Schulich school of Medicine and Dentistry logo Mcalister Clinic Schulich School of Medicine & Dentistry

Transplant

We have published many papers on clinical and experimental transplantation (see PubMed list). We described the use of sirolimus in organ transplantation. We pioneered liposomal encapsulation of anti-rejection drugs.

Current project: We are investigating the interaction of anti-rejection drugs with anti-cancer drugs. Transplant recipients who develop cancer require both. We may learn more about the mechanism of action of each type of drug through the research so we can harness the interaction in the favour of the patient.

Recent project: We recently completed a single armed cross-over study to compare the effect of sirolimus to mycophenolate on recurrent hepatitis C virus after liver transplantation. The results are available here.