Juan Pablo Arab

Image of Dr. Juan Pablo Arab

Research Interests / Specializations

Gastroenterology, Hepatology, Transplant Hepatology, Clinical/Translational Research, Epidemiology in Alcohol-related Liver Disease and Metabolic dysfunction-associated Liver Disease, Liver Cancer, Cirrhosis


Dr. Arab is Associate Professor of Medicine at the Division of Gastroenterology, Department of Medicine, and the Department of Epidemiology and Biostatistics at Schulich School of Medicine, Western University, London, Ontario, Canada. Trained at the Pontificia Universidad Catolica, Chile and Mayo Clinic, Rochester, MN, USA.

Dr. Arab is a Gastroenterology and Hepatology specialist, Transplant Hepatologist, and Clinical Researcher with an interest in clinical/translational research and epidemiology in alcohol-related liver disease (ALD) and metabolic dysfunction-associated steatotic liver disease (MASLD). He has published more than 180 peer-reviewed papers, co-authored several book chapters, and delivered lectures on liver-related topics at national and international meetings. He has also participated in the generation of clinical practice guidelines for alcohol-related liver disease, metabolic dysfunction-associated steatotic liver disease, and hepatorenal syndrome and regularly serves as an expert reviewer of research grants and scientific research abstracts for multiple societies, funding agencies, and international peer-reviewed journals. He is also a Scientist at the Lawson Health Research Institute.

He is an Associate Editor for Hepatology (flagship American Association for the study of Liver Diseases [AASLD] journal). Additionally, he is spearheading international collaboration groups aiming to study alcohol-associated liver disease and metabolic dysfunction-associated steatotic liver disease (AH-LATIN, STELLA, and Global AlcHep BigData Network). Dr. Arab is a member of the AASLD Global Outreach and Engagement Committee. He is currently the Chair of the Special Interest Group on alcohol-associated liver disease of the AASLD. Additionally, he is the Chair of the Education & Scholarship Committee of the International Liver Transplantation Society (ILTS). 

Selected Publications

2009 Arab JP, Pizarro M, Solis N, Sun H, Thevananther S, Arrese M. Mild hypothermia does not affect liver regeneration after partial hepatectomy in mice. Liver Int. 2009 Mar;29(3):344-8.

2009 Ramírez C, Arab JP, Riquelme A, Arrese M. Nonalcoholic fatty liver: a relevant entity to the endocrinologist. Rev. chil. endocrinol. diabetes 2009; 2 (4): 235-240. (Article in Spanish)

2009 Arab JP, Ramírez C, Muñoz P, Pizarro M, Solís N, Riquelme A, Arrese M. Effects of Japanese herbal medicine inchin-ko-to on endotoxin-induced cholestasis in the rat. Ann Hepatol. 2009 Jul-Sep;8(3):228-33.

2010 Arab JP, Ramírez C, Arrese M. Early warning of Liver Disease in diabetics. Ann Hepatol. 2010 Jul-Sep, 9(3):307-309.

2010 Ramírez C, Arab JP, Eymin G. Pneumonia caused by Streptococcus pyogenes. Report of one case. Rev Med Chile 2010; Jul;138(7):847-51. (Article in Spanish)

2010 Arab JP, Pavez C, Soza A, Arrese M, Riquelme A. Mycoplasma pneumoniae cholestatic hepatitis without lung involvement. Case report and review of literature. Gastroenterol. latinoam 2010; Vol 21, Nº 2: 85-88. (Article in Spanish)

2010 Rojas C, Méndez L, Arab JP, Barrera F, Soza A, Nervi F, Duarte I, Pulgar M, Paredes N, Molgó M, Amador R, Cariqueo M, Riquelme A. DRESS syndrome. Skin rash, fever and hepatitis associated with lamotrigine. Report of 2 cases and review of the literature. Gastroenterol. latinoam 2010; Vol 21, Nº 3: 357-362. (Article in Spanish)

2010 Arab JP, Ramírez C, Gran I, Riquelme A, Arrese M. Treatment of nonalcoholic fatty liver: What do we know? Gastroenterol. latinoam 2010; Vol 21, Nº 3: 344-349. (Article in Spanish)

2011 Huebert RC, Jagavelu K, Hendrickson HI, Vasdev MM, Arab JP, Splinter PL, Trussoni CE, Larusso NF, Shah VH. Aquaporin-1 Promotes Angiogenesis, Fibrosis, and Portal Hypertension Through Mechanisms Dependent on Osmotically Sensitive MicroRNAs. Am J Pathol. 2011 Oct;179(4):1851-60

2011 Espino A, Villagrán A, Vollrath V, Hanckes P, Salas R, Farah A, Solís N, Pizarro M, Escalona A, Boza C, Pérez G, Carrasco G, Padilla O, Miquel JF, Nervi F, Chavez-Tapia NC, Arab JP, Alvarez-Lobos M, Arrese M, Riquelme A. Plasminogen activator inhibitor type 1 serum levels and 4G/5G gene polymorphism in morbidly obese Hispanic patients with non-alcoholic fatty liver disease. Ann Hepatol. 2011 Oct 1;10(4):493-501.

2011 Arab JP, Farah A, Pizarro M, Solis N, M, Tejos R, Riquelme A, Arrese M. Impaired biliary secretory function in experimental hepatic steatosis. Gastroenterol. latinoam 2011; Vol 22, Nº 4: 296-30. (Article in Spanish)

2012 Rojas L, Aizman A, Arab JP, Utili F, Andresen M. [Basic cardiopulmonary resuscitation: knowledge, practical skills and effectiveness of maneuvers of general physicians]. Rev Med Chile 2012; 140: 73-77. (Article in Spanish)

2012 Arab JP, Zapata JM, Ruiz MI, Bretón A, Palma S, Emperiale V, Astudillo P, Arrese M. Intravenous N-acetylcysteine improves transplant-free survival in early stages of no-acetaminophen acute liver failure. Gastroenterol. latinoam 2012; Vol 23, Nº 2: 110-112. (Article in Spanish)

2012 Arab JP, Ramírez C, Arriagada C, Callejas M, Arrese M. Pioglitazone, vitamin E or placebo for the treatment of nonalcoholic steatohepatitis. Gastroenterol. latinoam 2012; Vol 23, Nº 3: 170-172. (Article in Spanish)

2013 Tejos R, Padilla O, Pizarro M, Solis N, Arab JP, Margozzini P, Miquel JF, Riquelme A, Arrese M. Serum levels of alanine aminotransferase in Chilean population: analysis of results of the national health survey 2009-2010. Rev Med Chile 2013;141:905-912. (Article in Spanish)

2013 Arab JP, Meneses L, Pérez RM, Arrese M, Benítez C. Hepatic encephalopathy in a liver transplant recipient with stable liver function. Hepatology 2013 Apr; 57(4): 1672-4.

2014 Solis N, Pizarro M, Quintero P, Arab JP, Riquelme A, Padilla O, Carrasco G, Pirola C, Sookoian S, Arrese M. Effects of bile acid sequestration on hepatic steatosis in obese mice. Annals of Hepatology 2014; 13(1):105-112.

2014 Quintero P, Pizarro M, Solis N, Arab JP, Padilla O, Riquelme A and Arrese M. Bile acid supplementation improves established liver steatosis in obese mice independently of GLP-1 secretion. J Physiol Biochem. 2014 Sep;70(3):667-74.

