Recent Publications

picture of Dr. Shawn Li

2020

Jan 2020   Feb 2020   Mar 2020   Apr 2020   May 2020   June2020

July 2020   Aug 2020   Sept 2020   Oct 2020

Archives


Oct 2020

  1. Yin V, Holzscherer D, Konermann L. Delineating Heme-Mediated versus Direct Protein Oxidation in Peroxidase-Activated Cytochrome c by Top-Down Mass Spectrometry. Biochemistry. 2020 Oct 5.
  2. Dutta I, Dieters-Castator D, Papatzimas JW, Medina A, Schueler J, Derksen DJ, Lajoie G, Postovit LM, Siegers GM. ADAM protease inhibition overcomes resistance of breast cancer stem-like cells to γδ T cell immunotherapy. Cancer Lett. 2020 Oct 9:S0304-3835(20)30535-8.
  3. Isho B, Abe KT, Zuo M, Jamal AJ, Rathod B, Wang JH, Li Z, Chao G, Rojas OL, Bang YM, Pu A, Christie-Holmes N, Gervais C, Ceccarelli D, Samavarchi-Tehrani P, Guvenc F, Budylowski P, Li A, Paterson A, Yue FY, Marin LM, Caldwell L, Wrana JL, Colwill K, Sicheri F, Mubareka S, Gray-Owen SD, Drews SJ, Siqueira WL, Barrios-Rodiles M, Ostrowski M, Rini JM, Durocher Y, McGeer AJ, Gommerman JL, Gingras AC. Persistence of serum and saliva antibody responses to SARS-CoV-2 spike antigens in COVID-19 patients. Sci Immunol. 2020 Oct 8;5(52):eabe5511.

Sept 2020

  1. Berg MD, Brandl CJ. Transfer RNAs: diversity in form and function. RNA Biol. 2020 Sep 9:1-24. 
  2. Shirley BC, Knoll JHM, Moquet J, Ainsbury E, Duy PN, Norton F, Wilkins RC, Rogan PKEstimating partial body ionizing radiation exposure by automated cytogenetic biodosimetry. 
  3. Shirley BC, Knoll JHM, Moquet J, Ainsbury E, Duy PN, Norton F, Wilkins RC, Rogan PK.
  4. Zuanazzi D, Xiao Y, Siqueira WL. Evaluating protein binding specificity of titanium surfaces through mass spectrometry-based proteomics. Clin Oral Investig. 2020 Sep 1.
  5. Gitalis R, Bae JH, Preston M, Patel M, Liu Z, Sun C, Stewart C, Xiao Y, Siqueira WL, Glogauer M, Finer Y. Human neutrophils compromise the restoration-tooth interface. Acta Biomater. 2020 Sep 17:S1742-7061(20)30539-0.

