Dr. Tom Sheidow
Dr. Tom Sheidow, MD, MMath, BEd, BMath, FRCS(C), DRCSC
Ivey Eye Institute
St. Joseph's Hospital
268 Grosvenor Street
London, Ontario N6A 4V2
Phone: 519.646.6100 ext. 58133
Fax: 519.646.6355
Specialty: Vitreo Retinal Surgery
Clinical Focus: Macular Degeneration, Adult Surgical Retinal Disorders, Macular Diseases
Residency: Western University
Fellowship (Institution):
Vitreo Retinal Surgery,
Barnes Retina Institute, St. Louis, Missouri
Appointment:
Associate Professor of Ophthalmology
Ivey Eye Institute
Western University
Publications
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1. Kos, A. Burszyn, L. Sheidow, TG. Focal retinal venous occlusion in Susac Syndrome. Journal of Neuro-Ophthalmology. 2025; 45: e290-292.
2. Zajner C, Leung B, Sheidow T, and Malvankar-Mehta MS. Quality of Life after Pars Plana Vitrectomy, Scleral Buckle, or Pneumatic Retinopexy for Rhegmatogenous Retinal Detachment: A Meta-Analysis. Current Eye Research, 49(3), 295-302, DOI: 10.1080/02713683.2023.2280440
3. Khanani A.M., Kotecha A., Chang A., Chen S.-J., Chen Y., Guymer R. et al TENAYA and LUCERNE: Two-Year Results from the Phase 3 Neovascular Age-Related Macular Degeneration Trials of Faricimab with Treat-and-Extend Dosing in Year 2Ophthalmology, DOI: 10.1016/j.ophtha.2024.02.014
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85187901367&doi=10.1016%2fj.ophtha.2024.02.014&partnerID=40&md5=35e241e53cee38b06f066fcc296b23704. Basilious A., Duncan J., Smuck B., Malvankar-Mehta, M.S. Juncal V., Hooper P., Sheidow T., Patterns of anti-vascular endothelial growth factor discontinuation in neovascular age-related macular degeneration. Canadian Journal of Ophthalmology, 59(2), e161-e169, 2024.
5. Tien Y. Wong, Zdenka Haskova, Kemal Asik, Caroline R. Baumal, Karl G. Csaky, et al. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials, Ophthalmology, 2023, https://doi.org/10.1016/j.ophtha.2023.12.026.
6. Jeffrey S Heier, Eleonora M Lad, Frank G Holz, Philip J Rosenfeld, Robyn H Guymer et al. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials, The Lancet, Volume 402, Issue 10411, 2023, Pages 1434-1448,https://doi.org/10.1016/S0140-6736(23)01520-9.
7. Basilious, Smuck, B., Duncan, J., Malvankar-Mehta, M. S., Juncal, V. R., Hooper, P., & Sheidow, T. G.. Treatment discontinuation patterns of anti VEGF in retinal vein occlusion. Canadian Journal of Ophthalmology. Canadian Journal of Ophthalmology. 59(5), 341-349, 2024
8. Popovic MM; Sheidow T; Baker J; Kertes PJ. Maximal Extension Interval and Visual Outcomes in a Treat-and-Extend Protocol: A Post Hoc Analysis of the CANTREAT Randomized Trial. Ophthalmologica. 246(2):123-130, 2023.
9. Son M, Bessemer R, Vinokurtseva A, Gostimir M, Sheidow T, Morrow SA. Herpes Simplex 2 Encephalitis and Acute Retinal Necrosis. Can J Neurol Sci. 51(2), 320-322, 2024.
10. Cheung R, Chun J, Sheidow T, Motolko M, Malvankar-Mehta MS. Diagnostic accuracy of current machine learning classifiers for age-related macular degeneration: a systematic review and meta-analysis. Eye. 2022;36(5):994-1004. doi:10.1038/s41433-021-01540-y, 10.1038/s41433-021-01540-y
11. Betsch, DM, Gupta, RR, for the Dexamethasone Intravitreal Implant Migration Study Group. Management and Complications of Dexamethasone Intravitreal Implant Migration Into the Anterior Chamber. Journal of VitreoRetinal Diseases 2022, Vol. 6(6) 432–436
12. Kertes PJ, Sheidow T, Williams G, Greve M, Galic IJ, Baker J. Long-term Efficacy of a Treat-and-Extend Regimen With Ranibizumab in Patients With Neovascular Age-Related Macular Disease: An Open-label 12-month Extension to the CANTREAT Study. Ophthalmologica. 2021 Dec 30.
