Schulich school of Medicine and Dentistry logo Department of Biochemistry Schulich School of Medicine & Dentistry

Recent Publications

picture of Dr. Shawn Li

Jan 2017   Feb 2017   Mar 2017   Apr 2017   May 2017   June 2017   July 2017

Aug 2017   Sept 2017


Sept 2017

  1. Ellis KL, Boffa MB, Sahebkar A, Koschinsky ML, Watts GF. The renaissance of lipoprotein(a): Brave new world for preventive cardiology? Prog Lipid Res. 2017 Sep 6. pii: S0163-7827(17)30041-3.
  2. Ao M, Chavez MB, Chu EY, Hemstreet KC, Yin Y, Yadav MC, Millán JL, Fisher LW, Goldberg HA, Somerman MJ, Foster BL. Overlapping functions of bone sialoprotein and pyrophosphate regulators in directing cementogenesis. Bone. 2017 Sep 1;105:134-147.
  3. Iacocca MA, Wang J, Dron JS, Robinson JF, McIntyre AD, Cao H, Hegele RA. Use of next-generation sequencing to detect LDLR gene copy number variation in familial hypercholesterolemia. J Lipid Res. 2017 Sep 5. pii: jlr.D079301.
  4. Dron JS, Wang J, Low-Kam C, Khetarpal SA, Robinson JF, McIntyre AD, Ban MR, Cao H, Rhainds D, Dubé MP, Rader DJ, Lettre G, Tardif JC, Hegele RA. Polygenic determinants in extremes of high-density lipoprotein cholesterol. J Lipid Res. 2017 Sep 4. pii: jlr.M079822.
  5. Sundaram M, Curtis KR, Amir Alipour M, LeBlond ND, Margison KD, Yaworski RA, Parks RJ, McIntyre AD, Hegele RA, Fullerton MD, Yao Z. The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation. J Lipid Res. 2017 Sep 8. pii: jlr.M077313.
  6. Jayawardena DP, Heinemann IU, Stillman MJ. Zinc binds non-cooperatively to human liver metallothionein 2a at physiological pH. Biochem Biophys Res Commun. 2017 Sep 1. pii: S0006-291X(17)31722-9.
  7. Desai R, Kim K, Chen HCBAW, Bi Y, Mann MR, Turk MA, Chung CZ, Heinemann IU. Minimal requirements for reverse polymerization and tRNA repair by tRNA(His) guanylyltransferase. RNA Biol. 2017 Sep 13:0.
  8. Suzuki A, Yanagi M, Takeda T, Hudson RHE, Saito Y. The fluorescently responsive 3-(naphthalen-1-ylethynyl)-3-deaza-2'-deoxyguanosine discriminates cytidine via the DNA minor groove. Org Biomol Chem. 2017 Sep 7.
  9. Shirley B, Li Y, Knoll JHM, Rogan PK. Expedited Radiation Biodosimetry by Automated Dicentric Chromosome Identification (ADCI) and Dose Estimation. J Vis Exp. 2017 Sep 4;(127).
  10. Hannouf MB, Winquist E, Mahmud SM, Brackstone M, Sarma S, Rodrigues G, Rogan PK, Hoch JS, Zaric GS. The Potential Clinical and Economic Value of Primary Tumour Identification in Metastatic Cancer of Unknown Primary Tumour: A Population-Based Retrospective Matched Cohort Study. PharmacoEconomics Open. 2017.
  11. Khalili Yazdi A, Namjoshi S, Hackett J, Ghonaim N, Shilton BH. Characterization of a Polypeptide Binding Site in the DEAD Motor of the SecA ATPase. FEBS Lett. 2017 Sep 1.
  12. Zuanazzi D, Arts EJ, Jorge PK, Mulyar Y, Gibson R, Xiao Y, Bringel Dos Santos M, Machado MAAM, Siqueira WL. Postnatal Identification of Zika Virus Peptides from Saliva. J Dent Res. 2017 Sep;96(10):1078-1084.

