Dr. Lulu Bursztyn
Lulu LCD Bursztyn Msc., MD., FRCS(C)
Neuro-Ophthalmologist and Comprehensive Ophthalmology
Ivey Eye Institute
St. Joseph's Hospital
268 Grosvenor Street
London, ON N6A 4V2
Phone: 519.646.6100 x.66214
Fax: 519.646.6129
Specialty: Neuro-Ophthalmology
Clinical Focus: Neuro-Ophthalmology, Botox Treatment and Cataract Surgery
Residency: Western University
Fellowship (Institution):
Neuro-Ophthalmology, University of Michigan
Appointment: Associate professor
Dr Bursztyn completed an undergrad in chemical engineering at McMaster University followed by a Master's degree in Neuroscience at Queen's University. She completed medical school at Queen's University, ophthalmology residency at Western University and a fellowship in neuro-ophthalmology at the University of Michigan.
Dr. Bursztyn's main areas of academic interest include optic neuropathies, brain tumours and eye movement disorders.
Publications:
1: Tran E, Hadi A, Nair G, Bursztyn LLCD, Fraser JA, Ing EB. Incidence of
Alemtuzumab-Induced Thyroid-Associated Orbitopathy: A Systematic Review and
Meta-Analysis. Ophthalmic Plast Reconstr Surg. 2025 Oct 13. doi:
10.1097/IOP.0000000000003017. Epub ahead of print. PMID: 41082928.
2: Zajner C, Hanna A, Zaman M, Bursztyn LLCD. Extraocular muscle enlargement in
thyroid eye disease: systematic review and meta-analysis. Can J Ophthalmol. 2025
Nov 12:S0008-4182(25)00414-4. doi: 10.1016/j.jcjo.2025.09.014. Epub ahead of
print. PMID: 41052763.
3: Pejhan S, Barra L, Basharat P, Allen LH, Bursztyn LLCD, Proulx A, Chen RY,
Smith M, Hackett M, Hammond R. Clinical Relevance and Prognostic Significance of
Isolated Angiitis of the Vasa Vasorum in Temporal Artery Biopsies. Can J Neurol
Sci. 2025 Sep 12:1-7. doi: 10.1017/cjn.2025.10413. Epub ahead of print. PMID:
40937484.
4: Tran E, Nair G, Bursztyn LLCD, Fraser JA, Ing EB. The Diagnostic Yield of
Antiacetylcholine Receptor Antibodies Versus Antimuscle Kinase Antibodies in
Ocular Myasthenia Gravis: A Meta-Analysis. J Neuroophthalmol. 2025 Aug 1. doi:
10.1097/WNO.0000000000002382. Epub ahead of print. PMID: 40745672.
5: Mannala SA, Bursztyn LLCD. Granuloma annulare following acetazolamide
challenge/rechallenge in a patient with idiopathic intracranial hypertension.
JAAD Case Rep. 2024 Dec 26;57:3-4. doi: 10.1016/j.jdcr.2024.12.015. PMID:
39917447; PMCID: PMC11794954.
6: Zajner C, Patil N, McInnis R, Van Uum S, Fraser A, Ohorodnyk P, Bursztyn
LLCD. Patterns of Extraocular Muscle Enlargement in Graves' Orbitopathy and
Acromegaly. Thyroid. 2025 Jun;35(6):706-710. doi: 10.1089/thy.2024.0438. Epub
2024 Dec 20. Erratum in: Thyroid. 2025 Nov 11. doi: 10.1177/10507256251392924.
PMID: 39705079.
7: Inayat H, McDonald HM, Bursztyn LLCD. Comparison of ChatGPT to ophthalmology
resident and staff consultants on an ophthalmological training tool. Can J
Ophthalmol. 2023 Oct 26:S0008-4182(23)00304-6. doi: 10.1016/j.jcjo.2023.09.011.
Epub ahead of print. PMID: 39492160.
8: Sivakumar GK, Pur DR, Bursztyn LLCD. An Eye on Childbearing, Fertility, and
Lactation Experiences: A Survey of Canadian Ophthalmologists and Trainees. J
Surg Educ. 2024 Dec;81(12):103286. doi: 10.1016/j.jsurg.2024.09.005. Epub 2024
Oct 4. PMID: 39368324.
