Recent Publications

 picture of Dr. Shawn Li

Jan 2018   Feb 2018   Mar 2018   Apr 2018   May 2018  June 2018   

July 2018   Aug 2018   Sept 2018   Oct 2018   Nov 2018   Dec 2018

Jan 2019   Feb 2019


Feb 2019 

  1. Borrelli MJ, Youssef A, Boffa MB, Koschinsky ML. New Frontiers in Lp(a)-Targeted Therapies. Trends Pharmacol Sci. 2019 Feb 4. pii: S0165-6147(19)30015-X.
  2. Chung CZ, Jaramillo JE, Ellis MJ, Bour DYN, Seidl LE, Jo DHS, Turk MA, Mann MR, Bi Y, Haniford DB,  Duennwald ML, Heinemann IU. RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe. Nucleic Acids Research. 2019 Feb; gkz043.
  3. Hegele RA, Tsimikas S. Lipid-Lowering Agents. Circ Res. 2019 Feb;124(3):386-404.
  4. Rosenson RS, Hegele RA, Koenig W. Cholesterol-Lowering Agents. Circ Res. 2019 Feb;124(3):364-385.
  5. Cho SJ, Ghorbani-Choghamarani A, Saito Y, Hudson RHE. 6-Phenylpyrrolocytidine: An Intrinsically Fluorescent, Environmentally Responsive Nucleoside Analogue. Curr Protoc Nucleic Acid Chem. 2019 Feb 6:e75.
  6. Burke AC, Telford DE, Huff MW. Bempedoic acid: effects on lipoprotein metabolism and atherosclerosis. Curr Opin Lipidol. 2019 Feb;30(1):1-9. 
  7. Bakhtiari M, Konermann L. Protein Ions Generated by Native Electrospray Ionization: Comparison of Gas Phase, Solution, and Crystal Structures. J Phys Chem B. 2019 Feb 6.
  8. Spratt DE, Barber KR, Marlatt NM, Ngo V, Macklin JA, Xiao Y, Konermann L, Duennwald ML, Shaw GS. A Subset of Calcium-binding S100 Proteins Show Preferential Heterodimerization. FEBS J. 2019 Feb 4.
  9. Wei R, Liu X, Voss C, Qin W, Dagnino L, Li L, Vigny M, Li SS. NUMB regulates the endocytosis and activity of the anaplastic lymphoma kinase in an isoform-specific manner. J Mol Cell Biol. 2019 Feb 6.
  10. Wang Y, Tadayon R, Shaw GS. Monitoring Interactions Between S100B and the Dopamine D2 Receptor Using NMR Spectroscopy. Methods Mol Biol. 2019;1929:311-324.

Jan 2019

  1. Boffa MB, Koschinsky ML. Oxidized phospholipids as a unifying theory for lipoprotein(a) and cardiovascular disease. Nat Rev Cardiol. 2019 Jan 23.
  2. Paré G, Caku A, McQueen M, Anand SS, Enas E, Clarke R, Boffa MB, Koschinsky M, Wang X, Yusuf S; INTERHEART Investigators. Lipoprotein(a) Levels and the Risk of Myocardial Infarction Among Seven Ethnic Groups. Circulation. 2019 Jan 22.
  3. Lant JT, Berg MD, Heinemann IU, Brandl CJ, O’Donoghue P. Pathways to disease from natural variations in human cytoplasmic tRNAs. J Biol Chem. 2019 Jan 14. pii: jbc.REV118.002982.
  4. Kim SJ, Asfaha S, Dick FA. CDK4 Inhibitors Thwart Immunity by Inhibiting Phospho-RB-NF-κB Complexes. Mol Cell. 2019 Jan 3;73(1):1-2.
  5. Thwaites MJ, Cecchini MJ, Passos DT, Zakirova K, Dick FA. Context dependent roles for RB-E2F transcriptional regulation in tumor suppression. PLoS One. 2019 Jan 31;14(1):e0203577.
  6. Fernandez ML, Dawson A, Hoenisch J, Kim H, Bamford S, Salamanca C, DiMattia G, Shepherd T, Cremona M, Hennessy B, Anderson S, Volik S, Collins CC, Huntsman DG, Carey MS. Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target. Cancer Cell Int. 2019 Jan 8;19:10.
  7. Joris BR, Gloor GB. Unaccounted risk of cardiovascular disease: the role of the microbiome in lipid metabolism. Curr Opin Lipidol. 2019 Jan 16.
  8. Rosario FJ, Gupta MB, Myatt L, Powell TL, Glenn JP, Cox L, Jansson T. Mechanistic Target of Rapamycin Complex 1 Promotes the Expression of Genes Encoding Electron Transport Chain Proteins and Stimulates Oxidative Phosphorylation in Primary Human Trophoblast Cells by Regulating Mitochondrial Biogenesis. Sci Rep. 2019 Jan 22;9(1):246.
  9. Hegele RA. Editorial: designing targeted sequencing panels for dyslipidemia. Curr Opin Lipidol. 2019 Jan 16.
  10. Dron JS, Hegele RA. The evolution of genetic-based risk scores for lipids and cardiovascular disease. Curr Opin Lipidol. 2019 Jan 22.
  11. Iacocca MA, Dron JS, Hegele RA. Progress in finding pathogenic DNA copy number variations in dyslipidemia. Curr Opin Lipidol. 2019 Jan 16.
  12. Paquette M, Bernard S, Hegele RA, Baass A. Chylomicronemia: Differences between familial chylomicronemia syndrome and multifactorial chylomicronemia. Atherosclerosis. 2018 Dec 28. pii: S0021-9150(18)31550-8.
  13. Hackam DG, Hegele RA. Cholesterol Lowering and Prevention of Stroke. Stroke. 2019 Jan 3:STROKEAHA118023167.
  14. Lazarte J, Hegele RA. Cannabis effects on lipoproteins. Curr Opin Lipidol. 2019 Jan 14.
  15. Karas BJ, Moreau N, Deernick TJ, Gibson DG, Venter JC, Smith H, Glass J. Direct transfer of a Mycoplasma mycoides genome to yeast is enhanced by removal of the mycoides glycerol uptake factor gene glpF. ACS Synth Biol. 2019 Jan 15.
  16. Gordon ZB, Soltysiak MP, Leichthammer C, Therrien JA, Meaney RS, Lauzon C, Adams M, Lee DK, Janakirama P, Lachance MA, Karas BJ. Development of a Transformation Method for Metschnikowia borealis and other CUG-Serine Yeasts. Genes. 2019, 10:78.
  17. Kuljanin M, Elgamal RM, Bell GI, Xenocostas A, Lajoie GA, Hess DA. Human multipotent stromal cell secreted effectors accelerate islet regeneration. Stem Cells. 2019 Jan 23.
  18. Deng J, Liu AD, Hou GQ, Zhang X, Ren K, Chen XZ, Li SSC, Wu YS, Cao X. N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling. J Exp Clin Cancer Res. 2019 Jan 3;38(1):2.
  19. Sancho M, Gao Y, Hald BO, Yin H, Boulton M, Steven D, MacDougall K, Parrent A, Pickering JG, Welsh D. An Assessment of K(IR) Channel Function in Human Cerebral Arteries. Am J Physiol Heart Circ Physiol. 2019 Jan 25.
  20. Dunmore-Buyze PJ, Cruje C, Nong Z, Lee JJ, Kiernan JA, Pickering JG, Drangova M. 3D vessel-wall virtual histology of whole-body perfused mice using a novel heavy element stain. Sci Rep. 2019 Jan 24;9(1):698.
  21. Li Y, Shirley BC, Wilkins RC, Norton F, Knoll JHM, Rogan PK. RADIATION DOSE ESTIMATION BY COMPLETELY AUTOMATED INTERPRETATION OF THE DICENTRIC CHROMOSOME ASSAY. Radiat Prot Dosimetry. 2019 Jan 9.
  22. Mucaki EJ, Zhao JZL, Lizotte DJ, Rogan PK. Predicting responses to platin chemotherapy agents with biochemically-inspired machine learning. Signal Transduct Target Ther. 2019 Jan 11;4:1.
  23. Alkhunaizi E, Shuster S, Shannon P, Siu VM, Darilek S, Mohila CA, Boissel S, Ellezam B, Fallet-Bianco C, Laberge AM, Zandberg J, Injeyan M, Hazrati LN, Hamdan F, Chitayat D. Homozygous/compound heterozygote RYR1 gene variants: Expanding the clinical spectrum. Am J Med Genet A. 2019 Jan 16.
  24. Dowsett L, Porras AR, Kruszka P, Davis B, Hu T, Honey E, Badoe E, Thong MK, Leon E, Girisha KM, Shukla A, Nayak SS, Shotelersuk V, Megarbane A, Phadke S, Sirisena ND, Dissanayake VHW, Ferreira CR, Kisling MS, Tanpaiboon P, Uwineza A, Mutesa L, Tekendo-Ngongang C, Wonkam A, Fieggen K, Batista LC, Moretti-Ferreira D, Stevenson RE, Prijoles EJ, Everman D, Clarkson K, Worthington J, Kimonis V, Hisama F, Crowe C, Wong P, Johnson K, Clark RD, Bird L, Masser-Frye D, McDonald M, Willems P, Roeder E, Saitta S, Anyane-Yeoba K, Demmer L, Hamajima N, Stark Z, Gillies G, Hudgins L, Dave U, Shalev S, Siu V, Ades A, Dubbs H, Raible S, Kaur M, Salzano E, Jackson L, Deardorff M, Kline A, Summar M, Muenke M, Linguraru MG, Krantz ID. Cornelia de Lange syndrome in diverse populations. Am J Med Genet A. 2019 Jan 6.
  25. Krstic M, Kolendowski B, Cecchini MJ, Postenka CO, Hassan HM, Andrews J, MacMillan CD, Williams K, Leong HS, Brackstone M, Torchia J, Chambers AF, Tuck AB. TBX3 promotes progression of pre-invasive breast cancer cells by inducing EMT and directly up-regulating SLUG. J Pathol. 2019 Jan 29.

