Associate Professor of Neurology, Western University
Office: London Health Sciences Centre, University Hospital B10-106
Secretary: Lauren Malott
Dr. Mirsattari received his MD from Queen's University in Kingston, Ontario in 1995. He completed his neurology residency training at the University of Manitoba in 2000 and became a diplomate of the American Board of Psychiatry and Neurology in 2001. He was a postdoctoral research fellow of the Canadian Institutes of Health Research (CIHR) in clinical epileptology and neurophysiology at Western University until June 2004. He completed his PhD in neurophysiology in 2005. His postdoctoral research was on simultaneous EEG-fMRI/MR spectroscopy in an animal model of focal epilepsy and treatment of refractory status epilepticus.
Dr. Mirsattari is currently an Associate Professor in the Department of Clinical Neurological Sciences at Western University, London, Ontario. He joined CNS in 2004. He is one of the physicians involved in the Complex Epilepsy Surgery Program and Epilepsy/General Neurology Clinic at the London Health Science Centre. He also provides neurology consultation services to Health Sciences North Hospital (HSN) in Sudbury and Ontario Telestroke Network.
His professional activities have been multiple and include membership of the board of directors of the Canadian Neurosciences Federation (CNSF), Secretary treasurer/vice-President/President of the Canadian Society of Clinical Neurophysiologists (CSCN), CSCN EEG representative in the scientific committee of the CNSF, examiner for the national EEG examination, membership of the Student and Resident Education Committee of the American Epilepsy Society (AES). He has been a member of the American Academy of Neurology (AAN), AES, Society for Neurosciences (SFN), and the Canadian League Against Epilepsy (CLAE).
Dr. Mirsattari's main research interests are in the field of epilepsy, EEG and fMRI. His current projects include plasticity of the brain function especially in language and memory domains in patients with intractable epilepsy, functional connectivity mapping of brain functions using fMRI in patients that are candidates for epilepsy surgery, non-epileptic seizures, and development of new animal models of epilepsy.
Electroencephalography (EEG: measuring electrical activity of the brain), Epilepsy, Status Epilepticus (Persistant brain seizures), Magnetic Resonance Imaging (MRI), Seizures
Ikeda KM, Aldosari MM, Mirsattari SM, AlGhefari H, Hammond RR. Focal Cortical Dysplasia Type IIa Manifesting as Epilepsia Partialis Continua for 50 Years. Can J Neurol Sci. 2017 Oct 2:1-3. doi: 10.1017/cjn.2017.237. [Epub ahead of print] PubMed PMID: 28965498.
Mousavi SR, Arcaro JA, Leung LS, Tenney JR, Mirsattari SM. Functional connectivity of the hippocampus to the thalamocortical circuitry in an animal model of absence seizures. Epilepsy Res. 2017 Aug 24;137:19-24. doi: 10.1016/j.eplepsyres.2017.08.004. [Epub ahead of print] PubMed PMID: 28886474.
Farhan SMK, Nixon KCJ, Everest M, Edwards TN, Long S, Segal D, Knip MJ, Arts HH, Chakrabarti R, Wang J, Robinson JF, Lee D, Mirsattari SM, Rupar CA, Siu VM; FORGE Canada Consortium., Poulter MO, Hegele RA, Kramer JM. Identification of a novel synaptic protein, TMTC3, involved in periventricular nodular heterotopia with intellectual disability and epilepsy. Hum Mol Genet. 2017 Aug 16. doi: 10.1093/hmg/ddx316. [Epub ahead of print] PubMed PMID: 28973161.
Massot-Tarrús A, Mousavi SR, Mirsattari SM. Comparing the Intracarotid Amobarbital Test and Functional MRI for the Presurgical Evaluation of Language in Epilepsy. Curr Neurol Neurosci Rep. 2017 Jul;17(7):54. doi: 10.1007/s11910-017-0763-9. Review. PMID: 28623489
Climans SA, Mirsattari SM. Generalized epilepsy in Baraitser-Winter cerebrofrontofacial syndrome. Epilepsy Behav Case Rep. 2017 Mar 18;7:58-60. doi: 10.1016/j.ebcr.2017.03.003. eCollection 2017. PMID: 28413780
Ikeda KM, Mirsattari SM. Evolution of epilepsy in hemimegalencephaly from infancy to adulthood: Case report and review of the literature. Epilepsy Behav Case Rep. 2017 Mar 1;7:45-48. doi: 10.1016/j.ebcr.2017.02.002. eCollection 2017. PMID: 28377884
Gomez-Ibañez A, McLachlan RS, Mirsattari SM, Diosy DC, Burneo JG. Prognostic factors in patients with refractory idiopathic generalized epilepsy. Epilepsy Res. 2017 Feb;130:69-73. doi: 10.1016/j.eplepsyres.2017.01.011. Epub 2017 Jan 28. PMID: 28157601