2014 Rollán A, Arab JP, Camargo MC, Candia R, Harris P, Ferreccio C, Rabkin CS, Gana JC, Cortés P, Herrero R, Durán L, García A, Toledo C, Espino A, Lustig N, Sarfatis A, Figueroa C, Torres J, Riquelme A. Management of Helicobacter pylori Infection in Latin America: A Delphi-based Consensus. World J Gastroenterol 2014; 20(31): 10969-10983.

2014 Arab JP, Candia R, Zapata R, Muñoz C, Arancibia JP, Poniachik J, Soza A, Fuster F, Brahm J, Sanhueza E, Contreras J, Cuellar MC, Arrese M and Riquelme A. Management of nonalcoholic fatty liver disease: an evidence-based clinical practice review. World J Gastroenterol 2014 September 14; 20(34): 12182-12201.

2014 Guarda FJ, Arab JP, Ramírez C, Arrese M. Imagen del mes: “Pulmonary embolism due to migration of cyanoacrylate as a complication of treatment of gastrointestinal bleeding secondary to gastric varices”. Gastroenterol. latinoam 2014; Vol 25, Nº 1: 43-44 (Article in Spanish)

2014 Olmos P, Donoso A, Arab JP, Niklitschek I, Mertens N, Arce E, Lemus R, Serrano V, Grassi B, Strodthoff K, Abbott E, Aizman A, González MV. [Treatment of diabetic ketoacidosis using 2009 American Diabetes Association guidelines]. Rev Med Chil. 2014 Oct;142(10):1267-74. (Article in Spanish).

2014 Arab JP, Schalper K y Arrese M. Histological scoring system for nonalcoholic fatty liver disease: NAFLD activity score (NAS). Gastroenterol. Latinoam 2014; Vol 25, Nº4:308-313. (Article in Spanish)

2015 Arab JP, Vargas JI, Morales C, Arrese M. Black hairy tongue during interferon therapy for Hepatitis C. Annals of Hepatology 2015 May-Jun;14(3):414-5.

2015 Martínez J, Besa S, Arab JP, Quintana JC, Regonesi C, Jarufe N, Guerra JF, Benítez C, Arrese M. Gastrointestinal neuroendocrine tumor with unresectable liver metastases: an example of multimodal therapeutic approach. Annals of Hepatology 2015 Sep-Oct;14(5):752-5.

2015 Pizarro M, Solis N, Quintero P, Barrera F, Cabrera D, Rojas-de Santiago P, Arab JP, Padilla O, Roa JC, Moshage H, Wree A, Inzaugarat E, Feldstein AE, Fardella CE, Baudrand R, Riquelme A, Arrese M. Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis. Liver Int 2015 Sep;35(9):2129-38

2015 Aguirre-Reyes DF, Sotelo JA, Arab JP, Arrese M, Tejos R, Irarrazaval P, Tejos C, Uribe SA, Andia ME. Intrahepatic portal vein blood volume estimated by non-contrast Magnetic Resonance Imaging for the assessment of portal hypertension. Magn Reson Imaging 2015 Oct;33(8):970-7.

2015 Zamora M, Herrera S, Yáñez G, Arab JP, Riquelme A. The association of a probiotic to eradication of Helicobacter pylori regime does not increase the efficacy nor reduces adverse effects of treatment. Gastroenterología Latinoamericana 2015 (in press). (Article in Spanish)

2015 Figueroa C, Calvo I, González C, Sandoval D, Padilla O, Le Roy C, Delfino A, Arab JP, Pizarro M, Solís N, Riquelme A. [Introduction of virtual patients to clinical case portfolios for undergraduate medical students]. Rev Med Chil. 2015 Feb;143(2):175-82. [Article in Spanish].

2015 Pizarro M, Solís N, Rojas V, Díaz LA, Padilla O, Letelier LM, Aizman A, Sarfatis A, Olivos T, Soza A, Delfino A, Latorre G, Ivanovic-Zuvic D, Hoyl T, Bitrán M, Arab JP and Riquelme A. [Development of MEDUC-PG14 survey to assess postgraduate teaching in medical specialties]. Rev Med Chil. 2015; 143:907-916. [Article in Spanish].

2015 Pérez G, Kattan E, Collins L, Wright AC, Rybertt T, González A, Sirhan M, Solís N, Pizarro M, Arrese M, Sarfatis A, Lustig N, Arab JP, Labarca J, Riquelme A. [Assessment for learning: experience in an undergraduate medical theoretical course]. Rev Med Chil. 2015 Mar;143(3):329-336. [Article in Spanish].

2015 Puente I, Salas S, Diez de Medina C, Pérez MI, Salinas R, Rivas A, Arab JP. Strategies for the eradication of Helicobacter pylori in Latin America. Gastroenterol. Latinoam 2015; 26(4):270-273. [Article in Spanish].

2015 Arab JP, Diaz LA, Veliz D, Riquelme A, Gonzalez M. Evaluación de docentes y jefes de programas de residencia en posgrado. Inv Ed Med 2015;4:e22

2015 Arab JP, Veliz D, Diaz LA, Riquelme A, Gonzalez M. Retroalimentación del desempeño del residente en programas de formación de especialidad y subespecialidad. Inv Ed Med 2015;4:e21.

2015 Arab JP, Veliz D, Diaz LA, Riquelme A, Gonzalez M. Carga laboral horaria en residentes de especialidad y subespecialidad. Inv Ed Med 2015;4:e21-2

2016 Fuster F, Vargas JI, Jensen D, Sarmiento V, Acuña P, Peirano F, Fuster F, Arab JP, Martínez F, CORE-HIV Study Group. CD4/CD8 ratio as a predictor of the response to HBV vaccination in HIV-positive patients: a prospective cohort study. Vaccine 2016 Apr 7;34(16):1889-95.

2016 Arab JP, Shah VH. Statins and portal hypertension: A tale of two models. HEPATOLOGY 2016 Jun;63(6):2044-7.

2016 Arab JP, Barrera F, Gallego C, Valderas JP, Uribe S, Tejos C, Serrano C, Huete A, Liberona J, Labbe P, Quiroga T, Riquelme A, Benítez C, Irarrazabal P, Arrese M. High prevalence of undiagnosed liver cirrhosis and advanced fibrosis in type 2 diabetic outpatients. Annals of Hepatology 2016 Sep-Oct;15(5):721-8.

2016 Arab JP, Claro JC, Arancibia JP, Contreras J, Gómez F, Muñoz C, Nazal L, Roessler E, Wolff R, Arrese M, Benítez C. Therapeutic alternatives for the treatment of type 1 hepatorenal syndrome: A Delphi technique-based consensus. World Journal of Hepatology 2016; 8(25): 1075-1086.

2016 Vargas JI, Arab JP, Jensen D, Fuster F. Achieving protection against HBV in HIV patients: finding the best strategy. Human Vaccines & Immunotherapeutics 2016 Dec;12(12):3166-3167.

2016 Hernández-Rocha C, Pidal P, Ajenjo MC, Quera R, Quintanilla M, Lubascher J, Jemenao M, Ibáñez P, Álvarez-Lobos M, Diomedi A, Marcotti A, Acuña M, Arab JP, Riquelme A, Candia R, Carvajal S. Chilean consensus of prevention, diagnosis and treatment of Clostridium difficile-associated diarrhea. Rev Chil Infectol 2016; 33 (1): 98-118

2016 Bustamante V, Arab JP, Terc F, Poggi H, Goycoolea M, Arrese M, Quiroga T, Benítez C. Persistent elevation of aspartate aminotransferase (AST) due to the presence of macro-AST: Report of one case. Rev Med Chil 2016 Aug;144(8):1078-1082. [Article in Spanish].