Dec 2018

  1. Berg MD, Genereaux J, Zhu Y, Mian S, Gloor GB, Brandl CJ. Acceptor Stem Differences Contribute to Species-Specific Use of Yeast and Human tRNA(Ser). Genes (Basel). 2018 Dec 7;9(12). pii: E612.
  2. Gleberzon JS, Liao Y, Mittler S, Goldberg HA, Grohe B. Incorporation of osteopontin peptide into kidney stone-related calcium oxalate monohydrate crystals: a quantitative study. Urolithiasis. 2018 Dec 19. 
  3. Radford BN, Han VKM. Offspring from maternal nutrient restriction in mice show variations in adult glucose metabolism similar to human fetal growth restriction. J Dev Orig Health Dis. 2018 Dec 3:1-10.
  4. Berberich AJ, Hegele RA. The role of genetic testing in dyslipidaemia. Pathology. 2018 Dec 14. pii: S0031-3025(18)30502-6.
  5. Brunham LR, Ruel I, Aljenedil S, Rivière JB, Baass A, Tu JV, Mancini GBJ, Raggi P, Gupta M, Couture P, Pearson GJ, Bergeron J, Francis GA, McCrindle BW, Morrison K, St-Pierre J, Henderson M, Hegele RA, Genest J, Goguen J, Gaudet D, Paré G, Romney J, Ransom T, Bernard S, Katz P, Joy TR, Bewick D, Brophy J. Canadian Cardiovascular Society Position Statement on Familial Hypercholesterolemia: Update 2018. Can J Cardiol. 2018 Dec;34(12):1553-1563.
  6. Ng DM, Burnett JR, Bell DA, Hegele RA, Hooper AJ. Update on the diagnosis, treatment and management of rare genetic lipid disorders. Pathology. 2018 Dec 28. pii: S0031-3025(18)30571-3.
  7. Burnett JR, Hooper AJ, Hegele RA. Lipids and cardiovascular disease. Pathology. 2018 Dec 27. pii: S0031-3025(18)30649-4.
  8. Ho R, McIntyre AD, Kennedy BA, Hegele RA. Whole-exome sequencing identifies a novel IHH insertion in an Ontario family with brachydactyly type A1. SAGE Open Med Case Rep. 2018 Dec 10;6:2050313X18818711.
  9. Paquette M, Bernard S, Hegele RA, Baass A. Chylomicronemia: Differences between familial chylomicronemia syndrome and multifactorial chylomicronemia. Atherosclerosis. 2018 Dec 28. pii: S0021-9150(18)31550-8.
  10. Burke AC, Telford DE, Edwards JY, Sutherland BG, Sawyez CG, Huff MW. Naringenin Supplementation to a Chow Diet Enhances Energy Expenditure and Fatty Acid Oxidation, and Reduces Adiposity in Lean, Pair-Fed Ldlr(-/-) Mice. Mol Nutr Food Res. 2018 Dec 22:e1800833.
  11. Marcovina SM, Moriarty PM, Koschinsky ML, Guyton JR. JCL roundtable-Lipoprotein(a): The emerging risk factor. J Clin Lipidol. 2018 Nov-Dec;12(6):1335-1345.
  12. Talebian A, Robinson-Brookes K, Meakin SO. TrkB Regulates N-Methyl-D-Aspartate Receptor Signaling by Uncoupling and Recruiting the Brain-Specific Guanine Nucleotide Exchange Factor, RasGrf1. J Mol Neurosci. 2018 Dec 13.
  13. El-Sherif O, Xhaferllari I, Sykes J, Butler J, deKemp RA, Renaud J, Yin H, Wilk B, Sullivan R, Pickering JG, Battista J, Wisenberg G, Prato FS, Gaede S. (18)F-FDG Cardiac PET inflammation imaging in a canine model of radiation induced cardiac disease associated with breast cancer radiotherapy. Am J Physiol Heart Circ Physiol. 2018 Dec 21.
  14. Shirley BC, Mucaki EJ and Rogan PK. Pan-cancer repository of validated natural and cryptic mRNA splicing mutations [version 1; referees: 1 approved]. F1000Research 2018, 7:1908.
  15. Lu R and Rogan PK. Transcription factor binding site clusters identify target genes with similar tissue-wide expression and buffer against mutations [version 1; referees: awaiting peer review]. F1000Research 2018, 7:1933.
  16. Abbasi S, Schild-Poulter C. Mapping the Ku interactome using proximity-dependent biotin identification in human cells. J Proteome Res. 2018 Dec 26.
  17. Olson CO, Pejhan S, Kroft D, Sheikholeslami K, Fuss D, Buist M, Ali Sher A, Del Bigio MR, Sztainberg Y, Siu VM, Ang LC, Sabourin-Felix M, Moss T, Rastegar M. MECP2 Mutation Interrupts Nucleolin-mTOR-P70S6K Signaling in Rett Syndrome Patients. Front Genet. 2018 Dec 19;9:635.

