Schulich school of Medicine and Dentistry logo Anesthesia and Perioperative Medicine Schulich School of Medicine & Dentistry

Areas of Research

surgical lamp

Acute Pain & Regional

Faculty Profiles: Jon Brookes, Shalini Dhir, Su Ganapathy, Indu Singh, Geoff Bellingham, Kevin Armstrong


Dhir S, Ganapathy S. Success rate of infra-glavicular blocks - comparison of ultrasound vs. neurostimulation guided catheter placement.

  • Academic Medical Org​anization of Southwestern Ontario (AMOSO) Opportunities Fund. 2009-2010: $32,500.
  • Physicians Services Inc. Foundation. 2010-2011: $60,000. Peer-Reviewed.

Dhir S, Tureanu L, Bouzari A, Masood A, Francispragasam M, Ganapathy S. Reduction in sodium content of local anesthetics for peripheral nerve blocks: a comparative evaluation of saline with 5% dextrose--a randomized controlled double-blind study. Anesth Analg. 2012 Jun;114(6):1359-64. Epub 2012 Mar 30

Ponde V, Dhir S. Ultrasound guided sciatic nerve block in infants and toddlers produces successful anesthesia regardless of the motor response. Pediatric Anesthesia 2010;20 (7):663-7.

Ganapathy S, Brookes J, Bourne R. Local Infiltration Analgesia. Anesthesiol Clin. 2011 Jun;29(2):329-42.

Ganapathy S, Chan V (issue editors). Regional Analgesia and Acute Pain Management: Major leaps in small steps? [preface]. Anesthesiol Clin. 2011 Jun;29(2):xii-xiv.

The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON

  • Opioid Tolerance and Pain. Presented by: Dr. Geoff Bellingham
  • Ultrasound-guided Regional Anesthesia – Basic – Lower Limb [Workshop]. Instructed by: Dr. Kevin Armstrong and Dr. Jonathan Brookes (Clinical Fellow)
  • Ultrasound-guided Regional Anesthesia – Basic – Upper Limb [Workshop]. Instructed by: Dr. Indu Singh
  • Ultrasound-guided Regional Anesthesia – Advanced – Torso [Workshop]. Instructed by: Dr. Shalini Dhir
  • Ultrasound and Regional Anesthesia. Presented by: Dr. Su Ganapathy

Airway Management

Faculty Profiles: Kevin Armstrong, Phil Jones, Tim Turkstra, Chris Harle, Ronit Lavi


Jones PM, Turkstra TP, Armstrong KP, Armstrong PM, Harle CC. Comparison of a single-use GlideScope Cobalt videolaryngoscope with a conventional GlideScope for orotracheal intubation. Can J Anaesth 2010;57:18-23.

Jones PM, Loh FL, Youssef HN, Turkstra TP. A randomized comparison of the GlideRite® Rigid Stylet to a malleable stylet for orotracheal intubation by novices using the GlideScope®. Can J Anesth. 2011;58:256-61.

Lavi R, Segal D, Ziser A. Predicting difficult airways using the intubation difficulty scale: a study comparing obese and non-obese patients. J Clinical Anesth. 2009 Jun;21(4):264-7.

Turkstra TP, Pelz DM, Jones PM. Cervical spine motion: a fluoroscopic comparison of the AirTraq Laryngoscope versus the Macintosh laryngoscope. Anesthesiology. 2009;111(1):97-101.

Ambulatory

Faculty Profiles: Achal Dhir, Ian McConachie, Chris Harle


The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON.

  • Anesthetic Management of Iatrogenic Tracheal Rupture. Presented by: Dr. Joanne Dion. Coauthor: Dr. Achal Dhir
  • Oh Sweet Mystery of Life: Diabetes Management in Ambulatory Patients. Presented by: Dr. Ian McConachie
  • Colonoscopy: Working Where the Sun Don’t Shine. Presented by: Dr. Chris Harle

Cardiac

Faculty Profiles: Daniel Bainbridge, Davy Cheng, Ronit Lavi, Janet Martin, John Murkin, Ravi Taneja, Phil Jones, Chris Harle, Wojceich Dobkowski, Miguel Arango


Bainbridge D, Cheng D. Stress-induced cardiomyopathy in the perioperative setting. Canadian Journal of Anesthesia. 2009 Jun;56(6):397-401.

Bainbridge D, Martin J, Arango M, Cheng D; Evidence-based Peri-operative Clinical Outcomes Research (EPiCOR) Group. Perioperative and anaesthetic-related mortality in developed and developing countries: a systematic review and meta-analysis. Lancet. 2012 Sep 22;380(9847):1075-81.

