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Dr. Craig Railton

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Associate Professor

Biography

Dr. Railton received his B.Sc. in chemistry from Western University and completed his Ph.D. in synthetic Organic Chemistry at the University of Alberta. Following the completion of postdoctoral fellowships studying the carbohydrate chemistry of cell surface markers (University of Alberta) and chiral synthesis using C2-oxazoladinones (Danish Technical University), he completed medical school at the University of Toronto in 2000. Dr. Railton completed specialization in anesthesiology and completed his fellowship in clinical pharmacology in 2006.

Following completion of his fellowship training, Dr. Railton joined the Department of Anesthesia and Perioperative Medicine at Western University in 2006. He was cross appointed to the Department of Clinical Pharmacology shortly thereafter.

Dr. Railton's research interest is in the field of perioperative medicine. The goal is to improve patient safety by improving the medical management of patients during the perioperative time period. Dr. Railton is interested in understanding the effects of cardiovascular medications under anesthesia particularly in the setting of altered pharmacology and physiology caused by anesthesia. The role of individual differences in caused by pharmacogenetics plays an important role in understanding these changes and bringing personalized medicine to the perioperative time period.

His research projects include the role of pharmacogenetics in beta-blocker metabolism under anesthesia. Additional projects are aimed at understanding the altered physiologic response to inhaled anesthetic agents seen in patients with blocked renin-angiotensin systems and eventually understanding the role pharmacogenetics may play in these patients.

Recent Publications

Railton C. Chapter 5: Perioperative cardiovascular medication management. In: McConachie I, editor. Anesthesia and Perioperative Care of the High-Risk Patient. Cambridge, UK: Cambridge University Press; 2014.

Railton CJ, Wolpin J, Lam-McCulloch J, Belo SE. Renin-angiotensin blockade is associated with increased mortality after vascular surgery. Can J Anaesth. 2010 Aug;57(8):736-44. Epub 2010 Jun 4.