Nov 2018

  1. Aref-Eshghi E, Bend EG, Hood RL, Schenkel LC, Carere DA, Chakrabarti R, Nagamani SCS, Cheung SW, Campeau PM, Prasad C, Siu VM, Brady L, Tarnopolsky MA, Callen DJ, Innes AM, White SM, Meschino WS, Shuen AY, Paré G, Bulman DE, Ainsworth PJ, Lin H, Rodenhiser DI, Hennekam RC, Boycott KM, Schwartz CE, Sadikovic B. BAFopathies' DNA methylation epi-signatures demonstrate diagnostic utility and functional continuum of Coffin-Siris and Nicolaides-Baraitser syndromes. Nat Commun. 2018 Nov 20;9(1):4885.
  2. Macklaim JM, Gloor GB. From RNA-seq to Biological Inference: Using Compositional Data Analysis in Meta-Transcriptomics. Methods Mol Biol. 2018;1849:193-213.
  3. Gupta MB, Jansson T. Novel Roles of mTOR Signaling in Regulating Fetal Growth. Biol Reprod. 2018 Nov 21.
  4. Iacocca MA, Chora JR, Carrié A, Freiberger T, Leigh SE, Defesche JC, Kurtz CL, DiStefano MT, Santos RD, Humphries SE, Mata P, Jannes CE, Hooper AJ, Wilemon KA, Benlian P, O'Connor R, Garcia J, Wand H, Tichy L, Sijbrands EJ, Hegele RA, Bourbon M, Knowles JW; ClinGen FH Variant Curation Expert Panel. ClinVar database of global familial hypercholesterolemia-associated DNA variants. Hum Mutat. 2018 Nov;39(11):1631-1640.
  5. Dron JS, Lazarte J, Hegele RA. Recent Highlights of ATVB. Arterioscler Thromb Vasc Biol. 2018 Nov;38(11):e185-e197.
  6. Condos TE, Dunkerley KM, Freeman EA, Barber KR, Aguirre JD, Chaugule VK, Xiao Y, Konermann L, Walden H, Shaw GS. Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO J. 2018 Nov 16. pii: e100014.
  7. Kuljanin M, Elgamal RM, Bell GI, Xenocostas D, Xenocostas A, Hess DA, Lajoie GA. Quantitative Proteomics Evaluation of Human Multipotent Stromal Cell for β Cell Regeneration. Cell Rep. 2018 Nov 27;25(9):2524-2536.e4.
  8. Veggiani G, Huang H, Yates BP, Tong J, Kaneko T, Joshi R, Li SS, Moran MF, Gish G, Sidhu SS. Engineered SH2 domains with tailored specificities and enhanced affinities for phosphoproteome analysis. Protein Sci. 2018 Nov 15.
  9. Zhang A, Tessier TM, Galpin KJC, King CR, Gameiro SF, Anderson WW, Yousef AF, Qin WT, Li SSC, Mymryk JS. The Transcriptional Repressor BS69 is a Conserved Target of the E1A Proteins from Several Human Adenovirus Species. Viruses. 2018 Nov 22;10(12). pii: E662.
  10. Yin H, Akawi O, Fox SA, Li F, O'Neil C, Balint B, Arpino JM, Watson A, Wong J, Guo L, Quantz MA, Nagpal AD, Kiaii B, Chu MWA, Pickering JG. Cardiac-Referenced Leukocyte Telomere Length and Outcomes After Cardiovascular Surgery. JACC Basic Transl Sci. 2018 Nov 12;3(5):591-600.
  11. Atkinson A, Renziehausen A, Wang H, Lo Nigro C, Lattanzio L, Merlano M, Rao B, Weir L, Evans A, Matin R, Harwood C, Szlosarek P, Pickering JG, Fleming C, Sim VR, Li S, Vasta JT, Raines RT, Boniol M, Thompson A, Proby C, Crook T, Syed N. The collagen prolyl hydroxylases are bifunctional growth regulators in melanoma. J Invest Dermatol. 2018 Nov 16. pii: S0022-202X(18)32822-7.

Oct 2018

  1. Watts GF, Boffa MB. Lipoprotein(a): lodestar for future clinical trials. Lancet. 2018 Oct 4. pii: S0140-6736(18)31922-6.
  2. Murcia Rios A, Vahidi S, Dunn SD, Konermann L. Evidence for a Partially Stalled Gamma Rotor in F1-ATPase from H/D Exchange Experiments and Molecular Dynamics Simulations. J Am Chem Soc. 2018 Oct 19.
  3. McMurrough TA, Brown CM, Zhang K, Hausner G, Junop MS, Gloor GB, Edgell DR. Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases. Nucleic Acids Res. 2018 Oct 24.
  4. Geller AS, Polisecki EY, Diffenderfer MR, Asztalos BF, Karathanasis SK, Hegele RA, Schaefer EJ. Genetic and secondary causes of severe HDL deficiency and cardiovascular disease. J Lipid Res. 2018 Oct 17. pii: jlr.M088203.
  5. Kapur A, Singh N, Mete O, Hegele RA, Fantus IG. A Young Male with Parafibromin-Deficient Parathyroid Carcinoma Due to a Rare Germline HRPT2/CDC73 Mutation. Endocr Pathol. 2018 Oct 25. 
  6. Brunham LR, Ruel I, Khoury E, Hegele RA, Couture P, Bergeron J, Baass A, Dufour R, Francis GA, Cermakova L, Mancini GBJ, Brophy JM, Brisson D, Gaudet D, Genest J. Familial hypercholesterolemia in Canada: Initial results from the FH Canada national registry. Atherosclerosis. 2018 Oct;277:419-424.
  7. Corral P, Geller AS, Polisecki EY, Lopez GI, Bañares VG, Cacciagiu L, Berg G, Hegele RA, Schaefer EJ, Schreier LE. Unusual genetic variants associated with hypercholesterolemia in Argentina. Atherosclerosis. 2018 Oct;277:256-261.
  8. Iacocca MA, Wang J, Sarkar S, Dron JS, Lagace T, McIntyre AD, Lau P, Robinson JF, Yang P, Knoll JH, Cao H, McPherson R, Hegele RA. Whole-Gene Duplication of PCSK9 as a Novel Genetic Mechanism for Severe Familial Hypercholesterolemia. Can J Cardiol. 2018 Oct;34(10):1316-1324.
  9. Ho R, Hegele RA. Complex effects of laminopathy mutations on nuclear structure and function. Clin Genet. 2018 Oct 3.
  10. Perera U, Kennedy BA, Hegele RA. Multiple Symmetric Lipomatosis (Madelung Disease) in a Large Canadian Family With the Mitochondrial MTTK c.8344A>G Variant. J Investig Med High Impact Case Rep. 2018 Sep 29;6:2324709618802867.Mancini GBJ, Hegele RA, Leiter LA. Erratum to "Dyslipidemia": Canadian Journal of Diabetes 2018;42(S1):S178-S185. Can J Diabetes. 2018 Oct;42(5):574.
  11. Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A. Reporting Sex and Sex Differences in Preclinical Studies. Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):e171-e184.
  12. Dron JS, Wang J, Cao H, McIntyre AD, Iacocca MA, Menard JR, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Severe hypertriglyceridemia is primarily polygenic. J Clin Lipidol. 2018 Oct 24. pii: S1933-2874(18)30426-4.
  13. Eguchi J, Miyashita K, Fukamachi I, Nakajima K, Murakami M, Kawahara Y, Yamashita T, Ohta Y, Abe K, Nakatsuka A, Mino M, Takase S, Okazaki H, Hegele RA, Ploug M, Hu X, Wada J, Young SG, Beigneux AP. GPIHBP1 autoantibody syndrome during interferon β1a treatment. J Clin Lipidol. 2018 Oct 24. pii: S1933-2874(18)30424-0.
  14. Kaneko T, Stogios PJ, Ruan X, Voss C, Evdokimova E, Skarina T, Chung A, Liu X, Li L, Savchenko A, Ensminger AW, Li SS. Identification and characterization of a large family of superbinding bacterial SH2 domains. Nat Commun. 2018 Oct 31;9(1):4549.
  15. Wu E, Feng K, Shi R, Lv R, Ouyang F, Li SSC, Zhong J, Liu J. Hybrid CuCoO-GO enables ultrasensitive detection of antibiotics with enhanced laser desorption/ionization at nano-interfaces. Chem Sci. 2018 Oct 8;10(1):257-267.
  16. Jha V, Ling H. 2.0-Å resolution crystal structure of human polkappa reveals a new catalytic function of N-clasp in DNA replication. Sci Rep. 2018 Oct 11;8(1):15125. 
  17. Klapak D, Broadfoot S, Penner G, Singh A, Inapuri E. Development of novel aptamers for low-density lipoprotein particle quantification. PLoS One. 2018 Oct 11;13(10):e0205460.
  18. Kim CS, Hannouf MB, Sarma S, Rodrigues GB, Rogan PK, Mahmud SM, Winquist E, Brackstone M, Zaric GS. Survival outcome differences based on treatments used and knowledge of the primary tumour site for patients with cancer of unknown and known primary in Ontario. Curr Oncol. 2018 Oct;25(5):307-316.
  19. Tejada MG, Sudhakar S, Kim NK, Aoyama H, Shilton BH, Bai D. Variants with increased negative electrostatic potential in the Cx50 gap junction pore increased unitary channel conductance and magnesium modulation. Biochem J. 2018 Oct 4. pii: BCJ20180523.
  20. Francisco PA, Delboni MG, Lima AR, Xiao Y, Siqueira WL, Gomes BPFA. Proteomic profile of root canal contents in teeth with post-treatment endodontic disease. Int Endod J. 2018 Oct 4.
  21. Walsh JP, Renaud JB, Hoogstra S, McMullin DR, Ibrahim A, Visagie C, Tanney JB, Yeung KK, Sumarah MW. Diagnostic Fragmentation Filtering for the Discovery of New Chaetoglobosins and Cytochalasins. Rapid Commun Mass Spectrom. 2018 Oct 16.

