Saman Maleki
Assistant Professor,
Departments of Oncology, Pathology and Laboratory Medicine, and Medical Biophysics
MSc University of Isfahan (Iran)
PhD Western University
Office: CRLP, LRCP, A4-102
Phone: (519) 685-8500 Ext.55769
E-mail: smaleki2@uwo.ca
Visit: The Maleki Lab Website
Clinical Activities
Keywords: cancer, immuno-oncology, cancer immunotherapy, microbiome, translational research, immune-related adverse events, melanoma, renal cell carcinoma, lung cancer
Description of Research Activities: Phase I clinical trials in Immuno-Oncology and Microbiome Modifications via Fecal Microbiota Transplantation.
Current Clinical Trial: NCT03772899 (Melanoma), NCT04163289 (Renal Cell Carcinoma)
Research Activities
Keywords: tumor immunology, neoantigen, T-cells, microbiome, fecal microbiota transplantation, neuroblastoma, breast cancer, colorectal cancer, pancreatic cancer, melanoma, head and neck cancer
Description of Research Activities: Dr. Maleki’s research is focused on understanding how to sensitize hard-to-treat cancers to immunotherapy with immune checkpoint inhibitors. In particular, inducing neoantigen formation in tumor cells by blocking their DNA repair pathways and studying the effect of changing the gut microbiome on anti-tumor immunity and immune-related toxicities.
Publications on PubMed: https://bit.ly/2QuiQAX
Research Opportunities
We are always looking for graduate students, post-doctoral fellows, and residents who share our passion for translational research in Immuno-Oncology.