9: Pur DR, Kryshtalskyj MT, Hutnik CML, Bursztyn LLCD. Association of pre-
residency publications with research productivity in residency, fellowship, and
academic career choice among Canadian ophthalmologists. Can J Ophthalmol. 2024
Dec;59(6):e712-e718. doi: 10.1016/j.jcjo.2024.02.004. Epub 2024 Mar 8. PMID:
38431270.
10: Inayat H, Youn S, Bursztyn LLCD. Utility of online GCA risk models in
predicting the result of temporal artery biopsy within a clinical setting: study
of diagnostic and screening tests. Can J Ophthalmol. 2024 Oct;59(5):e483-e488.
doi: 10.1016/j.jcjo.2023.11.009. Epub 2023 Dec 16. PMID: 38114060.
11: Bell CA, Ko MW, Mackay DD, Bursztyn LLCD, Grossman SN. Spastic Paraplegia
Type 7-Associated Optic Neuropathy: A Case Series. J Neuroophthalmol. 2024 Dec
1;44(4):488-496. doi: 10.1097/WNO.0000000000002039. Epub 2023 Nov 20. PMID:
37983191.
12: Zajner C, McInnis R, Iqbal M, Bursztyn LLCD. Ocular syphilis with coincident
Bartonella infection. Can J Ophthalmol. 2024 Apr;59(2):e179-e181. doi:
10.1016/j.jcjo.2023.10.009. Epub 2023 Oct 22. PMID: 37875247.
13: Pur DR, Sivakumar GK, Bursztyn LLCD, Iordanous Y, de Ribaupierre S.
Strabismus outcomes in pediatric patients undergoing disconnective hemispheric
surgery for intractable epilepsy: a systematic review. Can J Ophthalmol. 2024
Oct;59(5):e547-e556. doi: 10.1016/j.jcjo.2023.07.021. Epub 2023 Aug 25. PMID:
37640228.
14: Pur DR, Iordanous Y, Bursztyn LL. Research productivity of first-year
Canadian ophthalmology residents: a 12-year trend. Can J Ophthalmol. 2024
Aug;59(4):253-258. doi: 10.1016/j.jcjo.2023.06.001. Epub 2023 Jun 20. PMID:
37348839.
15: McInnis RL, Rjoob H, Ohorodnyk P, Fraser JA, Van Uum SHM, Bursztyn LLCD.
Extraocular Muscle Enlargement in Acromegaly. J Neuroophthalmol. 2023 Dec
1;43(4):547-552. doi: 10.1097/WNO.0000000000001866. Epub 2023 May 11. PMID:
37166976.
16: Wu LZ, Orlowski TM, Karunatilake M, Lee S, Mondal P, Kogilwaimath S,
Bursztyn LLCD. Prognostic effect of HIV on visual acuity in ocular syphilis: a
systematic review. Eye (Lond). 2023 Oct;37(15):3271-3281. doi:
10.1038/s41433-023-02504-0. Epub 2023 Mar 21. PMID: 36944709; PMCID:
PMC10564912.
17: McDonald HM, Bursztyn LLCD, Alexander Fraser J. Movie-Like Palinopsia. J
Neuroophthalmol. 2023 Jun 1;43(2):e63-e64. doi: 10.1097/WNO.0000000000001808.
Epub 2023 Jan 18. PMID: 36728090.
18: Youn S, Loshusan B, Armstrong JJ, Fraser JA, Hamann S, Bursztyn LLCD. A
Comparison of Diagnostic Accuracy of Imaging Modalities to Detect Optic Disc
Drusen: The Age of Enhanced Depth Imaging Optical Coherence Tomography. Am J
Ophthalmol. 2023 Apr;248:137-144. doi: 10.1016/j.ajo.2022.12.004. Epub 2022 Dec
11. PMID: 36516916.
19: McDonald HM, Sadikovic B, Sheldon CA, Bursztyn LLCD. Leber Hereditary Optic
Neuropathy in Southwestern Ontario: A Growing List of Mutations. Can J Neurol
Sci. 2023 Sep;50(5):738-744. doi: 10.1017/cjn.2022.279. Epub 2022 Jul 27. PMID:
35892476.
20: Pur DR, Lin T, Iordanous Y, Bursztyn LLCD. Patient perspective on the
participation of ophthalmology residents in their cataract surgery. Can J
Ophthalmol. 2023 Oct;58(5):443-448. doi: 10.1016/j.jcjo.2022.05.002. Epub 2022
May 24. PMID: 35623411.