13. Foster LD, McDonald HM, Sheidow TG. Was it Leuconostoc species? A case of delayed-onset endophthalmitis presenting 14 years after cataract surgery. RETINAL Cases & Brief Reports. 17(4), 410-413, 2023.
14. Nanji, K. Sarohia, GS., Kennedy, K., Ceyhan,T., McKechnie, T., Phillips, M., Devji, T., Thabane, L., Kaiser, P., Sarraf, D., Garg, SJ., Sivaprasad, S., Wykoff, CC., Bakri, SJ., Sheidow, T., Bhandari, M., Chaudhary,V. The 12- and 24-Month Effects of Intravitreal Ranibizumab, Aflibercept, and Bevacizumab on Intraocular Pressure: A Network Meta-Analysis, Ophthalmology, 129(5), 498-50, 2021. https://doi.org/10.1016/j.ophtha.2021.11.024.
15. Wong DT, Berger AR, Bourgault S, Chen J, Colleaux K, Cruess AF, Dookeran RI, Gauthier D, Hurley B, Kapusta MA, Kertes PJ, Qian CX, Samad A, Sheidow T, Whelan JH. Imaging Biomarkers and Their Impact on Therapeutic Decision Making in the Management of Neovascular Age-related Macular Degeneration. [Review]. Ophthalmologica 2021; Vol 244(4):265-280.
16. Cheung, R., Chun J., Sheidow, T., Motolko, M., and Malvankar-Mehta., M. Diagnostic Accuracy of Current Machine Learning Classifiers for Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis. Eye 36(5), 994-1004, 2021.
17. Schulz, DC., Orr, SM., Johnstone, R, Devlin, MK., Sheidow, TG., Bursztyn, LLCD. The many faces of ocular syphilis: case-based update on recognition, diagnosis, and treatment. Canadian Journal of Ophthalmology, Vol 56 (5), 2021.
18. Ballios, BG., Park, T., Chaudhary, V., Hurley, B., Kosar, S., Sheidow, T., Cruess, A., Brent, M.H., Glazier, R., Wong, D.T. Identifying gaps in patient access to diabetic screening eye examinations in Ontario: a provincially representative cross-sectional study. Canadian Journal of Ophthalmology, 2020, Nov 21.
19. Yu BE; Sheidow T; Sambhi RS; Hooper P; Malvankar-Mehta MS. The effectiveness of ocriplasmin versus surgery for the treatment of macular holes: A systematic review and meta-analysis. European Journal of Ophthalmology. 2020 Jul 30.
20. Boucher MC; Qian J; Brent MH; Wong DT; Sheidow T; Duval R; Kherani A; Dookeran R; Maberley D; Samad A; Chaudhary V; Steering Committee for Tele-Ophthalmology Screening, Canadian Retina Research Network. Evidence-based Canadian guidelines for tele-retina screening for diabetic retinopathy: recommendations from the Canadian Retina Research Network (CR2N) Tele-Retina Steering Committee. Canadian Journal of Ophthalmology. 55(1 Suppl 1):14-24, 2020.
21. Denstedt J; Schulz DC; Diaconita V; Sheidow TG. Acupuncture resulting in eye penetration and proliferative vitreoretinopathy - Surgical and medical management with intraocular methotrexate. American Journal of Ophthalmology Case Reports. 18:100605, 2020 Jun.
22. Mitchell P, Sheidow TG, Farah ME, Mahmood S, Minnella AM, Eter N, et al. (2020) Effectiveness and safety of ranibizumab 0.5 mg in treatment-naïve patients with diabetic macular edema: Results from the real-world global LUMINOUS study. PLoS ONE 15(6): e0233595. June 3, 2020. https://doi.org/10.1371/journal.pone.0233595
23. Kertes PJ; Galic IJ; Greve M; Williams G; Baker J; Lahaie M; Sheidow T. Efficacy of a Treat-and-Extend Regimen With Ranibizumab in Patients With Neovascular Age-Related Macular Disease: A Randomized Clinical Trial. JAMA Ophthalmology. 138(3):244-250, 2020 Mar 01.
