Dr. Constance Mackenzie, MD, MSc, FRCPC

Rank / Affiliations

  • Assistant Professor, Western University
  • Assistant Medical Director Ontario/Manitoba/Nunavut Poison Centre
  • Department of Clinical Pharmacology and Toxicology, The Hospital For Sick Children, Toronto, ON
  • POEM (Program of Experimental Medicine) member, Western University


Cross Appointments

  • Respirology, Western University, London, ON
  • Clinical Pharmacology and Toxicology, Western University, London, ON
  • Clinical Pharmacology and Toxicology, University of Toronto, Toronto, ON
  • The Hospital For Sick Children, Toronto, ON



  • Undergraduate BSc (Hons), Western University
  • MSc, Trent University
  • MD, University of Ottawa
  • Internal Medicine, Western University (FRCPC 2010)
  • Respirology, Western University (FRCPC 2013)
  • Clinical Pharmacology & Toxicology, Western University (FRCPC 2013)


Clinical Interests

  • Occupational lung diseases
  • Asthma
  • Medical toxicology


Research interests

  • Pharmacogenetics of inhaled steroids in asthma
  • Cyclosporine as a novel treatment for amatoxin-containing mushroom poisoning 
  • Vaping-associated lung injury


Recent Publications

Landman ST, Dhaliwal I, Mackenzie CA, Martinu T, Steele A, Bosma KJ. Life-threatening bronchiolitis related to electronic cigarette use in a Canadian youth. CMAJ. 2019;191(48):E1321–E1331. doi:10.1503/cmaj.191402


Austin E, Myron HS, Summerbell RK, Mackenzie C. Acute renal injury cause by confirmed Psilocybe cubensis mushroom ingestion. Med Mycol Case Rep. 2018;23:55–57. doi:10.1016/j.mmcr.2018.12.007


Mackenzie CA. Fool Me Once…Fool Me Twice….The Rise of E-Cigarettes. Update on Respiratory Health, Research and Education, Ontario Respiratory Care Society, The Lung Association, Winter 2020 Issue 10


Contact Information

St. Joseph's Health Care

268 Grosvenor Street

Phone: (519) 646-6000 x66065