Aug 2017

  1. Kerkhof J, Schenkel LC, Reilly J, McRobbie S, Aref-Eshghi E, Stuart A, Rupar CA, Adams P, Hegele RA, Lin H, Rodenhiser D, Knoll J, Ainsworth PJ, Sadikovic B. Clinical Validation of Copy Number Variant Detection from Targeted Next-Generation Sequencing Panels. J Mol Diagn. 2017 Aug 14. pii: S1525-1578(17)30207-6.
  2. Aref-Eshghi E, Schenkel LC, Lin H, Skinner C, Ainsworth P, Paré G, Siu V, Rodenhiser D, Schwartz C, Sadikovic B. Clinical Validation of a Genome-Wide DNA Methylation Assay for Molecular Diagnosis of Imprinting Disorders. J Mol Diagn. 2017 Aug 11. pii: S1525-1578(17)30263-5.
  3. Tong JG, Valdes YR, Sivapragasam M, Barrett JW, Bell JC, Stojdl D, DiMattia GE, Shepherd TG. Spatial and temporal epithelial ovarian cancer cell heterogeneity impacts Maraba virus oncolytic potential. BMC Cancer. 2017 Aug 30;17(1):594.
  4. Rosenson RS, Brewer HB Jr, Barter PJ, Björkegren JLM, Chapman MJ, Gaudet D, Kim DS, Niesor E, Rye KA, Sacks FM, Tardif JC, Hegele RA. HDL and atherosclerotic cardiovascular disease: genetic insights into complex biology. Nat Rev Cardiol. 2017 Aug 10.
  5. Konermann L. Molecular Dynamics Simulations on Gas Phase Proteins with Mobile Protons: Inclusion of All-Atom Charge Solvation. J Phys Chem B. 2017 Aug 4.
  6. Mathieu P, Arsenault BJ, Boulanger MC, Bossé Y, Koschinsky ML. Pathobiology of Lp(a) in calcific aortic valve disease. Expert Rev Cardiovasc Ther. 2017 Aug 17.
  7. Kuljanin M, Brown CFC, Raleigh MJ, Lajoie GA, Flynn LE. Collagenase treatment enhances proteomic coverage of low-abundance proteins in decellularized matrix bioscaffolds. Biomaterials. 2017 Aug 13;144:130-143.
  8. Crosara KTB, Moffa EB, Xiao Y, Siqueira WL. Merging in-silico and in vitro salivary protein complex partners using the STRING database: A tutorial. J Proteomics. 2017 Aug 3. pii: S1874-3919(17)30266-X.
  9. Goh E, Guerin A, Lazier J, Goobie S, Nelson TN, Agatep R, Siu VM, Niederhoffer KY, Richer J. Choosing Wisely Canada: The Canadian College of Medical Geneticists' (CCMG) list of five items physicians and patients should question. J Med Genet. 2017 Aug 19. pii: jmedgenet-2017-104924.

July 2017

  1. Romagnuolo R, Scipione CA, Marcovina SM, Gemin M, Seidah NG, Boffa MB, Koschinsky ML. Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9. PLoS One. 2017 Jul 27;12(7):e0180869.
  2. Ishak CA, Coschi CH, Roes MV, Dick FA. Disruption of CDK-resistant chromatin association by pRB causes DNA damage, mitotic errors, and reduces Condensin II recruitment. Cell Cycle. 2017 Jul 19:0.
  3. Herzmann C, Zubiaurre-Elorza L, Wild CJ, Linke AC, Han VK, Lee DSC, Cusack R. Using Functional Magnetic Resonance Imaging to Detect Preserved Function in a Preterm Infant with Brain Injury. J Pediatr. 2017 Jul 20. pii: S0022-3476(17)30913-7.
  4. Blom DJ, Averna MR, Meagher EA, du Toit Theron H, Sirtori CR, Hegele RA, Shah PK, Gaudet D, Stefanutti C, Vigna GB, Larrey D, Bloedon LT, Foulds P, Rader DJ, Cuchel M. Long-Term Efficacy and Safety of the Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide in Patients With Homozygous Familial Hypercholesterolemia. Circulation. 2017 Jul 18;136(3):332-335.
  5. Dron JS, Hegele RA. Genetics of Triglycerides and the Risk of Atherosclerosis. Curr Atheroscler Rep. 2017 Jul;19(7):31.
  6. Stahel P, Xiao C, Hegele RA, Lewis GF. Polygenic Risk for Hypertriglyceridemia Can Mimic a Major Monogenic Mutation. Ann Intern Med. 2017 Jul 25.
  7. Diner RE, Noddings CM, Lian NC, Kang AK, McQuaid JB, Jablanovic J, Espinoza JL, Nguyen NA, Anzelmatti MA Jr, Jansson J, Bielinski VA, Karas BJ, Dupont CL, Allen AE, Weyman PD. Diatom centromeres suggest a mechanism for nuclear DNA acquisition. Proc Natl Acad Sci U S A. 2017 Jul 3. pii: 201700764.
  8. Konermann L. Addressing a Common Misconception: Ammonium Acetate as Neutral pH "Buffer" for Native Electrospray Mass Spectrometry. J Am Soc Mass Spectrom. 2017 Jul 14.
  9. Xiao Y, Shaw GS, Konermann L. Calcium-Mediated Control of S100 Proteins: Allosteric Communication via an Agitator/Signal Blocking Mechanism. J Am Chem Soc. 2017 Jul 31.
  10. Kuljanin M, Bell GI, Sherman SE, Lajoie GA, Hess DA. Proteomic characterisation reveals active Wnt-signalling by human multipotent stromal cells as a key regulator of beta cell survival and proliferation. Diabetologia. 2017 Jul 14.
  11. George S, Wang SM, Bi Y, Treidlinger M, Barber KR, Shaw GS, O'Donoghue P. Ubiquitin phosphorylated at Ser57 hyper-activates parkin. Biochim Biophys Acta. 2017 Jul 6. pii: S0304-4165(17)30213-1.
  12. Salemi LM, Maitland MER, Yefet ER, Schild-Poulter C. Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex. BMC Cancer. 2017 Jul;17:460.