2016 Diaz LA, Arab JP, Cotoras P, Veliz D, Bitran M, Rojas V, Lopetegui M, Torres P, Gonzalez P, Hoyl MT, Riquelme A. Evaluación de la carga laboral en residentes chilenos de especialidades y subespecialidades médicas. ARS MEDICA Revista de Ciencias Médicas, [S.l.], v. 41, n. 2, p. 13-20, oct. 2016. ISSN 0719-1855. doi: http://dx.doi.org/10.11565/arsmed.v41i2.109. [Article in Spanish]

2017 Arab JP, Karpen SJ, Dawson PA, Arrese M, Trauner M. Bile acids & nonalcoholic fatty liver disease: molecular insights and therapeutic perspectives. HEPATOLOGY 2017;65:350-362.

2017 Arab JP, Hernández-Rocha C, Morales C, Vargas JI, Solis N, Pizarro M, Robles C, Sandoval D, Ponthus S, Benítez C, Barrera F, Soza A, Riquelme A, Arrese M. Serum cytokeratin-18 fragment levels as noninvasive marker of nonalcoholic steatohepatitis in Chilean population. Gastroenterol Hepatol. 2017 Mar 27. pii: S0210-5705(17)30054-7. doi: 10.1016/j.gastrohep.2017.02.009. [Epub ahead of print]

2017 Cabrera D, Wree A, Povero D, Solis N, Hernandez A, Pizarro M, Moshage H, Torres J, Feldstein A, Cabello-Verrugio C, Brandan E, Barrera F, Arab JP, Arrese M. Andrographolide ameliorates inflammation and fibrogenesis and attenuates inflammasome activation in experimental non-alcoholic steatohepatitis. Scientific Reports 2017 Jun 14;7(1):3491.

2017 Vargas JI, Arrese M, Shah VH, Arab JP. Use of statins in patients with chronic liver disease and cirrhosis: current views and prospects. Current Gastroenterology Reports 2017 Sep;19(9):43.

2017 Arab JP, Cabrera D, Arrese M. Bile Acids in Cholestasis and its Treatment. Ann Hepatol. 2017 Oct 28;16(0):47-51.

2017 Arab JP, Barrera F, Arrese M. Bile Acids and Portal Hypertension. Ann Hepatol. 2017 Oct 28;16(0):77-80.

2017 Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, et al. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. JCI Insight 2017;2(24):e92821.

2017 Vargas JI, Arab JP, Bessone F, Lucena MI, Andrade RJ, Arrese M. Hepatotoxicity in Patients with Metabolic Syndrome: Causes and Consequences. Curr Hepatology Rep. 2017, 16: 286. https://doi.org/10.1007/s11901-017-0380-8.

2017 Diaz LA, Arab JP, Núñez C, Robles C, Bitran M, Nitsche MP, Veliz D, Lopetegui M, Torres P, Gonzalez P, Hoyl MT, Riquelme A. Burnout in residents of specialties and subspecialties: study of prevalence and associated variables in one university centre. ARS MEDICA Revista de Ciencias Médicas, [S.l.], v. 42, n. 2, p. 27-33, ago. 2017. ISSN 0719-1855. doi:http://dx.doi.org/10.11565/arsmed.v42i2.541. [Article in Spanish]

2017 Kinzel F, Böhm P, Sánchez A, Huenur J, Quinteros N, Vergara F, Arab JP. [A randomized controlled study of trimethoprim-sulfamethoxazole versus norfloxacin for the prevention of infection in cirrhotic patients]. Gastroenterologia Latinoamericana 2017; Vol 28, Nº 2: 102-106. [Article in Spanish]

2017 Vargas JI, Arab JP, Fuster F, Soza A. Nuevas terapias orales de acción directa para tratamiento de virus de hepatitis C (VHC): experiencia inicial en Chile. Rev Med Chile 2017; 145: 1235-1242.

2018 Arab JP, Martin-Mateos R, Shah VH. Gut-liver axis, cirrhosis and portal hypertension: the chicken & the egg. Hepatol Int. 2018 Feb;12(Suppl 1):24-33. doi: 10.1007/s12072-017-9798-x. Epub 2017 May 26.

2018 Arab JP, Arrese M, Trauner M. Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease. Annu. Rev. Pathol. Mech. Dis. 2018 Jan 24;13:321-350.

2018 Cabrera D, Cabello-Verrugio C, Solis N, San Martín D, Cofré C, Pizarro M, Arab JP, Abrigo J, Campos F, Irigoyen B, Carrasco-Avino G, Bezares K, Riquelme V, Riquelme A, Arrese M, Barrera F. Somatotropic axis dysfunction in non-alcoholic fatty liver disease: beneficial hepatic and systemic effects of hormone supplementation. Int J Mol Sci. 2018 May 2;19(5).

2018 Arab JP, Barrera F, Arrese M. The Evolving Role of Liver Biopsy in Non-alcoholic Fatty Liver Disease. Ann Hepatol. 2018 Oct 16;17(6):899-902.

2019 Arab JP, Arrese M. Old remedies to heal the liver: novel effects of digoxin in hepatic sterile inflammation. Hepatology 2019 Feb;69(2):904-906.

2019 Martin Mateos R, De Assuncao TM, Arab JP, Jalan-Sakrikar N, Yaqoob U, Greuter T, Verma V, Mathison AJ, Cao S, Lomberk G, Mathurin P, Urrutia R, Huebert RC, Shah VH. Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis. Cell Mol Gastroenterol Hepatol. 2019;7(1):197-209.

2019 Hilscher M, Sehrawat T, Arab JP, Zeng Z, Kostallari E, Gao Y, Simonetto D, Beyder A, Cao S, Kamath P, Kubes P, Shah V. CXCL1 drives portal hypertension by interfacing mechanosensing and angiocrine signals to generate sinusoidal microthombi. Gastroenterology 2019 Jul;157(1):193-209.

2019 Arab JP, Roblero JP, Altamirano J, Bessone F, Chaves Araujo R, Higuera-De la Tijera F, Restrepo JC, Torre A, Urzua A, Simonetto DA, Abraldes JG, Mendez-Sanchez N, Contreras F, Lucey MR, Shah VH, Cortez-Pinto H, Bataller R. Alcohol-related liver disease: Clinical Practice Guidelines by the Latin American Association for the Study of the Liver (ALEH). Annals of Hepatology 2019;18:518–535.

2019 Cabrera D, Arab JP, Arrese M. UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications. Handb Exp Pharmacol. 2019;256:237-264.

2019 Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, Fondevilla C, Stärkel P, Dubuquoy L, Louvet A, Odena G, Altamirano J, Caballeria J, Jurzak MJ, Lansing Taylor D, Berasain C, Wahlestedt C, Monga SP, Morgan MY, Sancho-Bru P, Mathurin P, Furuya S, Lackner C, Rusyn I, Shah VH, Thursz MR, Mann J, Avila MA, Bataller R. Defective HNF4a-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nature Communications 2019;10:3126.

2019 Estrada LD, Ahumada P, Cabrera D and Arab JP. Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain. Frontiers in Aging Neuroscience 2019;11:174.

2019 Arrese M, Barrera F, Triantafilo N, Arab JP. Concurrent nonalcoholic fatty liver disease and type 2 diabetes: diagnostic and therapeutic considerations. Expert Rev Gastroenterol Hepatol. 2019 Sep;13(9):849-866.

