Dr. Nathalie BerubeAssociate Professor (Basic Scientist in Paediatrics)
Office: LRCC VRL A4 138
Phone: 519-685-8500 Ext. 55066
My current work centers on the epigenetic regulation of brain development through the study of proteins that dictate chromatin structure, cell cycle progression and in neuronal function. Her recent work on ATRX gain and loss-of function mouse models has greatly advanced the understanding of the role of chromatin remodelling complexes in neuronal survival and differentiation. Her current work centers on the ATRX protein and its role as an epigenetic regulator of gene transcription by modulating chromatin accessibility and DNA methylation.