24. Boucher, MC, Brent, MH; Wong , DT; Sheidow, T; Duval, R; Kherani, A; Dookeran, R; Maberley, D; Samad, A; Chaudhary, V. Evidence-based Canadian guidelines for tele-retina screening for diabetic retinopathy: recommendations from the Canadian Retina Research Network (CR2N) Tele-Retina Steering Committee. Canadian Journal of Ophthalmology. Volume 55, Issue 1, Supplement 1, February 2020, Pages 14-24
25. Filek, R; Hooper, PL; Sheidow, TG; Hong, H; Chakrabarti, S; Hutnik, CML. Safety of anti-VEGF treatments in a diabetic rat model and retinal cell culture. Clinical Ophthalmology 2019, Vol.13, p.1097-1114
26. Pike D; Mandelcorn ED; Sheidow T; Whelan JH. Inner-limiting-membrane peeling in epiretinal membrane surgery: an evolving surgical trend. Canadian Journal of Ophthalmology. 2019 Sep 14.
27. Filek, R; Hooper, PL; Sheidow, TG; Gonder, J; Chakrabarti, S; Hutnik, CML. Two-year analysis of changes in the optic nerve and retina following anti-VEGF treatments in diabetic macular edema patients. Clinical Ophthalmology 2019:13 1087–1096.
28. Gupta, R; Sheidow, T. Bilateral serous retinal detachment in association with preeclampsia. Canadian Journal of Ophthalmology/Journal canadien d'ophtalmologie, June 2019, Vol.54(3), pp.e98-e100
29. Kertes PJ; Galic IJ; Greve M; Williams RG; Rampakakis E; Scarino A; Sheidow T. Canadian Treat-and-Extend Analysis Trial with Ranibizumab in Patients with Neovascular Age-Related Macular Disease: One-Year Results of the Randomized Canadian Treat-and-Extend Analysis Trial with Ranibizumab Study. Ophthalmology. 2019, 126(6): 841-848.
30. Filek, R; Hooper, P; Sheidow, T; Gonder, J; Varma, D K; Heckler, L; Hodge, W; Chakrabarti, S; Hutnik, C M L. Structural and functional changes to the retina and optic nerve following panretinal photocoagulation over a 2-year time period. Eye. 31(8):1237-1244, 2017 Aug.
31. Devenyi, Robert; Maberley, David; Sheidow, Tom G; Tourville, Eric; Brunck, Lynne; Berger, Alan R. Real-world utilization of ranibizumab in wet age-related macular degeneration patients from Canada. Canadian Journal of Ophthalmology. 51(2):55-7, 2016 Apr.
32. Li, Bo, Allen, Larry H, Hooper, Sheidow, Thomas G. Vision loss and vascular compromise with facial and periocular injections. Canadian Journal of Ophthalmology. 50(4): e57-e60, 2015 Aug.
33. Chen YN, Powell, Anne-Marie, Sheidow, Mao, A, Sheidow Tom G. Retrospective review of lucentis “Treat andEextend”patterns and outcomes in age-related macular degeneration A Randomized Clinical Trial. Retina 36(2): 272-8, 2015.
34. Rayat J, Rudnisky C, Waite C, Huang P, Sheidow T, Kherani A, Tennant M. Long-term outcomes for optic disk pit maculopathy after vitrectomy. Retina. 2015; 35(10):2011-2017.
35. Lam, Wai-Ching; Albiani, David A; Yoganathan, Pradeepa; Chen, John Chanchiang; Kherani, Amin; Maberley, David Al; Oliver, Alejandro; Rabinovitch, Theodore; Sheidow, Thomas G; Tourville, Eric; Wittenberg, Leah A; Sigouin, Chris; Baptiste, Darryl C. Real-world assessment of intravitreal dexamethasone implant (0.7 mg) in patients with macular edema: the ChrOMe study. Clinical Ophthalmology 2015: 10; 9: 1255–1268.
36. Berger A; Sheidow T; Cruess AF; Arbour JD; Courseau AS; de Takacsy F. Efficacy/safety of ranibizumab monotherapy or with laser versus laser monotherpay in DME. Canadian Journal of Ophthalmology. 50(3):209-16, 2015 Jun.
37. Li, Bo, Powell, Anne-Marie, Hooper, Philip L. Sheidow, Thomas G. Prospective Evaluation of Teleophthalmology in Screening and Recurrence Monitoring of Neovascular Age-Related Macular Degeneration. A Randomized Clinical Trial. JAMA Ophthalmol Dec 4, 2014.
38. Golesic, Elizabeth A. MD; Sheidow, Tom G. An otherwise healthy young man presents with bilateral CRVO as the first sign of hyperviscosity syndrome in the setting of new multiple myeloma. Retinal Cases & Brief Reports. 9(1):38-40, 2015.