2019 Mindikoglu AL, Coarfa C, Opekun AR, Shah VH, Arab JP, Lazaridis KN, Putluri N, Reddy Ambati CS, Donepudi SR, Robertson MJ, Sreekumar A, Devaraj S, Vierling JM, Rana A, Goss JA, Mohney RP, Dowling TC, Howell CD, Christenson RH, Weir MR, Seliger SL, Raufman JP, Magder LS, Bernard DW, Vierling JM. Metabolomic Biomarkers Are Associated with Mortality in Patients with Cirrhosis Caused by Primary Biliary Cholangitis and Primary Sclerosing Cholangitis. Future Science OA 2019 Dec 17;6(2):FSO441.

2019 Arnold J, Gran JI, Baladrón MJ, Huete A, Torres J, Maquilon S, Meneses L, Riquelme A, Dib M, Arab JP. Image of the month: Focal lesions in the cirrhotic liver, it’s not all bad news. Gastroenterol. latinoam 2019; Vol 30, Nº 1: 39-43.

2020 Arab JP, Sehrawat TS, Simonetto DA, Verma VK, Feng D, Tang T, Dreyer K, Yan X, Daley WL, Sanyal A, Chalasani N, Radaeva S, Yang L, Vargas H, Ibacache M, Gao B, Gores GJ, Malhi H, Kamath PS, Shah VH. An open label, dose escalation study to assess the safety and efficacy of IL-22 agonist F-652 in patients with alcoholic hepatitis. HEPATOLOGY 2020 Aug;72(2):441-453.

2020 Arab JP, Arrese M, Shah VH. Gut microbiota in non-alcoholic fatty liver disease and alcohol-related liver disease: current concepts and perspectives. Hepatology Research. 2020 Apr;50(4):407-418.

2020 Gaete MI, Díaz LA, Arenas A, González K, Cattaneo M, Fuster F, Henríquez R, Soza A, Arrese M, Barrera F, Arab JP, Benítez C. Baveno VI and Expanded Baveno VI criteria succesfully predicts the absence of high-risk gastro-oesophageal varices in a Chilean cohort. Liver Int. 2020 Jan 8. doi: 10.1111/liv.14373.

2020 Arab JP, Cabrera D, Sehrawat T, Verma VK, Jalan-Sakrikar N, Simonetto DA, Cao S, Yaqoob U, Leon J, Freire M, Vargas JI, De Assuncao TM, Kwon JH, Guo Y, Arrese M, Huebert RC, Shah VH. Hepatic stellate cell activation promotes alcohol induced steatohepatitis demonstrating bi-directional crosstalk with hepatocytes. Journal of Hepatology 2020 Jul;73(1):149-160.

2020 Hernandez A, Geng Y, Sepulveda R, Solis N, Torres J, Arab JP, Barrera F, Cabrera D, Moshage H and Arrese M. Chemical Hypoxia induces pro-inflammatory signals in fat-laden hepatocytes and contributes to cellular crosstalk with Kupffer cells through extracellular vesicles. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2020; 1866(6):165753.

2020 Hernandez A, Arab JP, Reyes D, Lapitz A, Moshage H, Bañales J, Arrese M. Extracellular vesicles in NAFLD/ALD: from pathophysiology to therapy. Cells 2020 Mar 27;9(4):E817.

2020 Singal AK, Ahmed Z, Axley P, Arora S, Arab JP, Haas A, Kuo YF, Kamath PS. Hospitalizations for Acute on Chronic Liver Failure at Academic Compared to Non-Academic Centers Have Higher Mortality. Digestive Diseases and Sciences 2020 Apr 21. doi: 10.1007/s10620-020-06263-w.

2020 Benítez C, Inzunza M, Riveros S, Rivas V, Garrido M, Dib M, Barrera F, Arab JP, Torres J, Cortinez I, Briceño E, Guerra JF, Fernandes E, Martínez JA. First Report of Living Donor Liver Transplantation for Imatinib-Resistant GIST Liver Metastases. A new therapeutic option in Transplant Oncology. Liver Transplantation 2020 Apr 4. doi: 10.1002/lt.25769.

2020 Sehrawat TS, Arab JP, Liu M, Amrollahi P, Wan M, Fan J, Nakao Y, Pose E, Navarro-Corcuera A, Dasgupta D, Liao CY, He L, Mauer AS, Avitabile E, Ventura-Cots M, Bataller RA, Sanyal AJ, Chalasani NP, Heimbach JK, Watt KD, Gores GJ, Gines P, Kamath PS, Simonetto DA, Hu TY, Shah VH, Malhi H. Circulating extracellular vesicles carrying sphingolipid cargo for the diagnosis and dynamic risk profiling of alcoholic hepatitis. HEPATOLOGY 2020 Apr 4. doi: 10.1002/hep.31256.

2020 Fondevila MF, Fernandez U, Gonzalez-Rellan MJ, Lima N, Buque X, Gonzalez-Rodriguez A, Alonso C, Iruarrizaga-Lejarreta M, Delgado TC, Varela-Rey M, Senra A, Garcia-Outeiral V, Novoa E, Iglesias C, Porteiro B, Beiroa D, Folgueira C, Tojo M, Torres JL, Hernández-Cosido L, Blanco O, Arab JP, Barrera F, Guallar D, Fidalgo M, López M, Dieguez C, Marcos M, Martinez-Chantar ML, Arrese M, Garcia-Monzon C, Mato JM, Aspichueta P, Nogueiras R. The L-α-lysophosphatidylinositol/GPR55 system induces the development of non-alcoholic steatosis and steatohepatitis. HEPATOLOGY 2020 Apr 23. doi: 10.1002/hep.31290.

2020 Yaqoob U, Luo F, Greuter T, Sakrikar NJ, Sehrawat TS, Lu J, Hu X, Gao J, Kostallari E, Chen J, Arab JP, Cao S, Shah VH. GIPC-regulated IGFBP-3 Promotes HSC Migration in Vitro and Portal Hypertension in Vivo Through a β1-integrin Pathway. Cell Mol Gastroenterol Hepatol. 2020 May 21:S2352-345X(20)30075-8.

2020 Hernández A, Reyes D, Geng Y, Arab JP, Cabrera D, Sepulveda R, Solis N, Buist-Homan M, Arrese M, Moshage H. Extracellular Vesicles Derived From Fat-Laden Hepatocytes Undergoing Chemical Hypoxia Promote a Pro-Fibrotic Phenotype in Hepatic Stellate Cells. Biochim Biophys Acta Mol Basis Dis. 2020 Jun 5:165857.

2020 Urzúa A, Arab JP, Barrera F, Castro N, Gómez F, González K, Lazarte R, Mezzano G, Roblero JP, Nazal L. Recommendations for the management of patients with chronic liver disease and liver transplanted recipients during the COVID-19 pandemic [Recomendaciones para manejo de pacientes con enfermedad hepática crónica y trasplantados hepáticos durante pandemia por COVID-19]. Gastroenterol. latinoam 2020; Vol 31, Nº 1: 28-34.

2020 Kulkarni AV, Kumar P, Tevethia HV, Premkumar M, Arab JP, Candia R, Talukdar R, Sharma M, Qi X, Rao PN, Reddy DN. Systematic review with meta-analysis: liver manifestations and outcomes in COVID-19. Aliment Pharmacol Ther. 2020 Jul 8. doi: 10.1111/apt.15916

2020 Fernández-Mincone T, Contreras-Briceño F, Espinosa-Ramírez M, García-Valdés P, López-Fuenzalida A, Riquelme A, Arab JP, Cabrera D, Arrese M, Barrera F. Non-alcoholic fatty liver disease and sarcopenia: pathophysiological connections and therapeutic implications. Expert Rev Gastroenterol Hepatol. 2020 Aug 19. doi: 10.1080/17474124.2020.1810563.

