2019 Paterson Lecture

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The 2019 Paterson Lecture was held on Thursday, November 14, 2019.  We were fortunate to have Dr. Jeffrey Ravetch, Theresa and Eugene Lang Professor at the Rockefeller University and Head of the Leonard Wagner Laboratory of Molecular Genetics and Immunology, deliver the 2019 Lecture.  Dr. Ravetch is a pioneering scientist and one of the most highly cited immunology researchers in the world.  He has received numerous awards for his outstanding research. These include a Gairdner International Award in 2012, a Wolf Prize in Medicine in 2015, a Ross Prize in Molecular Medicine in 2017, and a Robert Koch Award in 2018.

Dr. Ravetch synthesized and presented his group’s decade-long effort to understand how antibodies mediate their diverse effector functions.  He explained how the degree and pattern of sialylation of the invariant stem (Fc) region of antibodies can switch their pro- and anti-inflammatory properties.  He also shared his thoughts and his group’s work on the redesign of antibodies to enhance their therapeutic capacity for the treatment of infectious, neoplastic and inflammatory diseases.

Special thank you to Angela DeCandido, Nan Meng, Tracey Koning, Kathilyn Allewell, Cheryl Campbell and Susan Underhill for their hard work in organizing the Paterson Lecture.

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