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Dr. Cory Yamashita, MD, FRCPC

 

Rank/ Affiliations:

  • Assistant Professor
  • Lawson Health Research Institute (LHRI), Scientist

Training:

  • Undergraduate, University of Manitoba
  • MD, University of Manitoba
  • Internal Medicine, University of Western Ontario
  • Respirology, University of Western Ontario
  • Research Fellowship, Acute Lung Injury, University of Western Ontario
  • Research Fellowship, Lung Injury & Repair, National Jewish Health, Denver, CO

Clinical Interest:

  • General Respirology
  • Asthma

Research Interest:

  • Antimicrobial Peptides/ Pulmonary Surfactant
  • Mechanisms of Acute Lung Injury and Multiple Organ Failure
  • The Role of MMP-3 in Acute Lung Injury
  • Ventilator Induced Lung Injury

Research Funding:

  • PSI Foundation
  • Ontario Thoracic Society
  • Lawson Health Research Institute
  • University of Western Ontario
  • UWO Department of Medicine, Program of Experimental Medicine

Awards:

  • Parker B. Francis Foundation Fellowship (2009-2012)
  • Honour Roll Certificate, University Students’ Council, The University of Western            Ontario Excellence in Teaching Undergraduate Medical Education, 2011-12
  • Honour Roll Certificate, University Students' Council, Undergraduate, Department of Physiology & Pharmacology, 2012

Selected Publications:

  • Yamashita CM, Radisky DC, Yael Aschner Y and Downey GP.  The Importance of MMP3 in Respiratory Disorders.  Expert Review in Respiratory Medicine 2014 (In press)
  • Radhakrishnan, D, Yamashita, CM, Gillio-Meina, C, Fraser DD.  Translational Research in Pediatrics III: Flexible Bronchoscopy and Bronchoalveolar Lavage.  Pediatrics 2014 (In press)
  • Yamashita CM, Fessler MB, Vasanthamohan L, Lac J, Madenspacher J, McCaig L, Yao LJ, Wang LF, Mehta S, Lewis JF and Veldhuizen RAW.  Apolipoprotein E Deficient Mice are Susceptible to the Development of Acute Lung Injury.  Respiration 2014; March 22 [Epub ahead of print]
  • Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP.  Protein Tyrosine Phosphatase-α Mediates Pro-Fibrotic Signaling in Lung Fibroblasts through TGF-β Responsiveness.  Am J Pathol 2014; March 17 [Epub ahead of print]
  • Gill SE, Veldhuizen RAW, Yamashita CM.  Alveolar Macrophages and Pulmonary Surfactant - More Than Just Friendly Neighbors.  OA Biology 2013; Dec01;1(1):6
  • Skeith L, Yamashita C, Mehta S, Farquhar D, Kim RB. Sildenafil and Furosemide Associated Ototoxicity: Considerations of Drug-drug Interactions, Synergy, and Broader Clinical Implications.  J Popul Ther Clin Pharmacol 2013;20(2):128-31
  • EK Patterson, LJ Yao, JF Lewis, G Cepinskas, L McCaig, RAW Veldhuizen and CM Yamashita. Lung Derived Mediators Induce Cytokine Production in Downstream Organs via an NF-κB Dependent Mechanism. Mediators Inflamm 2013;2013/586895
  • Yamashita CM, Lewis JF.  Emerging Therapies for Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome.  Expert Opin Emerg Drugs 2012;17(1):1-4
  • Schmidt EP, Lee WL, Zemans RL, Yamashita CM, Downey GP.  On, Around and Through: Neutrophil-Endothelial Interactions in Innate Immunity.  Physiology 2011;26(5):334-347
  • Yamashita CM, Dolgonos L, Young S, Robertson J, Briones N, Suzuki T, Gauldie J, Radisky D, Yu G, Kaminski N, Laschinger C, McCulloch C, Downey GP.  Matrix Metalloproteinase-3 is a Mediator of Pulmonary Fibrosis.  Am J Pathol 2011;179(4):1733-45
  • Walker MG, Yao L, Patterson E, Joseph M, Cepinskas G, Veldhuizen RA, Lewis J, Yamashita CM.  The Effect of Tidal Volume on Systemic Inflammation in Acid-Induced Lung Injury.  Respiration 2011;81(4):333-42
  • Yamashita CM, Veldhuizen RA.  Swept Under the Carpet?  The Role of Mucocilliary Clearance in Ventilator-Induced Lung Injury.  Intensive Care Med 2011;37(1):4-6
  • Yamashita CM, Langridge J, Hergott C, Malthaner R, Inculet R, Mahon J, Mehta S, Lefcoe M, McCormack D.  Predicting Postoperative FEV1 Using Spiral Computed Tomography to Measure Regional Perfused Blood Volume.  Acad Radiol 2010; 17(5):607-613
  • Suzuki T, Yamashita CM, Zemans R, Briones N, Van Linden A, Downey GP.  Leukocyte Elastase Induces Lung Epithelial Apoptosis via a PAR-1, NF-kB, and P53-dependent Pathway. Am J Respir Cell Mol Biol 2009 41(6):742-755
  • Yamashita CM, Lynch D, Downey GP.  Lymphangioleiomyomatosis.  Clin Pul Med 2008;15(6):325-331
  • Yamashita CM, Forbes A, Tessolini JM, Yao LJ, Lewis JF, Veldhuizen RA. Protective effects of elevated endogenous surfactant pools to injurious mechanical ventilation.  Am J Physiol Lung Cell Mol Physiol  2008;294:L724-32

Contact Information:

 

St. Joseph's Health Centre

          Room E5-120, 268 Grosvenor St.

          Phone: (519) 646-6000, x65283

          Administrative Assistant: Cathy Ede


 

 

 

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