SG, Siqueira WL. Using FacebookTM to increase student engagement. J Dent Educ. 2021 Jan 15.
  12. Rosa V, Ho D, Sabino-Silva R, Siqueira WL, Silikas N. Fighting viruses with materials science: Prospects for antivirus surfaces, drug delivery systems and artificial intelligence. Dent Mater. 2021 Jan 10:S0109-5641(20)30367-5. 
  13. Perampalam P, Hassan HM, Lilly GE, Passos DT, Torchia J, Kiser PK, Bozovic A, Kulasingam V, Dick FA. Disrupting the DREAM transcriptional repressor complex induces apolipoprotein overexpression and systemic amyloidosis in mice. J Clin Invest. 2021 Jan 14:140903.
  14. Walsh JP, DesRochers N, Renaud JB, Seifert KA, Yeung KK, Sumarah MW. Identification of N,N',N″-triacetylfusarinine C as a key metabolite for root rot disease virulence in American ginseng. J Ginseng Res. 2021 Jan;45(1):156-162.
  15. Pinsky W, Harris A, Roseborough AD, Wang W, Khan AR, Jurcic K, Yeung KK, Pasternak SH, Whitehead SN. Regional Lipid Expression Abnormalities Identified Using MALDI IMS Correspond to MRI-Defined White Matter Hyperintensities within Post-mortem Human Brain Tissues. Anal Chem. 2021 Jan 19.