Aug 2020

  1. Bourgeois R, Devillers R, Perrot N, Després AA, Boulanger MC, Mitchell PL, Guertin J, Couture P, Boffa MB, Scipione CA, Pibarot P, Koschinsky ML, Mathieu P, Arsenault BJ. Interaction of Autotaxin With Lipoprotein(a) in Patients With Calcific Aortic Valve Stenosis. JACC Basic Transl Sci. 2020 Aug 26;5(9):888-897.
  2. Lackie RE, Marques-Lopes J, Ostapchenko VG, Good S, Choy WY, van Oosten-Hawle P, Pasternak SH, Prado VF, Prado MAM. Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2020 Aug 21;8(1):143. 
  3. Slattery SS, Wang H, Giguere DJ, Kocsis C, Urquhart BL, Karas BJ, Edgell DR. Plasmid-based complementation of large deletions in Phaeodactylum tricornutum biosynthetic genes generated by Cas9 editing. Sci Rep. 2020 Aug 17;10(1):13879. 
  4. Kakadia JH, Jain BB, Biggar KK, Sutherland A, Nygard K, Li C, Nathanielsz PW, Jansson T, Gupta MB. Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient restricted baboons and may be a mechanism underlying IUGR. Am J Physiol Endocrinol Metab. 2020 Aug 3.
  5. Awamleh Z, Han VKM. Potential pathophysiological role of microRNA 193b-5p in human placentae from pregnancies complicated by preeclampsia and intrauterine growth restriction. Mol Biol Rep. 2020 Aug 16.
  6. Zheng KH, Kaiser Y, van Olden CC, Santos RD, Dasseux JL, Genest J, Gaudet D, Westerink J, Keyserling C, Verberne HJ, Leitersdorf E, Hegele RA, Descamps OS, Hopkins P, Nederveen AJ, Stroes ESG. No benefit of HDL mimetic CER-001 on carotid atherosclerosis in patients with genetically determined very low HDL levels. Atherosclerosis. 2020 Aug 29;311:13-19. 
  7. Dilliott AA, Wang J, Brown E, Singh G, Shkrum MJ, Clin M, Rupar CA, Hegele RA, Siu VM. A novel homozygous variant in REN in a family presenting with classic features of disorders involving the renin-angiotensin pathway, without renal tubular dysgenesis. Am J Med Genet A. 2020 Oct;182(10):2284-2290.
  8. Fraser DD, Cepinskas G, Patterson EK, Slessarev M, Martin C, Daley M, Patel MA, Miller MR, O'Gorman DB, Gill SE, Pare G, Prassas I, Diamandis E. Novel Outcome Biomarkers Identified With Targeted Proteomic Analyses of Plasma From Critically Ill Coronavirus Disease 2019 Patients. Crit Care Explor. 2020 Aug 24;2(9):e0189. 
  9. Fraser DD, Patterson EK, Slessarev M, Gill SE, Martin C, Daley M, Miller MR, Patel MA, Dos Santos CC, Bosma KJ, O'Gorman DB, Cepinskas G. Endothelial Injury and Glycocalyx Degradation in Critically Ill Coronavirus Disease 2019 Patients: Implications for Microvascular Platelet Aggregation. Crit Care Explor. 2020 Aug 24;2(9):e0194. 
  10. Lee JJ, Arpino JM, Yin H, Nong Z, Szpakowski A, Hashi AA, Chevalier J, O'Neil C, Pickering JG. Systematic Interrogation of Angiogenesis in the Ischemic Mouse Hind Limb: Vulnerabilities and Quality Assurance. Arterioscler Thromb Vasc Biol. 2020 Aug 13:ATVBAHA120315028. 
  11. Rogan PK, Mucaki EJ, Shirley BC. A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections [version 1; peer review: awaiting peer review]. F1000Research. 2020; 9:943. 
  12. Bringel M, Jorge PK, Francisco PA, Lowe C, Sabino-Silva R, Colombini-Ishikiriama BL, Machado MAAM, Siqueira WL. Salivary proteomic profile of dogs with and without dental calculus. BMC Vet Res. 2020 Aug 19;16(1):298. 