Sept 2018

  1. Boffa MB, Stranges S, Klar N, Moriarty PM, Watts GF, Koschinsky ML. Lipoprotein(a) and secondary prevention of atherothrombotic events: A critical appraisal. J Clin Lipidol. 2018 Sep 11. pii: S1933-2874(18)30371-4.
  2. Cheng X, Jobin-Robitaille O, Billon P, Buisson R, Niu H, Lacoste N, Abshiru N, Côté V, Thibault P, Kron SJ, Sung P, Brandl CJ, Masson JY, Côté J. Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection. Proc Natl Acad Sci U S A. 2018 Sep 17. pii: 201806513.
  3. Chyzhyk V, Kozmic S, Brown AS, Hudgins LC, Starc TJ, Davila AD, Blevins TC, Diffenderfer MR, He L, Geller AS, Rush C, Hegele RA, Schaefer EJ. Extreme hypertriglyceridemia: Genetic diversity, pancreatitis, pregnancy, and prevalence. J Clin Lipidol. 2018 Sep 18. pii: S1933-2874(18)30405-7.
  4. Xiao Y, Li M, Larocque R, Zhang F, Malhotra A, Chen J, Linhardt RJ, Konermann L, Xu D. Dimerization Interface of Osteoprotegerin Revealed by Hydrogen-deuterium Exchange Mass Spectrometry. J Biol Chem. 2018 Sep 25. pii: jbc.RA118.004489.
  5. Chu B, He A, Tian Y, He W, Chen P, Hu J, Xu R, Zhou W, Zhang M, Yang P, Li SSC, Sun Y, Li P, Hunter T, Tian R. Photoaffinity-engineered protein scaffold for systematically exploring native phosphotyrosine signaling complexes in tumor samples. Proc Natl Acad Sci U S A. 2018 Sep 6.
  6. Walliser C, Wist M, Hermkes E, Zhou Y, Schade A, Haas J, Deinzer J, Désiré L, Li SSC, Stilgenbauer S, Milner JD, Gierschik P. Functional characterization of phospholipase C-γ(2) mutant protein causing both somatic ibrutinib resistance and a germline monogenic autoinflammatory disorder. Oncotarget. 2018 Sep 28;9(76):34357-34378.
  7. Balasuriya N, McKenna M, Liu X, Li SSC, O'Donoghue P. Phosphorylation-Dependent Inhibition of Akt1. Genes (Basel). 2018 Sep 7;9(9). pii: E450.
  8. Burke LJ, Sevcik J, Gambino G, Tudini E, Mucaki EJ, Shirley BC, Whiley P, Parsons MT, De Leeneer K, Gutiérrez-Enríquez S, Santamariña M, Caputo SM, Santana Dos Santos E, Soukupova J, Janatova M, Zemankova P, Lhotova K, Stolarova L, Borecka M, Moles-Fernández A, Manoukian S, Bonanni B; ENIGMA Consortium, Edwards SL, Blok MJ, van Overeem Hansen T, Rossing M, Diez O, Vega A, Claes KBM, Goldgar DE, Rouleau E, Radice P, Peterlongo P, Rogan PK, Caligo M, Spurdle AB, Brown MA. BRCA1 and BRCA2 5' non-coding region variants identified in breast cancer patients alter promoter activity and protein binding. Hum Mutat. 2018 Sep 11.
  9. Huang B, Sadeghinejad L, Adebayo OIA, D M, Xiao Y, Siqueira WL, Cvitkovitch DG, Finer Y. Gene Expression and Protein Synthesis of Esterase from Streptococcus mutans are affected by Biodegradation By-product from Methacrylate Resin Composites and Adhesives. Acta Biomater. 2018 Sep 27. pii: S1742-7061(18)30579-8.
  10. Luo B, Edge AK, Tolg C, Turley EA, Dean CB, Hill KA, Kulperger RJ. Spatial statistical tools for genome-wide mutation cluster detection under a microarray probe sampling system. PLoS One. 2018 Sep 25;13(9):e0204156.
  11. Hauser-Kawaguchi A, Tolg C, Peart T, Milne M, Turley EA, Luyt LG. A truncated RHAMM protein for discovering novel therapeutic peptides. Bioorg Med Chem. 2018 Sep 18. pii: S0968-0896(18)30558-3.
  12. McCarthy JB, El-Ashry D, Turley EA. Corrigendum: Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression. Front Cell Dev Biol. 2018 Sep 24;6:112.

Aug 2018

  1. Pignanelli M, Bogiatzi C, Gloor G, Allen-Vercoe E, Reid G, Urquhart BL, Ruetz KN, Velenosi TJ, Spence JD. Moderate Renal Impairment and Toxic Metabolites Produced by the Intestinal Microbiome: Dietary Implications. J Ren Nutr. 2018 Aug 9. pii: S1051-2276(18)30128-6.
  2. Gupta MB, Abu Shehab M, Nygard K, Biggar K, Singal SS, Santoro N, Powell TL, Jansson T. IUGR is associated with marked hyperphosphorylation of decidual and maternal plasma IGFBP-1. J Clin Endocrinol Metab. 2018 Aug 16.
  3. Baass A, Hegele RA. Getting Real With PCSK9 Inhibitors in Familial Hypercholesterolemia. Can J Cardiol. 2018 Aug;34(8):959-961.
  4. Low-Kam C, Rhainds D, Lo KS, Barhdadi A, Boulé M, Alem S, Pedneault-Gagnon V, Rhéaume E, Dubé MP, Busseuil D, Hegele RA, Lettre G, Tardif JC. Variants at the APOE /C1/C2/C4 Locus Modulate Cholesterol Efflux Capacity Independently of High-Density Lipoprotein Cholesterol. J Am Heart Assoc. 2018 Aug 21;7(16):e009545.
  5. Buzon B, Grainger R, Huang S, Rzadki C, Junop MS. Structure-specific endonuclease activity of SNM1A enables processing of a DNA interstrand crosslink. Nucleic Acids Res. 2018 Aug 27.
  6. Albatany M, Meakin S, Bartha R. The Monocarboxylate transporter inhibitor Quercetin induces intracellular acidification in a mouse model of Glioblastoma Multiforme: in-vivo detection using magnetic resonance imaging. Invest New Drugs. 2018 Aug 13.
  7. O'Donoghue P, Ling J, Söll D. Transfer RNA function and evolution. RNA Biol. 2018;15(4-5):423-426.
  8. Caughlin S, Hepburn J, Liu Q, Wang L, Yeung KK, Cechetto DF, Whitehead SN. Chloroquine Restores Ganglioside Homeostasis and Improves Pathological and Behavioral Outcomes Post-stroke in the Rat. Mol Neurobiol. 2018 Aug 25.