39. Bursztyn LL. Masri M. Sheidow TG. Severe visual loss secondary to retinal toxicity after intravenous use of bisphosphonate in an eye with known chloroquine maculopathy. RETINAL Cases & Brief Reports. 8(4): 322-5, 2014.
40. Iordanous, Yiannis MD; Sheidow, Tom G. Late retinal neovascularization after central retinal vein occlusion: a case report and literature review “. Retinal Cases & Brief Reports. 8(3), 230–234, 2014.
41. Iordanous Y, Powell AM, Mao A, Hooper PL, Eng KT, Schwartz C, Kertes PJ, SheidowTG. Intravitreal ranibizumabforthetreatmentof fibrovascular pigment epithelial detachment in age-relatedmacular degeneration. Canadian Journal of Ophthalmology. 2014 49(4), 367-376.
42. Holz FG. Bandello F. Gillies M. Mitchell P. Osborne A. Sheidow T. Souied E. Figueroa MS. LUMINOUS Steering Committee. Safety of ranibizumab in routine clinical practice: 1-year retrospective pooled analysis of four European neovascular AMD registries within the LUMINOUS programme. British Journal of Ophthalmology. 97(9): 1161-7, 2013 Sep.
43. Iordanous Y. Sheidow TG. Vitrectomy for X-linked retinoschisis: a case report and literature review. Canadian Journal of Ophthalmology. 2013 48(4):e71-4.
44. Gill K, Mao A, Powell AM, Sheidow T. Digital reader vs print media: the role of digital technology in reading accuracy in age-related macular degeneration. Eye (2013) 27, 639–643.
45. Cruess AF, Berger, A, Colleaux K, Greve M, Harvey P, Kertes PJ, Sheidow T, Tourville E, Williams G, Wong D. Canadian expert consensus: optimal treatment of neovascular age-related macular degeneration. Canadian Journal of Ophthalmology 2012;47:227–235.
46. Kent JS, Iordanous Y, Mao A, Powell AM, Shukla Kent S,. Sheidow TG. Comparison of outcomes after switching treatment from intravitreal bevacizumab to ranibizumab in neovascular age-related macular degeneration Canadian Journal of Ophthalmology. 47(2): 159-164, 2012 April.
47. Baryla J, Allen LH, Kwan K, Ong T, Sheidow T. Choroidal lymphoma with orbital and optic nerve extension: case and review of literature. Canadian Journal of Ophthalmology. 47(1): 9-80, 2012 Feb.
48. Yau GL. Jackman CS. Hooper PL. Sheidow TG. Intravitreal injection anesthesia--comparison of different topical agents: a prospective randomized controlled trial. American Journal of Ophthalmology. 151(2):333-7. 2011 Feb.
49. Robitaille Johane M, Zheng Binyou, Wallace Karin, Beis M Jill, Tatlidil Cuneyt, Yang Jenny, Sheidow Tom G, Siebert Lee, Levin Alex V, Lam Wai-Ching, Arthur Brian W, Lyons Christopher J, Jaakkola Elisa, Tsilou Ekaterini, Williams Charles A, Weaver Richard Grey, Jr, Shields Carol L, Guernsey Duane L. The role of Frizzled-4 mutations in familial exudative vitreoretinopathy and Coats disease. British Journal of Ophthalmology. 95(4):574-9, 2011 Apr.
50. Wan Michael J, Hooper Phil L, Sheidow Tom G. Combination therapy in exudative age-related macular degeneration: visual outcomes following combined treatment with photodynamic therapy and intravitreal bevacizumab Canadian Journal of Ophthalmology 2010, 45(4), p. 375-380.
51. Ells A, Guernsey DL, Wallace K, Zheng B, Vincer M, Allen A, Ingram A, Dasilva O, Siebert L, Sheidow T, Beis J, Robitaille JM. Severe retinopathy of prematurity associated with FZD4 mutations. Ophthalmic Genet. 2010 Mar;31(1):37-43.
52. Maberley D. Canadian Retinal Trials Group. Photodynamic Therapy and Intravitreal Triamcinolone for Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial. Ophthalmology (November 2009), 116 (11), pg. 2149-2157.
53. Kaiser PK. Registry of Visudyne AMD Therapy Writing Committee. Boyer DS. Garcia R. Hao Y. Hughes MS. Jabbour NM. Kaiser PK. Mieler W. Slakter JS. Samuel M. Tolentino MJ. Roth D. Sheidow T. Strong HA. Verteporfin photodynamic therapy combined with intravitreal bevacizumab for neovascular age-related macular degeneration. Ophthalmology. 116(4):747-55, 755.e1, 2009 Apr.
