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The role of Voluven in cerebral resuscitation

Thursday, January 31, 2013

Recent prospective randomized studies have raised significant concerns regarding the safety of voluven and related synthetic colloid solutions when used as volume expanders in certain high risk groups of patients. This invited editorial by Dr. John Murkin, provides a brief overview of this issue and a further perspective on the usage of such substances in other patient subgroups.

Can J Anaesth. 2012 Dec;59(12):1089-94. doi: 10.1007/s12630-012-9800-y. Epub 2012 Nov 28

"Primum non nocere": the role of hydroxyethyl starch 130/0.4 in cerebral resuscitation.

Murkin JM.

Editor's Note:

"....A particularly controversial topic is the role of hydroxyethyl starchesin traumatic brain injury. In light of the controversy in the literature and findings from recent studies, we offer the following invited editorial perspective by Dr. John Murkin, Professor of Anesthesiology from the Schulich School of Medicine, University of Western Ontario, London, Ontario".
Donald R. Miller, M.D., Editor-in-Chief

View the PubMed Record