Research Positions Available

two students looking at DNA gel

 

Undergraduate Students - Summer Research in Biochemistry Labs

If you are interested in doing research in the Dept. of Biochemistry during the summer, consider the following options:

Contact Biochemistry faculty whose research interests you to see if they will take you into their labs.

More Information - Biochemistry Faculty Research

Undergraduate Students - Volunteer Positions

Are you interested in volunteering in a Biochemistry research lab? Contact one of the following faculty:

Also check for posted opportunities on Western Connect.

More Information - Biochemistry Faculty Research

Undergraduate Students - Western's Work Study Program

  • Students can work part-time on campus in jobs that accommodate their studies (such as working in a Biochemistry research lab)
  • Applicants must demonstrate genuine financial need
  • Offered for fall/winter term and summer term

More Information - Western's Work Study Program

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Dean's Undergraduate Research Opportunities Program (DUROP)

This program provides science undergraduate students with hands-on experience working in a research lab during the summer in the Schulich School of Medicine & Dentistry.

More Information - DUROP

More Information - Biochemistry Faculty Research

Graduate Students

See the webpage Graduate Positions Available.

Postdoctoral Scholars

The faculty listed below are actively looking for postdoctoral scholars. You are also encouraged to contact other research faculty in the Biochemistry Dept. for potential postdoctoral positions.

More Information - Biochemistry Faculty Research

Dr. Madhulika Gupta

Position 1

JOB DESCRIPTION
A postdoctoral fellowship or research associate position is immediately available in the Department of Pediatrics and Biochemistry/Children's Health Research Institute, University of Western Ontario, London, ON, Canada with Dr. Madhulika B Gupta. The research program focuses on exploring cellular and molecular mechanisms of regulation of fetal and maternal insulin-like growth factor binding protein-1 phosphorylation to investigate the functional role of this IGF binding protein in determining fetal growth and long-term health. A wide variety of model systems including cultured cell lines and primary cells, human placental tissue, maternal and cord plasma and amniotic fluid are utilized. Translational approaches, ranging from biochemical, molecular, proteomics, gene targeting (siRNA silencing) ELISAs, and immunohistochemistry are involved to better understand the pathophysiology of human fetal growth restriction.

Current project includes the studies on establishing the mechanistic role of MTOR, AAR and other key nutrient sensing signaling pathways in regulating decidual IGFBP-1 secretion and phosphorylation in fetal growth restriction. The goal is to identify a novel molecular mechanism contributing to human fetal growth restriction.

DESIRED SKILLS AND EXPERIENCE
A PhD in Biochemistry, or a related scientific field is required. To be successful in this position, the candidate must be highly motivated and able to work independently to design and execute experiments, possess a high level of initiative, and must also be able to work on a related projects simultaneously by prioritizing work as required. S/he must be capable of working independently in a team environment. Candidates with excellent organizational skills and communication skills (written and oral) are encouraged to apply. The candidate will be expected to publish and present their work in both internal and external events.

Experience in mammalian cell culture is highly desired. Experience particularly with primary cell culture is preferred.

For more information, please contact Madhulika Gupta by email.

Some relevant publications:
1) Singal SS et al 2017 AM J Pathology (Cellular and Mol Biol of disease) (In Press). DOI: http://dx.doi.org/10.1016/j.ajpath.2017.09.009
2) Shehab AM et al 2017 Mol Cellular Endocrinol 452: 1-14.
3) Damerill I et al 2016 Mol Endocrinol 30(2): 201-16.
4) Malkani N et al 2016 Mol Cellular Endocrinol 425: 48-60.
5) Malkani N et al 2015 Mol Cellular Endocrinol 412: 182–195.
6) Shehab MA et al 2014 Endocrinology 55:1327-39.
7) Seferovic MD & Gupta M.B 2016 Disease Markers: 2016;2016:7124186. doi: 10.1155/2016/7124186. Epub 2016 Jan 19.

Position 2

JOB DESCRIPTION
One postdoctoral fellowship (full time) is immediately available in the Department of Pediatrics and Biochemistry and, Children's Health Research Institute, University of Western Ontario with Dr. Madhulika B Gupta (Duration of Contract: 12 months, with possibility of renewal on an annual basis). The position is open until filled.

The research program focuses on exploring cellular and molecular mechanisms of regulation of fetal and maternal Insulin- like growth factor binding protein-1 phosphorylation to investigate the functional role of this IGF binding protein in determining fetal growth and long-term health. A wide variety of model systems including cultured cell lines and primary cells, placental tissue, maternal and cord plasma and amniotic fluid are utilized. Translational approaches, ranging from biochemical, molecular, proteomics, gene targeting and immunohistochemistry are involved to better understand the pathophysiology of human fetal growth restriction (FGR).