2020 Idalsoaga F, Kulkarni AV, Mousa OY, Arrese M, Arab JP. Non-alcoholic Fatty Liver Disease and Alcohol-Related Liver Disease: Two Intertwined Entities. Front. Med. 2020. 7:448. doi: 10.3389/fmed.2020.00448

2020 Arab JP, Bataller R, Roblero JP. Are we really taking care of alcoholic liver disease in Latin America? Clinical Liver Disease 2020 Sep 22;16(3):91-95.

2020 Diaz LA, Roblero JP, Bataller R, Arab JP. Alcohol-related liver disease in Latin America: Local solutions for a global problem. Clinical Liver Disease. 2020;16(5):187-190.

2020 Asrani SK, Mellinger J, Arab JP, Shah VH. Reducing the Global Burden of Alcohol-Associated Liver Disease: A Blueprint for Action. HEPATOLOGY. 2020 Sep 28. doi: 10.1002/hep.31583

2020 Kulkarni AV, Kumar P, Tevethia HV, Arab JP, Candia R, Premkumar M, Sharma M, Rao PN, Reddy DN. Letter: elevated liver enzymes and outcomes in COVID Authors' reply. Aliment Pharmacol Ther. 2020 Oct;52(7):1235-1236.

2020 Li J, Sehrawat TS, Chen J, Hilscher MB, Glaser KJ, Arab JP, De Assuncao TM, Simonetto DA, Mounajjed T, Manduca A, Ehman RL, Shah VH, Yin M. Quantitative assessment of portal hypertension with bi-parametric dual-frequency hepatic MR elastography in mouse models. Eur Radiol. 2020 Oct 7. doi: 10.1007/s00330-020-07341-3.

2020 Arab JP, Dirchwolf M, Álvares-da-Silva MR, Barrera F, Benítez C, Castellanos-Fernandez M, Castro-Narro G, Chavez-Tapia N, Chiodi D, Cotrim H, Cusi K, de Oliveira CPMS, Díaz J, Fassio E, Gerona S, Girala M, Hernandez N, Marciano S, Masson W, Mendez-Sanchez N, Leite N, Lozano A, Padilla M, Panduro A, Paraná R, Parise E, Perez M, Poniachik J, Restrepo JC, Ruf A, Silva M, Tagle M, Tapias M, Torres K, Vilar-Gomez E, Costa Gil JE, Gadano A, Arrese M. Latin American Association for the Study of the Liver (ALEH) Practice Guidance for the Diagnosis and Treatment of Non-Alcoholic Fatty Liver Disease. Ann Hepatol. 2020 Oct 5;S1665-2681(20)30177-0.

2020 Kulkarni AV, Arab JP, Premkumar M, Benítez C, Sowmya TR, Kumar P, Sharma M, Nageshwar Reddy D, Simonetto DA, Rao PN. Terlipressin has stood the test of time: Clinical Overview in 2020 and Future Perspectives. Liver Int. 2020 Oct 16. doi: 10.1111/liv.14703

2020 Im GY, Mellinger JL, Winters A, Aby ES, Lominadze Z, Rice J, Lucey MR, Arab JP, Goel A, Jophlin LL, Sherman CB, Parker R, Chen PH, Devuni D, Sidhu S, Dunn W, Szabo G, Singal AK, Shah VH. Provider Attitudes and Practices for Alcohol Screening, Treatment and Education in Patients with Liver Disease: a Survey from the AASLD ALD SIG. Clin Gastroenterol Hepatol. 2020 Oct 15;S1542-3565(20)31439-7. doi: 10.1016/j.cgh.2020.10.026.

2020 Izzy M, Addissie BD, Arab JP, Hilscher MB, Cartee A, Lee DC, Lee Y, Fletcher JG, Keaveny TM, Sanchez W. Triple Phase CT May Replace Dual-energy X-ray Absorptiometry Scan For Evaluation of Osteoporosis in Liver Transplant Candidates. Liver Transpl. 2020 Oct 23. doi: 10.1002/lt.25926.

2020 Waleed M, Abdallah MA, Kuo YF, Arab JP, Wong R, Singal AK. Higher frequency of hospital acquired infections but similar in-hospital mortality among admissions with alcoholic hepatitis at academic vs. non-academic centers. Frontiers in Physiology 2020 Dec 3;11:594138.

2020 Díaz LA, Idalsoaga F, Cannistra M, Candia R, Cabrera D, Barrera F, Soza A, Graham R, Riquelme A, Arrese M, Leise MD, Arab JP. High prevalence of hepatic steatosis and vascular thrombosis in COVID-19: A systematic review and meta-analysis of autopsy data. World J Gastroenterol Dec 28, 2020; 26(48): 7693-7706.

2021 Mendez-Sanchez N, Arrese M, Gadano A, Oliveira CP, Fassio E, Arab JP, Chávez-Tapia NC, Dirchwolf M, Torre A, Ridruejo E, Pinchemel-Cotrim H, Castellanos Fernández MI, Uribe M, Girala M, Diaz-Ferrer J, Restrepo JC, Padilla-Machaca M, Dagher L, Gatica M, Olaechea B, Pessôa MG, Silva M. The Latin American Association for the Study of the Liver (ALEH) position statement on the redefinition of fatty liver disease. Lancet Gastroenterol Hepatol. 2021 Jan;6(1):65-72. doi: 10.1016/S2468-1253(20)30340-X. Epub 2020 Nov 9.

2021 Parker R, Cabezas J, Altamirano J, Arab JP, Ventura-Cots M, Sinha A, Dhanda A, Arrese M, McCune CA, Rowe IA, Schnabl B, Mathurin P, Shawcross D, Abraldes JJ, Lucey MR, Garcia-Tsao G, Verna E, Brown RS Jr, Bosques-Padilla F, Vargas V, Louvet A, Holt AP, Bataller R. Trajectory of Serum Bilirubin Predicts Spontaneous Recovery in a Real-World Cohort of Patients with Alcoholic Hepatitis. Clin Gastroenterol Hepatol. 2021 Jan 28;S1542-3565(21)00092-6.

2021 Kulkarni AV, Tevethia HV, Arab JP, Candia R, Premkumar M, Kumar P, Sharma M, Reddy DN, Padaki NR. Efficacy and safety of obeticholic acid in liver disease-A systematic review and meta-analysis. Clin Res Hepatol Gastroenterol. 2021 Mar 12;101675.

2021 Lonardo A, Arab JP, Arrese M. Perspectives on Precision Medicine Approaches to NAFLD Diagnosis and Management. Advances in Therapy. 2021 May;38(5):2130-2158

2021 Cabrera D, Rao I, Raasch F, Solis N, Pizarro M, Freire M, Sáenz De Urturi D, Ramírez CA, Triantafilo N, León J, Riquelme A, Barrera F, Baudrand R, Aspichueta P, Arrese M, Arab JP. Mineralocorticoid receptor modulation by dietary sodium influences NAFLD development in mice. Ann Hepatol. 2021 Apr 30:100357. doi: 10.1016/j.aohep.2021.100357.

2021 Arab JP, Arrese M, Singal AK. Diagnosis of alcohol-associated hepatitis: when is liver biopsy required? Clin Liver Dis. 2021 Aug;25(3):571-584.