June 2017

  1. Scipione CA, McAiney JT, Simard DJ, Bazzi ZA, Gemin M, Romagnuolo R, Macrae FL, Ariëns RA, Hegele RA, Auld J, Gauld JW, Boffa MB, Koschinsky ML. Characterization of the I4399M variant of apolipoprotein(a): Implications for altered prothrombotic properties of lipoprotein(a). J Thromb Haemost. 2017 Jun 20.
  2. Berg MD, Hoffman KS, Genereaux J, Mian S, Trussler RS, Haniford DB, O'Donoghue P, Brandl CJ. Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae. Genetics. 2017 Jun 2. pii: genetics.117.203232.
  3. Wild CJ, Linke AC, Zubiaurre-Elorza L, Herzmann C, Duffy H, Han VK, Lee DSC, Cusack R. Adult-like processing of naturalistic sounds in auditory cortex by 3-and 9-month old infants. Neuroimage. 2017 Jun 22. pii: S1053-8119(17)30506-2.
  4. Berberich AJ, Hegele RA. Lomitapide for the treatment of hypercholesterolemia. Expert Opin Pharmacother. 2017 Jun 9.
  5. Montero-Odasso M, Pieruccini-Faria F, Bartha R, Black SE, Finger E, Freedman M, Greenberg B, Grimes DA, Hegele RA, Hudson C, Kleinstiver PW, Lang AE, Masellis M, McLaughlin PM, Munoz DP, Strother S, Swartz RH, Symons S, Tartaglia MC, Zinman L, Strong MJ; ONDRI Investigators, McIlroy W. Motor Phenotype in Neurodegenerative Disorders: Gait and Balance Platform Study Design Protocol for the Ontario Neurodegenerative Research Initiative (ONDRI). J Alzheimers Dis. 2017 Jun 27.
  6. Karamichalis R, Kari L. MoDMaps3D: An interactive webtool for the quantification and 3D visualization of interrelationships in a dataset of DNA sequences. Bioinformatics. 2017 Jun 10.
  7. McClatchie T, Meredith M, Ouédraogo MO, Slow S, Lever M, Mann MRW, Zeisel SH, Trasler JM, Baltz JM. Betaine is accumulated via transient choline dehydrogenase activation during Mouse oocyte meiotic maturation. J Biol Chem. 2017 Jun 29. pii: jbc.M117.803080.
  8. Athwal GS, Faber KJ, O'Gorman DB. Response to: Can 16S rRNA PCR be the solution for a rapid detection of Propionibacterium acnes in surgical shoulder or spine samples? Comments on "A rapid method for detecting Propionibacterium acnes in surgical biopsy specimens from the shoulder". J Shoulder Elbow Surg. 2017 Jun;26(6):e205.
  9. Yang XR, Devi BCR, Sung H, Guida J, Mucaki EJ, Xiao Y, Best A, Garland L, Xie Y, Hu N, Rodriguez-Herrera M, Wang C, Jones K, Luo W, Hicks B, Tang TS, Moitra K, Rogan PK, Dean M. Prevalence and spectrum of germline rare variants in BRCA1/2 and PALB2 among breast cancer cases in Sarawak, Malaysia. Breast Cancer Res Treat. 2017 Jun 29.
  10. Abbott JA, Guth E, Kim C, Regan C, Siu VM, Rupar CA, Demeler B, Francklyn CS, Robey-Bond SM. The Usher Syndrome Type IIIB Histidyl-tRNA Synthetase Mutation Confers Temperature Sensitivity. Biochemistry. 2017 Jun 20.
  11. Salemi LM, Maitland MER, McTavish CJ, Schild-Poulter C. Cell signalling pathway regulation by RanBPM: molecular insights and disease implications. Open Biol. 2017 Jun;7(6). pii: 170081.
  12. Dunkerley KM, Shaw GS. RBR Ubiquitin Transfer: Not Simply an "Open" and "Closed" Case? Structure. 2017 Jun 6;25(6):817-819.
  13. Renaud JB, Kelman MJ, McMullin DR, Yeung KK, Sumarah MW. Application of C8 liquid chromatography-tandem mass spectrometry for the analysis of enniatins and bassianolides. J Chromatogr A. 2017 Jun 3. pii: S0021-9673(17)30832-4.

