PH.D. University of Nottingham
B.Sc. Northwest University
Office: Victoria Research Labs, Room A5-132
p. 519.685.8500 x. 55069
See Publications by Kaiping Yang on PubMed
Areas of research interests include:
- Glucocorticoid actions and metabolism in pregnancy/fetal development
- Glucocorticoid actions and metabolism in obesity and its associated metabolic disorders
- Molecular basis of intrauterine growth restriction
- Fetal origins of visceral obesity
- Effects of environmental pollutants/toxins on placental function and fetal development
Both in vivo (animal models) and in vitro (cell cultures and human tissues) as well as classic physiological/biochemical and modern molecular, proteomics and functional genomics approaches/techniques are being utilized.
Yang K, Julan L, Rubio F, Sharma A & Guan H (2006). Cadmium reduces 11B-hydroxysteroid dehydrogenase type 2 activity and expression in human placental trophoblast cells. Am J Physiol Endocrinol Metab 290(1):E135-E142.
Julan L, Guan H, van Beek JP & Yang K (2005). PPAR? suppresses 11B-hydroxysteroid dehydrogenase type 2 gene expression in human placental trophoblast cells. Endocrinology 146, 1482-1490.
Guan H, Arany E, van Beek JP, Chamson-Reg A, Thyssen S, Hill DJ & Yang K (2005). Adipose tissue gene expression profiling reveals distinct molecular pathways that define visceral adiposity in the offspring of maternal protein restricted rats. Am J Physiol Endocrinol Metab 288, E663¨CE673.
Guan H, Dy J, Richardson B & Yang K (2005). Identification of two novel allelic variants ofESX1L in the human placenta: lack of an association with intrauterine growth restriction. Placenta 26, 766-772.
Yang K (1997). Placental 11B-hydroxysteroid dehydrogenase: barrier to maternal glucocorticoids. Reviews of Reproduction 2(3), 129-132