About Us

The Singh lab's research interest centers on understanding the mechanisms that contribute to cardiovascular diseases, with the aim of identifying molecular targets for therapeutic advancement. We study endothelial cells extensively and are currently investigating the role of DNA damage & repair, autophagy and endothelial to mesenchymal transition (EndMT) in cardiovascular pathophysiology. We utilize in vitro (cell culture), in vivo (generation of tissue-specific knockdown mice), ex vivo and translational (clinical samples) approaches in our experiments. Our lab is dedicated to the novel findings about the essentials impacts on cardiophysiology from various pathological aspects at the cellular level.

We currently hold research grants from the Canadian Institutes of Health Research, and Heart and Stroke Foundation of Canada.