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• Mayur Brahmania

Mayur Brahmania

Dr. Mayur Brahmania is an Assistant Professor of Medicine at Western University practicing in Hepatology and Transplant Hepatology. He completed his undergraduate and medical degree at the University of Saskatchewan and eventually moved to Toronto for training in general and transplant Hepatology at the Toronto Centre for Liver Disease. He also undertook a research fellowship and earned a Masters of Public Health (MPH) degree at the Harvard TH Chan School of Public Health in Boston, MA. And holds advanced certification from the Centre for Quality Improvement and Patient Safety (CQUIPS).

Dr. Brahmania has been involved with the Choosing Wisely Canada (CWC) campaign as the Canadian Association for the Study of Liver Quality Lead. In this leadership role, he led the development of the 'top 5' list recommendations for Hepatology and his group is currently working to develop strategies to benchmark quality indicators for liver disease across Canada. He also works with CWC on the “Diving into Overuse in Hospitals” campaign to promote Choosing Wisely principles in Canadian hospitals. Locally, he is the program lead at Western for the Royal College’s STARS (Students Advocating for Resource Stewardship) campaign to develop quality improvement learning and principles for Medical Schools in Canada.

Dr. Brahmania is the current chair of the Gastroenterology Quality Improvement and Innovation Committee at Western University and currently focuses his research interests around quality improvement initiatives to advance and standardize quality of care in patients living with liver disease; many of these leading to publications in peer reviewed journals and presentation. He is also active in promoting quality improvement and patient safety within an educational setting by instructing and supervising resident quality improvement projects, teaching to medical students, business students and students from other healthcare disciplines. He is currently Co-Director of the LHSC Healthcare Excellence Incubator, an innovative course where healthcare and IVEY business students learn together about quality improvement principles and implementation within a business framework.

Selected Publications

Aziz S, Sey M, Marotta P, Driman D, Parfitt J, Teriaky A, Brahmania M, Skaro A, Qumosani K. Recurrent Hepatocellular Carcinoma After Liver Transplantation: Validation of a Pathologic Risk Score on Explanted Livers to Predict Recurrence. Transplant Proc, 2021 Jul 13, Coauthor, DOI: 10.1016/j.transproceed.2021.05.007.

Diaz L, Idalsoaga F, Fuentes-Lopez E, Marquez-Lomas A, Ramirez C, Roblero JP, Araujo R, Tijera F, Toro L, Pazmino G, Montes P, Hernandex N, Mendizabal M, Corsi O, Ferreccio C, Lazo M, Brahmania M, Singal A, Bataller R, Arrese M, Arab JP. Impact of public health policies on alcohol associated liver disease in Latin America: An ecological multi-national study. Hepatology, 2021 Jun 16, Coauthor, DOI:10.1002/hep.32016.  

Farag MS, Fung S, Tam E, Doucette K, Wong A, Ramji A, Conway B, Cooper C, Tsoi K, Wong P, Sebastiani G, Brahmania M, Haylock-Jacobs S, Coffin CS, Hansen BE, Janssen HLA. Effectiveness and Renal Safety of Tenofovir Alafenamide Fumarate among Chronic Hepatitis B Patients: Real-World Study. J Viral Hepat, 2021 Mar 22, Coauthor, DOI: 10.1111/jvh.13500.

Alsager M, Neong SF, Gandhi R, Teriaky A, Tang E, Skaro A, Qumosani K, Lilly L, Galvin Z, Selzner N, Bhat MP, Puka K, Brahmania M. Liver transplantation in adult polycystic liver disease: the Ontario experience. BMC Gastroenterol, 2021 Mar 9; 21 (1): 115, Coauthor, DOI: 10.1186/s12876-021-01703-x.

Brahmania M, Alotaibi A, Mooney O, Rush B. Treatment in disproportionately minority hospitals is associated with an increased mortality in end-stage liver disease. Eur J Gastroenterol Hepatol, 2020 Sep 7, Principal Author, DOI: 10.1097/MEG.0000000000001860

Brahmania M, Wiskar K, Walley KR, Celi LA, Rush B. Lower household income is associated with an increased risk of hospital readmission in patients with decompensated cirrhosis. J Gastroenterol Hepatol, 2020 Jun 20, Principal Author, DOI: 10.1111/jgh.15153.