QUALIFICATIONS 
  • Highly motivated candidate holding a PhD degree and with documented training and experience in biochemistry, molecular/cell biology and/or proteomics;
  • Experience working with cell culture and particularly with primary cell culture;
  • Excellent organizational, analytical and problem-solving skills;
  • Excellent oral and written communication skills;
  • Ability to work effectively both independently and as part of a team.

 

For more information, please contact Madhulika Gupta by email.

RELEVANT PUBLICATIONS
1) Kakadia JH, Jain B, Biggar K, Sutherland A, Nygard K, Li C, Nathanielsz PW, Jansson T, and Gupta MB (2020). Hyperphosphorylation of fetal liver IGFBP-1 precedes slowing of fetal growth in nutrient restricted baboon and may be a mechanism underlying IUGR. American Journal of Physiology: Endocrinology and Metabolism, 313: E614-E628. doi.org/10.1152/ajpendo.00220.2020

2) Gupta MB, Abu Shehab M, Nygard K, Biggar K, Singal SS, Santoro N, Powell TL and Jansson T (2019). IUGR is associated with marked hyperphosphorylation of decidual and maternal plasma IGFBP-1. Journal of Clinical Endocrinology & Metabolism. 2019 Feb 1;104(2):408-422. doi: 10.1210/jc.2018-00820

3) Gupta MB, Jansson T (2019). Novel roles of mechanistic target of rapamycin signaling in regulating fetal growth. Biol Reprod. 2019 Apr 1;100(4):872-884. doi: 10.1093/biolre/ioy249

Dr. Shawn Li

Multiple post-doctoral positions are now available in Dr. Shawn Li's laboratory in the Dept. of Biochemistry, Schulich School of Medicine & Dentistry, Western University. Interested candidates should be highly motivated team players who have a strong desire to work in a collaborative environment equipped with world-class research facilities. You will be involved in a research project aimed at deciphering signaling pathways and protein-interaction networks relevant to cancer metastasis using a variety of methods, including both conventional and proteomics approaches.

Requirements include a PhD degree or equivalent in Biochemistry, Molecular Biology, Bio-organic Chemistry, Cell Biology, or Immunology. Candidates with prior publications, relevant research experience, and excellent verbal/written English communication skills will be considered. Salary is highly competitive and commensurate with experience.

Applicants should send a CV and names of three references to Dr. Shawn Li by email or by fax at 519.661.3175.

For more information, visit the lab website of Dr. Shawn Li.

Dr. Hong Ling

A postdoctoral position in structural biology is available at Dr. Hong Ling's Laboratory in the Department of Biochemistry, Western University, London, Ontario, Canada. The research is focused on translesion DNA replication and regulation of DNA damage response. The current projects are built on our success in cloning, expression and purification of the key proteins in the biological systems. Combined approaches in molecular biology, biophysics and X-ray crystallography are employed in the structure-function studies of the key proteins. The laboratory is fully equipped for molecular biology, biochemistry, biophysics and X-ray crystallography analyses. The position requires a Ph.D. degree with experience in molecular cloning, protein purification, crystallization and structure determination with prior publications.

Western University is located in London, Ontario. London is a comfortable city (population: 350,000) with a reasonable cost of living.  It is close to major North American cities, such as Toronto and Detroit.

Please send CV and the names of three references to Dr. Hong Ling by email. For more information, visit the lab website of Dr. Ling.

Dr. Geoffrey Pickering

A postdoctoral position is available in Dr. Pickering's lab at Western University. Contact information is as follows:

Robarts Research Institute 4245D
Western University
London, ON, Canada
t. 519-685-8500 ext. 55066
email   

Dr. Gary Shaw

A postdoctoral position is available in Dr. Gary Shaw’s laboratory in the Department of Biochemistry at Western University (London, Canada). The successful applicant will be involved in an exciting and world-class research program to examine the mechanisms of ubiquitination involved in neurodegenerative diseases, including three-dimensional structure and protein interactions. Candidates should be highly motivated and strong team players. Experience in methods such as molecular biology, protein purification, NMR spectroscopy, X-ray crystallography and molecular modelling would be an asset. Further information on research in the lab can be found on the Shaw lab website. The starting salary is highly competitive and will be based on qualifications.

The preferred qualifications include a recent Ph.D. in Biochemistry, Chemistry, or a related field with a competitive publication record. Applicants are expected to have strong organizational skills and excellent written and verbal skills in English.

Western University is in London, Ontario, and is Canada’s 11th largest city. Located in Southwestern Ontario, London offers many of the features and health-care advantages of a larger city but is far more affordable than most Canadian and American cities. For further information, please see Western's Visitor Information about London.

Applications should send a CV and contact information for references to Dr. Gary Shaw by email. The starting date is flexible but is preferably within the next 6 months.