21: Patil NS, Basilious A, Bursztyn LLCD. Hepatocellular Carcinoma Metastasis
Presenting as Isolated Third Nerve Palsy. Can J Neurol Sci. 2023
May;50(3):466-468. doi: 10.1017/cjn.2022.35. Epub 2022 Mar 31. PMID: 35357303.
22: Nuro E, Bursztyn LL, Mendonça DA, Pelz DM, Budhram A. Neuroimaging Evidence
of Optic Tract Involvement in Metronidazole-Induced Optic Neuropathy. Can J
Neurol Sci. 2023 Mar;50(2):290-291. doi: 10.1017/cjn.2022.21. Epub 2022 Feb 22.
PMID: 35190000.
23: Patil NS, Iqbal MM, Bursztyn LLCD. Conjunctival lymphangiectasia and retinal
angiopathy in hereditary transthyretin amyloidosis. Int J Retina Vitreous. 2022
Jan 6;8(1):4. doi: 10.1186/s40942-021-00357-x. PMID: 34991732; PMCID:
PMC8734248.
24: Lin T, Bursztyn LLCD. Corneal metallic particles after cataract surgery are
safe in magnetic resonance imaging. Can J Ophthalmol. 2022 Jun;57(3):e75. doi:
10.1016/j.jcjo.2021.05.002. Epub 2021 Jun 6. PMID: 34107315.
25: Zhang Y, Kim J, Andrews C, Archer E, Bursztyn L, Grabe H, Margolin E,
Sullivan S, Trobe J. Visual Outcomes in Surgically Treated Intracranial
Meningiomas. J Neuroophthalmol. 2021 Dec 1;41(4):e548-e559. doi:
10.1097/WNO.0000000000001205. PMID: 33870941.
26: McDonald HM, Lin T, Bursztyn LLCD. Multifocal germinoma masquerading as
avoidant restrictive food intake disorder: a case of severely decreased food
intake and malnutrition. Eur J Clin Nutr. 2022 Jan;76(1):173-176. doi:
10.1038/s41430-021-00896-4. Epub 2021 Mar 19. PMID: 33742154.
27: Schulz DC, Orr SMA, Johnstone R, Devlin MK, Sheidow TG, Bursztyn LLCD. The
many faces of ocular syphilis: case-based update on recognition, diagnosis, and
treatment. Can J Ophthalmol. 2021 Oct;56(5):283-293. doi:
10.1016/j.jcjo.2021.01.006. Epub 2021 Feb 4. PMID: 33549544.
28: Petzold A, Biousse V, Bursztyn L, Costello F, Crum A, Digre K, Fraser C,
Fraser JA, Katz B, Jurkute N, Newman N, Lautrup-Battistini J, Lawlor M, Liskova
P, Lorenz B, Malmqvist L, Peragallo J, Sibony P, Subramanian P, Rejdak R,
Nowomiejska K, Touitou V, Warner J, Wegener M, Wong S, Yu-Wai-Man P, Hamann S.
Multirater Validation of Peripapillary Hyperreflective Ovoid Mass-like
Structures (PHOMS). Neuroophthalmology. 2020 Jul 16;44(6):413-414. doi:
10.1080/01658107.2020.1760891. PMID: 33408429; PMCID: PMC7746256.
29: Levy MA, Kerkhof J, Belmonte FR, Kaufman BA, Bhai P, Brady L, Bursztyn LLCD,
Tarnopolsky M, Rupar T, Sadikovic B. Validation and clinical performance of a
combined nuclear-mitochondrial next-generation sequencing and copy number
variant analysis panel in a Canadian population. Am J Med Genet A. 2021
Feb;185(2):486-499. doi: 10.1002/ajmg.a.61998. Epub 2020 Dec 10. PMID: 33300680.
30: Dhoot AS, Just C, Bursztyn LL. Paraneoplastic Ophthalmoplegia as the
Presenting Sign of Paediatric Glioblastoma Multiforme: A Case Report.
Neuroophthalmology. 2020 Sep 22;45(6):397-402. doi:
10.1080/01658107.2020.1817098. PMID: 34720271; PMCID: PMC8555511.
31: Sibony PA, Biousse V, Bursztyn L, Costello F, Digre K, Fraser JA, Fraser CL,
Huna-Baron R, Katz B, Lawlor M, Malmqvist L, Newman NJ, Peragallo J, Petzold A,
Subramanian PS, Warner JEA, Wegener M, Wong S, Hamann S; ODDS Consortium.