Al Draiweesh S, Ma C, Alkhattabi M, McDonald C, Nguyen TM, Beaton M, Chande N, Colquhoun P, Feagan BG, Gregor JC, Khanna R, Marotta P, Ponich T, Quan D, Qumosani K, Sandhu A, Sey M, Skaro A, Teriaky A, Wilson A, Yan B, Brahmania M, Jairath V. Safety of Combination Biologic and Antirejection Therapy Post-Liver Transplantation in Patients With Inflammatory Bowel Disease. Inflamm Bowel Dis, 2020 May 12; 26 (6): 949-959, Coauthor, DOI: 10.1093/ibd/izz244.

Brahmania M, Liu S, Wahed AS, Yim C, Hansen BE, Khalili M, Terrault NA, Lok AS, Ghany M, Wang J, Wong D, Janssen HLA, Hepatitis B Research Network. Alcohol, tobacco and coffee consumption and liver disease severity among individuals with Chronic Hepatitis B infection in North America. Ann Hepatol, 2020 Feb 8, Principal Author, DOI: 10.1016/j.aohep.2020.01.005.

Hindi Z, Congly S, Tang E, Skaro A, Brahmania M. Liver Transplant Tourism. Liver Transpl; 2020. p.276-282, Senior Responsible Author, DOI: 10.1002/lt.25692.

Pai RK, Kleiner DE, Hart J, Adeyi OA, Clouston AD, Behling CA, Jain D, Kakar S, Brahmania M, Burgart L, Batts KP, Valasek MA, Torbenson MS, Guindi M, Wang HL, Ajmera V, Adams LA, Parker CE, Feagan BG, Loomba R, Jairath V. Standardising the interpretation of liver biopsies in non-alcoholic fatty liver disease clinical trials. Aliment Pharmacol Ther, 2019 Nov 1; 50 (10): 1100-1111, Coauthor, DOI: 10.1111/apt.15503.

Sey MSL, Mohammed SB, Brahmania M, Singh S, Kahan BC, Jairath V. Comparative outcomes in patients with ulcer- vs non-ulcer-related acute upper gastrointestinal bleeding in the United Kingdom: a nationwide cohort of 4474 patients. Aliment Pharmacol Ther, 2019 Mar 1; 49 (5): 537-545, Coauthor, DOI: 10.1111/apt.15092.

Ufere NN, Brahmania M, Sey M, Teriaky A, El-Jawahri A, Walley KR, Celi LA, Chung RT, Rush B. Outcomes of in-hospital cardiopulmonary resuscitation for patients with end-stage liver disease. Liver Int, 2019 Feb 27, Co-Principal Author, DOI: 10.1111/liv.14079.

Rush B, Deol N, Teriyaki A, Sey M, Jairath V, Walley KR, Celi LA, Brahmania M. Lower 90-day Hospital Readmission Rates for Esophageal Variceal Bleeding After TIPS: A Nationwide Linked Analysis. J Clin Gastroenterol, 2019 Feb 27, Principal Author, DOI: 10.1097/MCG.0000000000001199.

Rush B, Fruhstofer C, Walley KR, Celi LA, Brahmania M. Palliative medicine and hospital readmissions in end-stage liver disease. BMJ Support Palliat Care, 2019 Feb 13, Principal Author, DOI: 10.1136/bmjspcare-2018-001635

Brahmania M, Lombardero M, Hansen BE, Terrault NA, Lok AS, Perrillo RP, Belle SH, Di Bisceglie AM, Feld JJ, Lee WM, Fried MW, Janssen HLA, Hepatitis B Research Network. Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection. Clin Gastroenterol Hepatol, 2019 Feb 8, Principal Author, DOI: 10.1016/j.cgh.2019.02.005.

Brouwer WP, Chan HL, Lampertico P, Hou J, Tangkijvanich P, Reesink HW, Zhang W, Mangia A, Tanwandee T, Montalto G, Simon K, Ormeci N, Chen L, Tabak F, Gunsar F, Flisiak R, Ferenci P, Akdogan M, Akyuz F, Hirankarn N, Jansen L, Wong Wai-Sun V, Soffredini R, Liang X, Chen S, Groothuismink ZM, Santoro R, Jaroszewicz J, Ozaras R, Kozbial K, Brahmania M, Xie Q, Chotiyaputta W, Xun Q, Pazgan-Simon M, Oztas E, Verhey E, Montanari NR, Sun J, Hansen BE, Boonstra A, Janssen H, GIANT-B Global Consortium. Genome Wide Association Study Identifies Genetic Variants Associated With Early And Sustained Response To (Peg)Interferon In Chronic Hepatitis B Patients: The GIANT-B Study. Clin Infect Dis, 2019 Feb 2, Coauthor, DOI: 10.1093/cid/ciz084.

