Promoting the health of women is our life’s work here in the Department of Obstetrics and Gynaecology, Schulich School of Medicine & Dentistry at Western University. We are happy to be able to share with you the scope of our activities and provide you with more information on what we do.
Our research aims to understand how babies that do not grow normally, because of too little nutrition or too much nutrition while still inside the womb, change their metabolism, the way the body uses energy, to live and grow. These babies change their metabolism, or are reprogrammed, under the unfavorable in utero environment to survive inside the womb. However these programming changes are now postulated to lead to an increased risk of childhood and adult non-communicable diseases such as insulin resistance, obesity, hypertension and the origins of heart disease, collectively termed the metabolic syndrome. Our work aims to understand and develop ways to modulate the changes in these children's metabolism inside and outside the womb. Read more
Zhang B, Denomme MM, White CR, Leung K, Lee MB, Greene ND, Mann MR, Trasler JM, Baltz JM. FASEB J. 2014 Dec 2. pii: fj.14-261131. PMID: 25466894
Vilos G, Vilos A. BJOG. 2015 Jan;122(1):142. doi: 10.1111/1471-0528.13166. No abstract available. PMID: 25545905