July 2018

  1. Romagnuolo R, DeMarco K, Scipione CA, Boffa MB, Koschinsky ML. Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells. Thromb Res. 2018 Jul 4;169:1-7.
  2. Pereira CV, Bacman SR, Arguello T, Zekonyte U, Williams SL, Edgell DR, Moraes CT. mitoTev-TALE: a monomeric DNA editing enzyme to reduce mutant mitochondrial DNA levels. EMBO Mol Med. 2018 Jul 16. pii: e8084.
  3. Berberich AJ, Hegele RA. The complex molecular genetics of familial hypercholesterolaemia. Nat Rev Cardiol. 2018 Jul 4.
  4. Wang LR, Radonjic A, Dilliott AA, McIntyre AD, Hegele RA. A De Novo POLD1 Mutation Associated With Mandibular Hypoplasia, Deafness, Progeroid Features, and Lipodystrophy Syndrome in a Family With Werner Syndrome. J Investig Med High Impact Case Rep. 2018 Jul 12;6:2324709618786770.
  5. Rosenson RS, Hegele RA, Fazio S, Cannon CP. The Evolving Future of PCSK9 Inhibitors. J Am Coll Cardiol. 2018 Jul 17;72(3):314-329. Burke AC, Sutherland BG, Telford DE, Morrow MR, Sawyez CG, Edwards JY, Drangova M, Huff MW. Intervention with citrus flavonoids reverses obesity, and improves metabolic syndrome and atherosclerosis in obese Ldlr-/- mice. J Lipid Res. 2018 Jul 15. pii: jlr.M087387.
  6. Xiao Y, Shaw GS, Konermann L. Correction to "Calcium-Mediated Control of S100 Proteins: Allosteric Communication via an Agitator/Signal Blocking Mechanism". J Am Chem Soc. 2018 Jul 5.
  7. Duez Q, Metwally H, Konermann L. Electrospray Ionization of Polypropylene Glycol: Rayleigh-Charged Droplets, Competing Pathways, and Charge State-Dependent Conformations. Anal Chem. 2018 Jul 19.
  8. Metwally H, Duez Q, Konermann L. Chain Ejection Model for Electrospray Ionization of Unfolded Proteins: Evidence from Atomistic Simulations and Ion Mobility Spectrometry. Anal Chem. 2018 Jul 24.
  9. Liu AD, Xu H, Gao YN, Luo DN, Li ZF, Voss C, Li SSC, Cao X. (Arg)(9)-SH2 superbinder: a novel promising anticancer therapy to melanoma by blocking phosphotyrosine signaling. J Exp Clin Cancer Res. 2018 Jul 5;37(1):138.
  10. Bowie LE, Maiuri T, Alpaugh M, Gabriel M, Arbez N, Galleguillos D, Hung CLK, Patel S, Xia J, Hertz NT, Ross CA, Litchfield DW, Sipione S, Truant R. N6-Furfuryladenine is protective in Huntington's disease models by signaling huntingtin phosphorylation. Proc Natl Acad Sci U S A. 2018 Jul 9. pii: 201801772. 

June 2018

  1. Rowland ME, Jiang Y, Beier F, Bérubé NG. Inactivation of hepatic ATRX in Atrx Foxg1cre mice prevents reversal of aging-like phenotypes by thyroxine. Aging (Albany NY). 2018 Jun 7.
  2. Zarghami N, Murrell DH, Jensen MD, Dick FA, Chambers AF, Foster PJ, Wong E. Half brain irradiation in a murine model of breast cancer brain metastasis: magnetic resonance imaging and histological assessments of dose-response. Radiat Oncol. 2018 Jun 1;13(1):104.
  3. Pignanelli M, Just C, Bogiatzi C, Dinculescu V, Gloor GB, Allen-Vercoe E, Reid G, Urquhart BL, Ruetz KN, Velenosi TJ, Spence JD. Mediterranean Diet Score: Associations with Metabolic Products of the Intestinal Microbiome, Carotid Plaque Burden, and Renal Function. Nutrients. 2018 Jun 16;10(6). pii: E779.
  4. McMillan A, Rulisa S, Gloor GB, Macklaim JM, Sumarah M, Reid G. Pilot assessment of probiotics for pregnant women in Rwanda. PLoS One. 2018 Jun 18;13(6):e0195081.
  5. Petrova MI, Macklaim JM, Wuyts S, Verhoeven T, Vanderleyden J, Gloor GB, Lebeer S, Reid G. Comparative Genomic and Phenotypic Analysis of the Vaginal Probiotic Lactobacillus rhamnosus GR-1. Front Microbiol. 2018 Jun 15;9:1278.
  6. Chen YY, Gupta MB, Grattton R, Powell TL, Jansson T. Down-regulation of placental folate transporters in intrauterine growth restriction. J Nutr Biochem. 2018 Jun 11;59:136-141.
  7. Daugherty A, Lu HS, Hegele RA, Mackman N, Rader DJ, Schmidt AM, Weber C. Response by Daugherty et al to Letter Regarding Article, "Consideration of Sex Differences in Design and Reporting of Experimental Arterial Pathology Studies: A Statement From the Arteriosclerosis, Thrombosis, and Vascular Biology Council". Arterioscler Thromb Vasc Biol. 2018 Jun;38(6):e101-e102.
  8. Dron JS, Wang J, Berberich AJ, Iacocca MA, Cao H, Yang P, Knoll J, Tremblay K, Brisson D, Netzer C, Gouni-Berthold I, Gaudet D, Hegele RA. Large-scale deletions of the ABCA1 gene in patients with hypoalphalipoproteinemia. J Lipid Res. 2018 Jun 4. pii: jlr.P086280.
  9. Wójcik C, Fazio S, McIntyre AD, Hegele RA. Co-occurrence of heterozygous CREB3L3 and APOA5 nonsense variants and polygenic risk in a patient with severe hypertriglyceridemia exacerbated by estrogen administration. J Clin Lipidol. 2018 Jun 1. pii: S1933-2874(18)30243-5.
  10. Turk MA, Chung CZ, Manni E, Zukowski SA, Engineer A, Badakhshi Y, Bi Y, Heinemann IU. MiRAR-miRNA Activity Reporter for Living Cells. Genes (Basel). 2018 Jun 19;9(6). pii: E305.
  11. Qiu B, Al K, Pena-Diaz AM, Athwal GS, Drosdowech D, Faber KJ, Burton JP, O'Gorman DB. Cutibacterium acnes and the shoulder microbiome. J Shoulder Elbow Surg. 2018 Jun 13. pii: S1058-2746(18)30304-5.