Cheng D. Sugammadex use in patients with history of pulmonary disease. J Clin Anesth. 2012 Jun;24(4):289-97.

Cheng D, Martin J, Dunning J, Shennib H, Muneretto C, Schueler S, et al. Endovascular aoritc repair versus open surgical repair for descending thoracic aortic disease: a systematic review and meta-analysis of comparative studies. J Am Coll Cardiol. 2010 Mar 9;55(10):986-1001.

  • This paper is highlighted in TCTMD- the Premier Educational Resource for the Interventional Cardiology and Endovascular Medicine Community. This paper is also featured on The Doctor’s Channel. 

Jones PM, Bainbridge D, Dobkowski W, Harle CC, Murkin JM, et al. Comparison of the MAX-ACT and K-ACT values when using Bivalirudin Anticoagulation During Minimally Invasive Hybrid Off-Pump Coronary Artery Bypass Graft Surgery. J Cardiothorac Vasc Anesth. 2011;25(3):415-8.

Lavi R, Cheng D. Pro: Continuous cardiac output and SvO(2) monitoring should be routine during off-pump coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth. 2012 May 23. [Epub ahead of print]

Lavi S, Lavi R. Conditioning of the heart: from pharmacological interventions to local and remote protection - possible implications for clinical practice. Int J Cardiol. 2011; 146(3):311-8.

Murkin JM. Cerebral autoregulation: the role of CO2 in metabolic homeostasis. Sem Cardiothorac Vasc Anesth. 2007 Dec;11(4):269-73.

Taneja R, Fernandes P, Marwaha G, Cheng D, Bainbridge D. Perioperative coagulation management and blood conservation in cardiac surgery: a Canadian survey. J Cardiothorac Vasc Anesth. 2008 Oct;22(5):662-9.

Chade AR, Zhu X, Lavi R, Krier JD, Pislaru S, Simari RD, et al. Endothelial progenitor cells restore renal function in chronic experimental renovascular disease. Circulation. 2009 Feb 3;119(4):547-57.

CSRU

Faculty Profiles: Mike Sharpe


Gofton TE, Chouinard PA, Young GB, Sharpe MD, et al. Functional MRI study of the primary somatosensory cortex in comatose survivors of cardiac arrest. Experimental Neurology. 2009 June;217(2):320-327.

Young GB, Sharpe MD, et al. Seizure detection with a commercially available bedside EEG monitor and the subhairline montage. Neurocrit Care. 2009 Dec;11(3):411-6.

Chronic Pain Management

Faculty Profiles: Pat Morley-Forster


VanUum S, Chaudhary S, Morley-Forster PK. Chronic opioid therapy: does it affect the endocrine system? Canadian Journal of Diagnosis. 2010;27(3):37-38. 

The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON.

  • Frontiers in Pain Education: The New RCPSC Sub-Specialty, and the American Pain Directors of Canada. Presented by: Dr. Pat Morley-Forster

Evidence Based Medicine

Faculty Profiles: Davy Cheng, Janet Martin, Daniel Bainbridge


Click here for the extensive list of research by the EPiCOR group.

Cheng D, Martin J (Co-Principal Investigators).

  • AHSC AFP Innovation Grant. Evidence Based Decision Making and Health Technology Assessment for Anesthesia and Surgery - Building a Centre of Excellence. 2011-2012: $372,500.
  • AHSC AFP Innovation Grant. Evidence Based Perioperative Drug Therapy: Getting Evidence into Policy and Practice. 2009-2011: $205,000.

Wang G, Bainbridge D, Martin J, Cheng D. N-acetylcysteine in cardiac surgery: Do the benefits outweigh the risks? A meta-analytic reappraisal. J Cardiothor Vasc Anesth 2011;25(2):268-275.

Hall R, Beattie S, Cheng D, Choi P, Denault AY, Mazer D, et al. Can We Develop a Canadian Perioperative Anesthesiology Clinical Trials Group? Can J Anaesth. 2010 Dec;57 (12):1051-57.

Cheng D, Martin J. Evidence-based practice and health technology assessment: a call for anesthesiologists to engage in knowledge translation. Can J Anesth 2011; 58(4):354-63.

Neuroanesthesia

Faculty Profiles: Rosemary Craen, Tim Turkstra


Fabregas N, Craen RA. Anaesthesia for endoscopic neurosurgical procedures. Curr Opin Anaesthesiol. 2010 Oct;23(5):568-75.

