Dr. Alison Allan

Alison AllanDepartment Chair & Professor (Joint Appointment with Oncology)

Ph.D. University of Guelph
B.Sc. University of Guelph

Office:;Medical Sciences Building, 443A
Phone:
519-661-2111 Ext. 84054
Fax:
519-685-8616
Email:
alison.allan@lhsc.on.ca
Visit: Dr. Allan's Home Page

Research Interests:

Dr. Allan’s research interests lie in the study of molecular mechanisms that influence normal cellular growth, tumor development, and cancer progression. The focus of Dr. Allan’s research program is cancer metastasis and translational research. Despite the fact that the majority of deaths from solid cancer occur due to the physiological effects of metastasis rather than from the consequences of the primary tumor, metastasis remains a badly understudied field. A major area of research that is needed to address this problem involves gaining a greater understanding of the metastatic process as a whole, such that current therapies can be better utilized to target metastatic disease, and new, more effective therapies can be developed which will better treat or prevent cancer metastasis. A second important area of research is the identification and development of surrogate marker approaches that will allow close monitoring of both disease progression and response to therapy. Dr. Allan’s research program encompasses both of these areas, and involves two individual but interrelated projects.

Current Projects:

  1. Clinical and biological importance of circulating tumor cells (CTCs) in cancer patients and mouse models of metastasis

  2. Role of cancer stem cells (CSCs) in breast cancer metastasis and treatment

Publications:

For publications, please visit Dr. Allan's Google Scholar page or PubMed page.

Media and Video Links:

Western News, September 24, 2015: Research looks to deny cancer fertile ground in lungs

CTV2 London News, August 24, 2015: Breast cancer research gets a big boost

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