2021 He L, Sehrawat TJ, Verma VK, Navarro-Corcuera A, Luo X, Katsumi T, Chen J, Arab JP, Cao S, Shah S, Shah VH. XIAP knockdown in alcohol-associated liver disease models exhibits divergent in vitro and in vivo phenotypes owing to a potential zonal inhibitory role of SMAC. Frontiers in Physiology 2021 May 7;12:664222.

2021 Quezada N, Valencia I, Torres J, Maturana G, Cerda J, Arab JP, Fuentes JJ, Pinto C, Turiel D, Cortés V. Insulin resistance and liver histopathology in metabolically unhealthy subjects do not correlate with the hepatic abundance of NLRP3 inflammasome nor circulating IL-1β levels. BMJ Open Diabetes Research & Care 2021 May;9(1):e001975. doi: 10.1136/bmjdrc-2020-001975.

2021 Vargas JF, Arab JP. Pulsatile epigastric mass and liver masses in a 38-year-old patient with splenomegaly since childhood. Gastroenterology Apr 27:S0016-5085(21)00693-4. doi: 10.1053/j.gastro.2021.04.055.

2021 Arab JP, Diaz LA, Baeza N, Idalsoaga F, Fuentes-López E, Arnold J, Ramírez CA, Morales-Arraez D, Ventura-Cots M, Alvarado-Tapias E, Zhang W, Clark V, Simonetto D, Ahn JC, Buryska S, Mehta TI, Stefanescu H, Horhat A, Bumbu A, Dunn W, Attar B, Agrawal R, Haque ZS, Majeed M, Cabezas J, García-Carrera I, Parker R, Cuyàs B, Poca M, Soriano G, Sarin SK, Maiwall R, Jalal PK, Abdulsada S, Higuera-de la Tijera MF, Kulkarni AV, Rao PN, Guerra Salazar P, Skladaný L, Bystrianska N, Prado V, Clemente-Sanchez A, Rincón D, Haider T, Chacko KR, Cairo F, Coelho MS, Romero GA, Pollarsky FD, Restrepo JC, Castro-Sanchez S, Toro LG, Yaquich P, Mendizabal M, Garrido ML, Narvaez A, Bessone F, Santiago Marcelo J, Piombino D, Dirchwolf M, Arancibia JP, Altamirano J, Kim W, Araujo RC, Duarte Rojo A, Vargas V, Rautou PE, Issoufaly T, Zamarripa F, Torre A, Lucey MR, Mathurin P, Louvet A, García-Tsao G, González JA, Verna E, Brown RS, Roblero JP, Abraldes JG, Arrese M, Shah VH, Kamath PS, Singal AK, Bataller R. Identification of optimal therapeutic window for steroid use in severe alcohol-associated hepatitis: A worldwide study. Journal of Hepatology. 2021 Jun 21;S0168-8278(21)00439-6.

2021 Arab JP, Díaz LA, Dirchwolf M, Mark H, Lazarus JV, Vaughan E, Méndez-Sánchez N, de Oliveira CP, Gadano A, Arrese M. NAFLD: Challenges and opportunities to address the public health challenge in Latin America. Ann Hepatol. 2021 May 15;24:100359.

2021 Díaz LA, Idalsoaga F, Fuentes-López E, Márquez-Lomas A, Ramírez CA, Roblero JP, Araujo RC, Higuera-de-la-Tijera F, Toro LG, Pazmiño G, Montes P, Hernandez N, Mendizabal M, Corsi O, Ferreccio C, Lazo M, Brahmania M, Singal AK, Bataller R, Arrese M, Arab JP. Impact of public health policies on alcohol-associated liver disease in Latin America: An ecological multi-national study. Hepatology. 2021 Nov;74(5):2478-2490.

2021 Singal AK, Arsalan A, Dunn W, Arab JP, Wong RJ, Kuo YF, Kamath PS, Shah VH. Alcohol-associated liver disease in the United States is associated with severe forms of disease among young, females and Hispanics. Aliment Pharmacol Ther. 2021 Aug;54(4):451-461.

2021 Arrese M, Arab JP, Barrera F, Kaufmann B, Valenti L, Feldstein AE. Insights into Nonalcoholic Fatty-Liver Disease Heterogeneity. Semin Liver Dis. 2021 Jul 7. doi: 10.1055/s-0041-1730927.

2021 Kulkarni AV, Tevethia HV, Premkumar M, Arab JP, Candia R, Kumar K, Kumar P, Sharma M, Rao PN, Reddy DN. Impact of COVID-19 on liver transplant recipients-A systematic review and meta-analysis. EClinicalMedicine. 2021 Aug;38:101025.

2021 Liu M, Cao S, He L, Gao J, Arab JP, Cui H, Xuan W, Gao Y, Sehrawat TS, Hamdan FH, Ventura-Cots M, Argemi J, Pomerantz WCK, Johnsen SA, Lee JH, Gao F, Ordog T, Mathurin P, Revzin A, Bataller R, Yan H, Shah VH. Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis. Nat Commun. 2021 Jul 27;12(1):4560.

2021 Singal AK, Arsalan A, Dunn W, Arab JP, Wong RJ, Kuo YF, Kamath PS, Shah VH. Editorial: trends in alcohol use and alcohol-associated liver disease in the US population-authors' reply. Aliment Pharmacol Ther. 2021 Aug;54(4):513-514.

2021 Vargas JI, Jensen D, Martínez F, Sarmiento V, Peirano F, Acuña P, Provoste F, Bustos V, Cornejo F, Fuster A, Acuña M, Fuster F, Soto S, Estay D, Jensen W, Ahumada R, Arab JP, Soza A, Fuster F. Comparative Efficacy of a High-Dose vs Standard-Dose Hepatitis B Revaccination Schedule Among Patients With HIV: A Randomized Clinical Trial. JAMA Netw Open. 2021 Aug 2;4(8):e2120929.

2021 Lazarus JV, Mark HE, Anstee QM, Arab JP, Batterham R, Castera L, Cortez-Pinto H, Crespo Garcia J, Cusi K, Ashworth Dirac M, Franque S, George J, Hagström H, Huang T, Ismail MH, Kautz A, Sarin SK, Loomba R, Miller V, Newsome P, Ninberg M, Ocama P, Ratziu V, Rinella M, Romero D, Romero-Gómez M, Schattenberg JM, Tsochatzis EM, Valenti L, Wong V, Yilmaz Y, Younossi ZM, Zelber-Sagi S, on behalf of the NAFLD consensus statement collaborators. Advancing the global public health agenda for NAFLD: a consensus statement. Nat Rev Gastroenterol Hepatol. 2021 Oct 27. doi: 10.1038/s41575-021-00523-4.

2021 Roblero JP, Díaz LA, Arab JP, Roblero P, Bataller R. Socioeconomic inequalities in the incidence of alcohol-related liver disease in the Latin American. The Lancet Regional Health – Europe 2021 Oct 26;10:100229.

2021 Roblero JP, Arab JP, Mezzano G, Mendizabal M. Hepatitis C virus infection: What are we currently doing in Latin-America about WHO's proposals for 2030? Clinical Liver Disease 2021 Sep 19;18(2):72-75.

2021 Vargas JI, Rivera K, Arrese M, Benitez C, Barrera F, Hugo M, Arab JP, Pino K, Barrera A, Lopez-Lastra M, Rigotti A, Soza A. LDL particle size and antioxidant HDL function improve after sustained virological response in patients with chronic HCV. Ann Hepatol. 2021 Oct 6:100555. doi: 10.1016/j.aohep.2021.100555.

2021 Idalsoaga F, Ayares G, Arab JP, Díaz LA. COVID-19 and Indirect Liver Injury: A Narrative Synthesis of the Evidence. J Clin Transl Hepatol. 2021 Oct 28;9(5):760-768.