The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON.

  • Neuroemergencies in the Recovery Room. Presented by: Dr. Tim Turkstra

Obstetric Anesthesia

Faculty Profiles: Ian Herrick, Tim Turkstra, Phil Jones, Indu Singh


Ioscovich A, Shen O, Sichel JY, Lajos Y, Orkin D, Bromiker R, Briskin A. Remifentanil-nitroglycerin combination as an anesthetic support for ex utero intrapartum treatment (EXIT) procedure. J Clin Anesth. 2011 Mar;23(2):142-4.

Leung LS, Petropoulos S, Shen B, Luo T, Herrick I, et al. Lesion of cholinergic neurons in nucleus basalis enhances response to general anesthetics. Exp Neurol. 2011;228:259-269.

Turkstra TP, Armstrong PM, Jones PM, Quach T. GlideScope use in the obstetric patient. Int J Obstet Anesth. 2010;19:123-4.

The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON

  • Anesthetic Management of a Paturient with Severe Mitral Stenosis: A Case Report and Literature Review. Presented by: Dr. Kristine Marmai, Coauthors: Dr. Indu Singh, and Dr. Thomas Quach
  • Fetal Benefit of Maternal Oxygen Supplementation During Elective Caesarean Section Under Neuroaxial Anesthesia: A Systematic Review. Presented by: Dr. Kristine Marmai, Coauthors: Dr. Indu Singh, and Dr. Phil Jones

Pediatric Anesthesia

Faculty Profiles: Shalini Dhir


Ponde V, Dhir S. Ultrasound guided sciatic nerve block in infants and toddlers produces successful anesthesia regardless of the motor response. Pediatric Anesthesia. 2010; 20(7):663-7.

Perioperative Blood Management

Faculty Profiles: Fiona Ralley, Achal Dhir, Chris Harle


Ralley FE, Berta D, Binns V, Howard J, Naudie DD. One intraoperative dose of transexamic acid for patients having primary hip or knee anthroplasty. Clin Orthop Relat Res. 2010 Jul;468(7):1905-11.

The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON.

  • Coagulations and Hemodynamic Problems Associated with End-Stage Liver Disease. Presented by: Dr. Achal Dhir and Dr. Chris Harle

Pharmacology: Basic Science and Clinical

McAlister V, Burns KE, Znajda T, Church B. Hypertonic saline for perioperative fluid management. Cochrane Database Syst Rev. 2010;(1):CD005576.

Kiviniemi AM, Frances MF, Tiinanen S, Craen R, Rachinsky M, et al. α-Adrenergic effects on low-frequency oscillations in blood pressure and R-R intervals during sympathetic activation. Exp Physiol. 2011 Aug;96(8):718-35. Epub 2011 May 20.

The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON.

  • Intraoperative Stability of Patients with Carcinoid Syndrome Treated with Long-Acting Octreotide. Presented by: Dr. Jon Borger. Coauthors: Dr. Neal Badner, and Dr. Daryl Gray

Simulation

Faculty Profiles: Daniel Bainbridge


Bainbridge D (Co-Investigator), et al. Canadian Foundation for Innovation: Imaging-Guided Minimally Invasive Intervention and Simulation. 2009-2012: $2,577,602.

Thoracic and Vascular

Faculty Profiles: George Nicolaou, Bill Sischek


Tran DTT, Badner NH, Nicolaou G, Sischeck W. Arterial PCO2 changes during thoracoscopic surgery with CO2 insufflation and one lung ventilation. HSR Proceedings in Intensive Care and Cardiovascular Anesthesia. 2010;2(3):191-7.

Nicolaou G, Forbes TL. Strategies for accurate endograft placement in the proximal thoracic aorta. Semin Cardiothorac Vasc Anesth. 2010 Sep;14(3):196-200. Epub 2010 Jul 14.

Transplant

Faculty Profiles: Achal Dhir, Wojciech Dobkowski


The Canadian Anesthesiologists’ Society (CAS) Annual Meeting. 2011 June 24-28; Toronto, ON.

  • Combined Heart and Liver Transplant: Our Experience. Presented by: Dr. Pratyush Gupta (Clinical Fellow). Coauthors: Dr. Achal Dhir, Dr. Wojciech Dobkowski, and Dr. David Sommerfreund
  • Pre-washed PRBCs Prevent Hyperkalemia in Massive Transfusion. Presented by: Dr. Pratyush Gupta (Clinical Fellow). Coauthors: Dr. Achal Dhir