May 2018

  1. Kotsopoulos J, Gronwald J, Lynch HT, Eisen A, Neuhausen SL, Tung N, Ainsworth P, Weitzel JN, Pal T, Foulkes WD, Eng C, Singer CF, Senter L, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Age at first full-term birth and breast cancer risk in BRCA1 and BRCA2 mutation carriers. Breast Cancer Res Treat. 2018 May 17.
  2. Kotsopoulos J, Gronwald J, Karlan B, Rosen B, Huzarski T, Moller P, Lynch HT, Singer CF, Senter L, Neuhausen SL, Tung N, Eisen A, Foulkes WD, Ainsworth P, Sun P, Lubinski J, Narod SA; Hereditary Ovarian Cancer Clinical Study Group. Age-specific ovarian cancer risks among women with a BRCA1 or BRCA2 mutation. Gynecol Oncol. 2018 May 21. pii: S0090-8258(18)30898-9.
  3. Romagnuolo R, Scipione CA, Bazzi ZA, Boffa MB, Koschinsky ML. Inhibition of pericellular plasminogen activation by apolipoprotein(a): Roles of urokinase plasminogen activator receptor and integrins αMβ2 and αVβ3. Atherosclerosis. 2018 May 17;275:11-21.
  4. Karttunen M, Choy WY, Cino EA. Prediction of Binding Energy of Keap1 Interaction Motifs in the Nrf2 Antioxidant Pathway and Design of Potential High Affinity Peptides. J Phys Chem B. 2018 May 10.
  5. Gloor GB, Wong RG, Allen-Vercoe E, Dinculescu V, Pignanelli M, Bogiatzi C, Reid G, Spence JD. Data on the gut and saliva microbiota from a cohort of atherosclerosis patients determined by 16S rRNA gene sequencing. Data Brief. 2018 May 11;19:481-485.
  6. Plouffe RA, Hammond R, Goldberg HA, Chahine S. What Matters from Admissions? Identifying Success and Risk Among Canadian Dental Students. J Dent Educ. 2018 May;82(5):515-523.
  7. Singal SS, Nygard K, Gratton R, Jansson T, Gupta MB. Increased Insulin-like Growth Factor Binding Protein-1 Phosphorylation in Decidualized Stromal Mesenchymal Cells in Human Intrauterine Growth Restriction Placentas. J Histochem Cytochem. 2018 May 1:22155418772574.
  8. Mancini GBJ, Hegele RA. Can We Eliminate Low-Density Lipoprotein Cholesterol-Related Cardiovascular Events Through More Aggressive Primary Prevention Therapy? Can J Cardiol. 2018 May;34(5):546-551.
  9. Paquette M, Hegele RA, Baass A. PCSK9 inhibitors in familial hypercholesterolemia: What is the evidence? J Clin Lipidol. 2018 May 26. pii: S1933-2874(18)30238-1.
  10. Feldman RD, Fitchett D, Hegele RA, Poulter NR. Type 2 Diabetes and the Reduction of Cardiovascular Risk: Sorting Out the Actors and the Roles. Can J Cardiol. 2018 May;34(5):532-535.
  11. Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Padwal RS, Tran KC, Grover S, Rabkin SW, Moe GW, Howlett JG, Lindsay P, Hill MD, Sharma M, Field T, Wein TH, Shoamanesh A, Dresser GK, Hamet P, Herman RJ, Burgess E, Gryn SE, Grégoire JC, Lewanczuk R, Poirier L, Campbell TS, Feldman RD, Lavoie KL, Tsuyuki RT, Honos G, Prebtani APH, Kline G, Schiffrin EL, Don-Wauchope A, Tobe SW, Gilbert RE, Leiter LA, Jones C, Woo V, Hegele RA, Selby P, Pipe A, McFarlane PA, Oh P, Gupta M, Bacon SL, Kaczorowski J, Trudeau L, Campbell NRC, Hiremath S, Roerecke M, Arcand J, Ruzicka M, Prasad GVR, Vallée M, Edwards C, Sivapalan P, Penner SB, Fournier A, Benoit G, Feber J, Dionne J, Magee LA, Logan AG, Côté AM, Rey E, Firoz T, Kuyper LM, Gabor JY, Townsend RR, Rabi DM, Daskalopoulou SS; Hypertension Canada. Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. Can J Cardiol. 2018 May;34(5):506-525.
  12. Ruel I, Brisson D, Aljenedil S, Awan Z, Baass A, Bélanger A, Bergeron J, Bewick D, Brophy JM, Brunham LR, Couture P, Dufour R, Francis GA, Frohlich J, Gagné C, Gaudet D, Grégoire JC, Gupta M, Hegele RA, Mancini GBJ, McCrindle BW, Pang J, Raggi P, Tu JV, Watts GF, Genest J. Simplified Canadian Definition for Familial Hypercholesterolemia. Can J Cardiol. 2018 May 19. pii: S0828-282X(18)30383-0.
  13. Cvetkovska M, Szyszka-Mroz B, Possmayer M, Pittock P, Lajoie G, Smith DR, Hüner NPA. Characterization of photosynthetic ferredoxin from the Antarctic alga Chlamydomonas sp. UWO241 reveals novel features of cold adaptation. New Phytol. 2018 May 8.
  14. Balasuriya N, Kunkel MT, Liu X, Biggar KK, Li SS, Newton AC, O'Donoghue P. Genetic code expansion and live cell imaging reveal that Thr308 phosphorylation is irreplaceable and sufficient for Akt1 activity. J Biol Chem. 2018 May 17. pii: jbc.RA118.002357.
  15. Albatany M, Li A, Meakin S, Bartha R. In vivo detection of acute intracellular acidification in glioblastoma multiforme following a single dose of cariporide. Int J Clin Oncol. 2018 May 10.
  16. Grishin AM, Barber KR, Gu RX, Peter Tieleman D, Shaw GS, Cygler M. Regulation of Shigella Effector Kinase OspG through Modulation of its Dynamic Properties. J Mol Biol. 2018 May 16. pii: S0022-2836(18)30419-4.
  17. McCarthy JB, El-Ashry D, Turley EA. Hyaluronan, Cancer-Associated Fibroblasts and the Tumor Microenvironment in Malignant Progression. Front Cell Dev Biol. 2018 May 8;6:48.
  18. Morrison LM, Renaud JB, Sabourin L, Sumarah MW, Yeung KKC, Lapen DR. High-Throughput Quantitation of Neonicotinoids in Lyophilized Surface Water by LC-APCI-MS/MS. J AOAC Int. 2018 May 21.

Apr 2018

  1. Aref-Eshghi E, Schenkel LC, Ainsworth P, Lin H, Rodenhiser DI, Cutz JC, Sadikovic B. Genomic DNA Methylation-Derived Algorithm Enables Accurate Detection of Malignant Prostate Tissues. Front Oncol. 2018 Apr 23;8:100.
  2. Berg MD, Genereaux J, Karagiannis J, Brandl CJ. The Pseudokinase Domain of Saccharomyces cerevisiae Tra1 Is Required for Nuclear Localization and Incorporation into the SAGA and NuA4 Complexes. G3 (Bethesda). 2018 Apr 6. pii:g3.200288.2018.
  3. Dick FA, Goodrich DW, Sage J, Dyson NJ. Non-canonical functions of the RB protein in cancer. Nat Rev Cancer. 2018 Apr 24.
  4. Bogiatzi C, Gloor G, Allen-Vercoe E, Reid G, Wong RG, Urquhart BL, Dinculescu V, Ruetz KN, Velenosi TJ, Pignanelli M, Spence JD. Metabolic products of the intestinal microbiome and extremes of atherosclerosis. Atherosclerosis. 2018 Apr 17;273:91-97.
  5. Hegele RA, Berberich AJ, Ban MR, Wang J, Digenio A, Alexander VJ, D'Erasmo L, Arca M, Jones A, Bruckert E, Stroes ES, Bergeron J, Civeira F, Witztum JL, Gaudet D. Clinical and biochemical features of different molecular etiologies of familial chylomicronemia. J Clin Lipidol. 2018 Apr 4. pii: S1933-2874(18)30198-3.
  6. Parajuli RP, Goodrich JM, Chan LHM, Ayotte P, Lemire M, Hegele RA, Basu N. Genetic polymorphisms are associated with exposure biomarkers for metals and persistent organic pollutants among Inuit from the Inuvialuit Settlement Region, Canada. Sci Total Environ. 2018 Apr 7;634:569-578.
  7. Diabetes Canada Clinical Practice Guidelines Expert Committee, Mancini GBJ, Hegele RA, Leiter LA. Dyslipidemia. Can J Diabetes. 2018 Apr;42 Suppl 1:S178-S185.
  8. Dilliott AA, Farhan SMK, Ghani M, Sato C, Liang E, Zhang M, McIntyre AD, Cao H, Racacho L, Robinson JF, Strong MJ, Masellis M, Bulman DE, Rogaeva E, Lang A, Tartaglia C, Finger E, Zinman L, Turnbull J, Freedman M, Swartz R, Black SE, Hegele RA. Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease. J Vis Exp. 2018 Apr 4;(134).
  9. Mach F, Ray KK, Wiklund O, Corsini A, Catapano AL, Bruckert E, De Backer G, Hegele RA, Hovingh GK, Jacobson TA, Krauss RM, Laufs U, Leiter LA, März W, Nordestgaard BG, Raal FJ, Roden M, Santos RD, Stein EA, Stroes ES, Thompson PD, Tokgözoglu L, Vladutiu GD, Gencer B, Stock JK, Ginsberg HN, Chapman MJ; European Atherosclerosis Society Consensus Panel. Adverse effects of statin therapy: perception vs. the evidence - focus on glucose homeostasis, cognitive, renal and hepatic function, haemorrhagic stroke and cataract. Eur Heart J. 2018 Apr 27.
  10. Konermann L, Metwally H, McAllister RG, Popa V. How to Run Molecular Dynamics Simulations on Electrospray Droplets and Gas Phase Proteins: Basic Guidelines and Selected Applications. Methods. 2018 Apr 17. pii: S1046-2023(17)30464-4.
  11. Jha V, Ling H. Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. J Mol Biol. 2018 Apr 28. pii: S0022-2836(18)30296-1.
  12. Abdallah MN, Abughanam G, Tran SD, Sheikh Z, Mezour MA, Basiri T, Xiao Y, Cerruti M, Siqueira WL, Tamimi F. Comparative adsorption profiles of basal lamina proteome and gingival cells onto dental and titanium surfaces. Acta Biomater. 2018 Apr 13. pii: S1742-7061(18)30220-4.

