Schulich school of Medicine and Dentistry logo Anesthesia and Perioperative Medicine Schulich School of Medicine & Dentistry

Centre for Medical Evidence, Decision Integrity & Clinical Impact (MEDICI)

Dr. Ava John-Baptiste

Centre for Medical Evidence, Decision Integrity & Clinical Impact

Mission & Vision

The MEDICI Centre is a university and citywide hospital-based program with three key mandates:

  1. To provide timely, contextualized evidence syntheses to enable evidence-based decision-making related to drugs, devices, procedures and programs in healthcare, with special focus on hospital based decision-making at the local level, but with relevance also to regional, national, and international healthcare decision-making;
  2. To provide educational opportunities for local decision-makers and students to build capacity in evidence-informed decision-making and health technology assessment, and to expand educational opportunities nationally and internationally to enable improved decision-making globally regarding decision-making and knowledge translation regarding health technologies and programs in the developed and developing world; and
  3. To conduct cutting-edge research to advance the front of health technology assessment, economic analysis, health policy analysis, decision-making sciences and knowledge translation.

Key Goals of the Unit


September 2013

MEDICI Program Director Dr. Janet Martin was invited to a Roundtable Meeting on Technological Innovation in Health Care with the Honorable Rona Ambrose, Federal Minister of Health in Toronto on September 9th 2013. Dr. Martin was one of 9 invited leaders of innovation in health care, and presented on the Know4Go Decision Support Framework and the work of the MEDICI Centre

Visiting Professors Dr. Myeongjong Lee (Konkuk University, Chungju Hospital) and Dr. Zhe Zhang (Fuwai Cardiovascular Hospital) joined the MEDICI Centre in September 2013. Dr. Lee and Dr. Zhang participated in several MEDICI Projects and developed their skills in the systematic review and meta-analysis process. Their projects included: Goal-Directed Therapy; Prehabilitation in Total Hip & Knee Arthroplasty; TAVI vs. Standard AVR; Ischemic Pre-conditioning

November 2013

In partnership with the Canadian Agency for Drugs and Technology in Health (CADTH), MEDICI co-hosted a Hospital/Regional HTA Symposium on Local Evidence-Based Decisions for Health Care Sustainability in Ottawa from November 18th-19th 2013. The symposium included leaders in hospital and regional-based health technology assessment from across Canada. Presentations are available online through CADTH’s website.

February 2014

MEDICI was joined by our first Postdoctoral Fellow, Dr. (Angel) Fang Zhu. Dr. Zhu completed her training at the Chinese University of Hong Kong and brings her experience in systematic review and meta-analysis to the team.

May - August 2014

We had an opportunity for several students to join us this year. Dr. John-Baptiste supervised three students over the summer (Young Zhou, Sivisan Suntheralingam, (Max) Yuan Qi) on a disinvestment project, and Amy Newitt (MLIS Candidate) joined the team in August 2014.

November 2014

MEDICI Program Director Dr. Janet Martin was invited to attend the Healthcare Innovation Panel with Dr. David Naylor and the Honorable Rona Ambrose, Federal Minister of Health in Toronto on November 25th, 2014. Dr. Martin was one of 35 stakeholders invited to a one-day regional consultation on healthcare innovation.

December 2014

MEDICI Directors, Drs. Martin & Cheng, were invited by the World Health Organization to participate in rapid guideline development for patients with surgical conditions in the context of Ebola Virus Disease




Habbous S, Garg AX, Martin JAppraisal of a redundant report on lanthanum carbonate. Int Urol Nephrol. 2016 Jan;48(1):149-50.

Martin J, Tau G, Cherian MN, Vergel de Dios J, Mills D, Fitzpatrick J, Adu-Krow W, Cheng D. Survey of the capacity for essential surgery and anaesthesia services in Papua New Guinea. BMJ Open. 2015 Dec 16;5(12):e009841. 

Wang L, Johnston B, Kaushal A, Cheng D, Zhu F, Martin JKetamine added to morphine or hydromorphone patient-controlled analgesia for acute postoperative pain in adults: a systematic review and meta-analysis of randomized trials. Can J Anaesth. 2015 Dec 10.