Congly SE, Brahmania M. Variable access to antiviral treatment of chronic hepatitis B in Canada: a descriptive study. CMAJ Open, 2019 Jan 1; 7 (1): E182-E189, Senior Responsible Author, DOI: 10.9778/cmajo.20180108.

Rajoriya N, Brahmania M, J Feld J. Implications of Manganese in Chronic Acquired Hepatocerebral Degeneration. Ann Hepatol. 18; 2019. p.274-278, Coauthor, DOI: 10.5604/01.3001.0012.7938.

Brahmania M, Renner EL, Coffin CS, Yoshida EM, Wong P, Zeman M, Shah H. Choosing Wisely Canada-Top Five List in Hepatology: Official Position Statement of the Canadian Association for the Study of the Liver (CASL) and Choosing Wisely Canada (CWC). Ann Hepatol, 2019 Jan 1; 18 (1): 165-171, Principal Author, DOI: 10.5604/01.3001.0012.7908.

Brahmania M, Renner EL, Coffin CS, Yoshida EM, Wong P, Zeman M, Shah H. Choosing Wisely Canada-Top Five List in Hepatology: Official Position Statement of the Canadian Association for the Study of the Liver (CASL) and ChoosingWisely Canada (CWC). Ann Hepatol, 2018 Dec 13; 18 (1): 165-171, Principal Author, DOI: 10.5604/01.3001.0012.7908.

Oakland K, Kahan BC, Guizzetti L, Martel M, Bryant RV, Brahmania M, Singh S, Nguyen N, Sey MSL, Barkun A, Jairath V. Development, Validation, and Comparative Assessment of an International Scoring System to Determine Risk of Upper Gastrointestinal Bleeding. Clin Gastroenterol Hepatol, 2018 Sep 27, Coauthor, DOI: 10.1016/j.cgh.2018.09.039.

Tadrous M, Brahmania M, Martins D, Knowles S, Janssen HLA, Mamdani MM, Juurlink DN, Gomes T. Publicly Funded Oral Chronic Hepatitis B Treatment Patterns in Ontario over 16 Years: An Ecologic Study. J Manag Care Spec Pharm, 2018 May 1; 24 (5): 464-468, Coauthor, DOI: 10.18553/jmcp.2018.24.5.464.

Brahmania M, Ahmed O, Kelley M, Kowgier M, Khalili K, Beecroft R, Renner EL, Wong D, Shah H, Feld J, Janssen HLA, Sherman M. Wait Time for Curative Intent Radio Frequency Ablation is Associated with Increased Mortality in Patients with Early Stage Hepatocellular Carcinoma. Ann Hepatol, 2017 Sep 1; 16 (5): 765-771, Principal Author, DOI: 10.5604/01.3001.0010.2776.

Rush B, Walley KR, Celi LA, Rajoriya N, Brahmania M. Palliative Care Access for Hospitalized Patients with End Stage Liver Disease Across the United States. Hepatology, 2017 Jun 29, Senior Responsible Author, DOI: 10.1002/hep.29297.

Rush B, Brahmania M. Concerns for the Methodology and Results Described in “Palliative Care and Health Care Utilization for Patients With End-Stage Liver Disease at the End of Life”. Clinincal Gastroenterology Hepatology, 2017 Apr 7: 1641-1642, Senior Responsible Author, DOI: 10.1016/j.cgh.2017.04.003.

Brahmania M, Ahmed O, Kelley M, Wong D, Kowgier M, Khalili K, Beecroft R, Renner EL, Shah H, Feld J, Janssen HLA, Sherman M. Wait Time for Curative Intent Radio Frequency Ablation is Associated with Increased Mortality in Patients with Early Stage Hepatocellular Carcinoma. Ann Hepatol, 2017 Apr 1; 16 (5): 765-771, Principal Author, DOI: 10.5604/01.3001.0010.2776.