54. Wan, M, Sheidow T Heathcote JG. Vitritis as the initial manifestation of recurrent mycosis fungoides. Retinal Cases and Brief Reports 3(3): 240-242, Summer 2009.
55. Wan, M and Sheidow T. Macular hole secondary to a subretinal hemorrhage. Retinal Cases and Brief Reports 3(1): 86-88, Winter 2009.
56. Moosbrugger KA, Sheidow TG. Evaluation of the side effects and image quality during digital fluorescein angiography comparing 2ml versus 5ml sodium fluorescein. Can J Ophthalmol 2008 43(5): 571-575.
57. Chaudhary V, Sheidow TG, Mao A, Hooper PL. The effect of triamcinolone acetonide as an adjunctive treatment to verteporfin therapy in neovascular age-related macular degeneration: a prospective, randomized, placebo controlled pilot clinical trial. Ophthalmolgy 2007; 114(6): 2183-2189.
58. heidow TG. Review of Comparison of the Modified Early Treatment Diabetic Retinopathy Study and Mild Macular Grid Laser Photocoagulation Strategies for Diabetic Macular Edema. Evidence Based Ophthalmology 2007; 8(4): 205-207.
59. Proulx AA, Sheidow TG. Development of macular hole in the immediate postoperative period following pneumatic retinopexy. Ophthalmic Surg Lasers Imaging 2006;37: 481-483.
60. Pirbhai A, Sheidow TG, Hooper PL. Prospective Evaluation of Digital Non-Stereo Colour Fundus Photography as a Screening Tool in Age-Related Macular Degeneration. AJO 2005; 139(3): 455-461.
61. Sheidow TG, Sexton B, Hooper PL, Heathcote JG. Vitritis as the primary manifestation of graft-versus-host disease: a case report with vitreous cytopatholgy. Can J Ophthalmol 2004; 39: 667-71.
62. Cooper B, Shah GK, Sheidow TG, Blinder KJ, Grand MG. Outcome of macular hole surgery in diabetic patients with nonproliferative retinopathy. Retina. 2004 Jun;24(3):360-2.
63. Adatia F, Sheidow TG. Central retinal artery occlusion as the initial ophthalmic presentation of Susac's syndrome Can J Ophthalmol 2004; 39(3): 288-291.
64. Kassam F, Gale JS, Sheidow TG. Intraocular Leukemia as the Primary Manifestation of Relapsing Acute Myeloid Leukemia. Can J Ophthalmol 2003; 38: 613-6.
65. Sheidow TG, Blinder KJ, Holekamp NM, Joseph D, Shah GK, Grand MG, Thomas MA, Sharma S. Outcome Results in Macular Hole Surgery: An Evaluation of Internal Limiting Membrane Peeling with and without ICG. Ophthalmolgy 2003; 110(9):1697-1701.
66. Allibhai ZA, Gale J, Sheidow TG. Central Serous Chorioretinopathy in a patient taking sildenafil citrate. Ophthalmic Surg Lasers Imaging. 2004 35(2):165-7.
67. Sheidow TG, Harbour JW. Photodynamic therapy for circumscribed choroidal hemangioma. CJO 2002; 37(5): 314.
68. Sheidow TG, Gonder JR, and HooperPL. Sub-Tenon's injection for posterior segment surgery Ophthalmology 2001;108 1006
69. Sheidow TG, Hooper PL, Quinn R, Heathcote JG. Expression of vascular endothelial growth factor in ocular melanoma and its relationship to metastases. Br J Ophthalmol 2000; 84(7):750-756
70. Sheidow TG, Nicolle DA, Heathcote JG. Erdheim - Chester Disease: Two Cases of Orbital Involvement. Eye 2000; 14(4):
71. Chaudhary R, Sheidow TG, Gonder JR, Merchea MM. Macular Hole Secondary to YAG Capsulotomy. Br J Opthalmol 1999; 83(6): 755.
72. Sheidow TG, Hooper PL, Bariciak MD. Digital subtraction fluorescein angiography: a new technique for evaluating choroidal neovascular membranes. Can J Ophthalmol 1998; 33(3): 180-187.
73. Sheidow TG, Gonder JR. Cystoid macular edema following combined phacoemulsification and vitrectomy for macular hole.Retina 1998; 18(6): 510-14.
74. Sheidow TG, Gonder JR. Macular hole secondary to retrobulbar needle perforation. Retina 1998; 18(2): 178-180.