May 2017

  1. Lackie RE, Maciejewski A, Ostapchenko VG, Marques-Lopes J, Choy WY, Duennwald ML, Prado VF, Prado MAM. The Hsp70/Hsp90 Chaperone Machinery in Neurodegenerative Diseases. Front Neurosci. 2017 May 16;11:254.
  2. Leung AA, Daskalopoulou SS, Dasgupta K, McBrien K, Butalia S, Zarnke KB, Nerenberg K, Harris KC, Nakhla M, Cloutier L, Gelfer M, Lamarre-Cliche M, Milot A, Bolli P, Tremblay G, McLean D, Tobe SW, Ruzicka M, Burns KD, Vallée M, Prasad GVR, Gryn SE, Feldman RD, Selby P, Pipe A, Schiffrin EL, McFarlane PA, Oh P, Hegele RA, Khara M, Wilson TW, Penner SB, Burgess E, Sivapalan P, Herman RJ, Bacon SL, Rabkin SW, Gilbert RE, Campbell TS, Grover S, Honos G, Lindsay P, Hill MD, Coutts SB, Gubitz G, Campbell NRC, Moe GW, Howlett JG, Boulanger JM, Prebtani A, Kline G, Leiter LA, Jones C, Côté AM, Woo V, Kaczorowski J, Trudeau L, Tsuyuki RT, Hiremath S, Drouin D, Lavoie KL, Hamet P, Grégoire JC, Lewanczuk R, Dresser GK, Sharma M, Reid D, Lear SA, Moullec G, Gupta M, Magee LA, Logan AG, Dionne J, Fournier A, Benoit G, Feber J, Poirier L, Padwal RS, Rabi DM; Hypertension Canada. Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults. Can J Cardiol. 2017 May;33(5):557-576.
  3. Hegele RA. Insulin affordability. Lancet Diabetes Endocrinol. 2017 May;5(5):324.
  4. Hegele RA. PCSK9 inhibitors: smooth sailing or a little turbulence ahead? Lancet Diabetes Endocrinol. 2017 May 5. pii: S2213-8587(17)30150-X.
  5. Iacocca MA, Hegele RA. Recent advances in genetic testing for familial hypercholesterolemia. Expert Rev Mol Diagn. 2017 May 19.
  6. Liu Y, Conlon DM, Bi X, Slovik KJ, Shi J, Edelstein HI, Millar JS, Javaheri A, Cuchel M, Pashos EE, Iqbal J, Hussain MM, Hegele RA, Yang W, Duncan SA, Rader DJ, Morrisey EE. Lack of MTTP Activity in Pluripotent Stem Cell-Derived Hepatocytes and Cardiomyocytes Abolishes apoB Secretion and Increases Cell Stress. Cell Rep. 2017 May 16;19(7):1456-1466.
  7. Hooper AJ, McCormick SPA, Hegele RA, Burnett JR. Clinical utility gene card for: Tangier disease. Eur J Hum Genet. 2017 May 24. 
  8. Chung CZ, Seidl LE, Mann MR, Heinemann IU. Tipping the balance of RNA stability by 3' editing of the transcriptome. Biochim Biophys Acta. 2017 May 5. pii: S0304-4165(17)30147-2.
  9. Nsaibia MJ, Boulanger MC, Bouchareb R, Mkannez G, Le Quang K, Hadji F, Argaud D, Dahou A, Bossé Y, Koschinsky ML, Pibarot P, Arsenault BJ, Marette A, Mathieu P. OxLDL-derived lysophosphatidic acid promotes the progression of aortic valve stenosis through a LPAR1-RhoA-NF-κB pathway. Cardiovasc Res. 2017 May 4.
  10. Sun W, Liu Y, Lajoie G, Ma B, Zhang K. An Improved Approach for N-linked Glycan Structure Identification from HCD MS/MS Spectra. IEEE/ACM Trans Comput Biol Bioinform. 2017 May 5.
  11. Thandapani P, Couturier AM, Yu Z, Li X, Couture JF, Li S, Masson JY, Richard S. Lysine methylation of FEN1 by SET7 is essential for its cellular response to replicative stress. Oncotarget. 2017 May 22.
  12. Okumu DO, East MP, Levine M, Herring LE, Zhang R, Gilbert TSK, Litchfield DW, Zhang Y, Graves LM. BIRC6 mediates imatinib resistance independently of Mcl-1. PLoS One. 2017 May 16;12(5):e0177871.
  13. Huang J, Khan A, Au BC, Barber DL, López-Vásquez L, Prokopishyn NL, Boutin M, Rothe M, Rip JW, Abaoui M, Nagree MS, Dworski S, Schambach A, Keating A, West ML, Klassen J, Turner PV, Sirrs S, Rupar CA, Auray-Blais C, Foley R, Medin JA. Lentivector Iterations and Pre-Clinical Scale-Up/Toxicity Testing: Targeting Mobilized CD34(+) Cells for Correction of Fabry Disease. Mol Ther Methods Clin Dev. 2017 May 12;5:241-258.
  14. Mucaki EJ, Baranova K, Pham HQ, Rezaeian I, Angelov D, Ngom A, Rueda L, Rogan PK. Predicting Outcomes of Hormone and Chemotherapy in the Molecular Taxonomy of Breast Cancer International Consortium (METABRIC) Study by Biochemically-inspired Machine Learning [version 3; referees: 2 approved]. F1000Research 2017, 5:2124.
  15. Basiri T, Johnson ND, Moffa EB, Mulyar Y, Serra Nunes PL, Machado MAAM, Siqueira WL. Duplicated or Hybridized Peptide Functional Domains Promote Oral Homeostasis. J Dent Res. 2017 May 1:22034517708552.
  16. Hassan HM, Kolendowski B, Isovic M, Bose K, Dranse HJ, Sampaio AV, Underhill TM, Torchia J. Regulation of Active DNA Demethylation through RAR-Mediated Recruitment of a TET/TDG Complex. Cell Rep. 2017 May 23;19(8):1685-1697. 