Comment on: Morphologic Features of Buried Optic Disc Drusen on En Face Optical
Coherence Tomography and Optical Coherence Tomography Angiography. Am J
Ophthalmol. 2020 Nov;219:369-370. doi: 10.1016/j.ajo.2020.03.055. Epub 2020 Jun
13. PMID: 32546392.
32: Hamann S, Malmqvist L, Wegener M, Fard MA, Biousse V, Bursztyn L, Citirak G,
Costello F, Crum AV, Digre K, Fraser JA, Huna-Baron R, Katz B, Lawlor M, Newman
NJ, Peragallo JH, Petzold A, Sibony PA, Subramanian PS, Warner JEA, Wong SH,
Fraser CL; Optic Disc Drusen Studies Consortium. Young Adults With Anterior
Ischemic Optic Neuropathy: A Multicenter Optic Disc Drusen Study. Am J
Ophthalmol. 2020 Sep;217:174-181. doi: 10.1016/j.ajo.2020.03.052. Epub 2020 Apr
13. PMID: 32298654.
33: Schulz DC, Pandey SK, Bursztyn LLCD. Optic Nerve Atrophy in N-methyl-D-
aspartate (NMDA) Encephalitis. Can J Neurol Sci. 2020 Jan;47(1):139-141. doi:
10.1017/cjn.2019.325. Epub 2019 Dec 4. PMID: 31724524.
34: Quinn MP, Bursztyn LL, Sharma M. Putaminal Diffusion Restriction in a Case
of Methanol Toxicity with Clinical Recovery. Can J Neurol Sci. 2020
Jan;47(1):115-116. doi: 10.1017/cjn.2019.303. Epub 2019 Nov 18. PMID: 31566156.
35: Bursztyn LLCD, De Lott LB, Petrou M, Cornblath WT. Sensitivity of orbital
magnetic resonance imaging in acute demyelinating optic neuritis. Can J
Ophthalmol. 2019 Apr;54(2):242-246. doi: 10.1016/j.jcjo.2018.05.013. Epub 2018
Aug 24. PMID: 30975349; PMCID: PMC6698913.
36: Ing EB, Miller NR, Nguyen A, Su W, Bursztyn LLCD, Poole M, Kansal V, Toren
A, Albreki D, Mouhanna JG, Muladzanov A, Bernier M, Gans M, Lee D, Wendel C,
Sheldon C, Shields M, Bellan L, Lee-Wing M, Mohadjer Y, Nijhawan N, Tyndel F,
Sundaram ANE, Ten Hove MW, Chen JJ, Rodriguez AR, Hu A, Khalidi N, Ing R, Wong
SWK, Torun N. Neural network and logistic regression diagnostic prediction
models for giant cell arteritis: development and validation. Clin Ophthalmol.
2019 Feb 21;13:421-430. doi: 10.2147/OPTH.S193460. PMID: 30863010; PMCID:
PMC6388759.
37: Malmqvist L, Bursztyn L, Costello F, Digre K, Fraser JA, Fraser C, Katz B,
Lawlor M, Petzold A, Sibony P, Warner J, Wegener M, Wong S, Hamann S.
Peripapillary Hyperreflective Ovoid Mass-Like Structures: Is It Optic Disc
Drusen or Not?: Response. J Neuroophthalmol. 2018 Dec;38(4):568-570. doi:
10.1097/WNO.0000000000000674. PMID: 29901493.
38: Malmqvist L, Bursztyn L, Costello F, Digre K, Fraser JA, Fraser C, Katz B,
Lawlor M, Petzold A, Sibony P, Warner J, Wegener M, Wong S, Hamann S. The Optic
Disc Drusen Studies Consortium Recommendations for Diagnosis of Optic Disc
Drusen Using Optical Coherence Tomography. J Neuroophthalmol. 2018
Sep;38(3):299-307. doi: 10.1097/WNO.0000000000000585. PMID: 29095768.
39: Bursztyn L, Woodward MA, Cornblath WT, Grabe HM, Trobe JD, Niziol L, De Lott
LB. Accuracy and Reliability of a Handheld, Nonmydriatic Fundus Camera for the
Remote Detection of Optic Disc Edema. Telemed J E Health. 2018
May;24(5):344-350. doi: 10.1089/tmj.2017.0120. Epub 2017 Oct 13. PMID: 29027884;
PMCID: PMC5953213.