July 2020

  1. Prasad M, Balci TB, Prasad C, Andrews JD, Lee R, Jurkiewicz MT, Napier MP, Colaiacovo S, Guillen Sacoto MJ, Karp N. BCL11B-related disorder in two canadian children: Expanding the clinical phenotype. Eur J Med Genet. 2020 Jul 10:104007.
  2. Gonen A, Yang X, Yeang C, Alekseeva E, Koschinsky M, Witztum JL, Boffa MB, Tsimikas S. Generation and characterization of LPA-KIV9, a murine monoclonal antibody binding a single site on apolipoprotein(a). J Lipid Res. 2020 Jul 8:jlr.RA120000830
  3. Rajaram A, Yip LCM, Milej D, Suwalski M, Kewin M, Lo M, Carson JJL, Han V, Bhattacharya S, Diop M, de Ribaupierre S, St Lawrence K. Perfusion and Metabolic Neuromonitoring during Ventricular Taps in Infants with Post-Hemorrhagic Ventricular Dilatation. Brain Sci. 2020 Jul 15;10(7):E452.
  4. Feldman RD, Hegele RA. Primary aldosteronism in hypertension: more than a factoid. Can J Cardiol. 2020 Jul 3:S0828-282X(20)30585-7.
  5. Dron JS, Hegele RA. Genetics of Hypertriglyceridemia. Front Endocrinol (Lausanne). 2020 Jul 24;11:455.
  6. Hegele RA, Dron JS. 2019 George Lyman Duff Memorial Lecture: Three Decades of Examining DNA in Patients With Dyslipidemia. Arterioscler Thromb Vasc Biol. 2020 Jul 30:ATVBAHA120313065. 
  7. Mohebi R, Chen Q, Hegele RA, Rosenson RS. Failure of cosegregation between a rare STAP1 missense variant and hypercholesterolemia. J Clin Lipidol. 2020 Jul 24:S1933-2874(20)30220-8. 
  8. Hussain I, Jin RR, Baum HBA, Greenfield JR, Devery S, Xing C, Hegele RA, Carranza-Leon BG, Linton MF, Vuitch F, Wu KHC, Precioso DR, Oshima J, Agarwal AK, Garg A. Multisystem Progeroid Syndrome With Lipodystrophy, Cardiomyopathy, and Nephropathy Due to an LMNA p.R349W Variant. J Endocr Soc. 2020 Jul 27;4(10):bvaa104.
  9. Zhao X, Chen D, Szabla R, Zheng M, Li G, Du P, Zheng S, Li X, Song C, Li R, Guo JT, Junop M, Zeng H, Lin H. Broad and differential animal ACE2 receptor usage by SARS-CoV-2. J Virol. 2020 Jul 13:JVI.00940-20. 
  10. Aliyari E, Konermann L. Formation of Gaseous Proteins via the Ion Evaporation Model (IEM) in Electrospray Mass Spectrometry. Anal Chem. 2020 Jul 1.
  11. Ming L, Zou Y, Zhao Y, Zhang L, He N, Chen Z, Li SS, Li L. MMS2plot: An R Package for Visualizing Multiple MS/MS Spectra for Groups of Modified and Non-Modified Peptides. Proteomics. 2020 Jul 8:e2000061.
  12. Biggar KK, Charih F, Liu H, Ruiz-Blanco YB, Stalker L, Chopra A, Connolly J, Adhikary H, Frensemier K, Hoekstra M, Galka M, Fang Q, Wynder C, Stanford WL, Green JR, Li SS. Proteome-wide Prediction of Lysine Methylation Leads to Identification of H2BK43 Methylation and Outlines the Potential Methyllysine Proteome. Cell Reports. 2020 Jul 14;32, 107896. 
  13. Fraser DD, Cepinskas G, Slessarev M, Martin C, Daley M, Miller MR, O'Gorman DB, Gill SE, Patterson EK, Dos Santos CC. Inflammation Profiling of Critically Ill Coronavirus Disease 2019 Patients. Version 2. Crit Care Explor. 2020 Jun 22;2(6):e0144.
  14. Rao S, Pitel B, Wagner AH, Boca SM, McCoy M, King I, Gupta S, Park BH, Warner JL, Chen J, Rogan PK, Chakravarty D, Griffith M, Griffith OL, Madhavan S. Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices. JCO Clin Cancer Inform. 2020 Jul;4:602-613.