Apr 2017

  1. Maciejewski A, Prado VF, Prado MA, Choy WY. Molecular basis for the interaction between stress-inducible phosphoprotein 1 (STIP1) and S100A1. Biochem J. 2017 Apr 13. pii: BCJ20161055.
  2. Abu Shehab M, Biggar K, Singal SS, Nygard K, Shun-Cheng Li S, Jansson T, Gupta MB. Exposure of decidualized HIESC to low oxygen tension and leucine deprivation results in increased IGFBP-1 phosphorylation and reduced IGF-I bioactivity. Mol Cell Endocrinol. 2017 Apr 20. pii: S0303-7207(17)30218-6.
  3. Lo M, Zubiaurre-Elorza L, Wild C, Linke AC, Lee DSC, Han VK, Cusack R. Brainstem shape is affected by clinical course in the neonatal intensive care unit. Neuroimage Clin. 2017 Apr 12;15:62-70.
  4. Hegele RA. Editorial introduction. Curr Opin Lipidol. 2017 Apr;28(2):v.
  5. Xiao C, Hegele RA, Lewis GF. Treatment of Severe Hypercholesterolemia in a Woman With Advanced Primary Sclerosing Cholangitis. JAMA Cardiol. 2017 Apr 5.
  6. Ference BA, Ginsberg HN, Graham I, Ray KK, Packard CJ, Bruckert E, Hegele RA, Krauss RM, Raal FJ, Schunkert H, Watts GF, Borén J, Fazio S, Horton JD, Masana L, Nicholls SJ, Nordestgaard BG, van de Sluis B, Taskinen MR, Tokgözoglu L, Landmesser U, Laufs U, Wiklund O, Stock JK, Chapman MJ, Catapano AL. Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel. Eur Heart J. 2017 Apr 24.
  7. Liu Y, Ma B, Zhang K, Lajoie G. An Approach for Peptide Identification by De Novo Sequencing of Mixture Spectra. IEEE/ACM Trans Comput Biol Bioinform. 2017 Mar-Apr;14(2):326-336.
  8. Elkerton JS, Xu Y, Pickering JG, Ward AD. Differentiation of arterioles from venules in mouse histology images using machine learning. J Med Imaging (Bellingham). 2017 Apr;4(2):021104.
  9. Kumar A, Chaugule VK, Condos TEC, Barber KR, Johnson C, Toth R, Sundaramoorthy R, Knebel A, Shaw GS, Walden H. Parkin-phosphoubiquitin complex reveals cryptic ubiquitin-binding site required for RBR ligase activity. Nat Struct Mol Biol. 2017 Apr 17.
  10. Klank RL, Decker Grunke SA, Bangasser BL, Forster CL, Price MA, Odde TJ, SantaCruz KS, Rosenfeld SS, Canoll P, Turley EA, McCarthy JB, Ohlfest JR, Odde DJ. Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level. Cell Rep. 2017 Apr 18;19(3):668. 