Mar 2018

  1. Boffa MB, Koschinsky ML. The journey towards understanding lipoprotein(a) and cardiovascular disease risk: are we there yet? Curr Opin Lipidol. 2018 Mar 9.
  2. Wang LR, McIntyre AD, Hegele RA. Complex genetic architecture in severe hypobetalipoproteinemia. Lipids Health Dis. 2018 Mar 14;17(1):48.
  3. McQuaid JB, Kustka AB, Oborník M, Horák A, McCrow JP, Karas BJ, Zheng H, Kindeberg T, Andersson AJ, Barbeau KA, Allen AE. Carbonate-sensitive phytotransferrin controls high-affinity iron uptake in diatoms. Nature. 2018 Mar 14.
  4. Aguirre JD, Dunkerley KM, Lam R, Rusal M, Shaw GS. Impact of altered phosphorylation on loss of function of juvenile Parkinsonism-associated genetic variants of the E3 ligase parkin. J Biol Chem. 2018 Mar 12. pii: jbc.RA117.000605.
  5. Tikhonova S, Booij L, D'Souza V, Crosara KTB, Siqueira WL, Emami E. Investigating the association between stress, saliva and dental caries: a scoping review. BMC Oral Health. 2018 Mar 13;18(1):41.
  6. Jarrett P, Easton A, Rockwood K, Dyack S, McCollum A, Siu V, Mirsattari SM, Massot-Tarrús A, Beis MJ, D'Souza N, Darvesh S. Evidence for Cholinergic Dysfunction in Autosomal Dominant Kufs Disease. Can J Neurol Sci. 2018 Mar;45(2):150-157.
  7. Caughlin S, Maheshwari S, Agca Y, Agca C, Harris AJ, Jurcic K, Yeung KK, Cechetto DF, Whitehead SN. Membrane-lipid homeostasis in a prodromal rat model of Alzheimer's disease: Characteristic profiles in ganglioside distributions during aging detected using MALDI imaging mass spectrometry. Biochim Biophys Acta. 2018 Mar 12. pii: S0304-4165(18)30073-4.
  8. Wang JSH, Freitas-Andrade M, Bechberger JF, Naus C, Yeung KK, Whitehead SN. MALDI IMS of Intraperitoneally Injected Danegaptide (ZP1609) for Treatment of Stroke-Reperfusion Injury in Mice. Rapid Commun Mass Spectrom. 2018 Mar 25.

Feb 2018

  1. Schenkel LC, Aref-Eshghi E, Skinner C, Ainsworth P, Lin H, Paré G, Rodenhiser DI, Schwartz C, Sadikovic B. Peripheral blood epi-signature of Claes-Jensen syndrome enables sensitive and specific identification of patients and healthy carriers with pathogenic mutations in KDM5C. Clin Epigenetics. 2018 Feb 14;10:21.
  2. Boffa MB, Koschinsky ML. Therapeutic Lowering of Lipoprotein(a): A Role for Pharmacogenetics? Circ Genom Precis Med. 2018 Feb;11(2):e002052.
  3. Ishak CA, Cecchini MJ, Howlett CJ, Dick FA. Immunohistochemical Detection of the Retinoblastoma Protein. Methods Mol Biol. 2018;1726:65-75.
  4. Egozcue JJ, Pawlowsky-Glahn V, Gloor GB. Linear Association in Compositional Data Analysis. Austrian J Stats. 2018 Feb;47:3.
  5. Chassen SS, Ferchaud-Roucher V, Gupta MB, Jansson T, Powell TL. Alterations in Placental Long Chain Polyunsaturated Fatty Acid Metabolism in Human Intrauterine Growth Restriction. Clin Sci (Lond). 2018 Feb 20. pii: CS20171340.
  6. Linke AC, Wild C, Zubiaurre-Elorza L, Herzmann C, Duffy H, Han VK, Lee DSC, Cusack R. Disruption to functional networks in neonates with perinatal brain injury predicts motor skills at 8 months. Neuroimage Clin. 2018 Feb 3;18:399-406.
  7. Berberich AJ, Hegele RA. Secondary causes of chylomicronemia: defining the underside of the iceberg. J Intern Med. 2018 Feb 2.
  8. Berberich AJ, Ho R, Hegele RA. Whole genome sequencing in the clinic: empowerment or too much information? CMAJ. 2018 Feb 5;190(5):E124-E125.
  9. Yanagi M, Suzuki A, Hudson RHE, Saito Y. A fluorescent 3,7-bis-(naphthalen-1-ylethynylated)-2'-deoxyadenosine analogue reports thymidine in complementary DNA by a large emission Stokes shift. Org Biomol Chem. 2018 Feb 8.
  10. Burke AC, Telford DE, Sutherland BG, Edwards JY, Sawyez CG, Barrett PHR, Newton RS, Pickering JG, Huff MW. Bempedoic Acid Lowers Low-Density Lipoprotein Cholesterol and Attenuates Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient (LDLR(+/-) and LDLR(-/-) ) Yucatan Miniature Pigs. Arterioscler Thromb Vasc Biol. 2018 Feb 15. pii: ATVBAHA.117.310676.
  11. Leighton TL, Mok MC, Junop MS, Howell PL, Burrows LL. Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function. Sci Rep. 2018 Feb 8;8(1):2600.
  12. Metwally H, Konermann L. Crown Ethers Modulate the Location of Charge Carriers in Electrospray Droplets: Implications for the Mechanism of Protein Charging and Supercharging. Anal Chem. 2018 Feb 28.
  13. Yin H, Pickering JG. Aortic smooth muscle cells and myocardial infarction: Does the ascending aorta feel a heart attack? Atherosclerosis. 2018 Feb 10. pii: S0021-9150(18)30080-7.
  14. Zhao JZL, Mucaki EJ and Rogan PK. Predicting ionizing radiation exposure using biochemically-inspired genomic machine learning [version 1; referees: awaiting peer review]. F1000Research 2018, 7:233.
  15. Brady L, Sadikovic B, Rupar CA, Tarnopolsky MA. Complete elimination of a pathogenic homoplasmic mtDNA mutation in one generation. Mitochondrion. 2018 Feb 1. pii: S1567-7249(17)30328-8.
  16. Huang B, Siqueira W, Cvitkovitch DG, Finer Y. Esterase from a Cariogenic Bacterium Hydrolyzes Dental Resins. Acta Biomater. 2018 Feb 26. pii: S1742-7061(18)30091-6.
  17. Valente MT, Moffa EB, Crosara KTB, Xiao Y, de Oliveira TM, Machado MAAM, Siqueira WL. Acquired Enamel Pellicle Engineered Peptides: Effects on Hydroxyapatite Crystal Growth. Sci Rep. 2018 Feb 28;8(1):3766.
  18. Zarate YA, Smith-Hicks CL, Greene C, Abbott MA, Siu VM, Calhoun ARUL, Pandya A, Li C, Sellars EA, Kaylor J, Bosanko K, Kalsner L, Basinger A, Slavotinek AM, Perry H, Saenz M, Szybowska M, Wilson LC, Kumar A, Brain C, Balasubramanian M, Dubbs H, Ortiz-Gonzalez XR, Zackai E, Stein Q, Powell CM, Schrier Vergano S, Britt A, Sun A, Smith W, Bebin EM, Picker J, Kirby A, Pinz H, Bombei H, Mahida S, Cohen JS, Fatemi A, Vernon HJ, McClellan R, Fleming LR, Knyszek B, Steinraths M,  Velasco Gonzalez C, Beck AE, Golden-Grant KL, Egense A, Parikh A, Raimondi C, Angle B, Allen W, Schott S, Algrabli A, Robin NH, Ray JW, Everman DB, Gambello MJ, Chung WK. Natural history and genotype-phenotype correlations in 72 individuals with SATB2-associated syndrome. Am J Med Genet A. 2018 Feb 13.
  19. Wang JS, Whitehead SN, Yeung KK. Detection of Amyloid Beta (Aβ) Oligomeric Composition Using Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS). J Am Soc Mass Spectrom. 2018 Feb 20.