June 2020

  1. Aref-Eshghi E, McGee JD, Pedro VP, Kerkhof J, Stuart A, Ainsworth PJ, Lin H, Volodarsky M, McLachlin CM, Sadikovic B. Genetic and epigenetic profiling of BRCA1/2 in ovarian tumors reveals additive diagnostic yield and evidence of a genomic BRCA1/2 DNA methylation signature. J Hum Genet. 2020 Jun 1.
  2. Tajoddin NN, Konermann L. Analysis of Temperature-Dependent H/D Exchange Mass Spectrometry Experiments. Anal Chem. 2020 Jun 19.
  3. Youssef A, Clark JR, Koschinsky ML, Boffa MB Lipoprotein(a): Expanding Our Knowledge of Aortic Valve Narrowing. Trends Cardiovasc Med. 2020 Jun 7:S1050-1738(20)30080-3. 
  4. Abu Shehab M, Biggar K, Kakadia JH, Dhruv M, Jain B, Nandi P, Nygard K, Jansson T, Gupta MB. Inhibition of decidual IGF-1 signaling in response to hypoxia and leucine deprivation is mediated by mTOR and AAR pathways and increased IGFBP-1 phosphorylation. Mol Cell Endocrinol. 2020 Jun 2;512:110865.
  5. Khera AV, Hegele RA. What Is Familial Hypercholesterolemia, and Why Does It Matter? Circulation. 2020 June 2;141(22):1760‐1763.
  6. Lazarte J, Hegele RA. Can genetic testing help in the management of dyslipidaemias? Curr Opin Lipidol. 2020 Jun 8.
  7. Dron JS, Dilliott AA, Lawson A, McIntyre AD, Davis BD, Wang J, Cao H, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia. Arterioscler Thromb Vasc Biol. 2020 Jun 25:ATVBAHA120314168.
  8. Ramirez J, Dilliott AA, Binns MA, Breen DP, Evans EC, Beaton D, McLaughlin PM, Kwan D, Holmes MF, Ozzoude M, Scott CJM, Strother SC, Symons S, Swartz RH, Grimes D, Jog M, Masellis M, Black SE, Joutel A, Marras C, Rogaeva E, Hegele RA, Lang AE; Ontario Neurodegenerative Disease Research Initiative Investigators. Parkinson's Disease, NOTCH3 Genetic Variants, and White Matter Hyperintensities. Mov Disord. 2020 Jun 23.
  9. Varga A, Hegele RA. Triglyceride-rich particles: new actors in valvular aortic stenosis. Eur Heart J. 2020 Jun 21;41(24):2300-2303.
  10. Lazarte J, Berberich AJ, Wang J, Hegele RA. A cautionary tale: Is this APOB whole-gene duplication actually pathogenic? J Clin Lipidol. 2020 Jun 15:S1933-2874(20)30207-5.
  11. Berberich AJ, Wang J, Cao H, McIntyre AD, Spaic T, Miller DB, Stock S, Huot C, Stein R, Knoll J, Yang P, Robinson JF, Hegele RA. Simplifying Detection of Copy-Number Variations in Maturity-Onset Diabetes of the Young. Can J Diabetes. 2020 Jun 8:S1499-2671(20)30172-6.
  12. Veras MA, Lim YJ, Kuljanin M, Lajoie GA, Urquhart BL, Séguin CA. Protocol for parallel proteomic and metabolomic analysis of mouse intervertebral disc tissues. JOR Spine. 2020 Jun 10;3(3):e1099.
  13. Chevalier J, Yin H, Arpino JM, O'Neil C, Nong Z, Gilmore KJ, Lee JJ, Prescott E, Hewak M, Rice CL, Dubois L, Power AH, Hamilton DW, Pickering JG. Obstruction of Small Arterioles in Patients with Critical Limb Ischemia due to Partial Endothelial-to-Mesenchymal Transition. iScience. 2020 Jun 26;23(6):101251.
  14. Saeed SG, Bain J, Khoo E, Siqueira WL. COVID-19: Finding silver linings for dental education. J Dent Educ. 2020 Jun 2.
  15. Verma S, Chanchlani R, Siu VM, Filler G. Transient hyponatremia of prematurity caused by mild Bartter syndrome type II: a case report. BMC Pediatr. 2020 Jun 26;20(1):311.
  16. Hassan HM, Isovic M, Underhill MT, Torchia J. TDG is a novel tumor suppressor of liver malignancies. Mol Cell Oncol. 2020 Jun 17;7(4):1768819.
  17. Kelman MJ, Renaud JB, Seifert KA, Mack J, Yeung KK, Sumarah MW. Chemotaxonomic Profiling of Canadian Alternaria Populations Using High-Resolution Mass Spectrometry. Metabolites. 2020 Jun 9;10(6):E238. 