40: Nari J, Allen LH, Bursztyn LLCD. Accuracy of referral diagnosis to an
emergency eye clinic. Can J Ophthalmol. 2017 Jun;52(3):283-286. doi:
10.1016/j.jcjo.2016.12.011. Epub 2017 Feb 20. PMID: 28576210.
41: Ross M, Bursztyn L, Superstein R, Gans M. Multiple Cranial Nerve Palsies in
Giant Cell Arteritis. J Neuroophthalmol. 2017 Dec;37(4):398-400. doi:
10.1097/WNO.0000000000000529. PMID: 28538036.
42: Le K, Bursztyn L, Rootman D, Harissi-Dagher M. National survey of Canadian
ophthalmology residency education. Can J Ophthalmol. 2016 Jun;51(3):219-25. doi:
10.1016/j.jcjo.2016.04.017. PMID: 27316273.
43: Sharma RA, Bursztyn LL, Golesic E, Mather R, Tingey DP. Comparison of
intraocular pressure post penetrating keratoplasty vs Descemet's stripping
endothelial keratoplasty. Can J Ophthalmol. 2016 Feb;51(1):19-24. doi:
10.1016/j.jcjo.2015.09.014. PMID: 26874154.
44: Breker DA, Stacey AW, Srinivasan A, Bursztyn LL, Trobe JD, Johnson MW.
Vision Loss Caused by Retinal and Lateral Geniculate Nucleus Infarction in H1N1
Influenza. J Neuroophthalmol. 2015 Sep;35(3):265-9. doi:
10.1097/WNO.0000000000000247. PMID: 25887303.
45: Kauh CY, Bursztyn LL. Positive Apraclonidine Test in Horner Syndrome Caused
by Thalamic Hemorrhage. J Neuroophthalmol. 2015 Sep;35(3):287-8. doi:
10.1097/WNO.0000000000000222. PMID: 25768246.
46: Bursztyn LL, Belrose JC, Coupland SG, Fraser JA, Proulx AA. Remission of
nonparaneoplastic autoimmune retinopathy after minimal steroid treatment. Retin
Cases Brief Rep. 2015 Spring;9(2):173-6. doi: 10.1097/ICB.0000000000000131.
PMID: 25764315.
47: Bursztyn LL, Masri M, Sheidow TG. Severe visual loss secondary to retinal
toxicity after intravenous use of bisphosphonate in an eye with known
chloroquine maculopathy. Retin Cases Brief Rep. 2014 Fall;8(4):322-5. doi:
10.1097/ICB.0000000000000055. PMID: 25372538.
48: Bursztyn LL, Sharan S, Walsh L, LaRoche GR, Robitaille J, De Becker I. Has
rising pediatric obesity increased the incidence of idiopathic intracranial
hypertension in children? Can J Ophthalmol. 2014 Feb;49(1):87-91. doi:
10.1016/j.jcjo.2013.09.015. PMID: 24513363.
49: Bursztyn LL, Makar I. Congenital trochlear-oculomotor synkinesis. J
Neuroophthalmol. 2014 Mar;34(1):64-6. doi: 10.1097/WNO.0000000000000091. PMID:
24413161.
50: Bursztyn LL, Hyrcza MD, Allen LH, Berean KW, Wehrli B. Low-grade intraductal
carcinoma of the lacrimal gland. Orbit. 2014 Apr;33(2):135-8. doi:
10.3109/01676830.2013.851257. Epub 2013 Nov 6. PMID: 24195727.
51: Lownie SP, Pinkoski C, Bursztyn LL, Nicolle DA. Eyelid and eye movements
following fourth to third nerve anastomosis. J Neuroophthalmol. 2013
Mar;33(1):66-8. doi: 10.1097/WNO.0b013e318270316b. PMID: 23235433.
52: Bursztyn LL, Flanagan JR. Sensorimotor memory of weight asymmetry in object
manipulation. Exp Brain Res. 2008 Jan;184(1):127-33. doi:
10.1007/s00221-007-1173-z. Epub 2007 Oct 24. PMID: 17957361.
53: Bursztyn LL, Ganesh G, Imamizu H, Kawato M, Flanagan JR. Neural correlates
of internal-model loading. Curr Biol. 2006 Dec 19;16(24):2440-5. doi:
10.1016/j.cub.2006.10.051. PMID: 17174919.
