Outcome of Epilepsy Surgery in Patients with Medically Resistant Epilepsy

The purpose of this study is to identify the profile of patients with medically resistant epilepsy with better outcomes after surgery. This is a genetic sub-study that will try and correlate surgical outcome and genetic testing results. We plan to include a retrospective cohort of patients who had undergone surgery but are no longer being followed at the hospital (dating back to 1999). All data will be entered into REDCap. A Research Coordinator will obtain written consent from patients in the clinic, which will take about 5-10 minutes. This study involves collecting data from patient medical charts, with no additional tasks.
Inclusion criteria:
- Patients who underwent or will undergo any type of lobectomy, lesionectomies, hemispherotomies, hemispherectomies, neuromodulation implantation, minimally invasive surgery, and multiple subpial transections at LHSC.
- The patient's age at epilepsy surgery was between one month to 80 years old.
Exclusion criteria:
- Patients who underwent neurosurgical procedures for reasons other than epilepsy.
- Patients with follow-up less than 1 year.
- Patients who were younger than one month or older than 80 years.
- Failure to provide consent by patient or patient's substitute decision maker (for prospective cohort).
Principal Investigator: Dr. Ana Suller Marti
Suzan Brown (Research Coordinator) and Mariam Elnazali (Research Assistant), will obtain written consent from patients in the clinic.