May 2020

  1. Zhu Y, Berg MD, Yang P, Loll-Krippleber R, Brown GW, Brandl CJ. Mistranslating tRNA identifies a deleterious S213P mutation in the Saccharomyces cerevisiae eco1-1 allele. Biochem Cell Biol. 2020 May 30.
  2. Singha B, Laski J, Ramos Valdés Y, Liu E, DiMattia GE, Shepherd TG. Inhibiting ULK1 kinase decreases autophagy and cell viability in high-grade serous ovarian cancer spheroids. Am J Cancer Res. 2020 May 1;10(5):1384-1399.
  3. Powell JT, Hegele RA. From Laundry List to Rating Scheme: Selection of the Best Scientific Method. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1018-1019.
  4. Brown EE, Sturm AC, Cuchel M, Braun LT, Duell PB, Underberg JA, Jacobson TA, Hegele RA. Genetic testing in dyslipidemia: A scientific statement from the National Lipid Association. J Clin Lipidol. 2020 May 7:S1933-2874(20)30081-7. 
  5. Castilla-Vallmanya L, Selmer KK, Dimartino C, Rabionet R, Blanco-Sánchez B, Yang S, Reijnders MRF, van Essen AJ, Oufadem M, Vigeland MD, Stadheim B, Houge G, Cox H, Kingston H, Clayton-Smith J, Innis JW, Iascone M, Cereda A, Gabbiadini S, Chung WK, Sanders V, Charrow J, Bryant E, Millichap J, Vitobello A, Thauvin C, Mau-Them FT, Faivre L, Lesca G, Labalme A, Rougeot C, Chatron N, Sanlaville D, Christensen KM, Kirby A, Lewandowski R, Gannaway R, Aly M, Lehman A, Clarke L, Graul-Neumann L, Zweier C, Lessel D, Lozic B, Aukrust I, Peretz R, Stratton R, Smol T, Dieux-Coëslier A, Meira J, Wohler E, Sobreira N, Beaver EM, Heeley J, Briere LC, High FA, Sweetser DA, Walker MA, Keegan CE, Jayakar P, Shinawi M, Kerstjens-Frederikse WS, Earl DL, Siu VM, Reesor E, Yao T, Hegele RA, Vaske OM, Rego S; Undiagnosed Diseases Network, Care4Rare Canada Consortium, Shapiro KA, Wong B, Gambello MJ, McDonald M, Karlowicz D, Colombo R, Serretti A, Pais L, O'Donnell-Luria A, Wray A, Sadedin S, Chong B, Tan TY, Christodoulou J, White SM, Slavotinek A, Barbouth D, Morel Swols D, Parisot M, Bole-Feysot C, Nitschké P, Pingault V, Munnich A, Cho MT, Cormier-Daire V, Balcells S, Lyonnet S, Grinberg D, Amiel J, Urreizti R, Gordon CT. Phenotypic spectrum and transcriptomic profile associated with germline variants in TRAF7. Genet Med. 2020 May 7.
  6. Rabi DM, McBrien KA, Sapir-Pichhadze R, et al. (including Hegele RA) Hypertension Canada's 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children. Can J Cardiol. 2020;36(5):596‐624.
  7. Lau P, Soubeyrand S, Hegele RA, Lagace TA, McPherson R. Molecular mechanism linking a novel PCSK9 copy number variant to severe hypercholesterolemia. Atherosclerosis. 2020 May 28;304:39-43.
  8. Yin V, Konermann L. Probing the Effects of Heterogeneous Oxidative Modifications on the Stability of Cytochrome c in Solution and in the Gas Phase. J Am Soc Mass Spectrom. 2020 May 13.
  9. Tarnopolsky MA, Kerkhof J, Stuart A, Bujak A, Nilsson MI, Hettinga B, May L, Rupar CA, Sadikovic B. Bone
    marrow-derived mitochondrial DNA has limited capacity for inter-tissue transfer in vivo. FASEB J. 2020 May 22.
  10. Rodrigues RPCB, de Andrade Vieira W, Siqueira WL, Blumenberg C, de Macedo Bernardino Í, Cardoso SV, Flores-Mir C, Paranhos LR. Saliva as an alternative to blood in the determination of uremic state in adult patients with chronic kidney disease: a systematic review and meta-analysis. Clin Oral Investig. 2020 May 23.
  11. Hauser-Kawaguchi A, Tolg C, Peart T, Milne M, Turley EA, Luyt LG. Corrigendum to "A truncated RHAMM protein for discovering novel therapeutic peptides" [Bioorg. Med. Chem. 26 (2018) 5194-5203] Bioorg Med Chem. 2020 May 16;115543. 
  12. Turley EA. HIPPO and Hyaluronan: Partners in Tumor Resistance? Bioessays. 2020 May 24:e2000090.