Jan 2018

  1. Aref-Eshghi E, Rodenhiser DI, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Hood RL, Bulman DE, Kernohan KD; Care4Rare Canada Consortium, Boycott KM, Campeau PM, Schwartz C, Sadikovic B. Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes. Am J Hum Genet. 2018 Jan 4;102(1):156-174.
  2. Mohamed HT, El-Husseiny N, El-Ghonaimy EA, Ibrahim SA, Bazzi ZA, Cavallo-Medved D, Boffa MB, El-Shinawi M, Mohamed MM. IL-10 correlates with the expression of carboxypeptidase B2 and lymphovascular invasion in inflammatory breast cancer: The potential role of tumor infiltrated macrophages. Curr Probl Cancer. 2018 Jan 10. pii: S0147-0272(17)30120-4.
  3. Slattery SS, Diamond A, Wang H, Therrien JA, Lant JT, Jazey T, Lee K, Klassen Z, Desgagné-Penix I, Karas BJ, Edgell DR. An expanded plasmid-based genetic toolbox enables Cas9 genome editing and stable maintenance of synthetic pathways in Phaeodactylum tricornutum. ACS Synth Biol. 2018 Jan 3.
  4. Kaiser JC, King AN, Grigg JC, Sheldon JR, Edgell DR, Murphy MEP, Brinsmade SR, Heinrichs DE. Repression of branched-chain amino acid synthesis in Staphylococcus aureus is mediated by isoleucine via CodY, and by a leucine-rich attenuator peptide. PLoS Genet. 2018 Jan 22;14(1):e1007159.
  5. Zubiaurre-Elorza L, Linke AC, Herzmann C, Wild CJ, Duffy H, Lee DSC, Han VK, Cusack R. Auditory structural connectivity in preterm and healthy term infants during the first postnatal year. Dev Psychobiol. 2018 Jan 22.
  6. Aboalola D, Han VKM. Different Effects of Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor-2 on Myogenic Differentiation of Human Mesenchymal Stem Cells. Stem Cells Int. 2017;2017:8286248.
  7. Iacocca MA, Hegele RA. Role of DNA copy number variation in dyslipidemias. Curr Opin Lipidol. 2018 Jan 4.
  8. Clemens KK, Shariff SZ, McArthur E, Hegele RA. Ezetimibe prescriptions in older Canadian adults after an acute myocardial infarction: a population-based cohort study. Lipids Health Dis. 2018 Jan 8;17(1):8.
  9. Dron JS, Hegele RA. Polygenic influences on dyslipidemias. Curr Opin Lipidol. 2018 Jan 2.
  10. Hegele RA. Learning From Patients With Ultrarare Conditions: Cholesterol Hoof Beats. J Am Coll Cardiol. 2018 Jan 23;71(3):289-291.
  11. Paquette M, Hegele RA, Paré G, Baass A. A novel mutation in GPIHBP1 causes familial chylomicronemia syndrome. J Clin Lipidol. 2018 Jan 31. pii: S1933-2874(18)30031-X.
  12. Snir JA, Suchy M, Bindseil GA, Kovacs M, Chronik BA, Hudson RHE, Pasternak SH, Bartha R. An Aspartyl Cathepsin Targeted PET Agent: Application in an Alzheimer's Disease Mouse Model. J Alzheimers Dis. 2018;61(3):1241-1252.
  13. Morrow NM, Huff MW. Knockdown of Δ-5 Fatty Acid Desaturase Is More Than Just a Fad. Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):6-8.
  14. Burke AC, Huff MW. Regression of atherosclerosis: lessons learned from genetically modified mouse models. Curr Opin Lipidol. 2018 Jan 24.
  15. Tsimikas S, Fazio S, Ferdinand KC, Ginsberg HN, Koschinsky ML, Marcovina SM, Moriarty PM, Rader DJ, Remaley AT, Reyes-Soffer G, Santos RD, Thanassoulis G, Witztum JL, Danthi S, Olive M, Liu L. NHLBI Working Group Recommendations to Reduce Lipoprotein(a)-Mediated Risk of Cardiovascular Disease and Aortic Stenosis. J Am Coll Cardiol. 2018 Jan 16;71(2):177-192.
  16. Cooper TT, Sherman SE, Kuljanin M, Bell GI, Lajoie GA, Hess DA. Inhibition Of Aldehyde Dehydrogenase-Activity Expands Multipotent Myeloid Progenitor Cells With Vascular Regenerative Function. Stem Cells. 2018 Jan 27.
  17. Lecocq S, Spinella K, Dubois B, Lista S, Hampel H, Penner G. Aptamers as biomarkers for neurological disorders. Proof of concept in transgenic mice. PLoS One. 2018 Jan 5;13(1):e0190212.
  18. O'Connor K, Jukes T, Goobie S, DiRaimo J, Moran G, Potter BK, Chakraborty P, Rupar CA, Gannavarapu S, Prasad C. Psychosocial impact on mothers receiving expanded newborn screening results. Eur J Hum Genet. 2018 Jan 29.
  19. Datar R, Prasad AN, Tay KY, Rupar CA, Ohorodnyk P, Miller M, Prasad C. Magnetic resonance imaging in the diagnosis of white matter signal abnormalities. Neuroradiol J. 2018 Jan 1:1971400918764016.
  20. Crosara KTB, Zuanazzi D, Moffa EB, Xiao Y, Machado MAAM, Siqueira WL. Revealing the Amylase Interactome in Whole Saliva Using Proteomic Approaches. Biomed Res Int. 2018 Jan 31;2018:6346954.
  21. Kolendowski B, Hassan H, Krstic M, Isovic M, Thillainadesan G, Chambers AF, Tuck AB, Torchia J. Genome-wide analysis reveals a role for TDG in estrogen receptor-mediated enhancer RNA transcription and 3-dimensional reorganization. Epigenetics Chromatin. 2018 Jan 29;11(1):5. 
  22. Hauser-Kawaguchi A, Luyt LG, Turley E. Design of peptide mimetics to block pro-inflammatory functions of HA fragments. Matrix Biol. 2018 Jan 30. pii: S0945-053X(17)30444-4.