Jasudavisius A, Arellano R, Martin J, McConnell B, Bainbridge D. A systematic review of transthoracic and transesophageal echocardiography in non-cardiac surgery: implications for point-of-care ultrasound education in the operating room. Can J Anaesth. 2015 Oct 30. 

Martin J, Cheng D. The real cost of care: focus on value for money, rather than price-tags. Can J Anaesth. 2015 Oct;62(10):1034-41.

Puskas JD, Martin J, Cheng DC, Benussi S, Bonatti JO, Diegeler A, Ferdinand FD, Kieser TM, Lamy A, Mack MJ, Patel NC, Ruel M, Sabik JF 3rd, Yanagawa B, Zamvar V. ISMICS Consensus Conference and Statements of Randomized Controlled Trials of Off-Pump Versus Conventional Coronary Artery Bypass Surgery. Innovations (Phila). 2015 Jul-Aug;10(4):219-29.

Ariyan S, Martin J, Lal A, Cheng D, Borah GL, Chung KC, Conly J, Havlik R, Lee WP, McGrath MH, Pribaz J, Young VL. Antibiotic prophylaxis for preventing surgical-site infection in plastic surgery: an evidence-based consensus conference statement from the American Association of Plastic Surgeons. Plast Reconstr Surg. 2015 Jun;135(6):1723-39.

Bainbridge D, Cheng DC. Early extubation and fast-track management of off-pump cardiac patients in the intensive care unit. Semin Cardiothorac Vasc Anesth. 2015 Jun;19(2):163-8.

Polisena J, Lavis JN, Juzwishin D, McLean-Veysey P, Graham ID, Harstall C, Martin J. Supporting the Use of Health Technology Assessments by Decision-Makers. Healthc Policy. 2015 May;10(4):10-5.

Zhu F, Gomersall CD, Ng SK, Underwood MJ, Lee A. A randomized controlled trial of adaptive support ventilation mode to wean patients after fast-track cardiac valvular surgery. Anesthesiology. 2015 Apr;122(4):832-40.

Rawal S, Barnett C, John-Baptiste A, Thein HH, Krings T, Rinkel GJ. Effectiveness of diagnostic strategies in suspected delayed cerebral ischemia: a decision analysis. Stroke. 2015 Jan;46(1):77-83.

Clarke JTR, Coyle D, Evans G, Martin J, Winquist E. Towards a functional definition of ‘rare disease’ for regulatory agencies and funding agencies. Value in Health 2014;17(8):757-61.

Chin CJ, Sowerby LJ, John-Baptiste A, Rotenberg RW. Reducing otolaryngology surgical inefficiency via assessment of tray redundancy. Journal of Otolaryngology: Head & Neck Surgery 2014; 43(1):46.

Martin J, Cheng D. Perioperative Blood Management: Cardiac Surgery. Waters J (editor). In Perioperative Blood Management: A Physician’s Handbook, 3rd Edition. AABB Press, Bethesda, Maryland, 2014.

Martin J, Fuller J, McConachie I. Fluid Management in ICU, Third Edition, McConachie I (editor) Cambridge University Press, 2014.

Winquist E, Coyle D, Clarke JTR, Coyle D, Evans G, Seager C, Chan W, Martin J. Application of a policy framework for the public funding of drugs for rare diseases. J Gen Intern Med. 2014 Aug 29; Suppl 3:S774-9. [Epub ahead of print]

Borger J, Martin J, Cheng D. Book Chapter: Pharmacology of Vasopressors and Inotropes. Textbook of Critical Care. Jaypee Brothers, 2014.

Chui J, Martin J, Cheng D. Acute decompensated heart failure and cardiogenic shock. Textbook fo Critical Care. Jaypee Brothers, 2014.

Martin J, Cheng D. Perioperative Blood Management: Cardiac Surgery. Waters J (editor). In Perioperative Blood Management: A Physician’s Handbook, 3rd Edition. 2014.

Coronado A, Singh H, Martin J, Costella J, Malvankar M, Hodge W. Diagnostic Accuracy of Tele-ophthalmology Alternatives for Diabetic Retinopathy Screening: A Meta-analysis. ARVO Annual Meeting Abstracts, 2014.