Apr 2020

  1. Hegele RA, Knowles JW, Horton JD. Delisting STAP1: The Rise and Fall of a Putative Hypercholesterolemia Gene. Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):847-849.
  2. Heidari A, Ghorbani-Choghamarani A, Hajjami M, Hudson RHE. Fluorescent Biaryl Uracils with C5-Dihydro- and Quinazolinone Heterocyclic Appendages in PNA. Molecules. 2020 Apr 24;25(8). pii: E1995.
  3. Sever AIM, Konermann L. Gas Phase Protein Folding Triggered by Proton Stripping Generates Inside-Out Structures: A Molecular Dynamics Simulation Study. J Phys Chem B. 2020 Apr 14.
  4. Sherman SE, Kuljanin M, Cooper TT, Lajoie G, Hess DA. Purification and functional characterization of CD34-expressing cell subsets following ex vivo expansion of umbilical cord blood-derived endothelial colony forming cells. Stem Cells Dev. 2020 Apr 25.
  5. Balasuriya N, Davey NE, Johnson JL, Liu H, Biggar KK, Cantley LC, Li SS, O'Donoghue P. Phosphorylation-dependent substrate selectivity of protein kinase B (AKT1). J Biol Chem. 2020 Apr 29. pii: jbc.RA119.012425.
  6. Rogan PK, Mucaki EJ, Lu R, Shirley BC, Waller E, Knoll JHM. Meeting radiation dosimetry capacity requirements of population-scale exposures by geostatistical sampling. PLoS One. 2020 Apr 24;15(4):e0232008.
  7. Hassan HM, Isovic M, Kolendowski B, Bauer-Maison N, Onabote O, Cecchini M, Haig A, Maleki Vareki S, Underhill TM, Torchia J. Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma. Cell Rep. 2020 Apr 7;31(1):107475.

