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Dr. Chris J. Brandl

Dr. Christopher BrandlProfessor
B.Sc. Western University
Post-doctoral researcher, Harvard Medical School
Office: Molecular Biology Laboratory C210
Phone: 519.679.2111, ext. 86857
Fax: 519.661.3175

Mechanisms of transcriptional regulation

The ability of cells to activate gene expression in response to changes in the environment is crucial to all cellular processes. Defects in gene expression are a principal cause of human disease most notably cancer. My lab studies the mechanisms of transcriptional regulation using yeast as a model system to facilitate the combination of biochemical, molecular genetic and genetic techniques. Our principal focus is to determine the structure-function relationships and regulation of the SAGA complex that regulates transcription through the modification of chromatin structure.

Current studies include:


Complete list of publications from PubMed.