Coronado A, Zaric G, Martin J, Malvankar M, Hodge W. Tele-ophthalmology versus in-person examination for diabetic retinopathy screening in Southwestern Ontario: a cost- effectiveness analysis. ARVO Annual Meeting Abstracts, 2014.

Winquist E, Coyle D, Clarke JTR, Evans G, Seager C, Chan W, Martin JApplication of a policy framework for the public funding of drugs for rare diseases. J Gen Intern Med. 2014 Aug;29 Suppl 3:S774-9.

Bardou M, Martin J. The increasing need for health-economic assessment in gastrointestinal and liver diseases. Best Pract Res Clin Gastroenterol. 2013;27(6):829-30.

Tanios N, Wagner M, Tony M, Baltussen R, van Til J, Rindress D, Kind P, Goetghebeur MM, Martin J, with the International Task Force on Decision Criteria. Which criteria are considered in health care decisions: Insights from an international survey of policy and clinical decision-makers. Int J Technol Asses Health Care 2013;29(4):456-65.

Martin J, Cheng D. Role of the anesthesiologist in the wider governance of healthcare and health economics. Can J Anesth 2013;60(9):918-928.

Neumann I, Letelier LM, Rada G, Claro JC, Martin J, Howden CW, Yuan Y, Leontiadis GI. Comparison of different regimens of proton pump inhibitors for acute peptic ulcer bleeding. Cochrane Database Syst Rev 2013 Jun 12;6:CD007999.

Coyle D, Bell CM, Clarke JTR, Evans G, Gadhok A, Martin J, Sabharwal M, Winquist E. Application of operations research to funding decisions for treatments with rare disease. Operations Res Health Care Policy. 2013;190:281-294.

Coyle D, Bell CM, Clarke JTR, Evans G, Gadhok A, Martin J, Sabharwal M, Winquist E. Applications of operations research to funding decisions for treatments with rare disease. In Zaric G (ed). Operations Research and Health Care Policy, SpringerLink 2013.

Martin J, Wang L, Arango M, Harle C, Cheng DC. Dexmedetomidine for awake fibreoptic intubation: A meta-analysis. Canadian Anesthesiologists Society Annual Meeting Abstracts, 2013, #1653026.

Bainbridge D, Martin J, Arango M, Cheng DAnaesthetic-related mortality in sub-Saharan Africa – Authors’ reply. Lancet. 2013;381(9862):199-200.


Know4Go: An Instrument for decision-making when resources are limited and demands are relentless

Special Presentation by Dr. Janet Martin for the Oxford University Centre for Evidence Based Medicine. 

Courses & Workshops

Under construction

Awards & Recognitions

Under construction


In 2011 with the support of the Schulich School of Medicine and Dentistry (SSMD), London Health Sciences Centre (LHSC) and Lawson Research, we are establishing a MEDICI Centre (Medical Evidence, Decision Integrity, Clinical Impact) to be the first hospital-based, evidence-based health technology assessment program in Ontario. This program will seek to involve other hospitals and the Ministry of Health and Long-term Care (MOHLTC) to build network capacity to answer high priority healthcare questions in a timely, transparent and accountable manner.

Evidence-based Decision Making and Health Technology Assessment (HTA) workshops and courses at the Schulich School of Medicine and Dentistry and cross-faculty within Western, will be established and likewise, a network with an international consortium of universities to provide an International MSc (HTA) program.

The Network will generate new hypotheses for innovative research in applied decision-making and knowledge translation techniques to address key evidence gaps and translation gaps related to the constant tension between available technologies and resources in healthcare.


  • Janet Martin, PharmD, MSc(HTA&M), Program Director
  • Davy Cheng, MD, FRCPC, Medical Director
  • Avtar Lal, MD, PhD, Systematic Reviewer
  • Ava John-Baptiste, PhD, Health Economist
  • Aiswarya Chandran, MD, Research Associate
  • Jessica Moodie, MLIS, Program Coordinator & Information Specialist
  • Trainees:
    • Angel (Fang) Zhu, MD, PhD, Postdoctoral Fellow
    • Jennifer Vergel de Dios, MD, MPH, Research Fellow
    • Amy Newitt, Project Assistant


Under construction