Mar 2020

  1. Berberich AJ, Hegele RA. Research digest: next-generation lipoprotein therapeutics. Lancet Diabetes Endocrinol. 2020 Mar;8(3):190.
  2. Ueda M, Wolska A, Burke FM, Escobar M, Walters L, Lalic D, Hegele RA, Remaley AT, Rader DJ, Dunbar RL. Experimental Therapeutics for Challenging Clinical Care of a Patient with an Extremely Rare Homozygous APOC2 Mutation. Case Rep Endocrinol. 2020 Mar 27;2020:1865489.
  3. Lazarte J, Hegele RA. Pediatric Dyslipidemia-Beyond Familial Hypercholesterolemia. Can J Cardiol. 2020 Mar 23:S0828-282X(20)30275-0.
  4. Schnitzler J, Hoogeveen RM, Ali L, Prange KH, Waissi F, Van Weeghel MV, Bachmann JC, Versloot M, Borrelli MJ, Yeang C, de Kleijn D, Houtkooper RH, Koschinsky M, de Winther MP, Groen AK, Witztum JL, Tsimikas S, Stroes ES, Kroon J. Atherogenic Lipoprotein(A) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation. Circ Res. 2020 Mar 12.
  5. Mucaki EJ, Shirley BC, Rogan PK. Expression Changes Confirm Genomic Variants Predicted to Result in Allele-Specific, Alternative mRNA Splicing. Front Genet. 2020 Mar 5;11:109.
  6. Melo IS, Candeia-Medeiros N, Ferro JNS, Cavalcante-Araújo PM, Oliveira TL, Santos CEA, Cardoso-Sousa L, Aguiar EMG, Wutke Oliveira S, Castro OW, Alves-Balvedi RP, Rodrigues LP, Hickmann JM, Alves DA, Santos IA, Jardim ACG, Siqueira WL, Pipi ARF, Goulart LR, Barreto EO, Sabino-Silva R. Restoration of Cyclo-Gly-Pro-induced salivary hyposecretion and submandibular composition bynaloxone in mice. PLoS One. 2020 Mar 10;15(3):e0229761.
  7. Caixeta DC, Aguiar EMG, Cardoso-Sousa L, Coelho LMD, Oliveira SW, Espindola FS, Raniero L, Crosara KTB, Baker MJ, Siqueira WL, Sabino-Silva R. Salivary molecular spectroscopy: A sustainable, rapid and non-invasive monitoring tool for diabetes mellitus during insulin treatment. PLoS One. 2020 Mar 17;15(3):e0223461.
  8. Tolg C, Liu M, Cousteils K, Telmer P, Alam K, Ma J, Medina L, McCarthy JB, Morris VL, Turley EA. Cell-specific expression of the transcriptional regulator RHAMM provides a timing mechanism that controls appropriate wound re-epithelialization. J Biol Chem. 2020 Mar 12. pii: jbc.RA119.010002. 