Mar 2017

  1. Schenkel LC, Rodenhiser D, Siu V, McCready E, Ainsworth P, Sadikovic B. Constitutional Epi/Genetic Conditions: Genetic, Epigenetic, and Environmental Factors. J Pediatr Genet. 2017 Mar;6(1):30-41.
  2. Schenkel LC, Kernohan KD, McBride A, Reina D, Hodge A, Ainsworth PJ, Rodenhiser DI, Pare G, Bérubé NG, Skinner C, Boycott KM, Schwartz C, Sadikovic B. Identification of epigenetic signature associated with alpha thalassemia/mental retardation X-linked syndrome. Epigenetics Chromatin. 2017 Mar 10;10:10.
  3. Thwaites MJ, Cecchini MJ, Talluri S, Passos DT, Carnevale J, Dick FA. Multiple molecular interactions redundantly contribute to RB-mediated cell cycle control. Cell Div. 2017 Mar 14;12:3.
  4. Celis JS, Edgell DR, Stelbrink B, Wibberg D, Hauffe T, Blom J, Kalinowski J, Wilke T. Evolutionary and biogeographical implications of degraded LAGLIDADG endonuclease functionality and group I intron occurrence in stony corals (Scleractinia) and mushroom corals (Corallimorpharia). PLoS One. 2017 Mar 9;12(3):e0173734.
  5. Youssef A, Aboalola D, Han VK. The Roles of Insulin-Like Growth Factors in Mesenchymal Stem Cell Niche. Stem Cells Int. 2017;2017:9453108.
  6. Filler G, Lee M, Hegele RA. Barriers to the Implementation of Lipoprotein Apheresis in Canada. Can J Cardiol. 2017 Mar;33(3):409-411.
  7. Dron JS, Hegele RA. Genetics of Lipid and Lipoprotein Disorders and Traits. Curr Genet Med Rep. 2016;4(3):130-141.
  8. Mandacaru SC, do Vale LH, Vahidi S, Xiao Y, Skinner OS, Ricart CA, Kelleher NL, de Sousa MV, Konermann L. Characterizing the Structure and Oligomerization of Major Royal Jelly Protein 1 (MRJP1) by Mass Spectrometry and Complementary Biophysical Tools. Biochemistry. 2017 Mar 7.
  9. Sherman SE, Kuljanin M, Cooper TT, Putman DM, Lajoie GA, Hess DA. High Aldehyde Dehydrogenase Activity Identifies a Subset of Human Mesenchymal Stromal Cells with Vascular Regenerative Potential. Stem Cells. 2017 Mar 15.
  10. Nuñez de Villavicencio-Diaz T, Rabalski AJ, Litchfield DW. Protein Kinase CK2: Intricate Relationships within Regulatory Cellular Networks. Pharmaceuticals (Basel). 2017 Mar 5;10(1). pii: E27.
  11. Watson A, Nong Z, Yin H, O'Neil C, Fox S, Balint B, Guo R, Leo O, Chu MW, Gros R, Pickering JG. Nicotinamide Phosphoribosyltransferase in Smooth Muscle Cells Maintains Genome Integrity, Resists Aortic Medial Degeneration and Is Suppressed in Human Thoracic Aortic Aneurysm Disease. Circ Res. 2017 Mar 29. pii: CIRCRESAHA.116.310022.
  12. Hannouf MB, Winquist E, Mahmud SM, Brackstone M, Sarma S, Rodrigues G, Rogan PK, Hoch JS, Zaric GS. The Clinical Significance of Occult Gastrointestinal Primary Tumours in Metastatic Cancer: A Population Retrospective Cohort Study. Cancer Res Treat. 2017 Mar 21.
  13. Abdallah MN, Tran SD, Abughanam G, Laurenti M, Zuanazzi D, Mezour MA, Xiao Y, Cerruti M, Siqueira WL, Tamimi F. Biomaterial surface proteomic signature determines interaction with epithelial cells. Acta Biomater. 2017 Mar 1. pii: S1742-7061(17)30159-9.
  14. Terças AL, Marques SG, Moffa EB, Alves MB, de Azevedo CM, Siqueira WL, Monteiro CA. Antifungal Drug Susceptibility of Candida Species Isolated from HIV-Positive Patients Recruited at a Public Hospital in São Luís, Maranhão, Brazil. Front Microbiol. 2017 Mar 2;8:298.
  15. Caughlin S, Park DH, Yeung KK, Cechetto DF, Whitehead SN. Sublimation of DAN Matrix for the Detection and Visualization of Gangliosides in Rat Brain Tissue for MALDI Imaging Mass Spectrometry. J Vis Exp. 2017 Mar 23;(121).