2021 Arab JP, Izzy M, Leggio L, Bataller R, Shah VH. Management of Alcohol Use Disorder in Patients with Cirrhosis and Liver Transplantation. Nature Reviews Gastroenterology & Hepatology 2021 Nov 1:1-15.

2021 Schneekloth TD, Arab JP, Simonetto DA, Petterson TM, Niazi SK, Hall-Flavin DK, Karpyak VM, Kolla BP, Roth JE, Kremers WK, Rosen CB. Factors Having an Impact on Relapse and Survival in Transplant Recipients With Alcohol-Induced Liver Disease. Mayo Clin Proc Innov Qual Outcomes. 2021 Dec 8;5(6):1153-1164.

2021 Morales-Arráez D, Ventura-Cots M, Altamirano J, Abraldes JG, Cruz-Lemini M, Thursz MR, Atkinson SR, Sarin SK, Kim W, Chavez-Araujo R, Higuera-de la Tijera MF, Singal AK, Shah VH, Kamath PS, Duarte-Rojo A, Charles EA, Vargas V, Jager M, Rautou PE, Rincon D, Zamarripa F, Restrepo-Gutiérrez JC, Torre A, Lucey MR, Arab JP, Mathurin P, Louvet A, García-Tsao G, González JA, Verna EC, Brown RS Jr, Argemi J, Fernández-Carillo C, Clemente A, Alvarado-Tapias E, Forrest E, Allison M, Bataller R. The MELD Score Is Superior to the Maddrey Discriminant Function Score to Predict Short-Term Mortality in Alcohol-Associated Hepatitis: A Global Study. Am J Gastroenterol. 2021 Dec 28. doi: 10.14309/ajg.0000000000001596.

2022 Díaz LA, Fuentes-López E, Lazo M, Kamath PS, Arrese M, Arab JP. Vaccination against COVID-19 decreases hospitalizations in patients with cirrhosis: Results from a nationwide analysis. Liver Int. 2022 Feb 7. doi: 10.1111/liv.15193.

2022 Kezer CA, Buryska SM, Ahn JC, Harmsen WS, Dunn W, Singal AK, Arab JP, Díaz LA, Arnold J, Kamath PS, Shah VH, Simonetto DA. The Mortality Index for Alcohol-Associated Hepatitis: A Novel Prognostic Score. Mayo Clin Proc. 2022 Feb 3:S0025-6196(21)00851-X. doi: 10.1016/j.mayocp.2021.10.026.

2022 Ayares G, Arab JP, Singal AK. Sending an SOS: Healing the Liver with the Bone Marrow. J Clin Transl Hepatol. 2022 Feb 28;10(1):1-3.

2022 Villalón A,Díaz LA, Fuentes-López E, Villalón J, Villalón F, Ayares G, Yañez B, Candia R, Arrese M, Arab JP. Colorectal Adenomas and MAFLD: A Cross-Sectional Study in a Hispanic Screening Cohort. Metab Target Organ Damage 2022;2:3. http://dx.doi.org/10.20517/mtod.2022.XX

2022 Arrese M, Cabello-Verrugio C, Arab JP, Barrera F, Baudrand R, Guarda FJ, Gul I, Cabrera D. Sarcopenia in the setting of nonalcoholic fatty liver. Metab Target Organ Damage 2022;2:2. http://dx.doi.org/10.20517/mtod.2021.16

2022 Díaz, LA, Fuentes-López E, Ayares G, Idalsoaga F, Arnold J, Márquez-Lomas A, Ramírez CA, Medel MP, Viñuela F, Lacalle L, Roblero JP, Ferreccio C, Lazo M, Brahmania M, Singal AK, Dirchwolf M, Méndez-Sánchez N, Chavez-Tapia N, Guerra P, Restrepo JC, Oliveira CP, Lombardo J, Sánchez A, Elizondo M, Tagle M, Padilla M, Sánchez M, Carrera E, Girala M, Chery O, Castellanos-Fernández M, Barrera F, Lazarus JV, Kamath PS, Bataller R, Arrese M, Arab JP. The establishment of Public Health Policies and Burden of Non-alcoholic fatty liver disease (NAFLD) in the Americas. Lancet Gastroenterol Hepatol. 2022 Apr 14:S2468-1253(22)00008-5.

2022 Singal AK, Kuo YF, Arab JP, Bataller R. Racial and Health Disparities among Cirrhosis-related Hospitalizations in the USA. J Clin Transl Hepatol. Published online: Jan 4, 2022. doi: 10.14218/JCTH.2021.00227.

2022 Tomlinson JL, Ahn JC, Povero D, Ramkissoon R, Ilyas SI, Arab JP. Hepatology Highlights. Hepatology. 2022 Apr;75(4):775-776.

2022 Arab JP, Castro L, Gómez PC, Vignolo P, Arrese M, Barrera F, Castro F, Díaz LA, Donoso A, Elgueta K, González K, González MI, Moreno M, Lazarte R, Poniachik J, Salman P, Valderas JP. [Non-alcoholic fatty liver disease in type 2 diabetes: a joint statement of the Chilean Hepatology and Diabetology Societies]. Rev Med Chil. 2021 Sep;149(9):1360-1371.

2022 Meza V, Arnold J, Díaz LA, Ayala Valverde M, Idalsoaga F, Ayares G, Devuni D, Arab JP. Alcohol Consumption: Medical Implications, the Liver and Beyond. Alcohol Alcohol. 2022 Mar 25:agac013.

2022 Rojas YAO, Cuellar CLV, Barrón KMA, Arab JP, Miranda AL. Non-alcoholic fatty liver disease prevalence in Latin America: A systematic review and meta-analysis. Ann Hepatol. 2022 Apr 13:100706.

2022 Conboy CB, Penrice DD, Watkins R, Díaz LA, Arab JP, Ilyas SI. Hepatology highlights. Hepatology. 2022 May;75(5):1071-1072.

2022 Kulkarni AV, Kumar K, Candia R, Arab JP, Tevethia HV, Premkumar M, Sharma M, Menon B, Rao GV, Reddy ND, Rao NP. Prophylactic Perioperative Terlipressin Therapy for Preventing Acute Kidney Injury in Living Donor Liver Transplant Recipients: A Systematic Review and Meta-Analysis. J Clin Exp Hepatol. 2022 Mar-Apr;12(2):417-427.

2022 Singal AK, DiMartini A, Leggio L, Arab JP, Kuo YF, Shah VH. Identifying Alcohol Use Disorder in Patients With Cirrhosis Reduces 30-Days Readmission Rate. Alcohol Alcohol. 2022 May 11:agac015.

2022 Alva-Ruiz R, Wu T, Idalsoaga F, Ramkissoon R, Arab JP, Ilyas SI. Hepatology highlights. Hepatology. 2022 Jun;75(6):1363-1364.

2022 El-Kassas M, Cabezas J, Iruzubieta P, Zheng MH, Arab JP, Awad A. Non-alcoholic Fatty Liver Disease: Current Global Burden. Semin Liver Dis. 2022 May 26. doi: 10.1055/a-1862-9088.

2022 Kulkarni AV, Premkumar M, Arab JP, Kumar K, Sharma M, Reddy N, Padaki NR, Reddy R. Early diagnosis and prevention of infections in cirrhosis. Semin Liver Dis. 2022 Jun 7. doi: 10.1055/a-1869-7607.