Feb 2020

  1. Aref-Eshghi E, Kerkhof J, Pedro VP; Groupe DI France, Barat-Houari M, Ruiz-Pallares N, Andrau JC, Lacombe D, Van-Gils J, Fergelot P, Dubourg C, Cormier-Daire V, Rondeau S, Lecoquierre F, Saugier-Veber P, Nicolas G, Lesca G, Chatron N, Sanlaville D, Vitobello A, Faivre L, Thauvin-Robinet C, Laumonnier F, Raynaud M, Alders M, Mannens M, Henneman P, Hennekam RC, Velasco G, Francastel C, Ulveling D, Ciolfi A, Pizzi S, Tartaglia M, Heide S, Héron D, Mignot C, Keren B, Whalen S, Afenjar A, Bienvenu T, Campeau PM, Rousseau J, Levy MA, Brick L, Kozenko M, Balci TB, Siu VM, Stuart A, Kadour M, Masters J, Takano K, Kleefstra T, de Leeuw N, Field M, Shaw M, Gecz J, Ainsworth PJ, Lin H, Rodenhiser DI, Friez MJ, Tedder M, Lee JA, DuPont BR, Stevenson RE, Skinner SA, Schwartz CE, Genevieve D, Sadikovic B. Evaluation of DNA Methylation Episignatures for Diagnosis and Phenotype Correlations in 42 Mendelian Neurodevelopmental Disorders. Am J Hum Genet. 2020 Feb 26. pii: S0002-9297(20)30019-7.
  2. Hooper AJ, Hegele RA, Burnett JR. Tangier disease: update for 2020. Curr Opin Lipidol. 2020 Feb 4.
  3. Borén J, Chapman MJ, Krauss RM, Packard CJ, Bentzon JF, Binder CJ, Daemen MJ, Demer LL, Hegele RA, Nicholls SJ, Nordestgaard BG, Watts GF, Bruckert E, Fazio S, Ference BA, Graham I, Horton JD, Landmesser U, Laufs U, Masana L, Pasterkamp G, Raal FJ, Ray KK, Schunkert H, Taskinen MR, van de Sluis B, Wiklund O, Tokgozoglu L, Catapano AL, Ginsberg HN. Low-density lipoproteins cause atherosclerotic cardiovascular disease: pathophysiological, genetic, and therapeutic insights: a consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2020 Feb 13. pii: ehz962.
  4. Dron JS, Wang J, McIntyre AD, Iacocca MA, Robinson JF, Ban MR, Cao H, Hegele RA. Six years' experience with LipidSeq: clinical and research learnings from a hybrid, targeted sequencing panel for dyslipidemias. BMC Med Genomics. 2020 Feb 10;13(1):23.
  5. Lazarte J, Hegele RA. Regression of Xanthelasmas With Statin Treatment in a Normolipidemic Patient. Ann Intern Med. 2020 Feb 18.
  6. Duez Q, Metwally H, Hoyas S, Lemaur V, Cornil J, De Winter J, Konermann L, Gerbaux P. Effects of electrospray mechanisms and structural relaxation on polylactide ion conformations in the gas phase: insights from ion mobility spectrometry and molecular dynamics simulations. Phys Chem Chem Phys. 2020 Feb 10.
  7. Mucaki EJ, Shirley BC, Rogan PK. Expression Changes Confirm Genomic Variants Predicted to Result in Allele-Specific, Alternative mRNA Splicing. Front. Genet. 2020; 11:109.
  8. Baudier J, Deloulme JC, Shaw GS. The Zn(2+) and Ca(2+) -binding S100B and S100A1 proteins: beyond the myths. Biol Rev Camb Philos Soc. 2020 Feb 6.
  9. Cook BW, Lacoursiere RE, Shaw GS. Recruitment of Ubiquitin within an E2 Chain Elongation Complex. Biophys J. 2020 Feb 15. pii: S0006-3495(20)30133-8.
  10. Sabino-Silva R, Jardim ACG, Siqueira WL. Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis. Clin Oral Investig. 2020 Feb 20.

Jan 2020

  1. Llaurado Fernandez M, Dawson A, Kim H, Lam N, Russell H, Bruce M, Bittner M, Hoenisch J, Scott SA, Talhouk A, Chiu D, Provencher D, Nourmoussavi M, DiMattia G, Lee CH, Gilks CB, Köbel M, Carey MS. Hormone receptor expression and outcomes in low-grade serous ovarian carcinoma. Gynecol Oncol. 2020 Jan 14. pii: S0090-8258(19)31680-4.
  2. Yang S, Reid G, Challis JRG, Gloor GB, Asztalos E, Money D, Seney S, Bocking AD. Effect of Oral Probiotic Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 on the Vaginal Microbiota, Cytokines and Chemokines in Pregnant Women. Nutrients. 2020 Jan 30;12(2). pii: E368.
  3. Awamleh Z, Han VKM. Identification of miR-210-5p in human placentae from pregnancies complicated by preeclampsia and intrauterine growth restriction, and  its potential role in the pregnancy complications. Pregnancy Hypertens. 2020 Jan 14;19:159-168.
  4. Lu HS, Schmidt AM, Hegele RA, Mackman N, Rader DJ, Weber C, Daugherty A. Annual Report on Sex in Preclinical Studies: Arteriosclerosis, Thrombosis, and Vascular Biology Publications in 2018. Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):e1-e9.
  5. Berberich AJ, Hegele RA. LDL cholesterol: lower, faster, younger? Lancet Diabetes Endocrinol. 2020 Jan;8(1):5-7.
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