Feb 2017

  1. Ellis MJ, Trussler RS, Charles O, Haniford DB. A transposon-derived small RNA regulates gene expression in Salmonella Typhimurium. Nucleic Acids Res. 2017 Feb 21.
  2. Dron JS, Hegele RA. Complexity of mechanisms among human proprotein convertase subtilisin-kexin type 9 variants. Curr Opin Lipidol. 2017 Feb 2.
  3. Ueda M, Dunbar RL, Wolska A, Sikora TU, Escobar MD, Seliktar N, deGoma E, DerOhannessian S, Morrell L, McIntyre AD, Burke F, Sviridov D, Amar M, Shamburek RD, Freeman L, Hegele RA, Remaley AT, Rader DJ. A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency with Severe Triglyceridemia and Pancreatitis. J Clin Endocrinol Metab. 2017 Feb 13.
  4. Aljenedil S, Hegele RA, Genest J, Awan Z. Estrogen-associated severe hypertriglyceridemia with pancreatitis. J Clin Lipidol. 2017 Jan - Feb;11(1):297-300.
  5. Rosenson RS, Najera SD, Hegele RA. Heterozygous familial hypercholesterolemia presenting as chylomicronemia syndrome. J Clin Lipidol. 2017 Jan - Feb;11(1):294-296.
  6. Samsoondar JP, Burke AC, Sutherland BG, Telford DE, Sawyez CG, Edwards JY, Pinkosky SL, Newton RS, Huff MW. Prevention of Diet-Induced Metabolic Dysregulation, Inflammation, and Atherosclerosis in Ldlr-/- Mice by Treatment With the ATP-Citrate Lyase Inhibitor Bempedoic Acid. Arterioscler Thromb Vasc Biol. 2017 Feb 2. pii: ATVBAHA.116.308963.
  7. Deng Z, Dong M, Wang Y, Dong J, Li SS, Zou H, Ye M. Biphasic Affinity Chromatographic Approach for Deep Tyrosine Phosphoproteome Analysis. Anal Chem. 2017 Feb 21;89(4):2405-2410.
  8. Tse WH, Gyenis L, Litchfield DW, Zhang J. Cellular interaction influenced by surface modification strategies of gelatin-based nanoparticles. J Biomater Appl. 2017 Feb;31(7):1087-1096.
  9. Wills MK, Keyvani Chahi A, Lau HR, Tilak M, Guild B, New LA, Lu P, Jacquet K, Meakin SO, Bisson N, Jones N. Signalling Adaptor ShcD Suppresses Erk Phosphorylation Distal to the Ret and Trk Neurotrophic Receptors. J Biol Chem. 2017 Feb 17. pii: jbc.M116.770511.
  10. Szabo PA, Goswami A, Mazzuca DM, Kim K, O'Gorman DB, Hess DA, Welch ID, Young HA, Singh B, McCormick JK, Haeryfar SM. Rapid and Rigorous IL-17A Production by a Distinct Subpopulation of Effector Memory T Lymphocytes Constitutes a Novel Mechanism of Toxic Shock Syndrome Immunopathology. J Immunol. 2017 Feb 20. pii: 1601366.
  11. Arpino JM, Nong Z, Li F, Yin H, Ghonaim NW, Milkovich S, Balint B, O'Neil C, Fraser GM, Goldman D, Ellis CG, Pickering JG. 4D Microvascular Analysis Reveals that Regenerative Angiogenesis in Ischemic Muscle Produces a Flawed Microcirculation. Circ Res. 2017 Feb 7. pii: CIRCRESAHA.116.310535.
  12. Xu Y, Pickering JG, Nong Z, Ward AD. Segmentation of digitized histological sections for quantification of the muscularized vasculature in the mouse hind limb. J Microsc. 2017 Feb 20.
  13. Balci TB, Hartley T, Xi Y, Dyment DA, Beaulieu CL, Bernier FP, Dupuis L, Horvath G, Mendoza-Londono R, Prasad C, Richer J, Yang XR, Armour CM, Bareke E, Fernandez BA, McMillan HJ, Lamont R, Majewski J, Parboosingh J, Narayan Prasad A, Rupar T, Schwartzentruber J, Smith AC, Tétreault M, Micheil Innes A, Boycott KM. Debunking Occam's razor: Diagnosing multiple genetic diseases in families by whole exome sequencing. Clin Genet. 2017 Feb 7.
  14. Bahrami SB, Tolg C, Peart T, Symonette C, Veiseh M, Umoh JU, Holdsworth DW, McCarthy JB, Luyt LG, Bissell MJ, Yazdani A, Turley EA. Receptor for hyaluronan mediated motility (RHAMM/HMMR) is a novel target for promoting subcutaneous adipogenesis. Integr Biol (Camb). 2017 Feb 20.
  15. Tolg C, Yuan H, Flynn SM, Basu K, Ma J, Tse KC, Kowalska B, Vulkanesku D, Cowman MK, McCarthy JB, Turley EA. Hyaluronan modulates growth factor induced mammary gland branching in a size dependent manner. Matrix Biol. 2017 Feb 20. pii: S0945-053X(16)30266-9.