2022 Povero D, Ahn JC, Arnold J, Udompap P, Ilyas SI, Arab JP. Hepatology Highlights. Hepatology. 2022 Jul;76(1):1-2.

2022 Díaz LA, Ayares G, Arnold J, Idalsoaga F, Corsi O, Arrese M, Arab JP. Liver Diseases in Latin America: Current Status, Unmet Needs, and Opportunities for Improvement. Curr Treat Options Gastroenterol. 2022 Jun 16:1-18.

2022 Singal AK, Kuo YF, Arab JP, Bataller R. Racial and Health Disparities among Cirrhosis-related Hospitalizations in the USA. J Clin Transl Hepatol. 2022 Jun 28;10(3):398-404.

2022 Penrice DD, Tomlinson J, Watkins R, Ayares G, Arab JP, Ilyas SI. Hepatology Highlights. Hepatology. 2022 Aug;76(2):287-288.

2022 Alva-Ruiz R, Ahn JC, Udompap P, Díaz LA, Arab JP. Hepatology highlights. Hepatology. 2022 Sep;76(3):539-540.

2022 Wu T, Povero D, Parthasarathy G, Idalsoaga F, Arab JP, Ilyas SI. Hepatology highlights. Hepatology. 2022 Oct;76(4):901-902.

2022 Ayares G, Idalsoaga F, Díaz LA, Arnold J, Arab JP. Current Medical Treatment for Alcohol-Associated Liver Disease. J Clin Exp Hepatol. 2022 Sep-Oct;12(5):1333-1348.

2022 Vuyyuru SK, Brahmania M, Arab JP, Jairath V. Biologics Are Effective in the Management of Inflammatory Bowel Disease Following Liver Transplantation in Combination With Antirejection Therapy. Inflamm Bowel Dis. 2022 Sep 29:izac207.

2022 Dib M, Le Corre N, Ortiz C, García D, Ferrés M, Martinez-Valdebenito C, Ruiz-Tagle C, Ojeda MJ, Espinoza MA, Jara A, Arab JP, Rabagliati R, Vizcaya C, Ceballos ME, Sarmiento M, Mondaca S, Viñuela M, Pastore A, Szwarcfiter V, Galdames E, Barrera A, Castro P, Gálvez NM, Soto JA, Bueno SM, Kalergis AM, Nervi B, Balcells ME. SARS-CoV-2 vaccine booster in solid organ transplant recipients previously immunised with inactivated versus mRNA vaccines: A prospective cohort study. Lancet Reg Health Am. 2022 Dec;16:100371.

2022 Garcia D, Riveros S, Ochoa G, Rebolledo P, Achurra P, Briceño E, Viñuela E, Arab JP, Jarufe N, Fernandes E, Martinez J, Dib M. Right Lobe Liver Donation After Bariatric Surgery. A Case Series of 4 Living Donors. Transplantation Proceedings, 2022, https://doi.org/10.1016/j.transproceed.2022.08.032. 

2012 Arrese M, Arab JP, Arancibia JP, Candia R, Riquelme A and Barrera F. Liver Disease: A Neglected Complication of Diabetes Mellitus. In: Bagchi D and Sreejayan N, editors. Nutritional and Therapeutic Interventions of Diabetes and Metabolic Syndrome. San Diego: Elsevier/Academic Press. 2012. p. 289–296.

2012 Arab JP, Glasinovic E and Arrese M. Cholestasis: Pathophysiology and Treatment. In: Tagle Arróspide M and Bussalleu Rivera A, editors. Advances in Hepatology 2012 (Avances en Hepatología 2012). Lima: Imp. Santa Ana SAC. 2012. First edition. p. 125-141. (Book in Spanish)

2013 Arab JP and Arrese M. Cholestasis. In: Berger Z, Silva G, Sabah S and Weitz JC, editors. Diagnosis and Treatment of Digestive Diseases. Chilean Society of Gastroenterology. Santiago: Ed. Iku. Third Edition. 2013. p. 287-294. (Book in Spanish)

2015 Arab JP, Arrese M. Hígado graso no alcohólico en paciente no obeso y no diabético. En: Tagle Arróspide M y Bussalleu Rivera A, editores. Escenarios clínicos y controversias en Hepatología 2015. Lima: Tarea Asociación Gráfica Educativa. 2015. Primera edición. p. 141-147 (Book in Spanish).

2015 Ruiz A, Arab JP, Arrese M. Colestasis inducida por fármacos: mecanismos y aproximación clínica. En: Mendez-Sanchez N, editor. HEPATOLOGÍA. Conceptos Básicos y Clínicos. Ciudad de México: McGraw Hill. p.108-117 (Book in Spanish).

2015 Arab JP, Gana JC and Arrese M. Pediatric Non-alcoholic Liver Disease. In: Harris P, Hodgson MI and Gana JC, editors. Clinical Practice in Pediatric Gastroenterology, Hepatology and Nutrition. Santiago: Ed. Universitaria, 2015. First edition. p. 523-530. (Book in Spanish)

2016 Arab JP and Álvarez-Lobos M. Diarrhea in the critically ill. In: Bugedo G and Castillo L. Intensive Care Medicine. Pathophysiology and Clinical Practice. Santiago: Ed. Mediterráneo. Second Edition. p. 480-486. (Book in Spanish)

2016 Tejos R, Arab JP, Arrese M. Cirrhosis. In: Riquelme A, Arrese M, Espino A, Ivanovic-Zuvic D and Latorre G, editors. Manual de Gastroenterología Clínica. Santiago. Ed. Escuela de Medicina, Pontificia Universidad Católica de Chile. Second Edition. 2016. p. 253-259. (Book in Spanish)

2016 Ortiz J, Arab JP, Arrese M. Non-alcoholic fatty liver disease. In: Riquelme A, Arrese M, Espino A, Ivanovic-Zuvic D and Latorre G, editors. Manual de Gastroenterología Clínica. Santiago. Ed. Escuela de Medicina, Pontificia Universidad Católica de Chile. Second Edition. 2016. p. 305-312. (Book in Spanish)

2019 Cabrera D, Arab JP, and Arrese M. UDCA, NorUDCA, and TUDCA in Liver Diseases: A Review of Their Mechanisms of Action and Clinical Applications. Fiorucci S and Distrutti E, eds. Bile acids and their receptors, Handbook of Experimental Pharmacology series. 2019.

2020 Benítez C, Arab JP, Barrera F, Bañales JM, Arrese M. Integrative Proposal for the Use of Biomarkers in Clinical Practice Management of NAFLD/NASH. In: Romero-Gomez M. (eds) NAFLD and NASH. Springer, Cham.

2021 Arab JP, Atkinson S, Bataller R. Alcohol-related Liver Disease. In: Yamada' s Textbook of Gastroenterology, Wiley (in press).

2021 Dirchwolf M, Arab JP, Gadano A, Arrese M. Chapter: Hígado graso no alcohólico: Consideraciones sobre factores de riesgo de evolución a cirrosis y evaluación no invasiva de la fibrosis hepatica. In: Alejandro Bussalleu and Martín Tagle, editors. HEPATOLOGÍA 2020: Aprendizaje basado en Casos Clínicos.

2022 Cyriac Abby Philips, Juan Pablo Arab, Xingshun Qi, Norihiro Imai, and Philip Augustine. Chapter: 'Gut microbiota - Clinical events and therapeutic interventions in alcohol-related liver disease'. In book 'Human Microbiome: Clinical implications and therapeutic interventions' edited by Prof Sabu Thomas, published by Springer Nature (Singapore). https://link.springer.com/book/10.1007/978-981-16-7672-7