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Dr. Chris J. Brandl

Dr. Christopher BrandlProfessor
B.Sc. Western University
Post-doctoral researcher, Harvard Medical School
Office: Molecular Biology Laboratory C210
Phone: 519.679.2111, ext. 86857
Fax: 519.661.3175
E-mail: cbrandl@uwo.ca



Mechanisms of transcriptional regulation

The ability of cells to activate gene expression in response to changes in the environment is crucial to all cellular processes. Defects in gene expression are a principal cause of human disease most notably cancer. My lab studies the mechanisms of transcriptional regulation using yeast as a model system to facilitate the combination of biochemical, molecular genetic and genetic techniques. Our principal focus is to determine the structure-function relationships and regulation of the SAGA complex that regulates transcription through the modification of chromatin structure.

Current studies include:

Publications

Complete list of publications from PubMed.