Jan 2017

  1. McGee J, Panabaker K, Leonard S, Ainsworth P, Elit L, Shariff SZ. Genetics Consultation Rates Following a Diagnosis of High-Grade Serous Ovarian Carcinoma in the Canadian Province of Ontario. Int J Gynecol Cancer. 2017 Jan 9.
  2. Tamming RJ, Siu JR, Jiang Y, Prado MA, Beier F, Bérubé NG. Mosaic expression of Atrx in the central nervous system causes memory deficits. Dis Model Mech. 2017 Jan 12. pii: dmm.027482.
  3. Bazzi ZA, Balun J, Cavallo-Medved D, Porter LA, Boffa MB. Activated thrombin-activatable fibrinolysis inhibitor attenuates the angiogenic potential of endothelial cells: potential relevance to the breast tumour microenvironment. Clin Exp Metastasis. 2017 Jan 25.
  4. Hoffman KS, O'Donoghue P, Brandl CJ. Mistranslation: from adaptations to applications. Biochim Biophys Acta. 2017 Jan 30. pii: S0304-4165(17)30039-9.
  5. Ettinger G, Burton JP, Gloor GB, Reid G. Lactobacillus rhamnosus GR-1 Attenuates Induction of Hypertrophy in Cardiomyocytes but Not through Secreted Protein MSP-1 (p75). PLoS One. 2017 Jan 13;12(1):e0168622.
  6. Al K, Sarr O, Dunlop K, Gloor GB, Reid G, Burton J, Regnault TR. Impact of birth weight and postnatal diet on the gut microbiota of young adult guinea pigs. PeerJ. 2017 Jan 3;5:e2840.
  7. Badalato L, Farhan SM, Dilliott AA; Care4Rare Canada Consortium., Bulman DE, Hegele RA, Goobie SL. KMT2D p.Gln3575His segregating in a family with autosomal dominant choanal atresia strengthens the Kabuki/CHARGE connection. Am J Med Genet A. 2017 Jan;173(1):183-189.
  8. Hunter PM, Hegele RA. Functional foods and dietary supplements for the management of dyslipidaemia. Nat Rev Endocrinol. 2017 Jan 30.
  9. Burke AC, Huff MW. ATP-citrate lyase: genetics, molecular biology and therapeutic target for dyslipidemia. Curr Opin Lipidol. 2017 Jan 5.
  10. Li SS, Li L. SH2 Ligand Prediction-Guidance for In-Silico Screening. Methods Mol Biol. 2017;1555:77-81.
  11. Huang H, Kaneko T, Sidhu SS, Li SS. Creation of Phosphotyrosine Superbinders by Directed Evolution of an SH2 Domain. Methods Mol Biol. 2017;1555:225-254.
  12. Liu H, Voss C, Li SS. Using Reciprocal Protein-Peptide Array Screening to Unravel Protein Interaction Networks. Methods Mol Biol. 2017;1555:429-436.
  13. Campbell PT, Rebbeck TR, Nishihara R, Beck AH, Begg CB, Bogdanov AA, Cao Y, Coleman HG, Freeman GJ, Heng YJ, Huttenhower C, Irizarry RA, Kip NS, Michor F, Nevo D, Peters U, Phipps AI, Poole EM, Qian ZR, Quackenbush J, Robins H, Rogan PK, Slattery ML, Smith-Warner SA, Song M, VanderWeele TJ, Xia D, Zabor EC, Zhang X, Wang M, Ogino S. Proceedings of the third international molecular pathological epidemiology (MPE) meeting. Cancer Causes Control. 2017 Jan 17.
  14. Klank RL, Decker Grunke SA, Bangasser BL, Forster CL, Price MA, Odde TJ, SantaCruz KS, Rosenfeld SS, Canoll P, Turley EA, McCarthy JB, Ohlfest JR, Odde DJ. Biphasic Dependence of Glioma Survival and Cell Migration on CD44 Expression Level. Cell Rep. 2017 Jan 3;18(1):23-31.